Podcasts about urticaria

Hola :) En el episodio de hoy os voy a hablar de todo lo relacionado con la amina biogena que produce nuestro cuerpo de manera normal y qué cuando esta en equilibrio es clave para el sistema inmune, la memoria, el manejo del dolor, la producción de acido estomacal y el control del apetito PERO que cuándo está en exceso, puede darnos lugar a sintomas y signos tan "poco" relacionados entre sí como:Urticaria, picor de la pielDistensión abdominal, dolor abdominal, diarreasMoqueo nasal, picor nasal, tos, lagrimeo continuoHipotensión taquicardiaDolor muscular y articularAdemas os contatré cuales pueden ser los origenes endogenos (nuestro cuerpo) y exogenos (la dieta o fármacos) de la acumulación de histaminaQué podemos hacer para diagnosticar el exceso de histamina, descartando antes la mastocitosis, el sindrome de activación mastocitaria, enfermedades como enfermedad celiaca, situaciones autoinmunes ...Qué alimentos son altos en histamina, cuales son bajosSuplementos que pueden ayudar: quercetina, vitamina D, butirato, trans resveratrol, probioticos como L. rhamnosus GG, L. plantarum...Para mas información ya sabéis que me tenéis en mi instagram @isabelvina dónde te comparto contenido diario Mi TikTok @isabelvinabas En mi canal de YouTube https://www.youtube.com/channel/UC-dfdxLBcvfztBvRAKZSXGQ Y los suplementos formulados por mi https://ivbwellness.com

In this episode of The Health Fix Podcast, Dr. Jannine Krause sits down with Nicole Bonneville, a video media and marketing expert and cohost of the Homance Chronicles on Women in History. Nicole is dedicated to spreading awareness of chronic health and autoimmune conditions to help others find answers faster. Nicole shares her journey—from being stopped at border patrol for being radioactive in her teens to navigating chronic Urticaria, GERD, and the frustrating runaround from the medical system. She opens up about the emotional toll, financial strain, and repeated dead ends, while also providing practical self-advocacy tips for those facing similar struggles. What You'll Learn In This Episode: Why hives often stem from internal, not external, sources The connection between gut health, histamine, and autoimmune conditions How to advocate for yourself when doctors don't have answers What to say when your doctor refuses to run more tests The power of having a program to track symptoms Why condition-focused groups provide more value than Google searches The importance of trusting your intuition on your health journey Resources From The Show:

Urticaria is a skin reaction that causes itchy welts. Chronic hives are welts that last for more than six weeks and return often over months or years. What causes it and what the treatment? To discuss further Pat spoke to Selene Daly Tarpey, Nurse Tutor and Registered Advanced Nurse Practitioner.

With a range of treatments available to treat moderate to severe psoriasis, it can be tough to navigate the landscape. Kara Gooding, MMS, PA-C and Joe Gorelick, MSN, FNP-C provide updates on pathogenesis and the latest treatments. Plus, Jayme Heim, MSN, FNP-BC addresses the diagnosis of CSU and Ted Rosen, MD talks about the challenges of diagnosing STIs. Like what you're hearing? Want to learn more about the Dermatology Education Foundation? Explore assets and resources on our website.

Episode 103 – What steps can be taken to manage solar urticaria? Professor Torsten Zuberbier and Dr Lea Kiefer examine solar urticaria, discussing the role of skin type, management strategies, and treatment methods.

Episode 102 – Professor Torsten Zuberbier welcomes Dr Luis Ensina to discuss essential information for people with urticaria, highlighting the benefits of keeping a diary before medical appointments and how using patient-reported outcome tools can help doctors understand their condition better.

Episode 101 – What were the highlights at Global Urticaria Forum (GUF) 2024? Professor Torsten Zuberbier and Dr Sophia Neisinger share their live reflections on the 7th Global Allergy and Asthma Excellence Network GUF event, including personal highlights, tips for junior physicians to make meaningful contributions to meetings and details on GUF 2025. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria' podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

Aimar Bretos, sobre la ausencia de PP y VOX en el acto de mañana por la muerte de Franco

JACI: In Practice Editor Robert Zeiger describes the January issue, the theme of which is “Insect Sting Allergy”. Theme topics covered include venom component allergen IgE measurement, risk factors for severe sting reactions and side effects during venom immunotherapy, stinging ant anaphylaxis, mast cell disorders and hymenoptera venom-triggered anaphylaxis, large local reaction to insect stings, and shared decision making in the diagnosis and management of insect sting allergy. Dr. Zeiger then presents the Highlights of the Original Articles in the issue, which are on the topics of Insect Sting Allergy, Asthma, Drug Allergy, Eosinophilic Disorders, Food Allergy, Immunodeficiency, Mast Cell Disorders, and Urticaria

Zang Fu, the Organ Systems of Traditional Chinese Medicine: Functions, Interrelationships and Patterns of Disharmony in Theory and Practice Author: Jeremy Ross Page 240-246 Chapter 18-2 Case Histories 5. Urticaria and Stomach Pain Diagnosis Treatment Patient Education 6. Back, Shoulder, Breasts and Respiratory System Diagnosis Treatment Patient Education 7. Debilities and Insomnia Diagnosis Treatment Patient Education Reading and learning Texts about Traditional Chinese Medicine. The objective is to share great wisdom of Traditional Chinese Medicine, Ayurveda, and any kind of Alternative Medicine by posting my recording while I am reading English books at laud. It is my English learning and Natural medicine studying purpose. Hope those recordings help somebody learn and satisfy one's interests. Enjoy! Disclaimer: This video does not contain medical advice. All content is intended for informational purposes only and is not intended to substitute for medical advice, diagnosis, or treatment from your physician or other healthcare provider. Please consult your physician for personalized medical advice and for any questions regarding a medical condition. Tag Traditional Chinese Medicine, Alternative Medicine, Natural Medicine, Holistic Health, Wellbeing

Episode 100 – In this special episode, recorded on Urticaria Day (UDAY), Professor Torsten Zuberbier and Dr Carolina Vera welcome CSU patient advocate Kristen Willard, who shares her story of living with urticaria. With live audience participation, this episode also delves into the cause of itch, the impact of urticaria on mental health, and novel treatments. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria' podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry. 

Discover Meka's journey with chronic hives in skin of color—a powerful story of resilience, self-advocacy, and building the right support system to get the care she deserves. Emmeka, or "Meka," joins Dr. Gupta and Kortney to share her personal experience of living with chronic urticaria as a person with skin of color. Meka describes her journey from a lack of resources addressing hives on black skin to finding effective support and resources. She opens up about the long path to her diagnosis, the depth of her online research into chronic spontaneous urticaria (CSU), and the importance of finding knowledgeable, empathetic healthcare providers. Meka's optimism highlights how a proactive approach, a trusted care team, and a strong support network can make a difference in managing CSU. What we cover in our episode about living with hives in black skin: Identifying Hives on Darker Skin: Meka shares the challenge of finding accurate images of hives on darker skin tones, which can complicate the first steps of recognizing your condition and create feelings of isolation. Advocating for Yourself in Healthcare: Meka provides strategies for effective self-advocacy during the diagnosis process, including tips for clear communication with healthcare providers. Building a Support Network: Meka emphasizes the value of connecting with others who share similar experiences, including support groups and online communities. Managing Symptoms & Minimizing Scars: Meka offers practical advice for managing CSU symptoms, reducing scarring, and strategies to avoid scratching.

En este episodio especial de La Galería Nocturna, exploramos el cartel del MXMF Metal Fest 2024, que se llevará a cabo en el ya emblemático Velódromo de la Ciudad de México el próximo 16 y 17 de noviembre. Este festival se perfila como el evento de metal más importante desde 2019, presentado por Cacique Entertainment, y promete una experiencia única para los fans del género. Con un cartel colosal que incluye a algunas de las bandas más legendarias, destacamos a Hypocrisy, Satyricon, DeathLock, , Sonata Arctica, Chelsea Green, Cynic, Urticaria 4n4l, Hate. 1349, Pestilence, junto a muchas otras que conforman una alineación poderosa y diversa. En este capítulo, analizamos lo que cada uno de estos gigantes del metal aportará la escena metalera en México. ¡Prepárate para descubrir cada detalle de este impresionante festival y para contagiarte de la adrenalina que está a punto de desatarse en el Velódromo!

Chronic hives (urticaria) don't look the same on everyone, and for people with skin of color, this can lead to confusion, misdiagnosis, and frustrating delays in treatment. Dr. Ama Alexis joins Dr. Gupta and Kortney to discuss the unique challenges of diagnosing and managing urticaria in skin of color. Chronic spontaneous urticaria (CSU) can be especially tricky to identify in patients with darker skin tones, where traditional medical resources and visual aids often fall short. Dr. Alexis explains how CSU appears differently in skin of color, discussing the difficulty of capturing hives on black and brown skin and offering advice for photographing hives to share with your doctor. Dr. Gupta and Dr. Alexis also delve into the lack of diversity in clinical research and medical literature, exploring how these gaps contribute to mistrust and delays in treatment for patients of color. We end with a discussion on whether patients have better outcomes with providers who reflect the patient's background. What we cover in our episode about chronic urticaria in skin of color: Identifying CSU in Darker Skin Tones: Dr. Alexis shares insights on how hives appear on darker skin and gives tips for photographing hives accurately. Limited Visual Resources for Skin of Color: We discuss how a lack of reliable images for darker skin often leads to confusion and feelings of isolation. Provider Training and Diagnosis Delays: Dr. Alexis highlights how limited training in diagnosing skin conditions across all skin tones contributes to delays in care. Collaborating on a Treatment Plan: Tips for patients on advocating for inclusive care, with guidance on both over-the-counter and prescription options. Cultural Sensitivity in Healthcare: Dr. Alexis shares ways healthcare providers can foster shared decision-making to improve outcomes for patients of color. More resources about chronic hives in skin of color:  Chronic Urticaria Management, Resources & Glossary of Terms What is Chronic Urticaria Chronic Hives: 10 Actions to Support Mental Health Chronic Spontaneous Urticaria Series This episode is produced in partnership with Allergy & Asthma Network, with special thanks to Genentech for sponsoring this episode.

Bytes of Health is a daily, five-minute long podcast that provides practical guidance and advice for parents of kids of all ages! It's a shame-free zone that aims to take a "byte" out of your parent worries! Be sure to subscribe, rate, and review Bytes of Health on Apple Podcasts, Spotify, Amazon, or wherever you get your podcasts. And find us on Instagram at https://www.instagram.com/bytesofhealthpod/ Interested in advertising with us? Please reach out to advertising@airwavemedia.com, with “Bytes of Health” in the subject line. PLEASE NOTE: The discussion and information provided in this podcast are for general educational, scientific, and informational purposes only and are not intended as, and should not be treated as, medical or other professional advice for any particular individual or individuals. Every person and medical issue is different, and diagnosis and treatment requires consideration of specific facts often unique to the individual. As such, the information contained in this podcast should not be used as a substitute for consultation with and/or treatment by a doctor or other medical professional. If you are experiencing any medical issue or have any medical concern, you should consult with a doctor or other medical professional. Further, due to the inherent limitations of a podcast such as this as well as ongoing scientific developments, we do not guarantee the completeness or accuracy of the information or analysis provided in this podcast, although, of course we always endeavor to provide comprehensive information and analysis. In no event may Unbiased Science or any of the participants in this podcast be held liable to the listener or anyone else for any decision allegedly made or action allegedly taken or not taken allegedly in reliance on the discussion or information in this podcast or for any damages allegedly resulting from such reliance. The information provided herein do not represent the views of our employers. Learn more about your ad choices. Visit megaphone.fm/adchoices

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This episode was recorded before 31 July 2024. Professor Marcus Maurer, Dr Carolina Vera Ayala, and Associate Professor Jonny Peter discuss how new therapeutics progress through the development pipeline, noting the “huge amount of data” required on safety before a molecule enters clinical trials. They also shed light on drug repurposing and why children are a “critical group” for inclusion in trials. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Chronic urticaria: unmet needs, emerging drugs, and new perspectives on personalised treatment Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria' podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry. 

Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from September 21-September 27, 2024.

Chronic spontaneous urticaria affects approximately 1% of the general population worldwide, impairs patients' quality of life, and is associated with multiple comorbidities. Pavel Kolkhir, MD, discusses the current evidence on the epidemiology, pathophysiology, diagnosis, and treatment of chronic spontaneous urticaria with JAMA Senior Editor Karen E. Lasser, MD, MPH. Related Content: Chronic Spontaneous Urticaria

[This episode was recorded before 31 July 2024.] "Every chronic urticaria starts as acute urticaria, but not every acute urticaria becomes chronic." Associate Professor Dr Andaç Salman and Professor Marcus Maurer discuss causes of acute urticaria, how diagnosis and management can be improved, and UCARE's research into drivers of “chronification”. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Acute and chronic urticaria diagnosis and management taking into account their differences; Acute urticaria – GA2LEN UCARE 2023 conference presentation and Project: CHAPEAU – GA2LEN UCARE Network Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria' podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry. 

New drug approved to treat ulcerative colitis; Once-weekly insulin efsitora investigated in type 1 diabetes; Dupilumab shows efficacy for treating urticaria; A twice-yearly injection shows potential for treating severe asthma; and GSK calls an end to their development of a herpes vaccine.

This episode was recorded before July 31, 2024. Professor Marcus Maurer and Dr Sigurd Broesby-Olsen discuss similarities and differences between urticaria and mastocytosis, two mast cell diseases. They then turn their attention to treatment, sharing their thoughts on ‘killing' mast cells and the development of more targeted and less toxic therapies. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Mast cell silencing: A novel therapeutic approach for urticaria and other mast cell-mediated diseases; Mast cell–targeting therapies in mast cell activation syndromes; and Tyrosine kinase inhibitors for the treatment of indolent systemic mastocytosis: Are we there yet? Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria' podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry. 

This is a free preview of a paid episode. To hear more, visit www.theflyingfrisby.comWhen I was 19, I started getting these weird heat rashes. Every day, whenever I got hot, these debilitating, paralysing heat rashes would envelop me. Burning, bumpy, red weals suddenly covered my body. So itchy—you wanted to scratch everywhere, though scratching brought no relief. Once the rash started, there was nothing I could do. I just had to wait for it to pass, which would take about half an hour.I didn't even have to get so hot that I broke sweat for the rash to come on. Just walking briskly would do it, getting flustered, wearing a layer too many, even having a shower.And it came every day, usually mid-morning.I thought it might be stress that was causing it, but it was the other way around: these rashes were causing the stress.I found a way of coping with it: do intense exercise every morning and actually induce the rash. Then it seemed to burn itself out for the rest of the day.But the next morning, it would be back again.I went to see doctors about it. None of them knew what it was. As GPs often do when they don't know the answer, they brushed it aside, “Oh, it's probably stress.” I wasn't making this up! But unless I actually had an attack in front of the GP, there was no way of showing them what it was.I saw a dermatologist, who gave me anti-depressants. I saw Chinese herbalist after Chinese herbalist, who all concocted these disgusting teas for me to drink. Lord knows what damage I did to my liver drinking that stuff. I saw an acupuncturist who declared brightly that he could cure it. But he couldn't.It made my life a nightmare, because you never quite knew when the rash was going to hit. What if it came on when I was on stage? During that all-important meeting? When I was with a girl I liked? It was a source of acute embarrassment.The condition disappeared, bizarrely, if I went to the tropics. Why, Lord knows. But as soon as I got home, back it came. Then I noticed the condition also disappeared in the summer. What was that about? I realised the antihistamine I was taking for hay fever also prevented these rash attacks.But I didn't want to take antihistamine every day—that couldn't be healthy—so, once the hay fever season was over, I would go back to keeping it at bay by trying to do intense exercise every morning and burning it off.When I got married and had kids, aged 30, this became impossible, so I resigned myself to daily antihistamine. This started with Clarityn (Loratadine), moved onto Zirtek (which I hated because if I drank alcohol, I used to get incredibly drunk and that led to a lot of bad decisions and mistakes) and, eventually, Xyzal, which I found I only needed to take every other day. The potential long-term damage of sustained anti-histamine use was a gamble I was prepared to make to avoid the daily nightmare of this condition.If you are buying gold to protect yourself in these uncertain times, then let me recommend The Pure Gold Company. Premiums are low, quality of service is high and you deal with a human being who knows their stuff. Eventually, I discovered that the problem I had was a condition called heat-induced cholinergic urticaria. I went to see a specialist at St Thomas' Hospital. “There is no cure,” she told me. “Sometimes it clears up by itself,” she told me, “sometimes not. You're lucky antihistamine stops it. For many that doesn't work.” I volunteered to be a guinea pig so she could experiment on me as part of her research into the condition. I would go to the hospital, have a hot bath, my skin would erupt, and then she'd prod me and prick me and nod and mutter, but it got me no nearer to a cure.Here I am at 54, and it has not cleared up.What is the cause?I'm still not quite sure if something I did caused it. Urticaria is from the same allergic school of illnesses as asthma, eczema, and hay fever, from which I suffer a little (asthma especially if I run or am near cats), so it might be hereditary or genetic. It affects young men more than any other group, which is what I was.I've been on numerous forums where fellow sufferers discuss the condition, and a lot of us took the antibiotic tetracycline. I took it for years as a teenager to help with my acne. God, it makes me cross that I was allowed—even encouraged—to take it for so long. Bloody doctors, or one in particular (no longer with us so I won't name him and speak ill of the dead), and my mother's blind trust in them. I thought it might be tetracycline.I had spent two months in Egypt just before I got my first outbreaks, and I got very ill with Giardia, a form of dysentary. Maybe I lost some essential bacteria in my stomach or something, or got leaky gut. (I've taken a million probiotics and all the rest of it—didn't work).Also just before the first outbreaks, I got the sh*t kicked out of me in a park in Milan by a group of young Italians - I mean properly beaten up, 7 v 1 and I made the mistake of fighting back - so maybe it was somehow related to that.Maybe it was the accumulation of everything.Nature's magic superfood comes to the rescueOne of the unintended benefits of my health drive in recent years is that my asthma, which I've had since I was born, appears to have, for no apparent reason, gone. I haven't been near cats to test it there, but I no longer need my puffer to play football. (Don't know why. It might be an age thing; a health thing, most likely a seed oil thing).Then I forgot to take my antihistamine for a few days, and I noticed that I wasn't getting urticaria attacks either. Praise the Lord! I thought my urticaria might've cleared up too. No such luck, as it turned out. It hadn't. I went abroad and, after a few days, it came back. Then I realised there was something I'd been taking at home, and I hadn't taken it away with me.It made all the difference.That mysterious ailment you've had for ages and can't rid of. this might sort that out too.

There's never been a better time to be a CSU patient, with cutting-edge therapies and revolutionary treatments just around the corner. As research accelerates, new and promising options that could significantly improve the quality of life for those living with Chronic Spontaneous Urticaria are coming to market. In this episode, Dr. Matthew Zirwas joins us to discuss the latest advancements in treating CSU, offering invaluable insights into both current and emerging treatment options. With his extensive experience and patient-centred approach, Dr. Zirwas breaks down the complexities of CSU and highlights how these new therapies can make a real difference. This podcast was made in partnership with Allergy & Asthma Network. We thank Novartis for sponsoring this podcast. What We Cover in Our Episode About Emerging Chronic Spontaneous Urticaria Treatments: How Dr. Zirwas explains CSU to his patients: Discover the patient-friendly explanations that help demystify CSU and empower patients to learn more about their disease. When to start with a biologic: Learn about the decision-making process for initiating biologic therapies like Xolair (omalizumab) and when they are most appropriate. The new medications coming to market: Get an overview of the latest advancements, including: Dupixent (dupilumab): A biologic administered via injection that targets key pathways in the inflammatory response. Remibrutinib: A BTK (Bruton tyrosine kinase) inhibitor available as a pill that blocks a crucial enzyme in mast cell activation. Barzolvolimab: A promising biologic that targets the C KIT receptor on mast cells to reduce their number. Shared decision-making with these medications: Explore strategies for choosing the most appropriate treatment in a rapidly evolving therapeutic landscape. Research into the underlying cause of CSU: What's happening on the research front to uncover the root causes of CSU. About Our Guest Dr. Matthew Zirwas, MD, is a board-certified dermatologist and a nationally recognized expert in allergy patch testing, psoriasis, and eczema. He founded the Bexley Dermatology Research Clinic, offering patients access to the latest treatment options before they are widely available. Dr. Zirwas also serves as a dermatologic advisor for several companies, including ALL Laundry Detergent and Cerave, and contributes to Women's Health Magazine. Learn more about Dr. Zirwas. More resources about chronic spontaneous urticaria:  Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/ What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/  More information about Omalizumab (Xolair): https://www.xolair.com/chronic-spontaneous-urticaria.html Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

"We will only be able to cure this disease and treat it well if we know how it works." Back by popular demand, Dr Jörg Scheffel rejoins Professor Marcus Maurer to discuss the importance and intricacies of mast cell research in urticaria.” Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: A novel approach for studying mast cell-driven disorders: Mast cells derived from induced pluripotent stem cells; and Isolation and Culture of Human Skin Mast Cells. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria' podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry. 

This episode is a quick-fire round covering the misunderstood aspects of chronic spontaneous urticaria (CSU), a condition that perplexes many due to its spontaneous nature. With over 1.7 million people affected, it's more common than you might think and deserves a closer look. Despite its prevalence, many misconceptions persist about what causes CSU, its symptoms, and how it can be treated. Kortney and Dr. Gupta tackle the myths and misconceptions around CSU. Unpacking its impacts on quality of life and the challenges those living with the condition face. They explore the realities of living with CSU, from the pervasive itch to the emotional toll it can take. Whether you're a patient, caregiver, or healthcare professional, this episode offers valuable insights into the realities of managing CSU. This podcast was made in partnership with Allergy & Asthma Network. We thank Novartis for sponsoring this podcast. The chronic spontaneous urticaria myths and misconceptions we cover in our episode CSU is caused by allergies. CSU is contagious. CSU is a rare condition. CSU is not a serious condition. Stress is the main cause of CSU. CSU only affects the skin. CSU will go away quickly. There isn't any treatment for chronic hives. Antihistamines are the only treatment for CSU. Changing your diet will help CSU. CSU can be cured. Once CSU goes away, it will never come back again. Men and women are equally affected by CSU. You can always pinpoint the exact cause of hives in patients with CSU. Autoimmune conditions are more common in people with CSU. Scratching hives is harmless. Once my hives are controlled, I need to be on the medication forever. All hives look the same. Only adults get CSU. CSU hives are always accompanied by other allergic symptoms like swelling or difficulty breathing. Having CSU doesn't affect quality of life. The itch in CSU is not a big deal. Allergy testing will help me figure out why I have CSU. More resources about chronic spontaneous urticaria:  Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/ What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/  More information about Omalizumab (Xolair): https://www.xolair.com/chronic-spontaneous-urticaria.html Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Dr Maryam Ali Al-Nesf joins Professor Marcus Maurer to discuss one of the big burdens of chronic urticaria: the "use, or should we say abuse, of cortisone" in chronic spontaneous urticaria. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Efficacy and safety of systemic corticosteroids for urticaria: A systematic review and meta-analysis of randomized clinical trials; and A patient charter for chronic urticaria. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria' podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry. Episode  100 will be held live on UDAY (1 October 2024, 14:30 CEST). Submit your questions in advance to info@ga2len-ucare.com. Follow UCARE on Instagram to be notified of more information https://www.instagram.com/ga2len_acare_ucare/.

Imagine being so itchy that you'd consider cutting off your skin just for relief. That's what it can be like living with chronic spontaneous urticaria. We sit down with Heather, a patient living with chronic spontaneous urticaria, as she candidly shares her experiences from the initial diagnosis to navigating the complex landscape of treatments and mental health support. Her story sheds light on the day-to-day struggles and triumphs of managing CSU, offering hope and practical advice for those in similar situations. Dr. G unpacks Heather's diagnosis and treatment journey, including antihistamines and Omalizumab. Dr. G also highlights the importance of managing mental health. Kortney shares her experience of itch and, with Heather, discusses the impact of chronic itching on quality of life and how to explain this to friends and family. What we cover in our episode about living with chronic spontaneous urticaria Heather's Journey with CSU: Heather shares her initial diagnosis and the rollercoaster of emotions and challenges that followed. Anaphylaxis vs. CSU: Understanding the critical differences between these two conditions. Finding the Right Treatment Plan: The journey to discovering effective medications like antihistamines and the injectable - Omalizumab (Xolair). Mental Health Support: The importance of therapy and online resources in managing life with CSU. Management strategies: Heather shares what works for her in managing exacerbating situations.  Advice for New Patients: Heather offers valuable advice for those beginning their CSU journey. More resources about chronic spontaneous urticaria:  Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/ What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/  More information about Omalizumab (Xolair): https://www.xolair.com/chronic-spontaneous-urticaria.html Episode Heather talks about where she learned to call her condition Lynda: https://www.itchpodcast.com/episodes/71-living-with-mastocytosis  Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

En junio y julio del 2024, estamos transmitiendo algunos de nuestros episodios más escuchados durante la tercera temporada. Reanudaremos con nuestra cuarta temporada en agosto del 2024. Muchas gracias a todos nuestros oyentes por su apoyo y por compartir nuestros episodios de "Pediatras en Línea". La urticaria es una de las afecciones cutáneas más comunes en niños y en este episodio haremos un recuento del ABC de la urticaria en pediatría. Analizamos los diferentes tipos que existen, causas, síntomas, diagnóstico y su tratamiento. Nuestra invitada es la Dra. Mónica Sandoval Ruballos, originaria de Guatemala. La Dra. Sandoval es alergóloga e inmunóloga pediatra. Graduada como médico y cirujano de la Universidad Francisco Marroquín. Realizó la maestría en ciencias médicas con especialidad en pediatría en el Hospital Roosevelt de Guatemala y posteriormente se formó como alergóloga e inmunóloga pediatra en el hospital Sant Joan de Déu en Barcelona. Actualmente se dedico a la práctica privada tanto en la ciudad de Guatemala como en el oriente del país. ¿Tienes algún comentario sobre este episodio o sugerencias de temas para un futuro podcast? Escríbenos a pediatrasenlinea@childrenscolorado.org.

Professor Christian Vestergaard and Professor Marcus Maurer discuss the link between obesity and urticaria, including how obesity contributes to chronic inflammation and the importance of P4 medicine (preventive, predictive, personalised, participatory) in urticaria treatment.  Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: High waist circumference rather than high body mass index may be a predictive risk factor for the longer disease duration of chronic spontaneous urticaria; and Risk of comorbidities in patients diagnosed with chronic urticaria: A nationwide registry-study. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria' podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

Yes, there are more options than antihistamines to treat chronic spontaneous urticaria. We dive into them!  Dr. Sheila Gogate joins us to discuss the chronic spontaneous urticaria (CSU) treatments currently available for patients. Dr. Shaila Gogate outlines the treatment journey for CSU with an emphasis on shared decision-making.   This episode emphasizes the importance of following treatment guidelines and adjusting medications as needed. We discuss the available treatments for urticaria, including antihistamines, omalizumab (Xolair for hives), and Cyclosporine. The episode also explores the journey of managing CSU symptoms through both medical and non-medical approaches. What we cover in our episode about chronic spontaneous urticaria treatments Treatment Path and Guidelines: Overview of doctors' steps to treat CSU. The importance of shared decision-making in the treatment plan.  Antihistamines: Role of oral antihistamines and H2 blockers in managing hives, dosing options, side effects, when to change medications, and how to choose the right antihistamine. Advanced Treatments: If antihistamines fail, the following steps include omalizumab (Xolair) injections or Cyclosporine. An overview of both dosing options and side effects. Emerging Therapies: Treatments like Remibrutinib and Dupilumab. Quality of Life and Non-Medical Management: The Urticaria Activity Score (UAS7). Mental health screening for CSU patients and strategies like stress reduction and if special diets are effective. About our guest, Dr. Shaila Gogate Dr. Shaila Gogate, board-certified by the American Board of Allergy & Immunology, has been with Colorado Allergy & Asthma Centers since 2014. She completed her medical education at Chicago Medical School, her residency at Washington University, and her fellowship at National Jewish Health in Denver. Dr. Gogate has served as an Assistant Professor at the University of Colorado, has extensive clinical research experience, and emphasizes strong patient-provider communication to develop effective treatment plans. More resources about chronic spontaneous urticaria:  Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/ What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/  How Mast Cells Work Video_ mast cell video - explanation of mast cell (07:20): https://youtu.be/OF7tBIvMK_0?si=osJaIpTrivUP1Owr Urticaria Activity Score (uas7): https://www.mdcalc.com/calc/10226/urticaria-activity-score-uas More information about XOlair: https://www.xolair.com/chronic-spontaneous-urticaria.html

La iniciativa AMAX4, según su sitio web amax4.org, está dedicada a reducir y prevenir las muertes innecesarias relacionadas a la anafilaxis asma. La iniciativa fue lanzada en el 2022, luego de la trágica muerte del hijo del Dr. Ben y Tamara McKenzie, Max, quien murió a los 15 años de edad debido a una lesión hipóxica cerebral sufrida luego de broncoespasmo y asma por anafilaxis inducida por comida.   El poder de las historias Las historias tienen el poder de crear un contexto y un "por qué". Las historias pueden ayudarnos no solamente a recordar el mensaje, sino también a entender cómo aplicarlo o ejecutarlo. Esta es la razón por la cual muchos capítulos de textos de medicina y cursos de emergencias comienzan con una historia. La campaña AMAX4 enseña el manejo de anafilaxis y está basada en la historia de la muerte súbita por anafilaxis de Max McKenzie... esta es su historia. La historia de Max McKenzie https://youtu.be/OkSy8HYRL-I Este es su papá, el Dr. McKenzie contando su historia... https://youtu.be/JIHglT_MiGA Historia previa de asma Ninguna vez admitido a la UCI Alérgico a nueces, cargaba auto-inyector de adrenalina Comió nueces por error... Urticaria, vómito y dificultad para respirar Se auto-administró epinefrina y albuterol Cronología de eventos Lista de errores en el manejo están en la conferencia. No es necesario discutir los errores sino enfocarnos en cómo hacer lo correcto. Sin embargo, algunos (quizás muchos de los errores) no fueron manejos incorrectos sino fallas en manejar oportuna y agresivamente lo que desde un principio sabían que estaba ocurriendo. Sensación de muerte inminente: "Creo que me voy a morir". Al principio Max lució como cualquier otro paciente... estaba hablando en oraciones completas. Pero rápidamente se deterioró. Max tenía un historial previo de anafilaxis. Él sabía lo que se siente tener alergias severas, y sabía lo que es anafilaxis. Lo que lo asustó fue la velocidad de la reacción. Las banderas rojas son signos y síntomas que nos deben alertar de que una situación está escalando y que nuestro nivel de agresividad debe escalar también. El balance entre el sentido de proveer calma y dominar la situación no son mutuamente excluyentes. Definición de anafilaxis No es una reacción alérgica severa, es anafilaxis. Conceptualmente, es importante recordar que la alergia es un mecanismo de defensa. La anafilaxis ocurre cuando el cuerpo no puede modular esta respuesta y ahora la propia respuesta es la que amenaza la vida del paciente. Según la World Allergy Organization, la definición de anafilaxis es: Opción 1: alergeno conocido con broncoespasmo o hipotensión Inicio súbito (minutos a horas) de síntomas laríngeos, broncoespasmo o hipotensión luego de la exposición a un alergeno conocido o altamente probable para ese paciente aún en ausencia de síntomas en la piel. Opción 2: alergeno desconocido con piel + (disnea, shock, o GI) Inicio súbito (minutos a horas) de enfermedad con envolvimiento simultáneo de la piel, mucosa (o ambas) Y AL MENOS UNO DE LOS SIGUIENTES: Compromiso respiratorio: disnea, broncoespasmo, estridor o hipoxemia) Hipotensión o signos asociados a pobre perfusión (hipotrofia, síncope, incontinencia) ​Signos gastrointestinales severos: calambres abdominales, vómitos repetitivos, especialmente luego de exposición a alergenos alimentarios. https://youtu.be/m4OeMj-19wo ¿Por qué ocurre el paro cardiaco en el paciente con anafilaxis? Hipoxia - no se puede ventilar por obstrucción de la vía aérea Hipotensión - no hay perfusión a órganos importantes La epinefrina (adrenalina) ayuda a tratar ambas causas. El daño cerebral puede ocurrir en 4 minutos. Asma y anafilaxis extrema En el manejo de la vía aérea y ventilación, la peor pesadilla es el escenario no-intubable y no-oxigenable. No significa que se tiene que morir, sino que hay que actuar inmediato con toda la agresividad posible en el manejo clínico del paciente. La inconsciencia por anafilaxis, debido a la hipoxia e hipotensión, indicó en este caso el momento de entender que esto es un caso de asma y/o anafilaxis extrema. Si supieras que tu paciente se va a morir pronto, ¿qué harías ahora? Existen casos de asma y anafilaxis… y existen casos de asma y anafilaxis. Un broncoespasmo puede ser fatal. Una persona puede morir por un ataque de asma.  En teoría, podemos revertir al paro cardiaco por hipoxia, pero eso no significa que el cerebro no va a haber sufrido un daño irreversible. Partiendo del tiempo teórico de 4 minutos para daño cerebral, el protocolo AMAX4 busca poder corregir la hipoxia en el menor tiempo posible enfocándose en 4 aspectos fundamentales: Adrenalina Relajante muscular Intubación rápida y efectiva Cuidado extremo   https://youtu.be/L78tf1idNZg Tiempo a la primera epinefrina Comentarlo o discutirlo es solamente el inicio de la preparación. No es suficiente "decirlo". Hay que físicamente practicarlo. ¿Qué tan rápido podemos hacerlo? ¿Cómo podemos mejorarlo? Hay formas que podemos optimizar el proceso. ¿Qué tiempo nos toma obtener un acceso vascular de emergencia? ¿Dónde tenemos el equipo de accesos vasculares de emergencia? ¿Qué tiempo nos toma poder administrar la primera dosis IV (IO?) de epinefrina? ¿Cómo calculamos la dosis del medicamento? ¿Dónde tenemos la epinefrina guardada? Kits de anafilaxis son un buen paso, pero no es suficiente tener el kit. Hay que practicar cómo se implementa, de lo contrario es un falso sentido de seguridad. Piensa en qué debemos tener para poder administrar adrenalina desde el área de triage. La epinefrina tiene varios efectos deseables: Inhibe la liberación de histamina Estimula receptores beta (corazón y pulmones) Estimula receptores alfa (vasos sanguíneos) No existe contraindicación a la adrenalina cuando se necesita. No existe dosis máxima de adrenalina. Existen efectos adversos a la epinefrina, especialmente cuando no se necesita. "La epinefrina es como un paracaídas." Funciona cuando se emplea en el momento oportuno, y es inútil luego que ya es demasiado tarde. Dosis de adrenalina Aunque los autoinyectores de adrenalina tienen una dosis estándar de adultos (0.3 mg o 300 mcg) y una dosis estándar pediátrica, no hay evidencia de que esta sea la dosis ideal para todas las situaciones. Se puede repetir el autoinyector cada 5 minutos hasta la resolución de los síntomas. Para entender el efecto de la adrenalina, es necesario entender dos cosas: los receptores y algo de matemática. Matemática básica 1 mg = 1,000 mcg 0.02 mcg/kg/min es lo mismo que decir 2 mcg/min en un paciente de 100 kg. 0.1 mcg/kg/min es lo mismo que 10 mcg/min en un paciente de 100 kg Es mejor aprenderse los medicamentos por kilo de peso para poder utilizarlos en pacientes de diferentes edades. Fisiología de receptores La adrenalina estimula los receptores: Beta - en dosis baja ( 0.1 mcg/kg/min, ejemplo 10 - ∞ mcg/min en adultos) Menciono la dosis por minuto porque, aunque es posible dar un bolo, es posible poner el paciente en infusión continua). También, menciono la dosis por kilogramo de peso porque así aplica a todos los pacientes indistintamente de su edad. Los receptores beta estimulan la frecuencia cardiaca y la broncodilatación (entre otras cosas), y los receptores alfa estimulan vasoconstricción en los vasos sanguíneos. IM versus IV La vía IM es sumamente conveniente porque es fácil y rápido, pero puede ser inútil si hay pobre perfusión periférica. Si la reacción progresa rápidamente, es posible que sea conveniente transicionar a la vía intravenosa, inclusive obviando completamente la vía intramuscular. La ruta IM puede ser útil cuando el paciente detecta los signos tempranos de anafilaxis y se autoinyecta la epinefrina. Sin embargo, Max recibió múltiples dosis IM sin efecto. Por lo tanto, es necesario saber cómo administrar la epinefrina por vía IV sin causar daño por administrar una dosis inapropiadamente alta. 0.01 mg/kg IM en infantes y niños La dosis recomendada de adrenalina en pediátricos es siempre 0.01 mg/kg IM o IV.  Sin embargo, la dosis de 0.15 mg puede ser muy alta en infantes que pesan menos de 15 kg o muy baja en los que pesen más. 0.3 mg/kg (300 mcg) IM versus 0.02 mcg/kg (2-10 mcg) IV? Este artículo de Grissinger en el 2017 cita que la administración de adrenalina utilizando autoinyectores puede evitar errores de cálculo de dosis, asociados a eventos adversos. No obstante, no hay evidencia para definir cuál es la dosis óptima... y situaciones extremas requieren medidas extremas. 0.3 mg/kg es la dosis IM, sin embargo una dosis IV de 0.02-0.10 mcg/kg puede estimular efectivamente los receptores beta sin causar vasoconstricción. Por ejemplo, las emergencias respiratorias son la causa principal de muerte en los pacientes pediátricos. Podemos bajar el umbral para decidir comenzar epinefrina como broncodilatador en un paciente que tiene un broncoespasmo severo. 0.01 mcg/kg (10 mcg) IV versus 1 mcg/kg (100 mcg) IV AMAX4 recomienda 1 mcg/kg cada 30 segundos, hasta 10 minutos o la dosis de paro cardiaco. Esto quiere decir que, a un adulto, le estaríamos administrando 100 mcg IV por dosis. Suena como una dosis alta, pero, veamos la circunstancia: un paciente inconsciente por anafiaxis o asma severa. En pocos minutos (o segundos) este paciente va a estar en paro cardiaco. No es irracional considerar que 100 mcg es una fracción de la dosis de 1000 mcg que pronto se le va a estar administrando cada 4 minutos (250 mcg/min si lo dividimos por 4 minutos). El punto que quiero establecer es que AMAX4 nos da una perspectiva de que el manejo agresivo de la anafilaxis no es darle 0.3 mg/kg de epinefrina IM, o darle 0.02-0.10 mcg/kg/min para estimular receptores beta. Por último No hay contraindicaciones a la epinefrina en anafilaxis.  Referencias Cardona V, Ansotegui IJ, Ebisawa M, El-Gamal Y, Fernandez Rivas M, Fineman S, Geller M, Gonzalez-Estrada A, Greenberger PA, Sanchez Borges M, Senna G, Sheikh A, Tanno LK, Thong BY, Turner PJ, Worm M. World allergy organization anaphylaxis guidance 2020. World Allergy Organ J. 2020 Oct 30;13(10) Grissinger M. EPINEPHrine for Anaphylaxis: Autoinjector or 1-mg Vial or Ampoule? P T. 2017 Dec;42(12):724-725. PMID: 29234208; PMCID: PMC5720482.

How do you know if your hives are chronic spontaneous urticaria?  Join Kortney and Dr. Payel Gupta in the second episode of this chronic spontaneous urticaria (CSU) series as they delve into the diagnostic journey of CSU.  Have you wondered if the path to a chronic spontaneous urticaria diagnosis is long? CSU can feel like a very complex disease to diagnose due to the lack of identifiable triggers, but this episode breaks down the steps healthcare professionals take to diagnose CSU.  Dr. G clarifies how allergists' and dermatologists' roles differ in diagnosing CSU. The episode emphasizes the importance of a detailed medical history and the tests involved in ruling out other conditions. It also describes the journey of determining CSU from other skin and allergic reactions through meticulous evaluation and specific testing methods. What we cover in our episode about diagnosing Chronic Spontaneous Urticaria: Introduction to CSU Diagnosis: CSU has no identifiable triggers, making diagnosis a process of elimination. Role of Specialists: Patients often start their diagnosis journey at urgent care, after which they consult allergists and dermatologists depending on the severity and symptoms of hives. Detailed Medical History: Essential questions cover medications, infections, travel history, and other health changes to rule out underlying causes. Physical Examination: Doctors check if hives are “blanchable” to differentiate from other conditions like vasculitis. Ruling out other Conditions: This involves evaluating other conditions in which hives are a symptom, such as mast cell disease or various autoimmune diseases.  Necessary Tests: Doctor's apprehension about doing a food allergy test unless necessary. Other tests include looking at blood count (CBC with differential) and inflammation (ESR or CRP).  More resources about chronic spontaneous urticaria:  Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/ What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticari This episode is produced in partnership with Allergy & Asthma Network. We want to thank Novartis for sponsoring this episode. Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Professor Marcus Maurer welcomes Dr Jörg Scheffel to discuss urticaria, including techniques used to interrogate mast cells and examine interstitial fluid, and a technique used to identify autoimmune-mediated forms of urticaria. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Chronic urticaria and the pathogenic role of mast cells; A novel approach for studying mast cell-driven disorders: Mast cells derived from induced pluripotent stem cells; Autoreactive IgE: Pathogenic role and therapeutic target in autoimmune diseases. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria' podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

Do you get hives and have no clue why? Then this episode is for you! Join Kortney and Dr. Gupta as they unpack chronic spontaneous urticaria (CSU) in a six-part series. You may also have heard of this condition called chronic idiopathic urticaria or spontaneous urticaria. In this first episode, Kortney and Dr. Gupta dive into the nitty gritty of chronic spontaneous urticaria. They define the medical term "urticaria," commonly known as hives, and discuss how CSU differs from other forms of urticaria. They dive into the symptoms, including the itchy and transient nature of hives, and emphasize that CSU can vary in appearance depending on skin tone.  What may seem complicated in chronic spontaneous urticaria is that there are no triggers. Instead, Dr. G walks us through the factors that may be culprits to CSU flares, such as stress and certain medications, and she highlights the impact of autoimmune conditions on CSU prevalence. What we cover in our episode about chronic spontaneous urticaria: Definition and symptoms of urticaria (hives) Differences between chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CINDU) The definition of chronic spontaneous urticaria and its symptoms The role of histamine in hives The mechanisms of itch and why scratching feels so good Factors that can exacerbate chronic spontaneous urticaria Populations most affected by chronic spontaneous urticaria The average duration of CSU symptoms Is chronic spontaneous urticaria curable More resources about chronic spontaneous urticaria: Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/ What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/ Episode 39: urticaria what causes hives? https://www.itchpodcast.com/episodes/39-urticaria This episode is produced in partnership with The Allergy & Asthma Network. We thank Novartis for sponsoring this episode and the series.  Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Episode 89 – Professor Elias Toubi joins Professor Marcus Maurer to discuss remission in urticaria, including its definition and possible risk factors for long disease duration.

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This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/FTH865. CME credit will be available until May 5, 2025.Chasing the Itch: Exploring the BTK Inhibitor Frontier In Chronic UrticariaThe University of Florida College of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.This activity is developed in collaboration with our educational partner, PVI, PeerView Institute for Medical Education.SupportThis activity is supported by an educational grant from Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/FTH865. CME credit will be available until May 5, 2025.Chasing the Itch: Exploring the BTK Inhibitor Frontier In Chronic UrticariaThe University of Florida College of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.This activity is developed in collaboration with our educational partner, PVI, PeerView Institute for Medical Education.SupportThis activity is supported by an educational grant from Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/FTH865. CME credit will be available until May 5, 2025.Chasing the Itch: Exploring the BTK Inhibitor Frontier In Chronic UrticariaThe University of Florida College of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.This activity is developed in collaboration with our educational partner, PVI, PeerView Institute for Medical Education.SupportThis activity is supported by an educational grant from Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

Associate Professor Elena Borzova joins Professor Marcus Maurer to discuss exercise as a trigger for urticaria in some athletes, including the paradoxical protective effect of exercise in people with urticaria. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Exercise-induced urticaria: A rare case report; and Physical activity and mental health among patients with atopic dermatitis or chronic spontaneous urticaria: A cross-sectional study. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria' podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/WQU865. CME credit will be available until May 6, 2025.BTK Inhibition Transforming the Landscape of Chronic Spontaneous Urticaria Treatment In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/WQU865. CME credit will be available until May 6, 2025.BTK Inhibition Transforming the Landscape of Chronic Spontaneous Urticaria Treatment In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/WQU865. CME credit will be available until May 6, 2025.BTK Inhibition Transforming the Landscape of Chronic Spontaneous Urticaria Treatment In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

Professor Marcus Maurer welcomes Dr Carolina Vera Ayala and Associate Professor Jonny Peter to discuss participation in clinical trials for urticaria, including patient concerns around placebo treatment. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: What is clinical research and why is it done?  Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria' podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

In this episode of Derms and Conditions, host James Q Del Rosso, DO, engages in a comprehensive discussion with Jason Hawkes, MD, MS, FAAD, a medical dermatologist in Rocklin, CA, on chronic spontaneous urticaria (CSU). They discuss CSU's position in the spectrum of urticarial conditions, explore differential diagnoses and treatment strategies, and offer a wealth of valuable insights into this complex disease. They begin by defining urticaria as a collection of conditions, explaining that this is often not well-delineated in textbooks or literature. Dr Hawkes categorizes urticaria into acute and chronic types, with chronic further divided into chronic inducible urticaria, which results from an identifiable trigger, and chronic spontaneous urticaria, which has no clear cause. They then explore differential diagnoses for CSU, including drug-induced urticarial reactions and conditions like mastocytosis or urticarial bullous pemphigoid that require thorough consideration. Transitioning to treatment strategies, they evaluate the use of systemic corticosteroids like prednisone for short-term relief in patients with CSU, taking into account reservations about long-term efficacy and potential side effects. Antihistamines are also highlighted for their rapid action, with Dr Hawkes encouraging prompt dosage adjustments if initial doses are ineffective. The conversation shifts to omalizumab, an injectable anti-IgE monoclonal antibody that has waned in popularity among dermatologists due to practical limitations and concerns over anaphylaxis risk. However, it is highlighted as a very effective treatment option for many patients with CSU, as it is amenable to office administration with low rates of anaphylaxis in real-world practice and has a broad consensus for use in guidelines. They conclude by touching on newer therapies in development that target alternative mechanisms, such as BTK and SYK inhibitors, which will broaden the therapeutic alternatives for patients with CSU. Tune into the full episode to gain a deeper understanding of CSU and glean invaluable insights into the nuances of this multifaceted condition.

If you've found it frustrating that no one can tell you why you have chronic urticaria hives (including chronic spontaneous urticaria, dermatographia, and even angioedema), I feel you.Especially when IgE allergies are ruled out (testing is negative) or even avoiding what you're allergic to isn't helpful. At that point, most doctors will say that there is no answer or clear trigger to what causes urticaria, basically leaving you with an increasing number of medications that may or may not help to control your skin.To say that this leaves many like you feeling enormously helpless and hopeless is an understatement.In my clinical practice, I've worked with many cases of chronic urticaria hives around the globe, helping to troubleshoot when doctors have all but given up in seeking an answer. Some cases have dated back decades, often having been seen at some of the most prestigious health institutions only to be told that there's nothing to be done beyond antihistamines (which have their own problematic side effects) and biologics like Xolair.I love helping people stop having hives and urticaria, especially since I get to explore the complex causes of chronic urticaria, which conventional medicine often ignores or assumes is impossible. So when new research starts pointing out connections to what I have seen in practice, I must share it!If you missed my previous article on hidden causes of chronic urticaria, check it out here! This will help you see that what this new paper demonstrates is highlighting a big missing link to chronic spontaneous urticaria, hives, and other histamine-driven issues.Before we dig into gut-chronic urticaria hives connection, I highly recommend that you download my Skin Rash Root Cause Finder. This is the exact method I've used with thousands of my private clients to help them discover what's really causing their rash (and yes, this works for hives, dermatographia and angioedema issues) >> Get the easy-to-use Skin Rash Root Cause Finder.In This Episode:Chronic urticaria (hives) gut causesProblems with urticaria treatment options (even Xolair)Gut imbalances noted in chronic spontaneous urticaria (hives)What are lipopolysaccharides + short-chain fatty acids (and why are they important)?Key findings from new research on gut-skin connection (specifically for hives)Quotes“The incidence of true histamine intolerance is much lower than you're led to believe and is based on old assumptions that need a serious update.”“Nearly 50% of those living with urticaria experience depression and anxiety (especially when the flare-ups are severe).”LinksGut microbiota facilitate chronic spontaneous urticariaHealthy Skin Show ep. 261: Chronic Hives: Why Aren't They Going AwayHealthy Skin Show ep. 265: Problem with Antihistamines That No One Tells You w/ Dr. Chris Thompson, MDHealthy Skin Show ep. 317: Itchy, Painful Rash From Thyroid Disease: Your Guide to Stopping ItHealthy Skin Show ep. 188: Histamine Intolerance + Skin Rashes (PART 1)

Dr Jason Hawkes joins Professor Marcus Maurer to discuss dermatologists' lack of urticaria knowledge, including tips on encouraging the US dermatology community to use resources such as the CRUSE app. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Key messages: Urticaria guidelines; Urticaria: A comprehensive review and Hives: Diagnosis and treatment. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria' podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

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Is it an allergy or an autoimmune vasculitis, or a little of both? Find out the story of urticarial vasculitis, how this disease was recognized and eventually sorted out from other types of urticaria. ·       Intro 0:12 ·       In this episode 0:21 ·       Case study 1:22 ·       Chronic spontaneous urticaria, hives and nettles 7:57 ·       Dermatographism and witchcraft? 10:15 ·       Causes of urticaria 11:17 ·       Theory of inflammation and histamines 11:40 ·       Urticaria and treatments with histamines 12:09 ·       Types of urticaria 13:02 ·       Mayo Clinic study 13:39 ·       Chronic urticaria as a manifestation of necrotizing venulitis 16:10 ·       Connection between types of urticaria and leukocytoclastic vasculitis 20:02 ·       More case studies 20:38 ·       What do we know about treatments? 22:23 ·       In conclusion 24:15 ·       Coming up in part two 25:08 ·       Thanks for listening 25:47 Disclosures: Brown reports no relevant financial disclosures. We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. References: Czarnetzki BM. Int J Dermatol. 1989;doi:10.1111/j.1365-4362.1989.tb01314.x. Kolkhir P, et al. J Allergy Clin Immunol. 2019;doi:10.1016/j.jaci.2018.09.007. McDuffie FC, et al. Mayo Clin Proc. 1973;48(5):340-8. Natbony SF, et al. J Allergy Clin Immunol. 1983;doi:10.1016/0091-6749(83)90096-9. Soter NA. N Engl J Med. 1977;doi:10.1056/NEJM197706232962505.