Podcast appearances and mentions of Henry T Greely

Henry Greely is Professor of Law at Stanford University and Professor by courtesy of Genetics, Stanford School of Medicine; Director, Center for Law and the Biosciences; Director, Stanford Program in Neuroscience and Society; and Chair, Steering Committee of the Center for Biomedical Ethics. *** Night White Skies is a program about our design futures as both the environment and our human bodies are now open for design. www.SeanLally.net Substack Instagram Thanks to Richard Devine for sample permission.

Ep 349 -   Let's Talk About CRISPR People Guest - Henry T. Greely   The science and ethics of editing human DNA went on high alert in November of 2018 when it was revealed that two babies had been born after their embryos were CRISPed. Professor Henry T. Greely, the Director of the Stanford Center for Law and the Biosciences, was notified and within minutes of the news, he was drawn into an ethical debate that we all must consider. Greely asks and attempts to answer the question, “Is it ethical to mess with human embryos?”    In his new book “CRISPR People,” he says, “Things are about to get interesting. This is an experiment that feels like a cross between bad fiction and reckless fiasco, shrouded in a deep fog of secrets.” The experiment in question took place in China by scientist He Jiankui, who attempted to edit the CCR-5, a gene known to be important in providing a gateway for HIV to infect some human cells.   Greely says, “The goal of the experiment was to make the gene inoperative and thus deprive HIV of that gateway for infection. The two edited embryos, of non-identical twin sisters, were transferred into their mother's uterus sometime in late March or early April 2018. Sometime in October, somewhere in China, they were born.” On the surface, a noble idea – the reality of the experiment is nothing short of an attempt to win the Nobel Prize.   Dr. He forged documents giving him permission to conduct the experiment and now he is in prison in China. His imprisonment has frustrated many who want to know more about his experiment, which appears to have been an exercise in his own aggrandizement.   Stuart McNish invited Henry Greely to join us for a Conversation That Matters about human germline editing. Please become a Patreon subscriber and support the production of this program, with a $1 pledge https://goo.gl/ypXyDs

What does the birth of babies whose embryos have gone through genome editing mean—for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences in CRISPR People: The Science and Ethics of Editing Humans (The MIT Press, 2021). Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices

What does the birth of babies whose embryos have gone through genome editing mean—for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences in CRISPR People: The Science and Ethics of Editing Humans (The MIT Press, 2021). Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm

What does the birth of babies whose embryos have gone through genome editing mean—for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences in CRISPR People: The Science and Ethics of Editing Humans (The MIT Press, 2021). Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm

What does the birth of babies whose embryos have gone through genome editing mean—for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences in CRISPR People: The Science and Ethics of Editing Humans (The MIT Press, 2021). Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm

What does the birth of babies whose embryos have gone through genome editing mean—for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences in CRISPR People: The Science and Ethics of Editing Humans (The MIT Press, 2021). Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm

What does the birth of babies whose embryos have gone through genome editing mean—for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences in CRISPR People: The Science and Ethics of Editing Humans (The MIT Press, 2021). Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/book-of-the-day

What does the birth of babies whose embryos have gone through genome editing mean—for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences in CRISPR People: The Science and Ethics of Editing Humans (The MIT Press, 2021). Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Music Industry Lawyer, Erin Jacobson , on music ownership. Tim Rademacher, Harvard University, on the tweeting tree. Winifred Phillips, composer of music for video games, and author of "A Composer’s Guide to Game Music." Author Marc Nobleman, “Bill the Boy Wonder: The Secret Co-Creator of Batman,” on feature in Hulu’s “Batman and Bill.” Henry T. Greely from Stanford University on the gene-edited CRISPR baby.

Bio  Henry T. Greely (@HankGreelyLSJU) is the Director of the Center for Law and the Biosciences; and Professor (by courtesy) of Genetics at the Stanford School of Medicine. He is also the Chair of Stanford's Steering Committee of the Center for Biomedical Ethics and the Director of Stanford's Program in Neuroscience and Society. Hank specializes in the ethical, legal, and social implications of new biomedical technologies, particularly those related to neuroscience, genetics, or stem cell research. He frequently serves as an advisor on California, national, and international policy issues. He is chair of California's Human Stem Cell Research Advisory Committee, a member of the Advisory Council of the NIH's National Institute for General Medical Sciences, a member of the Committee on Science, Technology, and Law of the National Academies, a member of the Neuroscience Forum of the Institute of Medicine, and served from 2007-2010 as co-director of the Law and Neuroscience Project, funded by the MacArthur Foundation. In 2007 Professor Greely was elected a fellow of the American Association for the Advancement of Science. Before joining the Stanford Law School faculty in 1985, Greely was a partner at Tuttle & Taylor, served as a staff assistant to the secretary of the U.S. Department of Energy, and as special assistant to the general counsel of the U.S. Department of Defense. He served as a law clerk to Justice Potter Stewart of the U.S. Supreme Court and to Judge John Minor Wisdom of the Court of Appeals for the Fifth Circuit. He received Stanford University's Richard W. Lyman Prize in 2013.  Resources Stanford University Center for Law and the Biosciences War & Peace by Leo Tolstoy News Roundup N.Y. Times: Data Firm with links to Trump Campaign Exploited Facebook User Data  The New York Times dropped a bombshell story on Sunday and it has sent Washington and the stock market into a tailspin. The Dow dropped more than 1%, or by over 300 points, Facebook lost some $37 billion in value, and Facebook CEO Mark Zuckerberg saw his net worth decline by $5 billion. In addition,  Congressional leaders including Dianne Feinstein, Amy Klobuchar, John Thune, Adam Schiff, Mark Warner and Chuck Grassley are just HAMMERING Facebook at this moment and I wouldn't want to be in Zukerberg's shoes right now. The New York Times investigation alleges that a London-based company called Cambridge Analytica, with deep ties to Republican donor Robert Mercer, who invested $15 million in Cambridge Analytica, Mercer's daughter who's on the board of Cambridge Analytica, and none other than Steve Bannon, who allegedly named the company, exploited Facebook user data to influence the 2016 presidential election to target users based on their psychographic profiles—things like religion, life statisfaction, conscientiousness, and extraversion. Of course, it's illegal under U.S. election laws to employ foreigners in political campaigns. So, The Times alleges, Cambridge set up a shell corporation and hired a Russian-American front man, Alexander Kogan, who was a researcher with the University of Cambridge. Kogan then created a Facebook personality quiz that paid users to share their private information and download the app. Some 50 million users were affected. This quiz allegedly scraped their information, and Cambridge Analytica gave him $800,000 for it. A former Cambridge Analytica employee, Christopher Wylie, was the whistleblower in all this. Facebook says it would suspend working with Cambridge Analytica and conduct an internal review, including the hiring of a forensics team. Channel 4 News London reported in an internal investigation that Cambridge Analytica uses bribes and sex workers to entrap politicians. This is just the surface. Summarizing every detail of this is way above my pay grade. But it's just layers upon layers of deception and bullshittery. You can find summaries and analysis in The New York Times, Washington Post, and The Wall Street Journal. Trump administration issues new Russian sanctions on same day it reveals attacks on power plants Russia has stepped its capability with regard to cyberattacks on nuclear power plans, water, and electric systems, according to U.S. intelligence officials.The country now has moved from having the ability to surveil American power plants to having the ability to disable them anytime tensions escalate, and in a similar manner with which it disabled power in the Ukraine on two separate occasions in 2015 and 2016. The accusations came on the same day the Trump administration imposed new economic sanctions against Russia for its role in hacking the 2016 presidential election. Sanctions include freezing assets and prohibiting business deals from being transacted with two-dozen Russian individuals and entities. Nicole Perlroth and David Sanger report in the New York Times and Jonathan Easley reports in The Hill. First pedestrian casualty for self-driving cars Ali Breland reports in the Hill that a 49-year-old woman was struck and killed by an Uber fully self-driving car while she was walking through a crosswalk in Tempe, Arizona on Monday. The state attracted Uber because of its deregulatory approach to self-driving vehicle technology. The National Transportation Safety Board announced that it would be investigating. Uber has suspended its testing of self-driving cars in Phoenix, Pittsburgh, San Francisco and Toronto. Walmart whistleblower sues after reporting e-commerce cheating A former Walmart executive has sued the world's largest retailer for firing him after he reported that the company was fudging its e-commerce results to show better numbers against Amazon. The complaint alleges that Walmart mislabeled products and deliberately failed to properly process returns in order to inflate sales numbers. Jonathan Stempel and Nandita Bose report in Reuters. Japanese regulators raid Amazon Ali Breland reports for the Hill that Japanese regulators raided Amazon last week. Japan's Fair Trade Commission may be concerned about Amazon's alleged practice of strong-arming suppliers to show cheaper prices on Amazon as compared to their competitors in Japan. Amazon recalls portable chargers  Amazon is recalling 260,000 AmazonBasics portable chargers after it received 53 complaints that they were overheating. One person reported being burned by the charger's battery acid. Four others reported fire and smoke. Kate Gibson reports for CBS. Google introduces wheelchair accessibility in Maps Google released Thursday a new wheelchair-friendly maps navigation feature. The feature will include accessible routes and information on accommodations in public transportation. Josh Delk reports in the Hill. Google bans Bitcoin ads  Google has decided to ban ads for Bitcoin and other cryptocurrencies. Facebook had previously initiated a similar ban. The company did not state why it decided to make the policy change. However, it comes as many in the policy community have expressed concern that online ads could be used to promote cryptocurrency scams. Daisuke Wakabayashi reports for The New York Times. Microsoft logs 200 discrimination, harassment complaints over 6 years Ali Breland reported in the Hill that, according to court filings filed by women suing Microsoft for gender pay and promotion discrimination, women working at the company lodged some 238 gender discrimination or harassment complaints between 2010 and 2016. Of the 118 that were gender discrimination complaints, Microsoft found only one to be “founded”. According to Natasha Bach at Fortune, Microsoft has changed the way it addresses harassment complaints by banning forced arbitration agreements. The question, of course, is whether that's enough. Conservative forms bogus company to lure tech workers Finally, Gizmodo reports that James O'Keefe—the undercover conservative activist— created a fake company and sent in employees of his Project Veritas organization to pose as recruiters. These fake recruiters then reached out to employees at major tech companies like Twitter to interview them and record their responses. In one case, an employee stated that Twitter hired few conservatives and secretly hid content posted by conservative users in a practice called “shadow banning”. Project Veritas then allegedly posted the videos as evidence of an anti-conservative bias at Twitter. Twitter has denied in Congressional testimony that it engages in shadow banning activities.

We spoke with Stanford Law professor Henry T. Greely about his new book The End of Sex, which predicts the end of procreational sex and the rise of designer babies in as early as 20 years.

What does sex have to do with human reproduction? Within the next 20 to 30 years or so, perhaps not much. At least that's how Henry T. Greely sees it. He's the Director of the Center for Law and Biosciences at Stanford University. He's also the author of a new book called The End of Sex and the Future of Human Reproduction. In this edition of Up Next, Greely talks about the coming revolution in reproduction, which, he says, will not only increasingly divorce sex from making babies, but also give parents more and more control over what genes their children will have. Series: "Up Next: Perspectives on the Future of Everything" [Health and Medicine] [Science] [Show ID: 30929]

What does sex have to do with human reproduction? Within the next 20 to 30 years or so, perhaps not much. At least that's how Henry T. Greely sees it. He's the Director of the Center for Law and Biosciences at Stanford University. He's also the author of a new book called The End of Sex and the Future of Human Reproduction. In this edition of Up Next, Greely talks about the coming revolution in reproduction, which, he says, will not only increasingly divorce sex from making babies, but also give parents more and more control over what genes their children will have. Series: "Up Next: Perspectives on the Future of Everything" [Health and Medicine] [Science] [Show ID: 30929]

Guest: Henry T. Greely, JD Host: Cathleen Margolin, PhD How might society best respond to the growing demand for cognitive-enhancing drugs by healthy individuals? That's the overriding question posed in a recent article published in Nature, written by a team of authors led by Henry Greely, professor of law and director of the Center for Law and the Biosciences at Stanford University. Mr. Greely joins host Dr. Cathleen Margolin to evaluate the appeal and the risks of drug-propelled cognitive enhancement, from safety considerations for healthy individuals using such medications, to the fairness of comparing the achievements of those who use versus those who do not, and the potential for coercion by superiors aiming, in theory, for enhanced performance from subordinates. One other question they will consider: is there a moral difference between cognitive enhancement through pharmaceuticals versus enhancement through sleep or nutritionally beneficial food products?