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The Deadcast examines how Franklin's Tower bucked every trend on Blues For Allah to become one of the Dead's all-time classics, including a tape of its studio creation, a look into the multi-tracks, & a rare line-by-line breakdown by lyricist Robert Hunter himself.Guests: David Lemieux, Geoff Gould, Jürgen Fauth, Shaugn O'Donnell, Chadwick Jenkins, Will Backstrom, Max Ritchie, Hannah GrabbensteinSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
The Center for Constitutional Rights has filed a lawsuit demanding records from the Trump administration about its funding of the Gaza Humanitarian Foundation (GHF), a private U.S. outfit coordinating with Israel and military contractors to distribute aid in Gaza. Since launching in May, GHF sites have become deadly flashpoints, with more than 1,400 Palestinians killed, over half at or near aid distribution points. On today's episode, we speak with Katherine Gallagher, senior attorney at CCR who says Israel's sidelining of the U.N.'s neutral aid system in favor of GHF's militarized model has turned food lines into “death traps,” as soldiers reportedly fired on starving Palestinians waiting for aid. — Subscribe to this podcast: https://plinkhq.com/i/1637968343?to=page Get in touch: lawanddisorder@kpfa.org Follow us on socials @LawAndDis: https://twitter.com/LawAndDis; https://www.instagram.com/lawanddis/ The post CCR Sues Trump Admin Over Gaza Aid Funding w/ Katherine Gallagher appeared first on KPFA.
Cum ar putea fi afectat Guvernul Bolojan de o decizie nefavorabila a CCR pe tema măsurilor fiscale (Adevărul) - Spionul dintre NATO și Rusia: România veriga slabă (DW) Contestare a politicii Guvernului Bolojan: „Mi-e teamă că România va pierde tot ce-a câştigat în ultimii ani” (HotNews) „Nu ştiu dacă aţi observat că cei care au susţinut politicile lui Traian Băsescu îl văd pe Ilie Bolojan drept un continuator fidel”, afirmă profesorul Cristian Pîrvulescu, decanul Facultăţii de Ştiinţe Politice de la SNSPA. El spune, într-un interviu pentru publicul HotNews, că România riscă să repete scenariile crizei din 2010, când ajustările bugetare brutale au generat costuri sociale şi au alimentat ascensiunea extremelor politice. „Nicio persoană raţională nu poate spune că nu e nevoie de reducerea cheltuielilor. Dar să nu confundăm reforma cu austeritatea”. „Această brutalitate trezeşte resentimente sociale. exact de asta n-avem noi nevoie acum, cu o Rusie în continuă ofensivă împotriva Occidentului şi cu o China care încearcă să profite de orice slăbiciune”. „Un guvern de extrema dreaptă va înseamna, de fapt, sfârşitul aventurii economice şi a bunăstării româneşti. Sunt convins de asta. Astfel, eu cred că guvernul trebuie să vadă acest semnal de alarmă, că nu se pot juca într-o democraţie cu sentimentele cetăţenilor”. Cum ar putea fi afectat Guvernul Bolojan de o decizie nefavorabila a CCR pe tema măsurilor fiscale (Adevărul) Toate cele cinci proiecte ale pachetului II de măsuri fiscal-bugetare asumate de Guvern în Parlament au ajuns pe masa judecătorilor constituționali. Eșecul la CCR al unuia dintre proiecte nu ar însemna și pierderea legitimității actualului Executiv, care este girată de majoritatea strânsă în Parlament de Coaliției, subliniază analiștii. De altfel, experiențele anterioare arată faptul că Executivul poate merge mai departe și poate reveni în Legislativ cu un nou proiect. „Nu cred că Curtea Constituțională va da un cec în alb pe tot ce înseamnă aceste proiecte” spune în dialogul cu ziarul Adevărul Radu Carp, profesor de drept. „Dacă vorbim despre pensiile magistraților, fiecare își dă seama că o decizie a Curții Constituționale care ar respinge proiectul de lege ar fi în favoarea pensiilor magistraților. Ar fi, așa cum s-au mai luat până acum, o decizie de castă, ca să zic așa. Dar aici nu trebuie să plătească Guvernul. Reformele care sunt vizate în aceste legi nu cred că încalcă principii Constituționale. Și nici adoptarea lor nu încalcă principii Constituționale. Așa încât, chiar și în cazul unor decizii nefavorabile, cred că nu este afectată legitimitatea guvernării, ea trebuie să continue atâta timp cât are o majoritate în Parlament și să încerce să reformeze sistemele din România, chiar dacă aceste sisteme pun o mare rezistență. (...) Legitimitatea guvernului provine din mandatul încredințat de Parlament în urma alegerilor”, explică redactorul șef Historia Ion M. Ioniță. „Legitimitatea oricărui Guvern pornește din Parlament”, punctează politologul Andrei Țăranu, amintind că există un precedent, din 2011, care ne arată că Executivul își poate continua misiunea. CCR va dezbate în 24 septembrie sesizările primite. Spionul dintre NATO și Rusia: România veriga slabă (DW) Fostul director adjunct al Serviciului de Informații din R. Moldova, Alexandru Bălan, a primit date sensibile din România și apoi le-a tranzacționat cu KGB Belarus. În mod ironic, spionul transnațional a fost prins la Timișoara unde urma să participe la o conferință cu titlul „Parcursul pro-european și provocările viitorului: alegerile parlamentare 2025 din R. Moldova”. Potrivit procurorilor care îl investighează „a fost angrenat în activități de divulgare neautorizată a unor informații secrete de stat, către reprezentați ai unei puteri străine, respectiv ofițeri din cadrul Comitetului Securității de Stat - KGB al Republicii Belarus, în condiții de natură să pună în pericol securitatea națională a României”. Anchetatorii au date din care rezultă că în 2024 și 2025 fostul șef al SIS Moldova a avut două întâlniri la Budapesta cu ofițeri de informații din Belarus și că „există suspiciuni rezonabile că au avut scopul de a transmite instrucțiuni și a face plăți pentru servicii prestate”. Jurnalista Sabina Fati consideră că rămâne complicat de explicat pentru oficialii români cum a ajuns Alexandru Bălan numărul 2 într-un serviciu secret străin să intre în posesia prețioaselor informații care țin de securitatea națională. A lucrat ca ofițer acoperit pentru vreunul din serviciile autohtone, a fost racolat de vreunul dintre ele și pe urmă a devenit spion dublu? Sau mai întâi l-au recrutat belarușii? Alexandru Bălan era un pion între NATO și Rusia alimentat (și de) România, iar prezența lui cu secretele țării în buzunar, pregătite pentru belaruși, nu face decât să scoată la iveală alte fisuri, de data aceasta din zona cea mai sensibilă a țării. În acest fel, România se vede tot mai vulnerabilă, cu oameni speciali gata oricând să lucreze de partea inamicului. Integral pe pagina DW.
In this episode of Nuggets On The Go, Melvin Lim and Yu Rong from PropertyLimBrothers explain the key drivers behind new launch pricing, buyer sentiment, and market trends in the Singapore real estate. They talk about how developers are adapting to the pressures of harmonisation policies, inflation, and shifting buyer behaviour, especially with interest rates falling and potential rate cuts ahead. Hear about absorption risk, layout effectiveness, and evolving pricing benchmarks across OCR, RCR, and CCR segments. They also discuss how property valuation influences national morale and the strategic frameworks investors can use to avoid overpaying or getting stuck with stagnant assets. Drawing on the MOAT Analysis and past market cycles, find out why some investors might benefit from cutting losses, while others should stick with a clear exit plan. If you're navigating pricing risk, developer tactics, or new launch timing, this episode provides essential insights to help guide your next move in the market. 00:00 Intro 01:22 Topics to cover 01:33 2025 New launch performance 04:05 Absorption on the ground 07:05 Harmonisation 08:50 Household Net Worth 10:48 Purchasing power in Singapore 18:44 Developer helping you to raise price 21:12 When new launch doesn't sell 24:40 Pivotal seasons 26:25 Developers with efficient layout 30:01 FED rate reduction policy 33:00 When price escalate too much 35:50 Waiting to take action (advice) 41:08 Preview of upcoming new launches / Artisan 8 / Penrith 42:18 Skye at Holland 44:00 Penrith 46:24 Launch price of Skye at Holland 48:35 Developer pricing 49:44 Canberra Crescent & Springleaf 55:53 Pricing for 2026 for New Launch 58:33 Closing 59:50 Outtakes
We talk with Dana at the DGLO about what the Climo brand is doing in Michigan. We also quickly recap CCR. Talk about the 2026 tour and how we feel about AI art. Hosted on Acast. See acast.com/privacy for more information.
This Morning, woman at Burning Man goes into labor, we see what's for sale in the Want Ads, and CCR's John Fogerty joins us and talks a little bit about re-recording some of our favorite Clearance Clearwater hits. Follow us on Facebook, Instagram and X. Listen to past episodes on 97Rock. Follow the Show on Apple, Spotify or Amazon MusicSee omnystudio.com/listener for privacy information.
The Deadcast uses Blues For Allah's complicated instrumental Slipknot! to explore the musical and creative ambiguity the Grateful Dead pursued in early 1975, when there both was and wasn't a Grateful Dead, & their public reemergence at Bill Graham's S.N.A.C.K. benefit that March.Guests: David Lemieux, Ned Lagin, Ron Rakow, Steve Brown, Gary Lambert, Joan Miller, Jay Kerley, Chadwick Jenkins, Shaugn O'Donnell, Melvin BackstromSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In the new episode of the Behind The Song podcast, Janda dives into the surprising inspiration behind Creedence Clearwater Revival's “Lookin' Out My Back Door.” Find out how one of CCR's most trippy tunes actually has a connection to a book by Dr. Seuss!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Musician/author Brad Cox joins Rich and Dan Bennett for a fast, funny deep-dive into how songs change meaning over time—from CCR and Springsteen to Sex Pistols and System of a Down—plus why some “big name” guests don't always drive podcast plays. They swap practical editing tips (Hindenburg, Descript, AI enhancers), talk Baltimore's scene (Turnstile, Infinity Knives), and share how to keep a show fresh without losing your mind. If you love music, making, or meaning, this one's packed. Sponsored by WHFC 91.1 FM Guests Bios: · Brad Cox — Maryland musician and songwriter, author of the series Children of the Program and a collected-lyrics book discussed on the show. He hosts/produces a live-format music podcast and continues to write, record, and perform across multiple projects. · Dan Bennett — Music obsessive and cultural commentator (and Rich's son) who highlights Baltimore artists and scenes, bringing sharp takes on punk, hardcore, and hip-hop throughout the episode. Main Topics: · How song meanings shift over time (CCR's “Fortunate Son,” Springsteen's “Born in the U.S.A.,” Sex Pistols' “God Save the Queen,” Stevie Nicks' “Edge of Seventeen”) · Music + politics: Tom Morello's “all music is political,” industry vs. indie perspectives · Practical podcast production: Hindenburg, Descript, AI audio enhancers, Opus Clip, multi-track pitfalls and echo fixes · Live-format recording challenges (multi-guest showcases, editing load) · Baltimore music scene: Turnstile, Trapped Under Ice, Infinity Knives & Brian Ennals; DIY ethos and crowd energy · Why unknown guests can outperform celebrities in downloads; getting beyond the “press-tour script” Resources mentioned: · Brad's Website: https://skitzocalypso.wixsite.com/bradwilliamcox· Episode Sponsor: Send us a textDonate HereWHFC 91.1 FMIt's all about community. WHFC 91.1 FM, Harford Community College Radio, is the college radio staDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showRate & Review on Apple Podcasts Follow the Conversations with Rich Bennett podcast on Social Media:Facebook – Conversations with Rich Bennett Facebook Group (Join the conversation) – Conversations with Rich Bennett podcast group | FacebookTwitter – Conversations with Rich Bennett Instagram – @conversationswithrichbennettTikTok – CWRB (@conversationsrichbennett) | TikTok Sponsors, Affiliates, and ways we pay the bills:Hosted on BuzzsproutSquadCast Subscribe by Email
Creedence Clearwater Revival's 1969 album Willy and the Poor Boys sounds like something out of 1965, or even 1865 - but definitely not the heavy, psychedelic late 1960s. But even though CCR's music feels like it's outside of time - or maybe because of it - it became the soundtrack of a generation. Ben, Amanda, and Rich make the case that Willy and the Poor Boys should be pulled down from the cultural wallpaper and appreciated as the fresh, crackling music it still is. Cohosts: Ben Marlin, Rich Bunnell, Amanda RodgersComplete show notes: https://discordpod.com/listen/165-creedence-clearwater-revival-willy-and-the-poor-boys-1969Discord & Rhyme's merch store: http://tee.pub/lic/discordpodSupport the podcast! https://www.patreon.com/discordpod
After getting the rights to his CCR catalogue back, John is releasing LEGACY THE CREEDENCE CLEARWATER REVIVAL YEARS. John called Bret to discuss keeping his voice excellent, his sons getting involved with the music, and, well, baseball!
Friday, August 15th, 2025Today, Governor Gavin Newsom announces a special election in California to fight back against Republican gerrymandering in Texas; a DC man who threw a sandwich at law enforcement was a Department of Justice employee; an inspector general report finds severe shortages at VA hospitals; Kari Lake defends her Voice of America cuts as lawmakers warn her she overstepped; the Fifth Circuit Court of Appeals sides with Black Louisianians by striking down their racists state legislative map; Trump announces his Kennedy Center Honorees and says he might include himself among them; and Allison and Dana read your Good News.Thank You, IQBARText DAILYBEANS to 64000 to get 20% off all IQBAR products, plus FREE shipping. Message and data rates may apply. Guest: John FugelsangTell Me Everything - John Fugelsang, The John Fugelsang PodcastJohn Fugelsang - Substack@johnfugelsang.bsky.social - Bluesky, @JohnFugelsang -TwitterSeparation of Church and Hate by John Fugelsang - Pre-order StoriesCalifornia will move forward with redistricting vote to counter Texas, Newsom says | ABC NewsTrump leaves his mark on the Kennedy Center Honors | POLITICO‘Severe' staff shortages at US veterans' hospitals, watchdog finds | Trump administration | The GuardianKari Lake defends VOA cuts in court after warnings from Capitol Hill | The Washington PostFifth Circuit Sides with Black Louisianians, Strikes Down Racially Discriminatory State Legislative Map | American Civil Liberties UnionFired DOJ employee could face prison for throwing sandwich at officers | The Washington PostGood Trouble “I just received an email from the Center for Reproductive Rights saying that Trump's GSA cut off the connection that let visitors to their website send comments to regulations.gov. The CCR has been asking people to use that link to voice their opposition to the Trump administration's attempt to ban abortion care for veterans and their families, even in cases of rape, incest or medical emergencies. Wouldn't it be great if Beans listeners made up for the lost comments by sending thousands today?” Go to regulations.gov and search for Reproductive Health Services or use this link: regulations.gov/commenton/VA-2025-VHA-0073-0002 From The Good Newsregulations.gov/commenton/VA-2025-VHA-0073-0002Lessons from Cats for Surviving Fascism by Stewart Reynolds | Hachette Book GroupErika EvansReminder - you can see the pod pics if you become a Patron. The good news pics are at the bottom of the show notes of each Patreon episode! That's just one of the perks of subscribing! patreon.com/muellershewrote Our Donation LinksNational Security Counselors - DonateMSW Media, Blue Wave California Victory Fund | ActBlueWhistleblowerAid.org/beansFederal workers - feel free to email AG at fedoath@pm.me and let me know what you're going to do, or just vent. I'm always here to listen. Find Upcoming Actions 50501 Movement, No Kings.org, Indivisible.orgDr. Allison Gill - Substack, BlueSky , TikTok, IG, TwitterDana Goldberg - BlueSky, Twitter, IG, facebook, danagoldberg.comCheck out more from MSW Media - Shows - MSW Media, Cleanup On Aisle 45 pod, The Breakdown | SubstackShare your Good News or Good TroubleMSW Good News and Good TroubleHave some good news; a confession; or a correction to share?Good News & Confessions - The Daily Beanshttps://www.dailybeanspod.com/confessional/ Listener Survey:http://survey.podtrac.com/start-survey.aspx?pubid=BffJOlI7qQcF&ver=shortFollow the Podcast on Apple:The Daily Beans on Apple PodcastsWant to support the show and get it ad-free and early?The Daily Beans | SupercastThe Daily Beans & Mueller, She Wrote | PatreonThe Daily Beans | Apple Podcasts
LL Cool J Is Hosting the MTV VMAs 2025Pete Davidson says all the attention from the media about him having "big (d-word) energy" was embarrassing. Here he is on a recent podcast explaining.Sinéad O'Connor Biopic in Works James Gunn Addresses Margot Robbie's Future as Harley Quinn in New DC UniverseBilly Bob Thornton's 'Landman' Series Gets Season 2 Premiere Date on Paramount+Kevin Cronin Makes 'Heartbreaking' Decision on Touring FutureHere's something that may come as a surprise: Dora the Explorer turned 25 yesterday. Not 25 years old. The show originally debuted on Nickelodeon on back on August 14th, of 2000. What woman's name is featured most in song titles? That would be Mary. Here are four examples. (CCR, Tom Petty & the Heartbreakers, Kings of Leon, and Jimi Hendrix.)Vans brought on SZA as their new artistic director. She'll reimagine their upcoming marketing campaigns and help create new collections. The Most Ridiculous Things Fans Have Left Behind at FestivalsThe vibe at a concert depends on who you're seeing. You'll encounter very different crowds at a James Taylor show and a Gathering of the Juggalos . . . Someone on Reddit asked people who work at concert venues and festivals to name the weirdest things fans have left behind. Here are the highlights. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of NOTG, Melvin, Joan, and George from PropertyLimBrothers examine the URA Master Plan 2025 and its strategic implications across Singapore's evolving property zones. They break down critical updates in transformation areas like Bukit Timah's T City, Greater One-North, Newton-Patterson, and River Valley, while drawing tactical contrasts between 99-year leaseholds and freehold developments in CCR zones. They also discuss the role of MRT connectivity in redefining fringe area value, analyse how developers are using quantum play and harmonisation to compete, and share perspectives on how identity corridors may shape urban culture. The conversation looks closely at how planning for infrastructure, density, and amenities intersect with MOAT Analysis and pricing disparity frameworks to guide smarter property journeys. If you're planning your next move or evaluating long-term strategy, this episode offers grounded perspectives you won't want to miss. 00:00 Intro 01:28 URA Masterplan change 02:11 Identity Corridors 03:46 Inner Ring 04:40 George's father-in-law broke his hip 06:05 Bukit Timah Turf City 09:40 2025-2026 five year cycle 11:10 Favourite CCR new launch 15:33 3 classes of properties in CCR 18:50 Melvin's favourite BBQ restaurant is gone 19:20 Zyon Grand project 23:30 Rivergate one of the best projects 25:48 2030 Market in 99-year CCR projects 27:17 Hitting a new quantum 36:56 Greater One-North 37:39 Newton & Paterson 39:04 Defu 41:13 Bukit Timah Turf City 15K - 20K private & public homes 44:20 Bayshore Drive & Keppel Golf Course site 49:28 Bishan Town Centre 50:05 Mt Pleasant 50:59 Tiong Bahru MRT station 51:29 Riveria Punggol area 51:59 More residential sites at Kallang road 54:22 Tanjong Rhu & Guillemard Road 56:12 Pasir Ris 58:05 Telok Blangah 58:25 Haw Par Villa 58:40 Which area to buy? 1:01:40 Pearl's Hill 1:02:22 MRT line rankings 1:02:58 Changi Airport Terminal 5 1:03:39 New cycling bridges 1:04:15 URA exhibition 1:08:55 Final thoughts 1:12:32 Outtakes
The Grateful Deadcast points itself towards 1975 to begin a song-by-song celebration of Blues For Allah's 50th anniversary, loaded with raw session tapes, early lyric drafts, & the story of how the Dead built a new studio, musical language, batch of songs, & LP from the ground up. Guests: David Lemieux, Donna Jean Godchaux-MacKay, Ron Rakow, Stephen Barncard, Ned Lagin, Steve Brown, Gary Lambert, Keith Eaton, Shaugn O'Donnell, Chadwick Jenkins, Matt CampbellSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
email: rockpoprollpodcast@gmail.com website: www.rockpopandroll.com (Some of) My Favorite Covers: From the earliest days of rock and roll, cover songs have been a vital part of the music's forward movement, drawing on its past. Long before we knew about digital discovery, one of the fastest ways for new artists to connect with audiences was to reimagine an existing hit and put it on an album or 45—infusing it with their own style, energy, and attitude. A Chuck Berry riff might get filtered through the Beatles' harmonies, or an old blues song could get a new spin in the hands of the Rolling Stones. Musicians have always looked back to reinterpret the songs that shaped them, essentially creating a conversation across decades of music. Great rock and roll covers often redefine the song. Jimi Hendrix's “All Along the Watchtower” transformed Bob Dylan's stark folk ballad into a guitar-rock, psychedelic stomper. Aretha Franklin took Otis Redding's “Respect” and made it a soul-rock anthem of empowerment. Nirvana's raw take on David Bowie's "The Man Who Sold the World" introduced the track to an entirely new audience. In each case, the cover didn't just honor the original—it expanded its reach. The best covers don't just repeat the past—they rewrite it, proving that a great song can live many lives. 10 Iconic Rock and Roll Covers and How They Transformed the Original Jimi Hendrix – All Along the Watchtower (1968) Originally by Bob Dylan, Hendrix electrified the song with guitars and redefined it as a rock classic. Dylan himself later performed it in Hendrix's style. The Beatles – Twist and Shout (1963) Originally recorded by The Top Notes and popularized by The Isley Brothers, the Beatles turned it into their own via John Lennon's famously shredded vocal take. Aretha Franklin – Respect (1967) Originally by Otis Redding, Aretha flipped the perspective, injecting it with feminist firepower, gospel-inspired vocals, and made it an anthem for empowerment and equality. The Rolling Stones – Little Red Rooster (1964) Originally by Willie Dixon (recorded by Howlin' Wolf), the Stones slowed it down, leaning into the deep Chicago blues feel, introducing American blues to a younger audience. Nirvana – The Man Who Sold the World (1993) Originally by David Bowie, Nirvana's MTV Unplugged version stripped it to a haunting acoustic vibe that resonated with '90s alternative fans - and (re)introduced Bowie to them, Joe Cocker – With a Little Help from My Friends (1968) Originally by The Beatles, Cocker turned the Sgt. Pepper and Ringo song into a soulful, slow-burning rocker. Killer organ and gospel vocals. Janis Joplin – Piece of My Heart (1968) Originally by Erma Franklin, Joplin's version with Big Brother and the Holding Company was a raw and bluesy. The Clash – I Fought the Law (1979) Written in 1958 and first released in 1960 by The Crickets (after Buddy Holly left) and popularized by The Bobby Fuller Four, The Clash injected punk. It was their first single in the United States. Creedence Clearwater Revival – I Heard It Through the Grapevine (1970) Originally by Gladys Knight & The Pips and made famous by Marvin Gaye, CCR turned the Motown hit into an 11-minute swamp-rock jam. Jeff Buckley – Hallelujah (1994) Originally by Leonard Cohen, Buckley's haunting performance influenced artists in the decades that followed. Further Listening: 4 Lesser-Known but Brilliant Beatles Covers The Black Keys – She Said, She Said (2002) A gritty, stripped-down garage-rock take on The Beatles' psychedelic classic from Revolver. Siouxsie and the Banshees – Dear Prudence (1983) The Beatles' ballad morphs in goth-tinged new wave.. Gov't Mule – She Said, She Said / Tomorrow Never Knows (1998) A jam-band fusion of two Beatles tracks Fiona Apple – Across the Universe (1998) Slowed to a languid pace, Apple leans into the cosmic melancholy
The Grateful Deadcast visits the set for the Grateful Dead Movie, aka the Dead's five “retirement” shows at Winterland in 1974, with heads who attended. This bonus episode is a re-run of the 2nd half of Deadcast Season 9, episode 8.Guests: Donna Jean Godchaux-MacKay, Ron Rakow, Ned Lagin, David Grisman, , Steve Brown, Richie Pechner, Jerry Pompili, Jim Sullivan, Gary Lambert, Geoff Gould, Joan Brown, Michael Parrish, Corry Arnold, Strider Brown, Jay Kerley, Rita Fiedler, Rene Tinner, Lee Ranaldo, Gregory Barette, Ron Long, Brian AndersonSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Join us tonight as Andrew Del Mastro, special speaker with the missions "Faith Comes by Hearing" - a mission that we support here at CCR. This organization provides free Bible apps and MP3s to Audio Bible podcasts to people everywhere with free access to Gods Word. They offer hope to 6.1 billion people through Bible recordings in 1,243 languages.
A Motiva (MOTV3), antiga CCR, aposta na simplicidade operacional como vantagem estratégica em um setor marcado por alta regulação e grandes estruturas.Neste episódio, recebemos Flávia Godoy, Diretora de Relações com Investidores da Motiva, para entender como eficiência, foco regional e ativos previsíveis podem gerar valor ao investidor em 2025 — e além.O bate-papo conta também com a participação do analista Ricardo Bello.#MOTV3 #Motiva #Investimentos #RelaçõesComInvestidores
Ensalada de rock’n’roll con sabor a pantano. Brujas, caimanes e historias de las ciénagas moran en esta ecléctica selección de canciones.Playlist:(sintonía) MARTIN DENNY “Song of the bayou”JIM STAFFORD “Swamp witch”JOHN FOGERTY “Wicked old witch”CCR “Born on the bayou”THE NOMADS “Swamp girl”THE HANGMEN “Bayou moon”THE SCIENTISTS “Swampland”ROKY ERICKSON and THE ALIENS “Cold night for alligators”SCREAMIN’ WITCH DOCTORS “Witches in the swamp”MOONSHAKERS “El pantano”SCREAMIN’ JAY HAWKINS “Alligator wine”HIPBONE SLIM and MAMA ROSIN “Swamp water”BLOODSHOT BILL “Monsters in the bayou”KAY MARTIN “Swamp girl”LYNYRD SKYNYRD “Swamp music”LOS STRAITJACKETS “Swamp fire”Escuchar audio
It's hot! Damn hot! Especially here in the deep south of the USA, where we also add a layer of humidity for you to chew on. So, with that, the good Captain brings to you some swampy, creepy, backwater blues and southern gothic goodness that runs the gamut of rock n' punk n' metal! Go sit out on your front porch, grab your Sunday paper for fanning yourself, swat at those giant mosquitoes, and turn this episode up to 11. Get your swamp on!What is it that we do here at InObscuria? Well, we exhume obscure Rock n' Punk n' Metal in one of 3 categories: the Lost, the Forgotten, or the Should Have Beens. This episode covers all 3 genres and all 3 categories. You could say this is a well-rounded and slimy episode. As always, we hope that we turn you on to something new.Songs this week include:Moki Bone – “Falling” from Swamp Rock Religion (2019)Mister Earthbound – “The Great Silence” from The Great Silence (2022)Chickasaw Mudd Puppies – “Preacher” from Fall Line (2023)Wolf Twin – “Easy” from Live From The 5 Spot (2023)The Double Agents – “Friends In Low Places” from Friends In Low Places (2002)Daisy's Little Secret – “Bad Way” from Swamp Rock (2008)Wizened Tree – “Give The Rain” from Rock N Roll From Tocantins (2019)Please subscribe everywhere that you listen to podcasts!Visit us: https://inobscuria.com/https://www.facebook.com/InObscuriahttps://x.com/inobscuriahttps://www.instagram.com/inobscuria/Buy cool stuff with our logo on it!: https://www.redbubble.com/people/InObscuria?asc=uIf you'd like to check out Kevin's band THE SWEAR, take a listen on all streaming services or pick up a digital copy of their latest release here: https://theswear.bandcamp.com/If you want to hear Robert and Kevin's band from the late 90s – early 00s BIG JACK PNEUMATIC, check it out here: https://bigjackpnuematic.bandcamp.com/Check out Robert's amazing fire sculptures and metal workings here: http://flamewerx.com/
The Good Ol' Grateful Deadcast is thrilled beyond all audible frequencies to begin its 12th season by welcoming Dan Healy, the Grateful Dead's in-house sound wizard for most of their career, for tales from three decades in pursuit of high and higher fidelity.Guest: Dan HealySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Send us a textQuality childcare creates the foundation for lifelong learning and development, but finding the right program often leaves parents confused, frustrated, and uncertain. What should you actually look for beyond a clean facility and friendly staff? How do you know if a program will nurture your child's development in ways that matter?In this illuminating conversation, Dr. Lisa Hassler welcomes Judith Sikora, a respected voice in early childhood education with over three decades of leadership at national organizations like Child Care Aware of America. Sikora cuts through the confusion with practical wisdom that helps parents make informed choices based on what truly matters.We explore the crucial differences between licensing (minimum safety standards) and quality indicators, examining adult-to-child ratios, curriculum approaches, staff qualifications, and physical environments. Sikora explains why staff trained specifically in early childhood education rather than elementary education provide better experiences for young children—"it's like comparing elephants to apples"—and guides parents through evaluating center-based programs, family childcare homes, and friend/family care options based on their child's unique temperament and needs.Perhaps most surprisingly, Sikora challenges the common parental focus on academic readiness, revealing why communication skills and problem-solving abilities matter far more than memorizing letters and numbers at early ages. She offers specific questions to ask during program visits, observations to make about toys and activities, and explains how to access helpful resources like childcareaware.org's age-specific checklists.
The BiG Scuba Duo, Gemma and Ian chat to Barry McGill. Barry McGill is a deep wreck photographer and CCR instructor trainer with Indepth Technical. His main area of focus is exploration of deep-water shipwrecks around the Irish coastline, and he has been fortunate enough to discover and explore many significant previously undiscovered shipwrecks. Exploring iconic shipwrecks such as the R.M.S. Justicia, H.M.S. Audacious and R.M.S. Lusitania has left a significant impression on Barry, which helped develop his desire to discover and explore shipwrecks. Barry aims to share his passion for shipwreck exploration by capturing and sharing his images of many previously unphotographed shipwrecks including R.M.S. Amazon, H.M.S. Viknor and H.M.S. D6. Barry has also been part of many international shipwreck expeditions, most recently in September 2021 where he formed part of an international team of divers who undertook the first internal exploration of HMHS Britannic which lies in 120 m of water in the Kea Channel in Greece. This expedition was funded by the Explorers Club and aimed to document key internal elements of the ship which had never been accessed by divers previously. https://www.instagram.com/barrymcgill/ https://www.facebook.com/barry.mcgill.125 https://www.youtube.com/channel/UCbH2StdHWo0P-ARfjmxjPeQ https://indepthtechnical.ie/ The BiG Scuba Podcast is brought to you by Narked at 90. “Beyond Technical” If you are thinking of moving across to tech diving or completely new to diving, Narked at 90 can advise and guide on the best equipment and set up for your personal or commercial requirements https://www.narkedat90.com/?affiliate_code=p42PzCC8sx&referring_service=link We hope you have enjoyed this episode of The BiG Scuba Podcast. Please give us ★★★★★ review, and tell your friends and share and like, it all makes a difference. Contact Gemma and Ian with your messages, ideas and feedback via our media links or email thebigscubapodcast@gmail.com Take a look at the Insta3620 Store https://store.insta360.com/ and use our affiliate link BIGSUCBA We are on Instagram @thebigscuba We are on Facebook @thebigscuba We are in LinkedIn https://www.linkedin.com/in/ian%F0%9F%A6%88-last-325b101b7/ The BiG Scuba Website www.thebigscuba.com Amazon Store : https://www.amazon.co.uk/shop/thebigscuba Visit https://www.patreon.com/thebigscubapodcast and subscribe - Super quick and easy to do and it makes a massive difference. Thank you.
(00:00-21:34) Head Coach of the Tennessee Volunteers baseball team, Tony Vitello joins us on the phone lines. Good memories of Pearl Jam in St. Louis. Coach Vitello tells us what the Cardinals are getting in Liam Doyle. Doyle getting in shape and improving his velocity. SEC dominance in college baseball and the intimidating venues to play in. Building a culture in Knoxville. Tanner Franklin another Vol signing with the Cardinals. Great beard on that Coach Vitello.(21:42-34:01) Bangers. Never a bad time for some CCR. Welly gets his wish and Pestus from Festus is on the line. Pestus wants Pallante gone. Sonny Gray gone. Get rid of three catchers. Would you rather get hit in the face with a baseball or a hockey puck? Goalies not wearing masks.(34:11-55:38) Classic Francesa clip talking San Francisco Giants coming home to New York. Revisiting Francesa's reveiw of the Superman movie. Jackson's best asset is his ability to learn. Doug can't get past Grown Up 2. Chairman is trying to produce Movie Boy. Bob Barker's beauties. Welly's favorite cities in the Great Plains.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this week's episode, we are speaking with Tim Hofmann, a certified dog trainer working with the Cheetah Conservation Fund (CCF), running the Scat Detection Dog program. Since 2018, Tim has been leading the scat detection dog project for CCR where his expertise extends to field projects across Namibia and Angola, where he works with his dogs to detect and conserve rare wildlife species, like cheetahs and African wild dogs.Tim also holds a master's degree in Nature Conservation Biology and is currently pursuing a Ph.D. in wildlife sciences which very much comes into play with his work at CCF. Tim is passionate about innovative wildlife conservation approaches, and his work focuses on the intersection of dog training and conservation biology.What a dream to be out in some of the most beautiful landscapes in the world, with an amazing and sweet dog, all the while in support of wildlife conservation. And many of you will recognize CCF from a previous episode where we spoke with Dr. Laurie Marker-the Executive Director of the Cheetah Conservation Fund, titled The Cheetahs Longest Race.We are pretty sure you're gonna think this is one of the coolest jobs out there! What a dream job! Thanks so much to Tim and CCF and thanks for listening! Lots of Love. Time Stamps:Introduction: 00:16Interview: 6:46TA: 51:04Show Notes:https://cheetah.org/https://cheetah.org/ccf-blog/life-at-ccf/featured-staff-tim-hofmann/
We're back with a brand spankin' new edition of the Decibel Geek Times! Here's what Aaron's covering for us this time! Rockstar Deathdays: Remembering Jim Morrison, Arthur Kane, Jeff LaBar, and Gary Corbett. Album Anniversaries:Orchid's final EP Sign of the Witch turns 10. KoRn's back-to-basics KoRn III hits 15. Alice Cooper's Dirty Diamonds and Iommi/Hughes' Fused both turn 20.Mötley Crüe's New Tattoo hits 25, marking Randy Castillo's last album. Kyuss's final record turns 30, leading to QOTSA.35 years since Suicidal Tendencies broke through with Lights, Camera, Revolution! and Poison followed up with Flesh & Blood.AC/DC's Fly on the Wall and Lizzy Borden's debut both turn 40.UFO's Force It cover controversy happened 45 years ago.55 years since Funhouse by The Stooges, CCR's unstoppable Cosmo's Factory, and the heavy debut of Cactus. New Music:Wanted returns with Cutting Edge. Gods of Tomorrow unleash a shred-heavy debut. Laguna's Ghost of Katrina brings desert-fueled melodic rock. Madhouse delivers glam rock gold with Plead the 5th. Enuff Z'Nuff drop Xtra Cherries packed with guest appearances and rare cuts. It's all that and a lot more. We hope you enjoy the Decibel Geek Times for the week of 07.18.25 and SHARE with a friend! Decibel Geek is a proud member of the Pantheon Podcasts family. Contact Us! Rate, Review, and Subscribe in iTunes Join the Facebook Fan Page Follow on Twitter Follow on Instagram E-mail Us Subscribe to our Youtube channel! Support Us! Buy a T-Shirt! Donate to the show! Stream Us! Stitcher Radio Spreaker TuneIn Become a VIP Subscriber! Click HERE for more info! Comment Below Direct Download Learn more about your ad choices. Visit megaphone.fm/adchoices
We're back with a brand spankin' new edition of the Decibel Geek Times! Here's what Aaron's covering for us this time! Rockstar Deathdays: Remembering Jim Morrison, Arthur Kane, Jeff LaBar, and Gary Corbett. Album Anniversaries:Orchid's final EP Sign of the Witch turns 10. KoRn's back-to-basics KoRn III hits 15. Alice Cooper's Dirty Diamonds and Iommi/Hughes' Fused both turn 20.Mötley Crüe's New Tattoo hits 25, marking Randy Castillo's last album. Kyuss's final record turns 30, leading to QOTSA.35 years since Suicidal Tendencies broke through with Lights, Camera, Revolution! and Poison followed up with Flesh & Blood.AC/DC's Fly on the Wall and Lizzy Borden's debut both turn 40.UFO's Force It cover controversy happened 45 years ago.55 years since Funhouse by The Stooges, CCR's unstoppable Cosmo's Factory, and the heavy debut of Cactus. New Music:Wanted returns with Cutting Edge. Gods of Tomorrow unleash a shred-heavy debut. Laguna's Ghost of Katrina brings desert-fueled melodic rock. Madhouse delivers glam rock gold with Plead the 5th. Enuff Z'Nuff drop Xtra Cherries packed with guest appearances and rare cuts. It's all that and a lot more. We hope you enjoy the Decibel Geek Times for the week of 07.18.25 and SHARE with a friend! Decibel Geek is a proud member of the Pantheon Podcasts family. Contact Us! Rate, Review, and Subscribe in iTunes Join the Facebook Fan Page Follow on Twitter Follow on Instagram E-mail Us Subscribe to our Youtube channel! Support Us! Buy a T-Shirt! Donate to the show! Stream Us! Stitcher Radio Spreaker TuneIn Become a VIP Subscriber! Click HERE for more info! Comment Below Direct Download Learn more about your ad choices. Visit megaphone.fm/adchoices
Cum și-a început mandatul președintele Nicușor Dan / Alergător pe lângă minge (G4Media) - După doi ani și o criză majoră, Nicușor Dan are de luat o decizie grea. Diversiunea Cioloș la SRI (SpotMedia) Cum și-a început mandatul președintele Nicușor Dan / Alergător pe lângă minge (G4Media) Dezastruos ar fi cuvântul potrivit. În primele două luni după câștigarea alegerilor, președintele Nicușor Dan a arătat că nu dispune de suficientă forță pentru a-și impune voința politică, a comis cel puțin o eroare majoră și a demonstrat o capacitate limitată de înțelegere a mecanismelor statului, precum și zero instincte politice, scrie jurnalistul Dan Tăpălagă. Un șef de stat dispune de multă legitimitate și de o putere reală, dacă știe cum să le folosească. Când nu o face, tot sistemul îi miroase imediat neputința. Așa se face că, în justiție, nu i-a ieșit mai nimic: Inspecția Judiciară, Înalta Curte, judecătorul propus de PSD la CCR (Mihai Busuioc) — toți provin din tabăra anti-reformistă. Și toți au defilat nestingheriți pe sub nasul indiferent al președintelui Dan. Adăugați la acest tablou și catastrofa de negociere politică de la formarea guvernului, unde PSD a obținut cam tot ce și-a dorit — inclusiv Ministerul Justiției. Altfel spus, tot PSD va propune viitorii procurori-șefi ai DNA și Parchetului General, pe care Nicușor Dan ar dori să-i schimbe. Foarte bine, doar că tocmai le-a cedat PSD-ului puterea de a face noile numiri. Cel mai spectaculos autogol a fost atacarea la CCR a legii care înăsprește pedepsele pentru propaganda extremistă. Nicușor Dan a folosit, practic, aceleași argumente cu Călin Georgescu, George Simion, AUR și Diana Șoșoacă. Președintele mai are o ultimă șansă de reabilitare, odată cu numirea șefilor de servicii secrete, anunțată pentru toamnă. Integral pe pagina G4Media. După doi ani și o criză majoră, Nicușor Dan are de luat o decizie grea. Diversiunea Cioloș la SRI (SpotMedia) Numele lui Dacian Cioloș a fost vehiculat intens în ultimele săptămâni în spațiul public ca reprezentând alegerea lui Nicușor Dan pentru șefia SRI, dar nu a existat nicio discuție între cei doi pe această temă, conform unor surse Spotmedia.ro, speculațiile fiind extrem de asemănătoare cu cele dezvoltate în jurul numirii unui judecător CCR de către noul președinte. Oamenii politici din România au o legătură complicată și netransparentă cu serviciile de informații, iar compromisurile și lipsa de control civil asupra acestora au devenit critice pentru nivelul de încredere din societate în instituțiile statului. Liderii politici cred că raportul de forțe din coaliție depinde de cine va conduce SRI și SIE. Consultarea președintelui cu partidele nu va fi legată de nume, pentru că atributul nominalizării îi revine șefului statului, ci mai degrabă va fi legată de tatonarea șefilor de partide pentru obținerea unor reacții cu privire la votul din Parlament vizavi de o propunere sau alta. Profesorul universitar Andrei Țăranu, explică în exclusivitate pentru Spotmedia.ro puterea unui președinte și legătura cu serviciile secrete. O lege a serviciilor secrete ar trebui făcută de societatea civilă și experți independenți, spune expertul Toate încercările de modificarea a legislației de funcționare a serviciilor de informații s-au soldat cu eșecuri răsunătoare, în principal din cauza faptului că proiectele au fost realizate de oameni din interior sau de asociați ai acestora, fiind contestate puternic de opinia publică. Misiune Imposibilă: Dan și Bolojan și cele 24 de luni în care trebuie să salveze România de ea însăși (PressOne) Misiunea uriașă care le stă în față atât lui Nicușor Dan, cât și lui Ilie Bolojan: să convingă nu doar sute de politicieni obișnuiți cu hoția ca stil de viață prosper, ci și milioane de români obișnuiți să se descurce cum pot, deseori prin mici furtișaguri, doar ca să supraviețuiască. Dar cum poți face asta într-o țară în care toată lumea fură? Cum poți vorbi despre dreptate socială când magistrații - tocmai cei care se presupune că ar trebui să facă dreptate - și-au făcut stat în stat și se ceartă cu premierul pe media de vârstă la care binevoiesc să iasă la pensie - că o fi 52 de ani, iar nu 48, cum spune Bolojan? Cum poți repara relația cu acest popor care a votat la două mâini cu PSD și populiștii timp de 35 de ani, dar care a avut pretenția ca răspunderea pentru populism să și-o asume altcineva? În fine, cum poți lupta în răspăr cu un popor mânios și care respinge exact singurele surse de bunăstare care pot ține România în viață în următorii ani - fondurile și valorile europene? Jurnalistul PressOne Adrian Mihălțianu remarcă faptul că s-a acordat o atenție sporită nedreptăților pe care le fac bugetarii (cu mic, cu mare, la grămadă) și privații (mai ales companiile alea mari și străine, care nu-și păstrează, domnule, profiturile în țară), și o atenție foarte scăzută pușculiței de bani a partidelor și a rețelelor lor mafiote din teritoriu: celebrul PNDL / Anghel Saligny, programul din care se hrănesc miile de primari din teritoriu și mai ales baronii locali care au definit aceste partide în ultimii 30 de ani. Înțeleg că domnul Bolojan nu poate isteriza din prima clientela politică PNL și PSD și că trebuie să-și pregătească atent următorii pași dacă vrea să rămână la guvernare suficient timp cât să urnească lucrurile, însă absența acestui program extrem de dăunător stabilității economice a României din prim-planul discuțiilor publice nu e un semn bun, mai notează editorialistul. În opinia sa, România poate scădea foarte rapid o bună parte din deficitul său bugetar dacă reorientează integral fondurile rămase necontractate din Anghel Saligny către finanțări proprii în proiecte europene.
Primul pachet de masuri fiscale adoptat de Guvern continua sa aiba ecouri. Salariaţi din mai multe instituţii au protestat în Piaţa Victoriei, faţă de măsurile fiscale din primul pachet, despre care afirmă că ”afectează grav capacitatea de administrare a fondurilor europene”. Pe de alta parte, ministrul de resort, Dragoş Pîslaru, spune ca Bruxelles a confirmat că primul pachet adoptat de guvern şi al doilea, care urmează, rezolvă problema traiectoriei fiscale. AUR a atacat la CCR pachetul austerităţii, apreciind că este ”o lege toxică” şi reprezintă un abuz de putere. Masurile sunt prevazute sa intre in vigoare la 1 august. Sunt reacţii la Moscova după anunţul lui Donald Trump că va da arme Ucrainei Kremlinul transmite ca va analiza declaratiile dar considera că Ucraina la va percepe ca pe un semnal de război. In plus, Rusia sustine ca este dispusa sa negocieze un acord cu Kievul. Presedintele american s-a aratat dezamagit de Rusia si a anunţat că Washingtonul a decis să continue transferul de arme şi echipamente militare către Kiev, dacă Europa va plăti pentru aceste livrări. Interviu RFI cu unul din sponsorii campaniei lui Nicușor Dan Numele celor care au sponsorizat cu sume importante în campania electorală a lui Nicușor Dan au fost făcute publice de actualul președinte. Printre acestea și un clujean, de etnie ucraineana, care a împrumutat echipa lui Dan, în două tranșe, corespunzătoare celor două tururi de scrutin, cu 800.000 de lei. Acum om de afaceri, el a explicat de ce s-a implicat în campania prezidentiala.
Război între magistrați și președintele României. Cine câștigă? (SpotMedia) - Despre extremism: de la Eminescu la Nicușor Dan (DW) Opriți jaful din companiile de stat! De ce Guvernul Bolojan trebuie să limiteze prin lege salariile și indemnizațiile nesimțite / Cum profiturile companiilor de stat sunt împărțite frățește între șefi și Consiliile de Administrație (G4Media) Guvernul Bolojan are datoria față de contribuabilii corecți – împovărați deja de măsuri de austeritate – să includă în al doilea pachet de reforme anunțat pentru sfârșitul lunii o regândire profundă a modului în care funcționează companiile de stat, scrie jrunalistul Dan Tăpălagă. G4Media.ro a documentat, în ultimele săptămâni, o serie de situații revoltătoare. În esență, vorbim despre jefuirea organizată a acestor companii prin: salarii uriașe, arbitrar crescute, care ajung la mii de euro pe lună bonusuri de zeci de mii de euro acordate fără criterii reale pensionări urmate de reangajări pe aceleași posturi indemnizații de Consilii de Administrație (CA) majorate de zeci de ori, cu aprobări formale și complicități la nivel înalt De regulă, aceste companii decid singure și arbitrar cum își cresc salariile și beneficiile, cu acordul formal – și adesea pasiv – al autorităților de supraveghere. Membrii CA și directorii se comportă ca niște vătafi pe moșia statului: nu răspund în fața nimănui și nu dau explicații pentru risipirea banului public. Da, legislație există. Dar ea este slabă, permisivă și plină de portițe. Iar aceste portițe trebuie închise urgent. Război între magistrați și președintele României. Cine câștigă? (SpotMedia) O decizie care indică mai degrabă teamă, a dus la declanșarea unui conflict între CSM și Palatul Cotroceni din cauza faptului că Nicușor Dan amână să semneze câteva cereri de pensionare venite din partea unor judecători. Magistrații, fără nicio susținere publică, criticați frecvent pentru pensiile speciale și corupția din sistemul de justiție, au ajuns din nou în centrul atenției în urma unor mașinațiuni suspectate ca ilegale prin care au impus-o pe judecătoarea Lia Savonea în fruntea Înaltei Curți de Casație și Justiție. Elena Costache, președinta CSM (Consiliul Superior al Magistraturii), printr-o mișcare surprinzătoare, a decis să-i scrie lui Nicușor Dan pentru a-i cere să semneze un număr de 22 de cereri de pensionare ale unor judecători. Mesajul șefei CSM este șocant prin faptul că dă lecții președintelui, ales de peste 6 milioane de cetățeni, dar și că sugerează o încălcare a legii de către acesta. Dacă CSM cu adevărat a constatat o încălcare a legii de către președintele României, trebuia să pună în discuție acest lucru pe ordinea de zi a Consiliului sau să facă plângere și să deschidă acțiuni în justiție. E fără precedent în istoria recentă a României ca un judecător să-l tragă de urechi pe șefului statului în afara cadrului creat de lege, consideră jurnalistul Emilian Isăilă pe pagina SpotMedia. Despre extremism: de la Eminescu la Nicușor Dan (DW) Președintele Nicușor Dan face o declarație politică atunci când atacă la Curtea Constituțională legea care înăsprește pedepsele pentru fascism, extremism, legionarism și rasism? Și de ce vrea să întoarcă legea din drum? Diana Șoșoacă, AUR și alți parlamentari populiști au făcut deja o contestație la CCR, iar Curtea a respins-o ieri, 10 iulie. Nicușor Dan argumentează în sesizarea trimisă judecătorilor constituționali neclaritatea definițiilor din lege și critică o posibilă restrângere a libertății de exprimare. Legea anterioară era suficient de puternică pentru a-i ajuta pe procurori și judecători să-i pedepsească pe nostalgicii legionari, pe fasciști și rasiști, doar că magistrații nu erau prea dornici să o pună în practică. Așa a scăpat, prezidențiabilul Călin Georgescu de pedeapsă, după ce procurorii l-au considerat nevinovat. De fapt, în ultimii cinci ani, procurorii au trimis în judecată cam o persoană pe an în baza acestei legi vechi de mai bine de 20 de ani. Președintele se întreabă dacă nu cumva ar putea fi pedepsit și Eminescu, poetul național și se teme ca nu cumva cărțile lui să fie cenzurate. Nicușor Dan se întreabă „până la ce nivel prezența unor idei și concepții fasciste, legionare, rasiste sau xenofobe” transformă un text „într-un material cu caracter fascist, legionar, rasist sau xenofob în sensul Legii”. „Claritatea este necesară”, se arată mai departe în documentul președinției, fiindcă sancționează penal distribuirea unor astfel de materiale. Specialiștii de la Cotroceni fac o confuzie intenționată între literatura de acum 150 de ani și propaganda xenofobă din prezent, mai scrie jurnalista Sabina Fati. Articolul integral pe pagina DW.
Revizurea indemnizațiilor din Consiliile de Administrație ale unor instituții precum Curtea de Conturi, Consiliul Concurenței sau Autoritatea de Supraveghere Financiară, reforma pensiilor speciale și reorganizarea instituțiilor din administrație sunt câteva dintre măsurile pregătite de Guvern pentru următoarele două pachete fiscale. Congresul liberal de maine va fi un bun punct de pornire pentru a masura sustinerea politica de care se mai buura premierul care spunea recent ca este cu mandatul pe masa. Nicuşor Dan a sesizat CCR pe Legea care vizează organizațiile cu caracter fascist, legionar, rasist sau xenofob Preşedintele susţine că termenii „legionar” şi „fascist” nu sunt explicaţi în mod clar. Seful statului mai spune că, prin comparaţie, in UE astfel de legi sunt mult mai clare. Solicitarea sefului statului este "îngrijorătoare", spune la RFI profesorul universitar Liviu Rotman, unul din cei mai cunoscuți istorici ai vieții evreiești din România. România are una dintre cele mai mici rate de testare voluntară pentru bolile cu transmitere sexuală din UE, în timp ce acestea sunt tot mai frecvente în rândul tinerilor Ce îi oprește să se testeze? Frica, rușinea, miturile și lipsa de informație. Pentru al doilea an consecutiv, tinerii care merg în această vară la Electric Castle și Summer Well se pot testa, gratuit, pentru BTS, în cadrul programului „Testat e Hot”, derulat de o rețea privată de sănătate.
John Fogerty has re-recorded many of his greatest CCR hits for a new album and he is telling the stories behind them! Here is the story behind Proud Mary!
It's hard to believe that CCR has been on the air for ten years and produced more than 200 episodes, so Alex sits down and thinks back on how CCR got started and some of the favourite episodes from the past. Including the mysterious Episode 0 and the far better Episode 1, which was recorded. Some good interviews, some of the more nerdy episodes, and the ones that certainly got CCR a tonne of attention. Plus a little bit of encouragement for those thinking of starting up a blog, podcast, or YouTube channel. CCR is ten years old this year, and to celebrate, we're hosting a Photowalk & Brewery Tour on 12 July starting at 11 am from the Great Lakes Brewpub at 11 Lower Jarvis in Toronto, Ontario. You can find more details on the event signup page on: Photowalk.me!
It's HardLore Summer and the sun is blazing, a little too much. It's too hot and it sucks.But you know what doesn't suck? These 20 records we're about to talk about.HAGS,Love, HardLore xoxoOFFICIAL COMPANION PLAYLIST: Spotify - https://open.spotify.com/playlist/3Vsxrp3imUDVD8wTHH88Ix?si=511319323b864b26 Apple Music - https://music.apple.com/us/playlist/hardlores-top-20-summer-albums/pl.u-4JommaDuJ03DPrAEdited by Steven Grise (@iamoneonenineseven) • Title sequence by Nicholas Marzluf (@marzluf)HardLore: A Knotfest SeriesJoin the HARDLORE PATREON to watch every single weekly episode early and ad-free, alongside exclusive monthly episodes: https://patreon.com/hardlorepodJoin the HARDLORE DISCORD: https://discord.gg/jA9rppggefCool links:HardLore Official Website/HardLore Records store: https://hardlorepod.comTry AG1 at DrinkAG1.com/HARDLORE to receive a free 1-year supply of vitamin D and 5 travel packs of AG1.Get 15% off MADD VINTAGE with code HARDLORE15! https://maddvintage.com/Get 20% OFF @manscaped + Free Shipping with promo code HARDLORE at MANSCAPED.com! #ad #manscapedpod FOLLOW HARDLORE:INSTAGRAM | https://www.instagram.com/hardlorepod/TWITTER | https://twitter.com/hardlorepodSPOTIFY | https://spoti.fi/3J1GIrpAPPLE | https://apple.co/3IKBss2 FOLLOW COLIN:INSTAGRAM | https://www.instagram.com/colinyovng/TWITTER | https://www.twitter.com/ColinYovng FOLLOW BO:INSTAGRAM | https://www.instagram.com/bosxe/TWITTER | https://www.twitter.com/bosxe#HARDLORE #HARDCORE 00:00:00 - Start00:00:41 - Introduction00:02:03 - New Found Glory - Sticks and Stones00:03:38 - Diamond - Don't Lose Your Cool00:05:54 - Cro-Mags - Best Wishes00:08:22 - Suicidal Tendencies - Self Titled00:10:21 - Warpaint - Self Titled00:11:58 - A$AP Ferg - Trap Lord00:14:32 - AFI - Shut Your Mouth and Open Your Eyes00:17:05 - The Mighty Mighty Bosstones - Let's Face It00:19:07 - Down - NOLA00:21:03 - Faith No More - The Real Thing00:23:27 - Fall Out Boy - From Under The Cork Tree00:25:39 - Rancid - ...Out Come The Wolves00:27:22 - Godflesh - Streetcleaner00:29:30 - Pardon This Interruption...00:32:36 - Bad Religion - No Control00:34:37 - Creedence Clearwater Revival - Best of00:36:52 - Lana Del Rey - Born To Die (Paradise Edition)00:39:31 - Saves The Day - Through Being Cool00:41:36 - Cave In - Antenna00:43:38 - Bo's #100:45:34 - Colin's #100:48:29 - Honorable Mentions
In this episode, CCR debates the issues!Follow:Zac Loughman @https://www.instagram.com/dr_crawdad/On FB https://www.facebook.com/profile.php?id=100011423011423Clint Bartley @IG: MetazoticsLLC FB: MetazoticsWebsite: metazotics.comPatreon:https://www.patreon.com/c/ColubridandColubroidRadio/Discord:http://discord.gg/ccradioExo-terrahttps://exo-terra.comhttps://linktr.ee/exoterrausaMPR NetworkFB: https://www.facebook.com/MoreliaPythonRadioIG: https://www.instagram.com/mpr_network/YouTube: https://www.youtube.com/channel/UCtrEaKcyN8KvC3pqaiYc0RQSwag store: https://teespring.com/stores/mprnetwork ★ Support this podcast on Patreon ★
Dr. Neeraj Agarwal and Dr. Jeanny Aragon-Ching discuss important advances in the treatment of prostate, bladder, and kidney cancers that were presented at the 2025 ASCO Annual Meeting. TRANSCRIPT Dr. Neeraj Agarwal: Hello, and welcome to the ASCO Daily News Podcast. I am Dr. Neeraj Agarwal, your guest host of the ASCO Daily News Podcast today. I am the director of the Genitourinary Oncology Program and a professor of medicine at the University of Utah Huntsman Cancer Institute and editor-in-chief of the ASCO Daily News. I am delighted to be joined by Dr. Jeanny Aragon-Ching, a GU medical oncologist and the clinical program director of the GU Center at the Inova Schar Cancer Institute in Virginia. Today, we will be discussing some key abstracts in GU oncology that were presented at the 2025 ASCO Annual Meeting. Our full disclosures are available in the transcript of this episode. Jeanny, it is great to have you on the podcast. Dr. Jeanny Aragon-Ching: Oh, thank you so much, Neeraj. Dr. Neeraj Agarwal: Jeanny, let's begin with some prostate cancer abstracts. Let's begin with Abstract 5017 titled, “Phase 1 study results of JNJ-78278343 (pasritamig) in metastatic castration-resistant prostate cancer.” Can you walk us through the design and the key findings of this first-in-human trial? Dr. Jeanny Aragon-Ching: Yeah, absolutely, Neeraj. So this study, presented by Dr. Capucine Baldini, introduces pasritamig, a first-in-class T-cell redirecting bispecific antibody that simultaneously binds KLK2 on prostate cancer cells and CD3 receptor complexes on T cells. KLK2 is also known as human kallikrein 2, which is selectively expressed in prostate tissue. And for reference, KLK3 is what we now know as the PSA, prostate-specific antigen, therefore making it an attractive and specific target for therapeutic engagement. Now, while this was an early, first-in-human, phase 1 study, it enrolled 174 heavily pretreated metastatic CRPC patients. So many were previously treated with ARPIs, taxanes, and radioligand therapy. So given the phase 1 nature of this study, the primary objective was to determine the safety and the RP2D, which is the recommended phase 2 dose. Secondary objectives included preliminary assessment of antitumor activity. So, pasritamig was generally well tolerated. There were no treatment-related deaths. Serious adverse events were rare. And in the RP2D safety cohort, where patients received the step-up dosing up to 300 mg of IV every 6 weeks, the most common treatment-related adverse events were low-grade infusion reactions. There was fatigue and grade 1 cytokine release syndrome, what we call CRS. And no cases of neurotoxicity, or what we call ICANS, the immune effector cell-associated neurotoxicity syndrome, reported. Importantly, the CRS occurred in just about 8.9% of patients. All were grade 1. No patients required tocilizumab or discontinued treatment due to adverse events. So, this suggests a favorable safety profile, allowing hopefully for outpatient administration without hospitalization, which will be very important when we're thinking about bispecifics moving forward. In terms of efficacy, pasritamig showed promising activity. About 42.4% of evaluable patients achieved a PSA50 response. Radiographic PFS was about 6.8 months. And among patients with measurable disease, the objective response rate was about 16.1% in those with lymph node or bone metastases, and about 3.7% in those with visceral disease, with a median duration of response of about 11.3 months. So, altogether, this data suggests that pasritamig may offer a well-tolerated and active new potential option for patients with metastatic CRPC. Again, as a reminder, with the caveat that this is still an early phase 1 study. Dr. Neeraj Agarwal: Thank you, Jeanny. These are promising results for a bispecific T-cell engager, pasritamig, in prostate cancer. I agree, the safety and durability observed here stand out, and this opens the door for further development, possibly even in earlier disease settings. So, shifting now from immunotherapy to the evolving role of genomics in prostate cancer. So let's discuss Abstract 5094, a real-world, retrospective analysis exploring the prognostic impact of homologous recombination repair gene mutations, especially BRCA1 and BRCA2 mutations, in metastatic hormone-sensitive prostate cancer. Can you tell us more about this abstract, Jeanny? Dr. Jeanny Aragon-Ching: Sure, Neeraj. So this study was presented by Dr. David Olmos, represents one of the largest real-world analyses we have evaluating the impact of homologous recombination repair, or what we would call HRR, alterations in metastatic hormone-sensitive prostate cancer. So, this cohort included 556 men who underwent paired germline and somatic testing. Now, about 30% of patients had HRR alterations, with about 12% harboring BRCA1 or BRCA2 mutations and 16% having alterations in other HRR genes. Importantly, patients were stratified via CHAARTED disease volume, and outcomes were examined across treatment approaches, including ADT alone, doublet therapy, and triplet therapy. The prevalence of BRCA and HRR alterations were about similar between the metastatic hormone-sensitive prostate cancer and the metastatic castrate-resistant prostate cancer, with no differences observed, actually, between the patients with high volume versus low volume disease. So, the key finding was that BRCA and HRR alterations were associated with poor clinical outcomes in metastatic hormone-sensitive prostate cancer. And notably, the impact of these alterations may actually be even greater in metastatic hormone-sensitive prostate cancer than previously reported in metastatic CRPC. So, the data showed that when BRCA mutations are present, the impact of the volume of disease is actually limited. So, poor outcomes were observed across the board for both high-volume and low-volume groups. So, the analysis showed that patients with HRR alterations had significantly worse outcomes compared to patients without HRR alterations. Median radiographic progression-free survival was about 20.5 months for the HRR-altered patients versus 30.6 months for the non-HRR patients, with a hazard ratio of 1.6. Median overall survival was 39 months for HRR-altered patients compared to 55.7 months for the non-HRR patients, with a hazard ratio of 1.5. Similar significant differences were observed when BRCA-mutant patients were compared with patients harboring non-BRCA HRR mutations. Overall, poor outcomes were independent of treatment of ARPI or taxanes. Dr. Neeraj Agarwal: Thank you, Jeanny. So, these data reinforce homologous recombination repair mutations as both a predictive and prognostic biomarker, not only in the mCRPC, but also in the metastatic hormone-sensitive setting as well. It also makes a strong case for incorporating genomic testing early in the disease course and not waiting until our patients have castration-resistant disease. Dr. Jeanny Aragon-Ching: Absolutely, Neeraj. And I think this really brings home the point and the lead up to the AMPLITUDE trial, which is LBA5006, a phase 3 trial that builds on this very concept of testing with a PARP inhibitor, niraparib, in the hormone-sensitive space. Can you tell us a little bit more about this abstract, Neeraj? Dr. Neeraj Agarwal: Sure. So, the AMPLITUDE trial, a phase 3 trial presented by Dr. Gerhardt Attard, enrolled 696 patients with metastatic hormone-sensitive prostate cancer and HRR gene alterations. 56% of these patients had BRCA1 and BRCA2 mutations. Patients were randomized to receive abiraterone with or without niraparib, a PARP inhibitor. The majority of patients, 78% of these patients, had high-volume metastatic hormone-sensitive prostate cancer, and 87% of these patients had de novo metastatic HSPC. And 16% of these patients received prior docetaxel, which was allowed in the clinical trial. So, with a median follow-up of nearly 31 months, radiographic progression-free survival was significantly prolonged with the niraparib plus abiraterone combination, and median was not reached in this arm, compared to abiraterone alone, which was 29.5 months, with a hazard ratio of 0.63, translating to a 37% reduction in risk of progression or death. This benefit was even more pronounced in the BRCA1 and BRCA2 subgroup, with a 48% reduction in risk of progression, with a hazard ratio of 0.52. Time to symptomatic progression also improved significantly across all patients, including patients with BRCA1, BRCA2, and HRR mutations. Although overall survival data remain immature, early trends favored the niraparib plus abiraterone combination. The safety profile was consistent with prior PARP inhibitor studies, with grade 3 or higher anemia and hypertension were more common but manageable. Treatment discontinuation due to adverse events remained low at 11%, suggesting that timely dose modifications when our patients experience grade 3 side effects may allow our patients to continue treatment without discontinuation. These findings support niraparib plus abiraterone as a potential new standard of care in our patients with metastatic hormone-sensitive prostate cancer with HRR alterations, and especially in those who had BRCA1 and BRCA2 mutations. Dr. Jeanny Aragon-Ching: Thank you, Neeraj. This trial is especially exciting because it brings PARP inhibitors earlier into the treatment paradigm. Dr. Neeraj Agarwal: Exactly. And it is exciting to see the effect of PARP inhibitors in the earlier setting. So Jeanny, now let's switch gears a bit to bladder cancer, which also saw several impactful studies. Could you tell us about Abstract 4502, an exploratory analysis from the EV-302 trial, which led to approval of enfortumab vedotin plus pembrolizumab for our patients with newly diagnosed metastatic bladder cancer? So here, the authors looked at the outcomes in patients who achieved a confirmed complete response with EV plus pembrolizumab. Dr. Jeanny Aragon-Ching: Sure, Neeraj. So, EV-302 demonstrated significant improvements in progression-free and overall survival for patients previously treated locally advanced or metastatic urothelial cancer, I'll just call it metastatic UC, as a frontline strategy, establishing EV, which is enfortumab vedotin, plus pembro, with pembrolizumab as standard of care in this setting. So, this year at ASCO, Dr Shilpa Gupta presented this exploratory responder analysis from the phase 3 EV-302 trial. Among 886 randomized patients, about 30.4% of patients, this is about 133, in the EV+P arm, and 14.5% of the patients in the chemotherapy arm, achieved a confirmed complete response. They call it the CCR rates. So for patients who achieved this, median PFS was not reached with EV+P compared to 26.9 months with chemotherapy, with a hazard ratio of 0.36, translating to a 64% reduction in the risk of progression. Overall survival was also improved. So the median OS was not reached in either arm, but the hazard ratio favored the EV+P at 0.37, translating to a 63% reduction in the risk of death. The median duration of complete response was not reached with EV+P compared to 15.2 months with chemotherapy. And among those patients who had confirmed CRs at 24 months, 78% of patients with the EV+P arm remained progression-free, and around 95% of the patients were alive, compared to 54% of patients who were progression-free and 86% alive of the patients in the chemotherapy arm. Safety among responders were also consistent with prior reports. Grade 3 or higher treatment-related adverse events occurred in 62% of EV+P responders and 72% of chemotherapy responders. Most adverse events were managed with dose modifications, and importantly, no treatment-related deaths were reported among those who were able to achieve complete response. So these findings further reinforce EV and pembro as the preferred first-line therapy for metastatic urothelial carcinoma, offering a higher likelihood of deep, durable responses with a fairly manageable safety profile. Dr. Neeraj Agarwal: Thank you for the great summary, Jeanny. These findings underscore the depth and durability of responses achievable with this combination and also suggest that achieving a response may be a surrogate for long-term benefit in patients with metastatic urothelial carcinoma. So now, let's move to Abstract 4503, an exploratory ctDNA analysis from the NIAGARA trial, which evaluated perioperative durvalumab, an immune checkpoint inhibitor, in muscle-invasive bladder cancer. So what can you tell us about this abstract? Dr. Jeanny Aragon-Ching: Absolutely, Neeraj. So, in NIAGARA, presented by Dr. Tom Powles, the addition of perioperative durvalumab to neoadjuvant chemotherapy, gem/cis, significantly improved event-free survival, overall survival, and pathologic complete response in patients with cisplatin-eligible muscle-invasive bladder cancer. Recall that this led to the U.S. FDA approval of this treatment regimen on March 28, 2025. So, a planned exploratory analysis evaluated the ctDNA dynamics and their association with clinical outcomes, which was the one presented recently at ASCO. So, the study found that the incidence of finding ctDNA positivity in these patients was about 57%. Following neoadjuvant treatment, this dropped to about 22%, with ctDNA clearance being more common in the durvalumab arm, about 41%, compared to the chemotherapy control arm of 31%. Notably, 97% of patients who remained ctDNA positive prior to surgery failed to achieve a pathologic CR. So, this indicates a strong association between ctDNA persistence and lack of tumor eradication. So, postoperatively, only about 9% of patients were ctDNA positive. So, importantly, durvalumab conferred an event-free survival benefit regardless of ctDNA status at both baseline and post-surgery. Among patients who were ctDNA positive at baseline, durvalumab led to a hazard ratio of 0.73 for EFS. So, this translates to a 27% reduction in the risk of disease recurrence, progression, or death compared to the control arm. In the post-surgical ctDNA-positive group, the disease-free survival was also improved with a hazard ratio of 0.49, translating to a 51% reduction in the risk of recurrence. So, these findings underscore the prognostic value of ctDNA and suggest that durvalumab provides clinical benefit irrespective of molecular residual disease status. So, the data also supports that ctDNA is a promising biomarker for future personalized strategies in the perioperative treatment of muscle-invasive bladder cancer. Dr. Neeraj Agarwal: Thank you, Jeanny. It is great to see that durvalumab is improving outcomes in these patients regardless of ctDNA status. However, based on these data, presence of ctDNA in our patients warrants a closer follow-up with imaging studies, because these patients with positive ctDNA seem to have a higher risk of recurrence. Dr. Jeanny Aragon-Ching: I agree, Neeraj. Let's round out the bladder cancer discussion with Abstract 4518, which reported the interim results of SURE-02, which is a phase 2 study evaluating neoadjuvant sacituzumab govitecan plus pembrolizumab in cisplatin-ineligible muscle-invasive bladder cancer. Can you tell us more about this abstract, Neeraj? Dr. Neeraj Agarwal: Sure, Jeanny. So, Dr Andrea Necchi presented interim results from the SURE-02 trial. This is a phase 2 study evaluating neoadjuvant sacituzumab govitecan plus pembrolizumab, followed by a response-adapted bladder-sparing treatment and adjuvant pembrolizumab in patients with muscle-invasive bladder cancer. So, in this interim analysis, 40 patients were treated and 31 patients were evaluable for efficacy. So, the clinical complete response rate was 38.7%. All patients achieving clinical complete response underwent bladder-sparing approach with a repeat TURBT instead of radical cystectomy. Additionally, 51.6% of patients achieved excellent pathologic response with a T stage of 1 or less after neoadjuvant therapy. The treatment was well tolerated, with only 12.9% of patients experiencing grade 3 or higher adverse events without needing dose reduction of sacituzumab. Molecular profiling, interestingly, showed that clinical complete response correlated with luminal and genomically unstable subtypes, while high stromal gene expression was associated with lack of response. These results suggest that sacituzumab plus pembrolizumab combination has promising activity in this setting, and tolerability, and along with other factors may potentially allow a bladder preservation approach in a substantial number of patients down the line. Dr. Jeanny Aragon-Ching: Yeah, agree with you, Neeraj. And the findings are very provocative and support completing the full trial enrollment and further exploration of this strategy in muscle-invasive bladder cancer in order to improve and provide further bladder-sparing strategies. Dr. Neeraj Agarwal: Agree. So, let's now turn to the kidney cancer, starting with Abstract 4505, the final overall analysis from CheckMate-214 trial, which evaluated nivolumab plus ipilimumab, so dual checkpoint inhibition strategy, versus sunitinib in our patients with metastatic clear cell renal cell carcinoma. Dr. Jeanny Aragon-Ching: Yeah, absolutely, Neeraj. So, the final 9-year analysis of the phase 3 CheckMate-214 trial confirms the long-term superiority of nivolumab and ipilimumab over sunitinib for first-line treatment of advanced metastatic renal cell carcinoma. So, this has a median follow-up of 9 years. Overall survival remains significantly improved with the combination. So, in the ITT patient population, the intention-to-treat, the hazard ratio for overall survival was 0.71. So, this translates to a 29% reduction in the risk of death. 31% of patients were alive at this 108-month follow-up compared to 20% only in those who got sunitinib. So, similar benefits were observed in the intermediate- and poor-risk groups with a hazard ratio of 0.69, and 30% versus 19% survival at 108 months. Importantly, a delayed benefit was also seen in those favorable-risk patients. So, the hazard ratio for overall survival improved from 1.45 in the initial report and now at 0.8 at 9 years follow-up, with 35% of patients alive at 108 months compared to 22% in those who got sunitinib. Progression-free survival also favored the nivo-ipi arm across all risk groups. At 96 months, the probability of remaining progression-free was about 23% compared to 9% in the sunitinib arm in the ITT patient population, 25% versus 9% in the intermediate- and poor-risk patients, and 13% compared to 11% in the favorable-risk patients. Importantly, at 96 months, 48% of patients in the nivo-ipi responders remained in response compared to just 19% in those who got sunitinib. And in the favorable-risk group, 36% of patients who responded remained in response, although data were not available for sunitinib in this subgroup. So, this data reinforces the use of nivolumab and ipilimumab as a durable and effective first-line effective strategy for standard of care across all risk groups for advanced renal cell carcinoma. Dr. Neeraj Agarwal: Thank you, Jeanny. And of course, since ipi-nivo data were presented, several other novel ICI-TKI combinations have emerged. And I'm really hoping to see very similar data with TKI-ICI combinations down the line. It is really important to note that we are not seeing any new safety signals with the ICI combinations or ICI-based therapies, which is very reassuring given the extended exposure. Dr. Jeanny Aragon-Ching: Absolutely agree with you there, Neeraj. Now, going on and moving on to Abstract 4514, which is the KEYNOTE-564 trial, and they reported on the 5-year outcomes of adjuvant pembrolizumab in clear cell RCC in patients who are at high risk for recurrence. Can you tell us a little bit more about this abstract, Neeraj? Dr. Neeraj Agarwal: Sure. So, the KEYNOTE-564 trial established pembrolizumab monotherapy as the first adjuvant regimen to significantly improve both disease-free survival and overall survival compared to placebo after surgery for patients with clear cell renal cell carcinoma. So, Dr Naomi Haas presented the 5-year update from this landmark trial. A total of 994 patients were randomized to receive either pembrolizumab or placebo. The median follow-up at the time of this analysis was approximately 70 months. Disease-free survival remained significantly improved with pembrolizumab. The median DFS was not reached with pembrolizumab compared to 68.3 months with placebo, with a hazard ratio of 0.71, translating to a 29% reduction in risk of recurrence. At 5 years, 60.9% of patients receiving pembrolizumab remained disease-free compared to 52.2% with placebo. Overall survival also favored pembrolizumab. The hazard ratio for OS was 0.66, translating to a 34% reduction in risk of death, with an estimated 5-year overall survival rate of 87.7% with pembrolizumab compared to 82.3% for placebo. Importantly, these benefits were consistent across all key subgroups, including patients with sarcomatoid features. In addition, no new serious treatment-related adverse events have been reported in the 3 years since treatment completion. So, these long-term data confirm pembrolizumab as a durable and effective standard adjuvant therapy for patients with resected, high-risk clear cell renal cell carcinoma. Dr. Jeanny Aragon-Ching: Thank you for that wonderful summary, Neeraj. Dr. Neeraj Agarwal: That wraps up our kidney cancer highlights. Any closing thoughts, Jeanny, before we conclude? Dr. Jeanny Aragon-Ching: It's been so wonderful reviewing these abstracts with you, Neeraj. So, the 2025 ASCO Annual Meeting showcased a lot of transformative data across GU cancers, from first-in-class bispecifics to long-term survival in RCC. And these findings are already shaping our clinical practices. Dr. Neeraj Agarwal: I agree. And we have covered a broad spectrum of innovations in GU cancers with strong clinical relevance. So, thank you, Jeanny, for joining me today and sharing your insights. And thank you to our listeners for joining us. You will find links to the abstracts discussed today in the transcript of this episode. If you find these conversations valuable, please take a moment to rate, review, and subscribe to the ASCO Daily News Podcast wherever you listen. Thank you so much. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Find out more about today's speakers: Dr. Neeraj Agarwal @neerajaiims Dr. Jeanny Aragon-Ching Follow ASCO on social media: @ASCO on Twitter ASCO on Bluesky ASCO on Facebook ASCO on LinkedIn Disclosures: Dr. Neeraj Agarwal: Consulting or Advisory Role: Pfizer, Bristol-Myers Squibb, AstraZeneca, Nektar, Lilly, Bayer, Pharmacyclics, Foundation Medicine, Astellas Pharma, Lilly, Exelixis, AstraZeneca, Pfizer, Merck, Novartis, Eisai, Seattle Genetics, EMD Serono, Janssen Oncology, AVEO, Calithera Biosciences, MEI Pharma, Genentech, Astellas Pharma, Foundation Medicine, and Gilead Sciences Research Funding (Institution): Bayer, Bristol-Myers Squibb, Takeda, Pfizer, Exelixis, Amgen, AstraZeneca, Calithera Biosciences, Celldex, Eisai, Genentech, Immunomedics, Janssen, Merck, Lilly, Nektar, ORIC Pharmaceuticals, Crispr Therapeutics, Arvinas Dr. Jeanny Aragon-Ching: Honoraria: Bristol-Myers Squibb, EMD Serono, Astellas Scientific and Medical Affairs Inc., Pfizer/EMD Serono Consulting or Advisory Role: Algeta/Bayer, Dendreon, AstraZeneca, Janssen Biotech, Sanofi, EMD Serono, MedImmune, Bayer, Merck, Seattle Genetics, Pfizer, Immunomedics, Amgen, AVEO, Pfizer/Myovant, Exelixis, Speakers' Bureau: Astellas Pharma, Janssen-Ortho, Bristol-Myers Squibb, Astellas/Seattle Genetics
In this episode, join us as we discuss CCR's first herping trip!Follow:Zac Loughman @https://www.instagram.com/dr_crawdad/On FB https://www.facebook.com/profile.php?id=100011423011423Clint Bartley @IG: MetazoticsLLC FB: MetazoticsWebsite: metazotics.comPatreon:https://www.patreon.com/c/ColubridandColubroidRadio/Discord:http://discord.gg/ccradioExo-terrahttps://exo-terra.comhttps://linktr.ee/exoterrausaMPR NetworkFB: https://www.facebook.com/MoreliaPythonRadioIG: https://www.instagram.com/mpr_network/YouTube: https://www.youtube.com/channel/UCtrEaKcyN8KvC3pqaiYc0RQSwag store: https://teespring.com/stores/mprnetwork ★ Support this podcast on Patreon ★
Enjoying the Ride: On TourThe Deadcast season finale hits shows at 3 legendary venues, exploring Dick Latvala's transformative experience at Red Rocks ‘79, Hollie Rose's tour journal, the wonders of the Alpine Valley parking lot, & when Shakedown Street got its name.Guests: David Lemieux, Jay Kerley, Hollie Rose, Rebecca Adams, Bill Lemke, Phil Garfinkel, Jim Jonze, Tom Ryan, Art Moss, Lisa Hitchcock, David Van Divier, Scott Bauer, Julie Dock, Mobile SteeleSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
(00:00-6:31) The Gibb brothers. DJ Pattycakes has some data points on NBA viewership in the YouTube Chat. Regular season viewership down across the board.(6:39-10:15) Any time you can play some CCR, it's worth it. The Athletic looking at teams that could shape the MLB trade deadline. Ryan Helsley. Have faith in John King.(10:25-18:26) E-Mail of the DaySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today, it's Sabrina Carpenter: Is her new video a Madonna reference? Kesha enjoys a banana split on stage… sort of. John Fogerty is re-recording “John's Versions” of classic CCR hits. Roommates can drive you crazy, but you can't strangle people. Game time: When did random stuff happen?
Livvy Dunne publicly wants her privacy, Corey Feldman strains to explain, Eli Zaret in studio, Silk Road's Ross Ulbricht's crypto speech, besties Tom Cruise & David Beckham ballwash each other, and a deep dive into the Sloopy Girl podcast. Is Jim Bentley a David Hall Financial bobblehead winner or loser? We discuss children allowances, and learn Eli was counting his coins with an abacus. Eli Zaret joins the program to discuss a little John Fogerty and CCR, the red-hot Detroit Tigers, another Honus Wagner baseball card record sale, the NBA Finals, Zion Williamson rape accusations, the Stanley Cup Finals, Travis Hunter duel-eligibility, NBA mock drafts, a male winning women's sports again… and again, WNBA hogwash and more. Corey Feldman did an impromptu interview with TMZ and is straining to do some explaining about his What's Eating Gilbert Grape and Titanic claims. This kid gets a bunch of money for having a job on graduation day. Emmanuel Macron gets the lip reading treatment. Brigitte Macron is not a dude, stop calling the Bonerline. Reminder that Tawana Brawley is a liar. The Imagine Dragons love Palestine. Convicted and pardoned Silk Road founder, Ross Ulbricht is back and doing speeches. He also received 300 Bitcoin ($31M). There was a terrorist attack in Boulder, Colorado. Greta Thunberg forgot about the climate. Goes full Hamas. Livvy Dunne claims she is being stalked and she's super bummed about it. Matthew Stafford sits in first class while his family sat in coach. Marc had a dance party this weekend. Lisa Leonard Dalton (Sloopy Girl) has a hell of a YouTube channel with crazy in-depth reporting. Farve Girl Jenn Sterger won't go away and is doing stand up comedy. Brooklyn Beckham and his wife are causing strife in the family. Great fathers Tom Cruise and David Beckham are besties. They ball washed each other during the UEFA Champion's League final. If you'd like to help support the show… consider subscribing to our YouTube Channel, Facebook, Instagram and Twitter (Drew Lane, Marc Fellhauer, Trudi Daniels, Jim Bentley and BranDon).
CCR has...thoughts about the Final Fantasy set. Thanks as always to Wave Sunray for our music! If you'd like to support the podcast, check out our patreon at patreon.com/mtggrindcast. Subscribers get swag and bonus content! And whether you subscribe or not, you're invited to join our discord, where we're building a community of friendly people all looking to improve at the game we love. Check it out here: https://discord.gg/Uq8x2RHYRU
As convidadas do programa Pânico dessa quarta-feira (28) são Madeleine Lacsko e Dani Freixo.Madeleine LacskoMadeleine Lacsko é jornalista, palestrante e consultora de risco reputacional. Atua como colunista em O Antagonista, Gazeta do Povo e UOL News. Apresenta o podcast PodFalar, sobre liberdade de expressão. É sócia da Gonew, edTech de lifelong learning.Faz parte do conselho do Instituto Monitor da Democracia e está fundando o Instituto Direito de Fala, pela Liberdade de Expressão. É autora do livro Cancelando o Cancelamento - como o identitarismo da militância tabajara ameaça a democracia.Trabalhou nas Rádios Trianon e Jovem Pan. Foi consultora do Unicef na erradicação da pólio em Angola, assessora do STF e da Alesp, diretora de comunicação da Change.org e assessora de marketing da CCR.Redes Sociais: Instagram: https://www.instagram.com/madeleinelacsko/X: https://x.com/madeleinelacskoYouTube: https://www.youtube.com/@podfalarmadeleinelacskoDani FreixoDaniella Freixo é psicóloga infantil com especialização em Psicologia Analítica de Jung e formação pela DEP em Transpessoal. Busca em seus conteúdos ensinar como é possível educar crianças com direção, acolhimento, responsabilidade, respeito e autonomia.Redes Sociais:Instagram: https://www.instagram.com/daniellafreixo/
The Deadcast cruises down the eastern seaboard, including stops in Hartford, Hampton, Philadelphia, and Landover, featuring touring tips, another police chase, & a visit to the White House.Guests: David Lemieux, Sam Cutler, Dennis Alpert, Tyler Roy-Hart, David Leopold, John Leopold, Rebecca Adams, Brian Schiff, Gary Lambert, Chris Goodspace, Winslow Colwell, Scott Jones, Chad EylerSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Conan is cracking us up, per usual. Sesame Street's future is in question. Is Nicole Kidman wearing a wig? Plus, the Diddy trial is continuing, and we aren't enjoying it. Kurt Cobain started in a CCR cover band, mosquitoes play favorites, and it's hard to imagine a time before the t-shirt. Would you sleep in a bed off the edge of a cliff?
The Deadcast makes a beeline for the northeast, focusing on shows from legendary venues in the Manhattan and Boston areas included on the new Enjoying the Ride box, including ESP experiments, weed smuggling, free jazz titans, multiple police chases, and more.Guests: David Lemieux, Ron Rakow, Sam Cutler, Richie Pechner, Allan Arkush, Ned Lagin, Gary Lambert, Blair Jackson, Stanley Krippner, Rebecca Adams, Johnny Dwork, John Scher, Michael Simmons, Tyler Roy-Hart, Henry K, Howie Levine, Kenny Schiff, Debbie RondeauSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Skywalking Through Neverland: A Star Wars / Disney Fan Podcast
Convention season is now in full swing. Next up - Comic Con Revolution (CCR)! Programming director David Nieves joins us to discuss what goes into putting on a pop culture convention. What were our first convention experiences? San Diego Comic Con was first for some, while others were relegated to a single banquet room at the local Sheraton Hotel (looking at you Richard). If you ever dreamed of working at a con, David gives tips on how you can make that happen. David tells us about a NEW feature for this year's CCR. Attendees will have an opportunity to experience a special pop up with Trapped Escape Room. In The Henchmen's Heist, you and your crew are aspiring villains! You join Madame Graffiti's band of art thieves. The mission? To steal as many pieces of art as possible from the world-famous Lumina Museum at their annual Spectrum Gala. Along with the many superstars and escape room, we will also be there with TWO of our Trivia party game shows. Sunday May 18th we will host our Pop Culture Trivia Challenge at 12pm. At 2:45 we will play our Star Wars Trivia Challenge Strikes Back! Today in Star Wars History 5/2/2006 Revenge of the Sith wins top honors in two categories at the 32nd Saturn Awards. The film wins ‘Best Science Fiction Film' and John Williams wins for ‘Best Score.' SPONSORS Small World Vacations is an official sponsor of Skywalking Through Neverland. Contact them for a no obligation price quote at www.smallworldvacations.com. Tell them Skywalking Through Neverland sent you. SUPPORT THE SHOW Find out how you can become a part of the Skywalking Force and unlock bonus content. CONTACT US Instagram: http://instagram.com/skywalkingpod Twitter: https://twitter.com/SkywalkingPod Facebook: https://www.facebook.com/skywalkingthroughneverland Send emails to share@skywalkingthroughneverland.com and follow us on Facebook. If you dug this episode, click over to iTunes | Stitcher | YouTube and leave us a review! Never Land on Alderaan!
The Deadcast's tour of Enjoying the Ride trucks all the way to the East Bay, exploring beloved venues including the Greek Theater & Kaiser Auditorium, with tales of the Hog Farm's Skeleton Crew & vintage field recordings from Oakland Coliseum Arena's parking lot. Guests: David Lemieux, Ron Rakow, Kevin Schmevin, Mark Pinkus, Blair Jackson, Steve Silberman, Rebecca Adams, David Gans, Johnny Dwork, Tyler Roy-Hart, Steven Bernstein, Robert Nyberg, Chad KroegerSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
The Deadcast begins our virtual tour of the new Enjoying the Ride box, visiting the cradle of the Dead in Palo Alto/Menlo Park (with a detour to visit the Warlocks' earliest shows) before heading to San Francisco with stops at the Fillmore West and Winterland.Guests: Connie Bonner Mosley, Ron Rakow, Ned Lagin, Ron Pietrowski, Tyler Roy-Hart, Les Earnest, Doug Oade, Eric Schwartz, Blair Jackson, Michael Parrish, Dominic Stefano, David LemieuxSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.