Podcasts about Genetic testing

Medical test

  • 1,175PODCASTS
  • 2,273EPISODES
  • 34mAVG DURATION
  • 5WEEKLY NEW EPISODES
  • Nov 20, 2025LATEST

POPULARITY

20172018201920202021202220232024

Categories



Best podcasts about Genetic testing

Show all podcasts related to genetic testing

Latest podcast episodes about Genetic testing

OffScrip with Matthew Zachary
Standard Deviation EP4: The Gamble

OffScrip with Matthew Zachary

Play Episode Listen Later Nov 20, 2025 11:13


Dr. Rachel Gatlin entered neuroscience with curiosity and optimism. Then came chaos. She started her PhD at the University of Utah in March 2020—right as the world shut down. Her lab barely existed. Her advisor was on leave. Her project focused on isolation stress in mice, and then every human on earth became her control group. Rachel fought through supply shortages, grant freezes, and the brutal postdoc job market that treats scientists like disposable parts. When her first offer vanished under a hiring freeze, she doubled down, rewrote her plan, and won her own NIH training grant. Her story is about survival in the most literal sense—how to keep your brain intact when the system built to train you keeps collapsing.RELATED LINKS• Dr. Rachel Gatlin on LinkedIn• Dr. Gatlin's Paper Preprint• Dr. Eric Nestler on Wikipedia• News Coverage: Class of 2025 – PhD Students Redefine PrioritiesFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Living Beyond 120
From Cycling to Paleo: A Journey to Optimal Health - Episode 311

Living Beyond 120

Play Episode Listen Later Nov 20, 2025 44:23


In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden and Trevor Connor delve into the intricacies of nutrition, particularly focusing on the Paleo diet, its principles, and its implications for health and longevity. Trevor shares his personal journey from professional cycling to studying nutrition, highlighting the importance of nutrient density and the role of glycemic load in dietary choices. They discuss the significance of the glycocalyx in vascular health, the impact of antioxidants on exercise adaptations, and the interplay between genetics and endurance training. The conversation emphasizes the necessity of balancing diet and exercise for optimal health. In this conversation, Dr. Jeffrey Gladden and Trevor Connor explore the intricate relationship between diet, exercise, and longevity, particularly focusing on the Paleo diet. They discuss common misconceptions about the diet, the importance of balance and variety in nutrition, and the role of metabolic pathways like AMPK and P53 in health. The conversation emphasizes the significance of genetic testing to tailor dietary choices and the need for a balanced approach to fueling during exercise. They conclude with resources for further learning about the Paleo diet and its benefits for health and longevity.    For Audience        Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ !    Takeaways         Trevor Connor transitioned from professional cycling to studying nutrition.         The Paleo diet emphasizes foods our ancestors evolved with.         Nutrient density is more important than macronutrient ratios.         Glycemic load is a key factor in dietary health.         The glycocalyx plays a crucial role in vascular health.         Antioxidants can hinder training adaptations if taken pre-exercise.         Genetics influence how individuals respond to endurance training.         Strength training may enhance antioxidant defenses more than endurance training.         A balanced approach to diet and exercise is essential for health.         You cannot out supplement a poor diet.  You can't run your way out of a bad diet.         A balanced approach to diet is crucial.         Biology operates on the principle of balance.         Variety in diet is essential for health.         Understanding metabolic pathways is key to longevity.         Genetic testing can guide dietary choices.         Fueling during exercise should be based on individual needs.         The sports nutrition world may promote unhealthy practices.         Natural foods are better for health than processed sugars.         Focus on overall health rather than just performance.   Chapters 00:00 Introduction to Longevity and Nutrition 02:59 Trevor's Journey into Paleo Diet 05:52 Understanding the Paleo Diet 09:02 Nutrient Density and Glycemic Load 12:01 The Role of Glycocalyx in Vascular Health 14:59 Antioxidants and Exercise Adaptations 17:57 Genetics and Endurance Training 20:51 Balancing Diet and Exercise for Optimal Health 23:12 The Balance of Diet and Exercise 24:51 Misconceptions of the Paleo Diet 27:38 Metabolic Flexibility and Variety in Diet 29:38 Understanding AMPK and P53 Pathways 32:23 The Importance of Genetic Testing 36:50 Fueling During Exercise: Myths and Realities To learn more about Trevor Connor/Paleo Diet:Facebook: https://www.facebook.com/RealPaleoDiet/ Instagram: https://www.instagram.com/realpaleodiet/ Email: info@thepaleodiet.com Website: thepaleodiet.com   Got a question for Dr. Gladden? Submit it using the link below and it might be answered in our next Q&A episode! https://form.typeform.com/to/tIyzUai7? Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw     Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options. Use of information from this podcast and any linked materials is at the listener's own risk. Podcast Guest Disclosures Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team. Sponsorships & Affiliate Disclosures To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes. We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented. Additional Note on Content Integrity All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.  

OffScrip with Matthew Zachary
Reenactments, Rants, and Really F*cked Up Insurance

OffScrip with Matthew Zachary

Play Episode Listen Later Nov 18, 2025 47:40


EPISODE DESCRIPTIONBefore she was raising millions to preserve fertility for cancer patients, Tracy Weiss was filming reenactments in her apartment for the Maury Povich Show using her grandmother's china. Her origin story includes Jerry Springer, cervical cancer, and a full-body allergic reaction to bullshit. Now, she's Executive Director of The Chick Mission, where she weaponizes sarcasm, spreadsheets, and the rage of every woman who's ever been told “you're fine” while actively bleeding out in a one-stall office bathroom.We get into all of it. The diagnosis. The misdiagnosis. The second opinion that saved her life. Why fertility preservation is still a luxury item. Why half of oncologists still don't mention it. And what it takes to turn permission to be pissed into a platform that actually pays for women's futures.This episode is blunt, hilarious, and very Jewish. There's chopped liver, Carrie Bradshaw slander, and more than one “fuck you” to the status quo. You've been warned.RELATED LINKSThe Chick MissionTracy Weiss on LinkedInFertility Preservation Interview (Dr. Aimee Podcast)Tracy's Story in Authority MagazineNBC DFW FeatureStork'd Podcast EpisodeNuDetroit ProfileChick Mission 2024 Gala RecapFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Raj Shamani - Figuring Out
Brain Power Secrets: Habits, Burnout, Sleep & Your Success Formula | Dr. Sajeev | FO434 Raj Shamani

Raj Shamani - Figuring Out

Play Episode Listen Later Nov 18, 2025 108:45


To explore more on Biohacking & Longevity: https://programs.sajeevnair.comTo know more about EPLIMO program using Genetic Testing: https://www.myeplimo.com/masterclassGuest Suggestion Form: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://forms.gle/bnaeY3FpoFU9ZjA47⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Disclaimer: This video is intended solely for educational purposes and opinions shared by the guest are his personal views. We do not intent to defame or harm any person/ brand/ product/ country/ profession mentioned in the video. Our goal is to provide information to help audience make informed choices. The media used in this video are solely for informational purposes and belongs to their respective owners.Order 'Build, Don't Talk' (in English) here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://amzn.eu/d/eCfijRu⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Order 'Build Don't Talk' (in Hindi) here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://amzn.eu/d/4wZISO0⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Our Whatsapp Channel: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.whatsapp.com/channel/0029VaokF5x0bIdi3Qn9ef2J⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe To Our Other YouTube Channels:-⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@rajshamaniclips⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@RajShamani.Shorts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Real Pink
Episode 359: How to rebuild energy & vitality after treatment ends

Real Pink

Play Episode Listen Later Nov 17, 2025 22:35


Breast cancer can be one of the toughest experiences anyone can face, but it can also be a transformative journey. While both the physical and emotional challenges are daunting, the path to healing offers a chance to rediscover resilience and joy in unexpected ways. Today, we are excited to welcome Aastha Saggar, a stage 3 breast cancer survivor and the founder of Still Strength Wellness, where she helps survivors, patients and caregivers reclaim peace, strength, and purpose. Aastha believes that rebuilding energy and vitality is not just possible but can be a beautiful new beginning. Get ready to be inspired as she shares her personal story, along with practical strategies that will empower our listeners to not only survive but thrive.

Connections with Evan Dawson
How could free genetic testing change medicine?

Connections with Evan Dawson

Play Episode Listen Later Nov 12, 2025 50:22


If you could find out that you are predisposed to certain health conditions — like cancer or heart disease — would you want to know? As reported by WXXI's Racquel Stephen, a new program at Rochester Regional Health offers no-cost genetic testing for people 18 and older. Our guests this hour discuss how it works and what it could mean for the future of personalized care in medicine. Our guests: Racquel Stephen, health, equity and community reporter at WXXI News Heather Bacchetta, MBA, ACRP-CP, director of precision medicine for Rochester Regional Health Prad Phatak, M.D., medical director of precision medicine for Rochester Regional Health and principal investigator for GenoWell ---Connections is supported by listeners like you. Head to our donation page to become a WXXI member today, support the show, and help us close the gap created by the rescission of federal funding.---Connections airs every weekday from noon-2 p.m. Join the conversation with questions or comments by phone at 1-844-295-TALK (8255) or 585-263-9994, email, Facebook or Twitter. Connections is also livestreamed on the WXXI News YouTube channel each day. You can watch live or access previous episodes here.---Do you have a story that needs to be shared? Pitch your story to Connections.

OffScrip with Matthew Zachary
Oy Vey! It's Libby Amber Shayo

OffScrip with Matthew Zachary

Play Episode Listen Later Nov 11, 2025 45:17


EPISODE DESCRIPTION:Libby Amber Shayo didn't just survive the pandemic—she branded it. Armed with a bun, a New York accent, and enough generational trauma to sell out a two-drink-minimum crowd, she turned her Jewish mom impressions into the viral sensation known as Sheryl Cohen. What started as one-off TikToks became a career in full technicolor: stand-up, sketch, podcasting, and Jewish community building.We covered everything. Jew camp lore. COVID courtship. Hannah Montana. Holocaust comedy. Dating app postmortems. And the raw, relentless grief that comes with being Jewish online in 2025. Libby's alter ego lets her say the quiet parts out loud, but the real Libby? She's got receipts, range, and a righteous sense of purpose.If you're burnt out on algorithm-friendly “influencers,” meet a creator who actually stands for something. She doesn't flinch. She doesn't filter. And she damn well earned her platform.This is the most Jewish episode I've ever recorded. And yes, there will be guilt.RELATED LINKSLibby's Website: https://libbyambershayo.comInstagram: https://www.instagram.com/libbyambershayoTikTok: https://www.tiktok.com/@libbyambershayoLinkedIn: https://www.linkedin.com/in/libby-walkerSchmuckboys Podcast: https://jewishjournal.com/podcasts/schmuckboysForbes Feature: Modern Mrs. Maisel Vibes https://www.forbes.com/sites/joshweissMedium Profile: https://medium.com/@libbyambershayoFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform.For guest suggestions or sponsorship, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Knew Method by Dr.E
Should I Get Genetic Testing? Geneticist Explains Why Your Genes Aren't Your Fate

The Knew Method by Dr.E

Play Episode Listen Later Nov 11, 2025 41:44


Should you get genetic testing? Evolutionary geneticist Dr. Melissa Ilardo says: probably not. What you believe about your genes affects your health outcomes more than what your genes actually say. That's not philosophy—that's what the research shows. On this episode of Medical Disruptors, I sit down with Dr. Ilardo to discuss why genetic determinism is a trap and why your genes aren't writing your health story the way you've been told. We discuss why knowing your genetic risks might actually harm you through the nocebo effect, and how to distinguish between genetic mutations you must know like BRCA versus ones you shouldn't check. We explore what epigenetics actually means for your daily health decisions and why family history of diabetes, heart disease, or Alzheimer's is not your fate. The conversation reveals how lifestyle changes gene expression faster than you think, and why meditation and environment reshape your biology in measurable ways. Your genes load the gun, but your environment decides whether it fires. And you have far more control over that trigger than genetic testing suggests. Looking to schedule a consultation with Dr. E? Book here: drefratlamandre.com/consult Check us out on social media: drefratlamandre.com/instagram drefratlamandre.com/facebook drefratlamandre.com/tiktok #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters [00:00:00] Why resilience, not disease [00:06:45] Thailand spark: sea nomads [00:12:40] Betting the PhD [00:20:45] Bigger spleens, oxygen edge [00:28:50] Epigenetics in plain English Guest Links: IG: @superhumanscilab Website: https://www.superhumanlab.org Learn more about your ad choices. Visit megaphone.fm/adchoices

Real Pink
Episode 358: Real Talk: Health Insurance Hang Ups

Real Pink

Play Episode Listen Later Nov 10, 2025 29:50


For many Americans, health insurance open enrollment is underway. They're deciding which coverage they need and how they can afford out-of-pocket expenses. They may be learning about high-deductible plans, health savings accounts, flexible spending accounts and so many other options when it comes to health insurance. So how do you know which plan is right for you? Joining me today is Valerie Nelson, manager of federal policy and advocacy at Susan G. Komen, and Mari Montesano, a manager at Komen's Breast Care Helpline, who assists individuals in need of information, support or help navigating their breast health issues.

Cancer Interviews
157: genetic testing helped stacy martin survive gastric cancer | prophylactic total gastrectomy

Cancer Interviews

Play Episode Listen Later Nov 9, 2025 27:10


Stacy Martin says genetic testing saved her life.   The testing indicated she had the CDH1 mutation.  The mutation gave her an 80 percent chance of getting gastric cancer and a 60 percent chance of breast cancer.  She opted for a prophylactic total gastrectomy to remove her stomach and addressed the possibility of breast cancer with a bilateral mastectomy.  Without a stomach, Stacy has had to change the way she eats, requiring food every two hours, and having to completely chew everything she eats.  Despite this live-changing surgery, Stacy is leading a healthy and happy life.   Unlike most people with cancer, Stacy's diagnosis was not preceded by symptoms.  Her mother had already been diagnosed with Stage IV uterin cancer.  That prompted Stacy and her siblings to undergo a genetic panel test.  It revealed Stacy had the CDH1 mutation, which meant she an 80 percent chance of getting gastric cancer and a 60 percent chance of breast cancer.    She had three options but chose to be proactive with a prophylactic total gastrectomy in 2019, a procedure that removed her stomach.  It was after the surgery that pathology revealed Stacy had gastric cancer in her removed stomach.    After successfully addressing the possibility of stomach cancer, she did the same with breast cancer with a bilateral mastectomy in 2020.   Stacy Martin said the toughest part of her cancer experience wasn't the treatment, but what she dealt with upon its completion.  She said she had to learn how to eat, and that without a stomach, she had to eat every two hours.  While she took snacks with her wherever she went, she had to alternate between snacks and something more substantial, making sure she got enough protein and carbohydrates.  Anything she ate had to be completely chewed because she no longer had the gastric juices in her stomach that break down food.  The only thing she can't eat are raw oysters because she says they are impossible to chew.   Stacy says genetic testing saved her life but admits it is not for everybody because the decision to go forth with such testing is a deeply personal decision because some people don't want to know what the tests could reveal. Despite her cancer journey, Stacy lives a happy life.  She resumed her passion of hiking near her home in Chattanooga, Tennessee, and consumption of nuts resulted in her establishing Seahorse Snacks, which she operates out of her home.   Additional Resources:   Seahorse Snacks: https://www.seahorsesnacks.com   No Stomach For Cancer: https://www.nostomachforcancer.org          

OffScrip with Matthew Zachary
Standard Deviation EP3: The Weight

OffScrip with Matthew Zachary

Play Episode Listen Later Nov 6, 2025 14:56


When the system kills a $2.4 million study on Black maternal health with one Friday afternoon email, the message is loud and clear: stop asking questions that make power uncomfortable. Dr. Jaime Slaughter-Acey, an epidemiologist at UNC, built a groundbreaking project called LIFE-2 to uncover how racism and stress shape the biology of pregnancy. It was science rooted in community, humanity, and truth. Then NIH pulled the plug, calling her work “DEI.” Jaime didn't quit. She fought back, turning her grief into art and her outrage into action. This episode is about the cost of integrity, the politics of science, and what happens when researchers refuse to stay silent.RELATED LINKS• The Guardian article• NIH Grant• Jaime's LinkedIn Post• Jaime's Website• Faculty PageFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Healthy As A Mother
#137: Things We Wish We Knew Before IVF About Infertility - With My Husband, Mike Gordon

Healthy As A Mother

Play Episode Listen Later Nov 5, 2025 51:51


Join Womanhood Wellness to learn more about all of the things we discuss in this episode.What if the world really was rigged in your favor, even when your fertility journey feels impossible?In this episode, Dr.Leah sits down with her husband, Mike, to unpack their six-year journey through severe male factor infertility that eventually led them to IVF. Mike shares the raw truths and lessons he wishes every man knew before stepping into this process, from the mindset that kept him grounded to the habits and testing that changed everything.They get real about the hardest moments, the difference between fighting and surrendering, and the mindset shift that made the impossible feel bearable. It's not a how-to guide, it's a story about meaning, surrender, and what it really takes to stay connected through the storm.Because… sometimes the only way forward is trusting that even this is happening for you.You'll Learn:[00:00] Introduction[04:52] Why viewing life as “rigged in your favor” can shift infertility grief into gratitude[08:03] The critical balance between fighting for answers and surrendering control[09:39] Why avoiding testing keeps men stuck in ego instead of empowered[12:38] How releasing judgment and embracing IVF with excitement changes the experience[14:28] Everyday toxins that quietly damage testosterone and sperm quality[20:28] The truth about EMFs and keeping phones in your pockets[22:32] Which supplements and detox tools actually matter for men's sperm health[37:22] The difference between ejaculated and immature sperm can determine IVF success[43:47] The important lesson their six-year journey revealed about finding meaning in struggleResources Mentioned:Peter Sage Academy | WebsiteNeeded – Men's Fertility Line | WebsiteGood Clean Love Lubricants | WebsiteCoconu – Water-Based or Oil-Based Lubricant | WebsiteYes – Organic Lubricant | WebsiteFind more from Dr. Leah:Dr. Leah Gordon | InstagramDr. Leah Gordon | WebsiteWomanhood Wellness | WebsiteFind more from Dr. Morgan:Dr. Morgan MacDermott | InstagramDr. Morgan MacDermott | WebsiteUse code HEALTHYMOTHER and save 15% at RedmondFor 20% off your first order at Needed, use code HEALTHYMOTHERSave $260 at Lumebox, use code HEALTHYASAMOTHER

Remember Me
Should I get genetic testing?

Remember Me

Play Episode Listen Later Nov 5, 2025 57:20


We're tackling the question - Should I get genetic testing?We have the incredible return guest - Erynn Gordon, CGC, program manager at Progranulin Information Navigator. We also brought on some incredible advocates in the FTD Community - Annika from Cure MAPT FTD, Jackie & Wanda from CureGRN and Michael from End the Legacy to share their personal experiences and thought processes around genetic testing.Let us know what you think when you listen. - R+MA VERY special thank you to today's sponsors Progranulin Information Navigator and Psilera. FTD Genetic Resources:Progranulin Information NavigatorCure MAPT FTDCureGRNEnd The Legacy - ALS & FTDFTD Disorders RegistryThe Penn FTD Center Genetics ResourcesThe AFTD Genetics OverviewThe National Society of Genetic CounselorsUCSF Memory Familial FTD PageWant to support the podcast + get more content? Join us on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Patreon⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠! You get exclusive content + a space to share and connect with others. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.patreon.com/remembermecommunity⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ If you're curious about anything RM, we'd love to connect with you on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram, and visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠our website at⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ www.remembermeftd.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, all the latest updates! ------Remember Me Podcast + Community is here to offer hope + human connection for families, caregivers, and individuals impacted by Frontotemporal Dementia (FTD). Always, always accept the good.

rm genetic testing cgc frontotemporal dementia ftd
OffScrip with Matthew Zachary
Stand By She: Allison Applebaum

OffScrip with Matthew Zachary

Play Episode Listen Later Nov 4, 2025 39:37


EPISODE DESCRIPTIONAllison Applebaum was supposed to become a concert pianist. She chose ballet instead. Then 9/11 hit, and she ran straight into a psych ward—on purpose. What followed was one of the most quietly revolutionary acts in modern medicine: founding the country's first mental health clinic for caregivers. Because the system had decided that if you love someone dying, you don't get care. You get to wait in the hallway.She's a clinical psychologist. A former dancer. A daughter who sat next to her dad—legendary arranger of Stand By Me—through every ER visit, hallway wait, and impossible choice. Now she's training hospitals across the country to finally treat caregivers like patients. With names. With needs. With billing codes.We talked about music, grief, psycho-oncology, the real cost of invisible labor, and why no one gives a shit about the person driving you to chemo. This one's for the ones in the waiting room.RELATED LINKSAllisonApplebaum.comStand By Me – The BookLinkedInInstagramThe Elbaum Family Center for Caregiving at Mount SinaiFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Real Pink
Episode 357: When the Caregiver Needs Care

Real Pink

Play Episode Listen Later Nov 3, 2025 16:30


Today on Real Pink, we are joined by someone w ho knows what it means to care deeply for others and what it feels like when life suddenly requires that same care and compassion be turned inward. She's a devoted mother and caregiver to her son, and when she was diagnosed with breast cancer, she found that she was more mentally prepared to navigate it than expected. Sabrina Thomas is here to tell her story, including how she advocated for herself and learned to accept help from others when she's so used to being the one who gives it. This conversation is a reminder that strength comes in many forms.

SAGE Clinical Medicine & Research
CPC 2025 Podcast: Genetic Testing in Craniofacial Care: Development of Algorithms for Testing Patients with Orofacial Clefting, Branchial Arch Anomalies, and Craniosynostosis

SAGE Clinical Medicine & Research

Play Episode Listen Later Oct 31, 2025 24:09


In this episode of the Cleft Palate Craniofacial Journal podcast series, Pat Chibbaro, Multimedia Specialist, interviews Maria Mills, author of the CPCJ article entitled, "Genetic Testing in Craniofacial Care: Development of Algorithms for Testing Patients with Orofacial Clefting, Branchial Arch Anomalies, and Craniosynostosis" (coauthored by Emily R. Gallagher, Penny Chow, Hazel Perry, Allison C. Tam, Glenn Rosenbluth, Yvonne R. Gutierrez, Jessica Kianmahd Shamshoni, Marisa Matthews, Daniela N. Schweitzer, and Anne Hing).

The Human Upgrade with Dave Asprey
Biohacking Cannabis: The DNA Science of Plant Medicine : 1353

The Human Upgrade with Dave Asprey

Play Episode Listen Later Oct 28, 2025 43:13


Discover how decoding your DNA can unlock the full potential of plant medicine. This episode delivers a cannabis masterclass for biohackers, revealing how personalized genetics are transforming human performance, brain optimization, and longevity. You'll learn how to identify your ideal cannabis and supplement protocols, balance your endocannabinoid system, and turn precision data into powerful healing. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Len May, MSc, visionary authority in personalized medicine and CEO of EndoDNA, the world leader in DNA-based wellness technology. With over 25 years of pioneering work in genomics, epigenetics, and medicinal cannabis, Len's patented DNA decoding system maps your unique genotypes to design tailor-made health solutions. His company holds the world's largest real-world efficacy database in precision wellness, integrating functional medicine, AI-driven analytics, and genetic data to create personalized blueprints for optimal brain function and performance. Together, Dave and Len explore how your genetic code determines how you respond to cannabis, psychedelics, nootropics, and supplements—and how to use that data to reduce anxiety, improve sleep optimization, and enhance focus. You'll learn how decoding your DNA can guide anti-aging strategies, mitochondrial performance, metabolism, and neuroplasticity, revealing new ways to live longer and smarter. This episode dives deep into the intersection of cannabis science, genomics, and biohacking. You'll discover how genetic polymorphisms influence mood, cognition, and stress response, and how personalized medicine can help you make smarter decisions around ketosis, fasting, and recovery. From optimizing the endocannabinoid system to hacking your biology for resilience and longevity, this is the future of functional medicine in action. You'll Learn: • How the endocannabinoid system regulates mood, focus, pain, and stress response • Which genetic polymorphisms affect cannabis sensitivity, anxiety risk, and dosing windows • How to use DNA testing to select cannabinoid and terpene ratios that fit your biology • Why delivery method matters and when sublingual dosing outperforms inhalation • How personalized cannabis protocols can support sleep optimization, recovery, and emotional regulation • The role of cannabinoids in mitochondrial function, neuroplasticity, and cognitive performance • How pharmacogenomics reduces antidepressant side effects and improves treatment matching • How to screen genetics for safer psychedelic use and avoid adverse reactions • What HLA and related markers reveal about mold sensitivity and inflammation This is essential listening for anyone serious about biohacking, brain optimization, longevity, anti-aging, functional medicine, and living Smarter Not Harder—with precision tools designed to upgrade your mind and body at the genetic level. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cannabis biohacking, cannabis masterclass, Dave Asprey cannabis, DNA decoding, genetic testing for cannabis, personalized medicine, endocannabinoid system, cannabis genomics, cannabis and DNA, cannabis and genetics, cannabis nootropics, plant medicine biohacking, cannabis brain optimization, cannabis and neuroplasticity, cannabis for focus, cannabis and mitochondria, cannabis metabolism, cannabis for sleep, cannabis anti-aging, precision wellness, functional medicine, cannabis longevity, EndoDNA, Len May, cannabis and AI, biohacking genetics, cannabis and fasting, cannabis and ketosis, personalized supplements, cannabis and mood, cannabis stress response, genetic biohacking, cannabis cognitive performance Thank you to our sponsors! -Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave. -Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -iRestore | Use code DAVE at https://www.irestore.com/ to unlock an exclusive discount on the iRestore Elite. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 – Trailer • 1:25 – Introduction • 7:02 – Cannabis & The Endocannabinoid System • 13:30 – How It Works • 21:38 – Brain Health & Clinical Studies • 26:52 – Psychedelics & Genetic Testing • 31:37 – Genetics vs Epigenetics • 34:53 – Antidepressant Safety • 40:41 – Cannabis Success Stories • 46:02 – ADHD & Personality Genes • 50:54 – Mold, Nicotine & Mitochondria • 55:27 – GLP-1 & Metabolism • 1:00:34 – Microbiome & Medical Freedom See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Jockers Functional Nutrition
What I Never Learned About Vaccines in Medical School with Dr. Joel Warsh

Dr. Jockers Functional Nutrition

Play Episode Listen Later Oct 28, 2025 66:10


In this episode, Dr. Jockers talks with Dr. Joel Warsh about what doctors aren't taught about vaccines in medical school and why long-term safety research is still missing. They explore how the rise in chronic illness among kids might connect to current vaccine practices. Dr. Warsh explains why asking hard questions isn't being "anti-science" — it's how we make medicine safer. He shares why vaccine schedules should be personalized and how real informed consent helps parents make better choices. Together, they break down what's actually in vaccines, how they're tested, and why open, honest conversations about health are long overdue. In This Episode: 00:00 Introduction: Vaccine Safety Concerns 02:38 Interview Introduction: Dr. Joel Warsh 02:51 The Chronic Disease Epidemic in Children 04:06 Personal Stance on Vaccination 06:33 The Rise of Chronic Diseases in Children 08:28 Factors Contributing to Chronic Diseases 09:50 Political and Environmental Influences on Health 17:30 The Role of Medications in Modern Health 19:29 Medical Training and Nutrition 23:59 Historical Context of Vaccines 30:32 How Vaccines Work and Personalized Medicine 33:59 Exploring Vaccine Reactions and Genetic Testing 36:38 The Controversy Surrounding Hepatitis B Vaccine 41:21 Questioning Vaccine Safety and Placebo Studies 45:42 Concerns About Vaccine Ingredients 59:33 The Need for Better Vaccines and Open Discussion 01:03:58 Conclusion and Final Thoughts If you want a nutrient-packed boost, check out Paleo Valley's Grass-Fed Organ Complex—a supercharged multivitamin containing liver, heart, and kidney from healthy pasture-raised cows. It delivers a full spectrum of B vitamins, minerals, amino acids, and peptides without the strong taste of organ meat. For a 15% discount, visit paleovalley.com/jockers and stock up on this powerful supplement to support energy, mental clarity, and overall health. Looking to boost your digestion, immunity, and energy? Just Thrive Probiotic is the answer! Unlike most probiotics that get destroyed by stomach acid, Just Thrive is clinically proven to reach your gut 100% alive. This means better digestion, improved immunity, enhanced energy, and easier weight management. Plus, with their industry-leading 100% money-back guarantee, you've got nothing to lose. Save 20% off your order with code JOCKERS at justthrivehealth.com. "It's not about whether vaccines are good or bad, but about creating a system that better assesses their long-term safety and impacts." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Get 15% off Paleovalley: paleovalley.com/jockers – Use code JOCKERS Save 20% on Just Thrive: justthrivehealth.com – Use code JOCKERS Connect with Dr. Joel Warsh: Website: https://integrativepediatrics.com/ Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/

OffScrip with Matthew Zachary
Sick Days Not Included: Rebecca V. Nellis

OffScrip with Matthew Zachary

Play Episode Listen Later Oct 28, 2025 59:04


EPISODE DESCRIPTIONRebecca V. Nellis never meant to run a nonprofit. She just never left. Twenty years later, she's still helming Cancer and Careers after a Craigslist maternity-leave temp job turned into a lifelong mission.In this 60-minute doubleheader, we cover everything from theater nerdom and improv rules for surviving bureaucracy, to hanging up on Jon Bon Jovi, to navigating cancer while working—or working while surviving cancer. Same thing.Rebecca's path is part Second City, part Prague hostel, part Upper East Side grant writer, and somehow all of that makes perfect sense. She breaks down how theater kids become nonprofit lifers, how “sample sale feminism” helped shape a cancer rights org, and how you know when the work is finally worth staying for.Also: Cleavon Little. Tap Dance Kid. 42 countries. And one extremely awkward moment involving a room full of women's handbags and one very confused Matthew.If you've ever had to hide your diagnosis to keep a job—or wanted to burn the whole HR system down—this one's for you.RELATED LINKSCancer and CareersRebecca Nellis on LinkedIn2024 Cancer and Careers Research ReportWorking with Cancer Pledge (Publicis)CEW FoundationI'm Not Rappaport – Broadway InfoFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship opportunities, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

SaaS Fuel
Genetics and Healing: A New Path in Pain Management | James Piacentino | 331

SaaS Fuel

Play Episode Listen Later Oct 28, 2025 57:21


In this special SaaS Fuel episode, host Jeff Mains welcomes James Piacentino, co-founder and CEO of Thrive Genetics—a company at the intersection of healthcare, genetics, technology, and compassionate mission. James shares his deeply personal connection to the opioid crisis, describing the family loss that shaped his life's purpose and eventually sparked the founding of Thrive Genetics.The conversation explores how advances in genetic testing, behavioral analysis, and AI are enabling physicians to proactively identify and mitigate addiction risk—before opioids are prescribed. Along the way, they discuss building solutions in complex, regulated markets, the importance of pilots and product-market fit, and why mission-driven leadership can turn innovation into real-world impact.Key Takeaways00:00 "Building Leaders and Scaling Success"06:25 Generational Trauma: Beyond Genetics07:24 Breaking Cycles Through Innovation11:53 High Pain Procedures and Opioids15:30 "Genetic Testing for Addiction Risk"20:09 Market Applications and Opportunities22:48 Integrated Healthcare Ecosystem Insights25:43 "Customer-Centered Product Development Insights"29:36 "Vision and Path to Scale"33:52 Streamlining Customer Service Efficiency37:27 "Focus on Solutions, Not Problems"40:01 Simplifying Healthcare Innovation43:18 "Collaborate for Impactful Leadership"47:18 AI Monitors Patient Pain Signals49:50 "Simple Design, De-Identified Data"52:16 "Embracing Rejection as Growth"55:36 "Fractional Legal & Personality Insights"Tweetable QuotesViral Topic: Building Products That Truly Fit Customer Needs: "It's very important to sit with your customer and just literally build the product to ensure that you are satisfying those specific business needs." — James PiacentinoViral Topic: Simplicity in Healthcare Innovation: "Complicated's fun and tech, maybe, but when you get into these healthcare scenarios, it's gotta be really, really lean, simple." — James Piacentino Viral Topic: Keep It Simple in Complex Systems: "We're just giving you some Information to use. We're not telling you you should. You should drive here or not, you know, so it was like a very simple workaround to something that could have been awfully complex, especially for what we're doing." — James PiacentinoViral Topic: Rethinking Opioid Addiction Prevention: "Why is it that we only talk about addiction after it happens, when technology now makes it possible to see the risk before the first prescription is even written?" — Jeff MainsViral Topic: The Future of Opioid Prescription"Advancements in personalized medicine are helping physicians make better informed decisions, balancing the need for pain relief with the responsibility to prevent addiction." — Jeff Mains Healthcare Innovation Mindset: "You don't have to tackle the bear, just drive by and wave." — Jeff Mains SaaS Leadership LessonsMission Drives Resilience:Stay true to your personal and company values, especially in high-stakes industries. Purpose fuels perseverance through complexity.Customer Collaboration is Key:Meet customers where they are. Continuously incorporate their feedback to ensure product-market fit and genuine value.Embrace Simplicity:In regulated spaces, complexity can kill progress. Strive for solutions that minimize barriers for adoption and use.Learn from the ‘No's:Rejection (from investors or stakeholders) is a gift. Each “no” teaches you something new to incorporate or consider.Surround...

Real Pink
Episode 356: Finding Strength, Sharing Hope: Guerdy Abraira on Life After Breast Cancer

Real Pink

Play Episode Listen Later Oct 27, 2025 24:49


Welcome to the Komen Health Equity Revolution podcast series on Real Pink. Each month, we bring together patients, community partners, health care providers, researchers and advocates to talk about real challenges and real solutions driving the health equity revolution. Together, we're working to close the gaps and create a future of breast health equity for all. We are honored to be joined by Guerdy Abraira. You may know her from The Real Housewives of Miami, but beyond the cameras, Guerdy has shown incredible strength and resilience as a breast cancer survivor. This National Breast Cancer Awareness Month, we're talking about the power of sharing your story, building community and why organizations like Susan G. Komen are committed to ensuring that no one faces breast cancer alone.

Living With Cystic Fibrosis
Live Podcast: Harvest of Hope

Living With Cystic Fibrosis

Play Episode Listen Later Oct 27, 2025 19:25


Our Harvest of Hope Gala was unforgettable—so much love, energy, and sparkle! The theme this year was Diamonds and Denim, and the outfits did not disappoint.Huge thanks to our co-chair, Heather Trammell. Heather is not only a CF mom but also a source of wisdom and support in our community. She did an amazing job organizing the Gala and has already committed to leading again in 2026. Heather and her husband Chris (who, fun fact, is now best friends with Joe Bonnell) bring so much heart to our mission.We were also grateful to have Tara Fahrner with us. Tara is a CF mom to 2½-year-old Beau, who was diagnosed at birth through newborn screening. Tara describes the diagnosis as a shock, but she's thankful for the strong CF community that has surrounded her family. She and Heather both serve on the Quality Improvement Team at the University of Michigan as well as our Advisory Board.And a big shout-out to Dave Ingraham, who traveled three hours from Lake City, Michigan, to be at the Gala. Dave's truck is wrapped with The Bonnell Foundation logo and QR code, and he drives it in parades to spread awareness. He's fully embraced his granddaughter Briar Lynn's journey with CF, supporting both her and his daughter, a single mom. His dedication is inspiring. Please like, subscribe, and comment on our podcasts!Please consider making a donation: https://thebonnellfoundation.org/donate/The Bonnell Foundation website:https://thebonnellfoundation.orgEmail us at: thebonnellfoundation@gmail.com Watch our podcasts on YouTube: https://www.youtube.com/@laurabonnell1136/featuredThanks to our sponsors:Vertex: https://www.vrtx.comViatris: https://www.viatris.com/en

Health for Life
High-Risk Screening, Genetic Testing, and Expertise in Breast Imaging with Dr. Adrian Miller of Peeples Cancer Institute at Hamilton Medical Center

Health for Life

Play Episode Listen Later Oct 26, 2025 14:52


Dr. Adrian Miller is a board-certified, fellowship trained radiologist in breast imaging at Peeples Cancer Institute at Hamilton Medical Center in Dalton, Georgia.For more information about Peeples Cancer Institute, call 844-PCI-HOPE or visit VitruvianHealth.com/cancer.This program in no way seeks to diagnose or treat illness or to replace professional medical care. Please see your healthcare provider if you have a health problem.

SHE MD
Olivia Munn & Leading Voices on Early Detection, AI, and Breast Cancer Prevention

SHE MD

Play Episode Listen Later Oct 23, 2025 54:32


In this special live episode of the SHE MD Podcast, Olivia Munn joins Dr. Thaïs Aliabadi, Mary Alice Haney, Dr. Shari Goldfarb, and Kristen Dahlgren, for a powerful Breast Cancer Awareness Month panel in New York City. The event coincided with NBC's Today Show coverage and the lighting of the Empire State Building in pink — marking the launch of a national conversation around early detection, AI, and prevention.Together, they explore how lifetime risk assessments, dense breast screening, and AI mammogram prediction tools like Clarity Breast are transforming breast health. The panel also discusses cancer vaccine research, genetic testing, and the importance of women knowing their individual risk scores.Listeners will hear Olivia's personal story of early detection after a high-risk score prompted further imaging, leading to her diagnosis and recovery. This episode offers clarity, action, and hope — empowering every listener to become their own health advocate and partner with their medical team.Subscribe to SHE MD Podcast for expert tips on PCOS, Endometriosis, fertility, and hormonal balance. Share with friends and visit the SHE MD website and Ovii for research-backed resources, holistic health strategies, and expert guidance on women's health and well-being.What You'll LearnHow lifetime risk assessment tools can identify breast cancer risk before symptoms appearWhy dense breast tissue requires supplemental screening beyond mammogramsHow AI predictive tools like Clarity Breast are revolutionizing early detectionThe promise of vaccine research and genetic testing in future breast cancer preventionKey Timestamps(00:00) Live event intro and Breast Cancer Awareness Month context(03:30) Olivia's story: risk score, MRI findings, and early diagnosis(13:00) Dr. Aliabadi and Dr. Goldfarb on dense breast screening and AI tools(16:00) Cancer vaccine and immunotherapy discussion with Kristen Dahlgren(27:00) Genetic testing and family history: understanding your risk(34:00) Audience Q&A: emotional recovery and advocacy(42:00) Is there support for young women being diagnosed with breast cancer?(51:30) Clarifying the term Risk AssessmentKey TakeawaysEvery woman should know her lifetime breast cancer risk scoreDense breasts may obscure cancers — MRI and ultrasound can save livesAI mammogram tools are changing detection from reactive to predictiveResearch into cancer vaccines offers hope for prevention and recurrence reductionAdvocacy and awareness remain key — early action leads to better outcomesGuest BiosOlivia MunnOlivia Munn is an actress, health advocate, and breast cancer survivor. After receiving a high lifetime risk assessment score, she underwent further imaging that revealed cancer across multiple quadrants, leading to a bilateral mastectomy. Since publicly sharing her diagnosis in 2024, she has dedicated her platform toward raising awareness about early detection, risk assessment, and empowering women with knowledge about their breast health.Dr. Shari Goldfarb, MDDr. Shari Goldfarb is a breast medical oncologist at Memorial Sloan Kettering, with a clinical focus on early and advanced breast cancer. Her research centers on survivorship, symptom management, fertility, sexual health, and quality of life for breast cancer patients. She participates in clinical trials aimed at improving outcomes for women during and after treatment.Kristen DahlgrenKristen Dahlgren is a former NBC correspondent who, after her own stage 2 breast cancer diagnosis, left journalism to found the Cancer Vaccine Coalition. She collaborates with top cancer centers to accelerate immunotherapy and vaccine development in breast cancer and advocates for preventive strategies beyond current standards.LinksOlivia Munn – https://www.instagram.com/oliviamunnDr. Shari Goldfarb – https://www.mskcc.org/profile/shari-goldfarbKristen Dahlgren – https://www.linkedin.com/in/kristen-dahlgren-886519292/Donna McKay – https://www.bcrf.org/teamResources MentionedBreast Cancer Research Foundation (BCRF) – Funding for innovative breast cancer research and prevention programs

We Can Do Hard Things with Glennon Doyle
Life-Saving Intel: Amanda's Breast Cancer Surgeon Dr. Lucy De La Cruz

We Can Do Hard Things with Glennon Doyle

Play Episode Listen Later Oct 21, 2025 107:25


This life-saving conversation is for anyone who has—or loves someone who has—breasts. It's what to look for, what to ask, what screenings you *actually need* (not just what is offered), and every decision point you have (even if it's not offered to you) if you are facing surgery.   This Breast Cancer Awareness Month, Glennon, Abby, and Amanda empower us with the most vital tool we have: information. Amanda reflects on how self-advocacy led her to her own breast cancer diagnosis—and we hear from the pod squad about how Amanda's transparency helped save their lives. Then, we're joined by Amanda's renowned doctor, Dr. Lucy M. De La Cruz, who reminds us that every patient has agency—and shares how to choose the treatment path that's right for you. And special shout out and thanks to Pod Squader Lori Mihalich-Levin (@mindfulreturn) for being such a special part of this story! If you or someone you love has been diagnosed with breast cancer, please save this episode or send it to the people you love. We love you.  For more on Amanda's Breast Cancer journey:  - Amanda's Diagnosis and What's Next (Part 1) - Amanda's Diagnosis and What's Next (Part 2) - Amanda Returns Post Surgery: Here's What She Wants You to Know  - What Amanda's Learned About Life, Love & Community (Post Surgery Pt 2)  - Early Detection, Mammograms & Breast Cancer Care with Dr. Rachel Brem  - Expert Advice on Genetic Testing, Cancer Prevention & Care Disparities with Dr. Rachel Brem  About Dr. De La Cruz:  Dr. Lucy M. De La Cruz is an internationally recognized breast surgical oncologist and the youngest Latina Chief of Breast Surgery in an academic institution in the United States. She serves as Chief of Breast Surgery and Director of the Betty Lou Ourisman Breast Health Center at MedStar Georgetown University Hospital, a nationally ranked center of excellence in breast cancer care. Dr. De La Cruz specializes in nipple-sparing mastectomies with structural preservation and resensation, with a focus on highly specialized single-stage implant reconstruction. Patients describe her not only as a world-class surgeon, but as a fierce advocate and mentor—especially for women navigating the complexities of diagnosis, treatment, and survivorship. 

OffScrip with Matthew Zachary
GenX Therapy With Sally Wolf

OffScrip with Matthew Zachary

Play Episode Listen Later Oct 21, 2025 41:12


Sally Wolf is back in the studio and this time we left cancer at the door. She turned 50, brought a 1993 Newsday valedictorian article as a prop, and sat down with me for a half hour of pure Gen X therapy. We dug into VHS tracking, Red Dawn paranoia, Michael J. Fox, Bette Midler, and how growing up with no helmets and playgrounds built over concrete somehow didn't kill us.We laughed about being Jewish kids in the suburbs, the crushes we had on thirty-year-olds playing teenagers, and what it means to hit 50 with your humor intact. This episode is part nostalgia trip, part roast of our own generation, and part meditation on the privilege of being alive long enough to look back at it all. If you ever watched Different Strokes “very special episodes” or had a Family Ties lunchbox, this one's for you.RELATED LINKSSally Wolf Official WebsiteSally Wolf on LinkedInSally Wolf on InstagramCosmopolitan Essay: “What It's Like to Have the ‘Good' Cancer”Oprah Daily: “Five Things I Wish Everyone Understood About My Metastatic Breast Cancer Diagnosis”Allure Breast Cancer Photo ShootTom Wilson's “Stop Asking Me the Question” SongFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Real Pink
Episode 355: Real Talk: Our Family Only Knows Life with Cancer

Real Pink

Play Episode Listen Later Oct 20, 2025 28:30


Today we are speaking with a family who only knows life with breast cancer. With a strong family history of both breast cancer and BRCA gene mutations on the maternal side, everyone has always wondered “when”, not “if” breast cancer would affect them too. When Kathryn was diagnosed in her early 30's like her mother was, it unveiled the difficulties of being diagnosed as a young woman. It also spurred a series of decisions by her two sisters, one of which is her twin. This is a story of support, empowerment, struggle, guilt and pain, but most of all, family. Today we welcome sisters Kathryn, Christine and Cara and their mom Vicki to the show to talk about experiences.

Once Upon A Gene
Why Genetic Testing Matters: The Case for Genetic Testing and the Start Genetic Movement - with Geraldine Bliss

Once Upon A Gene

Play Episode Listen Later Oct 16, 2025 46:37


In this episode of Once Upon a Gene, host Effie Parks welcomes Geraldine Bliss — rare mom, co-founder of CureSHANK, and the powerhouse behind Start Genetic, a new movement empowering families to take control of their genetic testing journey. Geraldine shares her decades-long experience as mom to Charles, a 27-year-old living with Phelan-McDermid syndrome, and how one test unlocked a world of understanding, care, and connection. Together, Effie and Geraldine dig into the real-world impact of genetic testing — what to ask for, when to push for answers, and how knowing the cause changes everything. They cover:

OffScrip with Matthew Zachary
Standard Deviation EP2: Domino Effect

OffScrip with Matthew Zachary

Play Episode Listen Later Oct 16, 2025 10:43


Dr. Nikki Maphis didn't just lose a grant. She lost a lifeline. An early-career Alzheimer's researcher driven by her grandmother's diagnosis, Nikki poured years into her work—only to watch it vanish when the NIH's MOSAIC program got axed overnight. Her application wasn't rejected. It was deleted. No feedback. No score. Just gone.In this episode, Oliver Bogler pulls back the curtain on what happens when politics and science collide and promising scientists get crushed in the crossfire. Nikki shares how she's fighting to stay in the field, teaching the next generation, and rewriting her grant for a world where even the word “diversity” can get you blacklisted. The conversation is raw, human, and maddening—a reminder that the real “war on science” doesn't happen in labs. It happens in inboxes.RELATED LINKS:• Dr. Nikki Maphis LinkedIn page• Dr. Nikki Maphis' page at the University of New Mexico• Vanguard News Group coverage• Nature article• PNAS: Contribution of NIH funding to new drug approvals 2010–2016FEEDBACK:Like this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, visit outofpatients.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Dance Of Life Podcast with Tudor Alexander
Healthy Like a Fox: Testing & Detox

The Dance Of Life Podcast with Tudor Alexander

Play Episode Listen Later Oct 16, 2025 74:13


God gave us a body to take care of and it is important to maintain that body with love and care. Especially because we are at the end of the genesis curse, there are many considerations these days to living a healthy life. It is also important from an eschatological perspective, because one day the world will ostracize those who do not obey its counterfeit system of worship — which means we must not be dependent on institutions or pharmaceutical drugs as much as possible. In this free series I go over 20 years of experience in the realm of health and wellness and discuss important strategies on how to maintain what we've been given so that you can be as healthy as possible for what's to come. * 00:00 - Introduction* 06:56 - Genetic Testing* 14:36 - Testing for Nutrients* 30:20 - Detox This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.danceoflife.com/subscribe

SurgOnc Today
SSO Education Series: Point of Care Genetic Testing and Pitfalls to Avoid

SurgOnc Today

Play Episode Listen Later Oct 16, 2025 16:27


In this episode of SurgOnc Today, Dr. Doreen Agnese, Dr. Anna C Beck and Dr. Andrea Abbott will discuss different delivery models for genetic testing, including traditional genetic testing and point of care testing.  We will discuss potential pitfalls associated with point of care testing and interpretation of results.

Success Leaves Clues with Robin Bailey and Al McDonald
Success Leaves Clues: Ep268 - Transforming Preventive Healthcare Through Lifestyle Medicine with guest Carl Aube, Co-Founder, Optimal U Inc.

Success Leaves Clues with Robin Bailey and Al McDonald

Play Episode Listen Later Oct 16, 2025 38:53


In this episode of Success Leaves Clues, hosts Robin and Al sit down with Carl Aube, Co-Founder at Optimal U Inc., to explore how lifestyle medicine is transforming preventive health across Canada. With over 25 years of experience in healthcare innovation, Carl shares how Optimal U is bridging the gap between public and private care – empowering individuals to take charge of their health through data-driven assessments, personalized care plans, and actionable lifestyle changes. Carl discusses how small, daily habits create measurable, long-term health outcomes, and how wearables, genetic testing, and AI are helping Canadians stay healthier longer. He also explains how employers can integrate lifestyle medicine into benefits programs to boost productivity, reduce absenteeism, and lower healthcare costs. This episode is a wake-up call for anyone who believes “ignorance is bliss” when it comes to their health, and an invitation to start planting the seeds of wellness today. You'll hear about: From Sick Care to Preventive Care: Why Canada's public system focuses on treatment, and how Optimal U fills the prevention gap. The Six Pillars of Lifestyle Medicine: Nutrition, exercise, sleep, stress, social connection, and avoiding risky substances. Data-Driven Health: How bloodwork, genetic screening, and wearables reveal what your body truly needs. Ignorance Isn't Bliss: Why knowing your health risks early empowers better choices and longer vitality. Employers and Well-Being: How companies can use lifestyle medicine to reduce costs and build healthier, more engaged teams. The Future of Personalized Care: How AI and continuous monitoring are making wellness more accessible and actionable than ever. If you're a benefits advisor, HR leader, or parent looking to better support families through smarter healthcare access, this episode will open your eyes to how innovation and empathy can work hand-in-hand to change the future of care in Canada. We talk about: 00:00 Introduction 03:00 What Is Optimal U and How It Works with the Public System 05:00 Prevention vs. Treatment: Why Lifestyle Medicine Matters 07:00 The Six Pillars of Lifestyle Health 09:00 Facing Your Health Fears and Taking Action 12:00 From Data to Daily Habits: Sleep, Movement, and Nutrition 14:00 How AI and Wearables Empower Real-Time Health Insights 16:00 The Mission Behind Optimal U and Carl's 25-Year Journey 18:00 Breaking Down Healthcare Silos and Improving Referrals 21:00 Integrating Lifestyle Medicine into Employee Benefits 23:00 Real ROI for Employers: Productivity, Wellness, and Retention 26:00 Lifestyle vs. Functional Medicine: What's the Difference? 29:00 Genetic Testing and the Power of Personalized Insights 36:00 Working with Family Physicians and Navigating the Public System 40:00 Collaboration Over Competition in Healthcare 41:00 Planting Seeds of Health: Carl's Vision for the Future Connect with Carl LinkedIn: https://www.linkedin.com/in/carl-aube/ Website: https://optimalu.ca/ Connect with Us LinkedIn: Robin Bailey and Al McDonald Website: Aria Benefits and Life & Legacy Advisory Group

OffScrip with Matthew Zachary
Family Reach: The Charity America Forced Into Existence

OffScrip with Matthew Zachary

Play Episode Listen Later Oct 14, 2025 40:59


Carla Tardiff has spent 17 years as the CEO of Family Reach, a nonprofit that shouldn't have to exist but absolutely does—because in America, cancer comes with a price tag your insurance doesn't cover.We talk about shame, fear, burnout, Wegmans, Syracuse, celebrity telethons, and the godforsaken reality of choosing between food and treatment. Carla's a lifer in this fight, holding the line between humanity and bureaucracy, between data and decency. She's also sharp as hell, deeply funny, and more purpose-driven than half of Congress on a good day.This episode is about the work no one wants to do, the stuff no one wants to say, and why staying angry might be the only way to stay sane.Come for the laughs. Stay for the rage. And find out why Family Reach is the only adult in the room.RELATED LINKSFamily ReachFinancial Resource CenterCarla on LinkedInMorgridge Foundation ProfileAuthority Magazine InterviewSyracuse University FeatureFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Healthcare's Missing Link
NAD, Genes, and Longevity

Healthcare's Missing Link

Play Episode Listen Later Oct 14, 2025 28:32


In this episode, we unpack the vital role of NAD in cellular energy, metabolism, immune function, and sleep. Learn how precursors like NMN and NR support NAD production and why delivery method matters. We explore how genetics influence your response to food, exercise, and toxins—and how personalized testing can unlock better recovery, performance, and longevity. From DNA to mitochondria, this conversation blends science with actionable insights for living younger, longer.Get a FREE copy of Health, Hope & Freedom: https://sherwood.tv/For Kingdom Products visit: https://shop.fmidr.com/Interested in becoming a patient? https://fmidr.com/plans/Our privacy policy & disclaimer apply to this video. You can view the details here:https://fmidr.com/privacy-policy#NADBoost, #LongevityScience, #MitochondrialHealth, #DNARepair, #HealthyAging, #GeneticTesting, #CellularEnergy, #SleepRecovery, #MetabolicHealth, #BiohackingLife, #SirtuinActivation, #PerformanceGenetics

Real Pink
Episode 354: Beyond the Pink Ribbon: Living with Metastatic Breast Cancer

Real Pink

Play Episode Listen Later Oct 13, 2025 21:16


During National Breast Cancer Awareness Month, breast cancer gets more attention and that is a great thing for fundraising, awareness and early detection. However, for those living with Metastatic Breast Cancer, this month can be hard – and sometimes feel triggering and isolating. The widespread focus is often on screenings and celebrating survivors living a life free from cancer, which is not the reality for those with metastatic disease. Today, on MBC Awareness Day, we are excited to welcome Ashley Fernendez back to the show to talk about her lived experiences, how she seeks support and what she wants people to know about living with Metastatic Breast Cancer.

OffScrip with Matthew Zachary
The Genes of Wrath: Jennifer J. Brown

OffScrip with Matthew Zachary

Play Episode Listen Later Oct 7, 2025 40:46


Jennifer J. Brown is a scientist, a writer, and a mother who never got the luxury of separating those roles. Her memoir When the Baby Is Not OK: Hopes & Genes is a punch to the gut of polite society and a medical system that expects parents to smile through trauma. She wrote it because she had to. Because the people who gave her the diagnosis didn't give her the truth. Because a Harvard-educated geneticist with two daughters born with PKU still couldn't get a straight answer from the very system she trained in.We sat down in the studio to talk about the unbearable loneliness of rare disease parenting, the disconnect between medical knowledge and human connection, and what it means to weaponize science against silence. She talks about bias in the NICU, the failure of healthcare communication, and why “resilience” is a lazy word. Her daughters are grown now. One's a playwright. One's an artist. And Jennifer is still raising hell.This is a conversation about control, trauma, survival, and rewriting the script when the world hands you someone else's lines.Bring tissues. Then bring receipts.RELATED LINKS• When the Baby Is Not OK (Book)• Jennifer's Website• Jennifer on LinkedInFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, visit outofpatients.show.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Critically Speaking
Anya Prince: Dangers of DTC Genetic Testing

Critically Speaking

Play Episode Listen Later Oct 7, 2025 38:12


In this episode, Therese Markow and Law Professor Anya Prince discuss the pros and cons of direct-to-consumer (DTC) genetic testing. DTC testing, which began in the 1990s and grew significantly by the 2010s, allows individuals to purchase genetic tests without a doctor's prescription. By 2021, 100 million people globally used DTC testing. Companies like 23andMe and Ancestry offer ancestry, health, and wellness information. However, concerns include data privacy, potential genetic discrimination, and the accuracy of health results. Professor Prince breaks down the 2023 data breach at 23andMe, discusses what DTC companies do with customer data (including DNA samples), and what third parties may be interested in the data collected by these companies.     Key Takeaways: There are hundreds of DTC genetic testing companies out there with a variety of levels of security measures. Some are going to be more secure than others.  Depending on which DTC company you use, some will destroy your genetic sample, but others may keep it indefinitely, potentially for future research and use. The US doesn't have any general data privacy protections, nor any broad genetic privacy action or protection. However, many states are beginning to pass general data protection laws.  There is no right or wrong answer for participating in genetic testing. It is something each needs to weigh the pros and cons for themselves and understand what is important to them and the risks they are willing to take.    "For the most part, DTC companies can do a lot with your data, and the customer doesn't have too much control over it. The main protection is a company's privacy policy." —  Anya Prince   Connect with Anya Prince: Professional Bio: https://law.uiowa.edu/people/anya-prince  Publications: https://library.law.uiowa.edu/anya-er-prince    LinkedIn: https://www.linkedin.com/in/anya-prince-3a06b171/    Connect with Therese: Website: www.criticallyspeaking.net Threads: @critically_speaking Email: theresemarkow@criticallyspeaking.net   Audio production by Turnkey Podcast Productions. You're the expert. Your podcast will prove it. 

The Gabby Reece Show
#344 Unlock Your Genetic Code: Kashif Khan on Personalized Health, Longevity & the #1 Nutrient You Need

The Gabby Reece Show

Play Episode Listen Later Oct 6, 2025 95:54


In this enlightening episode, Kashif Khan, co-founder of The DNA Company, discusses the intricate connection between genetics, health and wellness. Khan shares his personal health journey and explains how he went from battling multiple chronic diseases to becoming a pioneer in genetic research. He emphasizes the importance of understanding one's genetic makeup to navigate health challenges more effectively, touching on topics such as the role of the nervous system, diet, environment and the impact of ancestral genetic expressions. Beyond this, he and Gabby discuss how social connections can actually impact your health. Overall, this conversation covers actionable insights on how to tailor lifestyle choices, optimize health and manage stress based on individual genetic profiles. Check out this insightful conversation that will inspire you to dig deeper, make changes and better understand your body's individual needs.  Kashif Khan's Website: https://kashkhanofficial.com/ Follow Kashif Khan on Instagram: KashKhanOfficial For more on Gabby Instagram @GabbyReece TikTok @GabbyReeceOfficial The Gabby Reece Show Podcast on YouTube: https://www.youtube.com/@GabbyReece  The Gabby Reece Show podcast is Produced by Rainbow Creative (https://www.rainbowcreative.co/)  Thank You to Our Sponsors Timeline - My friends at Timeline are offering 20% off, just for my listeners. Head to timeline.com/gabby to get started. Ritual - Get 25% off your first month at ritual.com/GABBY Laird Superfood - High-quality ingredients paired with incredible taste. Use the code GABBY20 for 20% off your purchase at http://lairdsuperfood.com CHAPTERS 00:00 Understanding the Brain's Duality: Trauma vs. Gratitude 00:39 Introduction to the Guest: Kashif Khan 01:53 Kashif Khan's Personal Health Journey 02:47 The Role of Genetics in Health and Wellness 04:01 The Impact of Dopamine and Serotonin on Behavior 07:12 Genetic Traits and Their Influence on Health 12:00 The Importance of Sunlight and Circadian Biology 15:29 Cold and Heat Stress: Benefits and Adaptations 20:43 Longevity and Healthspan: The Role of Relationships 29:00 Genetic Testing and Personalized Health 34:29 Contrasting Personalities in the Workplace 35:10 Discovering Personal Traits and Leadership Styles 35:45 The Journey of Self-Discovery and Purpose 37:15 Applying Genetic Research to Real Life 38:40 The Gender Gap in Medical Research 40:26 Understanding Bioindividuality and Health 47:20 Genetic Testing and Personalized Healthcare 49:21 The Role of the Nervous System in Health 01:03:22 Epigenetics and Generational Trauma 01:06:32 Understanding Personal Identity and Survival Tools 01:07:39 Mapping the Mind and Discovering Self 01:08:59 Unlocking Superpowers and Managing Impulses 01:11:45 Invisible Factors Impacting Longevity 01:14:14 The Power of Real Food and Natural Remedies 01:17:56 Preventing Dementia and Alzheimer's 01:21:12 The Role of Genetics in Health and Performance 01:24:36 Empowerment Through Personalized Health 01:33:41 Balancing Health, Family, and Purpose Learn more about your ad choices. Visit megaphone.fm/adchoices

Real Pink
Episode 353: My Komen Why

Real Pink

Play Episode Listen Later Oct 6, 2025 18:03


This podcast is brought to you by Nature's Bounty. With a long-standing commitment to supporting women's health and wellness, Nature's Bounty is proud to partner with Susan G. Komen in the fight to end breast cancer. As we kick off National Breast Cancer Awareness Month, with eyes and ears on the breast cancer community, we are highlighting one of our passionate Komen donors to talk about why she chooses to support Susan G. Komen. Robin Eggert Elm is a long time 3-day supporter. She first started walking with her mom and sister in 2002 and now walks yearly with an ever-growing team of family and friends. Robin has spent more than 20 years in the health care industry and has worked with more than 100 mission-driven, not-for-profit organizations, including health systems,and service providers, senior housing and Catholic women religious congregations. Robin is truly passionate about walking as long as she can to continue fighting for a cure. Today, she's here to tell us about why she chooses to partner with Komen in this fight.

Creating a Family: Talk about Infertility, Adoption & Foster Care
When You Don't Know Your Child's Racial or Cultural Heritage - Weekend Wisdom

Creating a Family: Talk about Infertility, Adoption & Foster Care

Play Episode Listen Later Oct 4, 2025 15:10 Transcription Available


Click here to send us a topic idea or question for Weekend Wisdom.Question: We very recently brought home our second child through domestic infant adoption. We feel very fortunate, and our son is developing well; we are also settling into the new routine.  We matched with our Son's birth mother through a local agency, and unfortunately, she decided that she did not want to meet us. She gave no information about the biological father.  We know she was caucasian, but honestly, it is unclear whether our son is entirely caucasian or not. The pediatrician said it was a mystery, and he may be caucasian with a darker complexion, or biracial, some amount of Hispanic, black, or any other heritage. We want to do everything in our power to be informed, acknowledge, and celebrate any ethnic background that is presented, but short of doing a DNA ancestry service on a baby that is a few weeks old, I don't really know where to begin- I'd appreciate any guidance you have. Resources:Raising a Transracial or Multicultural ChildAdoptee VoicesEthical Issues in Genetic Testing in AdoptionGenetic Testing and Genealogy for AdopteesGenetic Testing for Adoptees – Is It Worth It?Support the showPlease leave us a rating or review. This podcast is produced by www.CreatingaFamily.org. We are a national non-profit with the mission to strengthen and inspire adoptive, foster & kinship parents and the professionals who support them.Creating a Family brings you the following trauma-informed, expert-based content: Weekly podcasts Weekly articles/blog posts Resource pages on all aspects of family building

OffScrip with Matthew Zachary
Introducing Standard Deviation EP1: The Impossible Climb

OffScrip with Matthew Zachary

Play Episode Listen Later Oct 2, 2025 9:33


This episode of Standard Deviation features Oliver Bogler in conversation with Dr Na Zhao, a cancer biologist caught in the crossfire of science, politics, and survival. Na's life reads like a brutal lab experiment in persistence.She grew up in China, lost her mother and aunt to breast cancer before she turned twelve, then came to the United States to chase science as both an immigrant and a survivor's daughter. She worked two decades to reach the brink of independence as a cancer researcher, only to watch offers and grants vanish in the political chaos of 2025.Oliver brings her story into sharp focus, tracing the impossible climb toward a tenure-track position and the human cost of a system that pulls the ladder up just as people like Na reach for it. This conversation pulls back the curtain on the NIH funding crisis, the toll on early-career scientists, and what happens when personal tragedy fuels professional ambition.Listeners will walk away with a raw sense of how fragile the future of cancer research really is, and why people like Na refuse to stop climbing.RELATED LINKSDr Zhao at Baylor College of MedicineDr Zhao on LinkedInDr Zhao's Science articleIndirect Costs explained by US CongressFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

ASCO Daily News
Identifying Young BRCA Carriers With Breast Cancer: Early Detection Can Lead to Better Prognosis

ASCO Daily News

Play Episode Listen Later Oct 2, 2025 14:21


Dr. Monty Pal and Dr. Matteo Lambertini discuss a compelling global study on the clinical behavior of breast cancer in young BRCA1 and BRCA2 carriers, the association of pre-diagnostic awareness of BRCA status with prognosis, and the importance of identifying healthy people who are at risk of carrying the BRCA1/2 pathogenic variants. TRANSCRIPT Dr. Monty Pal: Well, hello everyone, and welcome to the ASCO Daily News Podcast. I'm your host, Dr. Monty Pal. I'm a medical oncologist, professor, and vice chair of medical oncology at the City of Hope Comprehensive Cancer Center in Los Angeles. Now, when we think about genetic testing, whether for patients diagnosed with breast cancer or for other family members of them, it seems to be widely underutilized. Today, we're going to be discussing a recently published study in the Journal of Clinical Oncology that reported on the clinical behavior of breast cancer and specifically young BRCA1 and BRCA2 carriers, and the association of pre-diagnostic awareness of BRCA status with prognosis. I thought this was just a fascinating piece, and I honestly couldn't wait to have this conversation. It's a really compelling paper that highlights the importance of identifying healthy people who are at risk of carrying the BRCA1/2 pathogenic variants, and really the need for genetic counseling and testing to inform people about early detection that could lead to a better prognosis. I'm really delighted to welcome the study's lead author, Dr. Matteo Lambertini. He really needs no introduction. He's very well known in the breast cancer world for his amazing contributions to fertility in the context of breast cancer, to pregnancy in the context of breast cancer, and genetic testing. He's an associate professor at the University of Genova, and a breast cancer medical oncologist at the San Martino Polyclinic Hospital in Genova, Italy.  Dr. Lambertini, thank you so much for joining us today. Dr. Matteo Lambertini: Thank you very much, Dr. Pal. It's a great pleasure. Dr. Monty Pal: Oh, thanks. And just FYI, if you're listening in and you want to hear our disclosures, they're all listed at the transcript of this podcast.  So, I poured through this paper [Clinical Behavior of Breast Cancer in Young BRCA Carriers and Prediagnostic Awareness of Germline BRCA Status] yesterday, Dr. Lambertini, and first of all, congratulations on this study. This was a huge international multicenter effort, 4,752 patients. How did you pool all these patients with young breast cancer? Dr. Matteo Lambertini: Thanks a lot for the question. Yes, this was an effort made by several centers all over the world. The main idea behind the creation of this network that we have named as BRCA BCY Collaboration, was to get as many data as possible in a sort of niche patient population in the breast cancer field, meaning women diagnosed with breast cancer at the age of 40 years or younger, and all of them being BRCA carriers. We know that around, in the Western world, around 5% of breast cancer cases are being diagnosed under the age of 40 years, and among them around 10-15% are BRCA carriers. So, I would say it's a relatively rare patient population where we did not have a lot of evidence to support our choices in terms of counseling on treatment, prevention, and oncofertility as well. That was the idea behind the creation of this network that includes many centers. Dr. Monty Pal: Yeah. You know, what's so interesting about this is that you sort of draw this line between patients who have BRCA testing at the time of diagnosis and then BRCA testing earlier in their course and then leading to a diagnosis perhaps. And I think that's where really sort of the dichotomy in outcome sits. Can you maybe elaborate on this and tell us about timing of genetic testing in this study and what that meant ultimately in terms of prognosis? Dr. Matteo Lambertini: In this specific analysis from this large network, including almost 5,000 women with breast cancer diagnosed at the age of 40 years or younger and being a BRCA carrier, we looked specifically into the timing of genetic testing because this is a retrospective study and the criteria for inclusion are those that I have just mentioned, so diagnosis at a young age plus carrying germline BRCA pathogenic or likely pathogenic variant. In this analysis, we have looked into the time the patient has got the genetic testing and particular we focused on two populations: those that were diagnosed, knowing already to be a BRCA carrier, and those that got tested after being diagnosed with breast cancer. And the main findings from this analysis have been that knowing to be a BRCA carrier was associated with a lower stage at the time of diagnosis, meaning more T1 tumors, so a tumor less than 2 cm, more node-negative disease, and this translated into less aggressive treatment, so less often axillary dissection, less often use of chemotherapy and anthracycline-based chemotherapy. And even more importantly, we have seen a better overall survival for those patients that were diagnosed already knowing to be BRCA carriers as compared to those tested after breast cancer diagnosis. These results after adjusting for all the confounding, stage, treatment and so on, there was not significant anymore, meaning that it's not the timing of test per se that is probably leading to a better survival, but it is the fact that knowing to be a BRCA carrier would likely translate into having access to all the preventive measures that we have in this setting and this will translate into an overall survival benefit, so in terms of saving more lives in young BRCA carriers. Dr. Monty Pal: I think it's such an important point, and it's one that I think might sound implicit, right, but it needs to be proven, I think, through a study like this. You know, the fact that finding this early, identifying the mutation, doing enhanced screening, and so forth, is really going to lead to superior clinical outcomes. One of the things that I think many people puzzle over, including myself, is what to do? I personally occasionally will see BRCA altered patients in the context of prostate cancer. But that's a very different population of individuals, right? Typically older men. In young females with BRCA mutation, I guess there's a specific set of considerations around reproductive health. You'd already highlighted preventive strategies, but what sorts of things should we be talking about in the clinics once a patient's diagnosed and once perhaps their breast cancer diagnosis is established? Dr. Matteo Lambertini: Yes, exactly. Knowing to be a BRCA carrier has a lot of implications from prevention to treatment to survivorship issues including reproductive counseling. And this is important not only for the patient that has been diagnosed with breast cancer but also for all the family members that will get tested and maybe identify with this sort of genetic alteration before diagnosis of cancer. Why this is important is because we have access to very effective preventive measures, a few examples: MRI screening, which starts at a very young age and normally young women don't have an effective screening strategy outside the BRCA field. Also, primary preventive measures, for example, risk-reducing surgery. These women are known to have a high risk of breast cancer and high risk of ovarian cancer. So the guidelines are suggesting to undergo risk-reducing salpingo-oophorectomy at a young age, so 35 to 40 years in BRCA1 carrier, 40 to 45 years in BRCA2 carrier. And also risk-reducing mastectomy should be discussed because it is a very effective way to prevent the occurrence of breast cancer. And in some situations, including the setting that we are talking about, so young women with breast cancer, BRCA carrier, also risk-reducing mastectomy has shown to improve overall survival.  On the other side, once diagnosed with breast cancer, nowadays knowing to be or not a BRCA carrier can make a difference in terms of treatment. We have PARP inhibitors in the early setting, in the adjuvant setting as well as in the metastatic setting. And in terms of survivorship implication, one of the critical aspects for young women is the oncofertility care which is even more complicated when we talk about BRCA carriers that are women candidates for gynecological surgery at a very young age. So this sort of counseling is even more complicated. Dr. Monty Pal: One of the other things, and this is subtle in your paper and I hope you don't mind me bringing it up, is the difference between BRCA1 and BRCA2. It really got me thinking about that because there are differences in phenotype and manifestation. Do you mind just expanding on that a little bit for the audience because I think that's a really important reminder that you brought up in the discussion? Dr. Matteo Lambertini: The difference between BRCA1 and BRCA2 carriers has been known that there are different phenotypes of breast cancer that are more often diagnosed in these two different populations. Normally BRCA1 carriers have a higher likelihood to develop a triple negative breast cancer as compared to BRCA2 carriers, more likely to develop a hormone receptor-positive HER2-negative disease. In this study, again, a specific population of young women with breast cancer, we have seen the same findings, mostly triple negative disease in BRCA1 carrier, mostly luminal-like disease in BRCA2 carrier. But what's novel or interesting from this study is to look also at the age at the time of diagnosis of this disease. And particularly in BRCA1 carriers, we should be sort of more careful about diagnosis of breast cancer and also other primary tumors including ovarian cancer because the risk of developing these malignancies is higher even at a younger age as compared to BRCA2 carriers. And this has implications also in the primary and secondary prevention that we were talking about earlier. Dr. Monty Pal: Oh, interesting. I guess the fundamental question then from your paper becomes, how do we get at the right patients for screening for BRCA1 and BRCA2? And I realize our audience here is largely oncologists who are going to be listening to this podcast, oncology providers, MDs, nurses, etc. But maybe speak for a moment to the general practitioner. Are there things that, for instance, a general practitioner should be looking for to say, “Wait a minute, this patient's high risk, we should consider BRCA1, BRCA2 testing or germline screening”? Dr. Matteo Lambertini: Yes, it's a very important question for the breast cancer community. After the updated ASCO guideline, the counseling is way easier because right now the age cutoff goes up to 65 years, meaning that all the patients diagnosed with breast cancer below the age of 65 years should be tested these days. And then above the age of 65, there are different criteria like triple-negative disease or family history. From a general practitioner standpoint, it's of course a bit more difficult, but knowing particularly the family history of the person that they have in front will be crucial to know if there are cases of breast cancer diagnosed at a young age, maybe triple-negative cases, knowing cases of ovarian cancer in first-degree relatives or pancreatic cancer in first-degree relatives, and of course cases of prostate cancer as well. So, I would say probably mostly the family side will be important from a general practitioner perspective.  From an oncology one, the other point that I think is important to stress also based on the data that we have shown in this publication is that having a case of breast cancer known to carry a BRCA pathogenic or likely pathogenic variant. It means that all the people around this case should get tested and if found to be BRCA carrier and healthy carrier, these people should also undergo the primary and secondary prevention strategies because this is very critical also to improve their outcomes and try to avoid the developing of breast or ovarian cancer, but also in the case of diagnosis of this disease, a diagnosis at an earlier stage, as we have seen in this paper. Dr. Monty Pal: Brilliant. I'm going to diverge from our list of questions here and close by asking a question that I have at the top of my mind. You're very young. I know our podcast listeners can't see you, but you're very, very young. Dr. Matteo Lambertini: Thank you. Thank you for that. Not so young but yeah. Dr. Monty Pal: You have nearly 300 papers. Your H-index is 67. You've already made these seminal contributions, as I outlined it from the outset, regarding fertility, regarding use of GnRH analogs, regarding pregnancy and breast cancer. What are you studying now? What are you really excited about right now that you're doing that you think might potentially be practice changing? Give us a little teaser. Dr. Matteo Lambertini: Yeah. Thanks a lot, Dr. Pal. Receiving this compliment from you is fantastic. So, thanks a lot for that. From my side, in terms of my research, I've been interested in the field of breast cancer in young women since the start of my training. I've had very good mentors from Italy, from Europe, from the U.S. I'm still interested in this field, so I think we still have a lot to learn to try to improve the care of young women with breast cancer. For example, the oncofertility care, which is something I worked a lot over the past years. Now with all the new treatment options, there's a sort of new chapter of oncofertility counseling. So, what's the impact of immunotherapy? What's the impact of the new targeted agents?  More on the genetic aspects, now we know that there's not only BRCA1 or BRCA2. There are a lot of other different genes that may increase the risk of breast cancer and other malignancies. And also for these genes, we really don't have a lot of evidence to counsel women on prognosis, treatment, prevention strategy. So we need to learn way more for this special patient population that are quite rare, and so we really need a multicenter academic effort to try to give some evidence in this field. Dr. Monty Pal: Yeah. It's tough because these are rare circumstances, but, you know, I think that you've done really well to sort of define some collective experiences that I think really define therapy. I mean, I just remember when I was in training 25 years ago, just reading through textbooks where all the experience around breast cancer and pregnancy was really just very sort of anecdotal almost, you know? And so it's great to see that the state of the science has moved forward.  Well, gosh, I really enjoyed our conversation today. I think your study really reminds us how powerful genetic information is in terms of improving outcomes. And, you know, hopefully this will lead some individuals to perhaps test more broadly in appropriate settings. So, thank you so much, Matteo, for joining us today with your fantastic insights on the ASCO Daily News Podcast. Dr. Matteo Lambertini: Thank you very much, Dr. Pal. It's a real pleasure. Dr. Monty Pal: And thanks to our listeners too. You'll find a link to Dr. Lambertini's study in the transcript of this episode. Finally, if you value the insights that you heard today on the ASCO Daily News Podcast, please rate, review, and subscribe wherever you get your podcasts. Thanks a ton. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Find out more about today's speakers:    Dr. Sumanta (Monty) Pal  @montypal  Dr. Matteo Lambertini @matteolambe   Follow ASCO on social media:     @ASCO on Twitter    ASCO on Bluesky   ASCO on Facebook     ASCO on LinkedIn     Disclosures:    Dr. Monty Pal:   Speakers' Bureau: MJH Life Sciences, IntrisiQ, Peerview  Research Funding (Inst.): Exelixis, Merck, Osel, Genentech, Crispr Therapeutics, Adicet Bio, ArsenalBio, Xencor, Miyarsian Pharmaceutical  Travel, Accommodations, Expenses: Crispr Therapeutics, Ipsen, Exelixis  Dr. Matteo Lambertini: Consulting or Advisory Role: Roche, Novartis, Lilly, AstraZeneca, Pfizer, MSD, Exact Sciences, Gilead Sciences, Seagen, Menarini, Nordic Pharma Speakers' Bureau: Takeda, Roche, Lilly, Novartis, Pfizer, Sandoz, Ipsen, Knight Therapeutics, Libbs, Daiichi Sankyo, Gilead Sciences, AstraZeneca, Menarini, AstraZeneca, Menarini Research Funding (Inst.): Gilead Sciences Travel, Accommodations, Expenses: Gilead Sciences, Daiichi Sankyo Europe GmbH, Roche

TODAY
TODAY, Pop Culture & Lifestyle October 1: Sheryl Crow's Breast Cancer Journey | The Importance of Genetic Testing

TODAY

Play Episode Listen Later Oct 1, 2025 14:58


Legendary music star Sheryl Crow shares her personal breast cancer story and how she's become a leading voice for early detection. Also, to kick off Breast Cancer Awareness Month, our TODAY team highlights the importance of genetic testing and screenings with a plaza event where hundreds sign up for free kits. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

OffScrip with Matthew Zachary
Sorry, Your Awareness Campaign is Showing

OffScrip with Matthew Zachary

Play Episode Listen Later Sep 30, 2025 43:22


Katie Henry has seen some things. From nonprofit bootstraps to Big Pharma boardrooms, she's been inside the machine—and still believes we can fix it. We go deep on her winding road from folding sweaters at J.Crew to launching a vibrator-based advocacy campaign that accidentally changed the sexual health narrative in breast cancer.Katie doesn't pull punches. She's a born problem solver with zero tolerance for pink fluff and performative empathy. We talk survivor semantics, band camp trauma, nonprofit burnout, and why “Didi” is the grandparent alter ego you never saw coming.She's Murphy Brown with a marimba. Veronica Sawyer in pharma. Carla Tortelli with an oncology Rolodex. And she still calls herself a learner.This is one of the most honest, hilarious, and refreshingly real conversations I've had. Period.RELATED LINKS:Katie Henry on LinkedInKatie Henry on ResearchGateLiving Beyond Breast CancerNational Breast Cancer CoalitionFEEDBACK:Like this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Real Pink
Episode 352: Real Talk: Bringing Care To The Black Community

Real Pink

Play Episode Listen Later Sep 29, 2025 27:18


Breast cancer affects everyone differently. African American and Black women are 40% more likely to die from breast cancer than white women. Biology and genes are driving factors, but we cannot overlook the fears and concerns women in these communities have when it comes to seeking medical care. Mistrust, bad experiences and deep-rooted bias are all standing in the way of saving more lives from breast cancer. Today, we're joined by Jessica Williams, a leading and powerful voice in the Black community in South Florida. And Gil Zepeda, the Development Manager of Susan G. Komen in Florida. Jessica and Gil just took part in an event that brough mobile mammography to an underserved neighborhood in South Florida.

Bowel Sounds: The Pediatric GI Podcast
Amber Hildreth - Genetic Testing for Children With GI Disorders

Bowel Sounds: The Pediatric GI Podcast

Play Episode Listen Later Sep 22, 2025 43:42


In this episode of Bowel Sounds, hosts Dr. Peter Lu and Dr. Jason Silverman talk to Dr. Amber Hildreth, pediatric gastroenterologist and transplant hepatologist at Rady Children's Hospital and Assistant Professor at the University of California San Diego. She is also a clinician scientist at the Rady Children's Institute for Genomic Medicine. We discuss how genetic testing is transforming the way we care for children with rare GI and liver diseases.Learning objectivesRecognize key differences between various types of genetic testing.Discuss several applications of genetic testing in care for children with GI disorders.Understand the role of the genetic counselor in integrating genetic testing into GI practice.Support the showThis episode may be eligible for CME credit! Once you have listened to the episode, click this link to claim your credit. Credit is available to NASPGHAN members (if you are not a member, you should probably sign up). And thank you to the NASPGHAN Professional Education Committee for their review!As always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Check out our merch website!Follow us on Bluesky, Twitter, Facebook and Instagram for all the latest news and upcoming episodes.Click here to support the show.

Real Pink
Episode 351: The Language of Care: Culturally Responsive Breast Health

Real Pink

Play Episode Listen Later Sep 22, 2025 17:31


During Hispanic Heritage Month, we reflect not only on cultural pride but also on the urgent health challenges facing the Latino community. Breast cancer is the most commonly diagnosed cancer among Latinas, and yet barriers such as language, limited access to care and cultural stigma often prevent women from receiving the support they need. In this episode of Real Pink, we're joined by Dr. Laura Logie of Nueva Vida, a trusted partner of Susan G. Komen® and a member of the ShareForCures® Alliance. Together, we'll explore how culturally responsive care can transform the breast cancer experience, break down barriers and ensure that Latinas feel seen, heard and supported every step of the way.

OffScrip with Matthew Zachary
The Uncensored, Unapologetic Olivia Battinelli

OffScrip with Matthew Zachary

Play Episode Listen Later Sep 16, 2025 42:55


What happens when you hand a mic to the most extroverted, uncensored Gen Z career coach in New York? You get Olivia Battinelli—adjunct professor, student advisor, mentor, speaker, and unfiltered truth-teller on everything from invisible illness to resume crimes.We talked about growing up Jewish-Italian in Westchester, surviving the Big Four's corporate Kool-Aid, and quitting a job after 7 months because the shower goals weren't working out. She runs NYU Steinhardt's internship program by day, roasts Takis and “rate my professor” trolls by night, and somehow makes room for maple syrup takes, career coaching, and a boyfriend named Dom who sounds like a supporting character from The Sopranos.She teaches kids how to talk to humans. She's allergic to BS. And she might be the most Alexis Rose-meets-Maeve Wiley-mashup ever dropped into your feed. Welcome to her first podcast interview. It's pure gold.RELATED LINKS:Olivia Battinelli on LinkedInOlivia's Liv It Up Coaching WebsiteOlivia on InstagramNYU Steinhardt Faculty PageFEEDBACK:Like this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

OffScrip with Matthew Zachary
Miss Diagnosed: Sophie Sargent

OffScrip with Matthew Zachary

Play Episode Listen Later Sep 16, 2025 43:24


Sophie Sargent walked into the studio already owning the mic. A pandemic-era media rebel raised in New Hampshire, trained in Homeland Security (yep), and shaped by rejection, she's built a career out of DM'ing her way into rooms and then owning them. At 25, she's juggling chronic illness, chronic overachievement, and a generation that gets dismissed before it even speaks.We talk Lyme disease, Lyme denial, and the healthcare gaslighting that comes when you “look fine” but your body says otherwise. We dive into rejection as a career accelerant, mental health as content porn, and what it means to chase purpose without sacrificing identity. Sophie's a former morning radio host, country music interviewer, and Boston-based creator with a real voice—and she uses it.No fake podcast voice. No daddy-daughter moment. Just two loudmouths from different planets figuring out what it means to be seen, believed, and taken seriously in a system designed to do the opposite.Spoiler: She's smarter than I was at 25. And she'll probably be your boss someday.RELATED LINKSSophie on InstagramSophie on YouTubeSophie on LinkedInMedium article: “Redefining Rejection”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Huberman Lab

Play Episode Listen Later Aug 18, 2025 143:29


My guest is Dr. Sergiu Pașca, MD, professor of psychiatry and behavioral sciences at Stanford University. We discuss the biology and genetics of autism, why autism diagnoses are increasing and recent progress in using stem cells to understand and treat profound autism and other brain disorders. Dr. Pașca explains “organoids and assembloids”—human stem cell–derived tools he pioneered to study, treat and cure complex brain diseases. We also discuss ethical and safety issues with using gene editing and stem cells in humans. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman Helix: https://helixsleep.com/huberman BetterHelp: https://betterhelp.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00) Sergiu Pașca (02:08) Autism Spectrum Disorder, Incidence, Genetics (07:16) Is Autism More Common in Males? (09:35) Sponsors: David & Helix Sleep (11:56) Eye Contact in Babies, Fever; Proposed Causes of Autism; Genes (18:48) Genetic or Idiopathic Autism Diagnoses, Timothy Syndrome (21:37) Rise in Autism Diagnoses (26:46) Cause, Correlation & Neurological Disease; Schizophrenia, Do Vaccines Cause Autism? (31:34) Global Increase in Autism; Gene Therapy, CRISPR, Follistatin (41:05) Sponsors: AG1 & BetterHelp (43:41) Stem Cells, Ethics, Yamanaka Factors, Human Stem Cell Models (52:03) Umbilical Stem Cells; Stem Cell Injections & Dangers, Autistic Kids (59:30) Organoids, Modeling Brain Development, Intrinsic Development Timer (1:12:22) Assembloids, Brain Cell Migration & Circuit Formation, Self-Organization (1:21:22) Four-Part Assembloid, Sensory Assembloid, Pain Conditions (1:25:45) Sponsor: Function (1:27:33) Future Medical Therapies, Cell Banking, Immortalize Tissues, Rejuvenate Cells (1:34:56) Assembloids & Ethics, Importance of Nomenclature, Science Collaboration & Self-Correction (1:45:38) Cell Transplantation & Ethics, Timing (1:55:05) Genetic Testing for Parents, Genetic Penetrance (2:02:36) Assembloids, Timothy Syndrome, Epilepsy, Schizophrenia, Dystonia (2:14:30) Scientific Career, Walking, Art, Medical School (2:20:44) Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices