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In this episode, Dr. Luca Pellegrini is interviewed by Olivia Hillier, with narration by Andrew Cao, from the University of Ottawa. Dr. Pellegrini is a new professor in the department of Biochemistry, Microbiology, and Immunology and is an expert on mitochondria and inter-organelle contacts. He joins us to discuss his team's most recent paper, published in Cell Reports (https://doi.org/10.1016/j.celrep.2021.108873). This publication describes his team's discovery of the “wrappER”, a microscopic superhero in your body that plays a vital role in keeping you in top shape. Dr. Pellegrini takes us through the history of inter-organelle contacts research, the intriguing results detailed in his paper, and the broader implications of his findings to human health. Learn more: https://www.pellegrinilab.com/ 0:27 | Podcast team introduction0:42 | Meet the wrappER, the cloak that safeguards your metabolic health.2:02 | Meet Dr. Luca Pellegrini, the founder of the wrappER.3:00 | How did Dr. Pellegrini come to study the wrappER?3:46 | Why does Dr. Pellegrini like history so much?4:41 | When did researchers start to consider how contacts between organelles may be important?5:58 | Diseases related to defects in inter-organelle contacts.6:48 | What you need to know about Anastasia et al., 2021: the paper that discovered and defined the wrappER.8:12 | The wrappeR's structure is like a burrito.8:43 | Are all mitochondria wrapped by the wrappER?9:01 | The wrappER is not limited to liver cells.9:38 | What else can the wrappER wrap?10:12 | Dynamics of the wrappER and mitochondria.11:32 | How long did it take to make these discoveries of the wrappER?11:44 | The team behind the discovery.12:40 | What the wrappER can teach us about how our bodies regulate fat.13:18 | The wrappER and treatments for fat-related diseases and disorders.13:55 | Dr. Pellegrini's plans as a new profressor and principal investigator at the University of Ottawa.14:22 | Wrapping up: thank you to Dr. PellegriniPodcast by Andrew Cao (Narrator and Post-Production), Olivia Hillier (Interviewer), Olivia Sommers (Producer), & Anna Wang (Writer-Editor).Music:“The Launch” by Chronox (https://freemusicarchive.org/music/Chronox_2/) This song can be found on the Free Music Archive (https://freemusicarchive.org/music/Chronox/Voyager/Chronox_-_01_-_The_Launch/)“Nocturnal (BGM)” by LEMMiNO (https://www.lemmi.no/) “Thannoid” by Blue Dot Sessions (https://www.sessions.blue/) “Are We Loose Yet” by Blue Dot Sessions (https://www.sessions.blue/) “Here” by Hyson (https://iamhyson.bandcamp.com/)
In the third and final episode of The Battle Over You: AMP v. Myriad, KCSB's Joyce Chi discusses the Supreme Court's landmark ruling and where the decision stands today. This story uses the following music: Thannoid, Soothe, and Powder Room by Blue Dot Sessions, and Buoyancy by Chad Crouch. It features audio from CSPAN and the Oyez Project. Special thanks to Erin Nordquist, Nicole Cribioli, Rowan Walls, Cindy Zhao, and KJ Smith, as well as Drs. Roger Klein, Uta Francke, Krystal Redman, and Mimi Wan.
In this Episode of Learner Journeys, Bastian speaks with Justin Sitron. Justin is associate dean at Widener University's College of Health and Human Services. His work focuses on culturally responsive sexuality education and community-based participatory research. He teaches health professionals how to adapt to their clients and understand their diverse sexological worldviews. To know more about him, head over here! Credits: Learner Journeys is created and hosted by Bastian Küntzel Cover Illustration by Michal Wronski Cover Design by Anna Pomichowska Music Credits: Epic Cinematic by Scott Holmes Cases to Rest by Blue Dot Sessions (www.sessions.blue) Thannoid by Blue Dot Sessions (www.sessions.blue) Alchemical by Blue Dot Sessions (www.sessions.blue) Pickers by Blue Dot Sessions (www.sessions.blue) Silk and Silver by Blue Dot Sessions (www.sessions.blue) Curiously and Curiously by Blue Dot Sessions (www.sessions.blue) Headlights Mountain Road by Blue Dot Sessions (www.sessions.blue) Soothe by Blue Dot Sessions (www.sessions.blue) Tidal Foam by Dot Sessions (www.sessions.blue) UpUpUp and Over by Blue Dot Sessions (www.sessions.blue)
Grab a parasol, put your monkey on a leash, and come spend Sunday in the Park with George, exploring how a canvas this monumental and as frozen as Dippin' Dots can help us better understand the world in his day, in Cameron Frye's, and in our own. See the images: https://bit.ly/2L0qPCg Music used: Django Reinhardt, “Django's Tiger” The Andrews Sisters, "Bei Mir Bist Du Schoen" The Blue Dot Sessions, “Feisty and Tacky,” “Stack Me Up,” “Base Camp,” “Thannoid,” “PolyCoat,” “Slow Rollout” Joe Dassin, “Les Champs-Elysees" Support the show: www.patreon.com/lonelypalette Episode sponsor: www.evanblanch.com/lonely
The Lonely Palette is currently the podcast-in-residence at the Museum of Fine Arts, Boston, and we're partnering up to bring the museum to you during its closure due to Covid-19 by spotlighting both the rock star and the lesser-known objects from the museum's permanent collection. So relax into your PJs, put your feet up, and let's #MuseumFromHome together. This week: it isn't 17th century Dutch art if we're not going so deep into Rembrandt's soul and so close to the meticulous details of his virtuosic portraiture that we make the guards nervous. See the images: http://www.thelonelypalette.com/episodes/2019/5/23/episode-39-rembrandt-van-rijns-portrait-of-aeltje-uylenburgh-1632 Music used: Django Reinhardt, “Django's Tiger” The Andrews Sisters, "Bei Mir Bist Du Schoen" The Blue Dot Sessions, “Lovers Hollow” “Tailrunner,” “Entwined Oddity,” “Lupi,” “Thannoid,” “Camp Fermin” Joe Dassin, “Les Champs-Elysees" Support the show! www.patreon.com/lonelypalette
Medicaid is one of the largest social welfare programs in the United States. With over 70 million people enrolled, it covers 20 percent of the US population. Though the program is federal, it’s implemented by the state and some states offer generous benefits while others do not. Professor Jamila Michener argues these disparities are actually having an effect on democratic citizenship. Her research shows that when Medicaid expands, more people vote, and when it contracts (or there’s a narrower scope of benefits) then people are less likely to vote. Jamila Michener is an assistant professor at Cornell University. Her book is Fragmented Democracy: Medicaid, Federalism, and Unequal Politics (Cambridge University Press, 2018) Read the episode transcript Music: Vittoro and Thannoid by Blue Dot Sessions / Licensed under Creative Commons Attribution
How does a potential drug discovered in the lab ultimately end up in people? We tackle this question in the context of exciting gene-modifying therapies called antisense oligonucleotides (ASOs). In this episode, we speak with Dr. Tim Miller to break down the science behind ASOs and learn more about his work in finding a cure for a genetic form of amyotrophic lateral sclerosis (ALS). This episode was written and produced by Nancy Cai, Devika Nair, and Arja Ray. Music used in this episode: “Thannoid”, “Bundt”, “Lupi”, “Partly Sage”, “Beignet”, “Trailrunner”, “Game Hens”, “Lord Weasel”, “The Zeppelin”, “Dorica”, “Our Fingers Cold”, “Gaena” by Blue Dot Sessions For more information about spinal muscular atrophy (SMA), check out the spinal muscular dystrophy association website: https://www.mda.org/disease/spinal-muscular-atrophy. There is also this great animation that shows how the Spinraza (nusinersen) ASO works in the body: https://www.spinraza.com/en_us/home/taking/how-spinraza-works.html. To read the results from the first ASO for Huntington’s disease, check out the New England Journal of Medicine article here: https://www.nejm.org/doi/full/10.1056/NEJMoa1900907?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed.
It isn't 17th century Dutch art if we're not going so deep into Rembrandt's soul and so close to the meticulous details of his virtuosic portraiture that we make the guards nervous. See the images: http://www.thelonelypalette.com/episodes/2019/5/23/episode-39-rembrandt-van-rijns-portrait-of-aeltje-uylenburgh-1632 Music used: Django Reinhardt, “Django's Tiger” The Andrews Sisters, "Bei Mir Bist Du Schoen" The Blue Dot Sessions, “Lovers Hollow” “Tailrunner,” “Entwined Oddity,” “Lupi,” “Thannoid,” “Camp Fermin” Joe Dassin, “Les Champs-Elysees" Support the show! www.patreon.com/lonelypalette Thanks to our episode sponsors: www.thegreatcourses.com/lonely www.visualartspassage.com
Hussein Rashid of Barnard / Columbia discusses the importance of thinking critically about news, information, and stories relating to the Middle East. We also highlight five activities you can do to promote media literacy in your classrooms. Learn more at www.primarysource.org/podcasts Music credits: "Kim Arar" by Wind of Anatolia "Sueur" by Monplaisir "Waterbourne" by Blue Dot Sessions "Thread of Clouds" by Blue Dot Sessions "Tower of Mirrors" by Blue Dot Sessions "Spins and Never Falls" by Blue Dot Sessions "Filing Away" by Blue Dot Sessions "Thannoid" by Blue Dot Sessions "-Yesilim" by Turku
MACEO HERNANDEZ is a professional Taiko drummer whose passion for the ancient Japanese form of percussion began in the 7th grade. Despite having no rhythm or musical experience, young Maceo was determined to play Taiko, leading him on a life-changing journey to Japan and inspiring a documentary film. (51:11) EPISODE NOTES: MACEO HERNANDEZ was in the 7th grade when he experienced an epiphany while listening to a Japanese Taiko group performing at a family friend’s wedding. MACEO: “You could really feel the impact and the vibration of these Taiko drums. And it just blew me away. I went up to them and helped them load these drums into their car. I just wanted to touch and feel these drums. I knew then I wanted to play these drums, even though I had no rhythm. I never drummed in my life. I never played an instrument. But the Taiko drum drew me to want to play it, even though I didn’t know anything about it.” Having a Mexican-American teenager dedicate himself to the ancient Japanese form of percussion made Maceo something of a curiosity to many in LA’s Japanese-American community, including documentary filmmaker John Esaki. John produced and directed a film called “Maceo: Demon Drummer From East LA.” JOHN: “Here was a young person who was not Japanese or Japanese-American and he was really so passionate about playing the Taiko drum. It just fascinated me that someone outside of the Japanese culture would have this interest. With Maceo, I always thought he was very genuine about following his interest. He found something that gave him great joy to participate in and he was going to follow that path to see where it led.” Where it led was to Japan. At the age of 15, Maceo was recruited by Ondekoza, a celebrated and highly athletic Taiko troupe that performs concerts around the world. MACEO: “One of the main things we did in Ondekoza was run. We were very famous for running a marathon and then performing Taiko afterwards. So running was a big part of our daily life. We’d wake up in the morning and we’d run. In the afternoon, we’d run again. Part of this training was to build up stamina for the shows that we would perform. One day, I was running and this truck was carrying metal pipes. They rolled off and landed on me. I woke up in the hospital after a seven-hour operation. A week later, they amputated my left leg. And there began a new journey.” The first steps of Maceo’s new journey began with long, dark nights far away from home in a Japanese hospital. He says it was difficult for him to reconcile his newly altered physical form with his intense desire to be a professional drummer. But over the next couple months, Maceo’s Taiko drum helped him find his way out of the darkness. MACEO: “It might sound strange, but I used to talk to my drum and try to have a communication with it on a different level than other members had. Hitting this drum, gave me all this energy back and gave me the will to continue on with my goals. It pretty much took over me and helped me not be sad all the time and not feel discouraged. This drum was my friend. It was my therapy.” Less than a year after his accident in Japan, Maceo Hernandez returned to the United States and ran the New York City Marathon on a prosthetic leg. Moments after crossing the finish line, fellow members of Ondekoza carried him to a nearby stage where he performed a 15-minute Taiko solo. The spectacular moment epitomized Ondekoza’s principle of Sogakuron – that running and drumming are one, and a reflection of the drama and energy of life. BP Many thanks to the Blue Dot Sessions for the opening and closing music featured in this episode royalty free through Creative Commons licensing: 1. "Cases for Rest" by Blue Dot Sessions - sessions.blue/sessions/ 2. "Thannoid" by Blue Dot Sessions - sessions.blue/sessions/
Tania introduces Terror Management Theory and speaks to her mom about her relationship with death and about their mutual love for the ocean. You also hear from Hannah, who's all the way in New York, Tania's partner, Ramin, as well as from friends who share their own thoughts on death and love. Music in the order played: - Thannoid by Blue Dot Sessions - Out of the Fresh Night by Kaela Drew licensed under CC BY-NC 4.0 - Equatorial Lines by Hayvanlar Alemi licensed under CC BY-NC-ND 4.0 - Collapse into Innocence by Siddhartha licensed under CC BY 4.0 - Equatorial Lines by Hayvanlar Alemi licensed under CC BY-NC-ND 4.0 - Backward Steps by Unheard Music Concepts licensed under CC BY 4.0 - La Luna y El Loro by Tomás de San Julián - Underestimate the Ancestors by Triad licensed under CC BY 4.0 - As Nihilism Gives Way To Existentialism by Nihilore licensed under CC BY 3.0 - Tethered by Nctrnm licensed under CC BY 4.0 - En Route (ou Enfin! Le Défilé Capsule de Temps va au Centre de Contrôle) by Monroeville Music Center licensed under CC BY 3.0 - Ey Sareban by Mohsen Namjoo - Gracias a la Vida by Mercedes Sosa - Thannoid by Blue Dot Sessions