BEaTS Research Radio's Podcast

Deyanira Hdez. de la Universidad de Ottawa, habla con el Dr. Sergio Alberto Bernal Chávez, Profesor del departamento de Ciencias Químico Biológicas de la Universidad de las Américas, Puebla, y miembro del Sistema Nacional de Investigadores, nivel 1. El Dr. Bernal es Químico Farmacéutico Biólogo con maestría y doctorado en Ciencias Químicas por la UNAM. Su investigación se centra en la aplicación de nanotecnología para el desarrollo de productos cosméticos innovadores. En el episodio de hoy el Dr. brneal dsmitificará ideas sobre los bloqueadores solares.https://www.udlap.mx/profesores/Sergio-Alberto-Bernal-Chavez

Joyce Lu from the University of Ottawa interviews Dr. Céline Aguer. Dr. Aguer is an assistant professor at McGill University in the Department of Physiology and principal investigator in her muscle metabolism laboratory at the Institut du Savoir Montfort in Ottawa. In this episode, Dr. Aguer shares her research on how bisphenol A (BPA), an environmental pollutant, disrupts muscle metabolism. This episode also features additional commentary by Dr. Ella Atlas, adjunct professor at the Department of Biochemistry, Microbioloy and Immunology and Health Canada Research Scientist on environmental pollutants.Learn moreDr. Céline Aguer: https://www.uottawa.ca/faculty-medicine/dr-celine-aguerDr. Ella Atlas: https://www.uottawa.ca/faculty-medicine/dr-ella-atlas0:16 | BEaTS, Host introduction, and Background information.0:55 | Introduction to Dr. Aguer1:26 | How Dr. Aguer started research on pollutants and muscle metabolism,2:54 | Current issues with BPA exposure and why studying BPA is important?5:51 | Special Guest Dr. Ella Atlas Introduction6:11 | Dr. Atlas' insights on BPA alternatives and avoidance8:05 | How BPA can cause insulin resistance in muscle cells11:15 | Other potential health impacts of BPA exposure12:22 | Future Studies with the Aguer Lab14:08 | Closing RemarksSoundtrack by The Underground Drive. All rights reserved. Listen more:https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmRJoyce Lu (Podcast Host), Emily Wood (Writer/Editor), Ernest Ngou (Audio Master), Angela Wang (Producer)

Sahib Moga from the University of Ottawa interviews Dr. Jean-François Couture. Dr. Couture is a Full Professor and Chair in the Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa. He has published over 90 papers in prestigious journals and is a leading structural biology and epigenetics expert. In this episode, Dr. Couture shares his research on the role of a non-canonical zinc finger in stabilizing Cfp1's integration into the H3K4 methyltransferase complex COMPASS and its implications for epigenetic signaling and cancer biology.Learn more: http://jfclab.ca/0:05 | BEaTS and host introduction1:00 | Introduction to Dr. Couture1:58 | Introduction to epigenetics and structural biology5: 55 | COMPASS complex and its role8:14 | Novel zinc finger discovery12:20 | Future treatments and drug development 13:15 | ConclusionSoundtrack by The Underground Drive. All rights reserved. Listen more:https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmRDaniel Nguyen (Producer), Sahib Moga (Host), Ryan Zammar (Content Writer), Francesco Cortese (Post-Production)

Iman Kashif from the University of Ottawa interviewed Dr. Barbara Vanderhyden, a senior scientist in ovarian cancer research and a professor at the University of Ottawa. In this insightful episode, Dr. Vanderhyden discusses her groundbreaking research pertaining to how immune regulator NLRC5 can reshape the tumor microenvironment and increase T-cell reactivity to better recognize and respond to cancer cells. She explains the mechanisms of immune evasion in ovarian cancer and discusses how her work could pave the way for novel therapeutic approaches. Learn more: https://www.ohri.ca/profile/vanderhydenlab/profile1:47 | Immune Evasion and NLRC5.4:49 | Clinical Applications of NLRC5.6:28 | Combination Therapy with NLRC5.9:23 | Tumor Adaptation Challenges. 12:26 | Advice for Early Career Professionals.Music Credit/Copyright information: Copyright free, Youtube video: “DEATH NOTE - L THEME SONG (RIFTI BEATS REMIX) [No Copyright Music]”. Account: Kingdom Power Music. Published January 18, 2021. https://www.youtube.com/watch?v=AkFHNQELp3Y&ab_channel=KingdomPowerMusicIman Kashif (Host, Audio Master), Jacqueline Aoun (Producer), Aaya Mahdi (Content Writer), Shreya Padhy (Content Writer)

Serena George, a student from the University of Ottawa, interviewed Dr. Melissa Fernandez, an assistant professor at the School of Nutrition Sciences at the University of Ottawa. Her research focuses on understanding the impacts of digital food environments on health and nutrition, with a particular interest in food literacy, eating practices, dietary intake, and mental health. In this episode, Dr. Fernandez gives insights into the research behind one of her studies that suggests that improving cooking skills and reducing processed food use may support healthier diets and overall well-being. Following this, Serena sits down with Nicholas Goulet, a Ph.D. candidate in the School of Human Kinetics at the University of Ottawa, who shares his perspective on Dr. Fernandez's research and the insights discussed in the interview. 00:19 | Main guest introduction00:46 | What inspired Dr. Fernandez to focus on nutrition research01:22 | Main findings of the study, 01:58 - Dr. Fernandez on her research study04:18 | Food agency and impact of cooking skills, 05:38 Impact of Socioeconomic background, education, and culture07:46 | Cooking skills and mental health09:34 | Future research recommendations11:39 | Message to listeners and general public13:29 | Input from PhD candidate Nicholas Goulet14:45 | Closing remarks. Learn more: https://www.uottawa.ca/faculty-health-sciences/nutrition/our-professors/melissa-a-fernandez.  Music credits: Guitar Beat Intro / Outro 0128 by TuesdayNight on Pixabay.com (copyright-free) Producer: Svitlana Demchenko, Show Host: Serena George, Writer editor: Nohadra Jeorje, Audio master: Anna Pawelko 

Giselle Joseph of the University of Ottawa interviews Dr. Deborah M. Siegal of the Ottawa Hospital Research Institute about how a simple change in blood collection practices in ICUs could significantly improve patient care. Dr. Siegal is a hematologist, clinician-scientist at the Ottawa Hospital Research Institute, and Associate Professor of Medicine at the School of Epidemiology and Public Health at the University of Ottawa.Learn more: https://www.ohri.ca/profile/dsiegal0:06 | Introduction0:56  | Motivation behind using small-volume tubes in ICUs3:15  | Study design and challenges 6:19  | COVID-19 and adaptations to the study 8:46  | Limitations and interpretation of results11:23  | Next steps Soundtrack by The Underground Drive. All rights reserved. Listen more:https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmRNatasha Trehan (Producer), Giselle Joseph (Host), Emma Mahoney (Content Writer), Angela Guevara (Post-Production)

Batoul Jomaa from the University of Ottawa interviews Dr. Marisa Azad and Dr. Robin Patel on behalf of her team for the TMM4950 Science Communication course about improving the diagnostic methods for periprosthetic joint infections (PJIs). Dr. Azad is a senior scientist and physician of infectious diseases at the Ottawa Hospital Research Institute and a cross-appointed assistant professor at the University of Ottawa. Dr. Azad's research focuses on exploring PJI to develop more efficient diagnostic methods. Dr. Robin Patel is a director of the Infectious Disease Research Laboratory and a clinician at the Mayo Clinic. In this episode, Dr. Azad and Dr. Patel present their findings from their research on new diagnostic methods for PJI, how diagnostic methods can improve, and important considerations regarding PJI. Learn more: https://www.uottawa.ca/faculty-medicine/dr-marisa-azad0:05 | Introduction to podcast1:15 | Introduction to Dr. Azad1:44 | Why is diagnosing PJIs so difficult and what are the current standard treatments?4:20 | What is the BioFire Joint Infection (JI) panel and how does it work?5:20 | What are the plans to improve the accuracy of the BioFire Joint Infection (JI) panel?7:23 | How will antimicrobial resistance affect the prevalence of PJIs and diagnostic strategies?9:25 | Introduction to Dr. Robin Patel10:00 | Are PJIs typically caused by one or multiple microbes?11:58 | Will biomaterials reduce the risk of PJIs or introduce new problems?14:32 | Closing remarksCredits for music: Soundtracks by the Underground Drive. All rights reserved. Listen more https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmRBatoul Jomaa (Voice), Tony Lin (Post-Production), Abha Ranjitkar (Content Generation), Sam Khanlou (Producer)

In this episode, your host, Emily Schraeder, speaks to Dr. Christian Vaillancourt, Full Professor with the Department of Emergency Medicine, University of Ottawa, and Senior Scientist at the Ottawa Hospital Research Institute. His research looks at pre-hospital care, specifically improving care and survival for cardiac arrest and trauma victims. He implemented a multi-phase protocol to allow nurses to use automated external defibrillators (AEDs) during in-hospital cardiac arrest and studied its impact on survival. His research has a major impact on the care and treatment of cardiac arrest victims in our hospitals. We also hear from Julie Considine, Deakin Distinguished Professor, who is Chair of Nursing at Eastern Health and Director of the Centre for Quality and Patient Safety Research, who gives her point of view on this protocol.Learn more: https://www.ohri.ca/profile/cvaillancourt1:23 | What is an AED? Why is an AED important? 3:16 | Why is the 3-minute time frame so important? Why can it take up to 12 minutes for the first shock to occur?5:28  | Why are nurses not allowed to use AED in hospitals?7:47  | What were the study's challenges or different opinions and views?10:08  | From a nursing perspective, what are some strengths and weaknesses of this protocol?12:07  | How do you expect these protocols to be implemented in the long term?13:49  | Is there anything that you, Dr. Vaillancourt, want the listeners to know about AED use?Soundtrack by The Underground Drive. All rights reserved. Listen more:https://music.apple.com/ca/artist/the-underground-drive/1571062779 https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR                         Producer: Stephanie KhouryShow host: Emily SchraederWriter editor: Hannah Verge and Elizabeth ThibeaultAudio master: Stephanie Khoury and Emily Schraeder

Hosein Hosseini Abardeh, from the University of Ottawa, interviews Dr. Kusum Menon, a senior scientist at the CHEO Research Institute, to explore her research into pediatric septic shock. In this episode, we dive into critical topics such as the use of corticosteroids in managing pediatric septic shock and the challenges and benefits of using a deferred consent model for patient recruitment in clinical studies. Special guest Katie O'Hearn joins to provide additional insights into the complexities of conducting research in pediatric critical care.Learn more: https://www.cheoresearch.ca/research/find-a-researcher/kusum-menon/0:06 | Host introduction.0:27 | Introduction to Dr. Menon and Katie O'Hearn1:15 | Walking through Dr.Menon's scientific journey2:41 | Katie O'Hearn's role in the lab3:44 | Why are corticosteroids used for pediatric septic shock?5:28 | Challenges faced during the double-blind septic shock pilot study.6:14 | How were the challenges with steroid usage addressed for the study?7:52 | What is deferred consent? Why is it necessary? And how it was employed in the study.10:13 | Walkthrough of what happens when a child dies during the study.13:00 | Closing RemarksThis podcast features the song "Chroma Dusk" from Top-Flow on PixaBay, which is available under a Creative Commons Zero (CC0) license. Sergio Prosvirini created it.https://pixabay.com/music/beats-chroma-dusk-269465/Hosein Hosseini Abardeh (Host), Aaron Reyes (Producer), Malcolm Wilson (Audio), Vincent Baron (Script Writer)

As part of the BEaTS Research Radio Translational and Molecular Medicine Sci-Comm Podcast series, our host, Daniel Anderson, interviews Dr. Ruel and NP Ponnambalam. In this episode, Daniel, Dr. Ruel, and Ms. Ponnambalam discuss the promise of minimally invasive coronary bypass grafting (MICS CABG) and how it is a less invasive and safer option for patients who require coronary bypass surgery. Dr. Marc Ruel (MD, MPH) is the endowed chair of minimally invasive cardiac research at the University of Ottawa Heart Institute. He is also a Professor in the Division of Cardiac Surgery at the University of Ottawa Heart Institute. He is a Professor in the Department of Surgery and Department of Cellular and Molecular Medicine at the University of Ottawa. Menaka Ponnambalam (RN-EC, MN, NP-Adult) is a nurse practitioner in the Division of Cardiac Surgery at the University of Ottawa Heart Institute. Learn moreDr. Marc Ruel: https://www.ottawaheart.ca/profile/ruel-marcMenaka Ponnabalam: https://www.ottawaheart.ca/patients-and-visitors/clinical-departments/cardiac-surgery0:20 | Introduction to Dr. Marc Ruel & NP Menaka Ponnambalam1:22  | Origin of the MICS CABG Procedure4:39  | Patient Experience6:35  | Science Behind the Magic 8:20  | Future of Cardiac Surgery9:05  | Teamwork10:16  | Patient Advice13:29  | Conclusion & ResourcesMusic: Waltz in F# minor by Josh Zeldin & Huy K. Nguyen (unpublished composition). All rights reserved.Huy K. Nguyen (Producer), Daniel Anderson (Host), Josh Zeldin (Writer), Gil Toex (Editor) 

Tracy Xie, a student from the University of Ottawa, interviews Dr. Stephanie Willerth, a full professor and Tier II Canada Research Chair in Biomedical Engineering at the University of Victoria. In 2019, Dr. Willerth's group pioneered a new way to 3D print neural tissues using fibrinogen, a natural substance that helps our blood clot.In addition, Dr. Willerth is the CEO and co-founder of Axolotl Biosciences, a women-led biotech company. They have created the world's first commercial neuro-ink by bringing her 3D bioprinting technology to the market with Axolotl Biosciences! In this episode, we discuss the journey behind creating this versatile bioink, the advancements it helped lead to, and the exciting future of 3D bioprinting. Learn more about Dr. Willerth's work here: https://www.engr.uvic.ca/~willerth/Learn more about Axolotl Biosciences here: https://www.axolotlbiosciences.com/                 0:05 | BEaTS Research Radio and host introduction0:26 | Background on 3D bioprinting0:51 | Introduction to Dr. Willerth and her 2019 paper2:03 | Current landscape of 3D bioprinting3:17 | Key takeaways from Dr. Willerth's 2019 paper4:20 | What makes this bioink so special?4:53 | Choosing the right materials to support stem cell growth6:03 | Checking stem cell viability and differentiation into neurons6:54 | The biggest challenge in developing this protocol7:40 | Dr. Willerth's favorite parts of the project8:29 | Advancements and applications using this bioink!9:38 | Next steps from the Willerth Lab11:22 | Outro, and thank you for listening!Music by the Underground Drive. All rights reserved. Listen more:https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmRRyan Chan (Producer), Tracy Xie (Show Host), Abigail Shaver (Writer Editor), and Mia Petrović (Audio Master).

Larissa Yakoub from the University of Ottawa speaks with Dr. Betty Li, a researcher at the Human Health Therapeutics Research Center and an adjunct professor in the Department of Systems and Computer Engineering at Carleton University. In this episode, Dr. Li shares her recent findings in the development of 3D-printed materials for their application in vascular research and the creation of disease models.Access to Dr. Betty Li and her team's publication in Elsevier: https://doi.org/10.1016/j.bprint.2023.e00258Learn more about Dr. Li: https://carleton.ca/sce/people/li-2/ 0:03 | Introduction 1:23 | What motivated Dr. Li to advance bioprinting technology?4:47 | Who can benefit from 3D bioprinted blood vessels? 6:40 | Innovation of AGC bioink- How Dr. Li created a special type of ink (bioink) that can mimic real living tissue to be used in 3D bioprinting8:50 | 3D bioprinted vascular networks in drug discovery- How using 3D bioprinted blood vessels can help test new medicines10:24 | AGC bioink and ECM remodeling- AGC bioink reshapes the framework that supports your cells12:48| Dr. Li's expectations for her research15:12 | Conclusion and credits Soundtrack by penguinmusic. All rights reserved. https://pixabay.com/music/beats-lazy-day-stylish-futuristic-chill-239287/  Podcast by Larissa Yakoub (host, writer, and audio director) and Nada Abu Khater (producer, audio director, post-production, and writer). Social media collaboration by Suad Zain Aldeen and Darah Freije.

Omar Moghrabi from the University of Ottawa interviews Dr. Marceline Côté about using Sphingosine Kinase (SK) Inhibitors to treat enveloped viruses like Ebola. Dr. Côté is an associate professor at the University of Ottawa and the director of the Centre for Infection, Immunity, & Inflammation, where her research and practice involve antiviral treatments. In this episode, Dr. Côté weighs in on the emerging research that suggests that the use of SK inhibitors may be the future of broad-spectrum antiviral treatments. Omar and Dr. Côté discuss the mechanism, breadth, and safety of SK inhibitors in detail and the future of this post-entry approach to viral combat. Learn more: https://www.uottawa.ca/faculty-medicine/dr-marceline-cote0:03 | Introduction to the speaker1:04 | Lay Summary/intro to the topic1:54 | How do viruses like Ebola enter cells in the first place?4:50 | What are sphingosine kinases, and why are they such a good target for blocking viruses?6:00 | How effective is this approach across these viruses, and were there any surprises or interesting findings?8:48 | The future of broad-spectrum antiviral treatments and the potential of SK inhibitors10:22 | Known side effects of using SK inhibitors and safety concerns11:54 | Impact of SK Inhibitor Therapies on Public Health Responses During Viral Outbreaks13:16 | Outro and ThanksIntro: Sunny Brazilian Bossa Nova Jazz Podcast - Denis-Pavlov-Music;Outro: Context Sensitive - CHIPTUNEhttps://www.youtube.com/ContextSensitivehttps://contextsensitive.bandcamp.com/Producer: Zaid TaweelEditor: Zaid TaweelScript Writers and Editors: Aws Almir Ahmad and Paul Al HaddadShow Host: Omar Moghrabi

In this episode, Ali Abdalbari from the University of Ottawa's Translational and Molecular Medicine (TMM) program speaks with Dr. Morgan Fullerton, Professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa. This episode features a discussion surrounding Dr. Fullerton's most recent paper, published in the Atherosclerosis Journal (https://doi.org/10.1016/j.atherosclerosis.2024.117608). Dr. Fullerton provides an in-depth overview of his team's discoveries and offers his expertise in the field of metabolic research, highlighting the importance of model systems of disease and the implications of his research in this field.Learn more: https://doi.org/10.1016/j.atherosclerosis.2024.117608 Fullerton Lab: https://www.fullertonlab.com/0:10 | BEaTS and host introduction0:39 | Introduction to Dr. Fullerton1:39 | Podcast topic introduction1:56 | Guest welcome2:08 | Introduction to atherosclerosis3:44 | Focus of the Fullerton lab: metabolism and AMPK6:32 | Interlude: a study from collaborator Dr. Kim Loh7:04 | Concept of “negative data”7:43 | Data and challenges10:16 | Impact of research on the field of atherosclerosis11:33 | Accessibility and efficient communication in science13:23 | Podcast OutroSoundtrack by the Underground Drive. All rights reserved. Listen more:https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmRPodcast credits: Ali Abdalbari (Show Host), Brianna Kore (Audio Master), Michelle Levesque (Writer Editor), Peter Noel (Producer).

Matteus McCulloch from the University of Ottawa interviews Dr. Michele Ardolino, a senior scientist in cancer research at the Ottawa Hospital Research Institute and an Assistant Professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa. In this episode, Dr. Ardolino discusses a recent paper published by his lab about PD-L1 and its inhibition of the Type I IFN pathway during oncolytic virus infection, how the research came about, and the relevance of the work to advance cancer treatment.  Learn more about Dr. Ardolino and the work of the Ardolino Lab: https://www.uottawa.ca/faculty-medicine/dr-michele-ardolino https://ardolinolab.ca/0:00 | Introduction to PD-L1 and the type I IFN pathway and its relevance to recent research by Hodgins, J.J. et al. 1:40 | BEaTS, host, and guest introduction2:18 | What inspired the Ardolino Lab's exploration of PD-L1 and the type I IFN pathway?5:01 | What setbacks were encountered over the course of this study?6:35 | What is the mechanism of action for PD-L1 antibodies and oncolytic viruses in cancer therapy?8:17 | Clinical applications of PD-L1 antibodies and oncolytic viruses for cancer therapy9:50 | Impactful moments during the research process10:57 | Next steps in PD-L1 research12:02 | Advice for students entering research13:30 | End creditsThis podcast features the following songs: "Hidden Realm" by I.V.Lab, available under a Creative Commons Attribution-NonCommercial license.Listen here: https://archive.org/details/ffs62"600 light years" by Macroform, available under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 license.Listen here: https://archive.org/details/Macroform2011Matteus McCulloch (Podcast Host), Serena Bezanson (Script Writer), Sara Ladha (Audio post-production), Mattheuren Aucoin (Producer).

Anastasia Fahlman and Sarah Damiani from the University of Ottawa speak with Dr. Erin Mulvihill, Scientist and Director of the Energy Substrate Metabolism Research Laboratory at the University of Ottawa Heart Institute. Tune in to learn more about her recent work published in CellPress, which explores the potential mechanisms underlying the cardioprotective benefits of metabolic surgery and GLP-1RA-based therapies. It also discusses recent evidence and emerging therapies in this dynamic area of research. Learn more: https://www.sciencedirect.com/science/article/pii/S1043276024001930                                                                     Credits for music: Soundtracks by the Underground Drive. All rights reserved. Listen more: https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmRPodcast by Sarah Damiani (Voice, Producer, Show Co-Host, Writer Editor, Audio Master) and Anastasia Fahlman (Voice, Show Co-Host, Writer Editor, Audio Master)

Maryam Yassin from the University of Ottawa interviews Dr. Anna Jezierski and Dr. Alex MacKenzie. Dr. Jezierski is a research officer at the Department of Translational Biosciences in the Human Health Therapeutics Research Center at the National Research Council of Canada. She is also an adjunct professor for the Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa. In this episode, Dr. Jezierski shares her research on modeling the human blood-brain barrier using induced pluripotent stem cells and the various applications of this model in studying therapeutics for diseases of the central nervous system. We're also joined by Dr. Alex Mackenzie, an attending pediatrician and senior scientist at the Children's Hospital of Eastern Ontario (CHEO). He has served as the CEO and Scientific Director of CHEO Research Institute and is a cross-appointed member of the Faculty of Medicine at the University of Ottawa. Dr. Mackenzie comments on how this model is revolutionizing drug development. Learn more:  https://www.uottawa.ca/faculty-medicine/dr-anna-jezierski https://www.cheoresearch.ca/research/find-a-researcher/alex-mackenzie/0.03 | BEaTS and host introduction.0.26 | Introduction to Dr. Jezierski.1.17 | Introduction to Blood-Brain Barrier (BBB).3.22 | Creating a BBB model using induced pluripotent stem cells is important.7.07 | How tight junctions are replicated effectively.9.20 | Applications of the iPSC-derived BBB model.12.35 | Introduction to Dr. Alex Mackenzie12.51 | Implications of the model on drug discovery and clinical trials.14.54 | Closing remarks.Soundtracks by the Underground Drive. All rights reserved. Listen more https://www.dropbox.com/scl/fo/yrgjajtxzy4j08zj5iptc/AF7HMueoQwogLQMFxHxSHpU?e=1&preview=BEaTS+-+music+only+2.wav&rlkey=epcpj63eohwgi44mnqg7ctoa6&st=bn1v69ik&dl=0Maryam Yassin (Voice), Aysha Aftab (Post-Production), Dalia Zeidan (Content Generation), Jordan Yin (Producer). 

Join Kahliana Nguyen and Khaled Najjar, Translational and Molecular Medicine students, as they speak with Dr. Baptiste Lacoste, a neuroscience researcher at the Ottawa Hospital Research Institute whose recent work focuses on the critical role of the brain's vascular system in development.  The episode explores a new perspective on autism spectrum disorders (ASD) and how problems with the brain's blood vessels in early development may contribute to challenges seen in autism. Dr. Lacoste goes into depth on how these blood vessels play a role in brain growth, energy use, and behavior. By studying these interactions alongside neural and genetic factors, his research opens new avenues in how we understand autism and find better ways to address ASD. Whether you're a researcher, student, or simply curious, this episode offers an exciting new lens to the field. Learn more: Dr Baptiste Lacoste Dr Baptiste Lacoste | Faculté de médecine https://bsky.app/profile/blacoste.bsky.socialhttps://www.ohri.ca/profile/lacostelab0:02 | BEaTS and host introduction.0:22 | Introduction to Dr. Lacoste1:10 | Why did Dr. Lacoste choose to focus on the vascular system specifically?3:05 | The Neurovascular unit (NVU) and its importance in Dr. Lacoste's research on ASD5:15 | The use of mice with a 16p11.2 deletion mutation to study ASD8:43 | The novel findings were seen in Dr. Lactoste's lab study on ASD10:51 | Treatment Strategies when it comes to ASD12:03 | Limitations & Challenges Dr. Lacoste's lab faced and still faces while studying ASD13:50 | Wrapping up the episodeScience and Innovation by Vicate. All rights reserved. Listen more:https://www.jamendo.com/album/578641/science-and-innovationVicate | Jamendo Music | Free music downloadsKahliana Nguyen (Voice) & Khaled Najjar (Producer & Editor)

Lia Morton from the University of Ottawa interviews Dr. Marisa Azad. Dr. Azad is a physician-scientist at the Ottawa Hospital Research Institute and an Assistant Professor of medicine in the division of infectious diseases at the University of Ottawa. In this episode, Dr. Azad shares her insight and expertise on implant-associated infections (IAIs), notably the challenges of detecting and diagnosing IAIs and emerging diagnostic methods.Learn more: https://www.ohri.ca/newsroom/story/view/1543?l=en   0:00 | BEaTS and host introduction.0:38 | Introduction to Implant-Associated Infections (IAIs)1:40 | Introduction to Dr.Azad.2:11 | Why is IAI diagnosis so difficult, and what makes it particularly challenging?3:39 | Implant types that are notably hard to detect.4:29 | How do biofilms contribute to the formation of IAIs, and what makes them dangerous?7:41 | Limitations associated with microbiological analyses.11:09 |Future work and new approaches considered to identify IAIs.12:59 |The diagnostic methods currently being used in the clinic14:26 | Farewells and closure.Soundtrack by The Underground Drive. Song Titled: BEaTS. All rights reserved.https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmRLia Morton (Show Host, Content Generation), Julianne Morin (Production, Content Generation),  Amal Assebbane (Script, Content Generation), Adjia Seynabou Sy Gueye (Post-Production, Content Generation)

Maheen Khanotia from the Translational Molecular Medicine program interviews Dr. Barabara Vanderhyden, a distinguished researcher at the Ottawa Hospital and a professor at the University of Ottawa. She is a leading researcher in ovarian cancer, focusing on the BRCA1 and BRCA2 mutations. In this podcast, Maheen discusses with Dr. Vanderhyden her key findings in her 2023 paper "BRCA1 and BRCA2 deficient tumor models generate distinct ovarian tumor microenvironments and differential responses to therapy," where they delve into the world of cancer, Dr. Vanderhyden's lab findings, potential treatments, and research advice.Learn more:  https://www.ohri.ca/profile/vanderhydenlab/profile0:05 | BEaTS and host introduction.1:17 | Introduction to Dr. Barbara Vanderhyden.1:39 | How did you come to study ovarian cancer?2:48 | What led you to believe the BRCA1 and BRCA2 mutations are different?3:50 | What is the tumor microenvironment? 4:57 |  What do the research findings mean to the general public?6:05 | Why do BRCA1 and BRCA2 deletions at the gene and protein levels have different effects on tumor microenvironments? 8:04 | What were the challenges you went through as a researcher?9:18  | What were the crucial limitations of your research?10:24  | What are the future steps for ovarian cancer research?11:56  | What is general advice you would give to other researchers?12:55  | How long does a study like this take?13:40  | How does this research affect a patient's diagnosis?14:31  | Closing remarks Credits for music: Soundtracks by the Underground Drive. All rights reserved. Listen more https://music.apple.com/ca/artist/the-underground-drive/1571062779 https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmRMaheen Khanotia (Voice, host, editor), Soniya Agarwal (Producer, writer)

In this episode, Celina Tanbari from the University of Ottawa interviews Dr. Adam Rudner about the fascinating world of bacteriophages—viruses that target and kill bacteria. Dr. Rudner is the coordinator of the University of Ottawa's Phage Hunters program, a member of the SEA-PHAGES and SEA-GENES programs, and an Associate Professor in the Department of Biochemistry, Microbiology, and Immunology. Dr. Rudner shares with us his expert opinion on a study that isolated bacteriophages from human skin to kill infection-causing bacteria. The discussion delves into the therapeutic potential of phages, their involvement in biofilms and lysogeny, and the challenges associated with utilizing phages in medicine. This episode was produced and written by Emma Etchells Foisy, hosted by Celina Tanbari, and audio edited by Sam Rogers. Copyrights are reserved to BEaTS Research Radio and the University of Ottawa.If you are interested in learning more about the paper we discussed today, you can find it through the following link: https://pmc.ncbi.nlm.nih.gov/articles/PMC10117716/Learn more: https://www.uottawa.ca/faculty-medicine/dr-adam-rudner 0:03 | BEaTS and host introduction.0:38 | Introducing Dr. Rudner.1:05 | What are bacteriophages?1:41 | Phages as a possible solution to antibiotic-resistant bacteria 2:41 | What are biofilms, and how do they affect bacterial infections?5:01 | Phage BE01 and how lysogeny can affect phage therapy.8:52 | Phage BE04 and the potential of phages in replacing antibiotics. 10:55 | Squashing the stigma, phages only attack bacteria.12:35 | Potential challenges with phage therapy. 14:08 | Dr. Rudner's take-home message. 14:36 | Thank yous and credits!Soundtrack, Chillout by AudioCoffee | https://www.audiocoffee.net/Music promoted by https://www.chosic.com/free-music/all/Creative Commons CC BY-SA 3.0https://creativecommons.org/licenses/by-sa/3.0/

A series of interviews with presenters and participants at the Music and Health Research Institute's annual conference at The Royal Ottawa Mental Health Centre. This episode serves as an introduction to the ongoing work of institute members in the field of Music and Health research and practice.  Lucas Marchand (Interviewer, Post-production, Content generation, Producer)Learn more: https://www.uottawa.ca/research-innovation/music-health 0:02 | Host introduction.0:29 | Interview with Dr. Jane Gosine of Memorial University 2:15 | Interveiw with Ludovic Dubé4:34 | Interview with Dr. Chi Lo of Singwell9:45 | Interview with Dr. Erin Parks of Lotus Centre14:15 | Interview with Cory Butler of Zamar MusicOriginal music written and recorded by Lucas Marchand 

Deyanira Hernandez de la Universidad de Ottawa, habla con la Dra. Daniela Gordillo Bastidas, Directora Nacional del programa de Nutrición y Bienestar Integral del Tecnológico de Monterrey. En este episodio se abordan temas relacionados con medicamentos en el tratamiento de diabetes y diminución de peso, así como posibles efectos secundarios y criterios de evaluación para su prescripción.Acerca del Tecnológico de Monterrey: https://tec.mx/en1:39 -  El medicamento Ozempic originalmente se desarrolló como un medicamento para la diabetes tipo 2, sin embargo, ha ganado mucha popularidad en los últimos años, especialmente por su uso en la pérdida de peso. ¿Podría explicarle a nuestra audiencia cómo es que este tipo de medicamentos actúan en nuestro cuerpo?5:45 - ¿Qué consideraciones debería de tener en cuenta el personal de salud antes de prescribir este medicamento y cuáles podrían ser efectos secundarios de su uso?10:38 - En su experiencia, ¿cómo considera que se puede integrar a medicamentos como lo es ozempic en el tratamiento de pacientes que cumplan con los requisitos de su prescripción? ¿Es la medicación un sustituto o un complemento en el manejo del peso?

A series of interviews with presenters and participants at the Music and Health Research Institute's annual conference at The Royal Ottawa Mental Health Centre. This episode serves as an introduction to the ongoing work of institute members in the field of Music and Health research and practice.  Lucas Marchand (Interviewer, Post-production, Content generation, Producer)Learn more: https://www.uottawa.ca/research-innovation/music-health0:02 | host introduction.0:45 | Interview with Kayla Carter of Xenia Concerts https://xeniaconcerts.com/ 4:37 | Interview with Carlotte Gagnon of Opéra de Montréal's Opera Impact Program https://www.operademontreal.com/en/outreach-and-education 7:26 | Interview with Dr. Carol Wiebe of Radical Connections https://www.radicalconnections.ca/ 10:39 | Interview with Nicola Oddy https://nicolaoddy.com/ 14:02 | Interview with Diane Kolin of Arts Ably https://www.artsably.com/ Original music written and recorded by Lucas Marchand 

Nicole Chu from the University of Ottawa speaks with Dr. Javed Butler. Dr. Javed Butler, MD, MPH, MBA, is the President of the Baylor Scott and White Research Institute, and Senior Vice President and Maxwell A. and Gayle H. Clampitt Endowed Chair at the Baylor Scott and White Health in Dallas, Texas. He is also the Distinguished Professor of Medicine at the University of Mississippi in Jackson, Mississippi. In this episode, Dr. Butler shares with us the major findings from the recent EMPACT-MI clinical trial and his perspective on the future of heart failure therapies. The EMPACT-MI trial investigated whether a medicine called empagliflozin, a SGLT2 inhibitor, helps to lower the risk of heart failure and death in people had experienced a heart attack (myocardial infarction). Learn more about the EMPACT-MI clinical trial https://www.nejm.org/doi/full/10.1056/NEJMoa2206286 

Nicole Chu from the University of Ottawa speaks with Dr. Rosalin Miles. Dr. Miles is an active community member of the Lytton First Nation and a Research Associate in the Indigenous Health and Physical Activity program at The University of British Columbia School of Kinesiology. Her research focuses on the promotion of Indigenous health and wellness and understanding the value of traditional, cultural, and historical knowledge using a strength-based approach. Dr. Miles founded the Indigenous Physical Activity and Cultural Circle (IPACC), a national non-profit for First Nations, Métis and Inuit people who are involved in Traditional Activities, Fitness, Recreation, and Sports.Tune in to this episode to learn more about how the IPACC creates a community to promote physical activity as a way to health and wellness. Register for the upcoming National Indigenous Physical Activity & Wellness Conference Date: May 15th & 16th, 2024www.iactive.ca/conference/  Learn more: www.iactive.ca

Ryan Tu speaks with Dr. Emmanuel Stamatakis, a professor of physical activity, lifestyle, and population health at the University of Sydney, and a NHMRC Leadership 2 Fellow. Dr. Stamatakis focuses on cohort study-based research to correlate physical exercise to health. In this episode, Dr. Stamatakis explains his role in the Prospective Physical Activity, Sitting and Sleep consortium (ProPASS), how this helped him lead the development of activity guidelines for the World Health Organization, and how exercise is incorporated to the daily routine. Learn more: https://www.sydney.edu.au/medicine-health/about/our-people/academic-staff/emmanuel-stamatakis.htmlEpisode produced by Nicole Chu and hosted by Ryan Tu.

Jinane El-Hage from the University of Ottawa interviews Dr. Martin Gibala from the University of McMaster. Dr. Gibala is a professor of kinesiology, and his research focuses on the beneficial effects of exercise at the molecular to whole body level in both healthy individuals and those with chronic diseases. Dr. Gibala and his team are renowned for their work on high-intensity interval training and its impact on health, performance, metabolism, and even cognitive function. Dr. Gibala's expertise has led to the publication of "The One Minute Workout: Science Shows a Way to Get Fit That's Smarter, faster, and Shorter," a book that offers science-backed exercises and workouts for individuals seeking to achieve their health and fitness goals. Have you sought science-backed exercises and workouts that suit your lifestyle and health goals? Look no further as Dr. Gibala dives deep into what makes a healthy, practical, and uncomplicated exercise lifestyle. Learn more: https://martingibala.com/ 

Deyanira Hernandez from the University of Ottawa interviews Dr. Catherine Sabiston, an exercise and health psychology professor at the University of Toronto. Dr. Sabiston holds a Canada Research Chair in physical activity and mental health to conduct research on understanding physical activity, motivation, and mental health, including body image, physical self-perceptions, anxiety, depression, and stress. In this episode, Dr. Sabiston talks about her motivation to pursue a career in physical activity and mental health, the differences between multi-sport vs. single-sport approaches, and finally, she gives some advice for the community about how to create a more inclusive and appropriate environment where adolescents do not develop body-related shame and guilt. Learn more: https://kpe.utoronto.ca/faculty/sabiston-catherine

Armita Kalani from the Translational and Molecular Medicine (TMM) program at the University of Ottawa interviews Dr. Shawn Beug on behalf of her team for the TMM4950 Science Communication course. Dr. Shawn Beug is a Scientist at the CHEO Research Institute and an Assistant Professor at the University of Ottawa. Dr. Beug's research group focuses on understanding the factors involved in apoptosis (programmed cell death) and aims to develop new immune-based therapies for the treatment of cancer. In his quest to defeat cancer, Dr. Beug shares with us his research on a new class of drugs known as 'SMAC mimetics' as well as major findings from his 2017 Nature paper on the use of SMAC mimetics for glioblastoma treatment, and the results from ongoing clinical trials.To learn more, please visit: https://med.uottawa.ca/bmi/en/people/beug-shawn Episode credits: Ana Spasojevic (Producer), Armita Kalani (Host), Nicole Chu (Content Writer), Kirsten Chua (Video Editor)

Areej Khanotia, a student in the Translational and Molecular Medicine program at the University of Ottawa interviews Dr. Patrick Fafard. Dr. Fafard is a full professor and also serves in leadership roles for the Global Strategy Lab at York University and the University of Ottawa, the Centre for Health Law, Policy and Ethics, the Institute for Science, Society and Policy, and the Ottawa Hub for Harm Reduction. In this episode, Dr. Fafard shares his insight on the illusions and implications of the ‘just following the science' rhetoric in COVID-19 messaging. We explore whether policy makers are actually "following the science" or hiding behind experts to dodge the blame.Learn more: https://www.globalstrategylab.org/people/patrick-fafard/0:08 | BEaTS and Host Introduction 0:55 | Introducing Dr. Patrick Fafard!1:30 | Overview of study being discussed 4:45 | Negative concequences for leaders that rely on "the science"7:45 | Positive concequences for leaders that "follow the science"10:04 | Recommendations for leaders facing future healthcare crisis 11:52 | Future research plans extending from this work13:55 | Connecting with Dr. FafardPodcast by Areej Khanotia (Show Host), Hiba Alami Chentoufi (Audio Master), Hoda Osman (Writer Editor), Madeeha Shaikh (Producer)Music by the Underground Drive. All rights reserved. Listen more https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Megan Verma from the University of Ottawa interviews Dr. Ian Colman for the TMM4950 Science Communication podcast assignment. Dr. Colman is a professor in the School of Epidemiology and Public Health at the University of Ottawa, and he directs the Applied Psychiatric Epidemiology Across the Life-course (APEAL) Lab. In this episode, Megan explores Dr. Colman's research on how prenatal maternal stress negatively impacts children's behaviour and mental health after birth. In the conversation, they highlight the impact of parenting on children — positively noting how effective parenting can mitigate adverse behaviours. Learn more: https://med.uottawa.ca/epidemiology/people/colman-ian 0:06 | Podcast opening segment and introduction by host Megan Verma0:24 | Introduction to Dr. Ian Colman, his research, and the fetal programming hypothesis3:15 | Objectives of Dr. Colman's paper on prenatal maternal stress, children's mental health, and parenting6:32 | Impacts of prenatal maternal stress on children8:18 | Environmental factors contributing to mental health or behavioural problems in early childhood9:29 | Parenting behaviours that reduce the impact of prenatal maternal stress on children's mental health11:06 | Sex specific effects of parenting methods12:02 | Decreasing stress levels for pregnant people on a wider scalePodcast by Megan Verma (Host), Nassima Marouf (Producer), Ayesha Syed (Writer), Jenny Zhang (Audio Editor).This podcast features a song "Vibe Out" by Ellis Breen, available under a Creative Commons Attribution-NonCommercial license. Listen more:https://archive.org/details/EMC23001An_Hour_Of_EMCradio/015_Vibeout-Ellis_Breen.mp3

In this episode, Dr. Luca Pellegrini is interviewed by Olivia Hillier, with narration by Andrew Cao, from the University of Ottawa. Dr. Pellegrini is a new professor in the department of Biochemistry, Microbiology, and Immunology and is an expert on mitochondria and  inter-organelle contacts. He joins us to discuss his team's most recent paper, published in Cell Reports (https://doi.org/10.1016/j.celrep.2021.108873). This publication describes his team's discovery of the “wrappER”, a microscopic superhero in your body that plays a vital role in keeping you in top shape. Dr. Pellegrini takes us through the history of inter-organelle contacts research, the intriguing results detailed in his paper, and the broader implications of his findings to human health.  Learn more: https://www.pellegrinilab.com/ 0:27 | Podcast team introduction0:42 | Meet the wrappER, the cloak that safeguards your metabolic health.2:02 | Meet Dr. Luca Pellegrini, the founder of the wrappER.3:00 | How did Dr. Pellegrini come to study the wrappER?3:46 | Why does Dr. Pellegrini like history so much?4:41 | When did researchers start to consider how contacts between organelles may be important?5:58 | Diseases related to defects in inter-organelle contacts.6:48 | What you need to know about  Anastasia et al., 2021: the paper that discovered and defined the wrappER.8:12 | The wrappeR's structure is like a burrito.8:43 | Are all mitochondria wrapped by the wrappER?9:01 | The wrappER is not limited to liver cells.9:38 | What else can the wrappER wrap?10:12 | Dynamics of the wrappER and mitochondria.11:32 | How long did it take to make these discoveries of the wrappER?11:44 | The team behind the discovery.12:40 | What the wrappER can teach us about how our bodies regulate fat.13:18 | The wrappER and treatments for fat-related diseases and disorders.13:55 | Dr. Pellegrini's plans as a new profressor and principal investigator at the University of Ottawa.14:22 | Wrapping up: thank you to Dr. PellegriniPodcast by Andrew Cao (Narrator and Post-Production), Olivia Hillier (Interviewer), Olivia Sommers (Producer), & Anna Wang (Writer-Editor).Music:“The Launch” by Chronox (https://freemusicarchive.org/music/Chronox_2/)  This song can be found on the Free Music Archive (https://freemusicarchive.org/music/Chronox/Voyager/Chronox_-_01_-_The_Launch/)“Nocturnal (BGM)” by LEMMiNO (https://www.lemmi.no/)  “Thannoid” by Blue Dot Sessions (https://www.sessions.blue/)   “Are We Loose Yet” by Blue Dot Sessions (https://www.sessions.blue/)   “Here” by Hyson (https://iamhyson.bandcamp.com/)   

In the latest episode of 'Neural Networks,' your Neural Networks host Lillian Abebe, a passionate advocate for neuroscience and neurophilosophy, engages in a thought-provoking conversation with Dr. Georg Northoff. As a distinguished philosopher, neuroscientist, and psychiatrist leading the Mind, Brain, and Neuroethics Research Unit at the Royal Institute of Mental Health Research, Dr. Northoff shares profound insights into the intersection of philosophy, neuroscience, and psychiatry.Explore the intricacies of distinguishing between the brain and the mind, unravel the conceptual illusions of consciousness, and dive into the development of biomarkers for conditions like Complete Locked-In Syndrome (CLIS). Join Lillian and Dr. Northoff as they discuss the challenges of defining consciousness in scientific terms and the latest breakthroughs in understanding the connections between the brain and the mind.Learn more: www.georgnorthoff.com 3:33 | Distuinguishing brain from mind5:32 | Areas of development in elucidating brain-mind connections.7:08 |  Techniques used to measure consciousness12:15 | The importance of making science accessiblePodcast by Abby Cherinet (producer), Lillian Abebe (host), Selam Yimer (writer), Xeius Tran-Wong (editor)Soundtrack by Blue Fox Music through Renderforesthttps://bluefoxmusic.com/

This episode of Beats Radio, hosted by Danyaal Ansari, written by Shay Patel, produced by Hasssan Taleb, and edited by Anas Khoja, features an in-depth discussion with immunology expert Dr. Michele Ardolino from the University of Ottawa and the Ottawa Hospital Research Institute. The conversation centers around the fascinating interplay between the immune system and cancer, with a particular focus on the process of trogocytosis and its role in immune evasion by cancer cells. Dr. Ardolino elaborates on his groundbreaking research into how cancer cells transfer PD-1 to Natural Killer (NK) cells via trogocytosis, effectively inhibiting these critical components of the immune response. This detailed exploration sheds light on the sophisticated mechanisms cancer cells employ to evade immune detection and opens up discussions about potential therapeutic strategies targeting these interactions.https://www.ohri.ca/profile/mardolino/cancer-immunology-lab0:00 - Introduction0:57 - Trogocytosis Explained2:51 - Choosing Trogocytosis for PD-1 Transfer Study5:00 - NK Cells' Functional Variability8:10 - Immune System's Complexity & Beauty10:50 - Rapid Fire Q&A14:27 - Closing RemarksPodcast by Danyaal Ansari (Host), Shay Patel (Writer), Hasssan Taleb (Producer), Anas Khoja (Editor)Music by "Podcast Background Music"  https://www.youtube.com/watch?v=cdFqvdekuvI 

Alzheimer's is a disease unique in the lack of treatment dand diagnostic techniques aimed at mitigating it's effects.  To address these issues, researchers at Dr. Clifford Cassidy's neuroscience lab are investigating the use of novel imaging techniques that have great potential to improve both our understanding of molecular mechanisms underlying Alzheimer's and improve our ability to predict the development of it's symptoms. At the heart of these new techniques is a brain structure called the locus coeruleus (LC), which is the primary site of release of a chemical called norepinephrine. It has already been established that gradual degeneration of the LC is an important feature of alzheimer's disease. However, the contribution of this degeneration to development of disease symptoms remains poorly understood due to limitations in existing imaging techniques. To solve this issue, Dr. Casidy's lab is investigating the use of Neuromelanin, a pigment found abundantly in the LC to more accurately detect this structure's degeneration and its relation to Alzheimer's and its symptoms.Learn more: https://www.cliffordcassidy.com/00:00 I Podcast Introduction02:32 I Overview of the Cassidy Lab4:24 I What is NM-MRI?6:40 I Overview of the Paper about NM-MRI9:40 I What is the role of neuroadronergic system in psychotic symptom progression?12:20 I What is the broader role of NM-MRI14:30 I OutroPodcast by Patrick Chary(Host), Abdul Karim Halal (Producer), Elijah Van Dinther (Script), Nicholas Lafreniere (Editor).Soundtrack by the Underground Drive, Song title: Nobody. All rights reserved.Listen more: https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Amy Stewart from the University of Ottawa speaks with Dr. Marta Cerruti, a professor in the Department of Mining and Materials Engineering at McGill University, a prominent figure in the research field of bio-synthetic materials, and the team leader of the Bio-Interface lab. As of today, Dr. Cerruti is the co-director of the McGill Institute for Advanced Materials and an associate member of the Faculty of Dentistry and the Department of Bioengineering. In the Bio Interface lab, her work centers around the incorporation of implants, tissues and drugs into the human body, as well as how minerals such as calcium and magnesium are formed in living organisms that help her address the questions of curing mineral-based diseases. Today, we'll be discussing her work centering around mineral deposits that lead to aortic valve stenosis.Learn more: https://www.mcgill.ca/materials/marta-cerruti0:15 l Introduction to BEaTS and Dr. Cerruti1:25 l What is aortic valve calcification and what are the causes?2:54 l Are there other minerals that develop in the heart?3:45 l What are the methods used to view clacium deposits?7:06 l Differences in calcification between men and women12:01 l Future research14:10 l Conclusion14:45 l CreditsPodcast by Amy Stewart (Show Host), Shikshita Singh (Producer), Minh Tran (Writer Editor), Jade Gamelin Kao (Audio Master).Soundtrack by Lexin_music featuring the song "sicence documentary". All rights reserved. Listen more: https://pixabay.com/music/build-up-scenes-science-documentary-169621/

Fiona Haugen of the University of Ottawa speaks with Dr. Smita Pakhale of the Ottawa Hospital Research Institute about the impact of health inequities on the development of obstructive lung diseases in urban poor populations. Dr. Pakhale is a Senior Scientist, staff respirologist at The Ottawa Hospital, and associate professor at the University of Ottawa who created The Bridge Engagement Center. The Bridge conducts research in partnership with and to improve the well-being of underserved populations in Ottawa, Ontario. Learn more: https://bridgeengagement.ca/00:05 | Introduction01:10 | Overview of Dr. Pakhale's research02:51 | The Bridge Engagement Center03:44 | Tobacco and Ottawa's urban poor population05:51 | Social determinants of health and lung disease07:18 | Building trust with marginalized communities09:15 | Unjustified exclusion of underserved communities in mainstream research 11:22 | Addressing inequities in health and research13:01 | How can we do our part?14:12 | Conclusion and thanksPodcast by Fiona Haugen (host and graphic design), Amandine Courtemanche (writer), Mairead Green (producer), Jade Poirier (audio-producer and writer)Soundtrack by Grand_Project from Pixabay. All rights reserved. Listen more: https://pixabay.com/users/grand_project-19033897/?utm_source=link-attribution&utm_medium=referral&utm_campaign=music&utm_content=177572 https://pixabay.com//?utm_source=link-attribution&utm_medium=referral&utm_campaign=music&utm_content=177572 

Nandini Biyani from the Translational and Molecular Medicine program at the University of Ottawa interviews Dr. Leila Mostaço-Guidolin, an assistant professor at Carleton University in the Department of Systems and Computer Engineering. With a focus in 3D-bioprinting, Dr. Mostaço-Guidolin leads a tissue engineering and bioimaging lab. In today's podcast, Dr. Mostaço-Guidolin dives into her research regarding the use of a microfluidic-based 3D bioprinting technology to synthesize new vasculature.            Learn more: https://carleton.ca/mostacoguidolin/0:28 | Topic Introduction 0:36 | Guest introduction 1:25 | Interest in the field of 3D bioprinting?3:23 | Elaborating on the study 4:51 | Specific choice of SV-ARBEC cells 8:31 | What is microfluidic-based 3D bioprinting? 9:56 | Limitations of the study 12:56 | Future steps 14:00 | Catch you later!   This podcast was produced by Nandini Biyani (the show host), Esha Gahunia (the writer editor) & Gurrose Gahla (the audio master).                                        Soundtrack by The Underground Drive. All rights reserved. Listen more:https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Siyona Kassel, a Translational and Molecular Medicine student at the University of Ottawa, interviews Dr. Juan Valerio Cauich-Rodriguez. Dr. Cauich-Rodriguez is a researcher at the Centro de Investigación Científica de Yucatán in Mexico, possessing a Bachelor of Science in Industrial Chemistry, a Masters in Polymer Science & Technology, and a PhD in Biomedical Materials. He is currently engaged in the development and assessment of new materials for their role in Regenerative Medicine, with a specific focus on the use of synthesized polymers. In this episode, Dr. Cauich-Rodriguez discusses his research using a unique and innovative polymer blend to advance the field of vascular grafts for medical application.Learn more: https://www.cicy.mx/unidad-de-materiales/investigador/juan-valerio-cauich-rodriguez0:21 I Introduction: Cardiovascular grafts0:49 I  Intro to Dr. Juan Valerio Cauich-Rodriguez1:29  I Dr. Cauich-Rodriguez's science background and current research3:08  I  Polymers for biomedical applications in Mexico4:21  I  What are polyurethanes?6:39  I  Biomaterials as a treatment for cardiovascular disease 8:40  I  Designing synthetic vascular grafts with polymer blends10:40  I  Staying on top of the latest advancements in the field of regenerative materials12:05  I  Personalized medicine and biomaterials 13:29  I  Dr. Cauich-Rodriguez's future directionsPodcast by Siyona Kassel (Voice), Caleb Lakhani (Content Generation), Paul Nguyen (Producer and Post-Production) Credits for music: Soundtrack provided by the Underground Drive all rights reserved. Listen more: https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Zachary Mitchell from the University of Ottawa speaks with Angelico Obille, a PhD candidate at the University of Toronto Institute of Biomedical Engineering in the Biological & Bioinspired Materials Laboratory. Tune in to learn more about their research on proteins involved in freshwater mussel adhesion and how this can be applied to develop new medical adhesive technology.Learn more: https://www.sonelab.bme.utoronto.ca/00:04 I Intro01:05  I Why is it important to study freshwater mussel adhesion?02:15  I What is a byssal proteome and what does it show us?04:16  I What's special about the proteins of zebra mussels that allows them to stick so well to wet surfaces?07:38  I Can you explain why you don't fully agree with considering these mussels as an invasive species?11:52  I How have these mussels impacted our ecosystem?13:24  I What do you think about biocontrol and do you think there is a way to live harmoniously with these animals?14:15  I OutroPodcast by Liliana Austin, Safa Ghaziasgar, Samarth Chauhan, and Zachary MitchellSoundtracks by the Underground Drive. All rights reserved. Listen more:https://music.apple.com/ca/artist/the-underground-drive/1571062779  https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR   

Devin Brain from the University of Ottawa interviews Dr. May Griffith. Dr. May Griffith is a lead researcher at Université de Montreal and holds a Canada Research Chair in Biomaterials and Stem Cell Ophthalmology. She is one of the brilliant minds behind the development of LiQD Cornea, an injectable liquid that gels in the eye to help heal corneal perforations. In this episode, Dr. Griffith shares the story that inspired her to study eye conditions and shares her incredible research focused on developing a gel for corneal regeneration.Learn more: https://www.griffithresearch.ca/may-griffith-20:07 | BEaTS and host introduction0:37 | Statistical introduction to the cornea1:01 | Introduction to Dr. May Griffith1:40 | Dr. Griffith's story of inspiration3:30 | What is a corneal perforation and how are they aquired?4:25 | Addressing problems with current treatments for corneal perforations using LiQD Cornea6:07 | LiQD Cornea administration route in relation to accessibility8:00 | Future plans for LiQD Cornea treatment 9:15 | What should patients expect from this treatment, short and long-term?10:46 | Closing remarks and creditsErica Anderson (script writing), Devin Brain (host), Rosalie Salati (audio editor), Tamara Synek (script writing).  All shared role of producerSoundtrack by The Underground Drive. All rights reserved. Listen more:https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Anabella Nakhle from the University of Ottawa interviews Dr. Stephanie Willerth. Dr. Stephanie Willerth is the CEO of Axolotl Biosciences, a 3D bioprinting company  in Victoria, BC. She is also a a Canada research chair and full professor of Biomedical Engineering at the University of Victoria, and an Adjunct Professor at the University of Missouri. In this episode, Dr. Willerth shares about her research in developing a 3D bioprinted Alzheimers disease model that replicated the native tissue environment. Learn more: https://www.engr.uvic.ca/~willerth/ https://www.axolotlbiosciences.com/ Anabella Nakhle (Voice), Serena Solari, Elie Njeime, and Mathania Vuningoma (Post-production, graphic designer and producer)0:06| BeaTs and host introduction. 0:29 | Topic introduction. 0:59| Introduction to Dr. Willerth1:47| Introduction to 3D bioprinting and bioink that was used for the disease model2:43|Why was alzheimer's used as the disease model in this paper?3:55 |Differences in modeling  parkinson's disease vs alzheimer's disease.4:30| Cell viability in the bioink5:20| markers for cell death6:00 | The future and challenges of 3D bioprinting in disease model development7:14| Ethical issues that are faced with using patient-derived tissue8:55| Ensuring the genotype of the induced pluripotent stem cells (iPSCs)10:20| membrane potential of the bioprinted cells11:10| Future involvement in the bioprinting field for listenersSoundtrack by Funky Giraffe. All rights reserved. Listen more: https://open.spotify.com/track/1ZOKcgiydsTA6OVdkraVN5https://artlist.io/royalty-free-music/song/are-you-ready-for-me-baby/63852  

Meron Samuel Demissie from the University of Ottawa speaks with Dr. Jean-François Couture, Full Professor and Chair in the Department of Biochemistry, Microbiology and Immunology in the Faculty of Medicine at the University of Ottawa. Tune in to learn more about their studies on structural biology and epigenetics to understand the importance of small molecules and proteins' functions for the treatments of different conditions such as cancer.Learn more: http://jfclab.ca/0:15  |  Introduction and Description1:27  |  X-Ray Crystallography2:55  | Epigenetic Processes5:15  | Role of X-Ray Crystallography in protein-protein interaction, precisely histones10:13 | Closing Remarks and Advice for traineesCredits for music: Soundtracks by the Underground Drive. All rights reserved. Listen more https://music.apple.com/ca/artist/the-underground-drive/1571062779 https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR 

Félix Labonté, an undergraduate student in the Translational and Molecular Medecine program at the University of Ottawa speaks with Dr. Dylan Burger. Dr. Burger is an associate professor at The University of Ottawa in The Department of Cellular and Molecular Medicine, cross-appointed member in the School of Pharmaceutical Sciences, and an investigator at The Ottawa Hospital Research Institute. Tune into today's podcast to learn more about Dr. Burger's research, published in the Journal of Extracellular Vesicles which demonstrates how extracellular vesicles secreted by the kidneys could potentially be used for targeted therapy advancing our knowledge on diabetic nephropathy and treatments. Learn more: https://www.ohri.ca/profile/dylanburger 0:16  | Introduction1:00  | Dr. Dylan Burger Introduction1:44  | What are extracellular vesicles and what role do they play in healthy cells?2:52  | What is diabetic nephropathy and why is your lab interested in this condition?3:55  | What is the impact of diabetic kidney disease on microparticles released by the podocytes?4:35  | What is the impact of the microparticles released by the podoocytes?5:57  | What would be the next steps for your lab to complete to understand the mechanism of intracellular communication between the podocytes and the proximal tubule epithelial cells?7:16  | Are there any specific medications being tested right now as potential treatments for these types of kidney diseases?8:26  | For extracellular vesicles in general, what's their potential to be used as biomarkers for certain diseases? How could it be used in a clinical setting?10:24  | Closing remarks10:48  | ConclusionSoundtracks by the Underground Drive. All rights reserved. Listen more: https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Hannah Deyell from the University of Ottawa interviews Dr. Adam Rudner on his current research and experience. Dr. Adam Rudner is an Associate Professor at the University of Ottawa in the Department of  Biochemistry, Microbiology and Immunology, a member of the SEA-PHAGES and SEA-GENES programs, and the coordiantor of uOttawa Phage Hunters. The primary research focuses of Dr. Rudner's team are exploring the potential applications for baceteriophage therapy, building essential research skills, and exploring bacteriophages with interesting genomic sequences. In this episode, Dr. Rudner explores how bacteriophages can target antibiotic resistance for patients with disseminated bacterial infections, how his lab is working to increase the pool of available phages, and how personalized medicine can be used to improve patient outcomes with phage therapy. Learn more: https://rudnerlab.med.uottawa.ca/Adam_Rudner_Lab/Home.html00:00  | Introduction01:00  |  Dr. Adam Rudner's recent research focuses and ongoing projects 02:13  |  The roles of bacteriophages and how they function to treat bacterial infections03:04  |  Advantages of bacteriophage therapy over tradtional antibiotics in the context of antibiotic resistance 04:13  |  Challenges associated with research related to bacteriophages / limitations of bacteriophage therapy 05:44  |  Primary motivators for using engineered bacteriophages as a treatment for 15-year old cystic fibrosis patient07:51  |  The purpose of engineering bacteriophages to effectively treat the patient10:23  |  The undergraduate SEA-PHAGES Program 11:48  |  Dr. Adam Rudner's research advice to undergraduate students 13:17  |  ConclusionCredits for music: Soundtracks by the Underground Drive. All rights reserved. Listen morehttps://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Rama El Hakim from the University of Ottawa speaks with Dr. Doug Coyle, Professor at the University of Ottawa in the School of Epidemiology and Public Health. Listen in to learn about Dr. Coyle's recent work in CJC Open, which determines that lifesaving drug Canakinumab needs a cost reduction of 91% to be feasible in Canada. Learn more: https://med.uottawa.ca/epidemiology/people/coyle-doug00:10  |  Introduction01:41  |  Dr. Coyle's Current Research Focuses 03:37  |  Applications to Other Healthcare Systems 08:14  |  Is the suggested 91% price reduction of Canakinumab feasible? 10:05  |  Translating this research to clinical settings 11:05  |  Advice to the general public 14:52   | Wrap-Up Soundtrack by Secret Ops. All rights reserved. Learn more: https://cctrax.com/mystified/secret-opshttps://creativecommons.org/licenses/by/4.0/

In this special episode, Dr. Gabriela Ghisi talks about the educational component and its impact on cardiac rehabilitation, the challenges of cardiac rehabilitation programs across the globe, and the advancements of the International Council of Cardiovascular Prevention and Rehabilitation. Learn more: https://kite-uhn.com/scientist/gabriela---melo-ghisi

Spinal Muscular Atrophy (SMA) is a devastating genetic disease that causes muscle weakness and atrophy (shrinking of muscles) in children. There is currently no cure for this disease; however, base editing, a type of gene therapy, provides potential. Dr. Rasthmi Kothary is the Deputy Scientific Director and Senior Scientist at the Ottawa Hospital Research Institute. His lab focuses on understanding the mechanisms that underlie muscle and nervous system integrity. In this episode, Dr. Kothary gives us a greater insight on what SMA is, how it is currently being treated, and his research so far on a new base editing system to potentially cure this disease. Episode produced & hosted by: Nicole Chu Learn more: https://www.ohri.ca/profile/rkothary

 Jinane E. from the University of Ottawa interviews Dr. Mete Civelek, a distinguished researcher and professor in the department of biomedical engineering at the University of Virginia. Dr. Civelek's research focuses on studying the complex interactions between genes and the environment that increase the risk of heart disease and type 2 diabetes. Dr. Civelek and his team employ cutting-edge bioinformatics tools to unravel the molecular pathways associated with these diseases and to develop personalized medicine strategies for cardiovascular and metabolic disorders. If you've ever been curious about computational biology applied to gene expressions, this episode is a unique opportunity to gain insights. Dr. Civelek provides an in-depth exploration of his research in systems genetics aimed at understanding cardiometabolic diseases.Learn more: https://civeleklab.org/

Nicole Chu from the University of Ottawa speaks with Sarah Groom, a Life Sciences recruitment professional and leader of the Pharmaceutical & Life Sciences recruitment division at Groom & Associates. Sarah holds Bachelor's and Masters degrees in medical chemistry from the University of Ottawa. In this episode, Sarah gives us an introduction of GROOM, Canada's leading recruitment firm, and shares some advice for recruitment. Learn more: https://www.groomassocies.com/about/