This podcast is about Intensive care pharmacology and physiology. This is created to prepare intensive care trainees for their primary CICM exams. However, it will be of benefit to anyone who works in intensive care and keen to acquire new knowledge or want to refresh their memory.
In this episode, we discuss the concept of Work of breathing and lung efficiency.
In this episode, we discuss the procedural anatomy of the femoral vein including surface
In this episode, we discuss the process of fibrinolysis in relation to coagulation cascade and the pharmacology of Alteplase.
In this episdoe, we compare and contrast fentanyl and remifentanyl.
in this episode, we discuss the role of various receptors and describe the terms - partial agonist, antagonist, and inverse agonists.
In this episode, we discuss the concept of venous admixture and the effect of supplemental oxygen on it in adults.
In this episode, we discuss the consequences of sudden and sustained afterload increase on the Left ventricle.
In this episode, we discuss the differences between two diuretic medications - Furosemide and Acetazolamide.
In this episode, we discuss various opioid receptors, their characteristics, distribution and activation process.
In this episode, we discuss various mechanisms by which the kidney concentrates urine.
In this episode, we discuss the CVS changes after the birth.
In this episode, Dr Mike Clifford talks about respiratory changes occurring at birth.
In this episode, we discuss the key characteristics of uteroplacental circulation, including double Bohr and double Haldane effect.
In this episode, Mike and I discuss the physiological changes in the cardiovascular system during pregnancy and at the term, their implication on pharmacokinetics.
In this episode, Mike and I discuss the respiratory changes during the pregnancy and at the term.
In this episode, we discuss the control of breathing and its clinical relevance.
In this episode, Mike discusses arterial pressure transducers, including natural frequency, resonance and damping.
In this podcast, we discuss CO2 carriage in blood.
In this episode, we discuss the structure and functions of adult haemoglobin.
In this episode, we discuss various pharmacokinetic and pharmacodynamic changes that take place at term during pregnancy.
In this snippet, we cover all the physiological factors affecting Cardiac output.
In this episode, we discuss various physiological factors affecting airway resistance.
In this episode, Dr Mike Clifford explains the physiology of West Zones.
in this episode, we discuss the pharmacology of GTN.
In this episode, Mike talks about the principles of Hemofiltration and hemodialysis, along with the composition of fluid used in dialysis.
In this episode, Dr Mike Clifford explains the pathways for corneal, pupillary light, oculomotor and gag reflexes.
In this podcast, Maddi and I discuss the factors affecting SVR.
In this episode, Maddi covers various factors affecting PaCO2 levels.
In this episode, we discus briefly the physics of ultrasound, the Doppler effect and the properties of transducers.
In this episode, we discuss the classification of anti-psychotic medications and haloperidol pharmacology in depth.
In this episode, we discuss various mechanisms for body water regulation.
In this episode, we discuss the concept of mixed venous oxygen saturation and various factors affecting it.
In this episode, we discuss the pharmacology of 4% albumin.
In this epsiode, we discuss the MOA and adverse effects of iNO and prostacyclins.
In this epsiode, I discuss the events following vessel injury leading up to clot formation.
In this episode, I discuss the physiology of smooth muscle cell contraction and how it differs from skeletal muscle cell contraction.
In this episode, I discuss the importance and limitations of Serum creatinine and creatinine clearance for renal function assessment.
Wish you all a very happy 2023. From this episode, we will bring you the new series called Primary snippets, covering all difficult questions with less than a 50 % pass rate. The first snippet covers the impact of critical illness on pharmacokinetics.
Join us in this episode, where we discuss the pharmacology of IV albumin, PRBC, along with the process of blood grouping and cross-matching.
Join us as we discuss the pharmacology and pharmacokinetics of blood thinning agents commonly used in the Intensive Care setting. Test yourself on our fun fact questions and more.
In this episode, we discuss the functions of the liver, hepatic blood flow and the role of the cytochrome system in drug metabolism in intensive care.
In this episode, we discuss the physiology of neuromuscular junction, the pharmacology and the principles of neuromuscular monitoring.
In this episode, we discuss coagulation cascade, the principles behind ROTEM and the pharmacology of Tranexamic acid.
In this episode, we discuss the physiology and pharmacology relevant to an elderly patient admitted to the intensive care unit.
In this episode, we discuss 1. How does thermoregulation work in Santa? 2. How does a thermometer work? 3. What are the physiological effects when Santa returns to the North Pole?
In this episode, we continue to discuss how to prepare for primary exams at the bedside. We discuss carbohydrate metabolism, the pharmacology of TPN and the measurement of basal metabolic rate.
In this episode, we discuss the pharmacology of oxygen, the physics behind oxygen sensors in the ventilator and the mechanism of oxygen delivery.
In this episode, we discuss the anatomy of brainstem reflexes along with the pharmacology of mannitol, phenytoin and levetiracetam.
In this episode, we discuss the modified Pomodoro technique for bedside Primary exam preparation. We examine the neurointensive care patient to discuss the anatomy of CSF production, Cerebral blood flow regulation and physics of ICP monitoring.
In this episode, we discuss the modified Pomodoro technique to help Primary candidates prepare for their exams during daily bedside ward rounds. 3 questions were discussed in this episode - Pulse oximeter, Comparison between Noradrenaline and vasopressin, and physiological effects of hypoxia.