Podcasts about Cerebral

CORE RESOURCES: Rutherford's Vascular and Endovascular Therapy 10th Edition, Chapters 88, 89, 91, and 94 Atlas of Vascular Surgery and Endovascular Therapy 2nd Edition, Chapter 9 ADDITIONAL RESOURCES: Audible Bleeding Episodes Holding Pressure - Carotid Endarterectomy: https://www.audiblebleeding.com/2024/02/27/holding-pressure-carotid-endarterectomy/ Holding Pressure Case Prep - Endovascular Basics: https://www.audiblebleeding.com/2023/04/23/holding-pressure-case-prep-endovascular-basics/ Videos TCAR Technical Video: https://jnis.bmj.com/content/14/8/842 Articles Society for Vascular Surgery clinical practice guidelines for management of extracranial cerebrovascular disease:  https://www.jvascsurg.org/article/S0741-5214%2821%2900893-4/fulltext Technical aspects of transcarotid artery revascularization using the ENROUTE transcarotid neuroprotection and stent system: https://www.jvascsurg.org/action/showPdf?pii=S0741-5214%2816%2931862-6 Referenced Studies ROADSTER-1 https://pubmed.ncbi.nlm.nih.gov/30611582/ ROADSTER-2 https://pubmed.ncbi.nlm.nih.gov/32811386/ https://pubmed.ncbi.nlm.nih.gov/35381327/ TCAR Surveillance Project https://jamanetwork.com/journals/jama/fullarticle/2757579?utm_source=openevidence&utm_medium=referral https://pubmed.ncbi.nlm.nih.gov/36172943/   OUTLINE:   CAROTID ARTERY DISEASE 1. Pathophysiology/etiology Carotid artery disease is primarily driven by atherosclerotic plaque deposition.  Risk factors: hypertension, hyperlipidemia, diabetes, smoking, and advanced age. Nonatherosclerotic etiologies: fibromuscular dysplasia, carotid dissection, vasculitic disease, carotid webs, and trauma. When the endothelium is damaged, monocytes migrate to the site and differentiate into macrophages that take up oxidized LDL particles to become foam cells. Meanwhile, an inflammatory response occurs where activated platelets release thromboxane A2, platelet derived growth factor, and inflammatory cytokines that promote further platelet aggregation and vascular inflammation. Smooth muscle cells migrate and proliferate, forming the structural framework of the atheroma.  Within the lesion, necrotic debris and lipid accumulate, creating a vulnerable plaque. Plaque rupture exposes this material to the bloodstream, serving as a nidus for thrombus formation which can lead to ischemic events. Carotid bifurcation is particularly prone to plaque formation due to turbulent blood flow. Embolization of plaque from this area can result in TIA or ischemic stroke.  2. Presentation Patients are often asymptomatic and stenosis is incidentally found on imaging.  Symptomatic patients present with neurologic symptoms including unilateral motor and sensory loss, aphasia (difficulty finding words), dysarthria (difficulty speaking), amaurosis fugax (temporary monocular vision loss due to embolus to the ophthalmic artery), transient ischemic attacks Physical exam findings may be notable for auscultation of a carotid bruit. Patients may also have evidence of retinal artery embolization on fundoscopic examination (Hollenhorst plaque) or asymptomatic cerebral infarction.  3. Diagnosis USPTF recommends against screening for asymptomatic carotid artery stenosis.  In patients with no risk factors, SVS recommends against screening for asymptomatic carotid artery stenosis. However, they do recommend screening for asymptomatic clinically significant carotid bifurcation in certain groups of patients with multiple risk factors.  These risk factors include patients with clinically significant peripheral vascular disease, patients 65 and older with history of CAD, smoking, hypercholesterolemia, and patients prior to coronary artery bypass.  Relevant findings on physical exam or imaging findings may warrant screening, but screening is not recommended for the presence of neck bruit alone without other risk factors, as this finding has a low sensitivity and specificity for detecting clinically significant carotid artery stenosis.  Carotid duplex ultrasound: first-line imaging modality for both screening and initial evaluation of stenosis, noninvasive, low-cost CTA: rapid, high-resolution, three-dimensional imaging of vascular anatomy, risk of contrast and radiation exposure MRA: high-quality, three-dimensional imaging without radiation or contrast, expensive with longer acquisition time, can overestimate stenosis in severe disease DSA/angiography: gold standard, expensive, invasive, not generally recommended for routine diagnostic evaluation or screening 4. Classification Carotid artery stenosis is classified by degree of luminal narrowing. NASCET method: standard in current practice. Compares the minimal residual lumen at the point of greatest stenosis to the diameter of the normal distal internal carotid artery.  Classification of stenosis: Mild: 70 bpm, and ACT >250 seconds to optimize cerebral perfusion and minimize thrombotic risk. Clamp the carotid artery just proximal to the arterial sheath to establish active flow reversal.  Flow controller settings: Low setting High setting Flow-stop button: allows for temporary cessation of flow (used when we inject contrast).  Confirm flow reversal via two different ways:  The first way is to stop flow to the venous return sheath with the stopcock, clearing the line with hep saline injection, and then opening the stopcock and seeing the blood returning to the controller in a reverse fashion. The second way is to perform an angiogram with a small amount of contrast injection while holding the flow-stop button. Using the angio we want to make sure that contrast is flowing retrograde in the cervical ICA thereby confirming flow reversal.    Carotid artery stenting, balloon angioplasty, and completion angiogram At this point, a standard carotid angioplasty and stenting procedure is performed. ENROUTE transcarotid Neuroprotection System device:  inner diameter of 8F and an outer diameter of 10F Has its own carotid artery stent system but is also compatible with all FDA-approved carotid stents.  Final angiogram is performed to confirm stent position, vessel patency, and absence of complications including vasospasm at the distal end of the stent and filling defects from protrusion of atheromatous material through the stent    Cessation of flow reversal and sheath removal Allow the flow reversal to run for a few minutes after the final balloon angioplasty to clear any debris.  Antegrade flow is restored by releasing the carotid clamp and closing the stopcocks on the neuroprotection system.  The patient is auto-transfused the blood from the flow line back to the venous system.  As the arterial access system is removed and the puncture site is closed with the U-stitch.  IV protamine is administered to reverse the heparin. Standard closure is performed at the incision site. Meanwhile, hemostasis is achieved after removal of the femoral vein sheath with brief manual compression.  Postop care/complications Postop care All patients after a TCAR should be monitored in the ICU setting for 24 hours, as an embolic stroke, hypotension with or without bradycardia, or hypertension can occur.  Should a TIA or stroke be observed, a carotid duplex scan and CT angiogram should be immediately obtained to assess the stent site and the presence of an embolic or thrombotic filling defect, dissection, or occlusion.  Dual antiplatelet therapy: continue for 45 days to 12 months Aspirin and statin therapy: continued indefinitely Surveillance duplex imaging: 4 weeks, 6 months, and 12 months, and annually thereafter. Postop complications Hematoma Stroke Myocardial infarction Cerebral hyperperfusion syndrome Sudden and excessive increase in cerebral blood flow to previously hypoperfused brain tissue is met with vasculature that cannot constrict appropriately from chronic vasodilation Leads to breakthrough hyperperfusion. This results in cerebral edema, intracerebral hemorrhage, and neurological symptoms.  Cranial nerve injury Hypoglossal nerve (CN XII) injury: ipsilateral tongue deviation. It is the most commonly injured cranial nerve.  Vagus nerve (CN X) injury: hoarseness and possible vocal cord paralysis.  Glossopharyngeal nerve (CN IX) injury: soft palate dysfunction.  Recurrent laryngeal nerve injury: voice hoarseness and inability to cough as it innervates all of the voice box muscles except for the cricothyroid muscle Marginal mandibular nerve injury: ipsilateral lip droop, injury is rare in TCAR.  Stent restenosis Pseudoaneurysm Access site infection

Cerebral interface is activated! And go for Giant Robot Hellboy Book Club! Join us as we sort through the listener feedbag, share some animated recommendations and get strapped to a chair contraption and made to control a giant bookclub member! Then follow along as we adore Duncan Fegredo's art in "Giant Robot Hellboy!" Fire Knuckle Grenades! 03:40 - Listener Feedback  13:06 - Whaddya See, Whaddya Say 25:38 - Giant Robot Hellboy Check out some Muffin But Good Vibes performances! https://open.spotify.com/playlist/6fFUsodW4iCtCe4CXkNCLp?si=nRxNpjX3RAS4bV8Xkq9aNg https://open.spotify.com/playlist/0c01A2HniCU6v4xZeFznCm?si=vGdbl4tpTHWUbxgJStvIhw https://www.youtube.com/watch?v=KHy1irHT2cI Check out Eric Askue on Instragram https://www.instagram.com/reels/DY-8UAAuCjj/ https://gkus.us/ Thank you Dr. Frinkelstein for sharing your 3D printed "Magician & The Snake!" https://www.printables.com/model/1728678-the-magician-and-the-snake-statue Follow the good Doctor, here https://bsky.app/profile/doctorfrinkelstein.bsky.social "Death Beyond Death: Jian Spirits in Chinese Popular Belief," by Elizaveta Volchkova https://www.researchgate.net/publication/371591669_Death_Beyond_Death_Jian_Spirits_in_Chinese_Popular_Belief opening & closing theme by https://onlybeast.com

Your weekly dose of information that keeps you up to date on the latest developments in the field of technology designed to assist people with disabilities and special needs. Special Guest: Jack Walters – CEO and Co-Founder – HapWare website: https://hapware.com Email: info@hapware.com PreOrder: hapware.com/preorder Learn more about Bridging Apps at www.bridgingapps.org —————————— If you […]

What does it mean to adapt, advocate, and build a life on your own terms while living with cerebral palsy?In this episode of The Cerebral Palsy Perspective Podcast, Chad Williams and Daryl Perry sit down with Gillian Jasper, a writer, advocate, public speaker, and storyteller who shares her experiences navigating life with cerebral palsy, epilepsy, and other challenges.Gillian discusses growing up with disabilities, learning to accept and adapt to the realities of cerebral palsy, the impact of seizures and mobility challenges, and how writing became an important outlet for sharing her story with the world. She also shares her passion for disability advocacy, creating awareness, and helping others better understand what it means to live with a disability.Throughout the conversation, Gillian opens up about overcoming self-doubt, finding confidence in her own voice, and why she refuses to let a diagnosis define who she is or what she can accomplish.Topics Covered:• Growing up with cerebral palsy and epilepsy• Being born premature and overcoming long odds• Physical therapy and adapting to daily challenges• Disability advocacy and awareness• Writing as a form of self-expression• Living with seizures and mobility limitations• Social media and finding community• Public speaking and storytelling• The importance of self-acceptance• Why disability does not define a personGuest Links:Gillian Jasper Instagram:https://www.instagram.com/gillianjasper_Cerebral Palsy Through My Lens:https://www.jewishnewhaven.org/press-releases/cerebral-palsy-through-my-lens-the-hand-i-have-been-dealtHost Links:Chad Williams:https://www.instagram.com/chadwillia1Daryl Perry:https://www.instagram.com/daryltperryThank you for listening to The Cerebral Palsy Perspective Podcast. If this conversation resonated with you, please share it with someone who could benefit from hearing Gillian's story and perspective.

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La doctora Carolina de Miguel Benadiba, coordinadora del Servicio de Rehabilitación —Unidad de Daño Cerebral, Unidad de Lesión Medular y Servicio de Rehabilitación Musculoesquelética— en Fundación Hospitalarias Madrid Hospital Beata María Ana nos cuenta, entre otros temas, qué perfiles reúnen los distintos profesionales que trabajan en estos procesos de rehabilitación y qué beneficios tiene este enfoque interdisciplinar para pacientes y familias, con objetivos tan importantes, además de la recuperación física, como la autonomía personal, la reintegración social o la vuelta a las actividades de la vida diaria. Además, tras haber presidido la Sociedad Española de Rehabilitación y Medicina Física y ocupar actualmente la vicepresidencia, nuestra especialista valora la evolución de la especialidad durante los últimos años y el papel cada vez más revelador en la rehabilitación de tecnologías como la IA o la robótica.

ResearchWorks is heading to AACPDM 2026 in Philadelphia this year!We can't wait to see you there - it's a special 80th Annual Meeting for the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM).Join with us as we speak with Dr Kristie Bjornson - live from EACD 2026 in Galway Ireland, the final episode that we recorded on our European tour! A preview of what to expect from this year's annual congress and a look at the host city, Philadelphia!Register here:https://www.aacpdm.org/events/2026/registration

Nos acompaña la doctora Carolina de Miguel Benadiba, coordinadora del Servicio de Rehabilitación —Unidad de Daño Cerebral, Unidad de Lesión Medular y Servicio de Rehabilitación Musculoesquelética— en Fundación Hospitalarias Madrid Hospital Beata María Ana. Con ella repasamos la visión integral e interdisciplinar de la rehabilitación en un centro donde hace ya más de un siglo las Hermanas Hospitalarias atendían a niñas con secuelas de poliomielitis y desarrollaban terapias de rehabilitación innovadoras para la época. Ahora, tal y como nos explica nuestra invitada, el hospital sigue ese legado y presenta recursos específicos y punteros como gimnasios especializados, salas de robótica, simuladores realidad virtual y espacios de terapia ocupacional, que combina siempre con una atención personalizada, en la que el factor humano, tanto para los pacientes como para las familias, se erige una de sus piedras angulares.

Your weekly dose of information that keeps you up to date on the latest developments in the field of technology designed to assist people with disabilities and special needs. Special Guest: Mark Larson – Owner and Founder – Marblesoft LLC Website: https://keyguardat.com/ Email: sales@marblesoft.com Phone: 763-755-1402 Stories: Apple Steady Hands Story: https://apple.co/4uIe6bf Learn more about […]

En la Historia Sonora de hoy con Ana Francisca Vega por MVS Noticias: Periodista independiente con parálisis cerebral logra entrevista exclusiva con Messi: “Me hiciste muy feliz”See omnystudio.com/listener for privacy information.

Join us as we discuss this week's stupidity in the world

En este episodio, converso con Carlos Henao sobre una experiencia que transformó profundamente su manera de ver la vida, el trabajo, el éxito y las prioridades.Carlos comparte su historia personal tras enfrentar un tumor cerebral, desde el impacto inicial del diagnóstico hasta el proceso de cirugía, recuperación y reeducación del cuerpo. También hablamos sobre resiliencia, familia, liderazgo, espiritualidad, humor en momentos difíciles y la forma en que una experiencia límite puede cambiar la relación con el futuro, la ambición y la muerte.Una conversación honesta sobre aceptar lo que no controlamos, encontrar perspectiva en medio de la incertidumbre y recordar qué es verdaderamente importante.Capítulos:00:00 Introducción a momentos transformadores01:37 La historia de Carlos: de Venezuela a Barcelona09:05 El camino hacia el marketing y la creatividad17:24 Decisiones de vida: cambios y oportunidades25:30 El impacto del tumor cerebral en la vida de Carlos28:47 La llegada de la familia y el apoyo emocional29:50 Reflexiones sobre la vida y la muerte31:16 La dificultad de compartir el proceso con los seres queridos32:48 La perspectiva espiritual y estoica de la experiencia35:08 Lecciones de vida y la aceptación de la mortalidad37:35 El impacto del pasado familiar en la experiencia actual40:05 La experiencia de la cirugía y el humor en momentos difíciles42:18 El proceso de recuperación y la reeducación del cuerpo44:57 El lado emocional y la descalibración tras la experiencia46:57 Cambios en la perspectiva y la planificación futura48:18 Compartiendo aprendizajes y el deseo de ayudar a otrosConecta:LinkedIn de Carlos: https://www.linkedin.com/in/chenao/ This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit becomingschool.substack.com

Running a brewery used to be a simple proposition: make great beer, open the doors and let the taps do the talking. But Anne Abrahamson says that model is outdated. As the director of operations at Cerebral Brewing, one of Denver's most recognizable breweries, Abrahamson helps oversee the business behind the beer. Since joining Cerebral in 2019, she's helped the company grow from one crowded taproom off Colfax to three locations across the Denver area, with a fourth on the way. On this episode of the Voices of Experience podcast, she shares what it takes to run a modern craft brewery, why hospitality has become central to the beer business, and why Cerebral is focused on evolution over expansion. Table of Contents • 1:21 Growing from one taproom to three • 3:18 Why Colorado craft beer is bucking the trend • 5:44 Balancing art, science and spreadsheets • 7:55 Leaning into non-alcoholic beer • 9:42 Making sustainability work for the business • 11:27 Falling into craft beer in Japan • 13:52 Solving problems behind the scenes • 14:49 Building culture across multiple locations • 19:11 Why breweries have to innovate • 19:48 Choosing evolution over expansion • 22:42 Show notes and credits

El experimento del médico especialista en melanoma para tratar su cáncer cerebral despertó la esperanza de un avance significativo.

Embora represente uma pequena fração dos tumores malignos — entre 1,4% e 4% segundo dados do Instituto Nacional de Câncer (INCA) —, a gravidade desta condição é desproporcional à sua incidência. A cada ano, surgem no Brasil cerca de 11 mil novos casos de tumores do sistema nervoso central, que incluem cérebro e medula espinhal. Entre crianças e adolescentes, o câncer cerebral é a segunda principal causa de morte por câncer, atrás apenas das leucemias. Sobre o assunto, o âncora Jota Batista conversa com o neurocirurgião João Gabriel Ribeiro Gomes, no Canal Saúde desta sexta-feira (5).

An evidence-based, standardized, and practical diagnostic framework for cerebral palsy.

Helping Children Flourish: Parent-Informed Social Narratives to Support Readiness for Upper Limb Rehabilitation in Cerebral Palsy

El Proyecto GR5 es un evento de creación propia, en el que pretendo recorrer los 220kms. y 10.000 de desnivel positivo de este recorrido, que se inica en Sitges y finaliza en Canet de Mar (ambas ciudades en la provincia de Barcelona).Lo haré en semiautosuficiencia (aprovechando poblaciones, supermercados, gasolineras y todo aquello que encuentre a mi paso) y en solitario. Sin pretensiones horarias ni competitivas.En este proyecto, probaré varios productos de la marca Rossignol, Bollé, Black Diamond, UYN y Overstims.Bienvenido/a a este podcast, en el que te cuento a pie de camino, mis andanzas probando material en situaciones reales.Contacto:juan@ellaboratoriodejuan.com

Your weekly dose of information that keeps you up to date on the latest developments in the field of technology designed to assist people with disabilities and special needs. Special Guest: Freek van Welsenis – CEO – Hable iamhable.com Learn more about Bridging Apps at www.bridgingapps.org Link to INDATA AT Awareness Day Open House Video: […]

Does multi- level surgery weaken muscles in ambulatory youth with CP?

Non-invasive Measurement of work of breathing in children and young adults with high level cerebral palsy.

Optimising the neuroplasticity window: from evidence to early CP intervention

Neurowashing in Early Intervention: A Review of Neuroscience Rhetoric and an Appraisal Tool.

Health-Related Quality of Life after Guided Growth Treatment for Hip Displacement in Young Children with Cerebral Palsy

Power mobility experience, meaning and outcomes for children with complex non-ambulant cerebral palsy: A scoping review

Enhancing Mobility in Students with Non-Ambulatory Cerebral Palsy in School Settings: A Scoping Review of the MOVE Program

Implementing low-cost powered mobility devices in children with Cerebral Palsy: from concept to clinical practice  (workshop)

Con más de 10 años en emisión, Canal del Misterio, dirigido y presentado por Nuria Mejías, es un espacio dedicado a explorar los grandes enigmas del universo, la conciencia y la espiritualidad, uniendo misterio, crecimiento personal y nueva conciencia en cada programa. En esta edición comenzamos con Cristina Cuesta y el emotivo caso de un gatito, una historia de sensibilidad, empatía y amor hacia los animales. Cristina Molina nos acerca a La Frontera del Conocimiento, explorando los límites entre ciencia, tecnología y conciencia, y planteando nuevas preguntas sobre la naturaleza de la realidad. Ricard Salom nos guía a través de una meditación dedicada a los cuatro elementos —tierra, agua, aire y fuego— para ayudarnos a encontrar equilibrio, conexión y armonía interior. En Recetario de Salud, Javier Akerman nos habla del antienvejecimiento cerebral y comparte claves para cuidar nuestra mente, potenciar la memoria y favorecer el bienestar cognitivo. Nuria Pérez nos lleva Al Otro Lado del Velo, compartiendo historias, señales y experiencias que invitan a reflexionar sobre la realidad espiritual y aquello que existe más allá de lo visible. Cerramos con Juan Perdomo y El Consejo de la Semana, una guía simbólica para afrontar los próximos días a través de cartas, runas y oráculos. Un programa para quienes desean comprender la vida, la conciencia y las realidades que existen más allá de lo visible. #CuatroElementos #AntienvejecimientoCerebral #Conciencia #Espiritualidad #Misterio #CanalDelMisterio #Meditacion

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(3:41) Coñecemos as novidades do concurso de relatos científicos InspiraCiencia con Ana Yeste (CSIC-Delegación de Cataluña). Achegámonos á xornada “Neurotecnoloxía para a medicina” no CHUAC, organizada polo grupo Neurocom da Universidade da Coruña. (10:12) Conversamos con Elena García Armada (Marsi Bionics/CSIC), pioneira no desenvolvemento do primeiro exoesqueleto robótico do mundo para nenos e nenas con enfermidades neurolóxicas. (38:35) Repasamos a primeira aplicación da penicilina no “Calendario da historia da ciencia” de Moncho Núñez. (40:25) Falamos tamén con Antonio Oliviero (Hospital Nacional de Parapléxicos de Toledo), presidente da Sociedade Española de Estimulación Cerebral, que explica como os campos magnéticos permanentes producidos por potentes imáns poden aliviar dores e mellorar síntomas neurolóxicos. A nosa web oficial www.efervesciencia.org

AbstractThis article explores the often-overlooked tragedy of promising happiness through overcoming disability. It draws on qualitative interviews and focus groups with 36 adults with cerebral palsy to explore how medical discourse shapes the ways in which individuals are encouraged to pursue a good life, leading to unintended consequences. Sara Ahmed's theory of happiness is used to understand the dialectics of pursuing a good life through overcoming disability, revealing how medical interventions and discourse during childhood inadvertently contribute to feelings of inferiority and social alienation. The article highlights the need to reconsider how individuals with disabilities are encouraged to pursue a good life, emphasizing the paradox of disabling effects arising from attempts to minimize and overcome disability.https://www.sciencedirect.com/science/article/pii/S027795362500098X

Your weekly dose of information that keeps you up to date on the latest developments in the field of technology designed to assist people with disabilities and special needs.   Special Guest: Mary Wilcox – Solutions Expert – Aventido https://sensoryreadable.com email mary.wilcox@adventino.com US Resellers: Boundless Technologies, Westminster Technologies and AT Discount —————————— If you have […]

La ex primera dama de Estados Unidos le dijo a CBS News que le asustó el desempeño de Joe Biden frente a Donald Trump.

Send us Fan MailCould putting a few drops of breast milk in a preterm infant's nose actually improve cerebral oxygenation? In this episode of Journal Club, Daphna reviews a randomized controlled trial from the European Journal of Pediatrics investigating the physiologic effects of intranasal expressed breast milk (EBM) administration in preterm infants. The study found that infants receiving 0.2 mL of fresh breast milk intranasally three times daily showed significantly higher cerebral oxygenation levels, along with more favorable trends in heart rate and respiratory rate, compared to controls. While time to full oral feeding and length of hospital stay were unchanged, the safety data is reassuring. Ben and Daphna discuss what outcomes we should even be measuring, and whether the evidence is already good enough to just do it.----Effect of intranasal breast milk administration on cerebral oxygenation, vital signs, and transition time to full oral feeding in preterm infants: a randomized controlled study. Yücel A, Küçükoğlu S, Konak M.Eur J Pediatr. 2026 Apr 16;185(5):272. doi: 10.1007/s00431-026-06922-6.PMID: 41986747Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

I am sitting here writing up this week's Outspoken Review in my knickers. I'm sweating in places that I didn't know could sweat and I'm frequently spritzing the poor, over-heated rabbit with water.Anyway, heat aside, I have some lovely products to tell you about this week including a brilliant SPF, the best tinted lip balm (that I've been using as a highlighter too), minty freshness from Neom, some mind-blowing fragrances and two simple but impressive recipes.Enjoy fellow Outspoken Beauties xx

Time toxicity and shared decision-making in cerebral palsyDavid B Frumberg, Paige T Church, Nathan RosenbergPMID: 41387091 DOI: 10.1111/dmcn.70123AbstractClinicians and families regularly enter into a process of shared decision-making. Seldom, if ever, however, is the critical question of time usage, or, more specifically, time-related burdens, accounted for when establishing goals and outcome measures. Time-related burdens are not included, for instance, as an outcome measure in cerebral palsy research-something which may have profound effects about which we are unaware. By contrast, in the field of oncology, time-related burdens, or, more technically, what has been termed time toxicity, has been increasingly studied. Building on that work, we seek to apply the concept of time toxicity to people with disabilities who interface with healthcare at great frequency.https://pubmed.ncbi.nlm.nih.gov/41387091/

Your weekly dose of information that keeps you up to date on the latest developments in the field of technology designed to assist people with disabilities and special needs.   Special Guest: Jason Ray – CEO – SimplyHome Website: https://simply-home.com —————————— If you have an AT question, leave us a voice mail at: 317-721-7124 or […]

In this inspiring interview, worship leader Trent Cokley shares his journey from gospel roots to leading worship in Washington D.C., the importance of authenticity in music, and how faith sustains him through life's challenges. Discover practical insights on leading with joy, embracing vulnerability, and the power of seeking God's presence in every aspect of life. Connect with Trent: Instagram: @trentcmusic +++++ Worshipology with Kurtis Parks is a part of the Worship Leader Magazine Podcast Network. WL Mag exists to equip Spirit-led worship leaders with practical tools, theological insight, and encouragement for the local church. This episode was brought to you by PraiseCharts. If you are a Worship leader or musician, when it comes to leading in church or playing worship music, you need reliable, high-quality music resources. Check out PraiseCharts.com today and see how it can transform your worship ministry!  ++++++++++ To learn more about Kurtis and his book Worshipology: www.worshipologybook.com or www.kurtisparks.com 

Creatine and Microbiomes A new 2026 Cell Metabolism study explores a compelling and increasingly central idea in modern biology: the gut/brain/immune/metabolism axis is not just associative, it is mechanistic. Specifically, Dr. Lu and colleagues investigate how the gut microbiota can directly influence depressive behavior by reshaping systemic and neural metabolism. This is another in a long running list of papers describing the amazing work that bacterial commensal microbes do for us. In this case, our minds and moods. "Although peripheral-brain crosstalk regulates energy metabolism, its role in depression remains unclear. Here, we used metabolic profiling to reveal elevated fecal creatine alongside reduced plasma and cerebrospinal fluid creatine in both patients with depression and mouse depression models. Exogenous creatine produced antidepressant-like effects mediated by gut microbiota. Bifidobacterium pseudolongum was identified as a significantly reduced gut bacterial species in depression, correlating with impaired creatine absorption. Subsequent supplementation with Bifidobacterium enhanced the antidepressant effects of creatine. Mechanistically, B. pseudolongum-derived acetate promoted the creatine transporter (Slc6a8) expression in intestinal epithelial cells via histone acetylation. The Slc6a8 mediated the antidepressant-like effects of creatine. Neuronal creatine deficiency influenced energetic metabolism and neurophysiological function. In patients with depression taking antidepressants, co-administration of creatine and Bifidobacterium increased plasma creatine levels and reduced depression scores. These findings identify the Bifidobacterium-creatine combination as a promising antidepressant strategy and highlight the critical role of gut-brain energy metabolism in depression." "The brain, as an energy-intensive organ, relies on precise metabolic regulation to maintain synaptic plasticity, neurotransmitter synthesis, and stress response systems. Accumulating evidence implicates energy metabolism dysregulation as a hallmark of depression. Neuroimaging studies using positron emission tomography (PET) have identified marked glucose hypometabolism in the medial prefrontal cortex (mPFC) of patients with depression. Cerebral mitochondrial dysfunction and ATP imbalance have been mechanistically linked to depression progression. Notably, emerging studies emphasize the bidirectional interplay between peripheral metabolic signals and central energy regulation, which is fundamental to neural metabolism. Clinical observations such as fatigue, appetite dysregulation, and unexplained weight fluctuations in patients with depression further suggest systemic metabolic disturbances spanning peripheral organs and the CNS.." (Lu et. al. 2026) This is next-level medicine. Mental health can no longer be framed as a disorder of genetics, experience, or circumstance alone. This work opens a clearer window, showing how the microbiome participates as an active partner, shaping brain function through the metabolites it helps produce and deliver. Compounds like creatine are no longer just peripheral players. They become signals, fuel, structure, and information, bridging gut and brain, metabolism and behavior.... and more Enjoy, Dr. M

From Childhood to Adulthood: Lifespan insights into health and health service needs in cerebral palsyKeynote session: Oceania Academy Of Cerebral Palsy And Other Childhood-onset Disabilities

Your weekly dose of information that keeps you up to date on the latest developments in the field of technology designed to assist people with disabilities and special needs.   Special Guest: Claudiu Hidas – CEO – Munevo Website: https://us.munevo.com Facebook: https://www.facebook.com/munevo.social Instagram: https://www.instagram.com/munevo_usa/ LinkedIn: https://www.linkedin.com/company/munevo/ Stories: Telecoil Story: https://bit.ly/4etQulG Learn more about Bridging Apps at www.bridgingapps.org Link to […]

In this week's episode, Blood editor Dr. Laurie Sehn interviews Drs. Reuben Kapur and Robert Campbell on their latest articles published in Blood. This episode highlights two groundbreaking studies exploring how inflammation drives serious blood and immune-related diseases. In the first interview, Dr. Kapur discusses how inflammatory bowel disease (IBD) can both promote and worsen clonal hematopoiesis of indeterminate potential (CHIP), with large-scale human data and mouse models identifying REF1 as a key mediator and potential therapeutic target. The second segment features Dr. Campbell, who explains how heme released during malaria infection activates platelet mTOR signaling, intensifying cerebral malaria and suggesting new avenues for platelet-targeted treatments. Together, the conversations reveal how inflammatory pathways and immune signaling contribute to disease progression while opening the door to novel precision therapies. 

Your weekly dose of information that keeps you up to date on the latest developments in the field of technology designed to assist people with disabilities and special needs. Special Guest: Dr. Jeannette Mahoney – Founder and President – Jet Enterprises Inc. https://www.catchu.net Email: jeannette@catchu.net Stories: University of Detroit Mercy Story: https://bit.ly/4cLZQXC Learn more about […]

Longitudinal decline in upper-limb range of motion in adults with cerebral palsyErika Cloodt, Jenny Hedberg-Graff, Anna Lindgren, Marianne Arner, Evgenia Manousaki, Katina Pettersson, Elisabet Rodby-BousquetAbstractAim: To analyse longitudinal changes in passive range of motion (ROM) in the upper limb in adults with cerebral palsy (CP).Method: Passive ROM for shoulder abduction and flexion, supination, and elbow and wrist extension was analysed in a longitudinal cohort of adults aged 16 to 76 years from the Swedish CP registry. Individual ROM trajectories and mean ROM curves were calculated using the Manual Ability Classification System (MACS). A mixed-effects model was used to examine changes over 3 to 13 years 7 months.Results: In total, 1395 adults with CP were analysed (769 males, 626 females; median age 26 years). A continuous decline in shoulder ROM, supination, and wrist extension was observed across all MACS levels. Decline rates differed between MACS levels for shoulder flexion, elbow extension, and wrist extension, with steeper declines at higher MACS levels (levels IV and V). Adults classified in lower MACS levels (I and II) had greater initial ROM and slower declines compared to adults classified in higher MACS levels.Interpretation: Upper-limb ROM continuously declined in adults with CP, particularly at higher MACS levels. The varied decline rates highlight the need for tailored interventions and systematic follow-up to maintain ROM and functional ability, especially among individuals at higher risk.

Your weekly dose of information that keeps you up to date on the latest developments in the field of technology designed to assist people with disabilities and special needs.   Special Guest: Mindy Brown , M.S. – Senior Director, Client Solutions – Louisiana Association For The Blind www.lablind.com Phone: 318-698-2300 x106 Email: mbrown@lablind.com Link to […]

Luis Herrero entrevista a Francesc Feliú, abogado del espacio jurídico Feliú Fins, que representa legalmente a una moderadora de contenido de Tik Tok.

Your weekly dose of information that keeps you up to date on the latest developments in the field of technology designed to assist people with disabilities and special needs. Special Guest: Mark Prohaska – District Manager – SafeInHome Suzanne Raymond – Remote Supports Consultant, Northwest Indiana – SafeInHome www.safeinhome.com Phone: 219-794-5345 email: sraymond@safeinhome.com —————————— If […]

An Auckland University researcher is using virtual reality, 3D printing, and real-time data to design and create leg braces for children with cerebral palsy, that are more comfortable. Cerebral palsy affects 1 in 500 New Zealand children, and 7000 New Zealanders currently live with cerebral palsy. It generally appears in very early childhood as the result of brain damage that occurs before or during a baby's birth, and the main symptoms are related to movement and posture. About half of children with cerebral palsy need ankle-foot braces to help them walk and prevent muscle tightening, but they can be bulky and uncomfortable. Sara Chami worked as a clinical orthotist in Tehran fitting braces for children. And also studied prosthetics. She's now with Auckland University's Bioengineering Institute and researching if the braces can be built better.

Elisa Saleme, especialista en medicina de Urgencias