The body's hormone-producing glands
Dr. Beverly Moy is back on the ASCO Guidelines Podcast to discuss the latest guideline rapid recommendation update regarding sacituzumab govitecan for patients with hormone receptor-positive HER2-negative metastatic breast cancer based on recent evidence published in TROPiCS-02. Dr. Moy reviews how this update intersects with the previous rapid recommendation update on trastuzumab deruxtecan and future areas of research that may impact further updates to this evidence-based guideline. Read the latest update, "Chemotherapy and Targeted Therapy for Endocrine-Pretreated or Hormone Receptor–Negative Metastatic Breast Cancer: ASCO Guideline Rapid Recommendation Update" at www.asco.org/breast-cancer-guidelines. TRANSCRIPT Brittany Harvey: Hello and welcome to the ASCO Guidelines podcast, one of ASCO's podcasts delivering timely information to keep you up to date on the latest changes, challenges, and advances in oncology. You can find all the shows, including this one at asco.org/podcasts. My name is Brittany Harvey and today I'm interviewing Dr. Beverly Moy from Massachusetts General Hospital in Boston, Massachusetts, lead author on ‘Chemotherapy and Targeted Therapy for Endocrine-Pretreated or Hormone Receptor–Negative Metastatic Breast Cancer: ASCO Guideline Rapid Recommendation Update'. Thank you for being here, Dr. Moy. Dr. Beverly Moy: Thank you for having me, Brittany. I'm glad to be here. Brittany Harvey: Then first, I'd like to note that ASCO takes great care in the development of its guidelines and ensuring that the ASCO conflict of interest policy is followed for each guideline. The full conflict of interest information for this guideline panel is available in line with the publication of the guideline in the Journal of Clinical Oncology. Dr. Moy, do you have any relevant disclosures that are directly related to this guideline topic? Dr. Beverly Moy: I do not have any relevant disclosures. Brittany Harvey: It's great to have you back on the podcast. Last we spoke, we were discussing the July 2022 rapid update of this guideline regarding the use of trastuzumab deruxtecan. What prompted the second rapid update to the guideline? Dr. Beverly Moy: Thank you very much for that question, Brittany. The guidelines committee decided to issue another rapid guideline update because of the second interim analysis results of the TROPiCS-02 trial. This trial showed that sacituzumab govitecan had a significant improvement of over three months in overall survival compared to chemotherapy of physician's choice in patients with pretreated metastatic hormone receptor positive and HER2/neu-negative breast cancer. So we felt that the strength of this data compelled the ASCO guideline ommittee to issue yet another update. Brittany Harvey: Understood. So then, based off this strong data that you just mentioned from TROPiCS-02, what is the updated recommendation from the guideline expert panel? Dr. Beverly Moy: So the guidelines expert panel really wanted to get this information out because we felt compelled that clinicians should be aware that sacituzumab govitecan is another treatment option for patients with endocrine-resistant metastatic hormone receptor- positive and HER2-negative breast cancer. So we felt that clinicians may use this drug in patients who have received at least two prior treatments in a metastatic setting. Brittany Harvey: Okay, you just mentioned this is one of several treatment options. So as this new recommendation is implemented, what should clinicians know? Dr. Beverly Moy: So, I think that clinicians really need to be aware that sacituzumab govitecan, which is a newer drug, as an antibody drug conjugate, it really does have a role in patients with metastatic hormone receptor positive, HER2/neu-negative endocrine-refractory breast cancer. I think clinicians have been used to this drug in the setting of metastatic triple-negative breast cancer, but the results of theTROPiCS-02 trial would show us that it actually has a lot of efficacy and even an overall survival benefit in patients with metastatic hormone receptor-positive breast cancer. So clinicians should be made aware that this is a treatment option that does give an overall survival benefit. Brittany Harvey: Great. It's great to hear that there's an overall survival benefit with this drug. So, in addition to that, how does this rapid update impact patients with hormone receptor-positive HER2-negative metastatic breast cancer? Dr. Beverly Moy: So I think that it's important for clinicians to remember that patients with metastatic hormone receptor-positive HER2/neu-negative breast cancer, the first-line therapies are endocrine therapy and targeted therapies. But when their disease becomes endocrine refractory, we have several treatment options, and usually the standard is sequential single-agent chemotherapy. What this guideline update is telling us is that sacituzumab govitecan, when compared to other treatments of physician's choice, really does improve overall survival and progression-free survival. So it really should be considered. Brittany Harvey: Excellent. And then finally, are there ongoing research developments that the panel is keeping an eye on for any future updates to this guideline? I know this guideline was last published in 2021 and there's already been two rapid updates to it. Dr. Beverly Moy: Yes, that's a really great question, Brittany, because this is a very active field, and I think that it's important actually to take this guideline update with sacituzumab govitecan in the context of our last guideline update, which, as you said earlier, was with the other antibody drug conjugate trastuzumab deruxtecan. That was our last guideline update in patients who had what we call metastatic HER2 low disease, where trastuzumab deruxtecan had a significant overall survival advantage as well. So what these two guideline updates are really pointing out is that there's this new class of drugs, these antibody drug conjugates, that have so much promise and so much activity in metastatic breast cancer, whether it's hormone receptor-positive or hormone receptor-negative. So future research really has to help us clarify how do we sequence these drugs most appropriately now that we have these two very active treatment options that have a significant overall survival advantage. And then research also has to really guide us into the resistance mechanisms that may be in common or not in common with these two antibody drug conjugates. So I think that we're really looking at results of future trials to see how best to sequence them, if they should be used earlier in treatment in the metastatic setting, and we await the results of those trials. Brittany Harvey: Absolutely. We'll look forward to those future research developments and work with you and the panel to continuously update these guidelines. So I want to thank you so much for your work leading these guideline rapid recommendation updates, and thank you for your time today, Dr. Moy. Dr. Beverly Moy: Thank you, Brittany, for having me. Brittany Harvey: And thank you to all our listeners for tuning in to the ASCO Guidelines podcast series. To read the full guideline, go to www.asco.org/breast-cancer-guidelines. You can also find many of our guidelines and interactive resources in the free ASCO Guidelines app available in the Apple App Store or the Google Play Store. If you have enjoyed what you've heard today, please rate and review the podcast and be sure to subscribe so you never miss an episode. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity or therapy should not be construed as an ASCO endorsement.
We have been dreaming of a world with more equality, more authenticity, more peace, more receiving. Oh and this new earth is not in 5D……….what?It's true the frequencies of 1D to 7D are just not gonna cut it. Actually, this has already been tried (think Atlantis) and it didn't work. The equations for those Dimensions have already been corrupted and will not get humanity anywhere except for destruction. So, the new earth will be created using 22nd dimensional frequencies which requires a new central sun and new star system. We will be aligning the Earth Gate in Peru to the new central sun. ( https://angelablaha.com/peru )There are a few things that will make your shift to the new consciousness easier. If you do not believe that everything is energy, frequencies and vibrations I highly suggest you do some research. In the new consciousness this is the only thing that exists. And to make the transformation, paying attention to your vibration is imperative. Here are 3 things to focus on vibrationally. Endocrine system - the new communication system. In the new frequency the endocrine system will be how we communicate. In the old system we believed we communicated with the Amygdala, not any more. We will be connecting and communicating with the carbon based body. This will help with deeper intuition and will create an even playing field with information and evolution.Neutrinos - the new package of information. In the past we have used the telomeres to receive photon light to feed the body. In the new frequency this is too slow of a process so we will be using neutrinos to feed the body. Since neutrinos move faster than light the body will need a bit of time to make the transition so you can expect tiredness, confusion and a feeling of floating in the abyss.The New Frequency - Assignments versus purpose. This is probably the biggest change to the way you view life. We no longer will have a life purpose, instead we will have assignments that will change frequently. Since we are using the entire body as a communication board it will be easier to understand intuition and will be more clear. No more guessing. This is a little about the new earth, there is always more to come but just wanted to let you know how to get started in shifting. If you are struggling or would love a guide to help you work through these shifting times I have put the Soul Mentoring Program on a subscription. The price will be $99 per month if you subscribe now. Here is the link - https://angelablaha.thrivecart.com/soul-purpose-mentoring/Support the showThis is Angela Blaha signing off from the cosmos. Please check out my website at: Angelablaha.com on my latest offerings. Please like and subscribe so we can grow and reach more people for this amazing shift in consciousness we are experiencing.
The Endocrine Society made news recently by launching a new, online-only, open-access journal called JCEM Case Reports, which is dedicated to clinical cases in endocrinology. What can we learn from case studies, and what does this journal have to offer? To answer those questions, host Aaron Lohr talks with JCEM Case Reports Editor-in-Chief William F. Young Jr., MD, the Tyson Family Endocrinology Clinical Professor and professor of medicine in the Mayo Clinic College of Medicine at Mayo Clinic in Rochester, Minn. For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast
Naomi Love shares the role of the space holder to be trauma-informed and create a safe environment for healing work to happen. You'll also hear about: What is somatic womb healing? Creating space for integration What happens when facilitator training is not trauma-informed Cultivating resilience to meet what arises ♥♥♥ Join The Earth Speak Collective Membership! Join like-hearted folks in a sacred container and community where you'll: Connect deeply to yourself, others, nature & spirit Learn to trust your intuition Activate your Earth magic Expand your healing & divination skills Put your intuition into practice in everyday life Stop feeling lonely on your spiritual path Embody & express your creative power & truths Experience safe space without agenda or judgment When you join the Collective, you get access to all of our past workshops, any live workshops happening while you're a member, live weekly energetic reset calls, monthly community rituals, all the secret episodes, member-run meetups to explore magical topics, and a lively members-only forum (that's not on FB!). ▶▶▶ Learn more and sign up for the Collective membership here: https://www.earthspeak.love/collective ***** Naomi Love helps people to track patterns that keep them held in repeating disharmonious cycles in the way they think, feel, experience and relate with life. She guides people home to their true nature and share with the KEY's to setting themselves free from the old paradigms. In this replay episode, Naomi shares about what is womb healing and how to facilitate ceremony in a trauma-informed way. Access to the Temple of the Womb Apprenticeship closes on January 11th, 2023. Learn more and connect with Naomi at the Wise Womb Medicine Path and at www.naomilove.org. In this episode, we talk about: Living on the diverse lands of Hawaii What is somatic womb healing and how Naomi developed her teachings Tracking patterns and trauma within the body Getting out of the mind and into the body Differentiating between emotion and the ego Learning to receive and relate in healthy ways The stomach as the most vulnerable aspect of the body The role of the space holder in creating a safe environment for healing work to happen Why do womb work? Agency vs power over The miracle of birth and creating life Healing ancestral trauma Feeling out of resonance with your truth What happens when facilitator training is not trauma-informed Creating safety for yourself and others with energic hygiene Why opening space is different to holding space Toxic positivity Cultivating resilience to meet what arises Getting to the root of your trauma Bringing the focus back to healing Creating space for integration Being in right relationship with your role as a facilitator Learning to feel safe with touch in a non-sexual way Feeling connected to the cosmic web of creation Coming back to your true nature How Naomi came to study and teach womb work and cacao ceremony Communing with plants Honoring the spirit of the medicine of cacao Ask the Oracle Getting clear on your offerings And more! Secret Episodes! Get access to past secret episodes at https://www.earthspeak.love/secret. Earth Speak Links: Join the Earth Speak Collective Membership at https://www.earthspeak.love/collective Become an Earth Speak Sponsor and reach more of the people you're meant to serve www.earthspeak.love/sponsor Support the Earth Speak Podcast and purchase our t-shirt Support Earth Speak and make a donation Get the secret episodes at https://www.earthspeak.love/secret Guest Links: Learn more about Naomi's offerings at www.naomilove.org Learn more about the Wise Womb Medicine Path at www.wisewombmedicinepath.com Connect with Naomi on Instagram @wisewomboracle // https://www.instagram.com/wisewomboracle/ Connect with Naomi on Facebook @wisewombmedicine Temple of the Womb || Training https://www.wisewombmedicinepath.com/womb-temple References: Native Land https://native-land.ca/ Episode 52 || Naomi Love https://www.earthspeak.love/shows-1/naomi-love-42 Episode 2 || Naomi Love https://www.earthspeak.love/shows-1/naomi-love-intuition-orientation Fae folk https://en.wikipedia.org/wiki/Fairy Somatic experiencing https://en.wikipedia.org/wiki/Somatic_experiencing Law of attraction https://en.wikipedia.org/wiki/Law_of_attraction_(New_Thought) Endocrine system https://en.wikipedia.org/wiki/Endocrine_system Buddhism https://en.wikipedia.org/wiki/Buddhism Dalai Lama https://en.wikipedia.org/wiki/Dalai_Lama Ego https://en.wikipedia.org/wiki/Id,_ego_and_super-ego Gaslighting https://en.wikipedia.org/wiki/Gaslighting The Tracker || Book https://amz.run/5Z8n Bodywork https://en.wikipedia.org/wiki/Bodywork_(alternative_medicine) Shamanism https://en.wikipedia.org/wiki/Shamanism Clinical nutrition https://en.wikipedia.org/wiki/Clinical_nutrition Herbalism https://en.wikipedia.org/wiki/Herbal_medicine Tantra https://en.wikipedia.org/wiki/Tantra Ibu Robin http://iburobin.com/ Ecstatic dance https://en.wikipedia.org/wiki/Ecstatic_dance Nine Perfect Strangers || Mini-series https://en.wikipedia.org/wiki/Nine_Perfect_Strangers_(miniseries) Epigenetics https://en.wikipedia.org/wiki/Epigenetics Human Design https://en.wikipedia.org/wiki/Human_Design ADHD https://en.wikipedia.org/wiki/Attention_deficit_hyperactivity_disorder Eckhart Tolle https://en.wikipedia.org/wiki/Eckhart_Tolle Restoring the Kinship Worldview || Book https://amz.run/5aDj Episode 67 || Kat lee https://www.earthspeak.love/shows-1/kat-lee-67 Yoni https://en.wikipedia.org/wiki/Yoni Temple of the Womb || Training https://www.wisewombmedicinepath.com/womb-temple Cacao https://en.wikipedia.org/wiki/Cocoa_bean Cacao Facilitator Training https://www.wisewombmedicinepath.com/cacao-ceremonial-facilitator-training Yoni egg https://en.wiktionary.org/wiki/yoni_egg Yoni steam https://en.wikipedia.org/wiki/Vaginal_steaming Ayahuasca https://en.wikipedia.org/wiki/Ayahuasca Peyote https://en.wikipedia.org/wiki/Peyote Non-binary https://en.wikipedia.org/wiki/Non-binary_gender Hysterectomy https://en.wikipedia.org/wiki/Hysterectomy Four seasons https://en.wikipedia.org/wiki/Four_Seasons_Hotels_and_Resorts Resonance Ritual || Mentorship https://www.wisewombmedicinepath.com/resonance-mentorship Fire Heart || Book https://store.bookbaby.com/book/fire-heart Miss Beatrice https://earthcenteredhealingarts.com/about-miss-beatrice Rosita Arvigo https://rositaarvigo.com/ Ann Drucker https://earthcenteredhealingarts.com/about-ann-drucker Domini Ponti - night time call you witch day time Tobacco https://en.wikipedia.org/wiki/Tobacco Ixchel https://en.wikipedia.org/wiki/Ixchel Maiden Mother Crone https://en.wikipedia.org/wiki/Triple_Goddess_(Neopaganism) Daisy Kaye https://www.schoolofbreathmedicine.com/about-daisy-kaye Spirit Weavers https://spiritweaversgathering.com/ Sound healing https://en.wikipedia.org/wiki/Music_therapy Narcissist https://en.wikipedia.org/wiki/Narcissism Gemini https://en.wikipedia.org/wiki/Gemini_(astrology) Connect with Natalie https://natalie.net/ Connect with Shawna https://www.instagram.com/shawna.cason/ ► Leave us a written review on iTunes, and get shouted out on the show! 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In this episode, host Aaron Lohr looks back at the Endocrine Society’s Type 1 Diabetes Fellows Conference, which occurred last year, with two conference presenters talking about developmental challenges in type 1 diabetes, including psychological and social, across the lifespan. Our guests are Linda Siminerio, PhD, professor of medicine at University of Pittsburgh and executive director of the university’s Diabetes Institute, and Jill Weissberg-Benchell, PhD, professor of psychiatry and behavioral sciences at Northwestern University. Dr. Siminerio’s presentation was titled, “Identifying and Confronting Challenging Transitions.” Dr. Weissberg-Benchell’s presentation was titled, “Developmental Perspectives in the Psychosocial Aspects of Diabetes.” Thanks to the conference’s supporters who have made this episode possible through unrestricted, educational grants: Abbott Laboratories, Dexcom, Insulet, Lilly, Medtronic, Novo Nordisk, PreventionBio, and Tandem Diabetes Care. Editor’s note: this interview was recorded in 2022. For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast
Dry skin, also known as xerosis or xeroderma, has many causes, including cold or dry weather, sun damage, harsh soaps, and over-bathing. Unfortunately our age can also cause a decrease in several components in our skin such as collagen, elastin, squalene, What does your skin do anyway??? We tend to focus on the visible signs of aging, but what does our skin do for us? And what changes with age in terms of functional that will not only lead to aging but also susceptibility of skin diseases/ FUNCTIONS: The functions of the skin include: Protection against microorganisms, dehydration, ultraviolet light, and mechanical damage; the skin is the first physical barrier that the human body has against the external environment. Sensation of pain, temperature, touch, and deep pressure starts with the skin. Mobility: The skin allows smooth movement of the body. Endocrine activity: The skin initiates the biochemical processes involved in Vitamin D production, which is essential for calcium absorption and normal bone metabolism. Exocrine activity: This occurs by the release of water, urea, and ammonia. Skin secretes products like sebum, sweat, and pheromones and exerts important immunologic functions by secreting bioactive substances such as cytokines. Immunity development against pathogens. Regulation of Temperature. Skin participates in thermal regulation by conserving or releasing heat and helps maintain the body's water and homeostatic balance. HOW IS IT PUT TOGETHER Anatomy The epidermis, the outermost layer of skin, provides a waterproof barrier and contributes to skin tone. The dermis, found beneath the epidermis, contains connective tissue, hair follicles, blood vessels, lymphatic vessels, and sweat glands. The deeper subcutaneous tissue (hypodermis) is made of fat and connective tissue like elastic fibers, collagen.
In this episode, we review the high-yield topic of Neuroblastoma from the Endocrine section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://anchor.fm/medbulletsstep1/message
In this episode, we review the high-yield topic of Thyroid Storm from the Endocrine section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://anchor.fm/medbulletsstep1/message
In this episode, we review the high-yield topic of Maturity Onset Diabetes of the Young from the Endocrine section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://anchor.fm/medbulletsstep1/message
In this episode, we review the high-yield topic of Endocrine Pancreas from the Endocrine section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://anchor.fm/medbulletsstep1/message
Today, Dr. AnnAlisa Behling shares her own story of conquering infertility and balancing her hormones. After introducing dimethylglycine supplements into her diet she actually accomplished the improbable and conceived in her 40's. Seeing such a dramatic shift in her own health inspired her to help women also suffering from hormonal imbalance. As a naturopathic doctor, she is helping women create balance in their mind, body and spirit to find peace and beauty within. Even if your hormones are perfectly balanced, your gut, how you feel and your beliefs all must coalesce for optimal health. Many women today are struggling to be outspoken about mental and bodily discomfort which leads to prolonged suffering. Most women come to Dr. Behling as a final act of desperation because women are taught that discomfort, pms, infertility, acne and a long list of ailments are a normal part of female life. The more we can speak openly and honestly about the true nature of female health we are uncovering the beauty of the female experience. In this episode, Dr. Behling teaches women how to get in touch with their own intuition. Our cycles are a beautiful superpower that is full of untapped potential. There is no such thing as a normal cycle, so she is teaching women to recognize the beauty of their own daily, weekly or even seasonal hormonal changes. Takeaways: [3:30] How dimethylglycine can help balance hormonal and improve fertility [5:45] Methylation helps you detoxify the body and is vital to hormone production [7:00] A normal menstrual cycles are subjective and vary from woman to woman [10:45] Harmonious gut flora is just as vital for health as balanced hormones [13:00] Endocrine disruptors and Environmental impact on hormonal health [16:40] Finding the equal balance of your mind, body and spirit [18:00] Maximizing your lifestyle to feel comfortable and beautiful in your body [20:30] Berries are a great source of nutritious antioxidants for your skin [22:00] You need to embrace and define your own beauty [25:00] Tapping into your intuition during your cycle to understand your energetic ebbs and flows [27:30] Track and understand how your hormones change seasonally Mentioned in This Episode: https://blog.davincilabs.com/blog/author/dr-annalisa-behling-nd Twitter: “Many women are not diagnosed at all, not even just misdiagnosed but really good testing is hard to find.” [9:32] “People don't understand how the gut has a lot to do with fatigue just because of how those little microorganisms are helping you to create hormones and neurotransmitters.” [12:30] Podcast Disclaimer: https://resources.thespadr.com/the-womans-doctor/#disclaimer
In this episode, we review the high-yield topic of Calcitonin from the Endocrine section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://anchor.fm/medbulletsstep1/message
In this episode, we review the high-yield topic of Parathyroid Hormone (PTH) from the Endocrine section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://anchor.fm/medbulletsstep1/message
In this episode, I interviewed Dr. Scott, a certified strength and conditioning specialist with Ph.D. in Health Science from Trident University. We talked about how men seem to be less masculine and the increase in infertility in today's time. Join us to know how significantly the sperm count declined in the past decades and all about testosterone. Go to www.thestandard.academy/magazine to become one of the first to get my digital magazine for free that'll help you create a kick-ass life. Scott Howell, PhD, CSCS, ABHRT-C is the Clinical Research and Education Director of Optimize U and Professor of Health Science at Optimize U Health Sciences and Colorado State University. Dr. Howell holds a Ph.D. in Health Science from Trident University, a Master of Science in Sport and Health Science from American Military University, a Bachelor of Science in Sport and Health Science from American Military University, and a Mechanical Engineering degree from Forsyth Technical College as well as two additional doctorates. He is a certified strength and conditioning specialist (NSCA-CSCS), periodization strength and conditioning expert (PSC-E), an exercise scientist, and epidemiologist with research interests in periodization training for sports, the long-term harm of performance-enhancing drug use, and endocrine disrupting chemicals exposure. A bit about me (Dr. Orest Komarnyckyj) Dr. Orest Komarnyckyj enjoyed a prestigious career as a periodontal regenerative surgeon moving to a new passion in June 2018. He retired after a 33-year career to pursue new passions. At 70 Dr. Orest has taken on a new role as an Interviewer, Podcaster, and government-certified Old Guy. He streams from his new home in Las Vegas, NV. He lives with his wife of 30 years, Oksana. His status as an empty-nester with two college-employed children has left him with time and energy to share decades of successes, failures, and wisdom. You can connect with Scott here: www.optimizeunow.com Email: firstname.lastname@example.org Timestamp Part 1 (8:54 to 8:59 mute) 00:00 - Precap 00:53 - Intro 02:01 - Guest introduction 05:10 - Attack on masculinity in the society 05:48 - Men's testosterone level 07:15 - The first male analysis 07:29 - 1973-2001 significant decline in sperm count 08:13 - Average decline in sperm count from 1943-1973 was 1.2% per year and 1.3% per year from 1973-1986 10:06 - 52 Mn count drop in Sperm 11:09 - Life acceptancy in males is 7% less at birth 12:00 - Endocrine disruptors in the body 13:00 - Affect on testosterone 14:26 - Commercial Start 14:58 - Commercial End 15:12 - Tests by the scientist 16:10 - How does lower testosterone manifests itself 19:09 - How endocrine disruptors compound pregnant women 21:20 - Men in their 20s &30s showing the low levels of testosterone than men in their 50s 23:35 - Normal is not healthy 25:55 - Male factor infertility 27:47 - Outro
In this episode, we review the high-yield topic of Prolactin from the Endocrine section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://anchor.fm/medbulletsstep1/message
In this episode, we discuss an overview of inpatient management of can't miss endo emergencies. Our esteemed guest, Dr. Sara Markley Webster (Emory University, @smarkleywebster) walks us through identification, workup and management of adrenal crisis, myxedema coma, and thyroid storm. Free CME for this episode at curbsiders.vcuhealth.org Episodes | Subscribe | Spotify | Swag! | Top Picks | Mailing List | email@example.com | Free CME! Show Segments ● Intro, disclaimer, guest bio ● Guest one-liner, Picks of the Week* ● Case 1 from Kashlak ● Adrenal crisis identification, workup and management ● Case 2 from Kashlak ● Myxedema identification, workup and management ● Case 3 from Kashlak ● Thyroid storm identification, workup and management ● Outro Credits ● Written, Produced, and Hosted by: Monee Amin, MD and Meredith Trubitt, MD ● Show Notes, Infographic and Cover Art: Caroline Coleman, MD ● Reviewer: Emi Okamoto, MD ● Showrunner: Matthew Watto MD, FACP; Paul Williams MD, FACP ● Technical Production: PodPaste ● Guest: Sara Markley Webster, MD Sponsor: Locumstory If you would like to learn more about locums visit locumstory.com Sponsor: Pattern Visit patternlife.com/curbsiders to get a free disability insurance quote.
Hypoparathyroidism is a rare condition that is caused by the lack of functional parathyroid glands. The condition can lead to a long list of complications including muscle pain, brain fog, and damage to the kidneys. Amolyt Pharma is developing a therapeutic peptide to treat hypoparathyroidism. We spoke to Mark Sumeray, chief medical officer of Amolyt, about what its like for people living with the condition, why it is difficult to manage with current medical approaches, and why therapeutic peptides offer a compelling approach for hypothyroidism and other endocrine disorders.
Testosterone levels are plummeting worldwide and it's having a major impact on men's health. From decreased cognitive function and sex drive, to increased risk of cardiovascular disease: low testosterone is a real crisis that needs to be addressed. So what's behind this testosterone pandemic? According to Dr. Tracy Gapin, an expert on the topic, there are several factors at play including toxins in the environment and our modern lifestyle. For example, the rise of desk jobs and sedentary lifestyles has taken a toll on men's health, leading to lower testosterone levels. Additionally, exposure to toxins like EMFs and pollutants can also disrupt hormone levels contributing to the problem. Dr. Tracy Gapin is board certified by the American Board of Urology and is a Fellow of the American College of Surgeons. In 2017, Dr. Gapin founded Smart Mens Health, focused on optimizing male performance. He offers a personalized path to helping men maximize sexual health, testosterone levels, and prostate health. Things that can affect testosterone levels Many things can affect testosterone levels, but one of the most significant is the presence of toxins in the body. These toxins can come from many sources, including the environment, food, and even personal care products. One of the most common ways that toxins can affect testosterone levels is by binding to sex hormone binding globulin (SHBG). SHBG is a protein that attaches to hormones like testosterone, and when it does so, it prevents them from being able to enter cells and have their desired effect. This can lead to a decrease in overall testosterone levels. Testosterone levels versus free testosterone Testosterone levels and free testosterone are two very important things to consider when thinking about a man's health. Testosterone is the main male sex hormone, and it is responsible for many things, including muscle mass, bone density, and sex drive. Free testosterone is the active form of testosterone that is not bound to proteins in the blood and can thus enter cells and have a cellular effect. Low levels of testosterone can lead to many problems, such as low energy levels, decreased sex drive, erectile dysfunction, weight gain, and cognitive decline. It is thus important to maintain healthy levels of both testosterone and free testosterone to maintain optimal health. How can men increase their free testosterone As a man, you want to have high levels of free testosterone. This is the testosterone that is not bound to proteins in your blood and is available for your body to use. There are several things you can do to increase your free testosterone levels. First, avoid toxins as much as possible. Endocrine disruptors can interfere with testosterone production and lower levels of free testosterone in the blood. Try to avoid plastics and eat organic foods whenever possible. Second, exercise regularly. Exercise helps to increase testosterone production and can also help to lower SHBG levels. Strength training is especially beneficial for increasing testosterone levels. Third, get enough sleep. Sleep is important for overall health and well-being, and it is also crucial for testosterone production. Finally, try supplementation. Zinc, magnesium, and vitamin B6 are all nutrients that have been shown to boost testosterone levels. You can find these nutrients in supplement form or foods like oysters, dark chocolate, pumpkin seeds, and spinach. In this podcast, you will learn about: The testosterone pandemic Ways to optimize male performance. Tips for maintaining good testosterone levels and prostate health How diagnostics can help identify the cause of low energy and drive in men. And so much more. EPISODE RESOURCES: Website - $500 OFF Coupon Code: himmodel Facebook Instagram Twitter Youtube
In this episode, Aaron talks with Travis Goettemoeller, MD, internal medicine resident at Cleveland Clinic, about an abstract he and a colleague presented at ENDO 2022 about the bone mineral density testing of men for hypogonadism. The abstract is titled, “Lack of Bone Mineral Density Testing in Men with Hypogonadism: A Clinical Conundrum.” For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.
Kent Holtorf, MD, is the medical director of the Holtorf Medical Group(Holtorfmed.com) and founder and medical director of the non-profit National Academy of Hypothyroidism (NAHypothyroidism.org). He is also the founder of Integrative Peptides (IntegrativePeptides.com), dedicated to training physicians about ground-breaking peptide therapies and bringing doctors and patients the highest quality natural bioidentical peptides as supplements with unique delivery systems. Dr. Holtorf is an internationally known lecturer, author, and innovator in cutting-edge research and treatments. He has personally trained numerous physicians across the country in the use of bioidentical hormones, thyroid replacement for complex hypothyroidism syndromes, peptide therapies, immune-modulatory strategies, stem cell, exosome and growth factor treatment, hormone replacement for complex endocrine dysfunction, and innovative treatments of chronic fatigue syndrome, fibromyalgia, Lyme disease, and other chronic infectious diseases, CIRS, neurodegenerative diseases, and many others. He is a fellowship lecturer for A4M. He was the Endocrinology Expert for AOL Health and is a guest editor and peer-reviewer for the medical journals Endocrine, Postgraduate Medicine, and Pharmacy Practice. Dr. Holtorf has published many peer-reviewed endocrine reviews on complex, multisystem, poorly understood conditions. He has demonstrated that much of the long-held dogma in endocrinology and infectious disease is inaccurate. He has been a featured guest on CNBC, ABC News, CNN, Fox News (debated the Fox news medical A-team), Good Morning America, The Today Show, EXTRA TV, Discovery Health, The Learning Channel, Glenn Beck, Nancy Grace, Sean Hannity, and more and quoted in numerous print media including the Wall Street Journal, Los Angeles Times, US News and World Report, San Francisco Chronicle, WebMD, Forbes, among many others.
Endocrine Pearls Evaluation and Credit: https://www.surveymonkey.com/r/MedChat47 Target Audience This activity is targeted toward all physician specialties. Statement of Need Primary care providers may not be aware of the latest diagnosis guidelines in the assessment of patients with either primary or secondary endocrine disorders; additionally many symptoms common to endocrine disorders are experienced by patients without endocrine disorders. Objectives At the conclusion of this offering, the participant will be able to: Summarize the prevalence of endocrine conditions, including the most common conditions. Discuss the latest screening and diagnostic guidelines for frequently treated endocrine conditions seen in the primary care setting. Distinguish between primary and secondary endocrine disorders. Describe updated treatment options for common endocrine conditions seen in the primary care setting. Moderator Monalisa Tailor, M.D. Internal Medicine Norton Community Medical Associates Speaker Lisa Folsom, M.D. Pediatric Endocrinologist Norton Community Medical Associates Moderator, Speaker and Planner Disclosures The planners, speaker and moderator of this activity do not have any relevant relationships to disclose. Commercial Support There was no commercial support for this activity. Physician Credits Accreditation Norton Healthcare is accredited by the Kentucky Medical Association to provide continuing medical education for physicians. Designation Norton Healthcare designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Nursing Credits Norton Healthcare Institute for Education and Development is approved with distinction as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation (ANCC). This continuing professional development activity has been approved for .75 contact hours. In order for nursing participants to obtain credits, they must claim attendance by attesting to the number of hours in attendance. For more information related to nursing credits, contact Sally Sturgeon, DNP, RN, SANE-A, AFN-BC at (502) 446-5889 or firstname.lastname@example.org. Resources for Additional Study: Association Between Area-Level Socioeconomic Deprivation and Diabetes Care Quality in US Primary Care Practices https://pubmed.ncbi.nlm.nih.gov/34964856/ Endocrine Causes of Hypertension https://pubmed.ncbi.nlm.nih.gov/33079272/ Norton Healthcare, a not for profit health care system, is a leader in serving adult and pediatric patients throughout Greater Louisville, Southern Indiana, the commonwealth of Kentucky and beyond. Five Louisville hospitals provide inpatient and outpatient general care as well as specialty care including heart, neuroscience, cancer, orthopedic, women's and pediatric services. A strong research program provides access to clinical trials in a multitude of areas. More information about Norton Healthcare is available at NortonHealthcare.com. Date of Original Release |December 2022; Information is current as of the time of recording. Course Termination Date | December 2024 Contact Information | Center for Continuing Medical, Provider and Nursing Education; (502) 446-5955 or email@example.com
This week, Dr. Prather spends two segments on an explosive COVID update about the planned future of your Health Care Freedoms. Then, our show focuses on the growing mental health care crisis in America and the hope we can offer for anxiety and depression through non-pharmaceutical options. In this episode, you'll learn:—Why you should know about the recent 56-page report, "The Lancet Commission On Lessons For The Future From The COVID-19 Pandemic".—The reason Dr. Prather calls the recommendations of this report "Medical Fascism".—How this report promotes mandates and lockdowns for any future pandemic. And the one bright spot in the report that admits the possibility of COVID being the result of a lab leak. —Why the simulation exercise prior to COVID was eerily accurate in its predictions of what actually happened. —What "Prosociality" is and how your individual Constitutional rights are a threat to that goal. And the international vaccine passport recently agreed to by the Biden Administration and the G-20 nations.—The history of Bach Flower Remedies and the results Dr. Prather sees in using them to help his patients deal with emotional issues and crisis situations.—Why Acupuncture and Auriculotherapy are so important in the treatment of trauma and PTSD. And how the 9-11 first responders who received this kind of treatment were less likely to develop PTSD.—The role heavy metal toxicity (like Copper, Arsenic, and Mercury) plays in mental health situations.—How the balance of your Endocrine system is key to you mental health response. And why taking Adrenal Glandulars can help you deal with stress and anxiety.—The importance of proper diagnostics like bloodwork and hair analysis to determine the root cause of mental health issues. And how Homeopathy, Acupuncture, and Chiropractic are effective drug-free options for mental health issues. http://www.TheVoiceOfHealthRadio.com
This meditation brings healing to all of your physical body systems; Skeletal, Nervous, Lymphatic, Endocrine, Circulatory, Respiratory, Digestive, Urinary, Muscular and Skin. It also bring healing to the seven Auric layers of your energetic body. Because physical health is a combination of so many aspects of ourselves, and to assist with this healing, we call in the Dragons of the Highest Light with their incredible healing energy to give you this healthy boost to your immune system and so much more.
We look at Vosoritide, a promising, potential treatment for children with genetic short stature who do not have chondrodysplasia. Host Aaron Lohr talks with Andrew Dauber, MD, division chief of endocrinology at Children’s National Hospital. Dr. Dauber and colleagues presented about Vosoritide at ENDO 2022. Their abstract is titled, “A Prospective Clinical Trial of Vosoritide in Selected Genetic Causes of Short Stature.” For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.
Dr Emmeline Heffernan talking about Endocrine Emergencies. This talk is part of the Paediatric Emergencies 2022 event. To get your CME certificate for listening to this podcast please visit https://www.paediatricemergencies.com/conference/paediatric-emergencies-2022/
**REALFOODOLOGY PODCAST IS NOW ON YOUTUBE!** Dr. Mona Morstein has been a naturopathic physician for thirty-one years. She sees patients for all types of chronic conditions, but has an expertise in hormonal conditions, such as prediabetes, Type 1 and Type 2 diabetes, thyroid (Hashimoto's and Graves), adrenals, reproductive (in women and men). She is the author of the highly esteemed book “Master Your Diabetes: A Comprehensive, Integrative Approach For Both Type 1 and Type 2 Diabetes.” Topics Covered: Difference between diabetes 1 & 2 Is reversing diabetes an option? Is there a cure to diabetes? Symptoms of diabetes Insulin resistance Nutrient deficiency Obesogens and diabesogens Toxic Chemicals and weight gain Insulin resistance Endocrine disruptions BPAs Plastics Phthalates Herbicides and environmental toxins Importance of sweating Overconsumption of sugar Grains and gluten Glyphosate Are low carb diets good for diabetes? What is considered a low carb diet? The dawn phenomenon Why having a regular exercise regimen is so important A1C Gestational diabetes Check Out Dr. Morstein: Book Online Sponsored By: BiOptimizers www.bioptimizers.com/realfoodology Code REALFOODOLOGY gets you 25% off any order. Higher Dose higherdose.com use code REALFOODOLOGY FOR 15% OFF SITEWIDE Organifi www.organifi.com/realfoodology Code REALFOODOLOGY gets you 20% Off ION - Intelligence of Nature www.intelligenceofnature.com Code REALFOODOLOGY gets you 15% off all one time orders Check Out Courtney: **REALFOODOLOGY PODCAST IS NOW ON YOUTUBE!** Courtney's Instagram: @realfoodology www.realfoodology.com Air Dr Air Purifier AquaTru Water Filter EWG Tap Water Database Further Listening: Glyphosate, GMO's and How To Navigate the Food System with Zach Bush MD
Looking for more information on this topic? Check out the Loop Diuretics brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts. It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Twitter: https://twitter.com/mesage_hub Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including over 800 Rx Bricks. After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.
Listen as Dr. London Smith (.com) and his producer Cameron discuss Multiple Endocrine Neoplasia Type 2B with Thanksgiving guests Lisa (Chase O'Donnell) and Ravella Garibaldi (Frankie G). Not so boring! https://www.patreon.com/join/jockdocpodcast Hosts: London Smith, Cameron Clark. Guests: Chase O'Donnell, Frankie G. Produced by: Dylan Walker Created by: London Smith
Endocrine-disrupting chemicals are pretty much everywhere, and all of us have some level of exposure. Today we will talk about research presented at ENDO 2022 on a group of EDCs called parabens. The title of that abstract is “Parabens Promote Pro-Tumorigenic Effects in Luminal Breast Cancer Cell Lines With Diverse Genetic Ancestry.” Host Aaron Lohr talks with one of the authors of that study, Lindsey Treviño, PhD, assistant professor at City of Hope National Medical Center. They talk not just about the effects of parabens as an EDC, but also about racial and ethnic disparities in risk and mortality, as well as research, and how Dr. Treviño and colleagues address these disparities. For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.
Video for this podcast: https://mehlmanmedical.com/hy-usmle-q-592-endocrine Main website: https://mehlmanmedical.com/ Instagram: https://www.instagram.com/mehlman_medical/ Telegram private group: https://mehlmanmedical.com/subscribe/ Telegram public channel: https://t.me/mehlmanmedical Facebook: https://www.facebook.com/mehlmanmedical Podcast: https://anchor.fm/mehlmanmedical Patreon: https://www.patreon.com/mehlmanmedical
Key Takeaways: There are TEN TIMES the number of bacteria in our body than our own cells and the majority of them are found within our digestive system. The gastrointestinal system contains 90% of the body's happy hormone, serotonin. Most importantly, approximately 70% of our immune system is housed in our gut! Episode Summary: The gut, or gastrointestinal system, is truly a gateway to good health. The gut microbiome is an ecosystem of organisms including bacteria, yeasts, fungi, viruses, and protozoan throughout the digestive tract. Far beyond just digestive health, the following organ systems are also closely related to gut health: Immune system Endocrine system Nervous system Circulatory system Integumentary system Respiratory system Reproductive system "The food pyramid might be out of date and confusing to most." Many find they have refigured their food pyramid for convenience, without understanding the harm they are doing to their bodies. For many, it consists of: Grain at the base; Dairy in the middle; . . . and Sugar at the top. "To be frank, none of these foods have any business being part of your diet at all." In this YOUNGER podcast episode, I will help you wake up to how the majority of our diets are now packaged meals with paragraph-long ingredient lists and labels we can't understand due to convenience. We are all busy and cooking takes time, but if this is your situation, just know you may not be eating real food at all! Here are a couple of alarming facts you should know: The United States Food and Drug Administration (FDA) has approved approximately 3,000 different food additives, preservatives, and colorings without adequate research on safety! The average person ingests over 150 pounds of additives each year! The impact based on the fact that such chemicals that have been allowed into our lives is incomprehensible and might be considered experimental. As we become more and more aware of the consequences of this fake-food lifestyle we begin to recognize it is simply unacceptable! The disturbing facts above point to only a few key factors in the leaky gut epidemic, but I do find they are the bigger ones! Here are a couple of alarming facts: The United States Food and Drug Administration (FDA) has approved approximately 3,000 different food additives, preservatives, and colorings without adequate research on safety! The average person ingests over 150 pounds of additives each year! The impact based on the fact that such chemicals that have been allowed into our lives is incomprehensible and might be considered experimental. As we become more and more aware of the consequences of this fake-food lifestyle we begin to recognize it is simply unacceptable! “This information is only one factor in the leaky gut epidemic, but I do find it one of the bigger ones!” Guest Bio: Dr. Robyn Benson is a Doctor of Oriental Medicine (DOM) who brings an innovative and game-changing approach to today's health care. Robyn offers the most advanced and cutting-edge therapies, procedures, and products designed to renew, restore, and revive health called A.R.T.: Amplified Regenerative Therapies. Dr. Benson, author, speaker, and self-care and Regenerative Medicine* expert, is known by many to be THE health detective with life-changing solutions! She has been the owner and founder of the Santa Fe Soul Center for Optimal Health (now Regenerative Medicine) for close to two decades. For almost 30 years, Dr. Benson has applied her considerable knowledge of acupuncture, platelet-rich plasma (PRP) therapy, herbs, IV therapies, and her love for healthy travel to help patients resolve acute and chronic health challenges and to achieve optimal and sustainable health without the use of pharmaceuticals or surgery. Resources for a Younger Lifestyle: A resource link for all my YOUNGER episodes: https://robynbenson.com/podcasts/ Demystifying Detox (episode # 86) by Dr. Robyn Benson Optimize You Mitochondrial Health and Create Bio Resilience (episode #25) with Shawn Wells Your Gut, Your Health Your Wealth (episode #20) with Dr. Vincent Pedre The Truth About Parasites in America (episode #11) with Dr. Glenn Wilcox Your Health, Your Gut, Your Microbiome, They're All Connected (episode #5) with Ken Brown, MD Your Food, Your Health, Your Wealth (episode #2) with Terry Wahls, MD Quotes: “Gut health doesn't stop at digestion. The health of our gut affects nearly every system in our body!" "Gluten allergies, sensitivities, and intolerances are becoming increasingly more common, “gluten-free” has become the “buzz word” within the health community, and people are finally beginning to understand how dangerous gluten can be for their health." "Much like the additives and preservatives flooding our food supply, pesticides are also a big part of what's on our plates that even a strongest gut can't seem to process and eliminate without help."
Listen as Dr. London Smith (.com) and his producer Cameron discuss Multiple Endocrine Neoplasia Type 2A with special guest Oswald Gatsby (Jessie Keeton). Not so boring! https://www.patreon.com/join/jockdocpodcast Hosts: London Smith, Cameron Clark. Guest: Jessie Keeton. Produced by: Dylan Walker Created by: London Smith
Exclusive content and support: https://www.patreon.com/theemttutor The EMT student will have an understanding of diabetes, sickle cell disease, clotting disorders, and the complications associated with each. EMT students should be able to understand the characteristics of type 1 and type 2 diabetes and be able to list the appropriate steps for assessment and prehospital treatment of diabetic emergencies. Students should also be able to discuss hematologic emergencies, and describe sickle cell disease, hemophilia, thrombophilia, and deep vein thrombosis. Knowledge Domains Describe the anatomy and physiology of the endocrine system and its main function in the body and discuss the role of glucose as a major source of energy for the body as well as its relationship to insulin. Define the terms diabetes mellitus, hyperglycemia, and hypoglycemia and understand the differences between hypo and hyperglycemia to include the signs and symptoms of both. Understand the interventions for providing emergency medical care to both a conscious and unconscious patient with an altered mental status and a history of diabetes who is having symptomatic hyperglycemia or hypoglycemia. Identify the steps the EMT should follow when conducting a primary and secondary assessment of a patient with an altered mental status who is a suspected of having diabetes. Know the indications, and contraindications for giving oral glucose to a patient with a decreased level of consciousness who has a history of diabetes. Know the composition and functions of blood as well as describing the pathophysiology of sickle cell disease, complications, and management of sickle cell disease. Describe two types of blood clotting disorders, and the risk factors, characteristics, and management of each. --- Send in a voice message: https://anchor.fm/thepublicsafetyguru/message
In this episode, we review the high-yield topic of Primary Adrenal Insufficiency from the Endocrine section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets
In this episode, we review the high-yield topic of Glucocorticoids from the Endocrine section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets
In this episode from the Endocrine Surgery team at BTK we discuss how Dr. Yeh built the section of endocrine surgery at UCLA. From Sydney, Australia to Santa Monica, he discusses the risks and challenges involved in becoming a leader in academic endocrine surgery. In this podcast we answer the question “why endocrine surgery,” and mention tips for success at all level of training from medical students to early faculty. Finally, we take a moment to honor and remember Dr. Orlo Clark. Dr. Michael Yeh is a Professor of Surgery at UCLA and serves as Section Chief of the UCLA Endocrine Surgery program which he established. Dr. Masha Livhits is an Assistant Professor of Surgery at UCLA and works in the Endocrine Surgery Department Dr. James Wu is an Assistant Professor of Surgery at UCLA and works in the Endocrine Surgery Department Dr. Na Eun Kim is an Endocrine Surgery Fellow at UCLA in her first year of fellowship Dr. Rivfka Shenoy is a PGY-6 General Surgery Resident at UCLA who has completed two years of research Dr. Max Schumm is a PGY-6 General Surgery Resident at UCLA who has completed two years of research. He is a future endocrine surgeon. Important Papers Krishnamurthy VD, Gutnick J, Slotcavage R, Jin J, Berber E, Siperstein A, Shin JJ. Endocrine surgery fellowship graduates past, present, and future: 8 years of early job market experiences and what program directors and trainees can expect. Surgery. 2017 Jan;161(1):289-296. doi: 10.1016/j.surg.2016.06.069. Epub 2016 Nov 17. PMID: 27866719. Krishnamurthy VD, Jin J, Siperstein A, Shin JJ. Mapping endocrine surgery: Workforce analysis from the last six decades. Surgery. 2016 Jan;159(1):102-10. doi: 10.1016/j.surg.2015.08.024. Epub 2015 Oct 9. PMID: 26456130. Kulaylat AN, Kenning EM, Chesnut CH 3rd, James BC, Schubart JR, Saunders BD. The profile of successful applicants for endocrine surgery fellowships: results of a national survey. Am J Surg. 2014 Oct;208(4):685-9. doi: 10.1016/j.amjsurg.2014.03.013. Epub 2014 Jun 21. PMID: 25048570; PMCID: PMC4639920. Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out other Endocrine Surgery episodes here: https://behindtheknife.org/podcast-category/endocrine/
Listen as Dr. London Smith (.com) and his producer Cameron discuss Multiple Endocrine Neoplasia Type 1 as they listen to the earliest podcast in history. Not so boring! https://www.patreon.com/join/jockdocpodcast Hosts: London Smith, Cameron Clark. Produced by: Dylan Walker Created by: London Smith
Videos: Did Julian Assange's lawyers just EXPOSE this CIA scheme? Redacted with Natali and Clayton Morris (3:23 to 6:46) EXCLUSIVE: UNDERTAKER EXPLAINS “MYSTERIOUS” CLOTTING PHENOMENON! | Louder with Crowder (8:17 – 26:00) Green tea and resveratrol reduce Alzheimer's plaques in lab tests Tufts University, November 2, 2022 Tufts researchers are working to understand what might slow progression of Alzheimer's disease. They have tested 21 different compounds in Alzheimer's-afflicted neural cells in the lab, measuring the compounds' effect on the growth of sticky beta amyloid plaques. These plaques develop in the brains of people with Alzheimer's. The researchers found that two common compounds—green tea catechins and resveratrol, found in red wine and other foods—reduced the formation of plaques in those neural cells. And they did so with few or no side effects. The researchers reported their findings in the journal Free Radical Biology and Medicine. Some of the 21 compounds tested reduced the disease progression by acting as anti-viral agents—slowing Alzheimer's induced by the herpes virus. But finding a compound “that could diminish the plaques regardless of the virus component would be ideal, because that would show that regardless of the cause of Alzheimer's, you might still see some kind of improvement,” says Dana Cairns, GBS12. Cairns is a research associate in the Kaplan Lab in the School of Engineering and led the research. The initial screen found five compounds had “really robust prevention of these plaques,” she says. In addition to the green tea compounds and resveratrol, they found curcumin from turmeric, the diabetic medication Metformin, and a compound called citicoline prevented plaques from forming and did not have anti-viral effects. “We hoped to find compounds that would be harmless and show some level of efficacy,” she said. Green tea compounds and resveratrol met that standard. “We got lucky that some of these showed some pretty strong efficacy,” Cairns said. “In the case of these compounds that passed the screening, they had virtually no plaques visible after about a week.” The discovery is significant because there is no cure for Alzheimer's or a way to prevent its progression, aside from several potential drugs developed by pharmaceutical companies that are still in trials, Cairns says. Compounds like these two that show some efficacy and are known to be safe and easily accessible could be taken as a supplement or consumed as part of one's diet, she adds. High fiber, yogurt diet associated with lower lung cancer risk Vanderbilt University Medical School, October 28, 2022 A diet high in fiber and yogurt is associated with a reduced risk for lung cancer, according to a study by Vanderbilt University Medical Center researchers published in JAMA Oncology. The benefits of a diet high in fiber and yogurt have already been established for cardiovascular disease and gastrointestinal cancer. The new findings based on an analysis of data from studies involving 1.4 million adults in the United States, Europe and Asia suggest this diet may also protect against lung cancer. Participants were divided into five groups, according to the amount of fiber and yogurt they consumed. Those with the highest yogurt and fiber consumption had a 33% reduced lung cancer risk as compared to the group who did not consume yogurt and consumed the least amount of fiber. “This inverse association was robust, consistently seen across current, past and never smokers, as well as men, women and individuals with different backgrounds,” she added. Shu said the health benefits may be rooted in their prebiotic (nondigestible food that promotes growth of beneficial microorganisms in the intestines) and probiotic properties. The properties may independently or synergistically modulate gut microbiota in a beneficial way. Yoga Practice Beneficial to Patients With COPD All India Institute of Medical Sciences Oct. 28, 2022 Patients with COPD who practice yoga can improve their lung function, according to a study by researchers at the All India Institute of Medical Sciences, Department of Pulmonary Medicine and Sleep Disorders. The study found that lung function, shortness of breath, and inflammation all showed significant improvement after patients completed 12 weeks of training. An estimated 24 million Americans may have COPD, which includes chronic bronchitis, emphysema, or both. Patients with COPD have trouble pushing used air out of their lungs, making it difficult to take in healthy new air. Although there is no cure for COPD, a patient's quality of life can be improved by controlling symptoms, such as shortness of breath. The study included 29 stable patients with COPD who received yoga training in a format that included the use of physical postures (asanas), breathing techniques (pranayama), cleansing techniques, (kriyas), meditation, and a relaxation technique (shavasan) for 1 hour, twice a week, for 4 weeks. Following the 4-week period, patients were trained for 1 hour every 2 weeks, with the remaining sessions completed at home. Patients were evaluated on assessment of lung function, breathing, quality of life, and inflammation status. A repeat assessment was done at the end of the 12-week training session. All parameters showed significant improvement at the end of the 12-week period. “We found that yoga can be a simple, cost-effective method that can help improve quality of life in patients with COPD,” stated Dr. Guleria. Iron proposed as cause of heart failure in many heart attack patients Indiana University School of Medicine, November 2 2022. A study published in Nature Communications revealed the discovery of a cause for chronic heart failure that occurs in approximately half of the people who experience a heart attack. “For the first time, we have identified a root cause of chronic heart failure following a heart attack,” lead researcher Rohan Dharmakumar of Indiana University School of Medicine's Cardiovascular Institute announced. Using large animal models, the research team found that in heart attacks in which bleeding within the heart muscle occurs upon restoration of circulation, scar tissue is gradually replaced by fat. The inability of fat to effectively propel blood from the heart can lead to heart failure in survivors of this type of heart attack. “Using noninvasive imaging, histology and molecular biology techniques, and various other technologies, we have shown that iron from red blood cells is what drives this process,” Dr Dharmakumar reported. “When we removed the iron, we reduced the amount of fat in the heart muscle. This finding establishes a pathway for clinical investigations to remedy or mitigate the effects associated with iron in hemorrhagic myocardial infarction patients.” The finding led to a clinical trial to determine the effect of iron chelation therapy to remove excess iron in patients with hemorrhagic heart attack. “While advances across populations have made survival after a heart attack possible for most, too many survivors suffer long-term complications like heart failure,” Indiana University's Cardiovascular Institute physician director Subha Raman, MD noted. “Dr Dharmakumar's breakthrough science illuminates who is at risk and why and points to an effective way to prevent these complications.” DHEA supplementation associated with improved sexual function in women Center for Human Reproduction (New York), October 6, 2022 A report published in the journal Endocrine revealed improvements in sexual function among older premenopausal women who supplemented with the hormone dehydroepiandrosterone (DHEA). In their introduction to the article, authors Vitaly A. Kushnir of the Center for Human Reproduction in New York and colleagues describe their use of DHEA in the treatment of infertile women who had low levels of androgen hormones. “In the process of treating thousands of so-affected infertile women, we noticed that many spontaneously reported improvements in libido, sexual desire and, sometimes, even pain status, leading to the paradoxical situation of women refusing to discontinue DHEA supplementation once they conceived,” they remarked. “When we, in a review of the literature, were unable to find a study that investigated the effectiveness of DHEA on female sexuality in older premenopausal women, this study was developed.” The study included 50 infertile premenopausal women whose age averaged 41 years. The participants supplemented with oral DHEA for a minimum of six weeks prior to starting any other fertility treatments. Serum androgen hormone levels, including DHEA and testosterone, were shown to increase following DHEA supplementation. In comparison with pretreatment scores, FSFI index scores improved by 7%, including a 17% increase in desire, a 12% increase in arousal, and an 8% increase in lubrication. However, among women whose scores were among the lowest 25% of the group, total FSFI scores increased by 34%, which included a 40% increase in desire, a 46% increase in arousal, and a 33% increase in lubrication. Women in this group also experienced a 54% increase in orgasm, greater satisfaction, and less pain in comparison with pretreatment values. Trauma during childhood triples the risk of suffering a serious mental disorder in adulthood, study finds Hospital del Mar Medical Research Institute (Spain), November 2, 2022 A study led by researchers at the Hospital del Mar Medical Research Institute links psychological trauma in childhood with an increased risk of developing some kind of mental disorder years later. Suffering psychological trauma during childhood significantly increases the risk of developing a mental disorder in adulthood. Specifically, as much as three times, according to a recent study, published in the journal European Archives of Psychiatry and Clinical Neuroscience. The study analyses the fourteen reviews and meta-analyses published to date in specialized journals on this issue, and is the first to take into account the full range of existing mental disorders. In total, the studies analyzed incorporate more than 93,000 cases, revealing a direct link between suffering psychological trauma at a pediatric age and the risk of developing a mental pathology later in life. “It is the strongest evidence to date that psychological trauma really is a risk factor for suffering a mental disorder later on,” says Dr. Benedikt Amann, lead author of the study The most common childhood traumas are emotional, physical and sexual abuse, as well as emotional or physical neglect and bullying, although there are many others. Suffering one of these situations damages the brain, causing physical as well as psychological consequences in the form of various disorders. In the case of emotional abuse, the most frequent trauma is associated with the most prevalent disorder in the population, that of anxiety. But there is also a relationship between childhood trauma and other pathologies, such as psychosis, which is linked to all traumas, obsessive-compulsive disorder or bipolar disorder. The risk of suffering from borderline personality disorder increases up to fifteen times in the case of having experienced trauma during childhood. Trauma in adulthood is also associated with a four-fold increase in the risk of a later mental disorder. The researchers point out, however, that there is less evidence for this type of pathology.
In this episode, we talk about an exciting experimental treatment for patients with type 1 diabetes called islet cell transplantation. Host Aaron Lohr talks with David Baidal, MD, assistant professor of medicine at the University of Miami Miller School of Medicine. This episode is made possible through an unrestricted, educational grant from Vertex Pharmaceuticals. For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.
This is a re-posting of Episode 60 due to audio problems with the oriiginal posting. We know how helpful continuous glucose monitors are for individuals with diabetes, but might they be of benefit to individuals with prediabetes? Today host Aaron Lohr will talk with Hisham Farhan, MD, an endocrinology fellow at the University of Maryland Medical Center. Dr. Farhan and colleagues made an oral presentation at ENDO 2022 titled, “Impact of Continuous Glucose Monitoring (CGM) on Lifestyle Modifications in Individuals with Prediabetes.” For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.
This is a re-posting of Episode 59 due to audio problems with the original posting. Fructose is sweeter than glucose and is often added to processed foods as a sweetener, commonly in the form of high-fructose corn syrup. Some studies suggest that fructose consumption may be associated with nonalcoholic fatty liver disease, and some new research, recently presented at ENDO, addresses this issue. Host Aaron Lohr talks with one of the authors of this research, Theodore Friedman, MD, PhD, chairman of internal medicine at Charles R. Drew University of Medicine & Science and professor of medicine at University of California, Los Angeles. Dr. Friedman and colleagues’ oral presentation at ENDO 2022 is titled, “Fructose Consumption in Nonalcoholic Fatty Liver Disease in U.S. Adult Population of NHANES 17-18” (NHANES being a national health and nutrition examination survey). For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.
This is a re-posting of Episode 58 due to audio problems with the original posting. Today we shine a spotlight on a fascinating area of focus within endocrinology that maybe you haven't heard much about: oncoendocrinology. What is it, and how are health providers working together to care for patients who have endocrine conditions and cancer? Host Aaron Lohr talks with Afreen I. Shariff, MD, an endocrinologist at Duke University School of Medicine with expertise in endocrine disease in cancer patients. Dr. Shariff is the founding director of the Duke Endocrine-Oncology Program and an associate director for the Cancer Treatment Toxicity Program at the Duke Center for Cancer Immunotherapy. She also chairs the oncoendocrinology special interest group with the Endocrine Society, and she is a host of the podcast "Checkpoint NOW." For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.
This is a re-posting of Episode 57 due to audio problems with the original posting. We know that exercise is good for us, but for athletes who run, how might that level of running impact their bones? Host Aaron Lohr talks about new research on this topic presented at ENDO 2022 with one of the study's presenters, Melanie Schorr Haines, MD, assistant professor of medicine at Massachusetts General Hospital. Dr. Haines and colleagues' presentation at ENDO 2022 is titled, "Male Runners Have Impaired Tibial Cortical Bone Integrity and Strength Compared to Non-athletes." For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.
This is a re-posting of Episode 56 due to audio problems with the original posting. In this episode, Aaron talks with Jennifer Dias from the Icahn School of Medicine at Mount Sinai about gestational diabetes, its association with postpartum depressive symptoms ("maternity blues"), and a predictor that may help prevent gestational diabetes from developing into type 2 diabetes. Ms. Dias, an MD candidate, presented research at ENDO 2022 titled, "Predictors of Postpartum Depressive Symptoms in Women with Recent GDM." For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.
This is a re-posting of Episode 55 due to audio problems with the original posting. In this episode, we talk about a potential marker to help identify youth with type 1 diabetes, islet autoimmunity, and insulin deficiency. This new research was presented at ENDO 2022, and the abstract is titled, "Elevated Serum IgA at Onset of Type 1 Diabetes in Children." Host Aaron Lohr speaks with one of the authors, Amruta Thakkar, MD, of Texas Children's Hospital and the Baylor College of Medicine. For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.
This is a re-posting of Episode 54 due to audio problems with the original posting. We all know how important diet and exercise are to weight loss and maintenance, but what about anti-obesity medications? How efficient are they? Host Aaron Lohr speaks with Michael Weintraub, MD, clinical fellow in endocrinology, diabetes, and metabolism at New York-Presbyterian Hospital/Weill Cornell Medical Center. Dr. Weintraub and colleagues presented in an oral session during the Endocrine Society's annual meeting. The abstract is titled "Long-term Weight Loss Maintenance with Obesity Pharmacotherapy: a 5-Year Retrospective Study." For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.
This is a re-posting of Episode 53 due to audio problems with the original posting. Host Aaron Lohr returns to in-person interviews, starting with the Endocrine Society's 2022 annual meeting in Atlanta. Here he talks about the effects of SARS-COV2 on ovulation with someone we have been talking with since the beginning: Jerilynn C. Prior, MD, professor of endocrinology and metabolism at the University of British Columbia in Vancouver. Dr. Prior and colleagues presented in an oral session during the annual meeting. The abstract is titled "Epidemic of Subclinical Ovulatory Disturbances During SARS-COV2 Pandemic—an Experiment of Nature." For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/podcast.
What is direct specialty care, and why is this model changing healthcare? My guest is Dr. Pérez-Colón, who is on the cutting edge of this work in Puerto Rico. She is the first physician to bring this specialty care to the island. Dr. Sheila Pérez-Colón was born and raised in San Juan, Puerto Rico. She obtained her bachelor's degree in Biology at the University of Puerto Rico, Rio Piedras campus. Her medical education started at the Autonomous University of Guadalajara, Mexico, and she finished with the fifth pathway program at New York Medical College in Valhalla, New York. She completed a 3-year pediatric residency program in the Children's Hospital at Maimonides Medical Center in Brooklyn, NY. She then completed an additional sub-specialty training with a 3-years pediatric endocrinology fellowship at a combined program between Maimonides Medical Center and SUNY Downstate Medical Center in Brooklyn, NY. SUNY Downstate Medical Center then recruited her and Kings County Hospital in NY to become part of their faculty. After years of frustration with the traditional healthcare system (rushed visits, poor accessibility, surprise bills, and long waiting time, which all compromise patient care) and with the realization that nothing is better than being home and helping your people, Elite Endocrine MD was born. https://eliteendocrinemd.com/about IG: Elite.Endocrine.MD_drperez --- Send in a voice message: https://anchor.fm/urcaringdocs/message
Join Susan as she shares a segment from a course she teaches on GI Dysfunction. This clip is dedicated to the Gut-Brain Axis and why the complex interactions can have such a direct effect on the behavior of the movement, endocrine, nervous and visceral systems. It is all about balance and the direct need to make sense of input and the actions necessary. A glance at this episode: [0:40] Susan shares an old story about working top down [1:50] Sympathetic and parasympathetic pathways [2:35] The vagal pathway [3:48] Susan discusses ‘eye brain' vs. ‘old brain' [4:55] The limbic system [6:01] ‘Gut brain' [8:08] An example of serotonin working at its best [10:23] All of the things that can influence the gut Related Links: Kelly McGonigal's Book ‘The Upside of Stress' Tough To Treat Website Erica's Course: Decoding the Complex Patient - Launching in a few weeks. Get on the waitlist now! Susan's Pelvic Health Education Subscription Access the Transcript
Download Transcript ✅ Are you still struggling to control your acid reflux? Have you tried all the suggestions on YouTube with only a little relief or no help at all? In this video, I'll reveal 7 natural and surprising ways to control your acid reflux that many experts don't usually talk about. ✅ CHAPTERS 00:00 Introduction 01:12 7 typical YouTube acid reflux tips 04:18 1. Stress 07:27 2. Making too little acid 09:14 3. Stuffy nose 11:02 4. Treat OSA or UARS 12:24 5. Vitamin D 13:12 6. Low carbohydrate diet 13:28 7. Melatonin ✅ LINKS MENTIONED Love, Medicine & Miracles Upper airway resistance syndrome video Breathing exercises proven to reduce acid reflux Cancer stats US 2014 The effect of psychological stress on symptom severity and perception in patients with gastro-oesophageal reflux Effect of proton pump inhibitor (PPI) treatment in obstructive sleep apnea syndrome: an esophageal impedance-pHmetry study Sleep apnea video Nasal CPAP Reduces Gastroesophageal Reflux in Obstructive Sleep Apnea Syndrome The role of vitamin D in obstructive sleep apnoea syndrome The effect of vitamin D deficiency on eradication rates of Helicobacter pylori infection Vitamin D and stomach gastrin secretion Effects of high doses of vitamin D3 on mucosa-associated gut microbiome vary between regions of the human gastrointestinal tract Solar ultraviolet-B exposure and cancer incidence and mortality in the United States Melatonin for the treatment of gastroesophageal reflux disease; protocol for a systematic review and meta-analysis Non-health benefits of melatonin Reactive Oxygen Species-Induced Gastric Ulceration: Protection By Melatonin The association between severity of obstructive sleep apnea and prevalence of Hashimoto's thyroiditis Role of hypothyroidism in obstructive sleep apnea: a meta-analysis Abnormal thyroid hormones and non-thyroidal illness syndrome in obstructive sleep apnea, and effects of CPAP treatment A Very Low-Carbohydrate Diet Improves Gastroesophageal Reflux and Its Symptoms Melatonin video Endocrine disorders in obstructive sleep apnoea syndrome: A bidirectional relationship ✅ PRODUCTS & SERVICES How you can sleep great, have more energy and mental clarity. Dr. Park's The 90-Day Sleep Diet. Want to un-stuff your stuffy nose? Read the e-book, How to Un-stuff Your Stuffy Nose: Breathe Better, Lose Weight, Sleep Great (PDF) Your Health Transformation Workbook: Refresh, Restore, & Rejuvenate Your Life (online format) Want to have more energy, sleep better, have less pain, and enjoy living again? Reserve a Virtual Coaching session today with Dr. Park ✅ CONNECT WITH DR. PARK DoctorStevenPark.com firstname.lastname@example.org For inquiries about interviews or presentations, please contact Dr. Park through his website at doctorstevenpark.com. ✅ DISCLAIMER This video is for general educational and informational purposes only. It is not to be taken as a substitute for professional medical advice, diagnosis, or treatment. Please consult with your doctor first before making any changes to your health, exercise, nutrition, or dietary regimen. Certain product links above will take you to Amazon.com. If you then go on to buy the product, Amazon will provide me with a small commission, which will not cost you anything.