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Thyroid nodules are common and usually benign, but deciding when and how to intervene is complex. Endocrine surgeons Andrea Gillis, M.D., and Sophie Dream, M.D., along with CRNP Kelly Lovell, explain how they distinguish low-risk cases from those needing treatment. Learn how they help patients choose between monitoring, thermal ablation, and surgery.
Papillary thyroid cancer is the most common type of thyroid cancer, and yet in rare cases, this cancer may originate in locations other than the thyroid glands. In this episode, host Aaron Lohr talks about causes, prevalence, and treatment for papillary thyroid cancer and the rare phenomenon known as ectopic papillary thyroid cancer with Nikita Dhir, MD, of University of Texas Health Science Center at Houston. Dr. Dhir and colleagues presented research at ENDO 2025 in San Francisco titled, “Where Is the Primary Papillary Thyroid Cancer?” Show notes are available at https://www.endocrine.org/podcast/enp101 — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast
Dr. Alex Menze and Dr. Christopher J. Klein discuss whether GLP-1RA usage is linked to radiculoplexus neuropathy and common fibular neuropathy. Show reference: https://www.neurology.org/doi/10.1212/WNL.0000000000213916
Dr. Alex Menze talks with Dr. Christopher J. Klein about the clinical presentation, diagnosis, and management of diabetic lumbosacral radiculoplexus neuropathy and common fibular neuropathy in the context of GLP-1RA. Read the related article in Neurology®. Disclosures can be found at Neurology.org.
Join me and special guest Navy Blue on Saturday, August 30 at Loudmouth in Brooklyn, for the ninth iteration of Reel Talk, a Reel Notes movie night. We'll be screening the 1999 animated sci-fi drama The Iron Giant and talking about his latest album, Memoirs in Armour, his production work on Earl Sweatshirt's latest album, Live Laugh Love, and much more. Tickets and more info here.My guest this week is New Jersey-born rapper, producer, director, and humanitarian, GDP. We spoke about Clive Barker's Nightbreed, the magic of independent movie theaters, Solaris, Highest 2 Lowest, Kids, coming up as a rapper and skater in New Jersey, navigating the blog era, looking back on his old music, reflecting on his decade-long break, co-directing a documentary about rapper Tame One, and the creative process behind he and Fatboi Sharif's EP Endocrine, out now via Fused Arrow Records. Come fuck with us.Endocrine is available wherever music is sold, streamed, or stolen. Consider copping directly from GDP's Bandcamp. Follow GDP on Instagram and Twitter: @g6d6p6. Follow Fused Arrow Records on Instagram and Twitter: @fusedarrowrecsMy first book, Reel Notes: Culture Writing on the Margins of Music and Movies, is available now, via 4 PM Publishing. Order a digital copy on Amazon.Reel Notes stands in solidarity with American immigrants against ICE and the oppressed peoples of Palestine, Congo, Sudan, Tigray, and Haiti. Please consider donating to the Coalition for Humane Immigrant Rights, the Palestine Children's Relief Fund, The Palestinian Youth Movement, The Zakat Foundation, HealAfrica, FreeTigray, and/or Hope For Haiti. For information about contacting your representatives to demand a ceasefire, finding protests, and other tools, check out CeasefireToday!Follow me on Instagram (@cinemasai), Twitter (@CineMasai_), Bluesky (@cinemasai.bsky.social), TikTok (@cinemasai), Letterboxd (@CineMasai), and subscribe to my weekly Nu Musique Friday newsletter to stay tapped into all things Dylan Green. Support the show
In this episode of Onc Now, host Jonathan Sackier welcomes Komal Jhaveri, Breast Medical Oncologist and clinical investigator at Memorial Sloan Kettering Cancer Center, New York, USA. Known for her trailblazing work in HER2-positive, HER2-low, and hormone receptor-positive breast cancers, Komal Jhaveri discusses how molecular subtyping, antibody-drug conjugates, and precision trials are reshaping the field. Timestamps 00:00 – Introduction 02:50 – What initially drew Komal into oncology 04:45 – The future of breast cancer care 06:13 – Possibility of personalised treatments for patients 07:40 – Antibody-drug conjugates 09:30 – How we define HER2 status 14:40 – HER2-low disease 17:40 – Targeted therapy combinations 20:54 – Endocrine resistance 23:18 – The realities of implementing new therapies 28:40 – Promising initiatives on the horizon 31:30 – Komal's key takeaways
Join here for expert analysis of the latest clinical trial data in HR-positive MBC and discussion of the clinical implications of these study results. Credit available for this activity expires: 8/18/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1002835?ecd=bdc_podcast_libsyn_mscpedu
Send us a textIf our visual scoring is still based on gut feeling, how do we scale precision? In this week's DigiPath Digest, I explored four new AI-focused papers that could reshape how we diagnose prostate, bladder, gastroesophageal, and endocrine cancers.From automated IHC scoring to predicting urethral recurrence post-cystectomy, these studies highlight the growing value—and responsibility—of integrating AI into our pathology workflows.And yes, I also reveal where to get my histology-inspired earrings
What is the impact of long-term endocrine treatment for patients? In this special bonus episode, Dr Rebecca Leon explores the menopause-like side effects of endocrine treatment, what GPs can offer to ease these symptoms and how patients can be supported to continue in treatment. GPs Talk Cancer is the podcast from GatewayC, the free early diagnosis resource funded by the NHS and part of The Christie NHS Foundation Trust. This episode is produced by Louise Harbord from GatewayC in collaboration with Listening Dog Media. DISCLAIMER: We know this podcast might be of interest to anybody, however it is aimed at primary care health professionals. All featured statistics are accurate at the time of recording. All views expressed by guest speakers are their own. Subscribe for more expert cancer insights and explore our YouTube series for additional resources. Hosted on Acast. See acast.com/privacy for more information. Hosted on Acast. See acast.com/privacy for more information.
It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: cancer reserach may lead to T1D treatment, GLP-1 oral pill moves forward, Tandem pharmacy moves, Medtronic-Abbott sensor unveield, parents of kids with T1D see income drop, Mannkind submits Afrezza for pediatrics, diabetes scholarships and more! Find out more about Moms' Night Out Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX Cornell researchers have developed an implant system that can treat type 1 diabetes by supplying extra oxygen to densely packed insulin-secreting cells, without the need for immunosuppression. The system could also potentially provide long-term treatment for a range of chronic diseases. This lab has produced previous implantable devices that have proved effective in controlling blood sugar in diabetic mice, but they can only last so long. "It's the proof of concept. We really proved that oxygenation is important, and oxygenation will support high cell-density capsules," Tempelman said. "The capsules are immune protective and last for a long time without having some kind of fouling of the membrane. The body never likes it when you put a foreign substance in. So that's the engineering in the Ma Lab, to look for materials and coatings for the materials that are immune protective, but also don't invoke excess response from the body because of the material." The next step will be to implant the system in a pig model, and also test it with human stem cells. The researchers are interested in eventually trying to use the system for implanting different cell types in humans for long-term treatment of chronic diseases, according to Tempelman, who is CEO of Persista Bio Inc., a new startup she founded with Ma and Flanders that is licensing these technologies. https://medicalxpress.com/news/2025-08-implant-diabetes-oxygenating-insulin-cells.html XX Mayo Clinic cancer research may be big news for T1D. After identifying a sugar molecule that cancer cells use on their surfaces to hide from the immune system, the researchers have found the same molecule may eventually help in the treatment of type 1. Cancer cells use a variety of methods to evade immune response, including coating themselves in a sugar molecule known as sialic acid. The researchers found in a preclinical model of type 1 diabetes that it's possible to dress up beta cells with the same sugar molecule, enabling the immune system to tolerate the cells. The findings show that it's possible to engineer beta cells that do not prompt an immune response In the preclinical models, the team found that the engineered cells were 90% effective in preventing the development of type 1 diabetes. The beta cells that are typically destroyed by the immune system in type 1 diabetes were preserved. https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-researchers-find-sugar-coating-cells-can-protect-those-typically-destroyed-in-type-1-diabetes/ XX A daily pill may be as effective in lowering blood sugar and aiding weight loss in people with Type 2 diabetes as the popular injectable drugs Mounjaro and Ozempic, according to results of a clinical trial announced by Eli Lilly on Thursday morning. The drug, orforglipron, is a GLP-1, a class of drugs that have become blockbusters because of their weight-loss effects. But the GLP-1s on the market now are expensive, must be kept refrigerated and must be injected. A pill that produces similar results has the potential to become far more widely used, though it is also expected to be expensive. Lilly said it would seek approval from the Food and Drug Administration later this year to market orforglipron for obesity and early in 2026 for diabetes. https://www.nytimes.com/2025/04/17/health/pill-glp-1-eli-lilly.html XX Use of diabetes technology has dramatically increased and glycemic control has improved among people with type 1 diabetes (T1D) in the US over the past 15 years, but at the same time, overall achievement of an A1c level < 7% remains low and socioeconomic and racial disparities have widened. These findings came from an analysis of national electronic health records of nearly 200,000 children and adults with T1D by Michael Fang, PhD, of the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, and colleagues. The study was published online on August 11, 2025, in JAMA Network Open. Use of continuous glucose monitors (CGMs) increased substantially from 2009-2011 to 2021-2023, from less than 5% in both children and adults to more than 80% and over half, respectively. While A1c levels did drop over the 15 years, just 1 in 5 children and slightly over a quarter of adults achieved a level < 7%. The average A1c level stayed above 8%, with ethnic minorities and low-income patients seeing the smallest gains. https://www.medscape.com/viewarticle/diabetes-tech-use-rise-a1c-reductions-still-lag-2025a1000lc9 XX Inflammation may predict how well people with diabetes respond to depression treatment, and the effects differ dramatically between type 1 and type 2 diabetes. Diabetes and depression often appear together. Indeed, depression is more than three times more prevalent in people with type 1 diabetes (T1D) and nearly twice as prevalent in people with type 2 diabetes (T2D). When they appear together, treatment for depression can vary widely. In a new study, researchers from the German Diabetes Center (DDZ), the Research Institute of the Diabetes Academy Mergentheim (FIDAM), and the German Center for Diabetes Research (DZD) investigated how inflammation in the body relates to improvement in depression symptoms in people with T1D and T2D. The researchers combined data from three previous German randomized clinical trials that aimed to reduce elevated depressive symptoms and diabetes distress in people with type 1 or type 2 diabetes. Diabetes distress is characterized by feelings of overwhelm, frustration, guilt and worry about diabetes management and its potential complications. A total of 332 participants with T1D and 189 with T2D who had completed both a baseline and 12-month follow-up examination were included in the present study. Measures included depression using the Center for Epidemiological Studies Depression scale (CES-D), blood tests for 76 inflammatory biomarkers, and symptoms broken down into cognitive-affective (e.g., feeling hopeless), somatic (e.g., poor sleep, fatigue), and anhedonia (loss of pleasure) clusters. After adjusting for factors like age, body mass index (BMI), diabetes duration, cholesterol, and co-existing illnesses, the researchers found that in patients with T1D, higher baseline inflammation was linked to smaller improvements in depression. Inflammation seemed to be more connected to physical/somatic symptoms in T1D patients. In those with T2D, higher baseline inflammation was linked to greater improvements in depression. For these patients, the effect was strongest for cognitive-affective and anhedonia – so, emotional and motivational – symptoms. The researchers weren't sure what caused the difference between T1D and T2D, but they suggest it might be due to the different forms of immune activation seen in each condition. That is, autoimmune processes in type 1 and metabolic inflammation in type 2. https://newatlas.com/health-wellbeing/inflammation-diabetes-depression-treatment/ XX Parents of children diagnosed with type 1 diabetes suffer an income drop in the years following the diagnosis. The impact is more pronounced in mothers, especially mothers of children diagnosed in preschool years. And these findings come from a European study.. not the US. Previous research has shown that parents of children with type 1 diabetes are at increased risk of stress-related symptoms and may need to reduce their working hours. "In our study, we observed reduced parental work-related incomes in the years following the child's type 1 diabetes diagnosis. The drop was larger in mothers than in fathers. Since mothers earned significantly less than fathers in absolute terms, even before the child fell ill, the relative drop in mothers was 6.6% the year following diagnosis compared to 1.5% in fathers. We further note the greatest impact on work-related incomes in mothers of children diagnosed at preschool age," says Beatrice Kennedy, physician at the Endocrine and Diabetes unit at Uppsala University Hospital and Associate Professor of Medical Epidemiology at Uppsala University, who led the study. This is a huge study, builds on data from national population and health registers and the Swedish Child Diabetes Register (Swediabkids). The study includes the parents of more than 13,000 children diagnosed with type 1 diabetes in Sweden in 1993−2014, as well as more than half a million parents in the general population who have children not diagnosed with diabetes. The researchers observed that the maternal pension-qualifying incomes (a composite outcome including work-related income and societal benefits) initially increased after the child's diagnosis. This was attributable to mothers applying for the parental care allowance from the Swedish Social Insurance Agency. The parental care allowance was intended to compensate for disease-related loss of work-related income and contribute toward disease-specific costs. When the research team investigated long-term effects in mothers, they found that the pension-qualifying incomes gradually decreased after eight years, and had not recovered by the end of follow-up − 17 years after the children were diagnosed. https://www.news-medical.net/news/20250811/Mothers-face-greater-financial-impact-following-childe28099s-type-1-diabetes-diagnosis.aspx XX The U.S. Department of Justice has reached a settlement with Metro Nashville Public Schools after allegations that the district violated the Americans with Disabilities Act. The parents of a student at the Ross Early Learning Center requested that the school monitor their child's glucose monitor. Investigators found the school refused to do so, despite the child's Type 1 Diabetes diagnosis. As part of the settlement, MNPS agreed to change its policies to allow the use of these devices, ensure trained staff can monitor them throughout the entire school day and at school activities, and improve communication with parents. https://www.wsmv.com/2025/08/12/metro-nashville-public-schools-settles-allegations-it-discriminated-against-students-with-diabetes/ XX Modular Medical has unveiled Pivot, its next-generation insulin patch pump technology aimed at simplifying diabetes care. The company announced its new pump for “almost-pumpers” at the Association of Diabetes Care & Education Specialists (“ADCES”) Conference in Phoenix, Arizona this weekend. It aims for Pivot to target adults with a user-friendly, affordable design. Modular Medical's current pump, the MODD1, won FDA clearance nearly a year ago. It features new microfluidics technology to allow for the low-cost pumping of insulin. The system has a reservoir size of 300 units/3mL. Users can monitor the pump activity with their cell phone and do not require an external controller. The pump uses a provided, single-use, disposable battery. The company announced recently that it validated its insulin pump cartridge line for human-use production in the U.S. Days later, it reported the first human use of the MODD1 pump. Now, it has taken the next steps with the debut of a next-gen pump, set for FDA submission in October. Modular Medical also gamifies diabetes care The company also said ADCES is the place where it will showcase the first playable level of its new Pivot pump gamified trainin module. Level Ex, a developer of medical games, develops the module. Modular Medical said gamification offers a way to make medical training more effective and efficient while improving information retention. Given the complexity in pump uptake, the company hopes to provide an easy way to bring its technology to clinicians and patients. The company expects to have training modules available at the same time as the pump's planned launch in 2026. “Level One is free because diabetes mastery shouldn't come with a price tag,” Sam Glassenberg, CEO of Level Ex, said. “Modular Medical is breaking barriers too – bringing pump therapy to more people through smart, accessible design. Together, we intend to make diabetes management simpler and more inclusive. “People learn best through play – and we believe they want to learn about insulin pumps the same way. In Level One, players aren't just mastering diabetes management through gameplay – they're asking to ‘play' with pumps: to explore how they work, understand their benefits, and build confidence before using them in real life. Our partnership with Modular Medical helps make that possible.” https://www.drugdeliverybusiness.com/modular-medical-unveils-next-gen-insulin-pump/ XX On Tuesday, 12 August 2025, Tandem Diabetes Care (NASDAQ:TNDM) presented at the Canaccord Genuity's 45th Annual Growth Conference, outlining strategic shifts and market focus. The company highlighted its plans for commercial transformation in the U.S. and expansion in international markets, alongside addressing competitive challenges and regulatory impacts. While optimistic about growth in Outside the U.S. (OUS) markets, Tandem is navigating a more competitive landscape domestically. We have entered into the pharmacy channel with Mobi only. And so as Mobi's been building up volume, we're getting experience and we're really learning and understanding what pharmacy offers to us. And the proof points have proved out the thesis I said earlier, which is it can really reduce that barrier for patients, is the out of pocket cost. And so we've decided to accelerate our strategy and where we were starting just with Mobi, we are now moving t slim supplies into the pharmacy channel, and that will kick into gear in the fourth quarter. So as people are looking at the cadence of sales for the remainder of the year with this reframing, many folks are seeing what looks like a a might be an outsized fourth quarter and and having trouble understanding those dynamics. We'll be adding the tSIM supplies to those contracts. We also have more coverage. We will have it in the coming weeks effective this year, so we will be increasing that 30% rate before the end of the year. And then, obviously, everyone's in the same cycle right now already negotiating and discussing their 2026 coverage. And so 30% is the floor. We do expect to continue to grow that coverage in the coming years, and ultimately have a much broader access. Absolutely. It's an exciting technology that allows for us to have an infusion set that extends the wear time from three days to up to seven days. So we're able to use that as part of an independent infusion set, which would then be used with the t slim and with the mobi pump today. But we're also using that same technology as part of the site that's used for mobi when you use it with a tubeless cartridge. So next year, we will launch Mobi in a patch configuration. It uses the same pump that's available today, but by using a modified cartridge, you're able to wear it as a patch pump. So one of the things we announced on the call is that we're using this extended wear technology as part of that site. So what it allows you to do is to change the portion that you wear in your skin separate from the timing of when you change the insulin cartridge. So it allows for that extended wear time, reduction of burden to the patient, which is especially important for higher volume insulin users as we expand into type two. So from here, we will launch the extended wear site next year along with we'll do a separate regulatory filing for the cartridge portion for Mobi that includes this extended wear technology as a predicate device. So that's another filing that we'll need to do, but we have the clearance today for the independent infusion set, but we'll file another five ten k for use of the extended wear technology as part of the tubeless Mobi feature. https://za.investing.com/news/transcripts/tandem-diabetes-at-canaccord-conference-strategic-shifts-and-market-focus-93CH-3834464 XX MannKind today announced a significant regulatory submission and a large financing agreement with Blackstone. The company submitted its lead inhaled insulin product for expanded FDA approval and secured $500 million in funding, it said. First, the Danbury, Connecticut-based company announced that it submitted a supplemental Biologics License Application (sBLA) for Afrezza, its inhaled insulin product, in the pediatric population. MannKind Director of Medical and Scientific Engagement Joanne Rinker, MS, RDN, BC-ADM, CDCES, LDN, FADCES, told Drug Delivery Business News at ADA 2025 that a submission was on the way for children and adolescents aged 4-17 years old. Further data shared at ADA found Afrezza both safe and effective in that age range. Afrezza is a fast-acting insulin formulation delivered through an inhaler device. MannKind engineered the mechanical inhaler device to slowly bring powder into the lung. A small compartment opens for the insertion of the insulin cartridge, then the user closes it. The only other component is a mouthpiece for the sake of cleanliness. Then, the inhalation takes just two seconds. It requires no electronics or extra components. The company expects a review acceptance decision early in the fourth quarter of 2025. “The submission of our supplemental Biologics License Application (sBLA) for Afrezza in pediatric patients is a meaningful milestone for MannKind and people living with diabetes,” said Michael Castagna, CEO of MannKind Corporation. Additional funding provides a significant boost for MannKind MannKind also announced a strategic financing agreement with funds managed by Blackstone worth up to $500 million. The financing provides MannKind with non-dilutive capital to advance its short- and long-term growth strategies. This senior secured credit facility includes a $75 million initial term loan funded at closing. It then has a $125 million delayed draw term loan available for the next 24 months. Finally, it features an additional $300 million uncommitted delayed draw term loan available at the mutual consent of MannKind and Blackstone. The facility bears interest at a calculated SOFR variable rate plus 4.75% and matures in August 2030. “This strategic financing significantly increases our operating flexibility and provides us substantial access to non-dilutive capital on favorable terms, complementing our strong cash position,” said Castagna. “The funding will support the expansion of our commercial team in preparation for the anticipated launch of the pediatric indication for Afrezza, if approved, continued pipeline advancement, potential business development opportunities, and general corporate purposes. Partnering with the Blackstone team on this transaction positions us to accelerate our next phase of growth and innovation.” https://www.drugdeliverybusiness.com/mannkind-fda-submission-pediatrics-500m-blackstone/ XX Medtronic MiniMed Abbott Instinct Sensor [Image from Medtronic Diabetes on LinkedIn] The Medtronic Diabetes business today took to social media to share an early preview of a new integrated Abbott sensor for its insulin delivery systems. Medtronic Diabetes — soon to be MiniMed after its planned separation from the medtech giant – said in the post that the new sensor specifically designed for its own systems is called “Instinct.” “Get a sneak peek at what's coming next: the Instinct sensor,” the business unit's account wrote. “Made by Abbott, the Instinct sensor is designed exclusively for MiniMed systems. We'll share more details about the Instinct sensor when it's commercially available.” The sensor, built on the Abbott FreeStyle Libre platform, reflects “the power of the partnership,” Abbott EVP, Diabetes Care, Chris Scoggins, told Drug Delivery Business News earlier this year. Medtronic and Abbott — two of the largest diabetes tech companies in the world — announced a year ago that they entered into a global partnership pairing Abbott continuous glucose monitors (CGMs) with Medtronic insulin delivery systems. The partnership aims to collaborate on a system based on Abbott's FreeStyle Libre CGMs with Medtronic's automated insulin delivery technology (the latest generation being the MiniMed 780G) and smart insulin pen systems, such as the InPen system. Read more about Medtronic, Abbott and the rest of the diabetes tech industry in our free Diabetes Technology Special Report. Medtronic's systems previously used its own CGMs, such as the Guardian 4 and the Simplera platform, and the company intends to continue using those systems as part of a comprehensive CGM portfolio. Under the companies' agreement, the systems would be sold exclusively by Medtronic — including the Abbott CGM. The companies brought the partnership a step further in April when Medtronic announced the submission of an interoperable pump with the Abbott sensor technology to the FDA. They plan to share more details following the expected FDA clearance, which remains pending. Management also recently emphasized the multi-year nature of the partnership, meaning Medtronic could pair current and future pumps with other Abbott sensors in the future. That could hint at integration with the company's future dual glucose-ketone monitor, as a number of pump makers have already announced collaborations to pair their systems with the sensor once it hits the market. https://www.drugdeliverybusiness.com/medtronic-diabetes-previews-abbott-sensor-minimed/ XX Governor Glenn Youngkin joined Civica officials at the company's Petersburg manufacturing facility to announce a $3 million grant from the Commonwealth of Virginia to accelerate Civica's efforts to develop and produce affordable insulin for Americans living with diabetes. CivicaRx Logo "We are proud to partner with Civica in their mission to make essential medicines more accessible," said Governor Youngkin. "This investment reflects our belief in the power of public-private collaboration to improve lives and strengthen communities." These funds will support the production of insulin aspart, a rapid-acting human insulin analog used to regulate blood sugar in adults and children with diabetes. Civica plans to produce both rapid- and long-acting insulins at its state-of-the-art manufacturing facility in Petersburg, Va., where the company now employs more than 200 skilled workers.1 Over 8 million people living with diabetes need rapid-acting and/or long-acting insulin. The Governor also announced that he had officially proclaimed August 7 – 14 2025 'Life Sciences Week' demonstrating the Commonwealth's commitment to "accelerating the advancement of the life sciences through public-private partnerships, STEM education, workforce development, and sustained investment in research and development." "We are grateful for the Commonwealth's support," said Ned McCoy, Civica's President and CEO. "This funding will help us move closer toward our goal of ensuring that no one has to choose between insulin and other basic needs." Civica and Virginia officials were joined by Lynn Starr, Chief Global Advocacy Officer of Breakthrough T1D, the leading global type 1 diabetes research and advocacy organization. "More than one million American adults live with type 1 diabetes, and many still, sadly, ration their insulin, due to the prohibitively high cost of this necessary medication," said Starr. "Civica's work will help to make insulin more affordable for people across the country." Breakthrough T1D is among more than two dozen organizations and philanthropists, along with the states of Virginia and California, that have partnered with Civica to support the development of affordable insulins. Civica's insulin initiative aims to provide patients with predictable, transparent pricing — no more than $30 per vial or $55 for a box of five pens — regardless of insurance status. About Civica Civica is a nonprofit pharmaceutical company established to address drug shortages. It was founded by a group of U.S. health systems and philanthropies who, after more than a decade of chronic shortages, recognized that the market was not self-correcting and that a different approach is required. Civica works to deliver a safe, stable, and affordable supply of essential medicines to U.S. patients. Media Contact: Liz Power liz.power@civicarx.org +1 860 501 3849 https://cbs4indy.com/business/press-releases/cision/20250807NY46213/governor-glenn-youngkin-announces-3-million-grant-to-support-civicas-affordable-insulin-programs/ XX If you or someone you love is living with diabetes, you already know the fight isn't just medical—it's financial, too. Between daily supplies, doctor visits, and long-term care, the cost of managing type 1 or type 2 diabetes can be overwhelming. Add college or trade school into the equation, and suddenly staying healthy competes with building a future. That's where scholarships for students with diabetes—like Beyond Scholars and others listed here—step in. Whether you're headed to a university, a two-year college, or a hands-on trade program, these opportunities were created to ease the load. Scholarships for students with diabetes Beyond Scholars (from Beyond Type 1): $10,000 for recently graduated high school seniors with type 1 diabetes or type 2 diabetes entering college or trade school. This is one of the largest needs-based diabetes scholarships in the United States. This year, awardees will also receive 6 months of wellness coaching through Risely Health. Applications open: July 25, 2025 Deadline: August 29, 2025 Winners announced: October 2025 https://beyondtype1.org/beyond-scholars-diabetes-scholarships-college-trade-school/ XX Nick Jonas and Kyle Rudolph are using their platforms for a good cause. On Tuesday, Aug. 12, the singer and the former NFL tight end (via his professional fundraising platform Alltroo) announced they're teaming up to launch a rally featuring a fan-coveted prize: a custom 2025 Volkswagen ID. Buzz electric bus that the Jonas Brothers have brought along for their 20th anniversary tour. “Ten years ago, we hit the road with a goal to change what it means to live with diabetes. Since then, Beyond Type 1 has grown into the world's largest digital diabetes community, offering the tools, education, and peer support needed to not only survive but thrive with diabetes,” Jonas, who co-founded Beyond Type 1 (a nonprofit that advocates for those living with diabetes), says in a statement. “We've challenged stigma, built community, provided life-saving resources, and collectively driven global innovation toward prevention and cure. This milestone is a moment to rally even more support for our mission, and partnering with Alltroo helps us do that in a powerful, engaging way.” Related Stories Nick Jonas on Managing His Diabetes: 'The Mental and Emotional Health Aspect Is Really Important' nick jonas Nick Jonas Says He Was Diagnosed with Diabetes After Joe Told Their Parents: 'Something's Really Wrong' Joe Jonas and Nick Jonas attend the amfAR Cannes Gala 30th edition at Hotel du Cap-Eden-Roc on May 23, 2024 For Rudolph, the campaign is about "celebrating Beyond Type 1's incredible work over the past decade, and standing behind their vision of a world where everyone with diabetes — or at risk of it — has access to the knowledge, care and support needed for early diagnosis and lifelong health." While the rally is live on Alltroo.com, fans can also scan QR codes available at all 36 Jonas Brothers concert stops to enter for a chance to win the electric bus. (A winner will be selected on November 14, which is World Diabetes Day.) Jonas, 32, has long been open about his Type 1 diabetes diagnosis at 13 years old. "I had this kind of wrench thrown into things when I was diagnosed and it took a while to figure out how to count carbs to properly dose for insulin and what things would affect me in different ways," he previously told PEOPLE. "When I was first diagnosed, I was sitting in the hospital and was scared to death, honestly, while I was learning about how to manage this new thing I was dealing with," Jonas recalled. "It would have been amazing to have someone to look at at that time to say, oh, this is a person living with it and they're following their dreams. They're doing what they want to do with their lives and not letting it slow them down." https://people.com/nick-jonas-kyle-rudolph-launch-fan-rally-diabetes-awareness-11788684
After seven years, we have reached our 100th episode! For this, we talk about growth hormone deficiency, about causes, prevalence, why some types may become permanent, available treatments, and the importance of adherence to treatment plans. Host Aaron Lohr talks with Sandro Loche, MD, of Bambino Gesù Children’s Hospital in Rome, Italy. Recently, Dr. Loche and colleagues presented research at ENDO 2025 in San Francisco titled, “Adherence to GH Treatment in the Transition Age: A Prospective Study.” Show notes are available at https://www.endocrine.org/podcast/enp100 — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast
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This episode of Take Charge of Your Health, hosted by Corinne Furnari and Carol Peterson, dives deep into the roots of hormonal science by revisiting Dr. Louis Berman's groundbreaking 1922 book, The Glands Regulating Personality. Berman, a pioneer in early endocrinology, proposed that internal glands—such as the thyroid, pituitary, and adrenal glands—not only regulated physical health but were also key to shaping one's personality, intellect, and behavior. In conversation with an AI-generated segment from The Deep Dive, the hosts unpack Berman's ideas, highlighting his belief that underactive or overactive glands could explain mental states, social roles, and even moral character. Although Berman's work is shadowed by some problematic associations with early 20th-century eugenics, the hosts emphasize his groundbreaking vision of a personalized, chemistry-driven understanding of human potential—one that predated modern functional medicine by nearly a century. They contrast these early concepts with today's clinical practices, pointing out how modern medicine often still overlooks the interconnected, systemic nature of hormonal imbalances. This episode invites listeners to reflect on the historical roots of their own health journeys, emphasizing the continued importance of observing the body as a complex, integrated system.
Endocrine disruptors are chemicals that can interfere with the complex system that produces and interacts with our hormones. Research suggests they can affect the reproductive system, our kidneys, and even increase our risk of cancer. There are over 1,000 types of endocrine-disrupting chemicals, according to some estimates, and we are exposed to them daily through things like kitchen utensils and makeup. So how worried should we be about inevitable exposure?Host Elahe Izadi speaks with oncologist Dr. Mikkael Sekeres about the connection between endocrine disruptors and cancer. Dr. Sekeres also shares his advice on steps he takes to avoid these chemicals–and how he puts the risks into perspective.Today's show was produced by Thomas Lu, with help from Rennie Svirnovskiy, who also mixed the episode. It was edited by Ariel Plotnick. Subscribe to The Washington Post here.
In this enlightening episode of Speaking of Pets, we dive deep into the world of endocrine diseases that can affect our beloved furry friends. Our hosts welcome Dr. Liesl Biggie, an expert in veterinary medicine, to discuss important conditions such as diabetes, Cushing's disease, and thyroid disease. We'll unravel the complexities of these ailments, discussing warning signs that pet owners should watch for, such as increased thirst and urination, changes in appetite, and weight fluctuations. Dr. Biggie shares her insights on diagnosis and treatment options, including the latest advancements in medication and management strategies for both cats and dogs. Whether you're a pet owner wanting to learn more about your furry companion's health or simply curious about veterinary medicine, this episode is packed with valuable information and expert advice. Tune in for a blend of education and engaging conversation that will leave you better informed about your pet's well-being! Don't forget to subscribe, like, and share with fellow pet lovers!--What started during the COVID-19 lockdown with one baby gorilla at the Cleveland Zoo has grown into a channel loved by animal fans around the world. I'm a one-person operation—filming, editing, narrating, and sharing the most heartfelt moments of baby gorillas, orangutans, elephants, and other zoo animals. Whether it's Jameela's emotional journey or Clementine's first steps, each video brings you closer to the animals and their stories. If you love watching real animal behavior, learning fun facts, and supporting conservation through storytelling—this is your place! Subscribe to Larry's Animal Safari on YouTube @larrysanimalsafari ---Support our sponsor for this episode Blue Buffalo by visiting bluebuffalo.com. BLUE Natural Veterinary Diet formulas offer the natural alternative in nutritional therapy. At Blue Buffalo, we have an in-house Research & Development (R&D) team with over 300 years' experience in well-pet and veterinary therapeutic diets, over 600 scientific publications, and over 50 U.S. patents. At Blue Buffalo, we have an in-house Research & Development (R&D) team with over 300 years' experience in well-pet and veterinary therapeutic diets, over 600 scientific publications, and over 50 U.S. patents.---All footage is owned by SLA Video Productions.
Podcast summary of articles from the May 2025 edition of the Journal of Emergency Medicine from the American Academy of Emergency Medicine. Topics include HEART score for chest pain, narcotic overdose, airway quality, ED imaging studies, POCUS for soft tissue abscess, and hyperosmolar hyperglycemic state. Guest speaker is Dr. John Bennison.
Featuring an interview with Dr Hope S Rugo, including the following topics: Pharmacologic features of antibody-drug conjugates (ADCs) and implications for their efficacy and toxicity in HR-positive breast cancer (0:00) Clinical and biological factors influencing the sequencing of approved ADCs for HR-positive and triple-negative metastatic breast cancer (4:03) Management of common toxicities with approved ADCs (10:48) Sacituzumab govitecan as first-line therapy for metastatic triple-negative breast cancer (18:17) Trastuzumab deruxtecan in combination with pertuzumab as first-line therapy for HER2-positive metastatic breast cancer (21:09) CME information and select publications
Dr Hope S Rugo from City of Hope Comprehensive Cancer Center in Duarte, California, discusses the efficacy and safety of approved and investigational antibody-drug conjugates for endocrine-resistant HR-positive and triple-negative metastatic breast cancer. CME information and select publications here.
Featuring a slide presentation and related discussion from Dr Hope S Rugo, including the following topics: Current treatment landscape for and outcomes in HR-positive, HER2-negative metastatic breast cancer (mBC) (0:00) Trastuzumab deruxtecan for HER2-low and HER2-ultralow mBC (7:49) Sacituzumab govitecan for HR-positive, HER2-negative mBC (20:44) Datopotamab deruxtecan for HR-positive, HER2-negative mBC (27:29) Novel antibody-drug conjugates under investigation for HR-positive mBC (33:19) CME information and select publications
In this episode of The Dairy Nutrition Blackbelt Podcast, Dr. Laura Hernandez from the University of Wisconsin-Madison explores key insights on managing hypocalcemia in dairy cattle. She discusses strategies to prevent both delayed and persistent hypocalcemia, as well as the concept of transient hypocalcemia, highlighting their impact on cow health and lactation performance. Learn about nutritional strategies to optimize calcium homeostasis during the transition period. Listen now on all major platforms!"Delayed hypocalcemia is when you have a normal blood calcium concentration within the first two days postpartum, but then at four days postpartum, it becomes clinical or subclinical hypocalcemia."Meet the guest: Dr. Laura Hernandez is a Professor of Lactation Biology at the University of Wisconsin-Madison, where she directs the Endocrine and Reproductive Physiology Graduate Program. With a Ph.D. in Nutritional Sciences from the University of Arizona, her research focuses on calcium homeostasis during lactation and preventing milk fever in dairy cattle.Click here to read the full research article!Liked this one? Don't stop now — Here's what we think you'll love!What will you learn: (00:00) Highlight(01:47) Introduction(02:09) Dr. Hernandez's background(02:55) Preventing hypocalcemia(05:12) Transient hypocalcemia(08:17) Dietary strategies for prevention(09:15) Calcium binders and phosphorus(12:35) Closing thoughtsThe Dairy Nutrition Blackbelt Podcast is trusted and supported by the innovative companies:* Kemin* Afimilk* Adisseo* Priority IAC- Zinpro- Virtus Nutrition
Hair loss in women can be more than just a cosmetic concern it's often a sign that something deeper is going on with your health. Things like thyroid issues, low iodine levels, and even the aftereffects of COVID can all play a role. Many women also deal with low energy and mood changes that tie back to hormone imbalances and nutrient deficiencies.Getting the right lab work done is an important first step, especially if you've only ever had basic thyroid tests. A more complete look at your hormones, minerals, and gut health can help you figure out what your body really needs. With the right support, it's possible to feel better, have more energy, and start seeing improvements not just with your hair, but your overall well-being too.Highlights of the Podcast00:04 - COVID's impact on the thyroid00:45 - Detox, kill parasites, and restore balance02:12 - Support adrenal and testosterone function03:28 - Hidden iodine deficiency from diet04:34 - Endocrine disruptors in food, water, and air07:10 - Consequences of long-term deficiencies08:36 - Emotional signals and undiagnosed issues09:59 - COVID's long-term thyroid damage11:36 - Hormone disruption in younger adults
Please join us to experience the consciousness and healing energies of the InterGalactics to revitalize the endocrine system, hormones, and glands in our body. Known as our inner pharmacopeia, the endocrine organs and hormones released by these glands are vital for our overall health and vitality. We start out with a 50 minute healing session using all the downloaded InterGalactic Healing energies from all four levels to balance, heal, and revitalize the endocrine system. We systematically go through the following endocrine glands:-Hypothalamus-Pituitary-Pineal-Thyroid-Parathyroid-Thymus-Pancreas-Adrenals-Testes/OvariesWe also balance all seven subtle body layers (physical, etheric, emotional, mental, causal, spiritual, and divine) as they relate to the endocrine system.
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Recently the Endocrine Society’s Bone and Mineral Special Interest Group discussed the importance of fracture liaison services and how they contribute to an improved quality of life for patients and cost saving for the facility. An important part of the discussion revolved around a recent perspective published in The New England Journal of Medicine titled, “Coordinating Multidisciplinary Care — Improving Outcomes after Fragility Fractures.” The article notes that despite the benefits of fracture liaison services, the lack of reimbursement for those services in the United States is a significant financial barrier, rendering the service underutilized. The article further states that the global burden of hip fractures is expected to double over the next few decades. Are we looking at an impending crisis? What role should fracture liaison services play in reducing treatment gaps and improving post-fracture care? Host Aaron Lohr talks with the three authors of that New England Journal of Medicine perspective: Nicola Napoli, MD, PhD, associate professor of endocrinology and metabolism at Campus Bio-Medico University of Rome, Italy; Peter Ebeling, AO, professor medicine at Monash University in Melbourne, Vic., Australia; and Douglas P. Kiel, MD, professor of medicine at Marcus Institute for Aging Research at Hebrew Senior Life. Show notes are available at https://www.endocrine.org/podcast/enp99 — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast
In this conversation, Dr. Tracy Gapin and I discuss the critical connection between health and success, particularly for men. We explore common blind spots in men's health, the importance of proactive testing, and the role of technology in tracking health metrics. How hormones, blood sugar, inflammation, and environmental factors can impact your overall health. Dr. Tracy Gapin discusses the critical role of testosterone replacement therapy in men's health, emphasizing the importance of addressing underlying health issues and lifestyle changes. He explores various options for testosterone replacement, the use of peptides for health optimization, and effective strategies for managing stress and blood sugar levels. Takeaways:Success in every area starts and ends with your health.Many men discount their health, thinking they're fine.Testing can reveal blind spots in health that need attention.Wearable technology can help track daily health metrics effectively.Low testosterone is correlated with increased cardiovascular risk.Endocrine disruptors in the environment significantly affect testosterone levels.Men need to adopt a proactive approach to their health.Stress has a major impact on testosterone production.Lifestyle changes can naturally boost testosterone levels.Peptides can enhance health but should not replace foundational health practices.Stress management techniques like box breathing can lower cortisol levels.Nutrition, particularly protein intake, is vital for men's health.Blood sugar regulation is often linked to diet and lifestyle choices.Finding your unique ability can transform your professional life.Intentional living and daily microhabits can lead to significant health improvements.Links: DERRICKTikTok:https://www.tiktok.com/@drderrickInstagram:https://www.instagram.com/derrickbhines/Youtube:https://www.youtube.com/@DrDerrickDr. TracyWebsite: https://drtracygapin.com/ LinkedIn:https://www.linkedin.com/in/tracygapin/
You may be experiencing menopausal symptoms and side effects due to taking medications such as tamoxifen and aromatase inhibitors, also called endocrine therapy. You may wonder how much longer you can go on like this. And you may not know what your true benefit of being on these medications is for you. So in today's conversation, Dani is joined by breast speciality oncologist Dr Claire Macaulay, who looks after patients in a busy NHS hospital in Scotland. Dr Macaulay helps us understand how you can find out and what it means for individual patients.Dani and Claire are also joined by a large group of our community who get to ask their questions and share how they are feeling.Dr Macaulay explains:How oncologists work out the individual's benefit of endocrine therapyThe difference between the older and the new version of the PREDICT toolWhy patients don't just base decisions on facts aloneWhat can we do if symptoms persist?During the episode, Dani shares some helpful podcasts for you to help manage your symptoms. - If you are listening to the podcast, start at Episode 141.- If you are watching on Youtube, start here and work your way up.A huge thank you to Dr Macaulay who is also a certified sex coach, supporting people in menopause to have improved sex lives. You can find her here https://www.pleasurepossibility.comEpisode Highlights:00:00 Intro08:16 Treatment Completion Challenges18:55 Hormone Therapies25:06 Managing Cancer Treatment Information Overload27:59 PREDICT Score for Treatment Outcomes35:55 Endocrine Therapy Concerns: Side Effects40:13 Assessing Tamoxifen: Risks and Benefits50:29 Managing Fear for Better Recovery55:05 Balanced Living for Well-being01:02:16 Recovery Requires Realistic Expectations01:04:20 Medication Assessment TimelineConnect with us:For more information and resources visit our website: www.menopauseandcancer.org Or follow us on Instagram @menopause_and_cancerJoin our Facebook group: www.facebook.com/groups/menopauseandcancerchathub
In this episode of The Fertility Podcast, Natalie sits down with Sian Louise, founder of OBVS Skincare, to explore how one woman turned personal loss, infertility, and cervical cancer into a mission to create safe, effective, and hormone-friendly skincare. Sian opens up about her fertility journey, including multiple miscarriages, the emotional impact of IVF, her cancer diagnosis, and how hormonal acne during treatment became the catalyst for OBVS Skincare. She also shares evidence-based insights into harmful skincare ingredients, like microplastics and endocrine disruptors, and how they may impact fertility. This conversation is part of the Meet the Makers series, celebrating founders whose lived experience with fertility has inspired impactful, purpose-driven businesses. What We Talk About Sian's IVF journey, miscarriages, and cancer diagnosis How hormonal acne during IVF led to creating OBVS Skincare The lack of awareness around skincare ingredients and fertility What endocrine disruptors are and how they affect hormones How Sian built her certified organic, vegan skincare line from scratch Her passion for educating people on safe alternatives The impact of OBVS products on real families and babies Why advocating for yourself in medical settings is essential Sian's advice for managing skin health during fertility treatment Resources & Links OBVS Skincare website: obvs-skincare.co.uk OBVS on Instagram: @obvs_skincare Sian's ingredient call-outs on Instagram: @sian_louise_obvs Beat the Microbead App: beatthemicrobead.org Studies on skincare ingredients and fertility, including: Parabens in breast tumors (Darbre et al., 2004) Endocrine disruption from butylparaben (Boberg et al., 2010) Prenatal phthalate exposure (Swan et al., 2005) Benzophenone's thyroid effects (Schmutzler et al., 2007) Microplastics in cosmetics (TAUW & ECHA reports) Campaign for Safe Cosmetics report: Not So Sexy Let's Stay Connected DM Natalie on Instagram: @fertilitypoddy Follow Fertility Action: @fertility.actionEmail thoughts or guest ideas: natalie@thefertilitypodcast.com Subscribe on your podcast app to stay updated A Word From Our Sponsor – Proceive We're delighted to be partnering with Proceive this season. Their high-strength fertility supplements for men and women are trusted by healthcare professionals and available in-store at Holland & Barrett or online. Use code FP20 for 20 percent off your order at www.proceive.com
Join AACE Past President and endocrinologist Dr. Susan Samson as she leads a compelling roundtable discussion highlighting the importance of the endocrine care team model. She is joined by nurse practitioner Dominique Uva, physician associate Sonia Bahroo, nurse scientist and diabetes educator Dr. Julia Blanchette, endocrine pharmacist Dr. Diana Isaacs, and nurse practitioner and clinical professor Dr. Chris Yedinak. Together, they explore how multidisciplinary care teams are essential to addressing the growing burden of endocrine diseases such as diabetes and thyroid disorders. Each expert shares how they collaborate across disciplines to improve access, provide patient support, and extend specialist care, especially in underserved communities. Tune in for practical insights, collaborative strategies, and a deeper look into how team-based care can elevate endocrine health outcomes.
In this powerful solo episode, Darin Olien takes you on a deeply personal, poetic, and science-backed journey into one of the most essential — and overlooked — truths of our time: we are not separate from nature. We are nature. From Yellowstone's trophic cascades to the microbes in your gut, Darin weaves together quantum physics, ecology, indigenous wisdom, and modern biology to reveal the truth of our profound interconnectedness. Every choice we make — what we eat, how we shop, what we wear — sends ripples through the web of life. This episode isn't just about the planet. It's about your soul. It's about understanding that what we do to others, animals, and ecosystems, we do to ourselves — biologically, emotionally, and spiritually. What You'll Learn: 00:00 – What if everything truly is connected? 01:00 – Why harming the planet harms your body 01:50 – Yellowstone wolves & trophic cascades 02:40 – The Earth's $125 trillion ecosystem services 03:30 – How pollution weakens nature — and us 04:20 – Your body is a living ecosystem 05:00 – The cost of sanitizing away our immunity 06:00 – Mirror neurons, empathy, and brain resonance 07:40 – Cambridge Declaration on animal consciousness 08:30 – Factory farming, antibiotic resistance, and emissions 09:15 – Indigenous wisdom: “Mitákuye Oyás'iŋ” – All are related 10:00 – Quantum physics and David Bohm's implicit order 10:30 – Aligning with the web of life through action 11:30 – What your food, clothes, and chemicals say about you 12:45 – Endocrine disruption and teenage hormone crashes 14:20 – Earth as a living organism: Steiner and Gaia theory 16:30 – Why biodynamic farming mirrors natural harmony 18:00 – How your small choices affect the planet 20:00 – Meditation, stillness, and nature as healing 21:30 – Why ego wants to disconnect — and how to stop it 22:30 – Every choice generates life… or cuts it off 23:30 – The ripple effect of conscious living 24:30 – Your lettuce, your sunlight, your sacred connection Thank You to Our Sponsors: Our Place: Toxic-free, durable cookware that supports healthy cooking. Use code DARIN for 10% off at fromourplace.com. Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Find More From Darin: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Podcast: Superlife Key Takeaway: “Every decision you make either aligns with the system of life… or cuts you off from it. There is no separation — only the illusion of it. You are nature. You are the web. And your choices ripple through it all.”
Welcome to the podcast with Dr. Brendan McCarthy! This episode takes you deep into the real-world practice of prescribing testosterone therapy for women. This is not a high-level overview—this is a nuts and bolts breakdown: ✅ Who it's for ✅ How it's dosed ✅ What labs to run ✅ What delivery methods are safest ✅ Why it's often done wrong—and how to get it right With over 20 years of clinical experience, Dr. McCarthy shares the insights no seminar or textbook can offer, including the emotional and psychological challenges women face when beginning testosterone therapy, and the very real fears around side effects and community stigma.
In this episode, I sit down with Dr. Nicole Cain to talk about her integrative, trauma-informed approach to anxiety and mental wellness. We explore how anxiety shows up in the body—through our thoughts, hormones, immune system, and gut—and what it takes to truly heal at the root.Nicole shares insights from her book Panic Proof along with powerful tools like EMDR, hormone testing, and Ayurveda. Whether you're navigating anxiety yourself or supporting someone who is, this conversation is packed with practical, whole-person strategies to find calm and reclaim your mental health.Leave Us A Voice Message! | https://telbee.io/channel/4_b9zzx58wdkuwirqkcxwa/Topics Discussed:What is the root cause of anxiety and how can it be healed naturally?How does gut health affect mental health and anxiety?What is Dr. Nicole Cain's approach to managing anxiety with integrative medicine?What is the connection between hormone imbalances and anxiety symptoms?Sponsored By:Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at bewellbykelly.com.AG1 | Get a FREE 1-year supply of Vitamin D3+K2 AND 5 free AG1 Travel Packs with your first subscription at drinkAG1.com/bewell.Jesse & Ben's | Right now, you can visit jesseandbens.com/bewell for a special deal.OneSkin | Visit oneskin.co/BEWELL and use code BEWELL for 15% off your first purchase.Timestamps:00:00:00 - Introduction 00:00:00 – Episode intro with Dr. Nicole Cain00:01:41 – What is anxiety? Root causes explained00:05:49 – Kelly's personal anxiety journey00:09:02 – Understanding the window of tolerance00:10:36 – Anxiety, autonomy, and creative power00:13:22 – Why suppressed emotions intensify anxiety00:14:37 – Dr. Nicole's story of living with anxiety00:19:30 – What is thought anxiety?00:24:32 – Tools to overcome thought anxiety00:26:02 – Endocrine anxiety and stress hormones00:32:21 – Hormonal imbalance, anxiety & HRT00:35:35 – DUTCH testing00:37:21 – Immune system's link to anxiety00:40:34 – Gut-brain axis and mental health00:42:13 – Lifestyle changes for anxiety relief00:43:32 – Dr. Nicole's full intake process00:49:31 – Using Ayurveda and Kapha for anxiety00:51:58 – Exercises to calm anxiety naturally00:57:55 – Brain science: prefrontal cortex vs. lizard brain01:01:55 – Interoception and body awareness01:06:28 – How to become panic proofFurther Listening:Prioritizing Hormonal Health with Dr. Carrie JonesCheck Out Dr. Nicole: InstagramBook - To Shop
In this episode, we review the high-yield topic Thyroid Physiology from the Endocrine section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
In this episode, we review the high-yield topic Aromatase Deficiency from the Endocrine section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
In this episode, we review the high-yield topic Pituitary Physiology from the Endocrine section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
In this episode, we review the high-yield topic Other Thyroiditis from the Endocrine section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
Welcome to the podcast with Dr. Brendan McCarthy! In this episode we dive deep into one of the most misunderstood and debated topics in hormone health: testosterone replacement therapy (TRT) for women. You may have heard horror stories—or glowing reviews. But what's the truth? Dr. McCarthy discusses: - Why testosterone matters for women's health - How it affects brain chemistry, mood, bone density, and even breast tissue - Its role after estrogen-suppressing breast cancer treatments - The difference between safe and unsafe TRT - What your provider should be doing to monitor and manage it effectively Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he's been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Citations: Popma, Arne, et al. "Cortisol moderates the relationship between testosterone and aggression in delinquent male adolescents." Biological psychiatry 61.3 (2007): 405-411 Likhtik, E., Stujenske, J. M., Topiwala, M. A., Harris, A. Z. & Gordon, J. A. Prefrontal entrainment of amygdala activity signals safety in learned fear and innate anxiety. Nat. Neurosci. 17, 106–113 (2014). Brannon, Skylar M., et al. "Exogenous testosterone increases sensitivity to moral norms in moral dilemma judgements." Nature Human Behaviour 3.8 (2019): 856-866.. * M.H.M. Hutschemaekers, R.A. de Kleine, M.L. Davis, M. Kampman, J.A.J. Smits, K. Roelofs,Endogenous testosterone levels are predictive of symptom reduction with exposure therapy in social anxiety disorder,Psychoneuroendocrinology,Volume 115,2020,104612 Barel, E, Abu‐Shkara, R, Colodner, R, et al. Gonadal hormones modulate the HPA‐axis and the SNS in response to psychosocial stress. J Neuro Res. 2018; 96: 1388– 1397. https://doi.org/10.1002/jnr.24259 * Buades-Rotger, M., Engelke, C., Beyer, F. et al. Endogenous testosterone is associated with lower amygdala reactivity to angry faces and reduced aggressive behavior in healthy young women. Sci Rep 6, 38538 (2016). https://doi.org/10.1038/srep38538 Ando, Sebastiano, et al. "Breast cancer: from estrogen to androgen receptor." Molecular and cellular endocrinology193.1-2 (2002): 121-128. Somboonporn, Woraluk, and Susan R. Davis. "Testosterone effects on the breast: implications for testosterone therapy for women." Endocrine reviews 25.3 (2004): 374-388. Donovitz, Gary, and Mandy Cotten. "Breast cancer incidence reduction in women treated with subcutaneous testosterone: testosterone therapy and breast cancer incidence study." European journal of breast health 17.2 (2021): 150. Glaser, Rebecca L., Anne E. York, and Constantine Dimitrakakis. "Incidence of invasive breast cancer in women treated with testosterone implants: a prospective 10-year cohort study." BMC cancer 19.1 (2019): 1271. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com
In this episode, we review the high-yield topic Hypoglycemia from the Endocrine section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
In this episode, we review the high-yield topic Delayed Puberty from the Endocrine section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
In this episode, we review the high-yield topic Hypothalamic / Pituitary Drugs from the Endocrine section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
In this episode, we review the high-yield topic of Thyroid Drugs from the Endocrine section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
In this episode, we review the high-yield topic of Hyperaldosteronism / Conn Syndrome from the Endocrine section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
In this episode, we review the high-yield topic of Vitamin D from the Endocrine section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
In this episode, we review the high-yield topic of Thyroglossal Duct Cyst from the Endocrine section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
In this high yield podcast, I discuss confirmatory testing for a host of endocrine related pathologies. The USMLEs love to test these in familiar and unfamiliar situations that occasionally step out of classic norms. I highlight a few of these scenarios and permutations so you’re well versed and ready to tackle whatever presents on your … Continue reading DIP Ep 602: Endocrine Thinking (Stimulation and Suppression Tests)
In this episode, we review the high-yield topic of Hypoparathyroidism from the Endocrine section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
What if the products you use every day—your toothpaste, your shampoo, your food containers—were silently hijacking your hormones, damaging your immune system, and passing that disruption on to future generations? In this explosive conversation, Darin sits down with Dr. Aly Cohen, triple board-certified physician and founder of The Smart Human, to unpack the shocking reality of unregulated chemicals in our homes, food, and water. Together, they explore the science behind endocrine disruption, the failures of U.S. chemical policy, and how simple daily swaps can radically reduce your toxic burden. This episode is not about fear—it's about power. It's about reclaiming your right to live clean. What You'll Learn in This Episode: 00:00 – Welcome to the show + why this episode matters 01:00 – How a red dog toy changed Dr. Aly's career forever 04:30 – The hidden health hazards in your home right now 06:50 – Endocrine disruptors: the silent chemicals causing massive damage 09:10 – From rheumatology to environmental health warrior 11:15 – Why FDA and EPA aren't protecting your health 13:40 – How "safe exposure levels" are based on outdated science 16:00 – GRAS loopholes: how chemicals are self-approved in the food system 18:20 – “Fragrance” is a legal disguise for 100+ toxic ingredients 20:00 – Immune dysfunction, infertility, cancer—how hormone mimics wreak havoc 23:10 – Her 4 A's Framework: Assess, Avoid, Add, Allow 26:40 – The autoimmune epidemic + the environmental root cause 29:00 – Frozen organic vs. dirty dozen: the smarter grocery strategy 32:00 – Consistency > perfection: why small swaps matter most 34:30 – Dr. Aly's top swaps for cleaning, skincare, and cookware 37:00 – PFAS, microplastics, canned food liners, and takeout wrappers 40:10 – The Progresso Soup study that proved behavior change works 43:00 – How to detox without supplements 46:00 – Teaching detox habits to kids through gamification 49:00 – Your genes aren't your destiny—epigenetics and detox 52:00 – Why we can't wait for regulations to save us 55:00 – What to travel with: filters, skincare, food prep 59:00 – What shocked Dr. Aly the most in her research 1:02:00 – Final thoughts on resilience, power, and your right to clean living Don't Forget... I just launched my brand new program Superlife Supermind. Visit my website https://superlife.com/ to learn more about how you can get rid of stress, improve sleep and overall health today. Thank You to Our Sponsors: Shakeology – Shakeology-All in One Nutrition: Get 15% off with code SUPERLIFE at Shakeology.com. Our Place: Toxic-free, durable cookware that supports healthy cooking. Use code DARIN for 10% off at fromourplace.com. Find More From Dr. Aly Cohen: Website: thesmarthuman.com Instagram: @thesmarthuman Book: Non-Toxic: Guide to Living Healthy in a Chemical World Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences SuperLife Products & Protocols: superlife.com Key Takeaway: "It's not about being perfect. It's about becoming aware—and starting to swap out what's hurting you every single day." – Dr. Aly Cohen
Story at-a-glance Chronic disease is at an all-time high — Modern lifestyle shifts have fueled skyrocketing rates of diabetes, heart disease, obesity and autoimmune disorders Vegetable oils have replaced natural fats — Marketed as a healthier alternative, seed oils high in linoleic acid have contributed to inflammation, mitochondrial dysfunction and metabolic disease Endocrine-disrupting chemicals (EDCs) are everywhere — Found in plastics, pesticides and personal care products, EDCs interfere with hormone function, impacting fertility, thyroid health and cancer risk Lifestyle factors are driving mitochondrial decline — Inactivity, poor diet and lack of sunlight exposure have disrupted natural metabolic processes, which led to energy deficits and chronic fatigue Traditional lifestyles offer a blueprint for better health — Whole foods, natural movement and circadian alignment support mitochondrial function and cellular repair, and reverse modern health declines
Which of the following disorders is MOST likely to be the cause of metabolic alkalosis? Find it all out in the podcast! Be prepared for the NPTE so that you can pass with flying colors! Check out www.ptfinalexam.com/podcast for more information and to stay up-to-date with our latest courses and projects. #Npte #PT #ptboards #crushtheNPTE #study #studygram #spt #ptstudent #ptlife #sptprobs #physicaltherapystudent #physicaltherapy #physio #physiotherapist #ptlife #ptstudentstudy
Today, we're going to discuss some of the causes of low testosterone and the most common low testosterone symptoms. Check out these 6 common low testosterone signs:1. Breast tissue “Man boobs” can be caused by an increase in estrogen and a decrease in testosterone.2. Shrinking testiclesThis is also known as hypogonadism. Testosterone is involved with muscle formation, so if your testosterone is low, you may also notice your muscles shrinking.3. Reduced semen production 4. Decreased body hair This may be most evident in the beard, chest, legs, and the top of the head. 5. AndropauseThis can cause hot flashes and night sweats in men. 6. Excess belly fat This is often caused by insulin resistance. The most common causes of low testosterone include:•High-carb diets•Endocrine disruptors•Microplastics and forever chemicals•Poor sleep •Chronic stress•Wifi•EMFs •Phytoestrogens (soy products)•Low zinc •Statins•Iron overloadYou can help increase testosterone naturally with the following:1. Zinc 2. Magnesium3. Vitamin D 4. Exercise5. Water filters 6. L. reuteri Dr. Eric Berg DC Bio:Dr. Berg, age 59, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.
Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions: Kate: Hi there Stephen !I am a big fan of your work, your book and your podcast! All the way from australia I am working in a pharmacy, and feeling like i'm sanitising my hands, more than I probably need to. Does hand sanitiser contain Endocrine disrupters, and should I consider other options? Thanks heaps! Sonny: Hi Dr Cabral, Around 18 months ago, I noticed hair loss at the front of my hairline. I'm in good health, and the only change has been using an infrared sauna 4-5 times a week. I tried 3 PRP sessions, which helped some regrowth, but the hair is now coarse, brittle, and wiry. A trichologist suggested possible alopecia areata, but no clear diagnosis was made. I've been using biotin, EquiLife Daily Hair Support, a red light cap, derma rolling, and copper peptide serum, but haven't seen much improvement. Are there any tests you'd recommend to investigate this further? I'm considering the Stress, Mood & Metabolism Test. Any advice would be greatly appreciated! Sheena: Hi Dr C! Hope you are well and hope 2025 is treating you and your family well. Quick question, after doing The BIG 5, my IHP2 has recommended that I do a Limited CBO protocol. My question is, because its a Limited protocol, would it be ok for me to do a 'cheat meal' once a week? Or should I still wait for after 21 days to have my first cheat meal? Thank you so much! Spencer: Hello Dr. Cabral, Asking a question for my girlfriend. All of the sudden, during a stressful work time, her shoulder started hurting. She had limited range of motion and pain all day. It made sleeping hard. She works from home and wasn't using it or injuring it during this time, it just kind of started to hurt. She went to the orthopedic and he diagnosed with frozen shoulder, gave her a cortisone shot, and said give it a 3-6 months and it should go back to normal. I'm wondering if you have anything complementary that could be added to this as just waiting doesn't feel like the optimal strategy. Thank you for all you do Kavita: Hello Dr. Cabral, I have a question about my husband's diagnosis and also the history. Looking for some answers from you as you have mentioned several times that everything is curable. This is the diagnosis from the doctor: Right leg numbness in the setting of Common peroneal neuropathy at the head of bula versus right & Lumbosacral radiculopathy at L5, superimposed on likely diabetic Neuropathy: Improving symptoms of right lower lateral leg/foot numbness w/in distribution of both the peroneal and L5 nerve root. No evidence of foot drop/weakness. Mild pain, Gabapentin prn for pain as below. Neuropathy is likely from diabetes, will monitor, appears mild/primarily SF based on recent NCS/EMG above. - gabapentin 100 MG Oral Cap; Take 1 capsule (100 mg total) by mouth nightly as needed Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions! - - - Show Notes and Resources: StephenCabral.com/3333 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
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