Podcasts about Excitation

What if sensitivity isn't a weakness at all — but a personality trait that deserves a place alongside the Big Five?In this episode, host Victoria Theriault explores the fascinating case for making sensitivity the sixth major personality trait. Drawing on the work of Dr. Elaine Aron, Dr. Lacey Parker, and other researchers, she unpacks what it really means to be a Highly Sensitive Person (HSP) and why sensitivity may have been misunderstood for far too long.Summer is here, so you know what this means… DISC as musical instruments

durée : 00:03:23 - Dans le Vaucluse, le coquelicot, cette fleur rouge éclatante, fascine par sa beauté et ses vertus. Du bord des champs aux sols rocailleux, de mai à août, il offre des bienfaits calmants, des usages culinaires et symboliques, tout en restant fragile mais résistant. Vous aimez ce podcast ? Pour écouter tous les épisodes sans limite, rendez-vous sur Radio France

In this episode, we review the high-yield topic of⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Spread of Excitation⁠⁠⁠ ⁠⁠from the Cardiovascular section.Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets

Dr. Deb Muth 0:03What are the answers to your child’s chronic allergies, ADHD, or autism?weren’t just in another prescription, but in restoring balance to their body chemistry. Today’s guest has spent nearly two decades uncovering those answers through integrative and biomedical medicine. That’s a mouthful, isn’t it?Helping children heal when nothing else seemed to work.This is the conversation about science, compassion, and changing the future of pediatric care.Welcome back to Let’s Talk Wellness Now. The show where we uncover the root causes of chronic illness, explore regenerative breakthroughs, and empower you with the practical tools to heal. I’m your host, Dr. Deb, your medical detective, and today’s episode is one every patient should hear.My guest is Dr. Anu Usman Singh, Medical Director of True Health Medical Center in Naperville, Illinois, and the owner of Pure Compounding Pharmacy.And for over 17 years, she has been pioneering evidence-based integrative interventions for children with ADD, autism, allergies, and complex gastrointestinal and metabolic disorders. She’s not only a practicing physician, she’s a researcher who’s investigated copper-zinc imbalances.metallonine dysfunction, biofilm-related infections, vitamin D in pregnancy, and hyperbaric oxygen therapy.Dr. Usman serves on the executive board of TACA, and is a faculty member at MAPS, training other practitioners in pediatric integrative care. So get ready for a conversation that will open your mind and heart to the possibilities of when medicine truly becomes holistic.If you guys can insert the ad in here, that’d be great.Well, welcome back. I’m so excited to have Dr. Usman with me today. I have known her for, oh my gosh, 15, 17 years, something like that. We’re aging ourselves. Anju 02:32Oh, yeah, when we were in our 20s, right? Dr. Deb Muth 02:35Yes, exactly. So, welcome back, and I am so excited for you to be here, because you have literally helped thousands of families over the years.But I’d love for you to share a little bit about your journey, kind of who you are, what drew you into exploring integrative and biomedical approaches for helping children and families. Anju 02:58I think my journey is similar to a lot of you out there, the audience. I mean, we’re looking to help our families, and our kids, and ourselves, and I was doing my residency at Cook County Hospital, downtown Chicago, in the 80s.And I thought, oh my goodness, if I could take care of the sickest patients, then I can take care of anybody. So I came from Indiana, and I went to Cook County, and my children, my eldest daughter, started having, severe allergies and asthma, really, really at a young age.And I went to, like, my residence, and I went to my attendings, and I said, this baby is wheezing. And they told me, babies don’t have asthma.And I said, she has all the symptoms of asthma. She has asthma. And I remember with, in her crib, I would just nebulize her, you know, and I was like, what is going on?And I figured out that she had a lot of food allergies, and I was nursing her, eating the foods that she was allergic to, and back then, in the 80s, you know, we didn’t have the internet, we didn’t have Whole Foods, and I just…being a doctor, and I didn’t even know what to do, and I felt so hopeless. And I thought, gosh, you know, I’m a doctor, I have these, like, skills, I have… people I can talk to, and I still feel so… it’s so difficult. And then this… my particular daughter, the oldest one, her name is Priya, and she developed severe, asthma, and I couldn’t figure it out. She was in junior high. Every time she would walk into the lunchroom, she would have a severe asthma attack.And I’ll be like, what’s going on? What’s going on? I kept her home over the weekend, she was better. I sent her back to school, she was bad again.And we figured it out that it was other people eating peanuts. Dr. Deb Muth 04:54Severe peanut allergy. Anju 04:56And I went to the school, and I said, she…can you, like, put her somewhere else? Can… they said, oh, no, that’s not fair to other kids and their food. And this was in the 90s. Dr. Deb Muth 05:10Yeah. Anju 05:10And so, I just…You know, my heart goes out to families who are struggling to find answers for their kids, and my daughter Priya, the one I told you about, she ended up passing away from a peanut allergy.And so, I’ve just… Dr. Deb Muth 05:26Yeah. Anju 05:27My heart goes out to parents and my own kids and their illnesses.And so I just started working with families, with kids, andIt just kind of grew from there. Dr. Deb Muth 05:40Yeah. Yeah. Yeah, and I think being a mom who went through that yourself, and…was seen but not heard, and turned away from the traditional medical community, you’re forced to start finding answers on your own. And we always feel like we’re on an island by ourselves in the medical world when we’re doing that. Anju 06:01Yeah, I, it was really hard when I found out, you know, about…Integrative medicine, and just different…ideas and approaches to diet and supplements, I thought, how come I wasn’t trained in any of this?And… Dr. Deb Muth 06:21So angry when I learned some of the things that I learned in the beginning. I was like, same thing, like, how did they not teach us this? And then I think, you know, it’s my fault, was I asleep, was I not paying attention, whatever. And then you just realize, like, there’s this whole part of the human body.That they just didn’t teach us. Anju 06:42Yeah, so then I… I, probably like you, we had to learn it on our own. There weren’t, like, classes or any way to learn this stuffAnd I just reached out. There’s a clinic that,I don’t know if you’ve heard of the Pfeiffer Treatment Center? Dr. Deb Muth 07:00No. Anju 07:01Do you know Carl Pfeiffer from the attendees.He has a clinic called the Pfeiffer Treatment Center in New Jersey. It was called the Princeton Brain Bio Center. Dr. Deb Muth 07:12And in the 70s, they did orthomolecular medicine for patients with ADD. Anju 07:18And schizophrenia. Dr. Deb Muth 07:20Mmm… Anju 07:21and depression.And they used to categorize them in 3 categories, and at the time, they called them histopenics, histidelics, and pyrolurics. Dr. Deb Muth 07:31Okay. Anju 07:32Histapenix were low histamine patients.Delix were high histamine patients, and pyrolurics were their own kind of category. We added another category of copper-zinc imbalances, and then we would categorize that population into high histamine, low histamine, pyrolurics, and copper-zinc.Now we talk about under-methylation, over-methylation. Sure. So, under-methylation is the, you know, the high histamine people, they can’t clear the histamine. And the over-methylators are, you know, what we call about low histamine now.And, and then pyrolurics and copper zinc. So…I lost my train of thought, but in the 80s, when I was going through this, in the 90s, I reached out to the Pfeiffer Treatment Center.He’s like, can I calm and just hang out and, like, see what you guys do? Because I need some answers.And I started working there and, started doing research on copper-zinc imbalances, and I did it in children with autism.And that’s how people started coming to me, and I kinda got, like. not famous, but I, you know, the word spread about, okay, we could talk about it, and Dr.Walsh was the, you know, PhD there that did a lot of the research, so we worked together for 8 years. Dr. Deb Muth 09:05Isn’t it crazy to think that we knew about histamine issues way back in the 70s? You know, I got the pleasure of being trained by, environmental medicine doctors. Dr. Wayne Konetsky and Glenn Toth taught me about environmental medicine, and what we called histamine issues that we call it today, mast cell, right? But when I was learning in the early 2000s, it was labeled as chemical sensitivity. And so it was just people that would react to everything, and we really didn’t know why, and they didn’t necessarily have this very specific allergic reaction, but we knew they were reacting, and we would try to treat them, to lower the histamine way back then. And it’s taken all these years, 25 years, to get to a point where we understand mast cell activation now, and histamine issues.And it’s really sad to me that it’s taking this long for us to identify things.And we’ve all got our journey, and I loved back in those days, too, because as I learned, I would call people up and say, hey, I just got a patient from you, and they told me this great story, and I have other people, can I come see what you were doing? And back then, everybody was very open. They were like, yes, please, come, learn. Now everybody’s like, oh, we can’t teach you, we can’t give you our secrets, but…Or pay me $20,000 to come learn with me. But back then, I mean, everybody was just… we were all in the same boat. We were all just trying to learn from each other. Anju 10:36Oh, yeah, oh yeah, and any bit of knowledge you got, you’re like… Dr. Deb Muth 10:41Yes. Anju 10:41God, you know, I learned this piece, and… Dr. Deb Muth 10:43Hmm? Anju 10:44We just kind of built from that. I keep thinking about back then, you know,the under-methylators, over-methylators, copper, zinc, and then I learned about metals.And then, as a physician, I was like, oh, okay, well, there’s mercury in vaccines, there’s aluminum in vaccines, and now I’m seeing these high levels. Dr. Deb Muth 11:04In my patients, now what happens? Anju 11:07And then we started, kind of, trying to get the word out about those things. Dr. Deb Muth 11:13Yeah. Anju 11:13And in 2000, a lot of the people that I knew put out a paper about, you know, mercury. Dr. Deb Muth 11:22And then… Anju 11:22And we all got on the Mercury bandwagon. Dr. Deb Muth 11:25Yes. Anju 11:26And did that for a while, and then we started learning about other things, like mitochondrial issues in chronically ill people, and these chronic infections, like Lyme disease, and so… and then now, you know, understanding mast cell activation, cell danger response. Dr. Deb Muth 11:44On endocrine, and adrenals, and hormones, and… Anju 11:48Yeah. Dr. Deb Muth 11:49biofilms. Anju 11:50Biofilms, I started talking about that in 2007. Dr. Deb Muth 11:54And so then… Anju 11:56It just… it just kind of keeps adding, and keeps adding, and keeps adding, and it’s like…Sometimes you think, how come I didn’t know about this back then? But I feel like it’s a process. Dr. Deb Muth 12:06It definitely is a process, and it’s amazing to seehow many people are researching different things, and they’re all, like, putting a piece of the puzzle together. And I think this is really important for our listeners to understand, is when you see a practitioner and they don’t have all the answers, this is why. It’s very complicated, it’s not black and white. And I’ve had patients over the years say to me, well, why didn’t you say this to me 6 months ago? And the truth of the matter was, I didn’t knowabout it 6 months ago. Like, all of this stuff is just… it’s evolving constantly, and when you’re a practitioner like Dr. Usman and myself, you are learning every single day. Our training has never stopped from the day we stepped into integrated medicine, and you just… you keep learning new things, and sharing new things, and talking to new people, and that’s what expands our knowledge base. Anju 12:57Yeah, the more I learn, the less I feel like I know. Dr. Deb Muth 13:01Yes, me too. Every time I go to a conference, I’m like, how did I not know this? How am I stupid? And I know we shouldn’t say that word and call ourselves that, but sometimes you feel like that. It’s like, how did I not know? Anju 13:14Or you’ll see a patient, and you’ll look at them, and you’re like, how come I didn’t realize this about this particular patient? Dr. Deb Muth 13:20Yes. Anju 13:21Yeah, they present differently, see things differently. I think that’s why it’s good to find a doctor that you trust and that you can work with, because it’s evolving. Dr. Deb Muth 13:31Yes. And, you know, we have those patients that they come, and I get those. I call myself, like, a tertiary care center. Anju 13:38You know, you get those patients that have been everywhere, and seen every doctor, and then they’re like, you’re my last hope, you’re gonna solve all my problems, and…I say to them. We’re a team, like, we’re gonna solve these together, but it takes time for me to unravel this puzzle. Dr. Deb Muth 13:54Excuse me? Anju 13:54And it… and sometimes, you know, there’s a few hits and misses along the way. Dr. Deb Muth 14:00Yup, but if. Anju 14:00If we keep at it, you know, we also say it’s a marathon, not a sprint. Yes. You know, if we keep at it, we can kind of figure it out together. Dr. Deb Muth 14:09Yeah, and a partnership, for sure, because without the feedback of the person you’re working with.understanding, like, we do this, and this happens to you, it’s very complicated as a practitioner to then be able to figure out, what do we do next? I see more and more clients these days, they come in and they just want to ask me within the first 5 minutes of, what am I changing? And I’m like, I have no clue yet. Like, you have to tell me what’s happened since the last time we did something, and then we have to look at labs, and we have to look at this, and we… it’s a synopsis.that we have to look at. You know, it’s not that black and white for us to be able to put the pieces together for them. Anju 14:47I think my most successful patients are the ones who are able to communicate with me.Their ups and downs. Yeah. And they also use their own intuition. Help me guide them. Dr. Deb Muth 15:06Yeah. Anju 15:07So, there are some people that they just hear, you do it, and you tell me.There are people who try to tell me everything. Dr. Deb Muth 15:15Okay. Anju 15:15Say, I want you to do this, do this, do this. Dr. Deb Muth 15:17Yeah, so I was like, okay. Anju 15:19I can do those things, but, you know, like. Dr. Deb Muth 15:21Yep. Anju 15:22think about blah blah. But, like, this… that collaboration.and, intuition. I kind of feel like even thoughI’ve trained allopathically as a traditional medical doctor. I feel like as I learn, I learn that being open and,Letting go of fear. Dr. Deb Muth 15:46Yeah. Anju 15:47And, not trying to jump on every, like, new thing, and being. Dr. Deb Muth 15:53consistent. Anju 15:54and diligent. really helps. Dr. Deb Muth 15:58It helps a ton. We see that, too, you know, the latest…Instagram influencer that’s talking about the latest topic, and all of a sudden, everybody sees themselves in there, and they must have that, but not realizing putting those connections together. It’s like when MTHFR came out, right? We were all so excited that this was going to be the detox gene.And then we learned so much more about genes, and now MTHFR is very popular again, and everyone’s talking about it, but they don’t understand how some of those other genetics fit together. And if you don’t understand that, we’ve all done it, we’ve all made people worse instead of better, sometimes when we’ve given too many methyl groups together, or this supplement without this support before we knew that there was another gene that we had to support for that.And I think it’s really important for people that are listening to us today talk about this, is don’t just jump on the bandwagon. Like, you really want to work with somebody seasoned who understands how all these pieces fit together. Anju 16:57Yeah, and I think that’s what individualized medicine is about.And there is no magic here, a magic bullet.I think that example of MTHFR is really good. Now, President Trump talked about Leukovorin. Dr. Deb Muth 17:14Yes. Anju 17:15in, and, you know, he’ll get up and say something like, leukovorin cures autism.And then the rest of us are like…Did you just say that? Dr. Deb Muth 17:26Yep, he did. Anju 17:30It’s folinic acid, it’s calcium folinic acid, it’s been around a long time. We’ve been using it for 20 years. Dr. Deb Muth 17:37Yeah. Anju 17:38But it does help a subset of people who potentially have what we call cerebral folate deficiency.And some of those people are misdiagnosed as autism. Dr. Deb Muth 17:50Yeah. Anju 17:51So, are you treating autism, or are you treating cerebral folate deficiency?same thing I could say about… I have a lot of cases of kids who recovered from autism.and severe ADHD using chelation type of. Dr. Deb Muth 18:06up. Anju 18:06Approaches, or detox approaches.again, did we treat their ADD and their autism, or did we treat their lead…Toxicity or lead burden, and their symptoms of those things got better. Dr. Deb Muth 18:20Yeah. Anju 18:20So, like, to put a big, like, a label like, oh, ADD on something, or autism on something, I think it does a disserviceTo the individuals, because it’s such a broad issue. Dr. Deb Muth 18:35It is, and I think the diagnosis has gotten to be much more popular these days.And yes, thank goodness we’re getting better diagnostics, but sometimes we’re getting over-diagnosis, or like you said, it may look like one thing, but it could be something else, but because it looks like autism, they’re going to get labeled with autism.And in some respects, that’s good, they can get more services that way, but sometimes we’re missing the actual picture of it. Can you talk a little bit about how autism is different than the cerebral folate deficiency? Anju 19:11Yeah, so there are some people that make an antibody to their folate receptor. Dr. Deb Muth 19:18Hmm. Anju 19:20So, to get folic acid into your cells, there’s a receptor on your cells. Dr. Deb Muth 19:25And then the folate has to bind to it, and then it lets it enter into the cells. Anju 19:30And there’s these receptors that allow folic acid to get into your brain.Now, you and I know when you put folate in your brain.On one end of the folate cycle, you help make more neurotransmitters. You’ll make something called BH4, and that’ll help make serotonin and dopamine, and then norepinephrine and epinephrine. So folate is really important for making your neurotransmitters, folate and B12.On the other end, it’s like, another cycle on the other end of folate is our methylation cycle.And methylation is so important for our RNA and our DNA, and making choline, phosphatoly choline, and making creatine for speech.And helping us with all the precursors for detoxification.So without folate in our brain, we can’t make our neurotransmitters efficiently, we can’t break them down efficiently, and we can’t detox our brain.Imagine what that will do to your brain. Dr. Deb Muth 20:36Yeah, Anju 20:37And you will see symptoms like speech delays, cognitive delays, processing issues, poor attention.All of those things. Excitation, anxiety.All of those, and so if the folate isn’t getting into the brain efficiently, then we’ll have all these symptoms, and we’ll end up with diagnoses like these. Dr. Deb Muth 20:59Yeah, so is there a way that people who are listening to this can request a test to see if they make this antibody to folate, or is it more of a diagnosis of exclusion? Anju 21:14That’s a great question. When I first started doing this, like, 20 years ago, there was, like, a university that was doing this.studies, and it was Dr. Quadros. He was the guy, and we would take samples and send them to his lab, and he would tell us about these blocking and binding. Dr. Deb Muth 21:30folate antibodies. Anju 21:32And if patients had positive blocking or binding folate antibodies, we would follow his protocol. And he’s done papers on patients with severe autism.Where he found these folate antibodies, and then did spinal taps on the kids, and they were associated with this cerebral folate deficiency. the cerebral… spinal fluid.And in his papers, he gave .5 to 2 milligrams per kilogram of calcium folinic acid, which is leukovorin. It’s a vitamin. And over a 6-month to a 12-month period.The majority of those patients improved drastically.Some of them regained speech, and some of them lost their autism diagnosis. Dr. Deb Muth 22:26Because they never truly had autism. Anju 22:29Well, they have autism symptoms, and that’s what autism is, but we call it autisms. Dr. Deb Muth 22:36Yeah. Anju 22:37And so now, like, we need the research to categorize these people. You know, what percentage of autism is cerebral folate deficiency? Yeah. What percentage of autism is, heavy metal. Dr. Deb Muth 22:51Bourbon. Anju 22:52And what percentage of autism is Clostridia overgrowth, or… Dr. Deb Muth 22:57Hmm. Anju 22:57microbiome… Dysfunction, and then there’s overlap. Dr. Deb Muth 23:01Right, yeah, Lyme and mold and viruses. Anju 23:04and infections, and you can see… Dr. Deb Muth 23:07injury from medications and things like that that happen, or birth traumas. Yeah, I mean, it’s not… it’s not as simple as what people think autism is.Why do you think that we’re seeing so much more autism today than when you and I were kids? We didn’t see this that often. I know environment has a lot to do with it, but do you have a couple of things that you suspect are contributing to the rise of autism these days? Anju 23:38Yeah, I mean, that’s a million dollar question. Dr. Deb Muth 23:40Right. Anju 23:41And, just because I work with children, you know it’s not just autism that’s epidemic, and yeah. Dr. Deb Muth 23:49You know that. I mean, it’s… it’s probably… if you add all the epidemics that are happening to children. Anju 23:54Autism still supersedes it.Now it’s 1 in 33s, 1 in 35 boys, I mean, it’s…children. It’s really sad. When I was in med school, it was 1 in 10,000. Dr. Deb Muth 24:10That’s crazy. Anju 24:11What’s causing it? I mean, obviously it’s multifactorial. Dr. Deb Muth 24:15Yeah, 80,000 chemicals in the environment that we never had before. Anju 24:20I, I, I, look, I’ve… 219 million. Dr. Deb Muth 24:26Oh my gosh. Anju 24:27I looked it up today. Dr. Deb Muth 24:29119 million different chemicals in the environment. Wow. Anju 24:33We don’t know how many of those are super toxic. Dr. Deb Muth 24:36Yeah, and we don’t know what they do together. Anju 24:38A lot of them were, like, before, like, grandfathered in and all of that.Yeah, it’s really crazy about the chemicals. So, chemicals… I kind of… feel like…you know, this burden of all this, it’s not just on our children, it’s on our mothers. Dr. Deb Muth 24:56Yes. Anju 24:56oh my gosh, the moms of these children that… And they don’t even realize it, you know, we’re just so happy to be pregnant and have a kid.So I think it really, really starts with that piece. Care, good prenatal care, yeah. Yeah, and not just what we think is prenatal care, taking your prenatal vitamins. Dr. Deb Muth 25:18Yes. Anju 25:19And going to your gynecologist, but what you and I think is prenatal care, you know, before you get pregnant, let’s detox, let’s clean up our diet, let’s get rid of those chemicals, let’s make sure we’re not in a moldy environment.You know, let’s do our due diligence, clean air, clean water, clean food, sunshine. When I did my residency at county, I don’t think I saw the sun for 3 years. Dr. Deb Muth 25:44How?Yeah. Anju 25:46it’s just that intense, and I was pregnant twice, and my eldest hasthe allergies and asthma. Number 2 is type 1 diabetes and mold sensitivities and allergies and asthma. Number 3 has severe chemical sensitivities, mast cell activation,Hormonal issues. Dr. Deb Muth 26:09Yeah. Anju 26:09And… number 4 is my… Golden, baby. Dr. Deb Muth 26:15And those three, you know, those years that you’re there, and you’re not seeing the sunlight, there’s vitamin D deficiency, and we don’t talk about vitamin D that much during pregnancy.I still am appalled that we’re giving folic acid these days during pregnancy instead of folate, but… Anju 26:36Folenic, or methylfolate? Dr. Deb Muth 26:38Yeah, nothing. So, when, when you,discovered vitamin D in pregnancy, and it’s linked to neurodevelopment outcomes. How did you stumble across that? Anju 26:50Well, in… when I started working on Copper Zinc, Dr. Walsh and I would go to the, like, DAN conferences.Yeah. At the time, and it was interesting, because DAM conferences were a collaboration between parents.And practitioners, and researchers. Dr. Deb Muth 27:10Very unique for. Anju 27:11That’s how that new IACC committee is. It’s a collaboration of parents. Dr. Deb Muth 27:17Hmm. Anju 27:18Practitioners, researchers, And individuals with autism. Dr. Deb Muth 27:25Yeah, so for those of you who are listening to us, it’s… we’re talking about the Interagency Autism Coordinating Committee that Bobby Kennedy just put together. It’s called IACC, and they are on a mission to try to do the research to figure out what’s causing autism. Anju 27:43Yeah, and not just causing it, like, these people have been living it, most of the people on that committee have been living it, and their whole lives, for some of them.And being able to bring forwardlike the question about vitamin D, we started seeing a lot of patients in Minnesota. Dr. Deb Muth 28:04Mmm. Anju 28:05who were from Somalia. Dr. Deb Muth 28:08Okay. Anju 28:09Who were… it was, like, 1 in 4 families with kids with autism.And the theory was that the vitamin D levels that they get in Somalia versus the vitamin D levels that the moms get in Minnesota. Dr. Deb Muth 28:27Hmm? Anju 28:28Affected the immune system. Dr. Deb Muth 28:31Yeah. Anju 28:32predispose them. So there’s a few papers on that. Dr. Deb Muth 28:36Yeah, that’s a… I mean, it would be a very significant difference, and when you’re thinking about genetically, like, what their culture, who they are as a species.was used to and adapted to with the sunlight and different things from a different region, geographical region, and then they moved to a new geographical region, that can take decades before the body adapts and readjusts.to that new environment. We don’t think about those things in…traditional medicine, and conventional medicine, as most people know it, but we do in functional medicine. Anju 29:14Yeah, so again, the clinicians were bringing this up, like, why am I seeing so many families? Dr. Deb Muth 29:18Yeah. Anju 29:18Then let me go to the… and then in the think tank, the vitamin D researcher said it’s vitamin D. Dr. Deb Muth 29:24Yeah. Anju 29:25And then they started researching it, and it was almost like a backwards… backwards. Dr. Deb Muth 29:31Thank you. You know, they didn’t first… Anju 29:33Think it. Dr. Deb Muth 29:34Think about it, yeah. Anju 29:35Until you start seeing… and that’s why I think that, like.clinicians like you and me, who are… I consider us on the front lines. We’re the front lines. We are seeing… we’re seeing this epidemic unfold. Dr. Deb Muth 29:46Yes. Anju 29:47front of our eyes, we’re seeing, like, the gut issues and the severe inflammation. We’re seeing the autoimmunity, and now they have to study it. Dr. Deb Muth 29:57Yeah. Anju 29:57They have to study this. They really, really, we really need, we really need protocols, we need tools, we need things that you and I have been figuring out anecdotally with our colleagues over the years, and, oh, how do we treat yeast? How do we treat Lyme? How do we treat metal burden?For this podcast today, I wanted to talk about low-level lead exposure, because for me.1 in 3 children have a lead level, above 5. 1 and 3. Dr. Deb Muth 30:31Yeah, that’s very high. Anju 30:33800 million children. Dr. Deb Muth 30:36And let’s clarify this, because the first thing people are going to think of is, what are they eating? They’re not eating lead paint to get this. That is not what’s happening here. They are getting lead from someplace else, and their bodies are not able to detox this. Anju 30:53And the reason I’m bringing this up is because when I was in residency at County in the 90s, I ran a… I worked at a lead clinic. Dr. Deb Muth 31:01And back then. Anju 31:03When we looked… we just diagnosed lead toxicity, the level was 60. Dr. Deb Muth 31:10Their level had to be 60 to diagnose them. Anju 31:13Correct. Dr. Deb Muth 31:13Oh my gosh. Anju 31:14And that’s when we would treat.And back then, there was a study, it’s called the TLC study, where they used DMSA, which is a drug to lower lead.And our goal was to get it from 60 to 20. Dr. Deb Muth 31:33And was the normal range the same back then as it is today? Anju 31:37The normal range has gone from 60 to 40 to 20 to 10 to 5 to 3.5.But you and I know I’m the normal range. Dr. Deb Muth 31:47Yes. Anju 31:47Zero. Dr. Deb Muth 31:48Zero. Anju 31:50So… so again, in my… in the lead clinic, we were given DMSA, and we got the lead from 60 to 20, and the number one thing was to get rid of the lead in the environment. Dr. Deb Muth 32:02Yeah. Anju 32:03But we haven’t evolved since then.Because in that study, It did not improve cognitive abilities. So if you think about what lead does, it causes attention issues, slow processing, it affects hearing, it can cause hyperactivity, it can cause impulsivity, it can cause aggression, it can cause constipation, it can cause hypotonia.So if you think about all these kids with ADD and autism, how many of them have low-level lead exposure from the lead pipes? In Chicago, it’s a big, a big problem. Dr. Deb Muth 32:37Yeah, Milwaukee. Anju 32:38Everybody thinks Flint, Michigan, but Flint, Michigan is not the only place. Dr. Deb Muth 32:42Right. Our infrastructure is so terrible, it has not been updated, and even though you might look in your house and you might see a white PVC or plastic pipe, what’s coming under the ground to the house in the cities is usually still lead. Anju 32:58Right. Right. Dr. Deb Muth 33:00Yeah. Anju 33:01So, I guess the point is, is that…the… the idea of, like, studying this. So, again, they study this, and they say, well, we’re not going to treat low-level lead exposure because it doesn’t improve their cognition.But did they really treat it? Dr. Deb Muth 33:18Right. We got it from 60… we got it from 60 to 20. Right. But when I know, where is the lead hiding? Anju 33:24So high. Look at the bones, it’s gonna be coming out. It’s gonna be coming out, especially during puberty. What happens to some of our kids during puberty? They just go a little wonky. Comes out again during menopause. Dr. Deb Muth 33:38Yes. Anju 33:39I don’t know, male menopause, too. Like, we’re all losing bone mass then, and our lead is coming out, our blood pressure goes up. So, again, these are some of the areas that I think, like, really need some… hard… looks. Dr. Deb Muth 33:53Right, yeah. So, what are you hopeful about this committee? Like, are you hopeful that this committee is going to be able to research some of these big things, and we’re really going to be able to find answers around some of the functional things and the biochemical things that we see, you and I know happen in the body, that might give some standardization and education to practitioners in the future. Anju 34:23Well, I think this committee understands the scope of the issues.And they’re coming from different perspectives, like I mentioned, research. Dr. Deb Muth 34:33Yeah. Anju 34:35really highly qualified MDs. MDs like you and me, who have been on the front lines. moms. Dr. Deb Muth 34:43Yeah. Anju 34:44dads, patience, And so, the strategy would be to get, again, their input, and then…get the places… people in places to do their research. And even make some guidelines and some, like, you know, thoughts about what we want to put out there. Dr. Deb Muth 35:05Yeah. Anju 35:05You know, how do we want to strategize for… Dr. Deb Muth 35:08Prevention. Anju 35:10Like, the pre-pregnancy thing. Dr. Deb Muth 35:12Yeah, I’m really hopeful that this doesn’t become a… political football,And it doesn’t get taken away if the administration changes or whatever, because people need to understand that this kind of researchthis is going to take decades for people to do. Granted, we have AI, and AI can help a little bit and get some things quicker.But trying to figure out all of these nuances to why the body does what it does is not gonna be, like, next week we’re gonna find out that this was the single cause, and I know a lot of people, they’re afraid of the vaccines, and that’s gonna be the sole answer.And that has a piece of it, but it is just a small piece of it for some people larger, but at the end of the day, that’s not what this is about. This isn’t about just labeling one thing that is the cause of autism, because it is not one thing. It is so multifactorial. Anju 36:09And I think that whole cause, I know,A lot of money has gone into. Dr. Deb Muth 36:16Yeah. Anju 36:16looking at that. They’re looking for the gene, right? The gene that causes it, and… Dr. Deb Muth 36:23answer. Anju 36:24They have not… they’ve spent millions of dollars looking for this.And it’s not gonna pan out. It’s not. Dr. Deb Muth 36:33I’m not. Anju 36:34pan out. It’s more complex, like we’re talking about. Dr. Deb Muth 36:38Yeah. Anju 36:38And, I do think that sometimes, you know.Even though, like, politically, it seems like it’s a political topic, but it has zero to do with politics. Dr. Deb Muth 36:52Yeah, exactly. This is our children. This is the future of our country, the world. I mean, America’s not the only place that has kids with autism. I mean, this is the future of humanity. If we don’t figure out what’s injuring our children, there will not be a humanity that you and I have seen. It will be different. And, and this is important, we owe it to the future of our generations, we owe it to our children to figure this out and clean up our environment, and make it safe for everybody. Anju 37:24Yeah. Clean up our air, clean up our water, clean up our food… Dr. Deb Muth 37:29Yeah. Anju 37:30You know, our lifestyle a little bit, but… Dr. Deb Muth 37:32hoodie? Anju 37:33It’s… it’s… it’s everywhere. I travel all over. Dr. Deb Muth 37:36Bye. Anju 37:37Consult with doctors in different countries, in Italy, in India, Bulgaria, Romania… Dr. Deb Muth 37:46Yeah. And. Anju 37:48we’re going to Australia for med maps to treat doctors in, in April. And it’s a problem everywhere. Dr. Deb Muth 38:00Yeah. Anju 38:01really big problem, and it affects everybody. Even if you don’t have a child with autism or a grandchild with autism, it’s still affecting families, becauseI kind of think of ADD as being on the spectrum, in the sense thatI think the same kind of positive issues that lead to the autism are causing the ADD, just to… you know, your genetics are playing a little bit of a different role, whatever… whatever protection you have is a bit more there, but we’re seeing kind of, like, similar metabolic… issues in our ADD population. Dr. Deb Muth 38:43Yeah. Yeah, there’s so many different levels of this, and it does affect everyone. Like, I think everybody knows… a family or someone in their classroom or their school or their community that’s affected by, definitely, ADHD, Asperger’s, autism, all of those things, whether you’re high functioning or not functioning or whatever.everything is affected. The school system is affected, your social circles are affected, your families are affected.the healthcare is affected. I mean, everything is affected. We owe it to our families and our communities to help people try to figure this out. Anju 39:22Yeah, and I think even if it’s not ADD, or ADHD, or autism we’re talking about, or even OCD, anxiety, depression, I mean, you know… Dr. Deb Muth 39:33Candace? Anju 39:34Any kind of chronic illness that people are dealing with has underpinnings of these kinds of, you know, issues. Dr. Deb Muth 39:43Yeah. Anju 39:44Any autoimmune issue? That’s great. Dr. Deb Muth 39:48inflammatory syndrome that we’re seeing these days, I mean, the pants-pandas piece, the biofilms, the strep, I mean, our environment is just so laden with infections and biofilms, and And, you know, when you and I first were learning about this, we never thought anything could cross the blood-brain barrier, right? It was pristine, there’s nothing getting in there unless you could drive it in there, and now we know that’s different, and now we’re seeing bugs in the brains of people who have had Alzheimer’s disease and dementia because they’ve donated their brains for research, and we can see what’s crossing the blood-brain barrier, and it’s really scary. Anju 40:24Yeah, yeah. There’s a lot of things we don’t know. Remember when we just found out that they… the brain had a lymphatic system? Dr. Deb Muth 40:33And that wasn’t About, what, 5, 6 years ago? 7 years ago, maybe? Yeah, not that long ago. Anju 40:38You’d be like, why wouldn’t the brain have a lymphatic system? Dr. Deb Muth 40:41Yeah! Yep. Anju 40:44Yeah, so things get in and out. Dr. Deb Muth 40:46They, they definitely. Anju 40:47You know, they get in easier than they get out, I think. Dr. Deb Muth 40:50I agree, I think they do, for sure, for sure. You know, when you’re talking to a family who’s undergoing issues like this, what’s the role, do you feel, in personalized nutrition to help them make things better? Anju 41:10I kind of go through, like, a little bit of a start here, start there, and then do this. I always start, number one, I say, okay, you gotta clean up your environment, because… We gotta do that. Dr. Deb Muth 41:24But that’s a… Anju 41:24process. And then number 2 for me is cleaning up the diet. And then, when you say personalized nutrition. To me, figuring out what is a good diet for the individual. Dr. Deb Muth 41:38Makes it a little bit difficult. Yeah. Anju 41:41I mean, there is, like, healthy eating concepts, where, you know, eat upside-down food pyramid kind of concept, I guess, is the new one, but whole foods, whole grains, organic as much as possible, especially for animal products, good fats, avoiding, you know, hydrogenated oils, and those seed oils, and… Just some basics, and then individualizing for my patients, a lot of people with any kind of autoimmune condition, and we kind of put autism in that neuroimmune, autoimmune, inflammatory That, gluten-free, dairy-free, and sugar-free kind of go there, like, as a given. If there’s a lot of gut issues, a lot of our folks have oxalate issues. And then we have to sometimes do low or limited oxalate diets. Many of my patients can’t convert glutamate to GABA efficiently. Dr. Deb Muth 42:44Yeah. So, high glutamates associated with OCD, and kind of looping or repetitive behaviors. Anju 42:51So, low-glutamate diets. And then some of my patients have SIBO, and then we do the low FODMAPs diet, and then some of my patients have messel, and we’ll do the fail-safe kind of concept with the fail-safe diet, so nutrition can get a little bit complex for certain people, but there are some basics, and then there are some, like, more of… Individual, kind of, diet approaches. And then there’s supplementation. There’s some things that I call foundational. For me, certain things most people need that have a chronic illness. Dr. Deb Muth 43:26Yeah. Anju 43:26Vitamin D3 is one of those. Omega-3s are another one for most. And then, because I did a lot of research on copper, zinc, I think 3 mineral… 4 minerals. I feel like people underdo minerals. They’re so important. Every single enzyme has a mineral cofactor, so… zinc is really important for my population with autism and ADD. 99% of them had high copper or low zinc in. Dr. Deb Muth 43:58Wow. Anju 43:59Over 400 patients that we tested. Dr. Deb Muth 44:01Wow. Anju 44:03And, magnesium.So, zinc, magnesium, and then the other two minerals I really like are selenium for glutathione. and molybdenum for sulfation, and glycolysis. So… So those are kind of my foundational pieces, and then I like to work on the gut next. So, from a nutritional perspective, prebiotics are my new favorite. Dr. Deb Muth 44:29Yeah, we go in and out with prebiotics, probiotics, postbiotics. Anju 44:34Yeah, exactly, symbiotics. Dr. Deb Muth 44:36Yes, exactly, exactly. Anju 44:38demos, and… Dr. Deb Muth 44:40Yeah. Anju 44:40So yeah, biofilm busting, and all of that, so… And then I go into my other nitty-gritty stuff, like you probably do. Dr. Deb Muth 44:47individualized, right? So, you created, True Healing Nature, a supplement line, a supplement company, correct? Anju 44:56Yeah, True Hing Naturals. Dr. Deb Muth 44:58Truly Naturals, okay. Anju 44:59True, he is hard. Dr. Deb Muth 45:01Oats! Anju 45:01True! Dr. Deb Muth 45:01Healing natural. Got it, sorry about that. Tell us a little bit about what made you decide to create a supplement company. Was it because you couldn’t find formulations that you wanted? Couldn’t find clean products? That’s a big problem for people, for sure. Anju 45:19Yeah, a little bit of both. I told you that my kids were really sensitive, they had a lot. Dr. Deb Muth 45:23I know. Anju 45:24And when I would even try to give them things like ibuprofen. Dr. Deb Muth 45:28or Benadryl. Anju 45:30For allergies, they couldn’t tolerate the products that were over-the-counter. Dr. Deb Muth 45:35Yeah. Anju 45:35So, in 2007, I opened a compounding pharmacy so I could make things clean for them. Dr. Deb Muth 45:42Yeah. Anju 45:43And I thought it was so valuable. And so then I started seeing, like, certain issues with my patient population, for instance, say, mitochondrial issues. So, I would compound a mito cocktail. in my pharmacy. And then I had True Healing Naturals manufacture it, so I didn’t have to have patients get it compounded. Dr. Deb Muth 46:08Got it. Anju 46:09So that particular product’s called Mito Rescue. Okay. But then, I started… I do a lot of oats testing. Organic acid urine tests. Dr. Deb Muth 46:19Yeah. Anju 46:20But there’s, like, a marker on there for, oxalates, and I saw a lot of patients with oxalates, and oxalates inhibit some… an enzyme called, pyruvate decarboxylase. And that basically means you can’t take your carbs and turn them into energy. Dr. Deb Muth 46:38Okay. Anju 46:39So, if I saw this pattern with high oxalates and high pyruvic acid, I knew that that enzyme wasn’t working very well, and that enzyme is B1, molybdenum, and biotin dependent. So, I started compounding doses of that. And then I turned that into a product called Motor Connect, because high doses of biotin help with connectivity in the cerebellum. Dr. Deb Muth 47:08Got it. So, I did come… kind of start with the compounding pharmacy, try it, use it, and then turn it into. Anju 47:17products, and I have one for copper-zinc imbalances called True Minerals. Dr. Deb Muth 47:21Yeah, to fix the problems that were not commercially available. Could you talk a little bit for people who don’t understand what a compounding pharmacy is? Anju 47:32So, when you guys go to a pharmacy, you, you know, you send a prescription, and it’s already, it’s manufactured, and you get it. Well, a compounding pharmacy actually makes that for you. So they get the raw ingredients, and then they make that prescription. So it’s still prescription-based. But, for instance, say, I want Nystatin. And I go to Walgreens or CVS, and the nystatin there is a liquid, and it has yellow dyes and sugar. Dr. Deb Muth 48:02Yep. Or it’s a title, and it’s red. Anju 48:04or it’s bread, and a tablet, and I, like, oh, I want to treat the yeast, but I don’t want to use this. So I sent my nystatin prescription to a compounding pharmacy, and it’s Nystatin. That’s what you got. Yep. Dr. Deb Muth 48:17disappear. Anju 48:18So, pure compounding pharmacy, it’s pure, it’s pure stuff. Especially for our mast cell people. They’re so sensitive, and, you know, my kids are all mast cell, and so I just find that excipients, some people will say, oh, this doesn’t work, and I said, it’s probably the excipient that’s stimulating your mast cell activation. So, yeah. So, compounding pharmacies, You know, with all the big, kind of. conglomerates and big companies, they’ve become… they used to be, like, mom-and-pop kind of places. And my pharmacy is like that. It’s just… it’s… it’s a few of us, and we… we do it, and it’s nothing big or fancy, but we get the job done. So, we compound things like methylcobalamin injections, hydroxycobalamin, low-dose naltrexone. Different things for chelation. So, it’s nice. I love having it. Dr. Deb Muth 49:11Yeah, the compounding pharmacies really have made a huge difference for people who are sensitive. You know, so many ingredients are contaminated with corn and gluten and soy and dairy and all the big things that we want to stay away from, especially if we’re trying to treat the immune system. And even if the manufacturer says that’s not in our product. it’s contaminated, usually, because they’re usually preparing it in a facility that has those things floating around. Right. And for people who are really sensitive, that’s going to create some issues. Anju 49:45Yeah, people who are sensitive are sensitive to parts per trillion. Dr. Deb Muth 49:48Yeah. Anju 49:49I found that with my daughter with chemical sensitivity. You don’t have to see it, or you don’t have to smell it, but they could react to it. Dr. Deb Muth 49:55Yeah. And, a lot of these, like. Anju 49:58These different, substances, for instance, like enzymes, even the natural enzymes. Dr. Deb Muth 50:03They’re cultured in Aspergillus. Anju 50:07And so they’re extracted from mold. Dr. Deb Muth 50:10Yeah. Anju 50:11And so the really mold-sensitive people will maybe take a digestive enzyme, and they’ll have a reaction, and they’ll not understand why. Yeah. But it’s not because of the enzyme, it’s because of where it’s coming from. Dr. Deb Muth 50:22Yeah, where it’s cultured from. And if you have mold toxicity and mold sensitivity, and we’re looking at your mold test, wondering why are you getting a hit while we’re trying to clear it out, sometimes we forget that those products, and a variety of products that we used are cultured from molds. Yeah. Anju 50:40Yeah, yeah. It’s hard for the laypeople to understand all. Dr. Deb Muth 50:45You know. Anju 50:45of these pieces, but I think that… It used to be, like, the insurance companies would cover prescriptions from compounding pharmacies, but over the years, the lobbying and all of that has gotten so intense where, you know, a lot of that ends up out of pocket, but it’s really… it doesn’t really get that much more expensive than a copay would be. Dr. Deb Muth 51:05Right, right. Anju 51:06People just don’t know about it, yeah. Dr. Deb Muth 51:08Yeah, absolutely. So, you’ve been doing this now for more than 17 years, and you’ve made some remarkable progress with your patients. Can you share some success stories that still inspire you to do what you do every day? Anju 51:27I don’t know about you, but, like, when you first start, I think, God puts you… God puts all those really gray cases in front of you, because you’re like, whoa! Dr. Deb Muth 51:37Yes, and maybe… Anju 51:38I gave this patient methylcobalamin, and they started talking. Yeah. So methyl B12 back in the day was huge. you know, Dr. Nebrander’s protocol, and we would use that, and we would get speech, and… I mean, I’ve… it’s just… there’s hundreds of cases. There’s hundreds of cases, and same with Leukovorin now. Not for everybody, but when it really works, it’s really, really decent. Dr. Deb Muth 52:07Yeah, and worth a try, you know, if… if we suspect that’s what’s going on, these things are worth a try, because sometimes you just never know what’s going to be the key that unlocks the answer for them. Anju 52:19Yeah, but I think, you know, like, I can say… chelation, or… you know, I can, like, throw out a bunch of stuff. Dr. Deb Muth 52:26Okay. Anju 52:27In terms of, like, I’ve… I… I have those families, and I have those kids who are just… they’re just amazing, and they’re in college, and having jobs, and having kids, and… Dr. Deb Muth 52:38Yeah. Anju 52:38you know, all of that, but I think, you know, the ones that really strike me are the ones that I have to work really hard to get. Dr. Deb Muth 52:44And then we’. Anju 52:45they go, it’s not like, oh, I just did the diet, I’m cured, or I did this, and I’m better, or… Right. And I have those cases where the parents come to me and they say, I never thought my kid would Be going to college. And I never thought we would be here. So, those are the ones that really, like, when I get the little notes, or the, like, the college or the high school graduation pictures, and they… and some of them, you know, you lose touch with because they don’t need me anymore. Dr. Deb Muth 53:19Yeah. Anju 53:20And then you hear about it later. And then, I think the ones that don’t get better are the ones that, like, sit with me the most They just sit with me, and we’ve had this population of children with severe apraxia. So, apraxia is a motor planning issue, but if you saw these patients, you would think that they were… mentally deficient. Dr. Deb Muth 53:44Hmm. Anju 53:45Because they can’t talk. Dr. Deb Muth 53:46Yeah. Anju 53:47They’re the classic person that you would see that looks autistic. You know, running around, excited, verbal stimming, no speech. Dr. Deb Muth 53:57Hmm. Anju 53:58And that group of patients are incredibly Brilliant. And we are just finding out about how smart they are. There’s a book called Underestimated by J.B. Hanley and his son Jamie. JV has all the resources in the world. He used to put those ads in the New York Times about autism and vaccines. He could take his kid anywhere and do any treatment, and still, we… Blocked. Locked. Couldn’t get through. Couldn’t get through. And they started, spelling. To communicate, and this speller’s method, and it just opened a door. And it opened a door for so many of my patients who are metabolically challenged, so we do help them metabolically. Getting that ability to communicate. Some of them never got high school diplomas, and they went back to get their high school diplomas so they could go to college. Dr. Deb Muth 54:56Oh, wow, that’s amazing stories. Anju 54:59Yeah, and Elizabeth Bonker is one of those spellers, and she… she was a valedictorian in her high school, college. And she did a valedictorian speech that went. Viral, and she’s one of the people on that committee. Dr. Deb Muth 55:13That’s awesome. Anju 55:14He’s non-speaking. She… she can’t not speak. Dr. Deb Muth 55:20Wow. Anju 55:21But they asked her to be on this committee. Dr. Deb Muth 55:24That’s fantastic. Anju 55:26Huge. Dr. Deb Muth 55:27That’s huge. It is huge. There’s a way she can communicate, she just can’t verbalize the way you and I verbalize. Anju 55:34She’s brilliant. I mean, people on that committee, the, the individuals with autism on that committee, I know they’re brilliant people. Wow. But if you… if… If people saw them, they wouldn’t see that. Dr. Deb Muth 55:47Right. Anju 55:47So, I guess, for me, it’s like seeing the brilliance, seeing the competence in individuals, and as a practitioner, just trying to optimize it. But I know, like, the neurodiversity people say, okay, you know. We’re fine, and it’s like, yes, you are fine, you’re fine, and it’s okay. Whatever it is, it’s okay. But if you’re struggling metabolically, and we can help you feel better. What’s… what’s the harm in that? Dr. Deb Muth 56:13Right, let’s do that. Yeah. So you’re also part of something called MAPS, and you’re educating doctors worldwide. Tell us a little bit about MAPS, and how do you see the integrative pediatrics evolving in the next decade as a result of what we’re learning today? Anju 56:36I think we’re at a crossroads, and Maps is kind of in the middle of that crossroads. It used to be called Dan. Dr. Deb Muth 56:47Okay. Anju 56:47Autism Now. Dr. Deb Muth 56:48Yeah. Anju 56:49And then they kind of dissolved Dan and turned it into MedMaps. And MedMaps is Medical Academy for Pediatrics and Special Needs. So it’s not just special needs, it’s pediatrics. as well.So it’s kind of like the functional medicine for peds. And our goal is to train an army of clinicians to be the frontline. And how medicine should be, and how people should be trained. We should train them to do these types of things from the beginning. Because now it’s backwards. Dr. Deb Muth 57:28Right. Anju 57:30they come see us when nobody else can help them. But, so, we have some good leadership, and then… We are just trying to get people trained so that they understand that this is the future. Dr. Deb Muth 57:50If there’s a practitioner that’s listening to this, how do they get involved in MAPS? Anju 57:55They could come to a conference. Dr. Deb Muth 57:57Okay. Anju 57:58And the website is medmaps.org. And there’s 2 conferences a year. And we have scholarships, and we want people to come, so contact You know, the executive director, and… We just want people to come, share… their experiences, learn about functional medicine, it’s evidence-based, we try to… it’s really scientific, you know, we talk a lot of science. Dr. Deb Muth 58:25Oh yeah, a lot of science. Anju 58:26We talk a lot of science, and and so hopefully we can move all of this forward. Baster. Dr. Deb Muth 58:35I think the greatest thing, when you get into the functional medicine integrative space like this, and MAPS, and some of the other environmental academies and things like that. A lot of people might think it’s not science-based, and I’m always amazed at how much science we have, and it’s right, it’s all the things that you and I learned in biochem class, and chem class, and organic chem, and we were like, oh, let’s just learn this to be done with it. And then you get back, and you start doing integrated medicine, and you realize, like, all of that biochemistry stuff is what we needed to truly understand to fix people these These days, and you go back and you have to learn that in an intense version of it. Anju 59:18I felt like I finally understood the Krebs cycle, when I learned how it made metabolic stents, instead of just memorizing these cycles for… For the… Dr. Deb Muth 59:30Right? Like, they, like. Anju 59:32They just make sense to me. Dr. Deb Muth 59:34Yeah. Anju 59:35And I think that’s so important to understand, that all of this has science behind it, and it’s there, and the research is there. Dr. Deb Muth 59:46It’s just us having to learn how to utilize it, and recognize that not every person is going to be straightforward, and what we do for one might not work for another. There’s… It’s not as easy as prescribing a prescription and letting the person walk out the door in 10 minutes. That’s not what this is about at all. Anju 01:00:05No, and at MedMaps as well, they have a call for abstracts, and so we’re always looking for research, experience, so if any of the clinicians out there have, you know, things they want to share. then send an abstract to Maps. What a great blonde. I think, one of my doctor friends is doing an abstract on research that was done on sensory qigong massage. Dr. Deb Muth 01:00:34Oh. Anju 01:00:34And it helped with speech, and the theory was that, we were all thinking of the sensory system in the brain, the sensory system. In the periphery being affected neurologically, and how to turn that back on. So, it was… it’s… Dr. Deb Muth 01:00:51That’s neat. Anju 01:00:51Again, with the research, and with the science behind it, and with, like, clinical trials, and all of that. Dr. Deb Muth 01:00:58That’s awesome, I love that.For parents that are just starting in this journey, what would you recommend be their first one or two steps? Anju 01:01:10Educate, educate, educate? How do you get educated? I do think that, TakaNow.org is a good place for, like, a biomedical approach, or this functional approach for autism. It’s the Autism Community in Action. MedMaps is doing a parent conference in March. Dr. Deb Muth 01:01:31Oh, awesome. They usually do that around, Memorial Day, right? Anju 01:01:36They’ll do it around Labor Day in September. Dr. Deb Muth01:01:40Labor Day in September, okay. Anju 01:01:42Yeah, and then mid-March. Dr. Deb Muth 01:01:44Okay. Anju 01:01:45Yeah. And they hadn’t done a parent conference before, but we had parents that wanted to come to the conferences, and it was just for clinicians before. Dr. Deb Muth 01:01:54Got it. Is it Autism One that does theirs around Memorial Day? Anju 01:01:59Oh yeah, they don’t exist anymore. Dr. Deb Muth 01:02:01Don’t, really. Anju 01:02:03conferences. There was. Dr. Deb Muth 01:02:06NAA, the National Autism Association. Anju 01:02:09They don’t do a lot of parent conferences in functional medicine either, so there’s a few left. Documenting Hope. That’s another really nice one. Oh, that’s great. Dr. Deb Muth 01:02:21So, what last words do you want to leave with our listeners? Anju 01:02:29You know, that’s… people always ask that at the end of these… I, I do feel that, Listen to your heart, you know, follow your intuition. Dr. Deb Muth 01:02:40I’ll let that guide you. Anju 01:02:42There’s a lot of information, sometimes it gets to be too much information. It’s hard to process everything, try not to make impulsive decisions about things. And… If you have a child with special needs, or if you have a grandchild with, issues. Presume competence. There’s a lot there. Dr. Deb Muth 01:03:04Yeah. Anju 01:03:05Especially some of these kids with behavior issues. I don’t know how many patients of mine are… Put on psychotropic meds. Metabolic issues, and, you know… It’s like, a lot of them have pain, like headache, abdominal pain, and inflammation, and they’re treating them with psych meds. Dr. Deb Muth 01:03:25Yeah. That’s sad, isn’t it? Anju 01:03:28I think, you know, try to look for the underlying cause. Not just band-aid things. Dr. Deb Muth 01:03:34Where can listeners, learn more about your work and what you do? Anju 01:03:40Oh, that’s tough. I don’t have a book. One of these days. Dr. Deb Muth 01:03:48Yes! Anju 01:03:49Yes, one of these days. I think, you know, med maps, we have a… if they’re clinicians. Dr. Deb Muth 01:03:55Hmm? Anju 01:03:56I have lectured a lot. For, for, communities like Taka, so there’s just a lot of… lectures that I’ve given online. Dr. Deb Muth 01:04:09Awesome. Well, thank you for taking your time with us today. It’s been a great conversation with you. Anju 01:04:15Thank you so much for inviting me, Debra. I’m honored to be here, and thank you for doing the work that you do to put Put this out there for people, because it’s really important information. Dr. Deb Muth 01:04:27Thank you. Thank you for joining me today on Let’s Talk Wellness Now. Today’s discussion with Dr. Usman reminds us that there’s always more we can do. We can look deeper into biology, environment, and lifestyle. to heal the next generation. If this episode inspired you, please share it with a parent or a practitioner who believes every child deserves a chance to thrive. And to learn more about Dr. Usman, you can visit TrueHealthMedical.com or TrueHealingnaturals.com. And if you’re ready to explore your own root cause healing, visit us at Serenityhealthcarecenter.com. You can also follow me on Instagram, and don’t forget to subscribe so you never miss an episode of Let’s Talk Wellness now. Until next time. I’m Dr. Deb, reminding you to nurture your body, mind, and spirit. Be well, and I’ll see you soon.The post Episode 262 – The Root Cause of ADHD & Autism: Beyond the Diagnosis with Dr. Anju Usman Singh first appeared on Let's Talk Wellness Now.

L'IA rebat les cartes. Et elle le fait vite. Tellement vite qu'on court tous un peu dans tous les sens, poussés par l'excitation ou, plus souvent, par la peur.Mais courir sans direction, c'est exactement ce qu'on fait quand on laisse nos émotions prendre le volant.Dans cet épisode solo, je partage une approche pour reprendre le contrôle : raisonner par premiers principes.Plutôt que de réagir impulsivement à chaque nouvelle disruption, je vous propose de revenir à ce qui est fondamental pour vous, pour votre équipe, pour votre entreprise. Et de construire à partir de là.————— CHAPITRAGE —————(00:00) Intro + update sur la refonte du podcast(02:15) Retour sur le AI Product Day et le constat troublant(04:08) L'IA : une révolution subie, pas choisie(08:47) Pourquoi on court comme une poule sans tête(11:47) Excitation et peur : les deux émotions qui nous animent(13:14) Comprendre le rôle des émotions avec les neurosciences(15:31) L'excitation face à l'IA : un monde d'opportunités(16:20) La peur face à l'IA : quand l'écart se réduit(17:14) L'incertitude génère la peur, et la peur paralyse(19:26) Approche impulsive vs approche intentionnelle(21:35) Introduction au concept de premier principe (First Principles)(22:41) Raisonnement par analogie vs raisonnement par premier principe(23:07) Framework pour appliquer le raisonnement par premier principe(24:32) Exemple personnel : ma décision de me lancer dans le coaching(28:02) Contre-exemple : l'entreprise sans vision qui s'éparpille(29:05) Comment appliquer ce raisonnement face à l'IA(30:33) En tant qu'individu : revenir à ses valeurs et son pourquoi(31:20) Récap et conclusion————— RESSOURCES —————Paul Valéry (auteur mentionné)Concept des First Principles (Aristote)AI Product Day (conférence)————— 5 ÉTOILES —————Si cet épisode vous a plu, pensez à laisser une note et un commentaire sur Spotify ou Apple Podcast. Ça ne vous coûte rien et ça m'aide beaucoup !————— COACHING —————Vous êtes leader tech ou product face à des défis majeurs ?

In spiritual circles it's very trendy to speak of “raising frequency” or accessing “higher vibrations,” but what if higher vibration isn't mystical at all, but a precise description of physics at work?In this episode, Thom explores how order, coherence, and peace naturally emerge when we reduce excitation, rather than seek to raise it.Drawing on the laws of thermodynamics, Thom demystifies the subject and explains the fundamentals of sustainable change.Episode Highlights[00:45] Q – What Is “Higher Vibration”?[01:16] A – Excitation and Thermodynamics[03:46] Why You Can't Force Peace[06:29] Superfluid Helium Seeks Unboundedness[08:45] Superconductivity in Simple Terms[10:05] Meditation and Society[13:41] The Meissner EffectYou can also watch this episode on YouTube here: https://youtu.be/8KUIB4PlifkUseful Linksinfo@thomknoles.com  https://thomknoles.com/https://www.instagram.com/thethomknoleshttps://www.facebook.com/thethomknoleshttps://www.youtube.com/c/thomknoleshttps://thomknoles.com/ask-thom-anything/ Registration is now open for Thom's only rounding retreat for 2026, in Sedona from May 21-25.This is your one and only opportunity this year for deep rest, stress release and consciousness expansion through industrial-strength meditation, along with twice-daily knowledge sessions with Thom.You'll enjoy delicious retreat-friendly meals and the beauty and healing powers of the Red Rocks of Sedona. Register before February 28th and you'll save $500 on your retreat fee. You can find out more at thomknoles.com/sedona.

Video Link: https://www.youtube.com/watch?v=FA1QdeuGhJEIn this whiteboard-style episode, we dive deep into the auditory brainstem response (ABR) and its profound implications for the autistic phenotype, tracing sound from the cochlea's powerful endocochlear potential through multi-step brainstem relays to the thalamus and auditory cortex. Highlighting high excitation paired with low inhibition, we map how poor filtering at key stations—like the superior olivary complex, lemniscus, and inferior colliculus—leads to listening dissonance, where sounds blend uncontrollably into overwhelming noise. The discussion underscores the mesencephalon's critical role in sensory gating, binaural processing, and the tragic risks of overload, emphasizing why compromised inhibition cascades into sensory chaos and the urgent need for understanding these upstream mechanisms.Daylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 auditory processing episode: low inhibition + high excitation = sensory overload; mesencephalon key for hearing, vision, motor in autism00:55 ABR & Mesencephalon Focus Review prior ABR episode (wave 5 emphasis); mesencephalon central for toxicity phenotype sensory issues01:17 Brainstem Anatomy Slices Sliced brainstem views: medulla, pons (football shape), small mesencephalon, thalamus/subcortical above02:17 Hearing vs. Vision Pathways Hearing multi-step (cochlea → brainstem → thalamus); vision faster (retina → lateral geniculate/superior colliculus)03:21 Cochlea & Endocochlear Potential Spiral cochlea powers hearing; highest DC voltage (endocochlear potential ~+85-100mV) via potassium gradient; melanin underrated07:56 ABR Waves 2-7 Breakdown Wave 2: exiting cochlea; 3: cochlear nuclei sync; 3-4: superior olivary/lemniscus (ITD/ILD binaural, glycine/GABA inhibition); 5: inferior colliculus; 6-7: medial geniculate to A1 cortex14:17 Inferior Colliculus Role Glutamatergic excitation; binaural convergence; gamma needed for suppression (challenging in autism)17:01 Thalamus Entry & TRN Gating Wave 6: subcortical/thalamus; TRN (GABA sectors) filters sensory; compromised in autism risks overload23:20 Listening Dissonance Intro Sounds blending issue in autism; starts at olivary/lemniscus due to poor inhibition; firehose-like overload35:59 Signal-to-Noise & Prefrontal Effort High excitation/low inhibition = noise dominance; recruits medial prefrontal/ACC/insula for top-down control40:50 Overwhelm Consequences Hijacked emotional circuits (amygdala, insula); leads to shutdown/elopement; avoid talking when overwhelmed.X: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Starting with von Békésy's traveling wave and the cochlea's +80 mV biological battery, we move millisecond-by-millisecond through the auditory brainstem response (ABR Waves I–V), auditory nerve, cochlear nucleus, superior olivary complex, inferior colliculus, thalamic reticular nucleus, and finally primary auditory cortex (A1). The Endocochlear Potential (EP) is the highest DC voltage in the human body. As signals travel, excitation-inhibition attempts to balance that. When intact, brains can filter noise and locate meaningful sound. In Autism, reduced GABAergic sculpting (parvalbumin, somatostatin, and VIP interneuron dysfunction) plus lower myelination and a delayed Wave V — already detectable on the newborn hearing screen — turn ordinary environments into an unfiltered flood. The result is listening dissonance: a moment-to-moment perceptual struggle that collapses 40-Hz gamma, recruits massive frontal effort and emotional regions of the brain, frequently ends in sensory overload, shutdown, or literal pain. We close with the exact equation the pathway reveals: Low Inhibition + High Excitation = Sensory Overload.Daylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com0:00 Chroma Light Devices and Daylight Computer Company01:56 Audition & Autism; von Békésy Traveling Wave & Tonotopy; Hair Cells & Cochlear Amplifier04:20 Endocochlear Potential (+80 mV Battery); Bioelectric Currents06:30 Stria Vascularis, Melanin, & Water Role08:15 Auditory Nerve – ABR Wave I (1.6 ms)08:36 ABR Wave II (2.7 ms)09:00 Cochlear Nucleus & Early E:I12:10 ABR Wave III – Superior Olivary Complex (3.8 ms)12:13 Binaural Processing & Calyx of Held15:00 ABR Wave V – Inferior Colliculus (5.6 ms)15:42 Inferior Colliculus Gamma & Cell Types18:00 Thalamus MGN & TRN Noise-Canceling21:30 2021 Newborn ABR Study – Prolonged Wave V Biomarker24:30 Listening Dissonance Explained28:30 Auditory Cortex Gamma Collapse in Autism32:30 Primary Auditory Cortex A1 Mini-Columns36:00 Parvalbumin, Somatostatin & VIP Interneurons39:00 Formula: Low GABA + High Excitation = Overload & PainX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Jérôme Rothen se chauffe contre un autre consultant, un éditorialiste ou un acteur du foot.

Depuis un peu plus d'un siècle elle rythme la vie des élèves, professeurs et parents. Entre angoisse et excitation, réformes et autres rayons bondés dans les supermarchés, une petite rétrospective de la rentrée des classes est de mise en ce début du mois de septembre. Une séquence réalisée par Lucile Poulain Sujets traités : Classe, rentrée, école, élèves, professeurs ,parents. angoisse ,excitation, réformes Merci pour votre écoute Un Jour dans l'Histoire, c'est également en direct tous les jours de la semaine de 13h15 à 14h30 sur www.rtbf.be/lapremiere Retrouvez tous les épisodes d'Un Jour dans l'Histoire sur notre plateforme Auvio.be :https://auvio.rtbf.be/emission/5936 Intéressés par l'histoire ? Vous pourriez également aimer nos autres podcasts : L'Histoire Continue: https://audmns.com/kSbpELwL'heure H : https://audmns.com/YagLLiKEt sa version à écouter en famille : La Mini Heure H https://audmns.com/YagLLiKAinsi que nos séries historiques :Chili, le Pays de mes Histoires : https://audmns.com/XHbnevhD-Day : https://audmns.com/JWRdPYIJoséphine Baker : https://audmns.com/wCfhoEwLa folle histoire de l'aviation : https://audmns.com/xAWjyWCLes Jeux Olympiques, l'étonnant miroir de notre Histoire : https://audmns.com/ZEIihzZMarguerite, la Voix d'une Résistante : https://audmns.com/zFDehnENapoléon, le crépuscule de l'Aigle : https://audmns.com/DcdnIUnUn Jour dans le Sport : https://audmns.com/xXlkHMHSous le sable des Pyramides : https://audmns.com/rXfVppvN'oubliez pas de vous y abonner pour ne rien manquer.Et si vous avez apprécié ce podcast, n'hésitez pas à nous donner des étoiles ou des commentaires, cela nous aide à le faire connaître plus largement. Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

Dans cet épisode de 3 minutes Prépa Physique, (re)découvrez le couplage excitation contraction... en seulement 3 minutes !Si vous souhaitez aller plus loin, voici une ressource complémentaire : Le cri peut impacter vos performances↳ Tous les lundis à 8h, je vous livre les notions essentielles de la préparation physique issues de mon expérience de vingt ans dans le haut niveau en 3 minutes top chrono !

Dans cet épisode du Son du Désir, Eve invite sa complice Liza à partager une après-midi intime pleine de baisers, de caresses et de massages sensuels. Très vite, la tendresse laisse place au désir, et les corps s'abandonnent à une expérience érotique à trois, où le plaisir se découvre sans tabou. Plongez dans une histoire charnelle, immersive et excitante, pensée pour éveiller vos fantasmes et stimuler vos sens. Abonnez-vous dès maintenant et laissez votre imagination s'envoler ! Devenez VIP pour écouter des centaines d'audios sexe romantique sur www.lesondudesir.frHébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Invités : - Danielle Gilbert, animatrice  - Gauthier le Bret, journaliste - Dominique Grimaud, musicien - Sophie Obadia, avocat - Stéphane Clerget, pédopsychiatre Vous voulez réagir ? Appelez-le 01.80.20.39.21 (numéro non surtaxé) ou rendez-vous sur les réseaux sociaux d'Europe 1 pour livrer votre opinion et débattre sur grandes thématiques développées dans l'émission du jour.Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

J'avais bien souvent essayé d'imaginer quelles pourraient être mes sensations, ou mes émotions si je devais la voir se faire prendre par un autre homme sous mes yeux. Nous en avions même fait des jeux de rôle, mais il n'avait jamais été question de les concrétiser. Récit original par Olivier. Voix par Supernova (https://www.deferlante.be/vers-le-plaisir/)

Elle avait soigneusement choisi la petite culotte en soie, couleur chair, fine et invisible sous la robe en lin. Mais par ces chaleurs insupportables, la culotte brésilienne était franchement de trop. Rien qu'une envie: quitter la réunion, aller aux toilettes et l'enlever. Une fois là-bas, ne pas résister à la tentation: passer ses doigts sur la moiteur. Apprécier le glissement des doigts, tout en tendresse, tout en finesse... Récit original par Elodie Voix par Supernova (https://www.deferlante.be/vers-le-plaisir/)

À l'époque, je flirtais avec une collègue via messagerie. Rien à voir avec les systèmes actuels, oh non. C'était plus lent, moins direct, le jeu était d'autant plus excitant. On échangeait des messages ambigus, provocants, jusqu'au jour où je lui ai lancé un défi... Récit original par Alain Voix par Supernova (https://www.deferlante.be/)

Alors, ce matin, on va enregistrer un nouvel épisode. Cette fois-ci, on ne va pas chez quelqu'un. On va dans un ministère. Eh oui ! Quand on va à la rencontre d'une personnalité politique, il y a toujours un mélange d'excitation et de méfiance. Excitation parce qu'on va parler à quelqu'un qui détient une part du pouvoir, dont les mots et les décisions peuvent changer des choses. Méfiance parce que la parole politique est toujours à prendre un peu avec des pincettes. Aurore Bergé est ministre chargée de l'égalité entre les femmes et les hommes et de la lutte contre les discriminations. C'est elle qui a demandé à nous rencontrer. Un rapport sur la ménopause rédigé par la députée Stéphanie Rist, très engagée sur le sujet, vient tout juste d'être publié. Et Aurores Berger veut en parler à notre micro. Alors bien sûr, je ne suis pas là pour faire de la complaisance, mais si la parole politique s'empare enfin de ce sujet invisible, il faut l'entendre. Et après, chacun se fera son avis, moi la première.Bon épisode !La ménopause en France : 25 propositions pour enfin trouver le chemin de l'actionINFORMATION SUR LA MÉNOPAUSEMieux informer les femmes sur les symptômes de la ménopause en mobilisant les moyens publics disponibles.Promouvoir une vision positive et non anxiogène de la ménopause, en luttant contre les stéréotypes.Intégrer l'information sur les phases hormonales dès le collège, y compris le vieillissement.Commander à Santé Publique France une campagne d'information grand public sur la ménopause.Utiliser les réseaux sociaux et le numérique pour diffuser une information fiable sur la ménopause.Définir un cadre de financement pérenne pour l'information/prévention via les ARS.Proposer au Planning Familial d'étendre ses compétences à l'accompagnement de la ménopause.PRISE EN CHARGE SANITAIREActualiser les recommandations HAS sur la ménopause d'ici fin 2025 avec une approche globale.Renforcer la formation initiale et continue des professionnels de santé sur la ménopause.Compléter le questionnaire "Mon bilan prévention 45-50 ans" pour détecter les symptômes.Inscrire dans la convention médicale une consultation longue de début de ménopause.Créer un parcours individualisé et pluridisciplinaire de la ménopause (PIM) pour chaque femme.Intégrer la ménopause dans la démarche Handigynéco pour une meilleure accessibilité aux soins.Organiser des Assises de la Ménopause pour construire une Stratégie Nationale.Soutenir la recherche fondamentale et innovante sur la ménopause.CONDITIONS DE TRAVAILSensibiliser les entreprises au coût économique de la ménopause en France.Intégrer la ménopause dans le Plan Santé au Travail n°5 (PST 5).Produire des statistiques santé/travail selon le sexe et la tranche d'âge. Créer un guide « Ménopause au travail » à destination des managers et salarié·e·s.Intégrer la ménopause dans les politiques RH et managériales des grandes structures.Sensibiliser les agents de France Travail aux risques de désinsertion professionnelle.Adapter les équipements de bureau selon les recommandations du GEMVI contre la sédentarité.Encourager chaque entreprise à établir un diagnostic et un plan d'adaptation des postes.Intégrer la ménopause dans la visite médicale de mi-carrière à 45 ans.Créer un cadre juridique pour expérimenter un congé ménopause dans les collectivités publiques.Distribué par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

Aujourd'hui, Barbara Lefebvre, Jean-Loup Bonnamy et Fatima Aït-Bounoua débattent de l'actualité autour d'Alain Marschall et Olivier Truchot.

On l'avait quitté avec un record personnel à Tokyo. Mais l'euphorie a désormais laissé place à des doutes pour Dorian Louvet, dans son projet de réussir les 7 marathons majeurs avec un chrono dantesque. En panne physique, Dorian tente de retrouver la forme... Alors que le marathon de Boston arrive dans 11 jours (21 avril), suivi moins d'une semaine après par le marathon de Londres (27 avril). Comment gère-t-il sa prépa sans les jambes ? Garde-t-il le moral ? L'excitation va-t-elle le booster ? Comment va-t-il gérer l'enchainement de 2 marathons en 6 jours ? Dorian Louvet dit tout à Benoit Boutron et Yohan Durand. 

Check out our recap and breakdown of Season 4 Episode 8 of the Big Bang Theory! We found 7 IQ Points!00:00:00 - Intro, emails, trial update, birthday gift unwrapping00:26:28 - Recap Begins00:26:54 - Whip Classes00:35:30 - Extra 21 Seconds of Raiders of the Lost Ark 00:42:54 - Star Trek Nemesis - Error00:49:04 - Nail Fungus from Mani/Pedi01:04:07 - Bovine Spongiform Encephalopathy - Error01:08:12 - The Miller's Tale01:14:13 - A brief history of the SockFind us everywhere at: https://linktr.ee/theoreticalnonsense~~*CLICK THE LINK TO SEE OUR IQ POINT HISTORY TOO! *~~-------------------------------------------------Welcome to Theoretical Nonsense! If you're looking for a Big Bang Theory rewatch podcast blended with How Stuff Works, this is the podcast for you!  Hang out with Rob and Ryan where they watch each episode of The Big Bang Theory and break it down scene by scene, and fact by fact, and no spoilers! Ever wonder if the random information Sheldon says is true? We do the research and find out! Is curry a natural laxative, what's the story behind going postal, are fish night lights real? Watch the show with us every other week and join in on the discussion! Email us at theoreticalnonsensepod@gmail.com and we'll read your letter to us on the show! Even if it's bad! :) Music by Alex Grohl. Find official podcast on Apple and Spotify https://podcasts.apple.com/us/podcast/theoretical-nonsense-the-big-bang-theory-watch-a/id1623079414

Exoplanets, sure. Exo-moons too, apparently. But exo ... comets?! Yes indeed, they're a real thing, and we've known about them for ages! How do you spot something so tiny around another star, so far away? Emily has the insider knowledge, because it's something she's genuinely investigating in her job as an actual, real-life astronomer.On the web: syzygy.fmHelp us make Syzygy even better! Tell your friends and give us a review, or show your support on Patreon: patreon.com/syzygypodSyzygy is produced by Chris Stewart and co-hosted by Dr Emily Brunsden from the Department of Physics at the University of York.Some of the things we talk about in this episode:• Comets: dirty snowballs• Exocomets• Famous comets• Shoemaker-Levy's Jovian rendezvous• Beta Pictoris, HyperMegaMall of astrophysics• Exocomets around Beta Pic• TESS, everyone's favourite exo-hunter

In this video, I'll be sharing the most effective way I've found to work with perimenopausal symptoms using herbs and understanding your unique energetic constitution or tissue state. As a clinical herbalist, I believe that finding the right match can make all the difference. I'll introduce you to American Ginseng (Panax quinquefolius)—an herb every woman entering perimenopause should consider for overall vitality, along with specific dosing tips. Plus, I'll dive into the four most common tissue states that often get out of balance during this stage: Excitation, Depression, Tension, and Atrophy. I'll guide you through how to identify these states in your body and share the best herbs to help restore balance, with dosing recommendations for each. I'll also cover commonly used herbs like Black Cohosh, Hops, and Dong Quai, explaining which specific patterns they work best with and how they can support your journey through perimenopause. I keep things lighthearted and easy to understand, so you can quickly discover the herbs that will help you feel more at ease and vibrant through this transition. Product Links: Herb for All Women - American Ginseng - Panax quinquefolius - https://mountainroseherbs.com/american-ginseng-extract For Hot/Excitation Types  Milky Oat Tops Tincture - https://amzn.to/4fjafJZ  Hops Tincture - https://amzn.to/48gRhkT  Hops Capsules - https://amzn.to/3YBhNC8 For Cold/Depressed Types  Angelica (archangelica - American or sinensis - Chinese) - https://mountainroseherbs.com/angelica-extract and https://amzn.to/3Yz4dix  Black Cohosh - https://www.herbalist-alchemist.com/shop-products-bck-black-cohosh-extract For Tension Types  Blue Vervain - Verbena hastata - https://www.herbalist-alchemist.com/shop-products-bvv-blue-vervain-extract  Hops Tincture - https://amzn.to/48gRhkT For Dry/Atrophy Types  Shatavari (Asparagus racemosus) - https://mountainroseherbs.com/shatavari  Marshmallow Root - https://mountainroseherbs.com/marshmallow-root

Check out our recap and breakdown of Season 3 Episode 23 of the Big Bang Theory! We found 5 IQ Points!00:00:00 - Intro00:12:52 - Summary Begins00:14:33 - What is Lunar Ranging? 00:40:08 - Graphic Design is Science!00:53:13 - That wasn't in Frankenstein! 01:05:11 - Penicillin, life's greatest mistake01:38:25 - Did Leonard do the math right? Find us everywhere at: https://linktr.ee/theoreticalnonsense~~*CLICK THE LINK TO SEE OUR IQ POINT HISTORY TOO! *~~-------------------------------------------------Welcome to Theoretical Nonsense! If you're looking for a Big Bang Theory rewatch podcast blended with How Stuff Works, this is the podcast for you!  Hang out with Rob and Ryan where they watch each episode of The Big Bang Theory and break it down scene by scene, and fact by fact, and no spoilers! Ever wonder if the random information Sheldon says is true? We do the research and find out! Is curry a natural laxative, what's the story behind going postal, are fish night lights real? Watch the show with us every other week and join in on the discussion! Email us at theoreticalnonsensepod@gmail.com and we'll read your letter to us on the show! Even if it's bad! :) Music by Alex Grohl. Find official podcast on Apple and Spotify https://podcasts.apple.com/us/podcast/theoretical-nonsense-the-big-bang-theory-watch-a/id1623079414

C'est le quatrième et le dernier monument trail de l'année. Dans quelques jours, la 32ème édition de la Diagonale Des Fous va débuter. Cette épreuve, considérée comme l'une des plus compliquées au monde est même rallongée pour 2024. De quoi rendre cette course encore plus mythique, elle qui compte plus de 10.000 mètres de dénivelé positif et 175 kilomètres à parcourir ? Pour évoquer cette traversée de l'île de la Réunion, Benoît Boutron et Yohan Durand reçoivent le dernier vainqueur de la Diagonale Des Fous, Aurélien Dunand-Pallaz ! Avec lui, ils reviennent sur son état de forme, lui qui a récemment abandonné lors de l'UTMB. Comment se sent-il physiquement et mentalement ? Pourquoi a-t-il décidé de partir 5 semaines à la Réunion ? Et pourquoi cette course est tout simplement sa préférée ? Grâce à ce champion bienveillant, vous aurez également tous les bons conseils pour appréhender au mieux la Diagonale des Fous : conditions météo, équipements à prévoir, ravitaillements, dangerosité des chemins, allures à respecter : vous saurez tout ! La séance de la semaine, elle sera consacrée au retour d'un mythe : la montée du Maïdo et les 1800 mètres de dénivelé positif... pratiquement non-stop ! Comment doit-on appréhender une telle difficulté ? Et quelles sont les clés essentielles pour ne pas trop souffrir ?Et enfin, dans le bon plan matos, RMC Running vous permet de remporter trois tee-shirts ADN de la marque Sensus, la gamme running éco-responsable qui propose des vêtements encore plus légers et écologiques !

Après plus d'un mois sans donner de nouvelle sur le podcast, je suis enfin prête avec mes nouveautés.Je te fait un bilan sur comment s'est passée ma pause, entre péripéties et annonces :)J'avais besoin de parler avec toi avant de poster le premier épisode de Dimanche, en espérant que ton été s'est bien passé.Bande annonce officielle :Sur instagram : https://www.instagram.com/reel/C_qZTbcsClA/?igsh=OGhqbHY3bWE3bGdkSur tiktok : https://vm.tiktok.com/ZGeKxJnEf/(j'ai oublié de préciser je l'ai tourné entièrement à Copenhague

In this episode, we explore Autism developing in the embryo. We will review a couple Scientific papers discussing specific time frames of development within the embryo based on each trimester and specific cellular abnormal processes occurring. We will connect previous biological and environmental components and how it influences the creation of Autism and previous episodes of From the Spectrum podcast.Remember in the Cause of Autism episode- Light, Water, Magnetism, Periodic Elements, Vitamins, and Proteins because they are involved. During the episode, we review risk-genes and how this could be the wrong direction for Autism research. As a counter, I provide where research and funding needs to focus- pregnancy.Cause of Autism https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000662271496Eric Courchesne https://profiles.ucsd.edu/eric.courchesnePrenatal Origins of ASD: The When, What, and How of ASD Development https://www.cell.com/trends/neurosciences/fulltext/S0166-2236(20)30051-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0166223620300515%3Fshowall%3DtrueThe ASD Living Biology: from cell proliferation to clinical phenotype https://www.nature.com/articles/s41380-018-0056-yLeukocytes and Melanin Pigmentation https://core.ac.uk/download/pdf/81931995.pdfmTOR and PTEN https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743803/Cancer Drug for "Autism" https://neurosciencenews.com/asd-cognition-cancer-pharmacology-26481/0:00 Autism and the Embryo; Review of previous developmental milestones, and the processes and "ingredients" used in our Biology5:45 Cellular processes; ASD Living Biology; becoming the complex living organism8:17 1st Trimester: Proliferation, neurogenesis, migration8:46 2nd Trimester: Neurite overgrowth, synaptogenesis and synaptic function9:12 3rd Trimester: Neural networks9:33 Epoch 1 and 213:04 Scientific Literature; risk-genes; send research and funding to pregnancy17:57 Abnormal brain development in the embryo21:39 Excitation and the risk-genes and consequences to the Nervous System24:36 Be cautious of research direction; MEDICATION and MEDICAL PARADIGM RANT29:32 Connecting Light and Abnormal Development across the Body- Example Melanin and Leukocytes33:12 Recap on the Past 3 episodes36:00 Reviews/Ratings and Contact InfoX: https://twitter.com/rps47586Facebook: https://www.facebook.com/fromthespectrum.podcastEmail: info.fromthespectrum@gmail.com

RMC Running est heureux de vous proposer plusieurs épisodes consacrés à la course de trail running la plus mythique et la plus prestigieuse au monde : 171 km et 10 000 mètres de dénivelé positif pour faire le tour du Mont-Blanc ! Désormais appelé HOKA UTMB Mont-Blanc, cette épreuve traverse l'Italie, la Suisse et la France. L'objectif de ces podcasts est simple : suivre la préparation de ces athlètes, professionnels comme amateurs, qui vont s'engager sur cette traversée iconique, mondialement reconnue, et qui s'élancera le 30 août prochain. Cette semaine, Benoît Boutron et Yohan Durand reçoivent Mahauld Becker-Granier et Julia Harnie afin de faire le point sur leurs entraînements respectifs. Entre week-ends chocs, dénivelé positif et séance de renforcement musculaire, ces deux championnes se préparent pour l'évènement de l'année en trail. Le stress existe-t-il ? Sont-elles à 100% physiquement et mentalement ? Vous saurez tout !

Girls night!Our episode discussion this week includes Indiana Jones, the submarine controversy, Eat Pray Love, siding with Sheldon, slumber parties, finally getting in Penny's head, and more!Below are the two screenshots mentioned that Nicole sent Roxanne while recordingDownload hereRunning time: 1:11:44, 43.2 MB

3 Actions that Mark Your Commitment to Christ's Church--1 - Faith's Exaltation -8--2 - Faction's Eradication -9-11--3 - Friend's Excitation -12-15-

3 Actions that Mark Your Commitment to Christ's Church--1 - Faith's Exaltation -8--2 - Faction's Eradication -9-11--3 - Friend's Excitation -12-15-

3 Actions that Mark Your Commitment to Christ's Church1 - Faith's Exaltation (8)2 - Faction's Eradication (9-11)3 - Friend's Excitation (12-15)

In Part 2 of the Excitation and Inhibition phenomena, we discuss Metabolic "bank" account and demands of navigating the social world. We discuss if we have enough resources or if we will run a metabolic deficits (think burnout and avoidance, and social isolation). We cover NMDA and AMPA and different Autistic Phenotypes. In addition, we review Neuromodulators, which are vast in our biology and determine how and where to direct our attention and energy. Lastly, we discuss the medial Prefrontal Cortex and how it integrates the "self" with the outside world.Don't try to change an Autistic person because they are different than you or different than others. Don't let that offend your beliefs and capacity to apply critical thinking in life.https://www.nature.com/articles/s41398-023-02317-5https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723386/https://www.nature.com/articles/s41398-018-0155-1https://www.nature.com/articles/nature10360https://onlinelibrary.wiley.com/doi/full/10.1034/j.1601-183X.2003.00037.x?sid=nlm%3Apubmedhttps://www.nature.com/articles/s41380-022-01506-w(0:00) Introduction; Know Autism and Make Informed Decisions; Biological Aspects influencing Excitation / Inhibition Phenomena(4:30) Metabolic "Bank" Account and Resources; E/I creates criteria A and B; NMDA and AMPA, and more on the Striatum(10:02) Neuromodulators- Serotonin, Dopamine, Epinephrine and Norepinephrine, Acetylcholine; Active versus Passive Coping; Activating Systems and Cells and influencing Learning and Memory (Neuroplasticity); Nicotinic Receptors and Rapid-Excitation(15:20) medial Prefrontal Cortex (mPFC)- Metabolic demands and planning while considering Feelings, Integrating the Self and the Outside World; How E/I interacts; a brief explanation on Default Mode Network; Quieting the Body, or not; Information-Processing; Thalamocortical(20:19) Pursuits and Preference- Wanting and Having and being Autistic is fine, and others need to accept our phenotypes; sensory-input causes Faster Firing Rates in normal E/I- Image an imbalanced E/I(22:25) Wrap-up and understanding Autism, and Contact Info

En collaboration avec l'UTMB, RMC Running est heureux de vous proposer plusieurs épisodes consacrés à la course de trail running la plus mythique et la plus prestigieuse au monde : 171 km et 10 000 mètres de dénivelé positif pour faire le tour du Mont-Blanc en traversant l'Italie, la Suisse et la France. L'objectif ? Suivre la préparation de ces athlètes, professionnels comme amateurs, qui vont s'engager sur cette épreuve iconique, mondialement reconnue, et qui s'élancera le 30 août prochain. Cette semaine, Benoît Boutron reçoit trois personnalités féminines bien différentes, mais avec un objectif commun : le plaisir de courir en montagne. Maryline Nakache, lauréate de la TDS l'an dernier et du Marathon des Sables évoquera son nouveau mode de vie et ses ambitions futures. Récente huitième de la Diagonale des Fous, Julia Harnie expliquera sa préparation, elle, qui est également coach sportive ! Mahauld Becker-Granier, journaliste pour RMC, passionnée de trail, se confiera sur son impatience, mais également son stress de découvrir cette course si mythique de l'UTMB.Et enfin, Stanislas Gruau viendra nous donner de ses nouvelles, lui, qui a bouclé le Marathon de Paris il y a quelques jours !

In this episode, we discuss the Excitation and Inhibition Phenomena in Autism. There are many biological aspects implicating the E/I balance, and the Nervous System needs a healthy balance. This episode extends slightly downstream of the Genetic and Protein implications previously discussed. We discuss cortical and subcortical areas, sensations, introduce Glutamate and GABA, and discuss the critical period. The critical period is, pardon the pun, a critical period for Autism. In addition, we discuss BDNF and introduce neuroplasticity. Finally, we discuss Melanin and Melanopsin and sunlight and modern light, and the vast implications from our new environment. To end, we connect many modern diseases to these biological factors.See Dr. Jack Kruse Quantum Engineering 45Email: info.fromthespectrum@gmail.com

In this episode, we discuss common genetic and proteins implicated with Autism. This episode is all about preparing for a future episode about Excitation and Inhibition imbalance- a known phenomena with Autism. I play Tug-of-War with Barbed-Wire and talk about a critical factor of our environment implicating proteins and development- This is huge, and necessary. Genomic Architecture of Autism https://www.cell.com/cell/pdf/S0092-8674(22)01324-1.pdfPTEN and mTOR https://www.cell.com/cell-reports/fulltext/S2211-1247(22)01435-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124722014358%3Fshowall%3Dtrue16p11.2, Serotonin, and Possible Social Deficit Rescueshttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824539/https://www.nature.com/articles/s41586-018-0416-4https://www.nature.com/articles/s41386-021-01091-6https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606557/Dr. Jack Kruse on Autism https://jackkruse.com/category/autism/Cullin 3 / Cul3 https://pubmed.ncbi.nlm.nih.gov/31455858/SHANK3 https://pubmed.ncbi.nlm.nih.gov/?term=shank3Neurexin and Neuroligin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120877/https://www.sciencedirect.com/science/article/pii/S0092867414006734(0:00) Introduction; Excitation and Inhibition; (3:15) Phosphate and Tensin- Pten; Synapses, Soma Size, Migration, Cellular Spine Density, Dendritic Overgrowth, Myelination; mTOR (Rapamycin) and hope; Are cells doing what they should? (10:18) 16p11.2; Serotonin; Raphe and Nucleus Accumbens; Possible Therapeutic Help;(13:40) NEED TO KNOW INFORMATION; Tryptophan, Aromatic Amino Acids, UV-B Light and Proteins; Changes in our Light Environment and Implications to our Biology and Modern Health Concerns; Photoreceptors and Brain and Skin Connection- Neuroectoderm; Circadian Mismatch;(19:24) Back to 16p11.2 and Cortical Development;(22:00) Cullin 3 and Cul3 and Implications to Socialness and Sensory-Gating; Causes of Stereotypic Behaviors; Neuronal Excitability;(24:09) SHANK3; Tissues and Brain; Synaptic Implications; more Spine and Dendritic formation; Sensory Processing; Repetitive Behaviors; Anxiety; Social Deficits; Poor Motor Coordination;(25:59) Neurexin and Neuroligin; Synaptic development and action; Myelination; E/I and Spine; CNTNAP2 and mPFC(29:25) Wrap Up and Contact Informationemail: info.fromthespectrum@gmail.com

J-5. Ce dimanche 7 avril, plus de 60.000 coureurs vont arpenter les rues de la capitale à l'occasion du Marathon de Paris. Un soulagement pour la plupart d'entre eux avec l'aboutissement de trois mois de préparation. Parmi eux, les 4 heureux élus sélectionnés par RMC Running, à savoir les deux Camille, Benoit et Antoine. Comment se sentent-ils à quelques jours de l'évènement ? Physiquement et mentalement, sont-ils à 100% ? Malgré l'excitation, le stress peut-il faire son apparition ? Alimentation, hydratation, tenues vestimentaires : les derniers réglages sont-ils finalisés ? Ils disent tout à Benoît Boutron et Yohan Durand dans cet épisode hors-série consacré à la plus grande course de France ! Et enfin, Benoît Boutron et Yohan Durand vous donnent rendez-vous à deux reprises ce vendredi 5 avril. Vous pouvez venir assister à une conférence à 14h00 au salon du running ou bien venir rencontrer l'équipe le vendredi soir dans les rues de Paris grâce à Asics !

In this episode, my guest is Robert Greene, multiple New York Times bestselling author and expert on human psychology and behavior both at the individual and group levels and in the context of relationships, careers, and society. We discuss how to find, pursue and achieve one's unique life purpose, and how to best learn from good and hard experiences along that journey. We discuss power dynamics in relationships, the different types of human communication and the interplay between seduction and vulnerability. We discuss how to find the right romantic partner, improve healthy self-awareness, the link between anxiety and creativity, and pick ideal mentors and role models. Robert also discusses his recent stroke and what he has learned from his near-death experience about motivation, urgency and appreciation for life. Listeners of all ages will benefit from Robert's insights on navigating the process of building a deeply purposeful life and enhancing one's relationship with the self, others and society.  For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman ROKA: https://roka.com/huberman Helix Sleep: https://helixsleep.com/huberman Waking Up: https://wakingup.com/huberman InsideTracker: https://insidetracker.com/huberman Momentous: https://www.livemomentous.com/huberman Timestamps (00:00:00) Robert Greene (00:01:58) Sponsors: ROKA, Helix Sleep & Waking Up (00:05:56) Mastery (The Book), Purpose (00:08:26) Finding Purpose, Childhood, Learning & Emotional Engagement (00:18:00) Early Interests, Delight & Discovery (00:22:50) Love vs. Hate Experiences & Learning (00:28:25) Self-Awareness, Frustration, Excitation (00:31:47) Sponsor: AG1 (00:33:18) Sublime Experiences, Real vs. False; Authenticity & Time (00:43:57) Power & Relationships; Purpose & Mastery (00:55:51) Seduction, Vulnerability, Childhood (01:07:04) Sponsor: InsideTracker (01:08:05) Power Dynamics & Romance; Equality, Love Sublime & Connection (01:18:42) Vulnerability in Relationships, Creativity; Social Media, Justice (01:29:45) Outrage, Control, “Art of Ignore” (01:33:50) Masculinity & Femininity (01:42:16) Picking Role Models; Purpose & Mentor Relationship (01:51:07) “Alive” Thinking; Anxiety & Creativity (01:58:55) Convergent Interests & Romantic Relationships (02:07:19) Self-Awareness, Core Values & Romantic Relationships (02:15:27) Non-Verbal Communication & Relationships (02:24:58) Eyes, Voice, Intuition & Seduction (02:28:38) Virtual World, Social Skills, Non-Verbal Communication (02:32:19) Self-Awareness & Intelligence, Artificial Intelligence (AI), Nuance (02:41:43) Human Brain, Plasticity (02:45:18) Stroke & Near-Death Experiences, Self, Time (02:55:49) Appreciation & Near-Death Experience, Urgency (03:01:36) “Death Ground” & Urgency (03:09:13) Zero-Cost Support, Spotify & Apple Reviews, Sponsors, YouTube Feedback, Momentous, Social Media, Neural Network Newsletter Disclaimer

Introducing Zack and Amy! (0 Z, and 0 A)We kick things off with a bit of general TV discussion, including British TV, streaming vs network, and waiting years for new episodesOur episode discussion includes lots of gushing about Zack, Leonard and Penny being a mess on different pages, excitement over introducing Amy, and more!The TikTok Nicole talks about can be watched hereOur recording may continue to be sporadic for a bit, but watch for updates on twitter!Download hereRunning time: 1:06:30, 40 MB

Let's set off on an awe-inspiring journey with our guest, Cecilia Martinez, who, armed with self-awareness and an appetite for growth, has carved out a successful career in software development. Starting from her high school days, designing layouts for myspace pages, Cecilia's trajectory includes journalism, web development, and a self-discovery of her place in tech communities. Her story of growth and transformation, nurtured by her battles with ADHD, the trials and triumphs of a software development boot camp, and her blossoming career as a community lead at Replay, is nothing short of inspiring.What role can tech communities play in launching and shaping your career? Listen as Cecilia shares her experience exploring various local tech groups and the profound impact they had on her career. We examine the role of multi-channel outreach in creating diverse and representative communities and discuss how these communities can act as springboards for newcomers to the industry. Cecilia's narrative underlines the importance of aligning work with passion, the power of self-awareness, and the necessity to take calculated risks.From being a people pleaser to learning to push back when necessary, Cecilia shares the invaluable lessons she's picked up navigating her career paths. We discuss the decision-making processes involved in considering the next career move, the advantages of early-stage startups, and how she's grown to identify the most valuable work to do with her time. Cecilia also shares insights from her deep involvement with open source development tools and the influence these experiences have had on her career. Join us as she takes us through her journey of discovery and growth in the tech space.Use my special link https://zen.ai/dsVpYxjSth5fD-hlbzdIiw to save 30% off your first month of any Zencastr paidplan.Support the show

You never know what might happen when Rock & Roll Hall of Famer Mike Love pops into your tasting room.  For Seven Caves it was the beginning of an epic collaboration of spirts and flavors starting with today's beverage, Excitation.

Épisode en deux parties... voilà la première partie. Trouver l'amour lorsque l'on ne s'y attend pas, ça résume bien l'histoire de Colette. Son amour pour l'expatriation (malgré plusieurs échecs) mais aussi et surtout, son amour pour un Népalais !  Au départ, on va dire que Colette a un parcours classique. Elle fait ses études et évolue professionnellement en Île-de-France en allant d'une petite entreprise à une moyenne entreprise à une plus grande…Puis, 30 ans arrive. Elle a l'impression d'être au début de sa vie mais elle la trouve fade et elle pense qu'elle manque de saveur ! Pourtant, sur papier, cette vie semble parfaite. Mais elle va réussir à écouter sa boussole interne et ne pas se focaliser uniquement sur les apparences car elle souhaite être la meilleure version d'elle-même ! Elle commence par quitter son partenaire, qui, si elle se l'avoue, ne la fait pas vibrer même s'ils étaient en relation depuis 7 ans. Ensuite, c'est son emploi qu'elle va lâcher malgré le gros salaire qu'elle pouvait toucher. La voilà maintenant célibataire et au chômage ! Son état d'esprit à ce moment-là ? Excitation totale et fierté !  Elle va pouvoir se reconstruire en ouvrant le champ des possibles. Elle voit ce nouveau départ comme l'écriture d'une nouvelle aventure où elle va aller cocher des cases qu'elle n'aurait certainement même pas imaginer. Enfin… ce qu'elle aime surtout dire, c'est qu'elle ne va pas aller cocher des cases mais cocher à côté des cases car sa vision c'est :  “think outside de box” (pense en dehors des cases).  Elle va voyager et accepter des missions de freelance qu'elle n'avait pas vu venir. En y repensant, elle pense que l'univers était en train de la préparer pour la suite !  Puis à 37 ans, elle décide de partir avec deux copines pour une quête spirituelle, entre femmes, afin de prendre soin de son corps et de son esprit tout en découvrant une nouvelle culture.  Elle pensait qu'elle allait rencontrer beaucoup de personnes spirituelles mais finalement c'est l'amour qu'elle va rencontrer, 24h avant son vol retour pour la France ! Son mental occidental lui dit que ce n'est pas possible et pourtant, quand elle regarde Harry, elle se dit : “il a les yeux pleins d'étoiles et j'ai envie de nager dedans!”. Une histoire que l'on pourrait qualifier de conte de fée mais je ne vous en dis pas plus. Il vous suffit d'appuyer sur “lecture” pour découvrir cette belle histoire d'amour.  ---------------------------------------  

Épisode en deux parties... voilà la deuxème partie. Trouver l'amour lorsque l'on ne s'y attend pas, ça résume bien l'histoire de Colette. Son amour pour l'expatriation (malgré plusieurs échecs) mais aussi et surtout, son amour pour un Népalais !  Au départ, on va dire que Colette a un parcours classique. Elle fait ses études et évolue professionnellement en Île-de-France en allant d'une petite entreprise à une moyenne entreprise à une plus grande…Puis, 30 ans arrive. Elle a l'impression d'être au début de sa vie mais elle la trouve fade et elle pense qu'elle manque de saveur ! Pourtant, sur papier, cette vie semble parfaite. Mais elle va réussir à écouter sa boussole interne et ne pas se focaliser uniquement sur les apparences car elle souhaite être la meilleure version d'elle-même ! Elle commence par quitter son partenaire, qui, si elle se l'avoue, ne la fait pas vibrer même s'ils étaient en relation depuis 7 ans. Ensuite, c'est son emploi qu'elle va lâcher malgré le gros salaire qu'elle pouvait toucher. La voilà maintenant célibataire et au chômage ! Son état d'esprit à ce moment-là ? Excitation totale et fierté !  Elle va pouvoir se reconstruire en ouvrant le champ des possibles. Elle voit ce nouveau départ comme l'écriture d'une nouvelle aventure où elle va aller cocher des cases qu'elle n'aurait certainement même pas imaginer. Enfin… ce qu'elle aime surtout dire, c'est qu'elle ne va pas aller cocher des cases mais cocher à côté des cases car sa vision c'est :  “think outside de box” (pense en dehors des cases).  Elle va voyager et accepter des missions de freelance qu'elle n'avait pas vu venir. En y repensant, elle pense que l'univers était en train de la préparer pour la suite !  Puis à 37 ans, elle décide de partir avec deux copines pour une quête spirituelle, entre femmes, afin de prendre soin de son corps et de son esprit tout en découvrant une nouvelle culture.  Elle pensait qu'elle allait rencontrer beaucoup de personnes spirituelles mais finalement c'est l'amour qu'elle va rencontrer, 24h avant son vol retour pour la France ! Son mental occidental lui dit que ce n'est pas possible et pourtant, quand elle regarde Harry, elle se dit : “il a les yeux pleins d'étoiles et j'ai envie de nager dedans!”. Une histoire que l'on pourrait qualifier de conte de fée mais je ne vous en dis pas plus. Il vous suffit d'appuyer sur “lecture” pour découvrir cette belle histoire d'amour.  ---------------------------------------  

Today, we're going to talk about the 15 depression symptoms you may not know about. My hope is that it will help you, number one, understand your symptoms, and number two, get help faster. Let's do this. Let's get started.  I hope you are well. I hope you are kind and gentle to yourself today. I hope you are taking moments to notice that the trees are changing, the leaves are changing, and spring is here. If you're in the Northern Hemisphere, maybe the weather is changing. Also, if you're in the southern hemisphere, my lovely friends in Australia, I just want to remind you to stop and take note of the weather. It can be one of the most mindful activities we engage in, and it can help us be grounded in the present instead of thinking forward, thinking backward, and ruminating on the past and the future.  I hope you can take a minute. We can take a breath right here... and you can actually take in this present moment before we get started.  Today, we're talking about 15 depression symptoms you may not know about. As I said in the intro, my hope is that these symptoms help you understand what's going on for you if you're depressed or help you get help faster.  Mnemonic For Depression Symptoms Now, some of you may really have a good understanding of depression symptoms. Some of you may know the common ways that it shows up, so I will first address those just to make sure you've got a basic understanding of common depression symptoms. I'm going to actually give you a mnemonic for depression symptoms. I find it's very helpful to have this on hand when I'm assessing my clients and my patients. It's a really good check-in even for myself like, what's going on? Could this be depression? Let's go through this mnemonic for depression.  D is for depressed mood. I think we all know about that one. That's a very common Hollywood way of understanding people who are sad, feeling very down, and so forth. We mostly all know the D for depression.  E is for energy loss and fatigue. In fact, I did a poll on Instagram. For those of you who don't follow me, go ahead and follow me @youranxietytoolkit. I did a poll and I asked, what are the most painful parts of depression, and the most common response was complete fatigue, complete exhaustion, just overwhelming tiredness and energy loss. I think that that's a really common one. It can be confusing because you're like, “What's going on?” It makes you feel like maybe there's a medical condition going on, but often it is depression. The P is for pleasure loss. Now, this is an important one that we look for in clinical work as we're looking for. Is the person with depression completely at a loss and they're not enjoying the things they used to? Are they struggling to get joy out of even the most joyful things that they used to find joyful? That's a very common one.  The R is for retardation or excitation. What we're talking about there is moving very slowly, like a sloth pace or even just sitting there and staring and unable to move your body completely, inability to get motivated to move. Excitation is the other one, which is like you feel very jittery and you feel very on edge and so forth.  The E is for eating changes such as appetite increase or decrease, or weight increase or decrease. Again, common symptoms for depression.  The S is for sleep changes. It is very common for people with depression to either want to sleep or need to sleep all day, again, because of that energy loss. Or they lay awake for hours at night staring at the roof, unable to sleep, experiencing sleep anxiety, which can often then impact their sleep rhythm. They're sleeping all day, staying awake all night, or vice versa, but in a very lethargic way.  The next S is for suicidal thoughts or what we call suicidal ideation. These are thoughts of death, thoughts of dying, and sometimes plans to die. If that is you, please do go and see a mental health professional immediately or go to your ER or call the emergency in whatever country you are. For America, it's 911. Suicidal thoughts are very, very common with depression. We have two types of suicidal thoughts in depression, and that's usually passive suicidal thoughts and then active suicidal thoughts. Passive is thoughts of death, but you just want to crawl under a rock and just go to sleep and never wake up. Active suicidal thoughts is where you're actually wishing to die. It's important to differentiate, and clinically, we do make some changes depending on which is which.  The I for depression is “I am a failure.” This has a lot to do with shame or loss of confidence and self-esteem issues. “I am a failure” is a big one that often doesn't get disclosed until the person is in therapy. We even did an episode a couple of weeks ago. Depression Is A Liar was the title. Depression tells you all these lies. It tells you you're a failure and you start to believe it. It tells you there's something wrong with you and you start to believe it. That is a very common part of having depression.  The O is “only me to blame,” and this is what we call guilt. With depression, often people will feel guilty for everything, feel guilt & regret all day, every day. “I'm not a good mom,” “I'm not a good friend,” “I'm not a good talk daughter,” “I'm not a good employee,” “I'm not a good boss,” whatever it may be. And then they blame themselves, punish themselves, and a lot.  The N is for no concentration. Again, when I did the poll on Instagram, so many people posted that they just cannot think, they can't plan, they can't concentrate, they can't learn if they're in school, they can't stay focused on a conversation. These are all very common symptoms of depression that may be impacting you either a little bit or, in many cases, an immense amount. They're the most common. That's a mnemonic for depression symptoms. They're the most common that we assess for. But now I want to go into the 15 depression symptoms you may not know about.  The way that I'm structuring this podcast episode is I've broken it down into different categories of people. But what I want you to recognize before we go down is these are not specific to only these categories of people because it depends on the person. We have to be very person-centered when it comes to looking at depression and diagnosing depression and treating depression because there's no one way to have depression. I don't want to miscategorize any of this. I'm just talking very generally, so I want to give a disclaimer as I go through these different categories or groups of people. Please note that it's probably true for everybody. It's just more common in these groups.  Before we get started, I want to remind you. I know I did an announcement. I want to remind you, the Overcoming Depression Course is going live on March 11th. This is very exciting. This is a live online course that I am teaching live on Zoom. I will be teaching you over the course of three different weekends on Saturday mornings from 9:00 to 10:30 on March 11th, March 18th, and March 25th, 2023. If you want to sign up and come and learn from me, I'll be going through five major areas in which you can make changes related to depression. I will be giving you all of this psychoeducation upfront. There will be a workbook that you can use on your own to really put the skills and tools and strategies into place. If you're interested in joining us, may I say again live, head on over to CBTSchool.com/Depression. It'll take you to the page. You can sign up there and then I will send you via email all of the information you need to be there for our live conversations. You can ask questions in the chat box. My hope is to double down with motivating you, inspiring you, educating you, and getting you feeling a little more confident on what to do if you're struggling with these symptoms. My hope is to help you see that depression is a liar and you can break free!  Here we go.  Depression Symptoms In Men Again, I'm speaking generally here, and I really want to be careful here because it's definitely not just men who experienced this, but I did a lot of research for this episode and these were the statistics that I found to be most common in these areas.  Anger, irritability, or aggressiveness That's not in the mnemonic for depression that we went over. A lot of times people miss this core symptom, which is anger, irritability, or aggressiveness. Now, is it only men? Absolutely not. I want to be really clear here, that is absolutely not the case, but I think because of the stigma for men around showing sadness or showing depression, they have shown that men tend to express it in a different way, because sometimes men don't feel comfortable crying in public with their friends or loved ones. Not always true. Again, I'm going to keep saying not always, but I think that's a cultural expectation put on men and therefore it does come out when in the form of anger, irritability, or aggressiveness. Irritability is a huge one when it comes to depression that I have seen clinically.  Problems with sexual desire and performance This is, again, not just for men, but common in the research for men is common problems with sexual desire and performance. A lot of men and women, but again, I don't want to be excluding anyone here, have found that they either have a massive lack of sexual desire or struggle to reach arousal, struggle to reach orgasm. We are going to be addressing this in-depth here in the next couple of months and I'm going to put a lot of energy into making sure we address how much it impacts people and sex. Stick around for that. I'm super excited. But there is another common depression symptom you may not know about. Sometimes we think it's anxiety that causes that, but it's not just anxiety; it can be depression too.  Engaging in high-risk activities Again, not just for men, but it has been shown to be more prevalent in men. High-risk activities, spending a lot of money, driving fast in cars, gambling, drug use, and so forth. Again, not just in men, but this is another common depression symptom you may not know about and maybe diagnosed and put in a different category when really the person is deeply depressed and trying to feel pleasure. Remember we talked about the mnemonic P is for pleasure loss. Often we engage in these high-risk activities because we're just desperate to feel that sense of pleasure and exhilaration again.  A need for alcohol or drugs Again, not just men and I will discuss this in other categories as well, but it is common that an increased use of alcohol and drugs could be a sign that you are getting an increased level of depression. Then what happens is when you're using a lot of alcohol and drugs, you usually have a hangover or some kind of side effect to that which makes you feel more depressed, which then makes you feel more like you need to have more alcohol and drugs. Again, it's a cycle that can really cause a lot of chaos in people's life and could be simply the first symptom or way to cope with depression.  Depression Symptoms In Women Women are twice as likely to develop depression than men. That's a statistic I didn't know. Up to 1 in 4 women are likely to have major depressive disorder or major depression at some point in their life. 1 in 4, that is so high. We have to make sure we're catching people and helping people with this massive issue.  Premenstrual Dysphoric Disorder Prementstrual Dysphoric Disorder involves a massive influx of depressive symptoms right before your period or at specific stages of your menstrual cycle. Very common. In fact, again, we're going to be addressing this very soon on the podcast as well. These are some areas I feel like I have completely missed as your podcast host, so I want to really make sure we're targeting and addressing these issues as we move forward.  Perinatal Depression Perinatal depression occurs around pregnancy before or after pregnancy starts.  Perimenopausal Depression Perimenopausal depression is around the menopausal period for people going into menopause.  These are common symptoms of depression that get missed all the time or get misdiagnosed or underdiagnosed when the person is really suffering.  A lot of people who follow me have said they've gone to their doctor to share how they get this massive influx of depression before their period or in their cycle, and the doctor has blown them off and said, “Eat more celery juice,” or “Exercise more.” While, yes, exercising can be helpful for depression, we are missing a major depression symptom, and I want you to be informed about those. Depression Symptoms In Kids Oh, the kiddos. It's so hard on the kiddos. In fact, one of the reasons I have been so hyped on talking about depression was, in August of last year, my daughter went in for her yearly checkup with her pediatrician and the pediatrician insisted on doing all of these mental checklists with her. I was saying to her, “Is this really necessary? She's doing fine. To what degree are you scaring her?” She said, “Oh, you have no idea the degree of depression in children since COVID.” “I had no idea and I'm a mental health professional. How did I not know this?” She said, “Yeah, it's everywhere in kids, and kids are really good at hiding it.” I literally sank in my chair like, “How did I miss this? How did I not know this?” We talked about it a lot and I think it's really important that we understand that depression symptoms in kids often look like what we call in some societies like naughty kids. Again, let's go through them.  Big emotional outbursts  When we see kids on the playground having big outbursts, big anger responses, again, we talked about that before, sometimes they get labeled as the naughty kids. Well, guess what? We've got to make sure we check to make sure they're not depressed. Because that is a symptom of depression.  Difficulty initiating and maintaining social relationships Again, after COVID, a lot of parents I've heard have said, “Oh, I think they just lost their ability to make friends during COVID,” which I totally get. We had to train my son after COVID to follow basic social cues because he hadn't seen people in so long. But again, we have to keep an eye on whether this is a symptom of depression in children.  Extreme sensitivity to rejection or failure This one is so important not just for kids, but for teens, adults, everyone. With depression, we all have sensitivity to rejection of failure. No one wants that. But often a symptom of depression is extreme sensitivity and absolute devastation about getting rejected for, let's say, a school play or to be picked in soccer or they had a big issue with a test or so forth. They have a strong, strong reaction to that.  Frequent absences from school and/or a sudden decline in grades If kids got a massive decline in grades or they started refusing to go to school, my instinct is to always say, “Oh, there's some anxiety going on. They're anxious. They don't want to go to school, they must be ‘avoiding school' because of anxiety as a compulsion.” Well, guess what? It could be depression, and let's make sure we assess these kiddos correctly. This is true for adults as well. If we're depressed, we don't want to go out, we don't want to go to the show on Friday night, we don't want to hang out with friends. That makes sense as well.  Depression With Somatic Symptoms This is probably the most important one. Very common symptoms of depression include headaches, stomach ache, muscle pain, sore back. These are very common physical symptoms of depression and ones that we have to make sure that we aren't ignoring to make sure that they get the care. A lot of people go into the medical system complaining of physical symptoms only to find out that nothing is wrong and they can't understand it, and it could be depression. Not always—please always go and get a medical checkup—but it could be.  Depression Symptoms In Teens All of the symptoms I've shared above could be present in teens as well. Like I said, these are not categories that are only just for these categorical lots of people.  General overwhelming sense of apathy Commonly with teens is this general overwhelming sense of apathy like, “I don't care. I don't care about you, I don't care about me, I don't care about school.” Often parents can interpret this as like, “Oh my god, my kid is horrible.” But again, we have to make sure we're assessing for depression first. Excessive guilt I did have that as the mnemonic under O (only me to blame), but this shows up a lot in kids and teens—excessive saying I'm sorry, excessive apologizing, feeling hyper-responsible for everything that happens, feeling hyper-responsible for the social issues and drama that's happening at school, ruminating a lot about that. Again, this is common for anybody, very common for anybody with depression as well, but with teens, it really does start to spike.  Preoccupation with death or on death Again, this could be true for other categories or any human being, but we do see it show up a lot in teens—a preoccupation on death regarding movies, music, shows, or books they're reading. Just really a heavy focus on things related to death or very dark, dark topics, aggressive topics. This can play out in many ways. Again, it could also be very normal behavior and that could be something that brings them great pleasure. But again, I'm only bringing it up because these are common unknown depression symptoms that you don't possibly know could be a symptom of depression. I think it's better to be educated than to ignore it and not know.  That's the 15 depression symptoms you may not know about. One thing to consider, and I did touch on this during the episode, is commonly we have to look at depression symptoms versus anxiety symptoms. The truth is, many of these are also symptoms of anxiety. Let's go through some of them. Anger, irritability, aggressiveness—true for anxiety. Sexual desire—true for anxiety, engaging in high-risk activities—true for anxiety. A need for alcohol and drugs—true for anxiety. We do notice some perinatal symptoms and perimenopausal symptoms impact anxiety as well, but we're specifically weren't speaking to those today. But if we move into the kids category: outbursts, difficulty maintaining relationships, sensitivity to failure, frequent absences, somatic symptoms, guilt, apathy, preoccupation—these are also very common in anxiety.  What I want you to leave with today is this: Take everything you learnt today. I hope that this didn't create more anxiety for you. Just take it as knowledge. Take it as something you now know so that you can be an informed consumer, an informed patient, an informed client with your therapist so that you can know. I will say, if I'm speaking completely vulnerably, reading all the research I did made me very anxious because I have a close to teen child and I was thinking, oh my gosh, what happens if this starts to go down this track and looking at the statistics of suicide and so forth. It is anxiety provoking. But what I did in that moment—and if this helps you, I hope it does—is I said to myself, “Kimberley, you're better to be informed and practice not ruminating and doing mental compulsions about this and catastrophizing than you are to not know at all.” Here I have an opportunity to practice all of the response prevention skills, the mindfulness skills, the self-compassion skills that I have in my tool belt and that you hopefully have in your tool belt if you've been a long-term listener here on Your Anxiety Toolkit. We're going to use those tools to help us manage this, but we're going to practice being an informed consumer here. I hope this has been helpful. They are the 15 depression symptoms you may not know about and now you know.  Thank you, guys. I'm so happy to be here with you today. Stick around because some pretty exciting things are coming up. A lot of you know we had the mental compulsion series last year. This year, we are having a full sexual health related to mental health series that is just around the corner. It is going to be so incredible. I have some amazing doctors, psychiatrists, sex therapists, educators coming on to talk specifically with you around specific issues, around sexual health related to anxiety and depression. I'm so, so excited, so proud, and so honored to get to do this work with you.  All right, I'm going to hit the road. Have a wonderful day. It is a beautiful day to do hard things, and I'll see you next week.

In this episode, I discuss the physiology of smooth muscle cell contraction and how it differs from skeletal muscle cell contraction. 

In this episode, we review the high-yield topic of Spread of Excitation from the Cardiovascular section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://anchor.fm/medbulletsstep1/message

Broads Next Door Episode 2: You're Being Hysterical In this episode we get into sleepover rituals, stuff we watched when that we shouldn't have as kids, cases of psychogenic illness & the most popular (vibrating) myth about curing female hysteria. Sources: Barker, K. Brandon, and Rice, Claiborne. 2012. "Folk Illusions: An Unrecognized Genre of Folklore." Journal of American Folklore Bartholmew, Robert. 2009, Little Green Men, Meowing Nuns & Head Hunting Panics Butkus, Cathy Jo. 1977. “Ouija Whirlwind.” Fife Folklore Archive, Utah State University. Comella, Lynn 2017. Vibrator Nation Cursed History, Cat Nuns of France, YouTube Didion, Joan. 2011. Blue Nights Dodson, Bette. 2016. Sex by Design: The Betty Dodson Story Ellis, Bill. 1994. Speak to the Devil: Ouija Board Rituals Among American Adolescents Gandes, Alan. 2002. Bloody Mary in the Mirror: A Ritual Reflection of Pre-Pubescent Anxiety Prefrontal Lobotomy in the Treatment off Mental Disorders (GWU, 1942) Lieberman, Halley, 2020. (Almost) Everything You Know About the Vibrator is Wrong Lieberman, Halley, 2017. Buzz: The Stimulating History of the Sex Toy Maines, Rachel. 2001. The Technology of Orgasm Morley, Carol, 2014 Mass Hysteria is a Powerful Group Activity National Geographic, Cleopatra's Vibr. YouTub Beattie M, Lenihan P (2018). Counselling Skills for Working with Gender Diversity and Identity. London: Jessica Kingsley Publishers Rhode Island Medical Journal, Psychiatric Casualties of The Exorcist, 1974 Nerve-Vibration and Excitation, J. Mortimer Granville, M.D. J &A Churchill, 1883 --- Send in a voice message: https://anchor.fm/broadsnextdoor/message Support this podcast: https://anchor.fm/broadsnextdoor/supportThis show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/5803223/advertisement