Podcasts about mechanisms

What causes kidney stones to form, and why are they becoming increasingly common? In Part 1, David S. Goldfarb explores the physiological mechanisms behind kidney stone disease, the evolving roles of diet, metabolism, and hydration, and the links between kidney stones and broader metabolic conditions, including metabolic syndrome and fatty liver disease. He also reflects on how advances in research have transformed our understanding of risk factors, genetics, and disease prevention.

reference: Sri Aurobindo and the Mother, The Psychic Being — Soul: Its Nature, Mission and Evolution, Section 4 The Afterlife and Rebirth, pg. 127This episode is also available as a blog post at https://sriaurobindostudies.wordpress.com/2026/07/17/the-occult-mechanisms-behind-birth-and-death/Video presentations, interviews and podcast episodes are allavailable on the YouTube Channel https://www.youtube.com/@santoshkrinsky871More information about Sri Aurobindo can be found at www.aurobindo.net  The US editions and links to e-book editions of SriAurobindo's writings can be found at Lotus Press www.lotuspress.com#Sri Aurobindo #The Mother #yoga #integral yoga #spirituality #soul #psychic being #rebirth

Continuing his exploration of once-weekly insulins, Neil Skolnik speaks with Aaron King, MD. Together, they cover the mechanisms, practical considerations, and the myriad benefits that this new therapy can have over daily basal insulin. This special episode is sponsored with support from Novo. Please listen to the episodes by clicking on the podcast player below or by freely subscribing to Diabetes Core Update via Apple Podcasts, Amazon Music, Spotify, or your preferred podcast platform. Presented by: Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Aaron King, MD. Trained in the United States Navy in Family Medicine and certified by the American College of Diabetology, Dr. King practices outpatient diabetes management in San Antonio, Texas. Selected references: Weekly Icodec versus Daily Glargine U100 in Type 2 Diabetes without Previous Insulin. N Engl J Med 2023;389:297-308 Weekly Fixed-Dose Insulin Efsitora in Type 2 Diabetes without Previous Insulin Therapy. N Engl J Med 2025;393:325-335

Haystack Full of Needles: A memoir of research on mechanisms of memory in the decades that defined neuroscience by Louis Neal Irwin https://www.amazon.com/dp/1664140603 Lirwin.org How do we store information in the brain? Is memory a thing in a place, like a specific molecule in a particular cell? Or does learning require a process in a population, like neurons firing in a specific pattern for each experience? This combination of memoir and history tells the story of how the mechanisms of memory were gradually revealed, through biographical vignettes of the scientists who set out to solve the riddle of memory, including the author?s own efforts as he was coming of age as a scientist. It shows how individual goals intertwine with the technologies at hand to push scientific knowledge forward, often erratically, and always in the context of social forces and private ups and downs. Not only a compelling personal story with the war in Vietnam, civil rights movement, and downfall of two presidents as backdrop, this is a lucid explanation of brain function for the nonscientist and valuable contribution to the history of science in the decades that saw neuroscience join molecular biology as the marquee biomedical accomplishments of the twentieth century About the author Writer, neuroscientist, astrobiologist, educator, and political activist. Born in West Texas and raised in San Antonio, now current resident of Denver. Former Professor and Chair of Biological Sciences at the University of Texas at El Paso. Previously lived in Lubbock TX, Lawrence KS, New York City, Detroit, and Newton MA, serving four terms there on the Board of Aldermen. Recently a Court Appointed Special Advocate for abused and neglected children, and current chair of the Public Policy Committee of the Democratic Party of Denver. Co-author of “Life in the Universe” and “Cosmic Biology”, and author of “Scotophobin”

In the biotech industry, advancing cell-based therapies is not just about innovation. It's about solving real gaps where conventional treatments fall short, especially against complex, aggressive tumors.In this episode of the Smart Biotech Scientist Podcast, host David Brühlmann welcomes Jun Yung Woo, Co-Founder of AGEM Bio, who offers an in-depth look at the science and strategy behind engineered mesenchymal stem cells (MSCs), with a focus on why glioblastoma is the right proving ground for the platform.Topics discussed:Why glioblastoma is the right Phase I indication: infiltrative growth, immunosuppression, and STING pathway deficiencies that make GBM uniquely suited to the platform (02:43)The surgical workflow: intracavity MSC delivery during tumor resection, oral 5-FC administration, and how engineered cells act as local bioreactors in the resection cavity (04:05)Mechanisms by which engineered MSCs target heterogeneous and invasive tumors through shared vulnerabilities rather than antigen recognition (05:58)Overcoming immune rejection with allogeneic therapies and the unique immunological profile of MSCs (07:32)Manufacturing and scale-up: addressing donor variability, GMP production, and building a reproducible process (09:16)Why GMP manufacturing should be designed in from the earliest stages of research (10:50)Beyond glioblastoma: expanding the platform to other solid tumors, regenerative medicine, and chronic inflammatory disease (11:27)Strategies for international trial expansion and partnerships beyond Singapore (12:41)Reframing MSCs from stem cell therapy to programmable delivery platform: the MSC 2.0 thesis (14:10)Smart insight: The shift Jun Yung articulates is from treating stem cells as the therapy to treating them as programmable therapeutic vehicles. Once you can reliably engineer, manufacture, and preserve their function, the limitation is no longer what the cell naturally does. It becomes what biology you can encode into it. Glioblastoma is the proving ground, and the platform's reach extends to liver cancers, sarcomas, peritoneal malignancies, and chronic inflammatory disease.These episodes expand on the same themes of MSC biology, cell engineering, and the challenges of scaling consistent, functional cell therapies:Episodes 179 - 180 : How Mesenchymal Stromal Cells Are Transforming Care for Diabetes and Autoimmune Diseases with Lindsay DaviesEpisodes 253 - 254: How to Source, Manufacture, and Scale the Earliest Stem Cells for Allogeneic Cell Therapy Without Ethical Barriers with Yuta LeeEpisodes 125 - 126: How to Enhance Cell Engineering Using Mechanical Intracellular Delivery with Armon ShareiEpisodes 129 - 130: Revolutionizing Cell Therapy Manufacturing: Reducing Costs to Reach More Patients with Jason FosterConnect with Jun Yung Woo:LinkedIn: www.linkedin.com/in/junyungwooAGEM Bio website: www.agem.bioEmail: yung@agem.bioSupport the show

Guest: Dr. Jennifer Francis, Woodwell Climate Research CenterWhen we think about the Arctic, it's easy to picture a remote landscape of sea ice and polar bears. But what happens in the far north doesn't stay there. As the Arctic continues to warm at an unprecedented pace, scientists are uncovering how those changes may be influencing weather patterns across the Northern Hemisphere—from prolonged heat waves and persistent droughts to heavy rainfall and unusual swings in the jet stream. Today on Weather Geeks, we're joined by atmospheric scientist Dr. Jennifer Francis, whose pioneering research has helped shape our understanding of the connection between Arctic climate change and the behavior of the jet stream. We'll explore why the Arctic is warming so rapidly, how those changes can ripple through the atmosphere, and what they may mean for the persistent weather patterns we've seen in recent years—including the extreme heat that has gripped much of Europe this summer.Chapters00:00 Dr. Jennifer Francis's background and interest in weather05:22 Jet stream patterns and their role in extreme weather13:21 Break 114:31 Mechanisms of Arctic amplification and feedbacks22:57 Stratospheric polar vortex and winter weather effects25:04 Break 225:58 Summer jet stream behavior and climate connections32:08 Ocean heat waves and their influence on jet stream patterns34:33 Current research and future challenges in Arctic climate studies37:06 Closing remarks and resourcesResourcesWoodwell Climate Research Center - https://www.woodwellclimate.org/Jennifer Francis - Research Profile - https://www.woodwellclimate.org/our-scientists/jennifer-francis/Clausius-Clapeyron Relationship - https://en.wikipedia.org/wiki/Clausius%E2%80%93Clapeyron_relation Guest linksTwitter - https://x.com/WoodwellClimate https://x.com/JFrancisClimateResearch Center - https://www.woodwellclimate.org/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is There a Nexus Existing Between The Orchid Flower and The Elderly People? An Interdisciplinary, Theological, and Metaphorical Reflection. © 2026. ISBN 978-976-97997-3-8.mp3AbstractThis scholarly conversation explores whether a meaningful nexus exists between the orchid flower and elderly people. Rather than presenting a biological comparison, the discussion develops a metaphorical, theological, philosophical, and interdisciplinary framework informed by media arts, cultural theory, environmental appreciation, and Christian devotion. Orchids and elderly people occupy distinct kingdoms of life; however, both exemplify beauty, resilience, diversity, adaptation, and intrinsic worth. Through the integration of botanical history, gerontology, biblical theology, and cultural symbolism, this essay argues that orchids provide an illuminating metaphor for understanding aging with dignity. Ultimately, the comparison invites readers to reconsider cultural assumptions about age while affirming that every stage of life reflects God's creative wisdom. All things being considered it should be noted that the social constructs  orchids, elderly, aging, metaphor, theology, ecology, cultural theory, are media arts are critical to this discourse.Dr. William Anderson Gittens, Doctor of DivinityReferencesBoyce, W. T., & Ellis, B. J. (2005). Biological sensitivity to context: I. An evolutionary–developmental theory of the origins and functions of stress reactivity. Development and Psychopathology, 17(2), 271-301. https://doi.org/10.1017/S0954579405050145Duke Science & Society. (n.d.). Does race exist? https://scienceandsociety.duke.edu/does-race-exist/Ellis, B. J., Boyce, W. T., Belsky, J., Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2011). Differential susceptibility to the environment: An evolutionary–neurodevelopmental theory. Development and Psychopathology, 23(1), 7-28. https://doi.org/10.1017/S0954579410000611Gittens, W. A. (2026). The orchid flower and the elderly people. ISBN 978-976-97942-2-1.Harper, D. (2020).Online Etymology Dictionary. Retrieved from https://www.etymonline.comHistorical race concepts. (n.d.). Simple English Wikipedia. https://simple.wikipedia.org/wiki/Historical_race_conceptsHoly Bible, New International Version. (2011). Zondervan. (Original work published 1973)How many major races are there in the world? (2020). Academia.edu. https://www.academia.edu/40682024/How_many_major_races_are_there_in_the_worldKremen, W. S., Lachman, M. E., Pruessner, J. C., Sliwinski, M., Wilson, R., & Seeman, T. (2012). Mechanisms of age-related cognitive change and targets for intervention: Social interactions and cognitive reserve. Neuropsychology Review, 22(4), 466-475. https://doi.org/10.1007/s11065-012-9201-9Kremp Florist. (n.d.). Guide to the orchid flower family. https://www.kremp.com/pages/guide-orchid-flower-family-articlesOrchid. (n.d.). Wikipedia. https://en.wikipedia.org/wiki/OrchidOxford English Dictionary. (2023).Nexus. Oxford University Press.Pluess, M., & Belsky, J. (2013). Vantage sensitivity: Individual differences in response to positive experiences. Psychological Bulletin, 139(4), 901-916. https://doi.org/10.1037/a0030196Pridgeon, A. M. (2001).The Illustrated Encyclopedia of Orchids. Timber Press.Race and genetics. (n.d.). Wikipedia. https://en.wikipedia.org/wiki/Race_and_geneticsRoyal Botanic Gardens, Kew. (n.d.). Orchidaceae. https://powo.science.kew.org/Royal Horticultural Society. (n.d.). Orchid facts. https://www.rhs.org.uk/plants/types/houseplants/orchid-factsStearn, W. T. (1992).Botanical Latin. Timber Press.Stern, Y. (2012). Cognitive reserve in ageing and Alzheimer's disease. The Lancet Neurology, 11(11), 1006-1012. https://doi.org/10.1016/S1474-4422(12)70191-6Theophrastus. (1916). Enquiry into plants (A. Hort, Trans.). Harvard University Press. (Original work written ca. 300 BCE)World Health Organization. (2024). Ageing and health. https://www.who.int/news-room/fact-sheets/detail/ageing-and-healthSupport the showCultural Factors Influence Academic Achievements© 2024 ISBN978-976-97385-7-7 A_MEMOIR_OF_Dr_William_Anderson_Gittens_D_D_2024_ISBNISBN978_976_97385_0_8Academic.edu. Chief of Audio Visual Aids Officer Mr. Michael Owen Chief of Audio Visual Aids Officer Mr. Selwyn Belle Commissioner of Police Mr. Orville Durant Dr. William Anderson Gittens, D.D En.wikipedia.org/wiki/Lifelong_learning Hackett Philip Media Resource Development Officer Holder, B,Anthony Episcopal Priest,https://brainly.com/question/36353773https://en.wikipedia.org/wiki/Lifelong_learning#cite_note-19https://en.wikipedia.org/wiki/Lifelong_learning#cite_note-:2-18https://independent.academia.edu/WilliamGittens/Bookshttps://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=william+anderson+gittens+barbados&oq=william+anderson+gittenshttps://www.academia.edu/123754463/https://www.buzzsprout.com/429292/episodes. https://www.youtube.com/@williamandersongittens1714. Mr.Greene, Rupert

Are you interested in how regeneration can help old urban areas? Debate of the article titled Driving mechanisms of green regeneration in old industrial areas under ecological security constraints: Evolutionary game theory oriented toward public satisfaction from 2024, by Yang Zhang, Chang Liu, and Caixia Hou, published in the Journal of Urban Planning and Development.This is a great preparation to our next interview with Andy Roberts in episode 446 talking about regenerative design principles. Since we are investigating the future of cities, I thought it would be interesting to see what mechanisms can drive green regeneration in aging industrial districts. This article suggests that achieving sustainable urban transformation requires a balance of public supervision, strategic subsidies and strict environmental regulations.Find the article through this link.Abstract: Old industrial areas have numerous ecological safety problems, requiring green regeneration to mitigate related risks. This study considered the impact of public participation and willingness to adopt green regeneration of old industrial areas and developed an evolutionary game model for the local government and developers. Then, we analyzed the initial strategy and relevant variables of the game through MATLAB (version 2021a) simulation to inform the establishment of green regeneration of old industrial areas. The study results showed that public willingness to use regenerated industrial areas and green preferences could motivate the adoption of green regeneration among developers. The incremental cost of ecological restoration of old industrial areas considerably hinders developers from opting for green regeneration. When the incremental cost exceeds the government's financial subsidies and policy preferences, developers often opt for traditional renovation. Furthermore, punitive measures enforced by local government against developers were found to be more effective than incentives; when the cost of punishment exceeds the incremental cost of ecological restoration, developers often opt for green regeneration. Although the ecological safety concerns in old industrial areas can prompt local governments to opt for stringent regulations and developers for green regeneration at the beginning of the game model, evolutionary stability is not reached.Connected episodes you might be interested in:No.266 - Interview with Alison Whitten about regenerative urban practicesNo.295R - Critical success factors for public-private partnerships in urban regeneration projectsNo.438 - Interview with Joris de Leeuw about regenerating urban ecosystems and food forestsYou can find the transcript through ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠th⁠i⁠⁠⁠s link⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.What was the most interesting part for you? What questions did arise for you? Let me know on Twitter ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@WTF4Cities⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or on the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠wtf4cities.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ website where the⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠showno⁠t⁠es⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠are also availableI hope this was an interesting episode for you and thanks for tuning inEpisode generated with ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Descript⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ assistance (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠affiliate link⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠)Music by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Lesfm ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Pixabay

In today's video I discuss my favorite mechanisms in new-to-me games and expansions so far in 2026.   https://youtu.be/7pLyT7R1iyo

Broadcast from KSQD, Santa Cruz on 7-09-2026: Researchers refined a technique to reverse skin cell aging by about 30 years while preserving cellular identity. Exposing adult fibroblasts to Yamanaka factors—stopping before full reversion to pluripotent stem cells,reset the epigenetic clock and gene expression patterns to resemble much younger cells. The rejuvenated fibroblasts produced significantly more collagen, migrated faster to close artificial wounds, and showed reversal of gene expression patterns associated with Alzheimer's and cataracts. Since long-term epidemiologic data doesn't yet exist, Dr. Dawn follows up on last week's vaping question by exploring cancer mechanisms. Vaping aerosols impair DNA repair fidelity while triggering IL-6, IL-8, and TNF-alpha secretion. Nicotine-derived nitrosamines, reactive carbonyls (formaldehyde, acetaldehyde, acrolein) are generated when propylene glycol and vegetable glycerin are heated. Upregulated cytochrome P450 enzymes convert precarcinogens like benzopyrene into carcinogens. Mice exposed for 54 weeks developed lung adenocarcinomas in 22% and precancerous bladder hyperplasia in 57%, with markers matching those show predict lung cancer years before diagnosis. The Mexican Biobank—which includes over 40,000 samples from all 31 Mexican states revealed dramatic regional variation in drug-metabolism genes driven by Indigenous ancestry. In Chiapas, nearly 40% of the population carries two copies of a CYP2D6 variant reducing fentanyl metabolism, versus just 10% in Sinaloa. The SLCO1B1 variant hindering statin metabolism is found in over 15% of Yucatán residents., where 8 million Mexicans take statins. Dr. Dawn discusses both the promise and potential dark side of population genetic testing, including UK plans to genotype all children at birth for inborn errors of metabolism. Dr. Dawn briefly revisits the recent Indian study showing conch-shell blowing reduces sleep apnea by 34%, comparing it to earlier didgeridoo research, both of which strengthen airway muscles through forced-blowing exercises. A caller from Capitola recovering from non-Hodgkin's lymphoma near the L5 nerve asks about Japanese Kampo medicine formulas (Goshajinkigan, Yokukansan) for post-treatment nerve pain. Dr. Dawn suggests the pain likely originates from scar tissue tethering the nerve, and recommends consulting the Oriental Medicine Doctor program at Five Branches in Santa Cruz where faculty can advise on herbal formulas that trace back thousands of years through cultural exchange between China and Japan. Dr. Dawn explains Lp(a):lipoprotein(a), a small protein string attached to LDL particles that promotes clumping and clotting, is a genetically-determined coronary artery disease and stroke risk factor invisible to standard lipid panels. Levels of 250 particles double coronary risk and 350 particles triple it. Less than 75 is normal. Two new pharmaceutical strategies are in development to reduce Lp(a) : antisense oligonucleotides (single-stranded RNA that recruits RNase H to cleave target mRNA) and small interfering RNA (double-stranded RNA that triggers destruction of matching mRNA). Pelacarsen, a monthly injection in Phase 3 trials, reduces Lp(a) by 80%. These gene-silencing platforms open therapeutic possibilities for previously undruggable orphan diseases. Vitamin K2 is produced in the gut microbiome. MK-4 is most common in humans. Dr. Dawn recommends MK7 for stabilizing coronary calcium plaques and directing calcium into bone. A study of hepatitis B and C patients found MK4 to be protective in hepatocellular carcinoma. HCC developed in 2 of 21 MK-4-treated patients versus 9 of 19 controls, with a risk ratio of 0.2. MK-4 activates protein kinase A in vitro, inhibits HCC invasiveness, and restores apoptosis signaling that cancer cells normally block. Dr. Dawn recommends a couple milligrams of MK-4 daily for anyone with cirrhosis or prior hepatitis B or C infection.

Do your migraines seem to flare up as temperatures rise? Summer heat can place unique stress on the migraine brain, often triggering symptoms long before the pain begins.In this episode of Migraine Heroes Podcast, host Diane Ducarme explains how heat, dehydration, and sudden temperature shifts can impact migraine sufferers differently—and what you can do to stay one step ahead.You'll discover: ☀️ Five early clues that summer heat may be contributing to your migraine attacks ☀️ Why hot weather, fluid loss, and temperature fluctuations can affect the migraine brain so strongly ☀️ Simple ways to protect yourself from heat-related migraines and enjoy the season with greater confidenceUnderstanding your body's early signals can help you take action before a migraine fully develops. This episode offers practical insights to help you navigate warmer months with fewer disruptions and more peace of mind.

Dr. Martha Muñoz is an Assistant Professor in the Department of Ecology and Evolutionary Biology at Yale University. Martha is an evolutionary biologist who is working to better understand how and why evolution proceeds unevenly across the tree of life. Some features and branches of organisms evolve really quickly, while others remain inert or nearly inert for millions of years. Martha's research is uncovering the mechanisms underlying this phenomenon, and she has discovered that behavior is a key architect of evolution. For Martha, nature is a wonderful source of peace and inspiration for her research. When she's not working, she enjoys exploring the outdoors, hiking, seeing amazing views, and observing wildlife. She also spends her free time reading, going to museums, and visiting her family in New York City. She received her B.A. in biology from Boston University. Afterwards, Martha worked as a Fulbright Research Scholar at the National Museum of Natural Sciences in Madrid, Spain. She was awarded her Ph.D. in Organismic & Evolutionary Biology from Harvard University. Next, Martha conducted postdoctoral research in the Research School of Biology at The Australian National University and subsequently the Department of Biology at Duke University. Prior to accepting her current position at Yale University, Martha served on the faculty in the Department of Biological Sciences at Virginia Tech. Martha has received numerous awards and honors, including the Boston University Department of Biology's Distinguished Alumni 'Rising Star' Award, and a Young Investigator Award from the American Society of Naturalists. She was also named a 'Scientist to Watch' by The Scientist Magazine in 2019. In our interview, Martha shares more about her life and science.

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In this episode, my guest is Dr. Glen Jeffery, PhD, a professor of neuroscience at University College London's Institute of Ophthalmology and a leading expert on how light interacts with mitochondria to shape health and aging. Today, he discusses how red and near-infrared light penetrate deep into the body and improve mitochondrial function and overall health. We also discuss how detrimental modern indoor life has become and why expensive red light panels are likely unnecessary and possibly harmful.By the end, you'll understand sunlight as a biological input your body evolved to depend on and the low-cost, practical steps you can take to get more of it.FULL SHOW NOTES HERE: https://l1nk.dev/bjuu235 Sponsor: Shadowmap  https://app.shadowmap.org/?ref=jonathan&discount=JONATHANJ Code: JONATHANJ   Sponsor: Ra Opticshttps://www.raoptics.com/JONATHANJ Code: JONATHANJ About this guest:Academic Profile: https://profiles.ucl.ac.uk/7465 Google Scholar: https://scholar.google.com/citations?user=UYlObKkAAAAJ&hl=en LinkedIn: https://www.linkedin.com/in/glen-jeffery-441a2b1b/ Timestamps:00:16 Intro02:46 Dr. Glen Jeffery03:14 Love for Science, Undergraduate04:24 Tiina Karu, Photobiomodulation Origins, Mechanisms 06:14 Mechanisms, Cytochrome C Oxydase, Nanowater, Electron Flow10:56 Cytochrome C Oxydase, Extra-Pineal Melatonin, Oxidative Stress12:45 Gerald Pollack, Exclusion Zone (EZ) Water13:45 Red/IR Light Passes Through the Human Body; Optics18:09 Red Light On Fruit Flies; Lifespan, ATP Production21:15 Human Epidemiology; Sunlight, Lifespan, All-Cause Mortality22:35 Sponsor: Shadowmap23:30 Features and Benefits of Shadow Map25:02 Incandescents, lifespan, and more25:02 Incandescent Light Produces the Oldest Flies; Broad Band IR on Lifespan25:48 Incandescent Light Bulbs, Vision 28:19 Evolutionarily Conserved Mitochondria29:03 Long-Wavelength Light & Blood Glucose; Mitochondria32:50 Unpublished CGM Data; Long-Wavelength Light & Blood Glucose36:57 Are Red Light Panels Harmful?; Light Intensities, Precautions, Mitigations43:56 Why Do We See Beneficial Effects From Long-Wavelength Therapy? 46:43 Short-Wavelength Blue Light, Mitochondria, Mechanism49:08 The Built Environment, Actionable Steps 52:24 Sponsor: Ra Optics54:24 Flicker55:24 Retinal Health, Blue Light, Red/IR Light59:09 Clinical Trial for Mitochondrial Disease; Ptosis, Red Light01:02:31 Biophotons, Mitochondrial Communication, Red/NIR on Biophotons 01:13:54 Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Social Media, Substack Newsletter

Please visit answersincme.com/MRQ860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Alexandra K. Golant, MD; Peter Lio, MD, FAAD; and Lakshi Aldredge, MSN, ANP-BC, DCNP, FAANP. In this activity, experts in dermatology discuss the OX40L pathway and its potential role in the treatment of moderate-to-severe atopic dermatitis. Upon completion of this activity, participants should be better able to: Identify the rationale for targeting the OX40/OX40 ligand (OX40L) pathway in the treatment of moderate-to-severe atopic dermatitis (AD); Assess the evidence on efficacy outcomes and safety profiles of the emerging OX40/OX40L inhibitors in AD, including quality of life (QoL) impact; Integrate QoL assessments into shared decision-making with patients who have moderate or severe AD; and Outline strategies for enhancing the multidisciplinary management of moderate-to-severe AD.

Please visit answersincme.com/MRQ860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Alexandra K. Golant, MD; Peter Lio, MD, FAAD; and Lakshi Aldredge, MSN, ANP-BC, DCNP, FAANP. In this activity, experts in dermatology discuss the OX40L pathway and its potential role in the treatment of moderate-to-severe atopic dermatitis. Upon completion of this activity, participants should be better able to: Identify the rationale for targeting the OX40/OX40 ligand (OX40L) pathway in the treatment of moderate-to-severe atopic dermatitis (AD); Assess the evidence on efficacy outcomes and safety profiles of the emerging OX40/OX40L inhibitors in AD, including quality of life (QoL) impact; Integrate QoL assessments into shared decision-making with patients who have moderate or severe AD; and Outline strategies for enhancing the multidisciplinary management of moderate-to-severe AD.

Please visit answersincme.com/MRQ860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Alexandra K. Golant, MD; Peter Lio, MD, FAAD; and Lakshi Aldredge, MSN, ANP-BC, DCNP, FAANP. In this activity, experts in dermatology discuss the OX40L pathway and its potential role in the treatment of moderate-to-severe atopic dermatitis. Upon completion of this activity, participants should be better able to: Identify the rationale for targeting the OX40/OX40 ligand (OX40L) pathway in the treatment of moderate-to-severe atopic dermatitis (AD); Assess the evidence on efficacy outcomes and safety profiles of the emerging OX40/OX40L inhibitors in AD, including quality of life (QoL) impact; Integrate QoL assessments into shared decision-making with patients who have moderate or severe AD; and Outline strategies for enhancing the multidisciplinary management of moderate-to-severe AD.

Psychopharmacology is one of the most heavily tested and clinically consequential domains in professional psychology, covering everything from the neurochemical mechanisms behind antidepressants, antipsychotics, mood stabilizers, and anxiolytics to the pharmacokinetic principles that determine how drugs are absorbed, distributed, metabolized, and eliminated in ways that directly affect treatment outcomes and patient safety. This lecture-style episode breaks down the major drug classes tested on the EPPP and encountered in integrated care settings, including SSRIs, SNRIs, tricyclics, MAOIs, first and second generation antipsychotics, benzodiazepines, and lithium, covering their mechanisms, therapeutic windows, side effect profiles, and the clinical decision-making frameworks psychologists need to consult competently with prescribing professionals. Whether you are preparing for licensure, refreshing your pharmacology knowledge for supervision or consultation, or building the scientific foundation you need to practice in an era of increasingly integrated behavioral health care, this episode delivers the core content in a focused, high-yield format designed to make complex neuroscience and pharmacology accessible and retainable.

Kennst du das Gefühl, völlig erschöpft zu sein – und trotzdem nicht abschalten zu können? Der Körper ist müde, aber der Kopf macht Überstunden. Gedanken kreisen, der Schlaf kommt nicht und selbst kleine Dinge bringen uns aus dem Gleichgewicht. In dieser Folge sprechen Leon und Atze über Hyperarousal – einen Zustand innerer Alarmbereitschaft, den viele Menschen kennen. Warum springt unser innerer Rauchmelder manchmal schon bei Wasserdampf an? Weshalb bleiben manche Menschen ständig wachsam, gereizt oder angespannt? Und natürlich stellt sich die wichtigste Frage: Wie schaffen wir es, den Alarm wieder leiser zu drehen? Eine Folge über innere Unruhe, den Sinn unserer Alarmsysteme und die Kunst, wieder zur Ruhe zu finden. Fühlt euch gut betreut Leon & Atze Instagram: https://www.instagram.com/leonwindscheid/ https://www.instagram.com/atzeschroeder_offiziell/ Mehr zu unseren Werbepartnern findet ihr hier: https://linktr.ee/betreutesfuehlen Tickets: Atze: https://www.atzeschroeder.de/#termine Leon: https://leonwindscheid.de/tour/ Quellen: Bresser, T., Siemon, R., Rösler, L., Blanken, T. F., Sophie, & van Someren, E. J. W. (2026). Hyperarousal transdiagnostically dissected: Different dimensions characterize mood, anxiety, insomnia, posttraumatic stress and attention deficit hyperactivity disorders. eClinicalMedicine, 0(0), Article 103810. https://doi.org/10.1016/j.eclinm.2026.103810 Kendall, B. Tired yet wired. Beth Kendall. https://www.bethkendall.com/blog/tired-yet-wired Kühnel-Pfetzing, A. (2025). Stress und Hyperarousal. In H. Peter, T. Penzel, J. H. Peter, & J. G. Peter (Eds.), Enzyklopädie der Schlafmedizin. Springer. https://doi.org/10.1007/978-3-662-65186-5_212 Mastroianni, A. So you wanna de-bog yourself. Experimental History. https://www.experimental-history.com/p/so-you-wanna-de-bog-yourself McLaughlin, K. A., & Lambert, H. K. (2017). Child trauma exposure and psychopathology: Mechanisms of risk and resilience. Current Opinion in Psychology, 14, 29–34. https://doi.org/10.1016/j.copsyc.2016.10.004 Nesse, R. M. (2005). Natural selection and the regulation of defenses: A signal detection analysis of the smoke detector principle. Evolution and Human Behavior, 26(1), 88–105. https://doi.org/10.1016/j.evolhumbehav.2004.08.002 Psychology Today. (2026, January). How to stop worrying about things you can't control. https://www.psychologytoday.com/us/blog/hack-your-anxiety/202601/how-to-stop-worrying-about-things-you-cant-control Reddit. (2025). What does hypervigilance feel like to you? r/CPTSD. https://www.reddit.com/r/CPTSD/comments/1mqzkrc/what_does_hypervigilance_feel_like_to_you/ Riemann, D., Spiegelhalder, K., Feige, B., Voderholzer, U., Berger, M., Perlis, M., & Nissen, C. (2010). The hyperarousal model of insomnia: A review of the concept and its evidence. Sleep Medicine Reviews, 14(1), 19–31. https://doi.org/10.1016/j.smrv.2009.04.002 Reaktion: Julia Ditzer Produktion: Murmel Productions

In this episode, Joe and Austin explore the neuroscience of anxiety, the role of supplements, and practical strategies for managing anxiety through neuroplasticity and acceptance.Chapters00:00 Introduction and Personal Reflections02:02 Understanding Anxiety and Supplementation06:00 Neuroplasticity and Its Role in Anxiety11:47 The Mechanisms of Exposure Therapy18:00 Practical Strategies for Managing Anxiety23:57 The Role of Acceptance in Anxiety Management31:18 Embracing Anxiety as a Tool for Growth34:47 Understanding Anxiety: Normal vs. Disorder38:23 The Role of Supplements in Managing Anxiety46:07 Awareness and Acceptance: Key to Overcoming Anxiety59:14 Gradual Exposure: The Path to Resilience

What if one of the most important health crises affecting men today wasn't being caused by aging, but by the environment we live in? In this eye-opening solo episode, Darin Olien investigates the alarming decline in testosterone levels, fertility, and reproductive health among men worldwide. Drawing on decades of research, epidemiological studies, environmental science, endocrinology, and public health data, Darin examines the growing evidence connecting endocrine-disrupting chemicals, microplastics, sleep deprivation, chronic stress, poor lifestyle habits, and environmental toxins to declining testosterone levels across generations. From BPA, phthalates, atrazine, PFAS, and microplastics to sleep quality, circadian rhythms, cholesterol metabolism, cortisol regulation, and natural testosterone-supporting strategies, this episode explores what may be one of the most underreported public health issues of our time—and what men can do to take control of their health today.     What You'll Learn Why testosterone levels have been declining for decades The startling research on global sperm count decline How endocrine-disrupting chemicals interfere with hormone production Why BPA and phthalates may disrupt testosterone synthesis The role of atrazine, PFAS, and environmental toxins How chronic stress diverts resources away from testosterone production Why sleep may be the most important testosterone intervention The connection between cholesterol and hormone production How microplastics are being found throughout the human body The surprising relationship between statins and testosterone levels Natural lifestyle strategies that support healthy hormone production Practical steps to reduce environmental exposure and improve health     Chapters 00:00:00 – Welcome to SuperLife 00:00:33 – Sponsor: Fatty15 and cellular health 00:04:17 – The testosterone collapse explained 00:04:51 – Testosterone levels have been declining for decades 00:06:03 – Global sperm count decline and accelerating trends 00:07:02 – Why treating symptoms misses the root cause 00:07:27 – The hidden public health crisis 00:08:03 – Why low testosterone isn't just about aging 00:09:12 – Why hormone health affects longevity 00:09:53 – Low testosterone and increased mortality risk 00:10:35 – Testosterone's role in metabolism and cardiovascular health 00:11:27 – Endocrine-disrupting chemicals and hormone disruption 00:12:44 – BPA and its effects on testosterone production 00:13:59 – Phthalates and their impact on hormone pathways 00:16:00 – Glyphosate, atrazine, and pesticide exposure 00:17:07 – PFAS and reproductive health concerns 00:17:55 – Environmental toxins and population-wide effects 00:18:11 – Sponsor: Shakeology 00:20:02 – Cholesterol and hormone production 00:20:53 – Chronic stress and cortisol dominance 00:21:45 – Actionable solutions begin 00:21:56 – Why sleep is essential for testosterone production 00:23:07 – How sleep deprivation rapidly lowers testosterone 00:23:21 – Light pollution and circadian disruption 00:23:41 – Foods and nutrients needed for hormone health 00:24:23 – Microplastics and testicular tissue 00:24:53 – Statins and unintended hormonal consequences 00:25:39 – A practical testosterone sovereignty protocol 00:25:48 – Water filtration and reducing toxic exposure 00:26:13 – Eliminating plastics and fragrance chemicals 00:26:35 – Why organic food matters 00:26:45 – Sunlight and vitamin D 00:27:05 – Magnesium, omega-3s, and iodine 00:27:26 – Pine pollen and natural androgen support 00:28:01 – Tongkat Ali and ashwagandha 00:28:48 – Strength training and lifestyle interventions 00:29:10 – Habits that naturally support testosterone 00:29:27 – Darin's approach to healthy aging 00:29:37 – Plants, herbs, and common sense 00:29:51 – Reclaiming your health and sovereignty 00:30:00 – Final thoughts and closing message     Thank You to Our Sponsors Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Shakeology: Get 15% off with code DARINO1BODI at Shakeology.com.     Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only $7.49/month at https://patreon.com/darinolien     Find More from Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness     Key Takeaway "The testosterone crisis may be about far more than aging. It may be a reflection of the modern environment itself—one increasingly saturated with endocrine-disrupting chemicals, chronic stress, poor sleep, circadian disruption, and toxic exposures. While many of these forces feel outside our control, the encouraging reality is that many of the most powerful interventions remain accessible: improving sleep, reducing toxic load, eating whole foods, getting sunlight, managing stress, exercising regularly, and reclaiming responsibility for our health. The goal isn't fear. The goal is awareness—and action."     Bibliography/Sources: The Decline — Primary Research Levine, H., Jørgensen, N., Martino-Andrade, A., et al. (2022). Temporal trends in sperm count: A systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries. Human Reproduction Update, 29(2), 157–176. https://doi.org/10.1093/humupd/dmac035 Lokeshwar, S. D., Patel, P., Fantus, R. J., et al. (2021). Decline in testosterone levels in men aged 15–40: Results from the National Health and Nutrition Examination Survey (NHANES), 1999–2016. World Journal of Urology, 39(2), 447–452. https://doi.org/10.1007/s00345-020-03227-1 Spital Clinic. (2026, March). Declining testosterone levels by generation. https://www.spitalclinic.com Travison, T. G., Araujo, A. B., O'Donnell, A. B., Kupelian, V., & McKinlay, J. B. (2007). A population-level decline in serum testosterone levels in American men. The Journal of Clinical Endocrinology & Metabolism, 92(1), 196–202. https://doi.org/10.1210/jc.2006-1375 Low Testosterone — Mortality & Disease Risk Muraleedharan, V., Marsh, H., Kapoor, D., Channer, K. S., & Jones, T. H. (2013). Testosterone deficiency is associated with increased risk of mortality and testosterone replacement improves survival in men with type 2 diabetes. European Journal of Endocrinology, 169(6), 725–733. https://doi.org/10.1530/EJE-13-0321 Shores, M. M., et al. (2006). Low testosterone associated with increased all-cause and cardiovascular mortality. Archives of Internal Medicine, 166(15), 1660–1665. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/410754 Yeap, B. B., Marriott, R. J., Dwivedi, G., et al. (2024). Associations of testosterone and related hormones with all-cause and cardiovascular mortality and incident cardiovascular disease in men. Annals of Internal Medicine. https://doi.org/10.7326/M23-2781 Endocrine Disrupting Chemicals Associations between endocrine-disrupting chemical exposure and fertility outcomes: A decade of human epidemiological evidence. (2024). PubMed Central (PMC12299029). https://pmc.ncbi.nlm.nih.gov/articles/PMC12299029/ Hayes, T. B., Haston, K., Tsui, M., et al. (2002). Herbicides: Feminization of male frogs in the wild. Nature, 419, 895–896. https://doi.org/10.1038/419895a Mechanisms of testicular disruption from exposure to BPA and phthalates. (2020). Journal of Clinical Medicine, 9(2), 471. https://pmc.ncbi.nlm.nih.gov/articles/PMC7074154/ Meeker, J. D., Calafat, A. M., & Hauser, R. (2014). Urinary phthalate metabolites and their biotransformation products: Predictors and temporal variability among men and women. Journal of Exposure Science & Environmental Epidemiology. https://www.sciencedaily.com/releases/2014/08/140814124330.htm Zhao, Q., et al. (2023). Male reproductive toxicity of microplastics: Head and tail of the sperm. Science of the Total Environment, 872, 162181. https://doi.org/10.1016/j.scitotenv.2023.162181 Zhong, B., et al. (2024). Mixed EDC exposure associated with reductions in testosterone and free androgen index. Scientific Reports. https://doi.org/10.1038/s41598-024-76972-z Cortisol, Stress & the HPG Axis Bielohuby, M., et al. (2012). Swiss military cadets prolonged stress study. Psychoneuroendocrinology. Preprints.org. (2025). Sleep deprivation: A modifiable cause. https://doi.org/10.20944/preprints202505.0580.v1 SiPhox Health. (n.d.). Summary of Journal of Clinical Endocrinology & Metabolism data. https://www.siphoxhealth.com Viau, V. (2002). Functional cross-talk between the hypothalamic-pituitary-gonadal and -adrenal axes. Journal of Neuroendocrinology, 14(6), 506–513. https://doi.org/10.1046/j.1365-2826.2002.00798.x Sleep & Testosterone Leproult, R., & Van Cauter, E. (2011). Effect of 1 week of sleep restriction on testosterone levels in young healthy men. JAMA, 305(21), 2173–2174. https://jamanetwork.com/journals/jama/fullarticle/1029127 Reiter, R. J., et al. (2021). Melatonin and male reproductive health: Relationship to oxidative stress, mitochondrial function, and Leydig cell protection. Endocrine. Tan, D. X., Hardeland, R., Manchester, L. C., et al. (2023). Melatonin as a pleiotropic antioxidant hormone. Journal of Pineal Research. Nutrition — Zinc, Vitamin D, Cholesterol Corona, G., et al. (2010). Statin therapy and testosterone levels in men: A systematic review. The Journal of Sexual Medicine. Daniell, H. W. (2002). Hypogonadism in men consuming sustained-action oral opioids. The Journal of Pain, 3(5), 377–384. https://doi.org/10.1054/jpai.2002.126790 Pilz, S., Frisch, S., Koertke, H., et al. (2011). Effect of vitamin D supplementation on testosterone levels in men. Hormone and Metabolic Research, 43(3), 223–225. https://doi.org/10.1055/s-0030-1269854 Prasad, A. S., Mantzoros, C. S., Beck, F. W., Hess, J. W., & Brewer, G. J. (1996). Zinc status and serum testosterone levels of healthy adults. Nutrition, 12(5), 344–348. https://doi.org/10.1016/S0899-9007(96)80058-X Natural Testosterone Support — Botanical Evidence Pine pollen impacts testosterone-related symptoms in men. (2024). ACMCR Case Reports, 14(5), 1–9. Chinnappan, S. M., George, A., et al. (2021). Effect of Eurycoma longifolia standardised extract Physta on testosterone levels in ageing males: A randomised, double-blind, placebo-controlled multicentre study. Food & Nutrition Research, 65. https://doi.org/10.29219/fnr.v65.5647 Lazarev, A., & Bezuglov, E. (2021). Testosterone boosters intake in athletes: Current evidence and further directions. Endocrines, 2(2), 109–120. https://doi.org/10.3390/endocrines2020011 Leisegang, K., et al. (2022). Eurycoma longifolia (Tongkat Ali) improves serum total testosterone in men. Food & Nutrition Research. https://pubmed.ncbi.nlm.nih.gov/36013514/ Leitão, A. E., et al. (2021). 6-month double-blind RCT: Eurycoma longifolia 200mg + concurrent training. Maturitas. https://doi.org/10.1016/j.maturitas.2020.10.005 Lopresti, A. L., Smith, S. J., et al. (2019). An investigation into the stress-relieving and pharmacological actions of an ashwagandha extract. Medicine, 98(37), e17186. https://doi.org/10.1097/MD.0000000000017186 Pandit, S., Biswas, S., Jana, U., De, R. K., Mukhopadhyay, S. C., & Biswas, T. K. (2016). Clinical evaluation of purified shilajit on testosterone levels in healthy volunteers. Andrologia, 48(5), 570–575. https://doi.org/10.1111/and.12482 Saden-Krehula, M., Tajic, M., & Kolbah, D. (1971). Testosterone, epitestosterone and androstenedione in the pollen of Scotch pine Pinus sylvestris L. Experientia, 27(1), 108–109. https://doi.org/10.1007/BF02137731 Wankhede, S., Langade, D., Joshi, K., et al. (2015). Examining the effect of Withania somnifera supplementation on muscle strength and recovery: A randomized controlled trial. Journal of the International Society of Sports Nutrition, 12, 43. https://doi.org/10.1186/s12970-015-0104-9

Episode 97: Cole Smith - Games that Combine 2 Mechanisms well - Top 5 Area Control Games - A Frame Job & Good FoodCanadian board game and graphic designer, Cole Smith, joins me to talk about his current published games, games that combine 2 mechanisms well, and his favorite mechanism, area control, games.00:00:00 Intro00:00:21 Get to Know Cole Smith and his gamesTanuki Sauros 3 Magi 00:05:58 The Journey of Game Design00:08:23 Cole's Favorite Mechanism or Game that inspires him00:14:42 Games that Blend 2 Well-Known Mechanics WellLost Ruins or ArnakDune ImperiumEndless Winter: PaleoamericansPatchworkCascadia and other Flatout line of gamesSaurosRumble NationRadlands 7 Wonders DuelSagrada Nokosu diceKing of TokyoThe Lord of the Rings: The Fellowship of the Ring - Trick Taking GameIliadTag TeamArcs00:33:32 Top 5 Area Control Games00:37:57 The King is Dead: Second Edition00:40:18 Rumble Nation00:41:46 Waddle00:44:35 Ankh: Gods of Egypt00:47:25 Marrakech00:50:50 Rumble Nation (Overlap)00:51:09 Sunrise Lane00:54:27 Scythe00:58:45 Foundations of Rome01:03:16 Root01:07:26 Patrician01:10:29 Honorable Mentions01:10:40 Big Boss01:12:59 Shackleton Base: A Journey to the Moon01:15:01 Ahoy01:16:02 Moment of Positivity01:20:09 Where can you find Cole?BGG Designer PageInstagram @Cole_Designs_Games01:21:24 Outro(Please note that these time stamps might not be accurate due to the use of dynamic ads.)You can flip your game night by picking up DNUP.https://www.dnup.game/en/Web: https://boardgamegeek.com/YouTube: https://www.youtube.com/@boardgamegeekTwitter: https://twitter.com/BoardGameGeekEmail: podcast@boardgamegeek.com

The episode opens with a welcome to the podcast and introductions to the panelists. It highlights their diverse expertise in mineral metabolism, applied nutrition, and industry insights. (00:00 – 02:38) The discussion begins with a deep dive into the mechanisms of mineral absorption, focusing on epithelial barriers and transporters. The panel discusses how minerals like magnesium are absorbed across the rumen wall. Moreover, they explore how antagonists interfere with absorption and introduce the concept of measuring bioavailability under field conditions. (04:35 – 10:13) From there, the conversation shifts to practical dairy nutrition strategies, including how to manage macro minerals and antagonists within the diet. The panel discusses the importance of water quality and alternative magnesium sources. Additionally, they share effective calcium strategies for supporting fresh cows and reducing metabolic challenges. (11:36 – 16:48) The panel then explores mineral interactions and balance, including the concept of mineral homeostasis and the role of skeletal calcium reserves. They challenge traditional thinking around calcium-to-phosphorus ratios. Furthermore, they examine key interactions between potassium, magnesium, and sodium that can impact absorption and overall animal health. (18:59 – 24:42) As the episode continues, the discussion turns to the future of agricultural research, including the growing role of genomics in shaping nutrient requirements. The panel also addresses ongoing challenges in funding and education. Additionally, they discuss the broader influence of policy and corporate investment on the direction of scientific research. (26:03 – 32:43) Attention then shifts to diagnostics and emerging tools, where the panel discusses biomarkers and enzyme-based approaches for tracking bioavailability. They also emphasize the importance of proper blood sampling timing. Additional topics include phosphorus binders, zeolite-based diets, and unanswered questions around the evolutionary role of magnesium. (33:48 – 38:34) The episode concludes with a focus on holistic mineral management, emphasizing the importance of integrating scientific understanding into practical feeding decisions. The panel shares final insights and key takeaways for improving mineral nutrition programs. In summary, they also support long-term dairy cow performance. (41:20 – 42:38) Please subscribe and share with your industry friends. Invite more people to join us at the Real Science Exchange virtual pub table. Please be sure to register for our upcoming Real Science Lecture Series webinars. Finally, if you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription. Then, email a picture to anh.marketing@balchem.com. Include your size and mailing address. As a result, we'll mail you a shirt.

Dr. Kassam explains how hormones, IGF-1, nitrates, and saturated fat in dairy and meat promote cancer growth and DNA damage. #CancerRiskFactors #DairyAndCancer #MeatAndCancer #NutritionMechanisms

BUFFALO, NY — June 16, 2026 — A new #research paper was #published in Volume 18 of Aging on May 22, 2026, titled “Systemic cancer risk profile in neovascular age-related macular degeneration: insights into shared aging-related mechanisms from a nationwide population-based study.” The study was led by first author Hyeong Min Kim and corresponding author Hyewon Chung from Konkuk University College of Medicine and Konkuk University Medical Center in Seoul, Republic of Korea. Neovascular age-related macular degeneration (nAMD) is one of the leading causes of severe vision loss in older adults. Although the disease primarily affects the retina, researchers increasingly recognize that it may reflect broader biological processes associated with aging, including chronic inflammation, vascular dysfunction, and immune dysregulation. These same mechanisms have also been implicated in the development of several cancers, raising questions about whether the two conditions may be biologically connected. To explore this possibility, investigators analyzed data from the Korean National Health Insurance Service, one of the world's largest population-based healthcare databases. The study included 334,091 individuals aged 50 years and older, including 83,742 patients with nAMD and 250,349 matched controls without the disease. Participants were followed for up to 10 years, allowing researchers to evaluate both overall cancer incidence and risks for specific cancer types. The analysis revealed that individuals with nAMD had a modest but statistically significant increase in overall cancer risk compared with matched controls. However, the increased risk was not observed across all cancers. Instead, patients with nAMD showed elevated risks for several specific malignancies, including thyroid, kidney, pancreatic, lung, bladder, and prostate cancers, while no significant associations were found for many other cancer types. Full press release - https://aging-us.net/2026/06/16/common-aging-mechanisms-may-link-vision-loss-disorder-to-increased-risk-of-certain-cancers/ DOI - https://doi.org/10.18632/aging.206383 Corresponding author - Hyewon Chung - hchung@kuh.ac.kr Abstract video - https://www.youtube.com/watch?v=hViOqGLYr1Y Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206383 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, neovascular age-related macular degeneration, cancer, population cohort, polygenic risk, shared susceptibility To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Die fünf langweiligsten Ernährungstipps der Welt machen 95 % Deiner Ergebnisse aus. Und fast jeder übersieht sie – so wie den Gorilla, der in einem verblüffenden Experiment mitten durchs Bild läuft und sich auf die Brust trommelt.Wenn Du dieses Jahr nur eine Folge über Ernährung hörst, dann bitte diese. Du erfährst, welche fünf Ernährungsgewohnheiten Dir einen „unfairen“ Fitnessvorteil verschaffen – und wie Du sie entspannt in 10 Wochen umsetzt. Ohne dabei auf das zu verzichten, was Du liebst.____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.

Welcome to episode #1040 of Thinking With Mitch Joel (formerly Six Pixels of Separation). Long before artificial intelligence became the dominant business conversation, Sangeet Paul Choudary was helping leaders understand another profound shift in economic power: the rise of platforms. As the co-author of Platform Revolution, founder of Platform Thinking Labs, advisor to global corporations and governments, and a respected thinkers on digital business models, Sangeet has spent years studying how technology changes the sources of competitive advantage and reshapes entire industries. His latest book, Reshuffle - Who Wins When AI Restacks The Knowledge Economy, extends that work into the age of artificial intelligence, exploring what happens when the expertise, judgment and know-how that once lived inside individuals and organizations increasingly migrates into software systems. In this conversation, Sangeet explains why AI represents far more than a productivity upgrade. He argues that every major technological shift changes what is scarce, and when scarcity changes, value moves with it. Drawing on examples ranging from Kodak and Netflix to cloud computing, software platforms and global supply chains, he explores why some organizations adapt while others become trapped by the assumptions that made them successful in the first place. The discussion also examines the changing nature of economic power, the growing importance of digital sovereignty, the future of knowledge work, and the risks of assuming that today's business models will survive tomorrow's technological realities. Throughout the conversation, Sangeet offers a framework for understanding not just what AI can do, but how leaders can rethink their organizations, industries and careers when the foundations of value creation are being rewritten in real time. Enjoy the conversation… Running time: 1:00:47. Hello from beautiful Montreal. Listen and subscribe over at Apple Podcasts. Listen and subscribe over at Spotify. Please visit and leave comments on the blog - Thinking With Mitch Joel. Feel free to connect to me directly on LinkedIn. Check out ThinkersOne. Here is my conversation with Sangeet Paul Choudary. Reshuffle - Who Wins When AI Restacks The Knowledge Economy. Platform Thinking Labs. Platform Revolution. Follow Sangeet on X. Follow Sangeet on LinkedIn. Chapters: (00:00) - Introduction to Sangeet Chaudhary and Reshuffle. (02:51) - The Impact of Technological Shifts on Value Creation. (05:51) - Understanding Architectural Constraints in Business. (09:07) - The Role of Supply Chain in Innovation. (12:10) - AI's Influence on Software and Business Models. (14:56) - Navigating Uncertainty in AI Adoption. (18:04) - The Future of Economic Power and Sovereignty. (21:00) - Cultural Shifts in Power Dynamics. (23:53) - The Mechanisms of Change in AI and Business. (26:52) - The Balance of Sovereignty and Dominance. (29:46) - The Future of Work in an AI-Driven Economy. (32:44) - The Broader Implications of AI on Society. (36:40) - Conclusion and Reflections on Reshuffle.

Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition. Guest Links Dr. Milo Wolf's Links: Website/Coaching: Wolf Coaching App: MyoAdapt YouTube: Dr. Milo Wolf Instagram: @wolfcoach_ Timestamps 00:00 Intro and why warmups matter 00:46 Why warmups may be overrated for hypertrophy 03:21 General vs specific warmups and static vs dynamic stretching 04:41 Static stretching and short-term performance tradeoffs 07:25 Stretching and injury-prevention evidence 10:08 FIFA 11, strength training, plyometrics, and multi-part warmups 11:42 Why plyometrics can build resilience 15:55 Mechanisms: temperature, oxygen uptake, psychology, and neural readiness 18:16 Sports-team warmups, coaching logistics, and specificity 38:29 Nick's real warmup routine and Milo's reaction 49:20 Milo's default warmup recommendation 53:07 Pain, injury, and adjusting the approach  

In Part 3 of Detox in a Toxic World, we take a closer look at what “detox” actually means and how the body is already doing it every single day. This episode breaks down the body's major detox and elimination pathways, including the liver, gut, kidneys, lungs, skin, lymphatic system, and glymphatic system, and explains how these beautifully coordinated processes help clear hormones, waste products, and environmental compounds.We also walk through practical, evidence-based ways to support these natural detox mechanisms, including nutrition, hydration, movement, sweating, lymphatic support, sleep, mind-body medicine, and time in nature.Companion Guide: drmaryellawood.com/guides 

Message me!In Episode 1, we open the doors to the Asylum, explore what this space is really about, and begin with a grounding lesson on presence, breath, and learning to meet yourself exactly where you are.Message me!Read the Research Blog:https://carifavole.wordpress.com/2026/06/06/episode-1-welcome-to-the-asylum/EPISODE RESOURCES & REFERENCES:[ ▶︎ ] Heart Activation Breathing Method | ASMR Mindfulness Meditation:https://youtu.be/oAnWikPJLnY?si=FK7wAv67NOOoF1IF- American Psychological Association. (2020). Stress and coping. https://www.apa.org/topics/stress-Brown, B. (2006). Shame resilience theory: A grounded theory study on women and shame. Families in Society, 87(1), 43–52.-Compas, B. E., Jaser, S. S., Bettis, A. H., et al. (2017). Coping, emotion regulation, and psychopathology: Mechanisms of risk and resilience. Journal of Child Psychology and Psychiatry, 58(2), 125–150.- Granic, I., Lobel, A., & Engels, R. C. M. E. (2014). The benefits of playing video games. American Psychologist, 69(1), 66–78.-Kowert, R., & Quandt, T. (2020). Video games and social competence. Routledge.-Mar, R. A., & Oatley, K. (2008). The function of fiction is the abstraction and simulation of social experience. Perspectives on Psychological Science, 3(3), 173–192.- Neff, K. D. (2011). Self-compassion: The proven power of being kind to yourself. HarperCollins.- World Health Organization. (2014). Social determinants of mental health. https://www.who.int- World Health Organization. (2022). Guidance on community mental health services. https://www.who.int•☽────✧˖°˖☆

Join us for "Between the Lines", an online series that brings the mindfulness community together to explore the books, papers, and other resources that have shaped the mindfulness field — alongside the authors and thinkers who created them.   In this insightful session, Zindel Segal responds to community questions from our book club–style discussion of his keynote, "Interoception, Body Awareness and Mechanisms of Change".   Our "Between the Lines" events will take place monthly over 2026. View more of our upcoming mindfulness courses and events ▶️ https://oxfordmindfulness.org/courses-events   Oxford Mindfulness is a not-for-profit organisation helping people achieve greater well-being and improved mental health through research-based mindfulness. Visit our website https://oxfordmindfulness.org/

The Tenpenny Files – Jeff Brown shares his account of entering Canada's political inner circle and facing alleged surveillance, interception, suppression, and institutional pressure after trying to leave. The discussion examines power, censorship, media control, sovereignty, and the invisible systems Brown believes shape perception, isolate dissenters, and threaten individual freedom in modern political life...

Jason Jay Smart is a political adviser who has lived and worked in Ukraine, Moldova, Kyrgyzstan, Kazakhstan, Russia, and Latin America. Due to his work with the democratic opposition to Vladimir Putin, Smart was made persona non grata for life by Russia in 2010. Jason is a Special Correspondent at the Kyiv Post. It's the state of US support for Ukraine that we will discuss today.----------LINKS:https://jasonjaysmart.com/ https://www.kyivpost.com/authors/5 https://americanpoliticalservices.com/https://www.facebook.com/jasonjaysmarthttps://twitter.com/officejjsmart ----------SUPPORT THE CHANNEL:https://www.buymeacoffee.com/siliconcurtainhttps://www.patreon.com/siliconcurtainhttps://www.gofundme.com/f/scaling-up-campaign-to-fight-authoritarian-disinformation----------TRUSTED CHARITIES ON THE GROUND:Car4Ukrainehttps://car4ukraine.com/en-US/campaignsDzyga's Pawhttps://dzygaspaw.com/projectsSuperhumans - Hospital for war traumashttps://superhumans.com/en/UNBROKEN - Treatment. Prosthesis. Rehabilitation for Ukrainians in Ukrainehttps://unbroken.org.ua/Come Back Alivehttps://savelife.in.ua/en/Chefs For Ukraine - World Central Kitchenhttps://wck.org/relief/activation-chefs-for-ukraineUNITED24 - An initiative of President Zelenskyyhttps://u24.gov.ua/Serhiy Prytula Charity Foundationhttps://prytulafoundation.orgNGO “Herojam Slava”https://heroiamslava.org/----------PLATFORMS:Substack: https://substack.com/@siliconcurtainTwitter: https://twitter.com/CurtainSiliconLinkedin: https://www.linkedin.com/in/finkjonathan/Podcast: https://open.spotify.com/show/4thRZj6NO7y93zG11JMtqm----------

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Send us Fan MailWelcome to this brief episode on dry needling and what current research suggests may explain its pain-relieving effects. The episode clarifies why it's called “dry” needling (no medication injected) and emphasizes the importance of being able to explain why it may help patients. Dry needling is presented as working locally and systemically through four main mechanisms: local muscle and tissue effects, biomechanical and inflammatory biomarker changes, peripheral and spinal pain modulation, and supraspinal/autonomic pathways. We also discuss who this is appropriate for, and how to combine it with other techniques to help our patients get to their goals successfully.00:00 Welcome to PTs Snacks00:48 Why Dry Needling Matters01:15 What It Is and Isn't02:39 Four Mechanisms Overview03:24 Local Tissue Effects04:19 Inflammation Biomarkers05:14 Spinal Pain Modulation06:35 Autonomic Brain Pathways07:16 Who Should Avoid It07:58 Patient Education and Training08:52 Wrap Up and Next StepsNeed CEUs?Unlock unlimited online courses, live webinars, and certification-prep programs with MedBridge. You'll get thousands of accredited, evidence-based courses. Use code PTSNACKSPODCAST at checkout to save over $100. Student? Use code PTSNACKSPODCASTSTUDENTSupport the showStudying for the NPTE? Check out PT Final Exam — they've helped thousands of students pass with confidence. Use code PTSnacks at checkout for a discount.Stay Connected!Follow so you never miss an episode. Send your questions via email to ptsnackspodcast@gmail.comJoin the email list HERESupport the Show:Share the episode with someone who'd benefit.Contributing directly to the "support" link.Thanks for tuning in—your support makes this all possible!

If you enjoy this episode, we're sure you will enjoy more content like this on The Occult Rejects.  In fact, we have curated playlists on occult topics like grimoires, esoteric concepts and phenomena, occult history, analyzing true crime and cults with an occult lens, Para politics, and occultism in music. Whether you enjoy consuming your content visually or via audio, we've got you covered - and it will always be provided free of charge.  So, if you enjoy what we do and want to support our work of providing accessible, free content on various platforms, please consider making a donation to the links provided below.  Thank you and enjoy the episode!Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Cash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejectsBibliographyThe Mechanics of Magick: Singing Bowls and the Ritual Physics of ResonanceCore Singing Bowl ResearchStanhope, Jessica, and Philip Weinstein. “The Human Health Effects of Singing Bowls: A Systematic Review.” Complementary Therapies in Medicine 51 (2020): 102412. Use for the honesty frame: promising findings around mental health and cardiovascular measures, but limited evidence and need for stronger study design.Cai, Yiqing, Guo-Yan Yang, Yibo Liu, Xiang-yun Zou, Heng Yin, Xinyan Jin, Xue-han Liu, Chenlu Wang, Nicola Robinson, and Jian-Ping Liu. “Therapeutic Effects of Singing Bowls: A Systematic Review of Clinical Studies.” Integrative Medicine Research 14, no. 2 (2025): 101144. Use for the newer clinical overview. Important correction: this appears as 101144, not 101176. Good for anxiety, depression, sleep quality, cognition, autistic behavior, and EEG-related outcomes while still keeping the evidence cautious.Lin, F. W., et al. “Effects of Tibetan Singing Bowl Intervention on Psychological and Physiological Health in Adults: A Systematic Review.” 2025. Useful as another recent review angle, especially for psychological health, physiological measures, HRV, and brainwave-related discussion. Keep it secondary behind Stanhope and Cai.Landry, Jayan Marie. “Physiological and Psychological Effects of a Himalayan Singing Bowl in Meditation Practice: A Quantitative Analysis.” American Journal of Health Promotion 28, no. 5 (2014): 306–309. Use for the controlled relaxation study: 51 participants, randomized crossover design, singing bowl exposure or silence before directed relaxation.Goldsby, Tamara L., Michael E. Goldsby, Mary McWalters, and Paul J. Mills. “Effects of Singing Bowl Sound Meditation on Mood, Tension, and Well-Being: An Observational Study.” Journal of Evidence-Based Complementary & Alternative Medicine 22, no. 3 (2017): 401–406. Use for reductions in tension, anger, fatigue, depressed mood, anxiety, and stress after singing bowl meditation. Good, but frame as observational, not definitive.Rio-Alamos, Cristina, et al. “Acute Relaxation Response Induced by Tibetan Singing Bowl Sounds: A Randomized Controlled Trial.” European Journal of Investigation in Health, Psychology and Education 13, no. 2 (2023): 317–328. Use for Tibetan singing bowl treatment compared with progressive muscle relaxation and a waiting-list control in anxious nonclinical adults.Walter, Nina, et al. “Neurophysiological Effects of a Singing Bowl Massage.” Medicina 58, no. 5 (2022): 594. Use for EEG, ECG, and respiration during singing bowl massage; the authors interpret the results as a shift toward a more mindful or meditative state.Goldsby, Tamara L., et al. “Mood, Emotional, and Spiritual Well-Being Interrelationships.” Religions 13, no. 2 (2022). Useful follow-up for spiritual well-being, emotional interpretation, and how people understand sound-healing experiences.Sound, Anxiety, HRV, and Brainwave CautionMallik, Adiel, and Frank A. Russo. “The Effects of Music & Auditory Beat Stimulation on Anxiety: A Randomized Clinical Trial.” PLOS ONE 17, no. 3 (2022): e0259312. Use this carefully for the broader point that sound-based treatments can reduce somatic and cognitive state anxiety. Do not use it as proof that singing bowls automatically entrain brainwaves.Ingendoh, Ruth Maria, Ella S. Posny, and Angela Heine. “Binaural Beats to Entrain the Brain? A Systematic Review of the Effects of Binaural Beat Stimulation on Brain Oscillatory Activity, and the Implications for Psychological Research and Intervention.” PLOS ONE 18, no. 5 (2023): e0286023. Very useful caution source. Use it when warning against overclaiming “brainwave entrainment” and frequency-healing claims.Vilímek, et al. 2022. Low-frequency sound / HRV / vibroacoustic-related research. Use cautiously if you want to discuss low-frequency vibration, body sensation, and autonomic response. I'd keep this as a secondary source unless you want a dedicated paragraph on vibroacoustics.Physics, Resonance, and CymaticsTerwagne, Denis, and John W. M. Bush. “Tibetan Singing Bowls.” Nonlinearity 24, no. 8 (2011): R51–R66. Use for the physics section: wall vibrations, water-surface waves, Faraday-wave effects, droplet motion, and the visible demonstration of resonance.Jenny, Hans. Cymatics: A Study of Wave Phenomena and Vibration. Newmarket, NH: MACROmedia, 2001. Use carefully for visual sound-pattern history. Good for imagery and occult imagination, but don't overuse it as clinical proof.Rossing, Thomas D. The Science of Sound. 3rd ed. San Francisco: Addison Wesley, 2002. Useful general acoustics source for resonance, overtones, vibration, sound waves, and instrument physics.Sound Baths, Wellness Culture, and Modern RitualSobo, Elisa J. “Sound Baths, Trauma Talk, and the Wellness Paradox in the USA.” Medical Anthropology 43, no. 5 (2024): 367–382. Excellent for the modern sound-bath/wellness-culture angle, especially trauma language, nervous-system talk, ritual performance, and how providers frame sound baths.Sobo, Elisa J. “A Beginner's Guide to Sound Baths — What They Are, How to Choose a Good One and What the Research Shows.” The Conversation (2024). Useful for accessible show-note language and ethical/practical framing.Sobo, Elisa J. “Healing Vibrations.” Anthropology News 64, no. 5 (2023): 28–32, 49. Good anthropology/public-facing source for sound healing and wellness culture.Tibetan Singing Bowls, History, and Cultural CommodificationGrimes, Samuel. “Where Did ‘Tibetan' Singing Bowls Really Come From?” Tricycle (2020). Use for the contested-history section. Strong source for questioning popular origin stories around “Tibetan” singing bowls.Joffe, Ben. “Anthropology and Tibetan Buddhism / Cultural Commodification / Tibetan Mystique.” 2015. Use for the larger argument about how Tibetan/Himalayan aura gets packaged in Western spiritual markets. Good support for the “Tibet as imagined storehouse of hidden wisdom” point.Scheidegger, Daniel A. “Tibetan Ritual Music.” Use for actual Tibetan Buddhist ritual sound: bells, cymbals, long horns, drums, chant, and liturgical soundscape. This helps separate real Tibetan ritual sound from overblown modern singing-bowl mythology.Lopez, Donald S. Prisoners of Shangri-La: Tibetan Buddhism and the West. Chicago: University of Chicago Press, 1998. Excellent support for Western romanticization of Tibet.Bishop, Peter. The Myth of Shangri-La: Tibet, Travel Writing, and the Western Creation of Sacred Landscape. Berkeley: University of California Press, 1989. Very useful for the “Tibet as fantasy geography” angle.Ritual, Sound, and Religious ExperienceEliade, Mircea. Shamanism: Archaic Techniques of Ecstasy. Princeton: Princeton University Press, 1964. Use carefully. Good for altered-state technologies and ritual sound/trance, but don't treat it as the final word on shamanism.Rouget, Gilbert. Music and Trance: A Theory of the Relations Between Music and Possession. Chicago: University of Chicago Press, 1985. Excellent for sound, music, trance, possession, rhythm, and ritual performance.Becker, Judith. Deep Listeners: Music, Emotion, and Trancing. Bloomington: Indiana University Press, 2004. Strong source for deep listening, music, emotion, trance, and the body.Husserl, Edmund. On the Phenomenology of the Consciousness of Internal Time. Useful if you want to get philosophical about tone, decay, waiting, and how sound reveals time.Ihde, Don. Listening and Voice: Phenomenologies of Sound. Albany: SUNY Press, 2007. Good for sound as experience, listening, voice, and embodied perception.Placebo, Meaning Response, and Healing RitualMoerman, Daniel E. Meaning, Medicine and the “Placebo Effect.” Cambridge: Cambridge University Press, 2002. Use for “meaning response” instead of treating placebo as “fake.”Benedetti, Fabrizio. Placebo Effects: Understanding the Mechanisms in Health and Disease. Oxford: Oxford University Press, 2009. Useful for placebo mechanisms, expectation, physiology, and therapeutic context.Kaptchuk, Ted J., and Franklin G. Miller. “Placebo Effects in Medicine.” New England Journal of Medicine 373 (2015): 8–9. Good short medical source for placebo effects as real psychobiological phenomena.Csordas, Thomas J. The Sacred Self: A Cultural Phenomenology of Charismatic Healing. Berkeley: University of California Press, 1994. Useful for healing, embodiment, ritual, and religious experience.Embodied Cognition, Extended Mind, and Ritual ToolsClAlso want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. A

The South Carolina Supreme Court reversed Alex Murdaugh's murder convictions on procedural grounds — finding the trial judge misapplied the burden of proof, violated Rule 606(b) by probing jurors' mental processes, and credited testimony the court deemed inadmissible. A retrial has been ordered under significantly narrowed evidentiary parameters. The central unknown heading into that proceeding is Buster Murdaugh.Buster testified for the defense at the original trial. He has since reportedly distanced himself from Alex — minimal prison contact, a quiet marriage, and according to sources, open anger about the retrial. He has allegedly characterized his father as a "selfish old man." Jennifer Coffindaffer and retired FBI behavioral analyst Robin Dreeke examine whether the prosecution can leverage that fracture and what legal mechanisms exist to compel testimony about private conversations between father and son after the killings. Coffindaffer also identifies a structural weakness in the State's family annihilation theory: if Alex allegedly killed to eliminate exposure, the survival of Buster undermines the logic of the motive as constructed.Defense attorney and former prosecutor Eric Faddis provides the comprehensive legal breakdown. The Supreme Court ruled twelve and a half hours of financial crimes testimony was excessive and ordered sharp limitations at retrial. Faddis maps what survives — the CFO confrontation and the opposing attorney's hearing that form the motive timeline — and what gets excluded. He addresses the unresolved evidentiary challenges carried forward from the direct appeal: the firearm analysis, the blue raincoat, the gunshot residue testimony, and the iPhone demonstration. He also examines the retrial complications — Alex Murdaugh's locked-in testimony, Becky Hill's perjury conviction as a defense weapon, and the venue and jury selection challenges both sides face in a case with this level of public saturation.Join Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1Instagram https://www.instagram.com/hiddenkillerspod/Facebook https://www.facebook.com/hiddenkillerspod/Tik-Tok https://www.tiktok.com/@hiddenkillerspodX Twitter https://x.com/TrueCrimePodThis publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.#AlexMurdaugh #BusterMurdaugh #MurdaughRetrial #EricFaddis #BeckyHill #SCSupremeCourt #JenniferCoffindaffer #RobinDreeke #HiddenKillers #TrueCrime

PREVIEW for Later Today: Henry Sokolski. Henry Sokolski discusses the NPT review, warning against granting enrichment rights to Middle Eastern nations and emphasizing the need for stronger international enforcement mechanisms.

Dan Hillery is a Founding Member of True North and a macro strategist specializing in Bitcoin price modeling and derivatives.› ⁠https://x.com/hillery_dan⁠PARTNERS

The gang discusses two papers that investigate phenotypic plasticity. The first paper reviews the pathways by which phenotype can be plastic, and the second paper looks at plasticity of breeding times in urban vs rural bird populations. Meanwhile, James manages a basement, Amanda names the papers, and Curt makes allegations.   Up-Goer Five (James Edition): Today the group look at two papers that are interested in how animals change because of the type of place they live. The first paper is looking at different ways that animals can be changed, either by being changed as they grow or by changing things so that while the animal does not change right now its babies are different. The paper talks about how important the little bits that escape the brain to tell your body how to grow and what to make are and that many of the changes are caused by the different numbers of things escaping the brain because of the different places that the animal lives. The other paper is looking at small angry animals that fly and seeing when they lay small round quiet babies in different places. They look at when the small round quiet babies first appear in places that are built by people and places that are built by trees and also look at how this time has changed over several years during which it has gotten hotter. They find that most small angry animals that fly have their small round quiet babies earlier in places that are built by people, and also that as things have gotten hotter that also makes them have their small round quiet babies earlier. The further up they are though it seems like the time between having small round quiet babies in place built by people and places built by trees is not as much.   References: Seebacher, Frank, and Alexander G. Little. "Mechanisms underlying phenotypic plasticity in response to environmental change." Biological Reviews 101.2 (2026): 713-734. Cuchot, Paul, et al. "Facing rising temperatures in urban environments: the role of phenological plasticity in an urban-dwelling passerine, Parus major." Proceedings of the Royal Society B: Biological Sciences 293.2068 (2026).

There are plenty of ways to sell your high-ticket coaching offers, but not every method will work for every person. Today, Jill shares 3 sales mechanisms her clients have been using to great success. While all 3 clients tried something different, he real differentiator across all three approaches isn't the mechanism itself, but the messaging behind it, and in 2026, simply "checking the box" with a webinar or funnel is no longer enough to drive sales.   Get on the Waitlist for Strategy Lab: https://jillfitfree.com/strategy-lab-wait-list/   Catch the replay for Low Ticket Revolution! https://www.jillfitprograms.com/Low-Ticket-Revolution   Get on the waitlist for FBA: https://jillfitfree.com/fba-waitlist/     Jill is a fitness professional and business coach who effectively made the transition from training clients in person and having no time to build anything else to training clients online and actually being more successful. Today, Jill helps other coaches to do the same.   Connect with me! Instagram: @jillfit | @fitbizu Facebook: @jillfit Website: jillfit.com

Stay informed on current events, visit www.NaturalNews.com  - Backlash Against AI Data Centers (0:12) - Ethical and Legal Challenges of Data Centers (3:25) - Government and Corporate Influence on Data Center Locations (7:53) - Impact of AI Surveillance and Authoritarian Governments (10:08) - Famine and Fuel Shortages in America (12:22) - Human Migration and Economic Instability (44:47) - Cannibalism and Depopulation Techniques (1:05:30) - Economic and Social Implications of Depopulation (1:13:23) - Historical Context of Famines and Government Control (1:20:01) - Mechanisms of Creating Famines (1:23:29) - Historical Figures and Famine Preparedness (1:27:08) - Impact of Infrastructure Destruction (1:31:38) - Globalist Agendas and Human Resources (1:34:27) - Vulnerabilities of Mega Cities and Regions (1:45:42) - Grand Strategic Level and Synthetic Countries (1:47:58) - Future Vision of Global Elites (1:57:35) - Final Thoughts and Recommendations (2:02:43) Watch more independent videos at http://www.brighteon.com/channel/hrreport  ▶️ Support our mission by shopping at the Health Ranger Store - https://www.healthrangerstore.com ▶️ Check out exclusive deals and special offers at https://rangerdeals.com ▶️ Sign up for our newsletter to stay informed: https://www.naturalnews.com/Readerregistration.html Watch more exclusive videos here:

What if loneliness isn't just an emotion… but one of the most dangerous biological threats to your health? In this deeply personal and scientifically explosive solo episode, Darin opens up about something he recently realized in his own life: despite being surrounded by people, he was lonely. But what began as an emotional realization quickly became a deep dive into some of the most shocking research he's ever uncovered, showing that chronic loneliness may increase the risk of heart disease, dementia, cancer, autoimmune dysfunction, accelerated aging, and early death. From inflammatory gene expression and cortisol dysregulation to oxytocin, vulnerability, and the collapse of real human connection in the digital age, this episode reveals why loneliness may be the most overlooked "fatal convenience" of modern life, and how vulnerability may be the medicine. What You'll Learn Why loneliness is a biological crisis, not just an emotional feeling The shocking link between loneliness and heart disease, dementia, and early death Why the quality of your relationships is the #1 predictor of long-term health How loneliness activates inflammatory genes inside your body The role of cortisol, sleep disruption, and chronic stress in social isolation Why social media and "surface-level connection" are replacing real intimacy The connection between loneliness and Alzheimer's disease How oxytocin and genuine connection reduce inflammation Why vulnerability is the gateway to meaningful relationships Practical ways to create deeper connection starting today Chapters 00:00:33 – Sponsor: the truth about the exploding NAD supplement market 00:01:04 – Why supplement verification and transparency matter 00:02:17 – Opening: Darin admits something deeply personal 00:02:30 – "I realized recently… I'm lonely" 00:02:37 – The difference between being surrounded by people vs being truly known 00:03:06 – Loneliness as a biological experience, not just an emotional one 00:03:27 – The hidden risks: heart disease, dementia, cancer, early death 00:03:45 – Why this is not fringe science 00:04:13 – The most important predictor of long-term health 00:04:34 – Why relationship QUALITY matters more than quantity 00:05:06 – The global loneliness epidemic 00:05:11 – U.S. Surgeon General advisory on loneliness 00:05:39 – Loneliness declared a public health crisis 00:06:02 – 50% of Americans report measurable loneliness 00:06:22 – "A generational collapse of connection" 00:06:30 – 29% of adults have no close friends 00:06:40 – Face-to-face interactions dramatically declining 00:07:01 – The UK, Japan, and Australia loneliness crisis initiatives 00:07:32 – The paradox: hyperconnected but deeply isolated 00:08:04 – Loneliness as a biological alarm signal 00:08:31 – What loneliness actually looks like in modern life 00:08:42 – The lonely CEO, the unseen mother, the isolated social media addict 00:09:31 – "Perceived social isolation" and why the brain can't tell the difference 00:10:21 – Meta-analysis of 3.4 million people 00:10:55 – Loneliness vs obesity and smoking risk comparisons 00:11:18 – The biology of loneliness begins 00:11:50 – NF-kB: inflammatory gene activation explained 00:12:33 – How loneliness changes gene expression 00:13:02 – Chronic inflammation and disease pathways 00:13:21 – Cortisol, sleep disruption, and immune dysfunction 00:14:00 – How loneliness affects brain repair and amyloid plaque clearing 00:14:21 – Sponsor: Fatty15 and cellular health 00:18:02 – The Alzheimer's and dementia connection 00:18:25 – Loneliness as a major modifiable dementia risk factor 00:18:57 – Cortisol, neuroinflammation, and brain degeneration 00:19:16 – The hippocampus physically shrinking in lonely people 00:19:27 – Social media as a "fatal convenience" 00:19:57 – The oxytocin economy: connection as medicine 00:20:15 – Oxytocin as one of the body's strongest anti-inflammatory molecules 00:20:30 – HeartMath research: emotional synchronization between people 00:20:48 – "You regulate each other's biology" 00:21:07 – The real barrier: vulnerability 00:21:32 – Darin's recent experiences with radical vulnerability 00:21:54 – Conversations with family, ex-partners, and loved ones 00:22:35 – Brené Brown's research on connection and worthiness 00:23:14 – The "depth audit" exercise 00:23:42 – Reaching out, expressing appreciation, and owning your emotions 00:24:01 – Sacred hours: spending time without phones 00:24:13 – Questions that create real intimacy 00:24:30 – Darin's emotional conversation with his brother 00:25:03 – Protecting yourself from social media disconnection 00:25:20 – Becoming a source of joy and connection in everyday life 00:25:25 – Darin reflects on seven years of subtle loneliness 00:25:48 – The shift from surface conversations to meaningful connection 00:26:01 – "If you want love, give love" 00:26:19 – Final message: generate the connection you want to receive 00:26:22 – Closing thoughts and outro Thank You to Our Sponsors Truniagen: Go to www.truniagen.com and use code DARIN20 at checkout for 20% off Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness Key Takeaway "Loneliness isn't weakness. It isn't failure. It's a biological signal telling you that something essential is missing. And in a world addicted to surface-level connection, the real medicine may simply be this: vulnerability, presence, eye contact, honesty, and the courage to let yourself truly be seen." Bibliography/Sources The Loneliness Epidemic & Public Health Data Bureau of Labor Statistics. (2023). American time use survey. U.S. Department of Labor. https://www.bls.gov/tus/ Cigna. (2023). Cigna U.S. loneliness index. Evernorth Health Services. https://newsroom.cigna.com/loneliness-epidemic-continues-to-rise-cigna-study Murthy, V. H. (2023). Our epidemic of loneliness and isolation: The U.S. Surgeon General's advisory on the healing effects of social connection and community. U.S. Department of Health and Human Services. https://www.hhs.gov/sites/default/files/surgeon-general-social-connection-advisory.pdf Survey Center on American Life. (2021). The state of American friendship: Change, challenges, and loss. American Enterprise Institute. https://www.americansurveycenter.org/research/the-state-of-american-friendship-change-challenges-and-loss/ Mortality & Systemic Health Risk Cohen, S., Doyle, W. J., Skoner, D. P., Rabin, B. S., & Gwaltney, J. M. (1997). Social ties and susceptibility to the common cold. JAMA, 277(24), 1940–1944. https://pubmed.ncbi.nlm.nih.gov/9200634/ Hawkley, L. C., & Cacioppo, J. T. (2010). Loneliness matters: A theoretical and empirical review of consequences and mechanisms. Annals of Behavioral Medicine, 40(2), 218–227. https://pubmed.ncbi.nlm.nih.gov/20396846/ Holt-Lunstad, J., Smith, T. B., Baker, M., Harris, T., & Stephenson, D. (2015). Loneliness and social isolation as risk factors for mortality: A meta-analytic review. Perspectives on Psychological Science, 10(2), 227–237. https://doi.org/10.1177/1745691614568352 Valtorta, N. K., Kanaan, M., Gilbody, S., Ronzi, S., & Hanratty, B. (2016). Loneliness and social isolation as risk factors for coronary heart disease and stroke. Heart, 102(13), 1009–1016. https://heart.bmj.com/content/102/13/1009 Genetics, Inflammation & The Immune System Cole, S. W. (2013). Social regulation of human gene expression: Mechanisms and implications for public health. American Journal of Public Health, 103(S1), S84–S92. https://pmc.ncbi.nlm.nih.gov/articles/PMC3786756/ Cole, S. W., Hawkley, L. C., Arevalo, J. M. G., Sung, C. Y., Rose, R. M., & Cacioppo, J. T. (2007). Social regulation of gene expression in human leukocytes. Genome Biology, 8(9), Article R189. https://pmc.ncbi.nlm.nih.gov/articles/PMC2375027/ Sleep & Cognitive Decline Cacioppo, J. T., Hawkley, L. C., Berntson, G. G., Ernst, J. M., Gibbs, A. C., Stickgold, R., & Hobson, J. A. (2002). Do lonely days invade the nights? Potential social modulation of sleep efficiency. Psychological Science, 13(4), 384–387. https://pubmed.ncbi.nlm.nih.gov/12137144/ Holwerda, T. J., Deeg, D. J. H., Beekman, A. T. F., et al. (2014). Feelings of loneliness, but not social isolation, predict dementia onset. Journal of Neurology, Neurosurgery & Psychiatry, 85(2), 135–142. https://jnnp.bmj.com/content/85/2/135 Oxytocin & The Biology of Connection Szeto, A., Sun-Suslow, N., Mendez, A. J., Hernandez, R. I., Wagner, K. V., & McCabe, P. M. (2017). Regulation of the macrophage oxytocin receptor in response to inflammation. American Journal of Physiology—Endocrinology and Metabolism, 312(2), E183–E189. https://journals.physiology.org/doi/full/10.1152/ajpendo.00424.2016 Uvnas-Moberg, K. (2003). The oxytocin factor: Tapping the hormone of calm, love, and healing. Da Capo Press. https://books.google.com/books?id=b-aKjQoB_nQC Psychology, Vulnerability & Relationship Science Aron, A., Melinat, E., Aron, E. N., Vallone, R. D., & Bator, R. J. (1997). The experimental generation of interpersonal closeness. Personality and Social Psychology Bulletin, 23(4), 363–377. https://doi.org/10.1177/0146167297234003 Brown, B. (2010). The gifts of imperfection: Let go of who you think you're supposed to be and embrace who you are. Hazelden Publishing. https://brenebrown.com/book/the-gifts-of-imperfection/ Cacioppo, J. T., & Patrick, W. (2008). Loneliness: Human nature and the need for social connection. W. W. Norton & Company. https://wwnorton.com/books/9780393335286 Dunbar, R. I. M. (2012). Bridging evolutionary approaches to the social brain and social bonding. In F. B. M. de Waal & P. F. Ferrari (Eds.), The primate mind. Harvard University Press. https://www.hup.harvard.edu/books/9780674063104 Dunbar, R. I. M. (2021). Friends: Understanding the power of our most important relationships. Little, Brown and Company. https://www.hachettebookgroup.com/titles/robin-dunbar/friends/9781408711736/ Waldinger, R., & Schulz, M. (2023). The good life: Lessons from the world's longest scientific study on happiness. Simon & Schuster. https://www.simonandschuster.com/books/The-Good-Life/Robert-Waldinger/9781982166694

In this episode, Dr. Gladden and nutrition expert Sarah Kennedy discuss Calocurb, a natural extract that uses evolutionary biology to suppress appetite. The discovery focuses on bitter taste receptors (T2Rs) located throughout the gastrointestinal tract, which historically served as a protective mechanism to slow the consumption of potentially toxic substances. By using a specific New Zealand hop extract, Calocurb triggers these receptors to signal the brain that the body is full. This process stimulates the natural release of satiety hormones—GLP-1, CCK, and PYY—effectively quieting "hunger noise" and reducing caloric intake without the need for synthetic pharmaceuticals.   For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now   Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!    Takeaways ·       Sarah Kennedy transitioned from veterinary medicine to nutrition. ·       Calocurb is based on the hypothesis of appetite suppression through bitter taste receptors. ·       Bitter taste receptors are present throughout the gastrointestinal tract. ·       The primary hormones involved in appetite suppression are CCK, GLP-1, and PYY. ·       Clinical studies showed an 18% reduction in calorie intake with Calocurb. ·       Calocurb has a duration of action of four to six hours. ·       5% of users may experience a laxative effect as a side effect. ·       The product can be used intermittently for weight management. ·       Future research will explore the effects of Calocurb on adolescents and gut health. ·       Calocurb is a natural alternative to synthetic appetite suppressants.   Chapters 00:00 Introduction to Calocurb and Sarah's Background 02:52 The Science Behind Appetite Suppression 05:56 Mechanisms of Action: Hormones and Receptors 08:55 Clinical Studies and Results of Calocurb 11:50 Long-term Effects and Usage Recommendations 14:57 Side Effects and Adaptation 17:57 Future Research and Development Plans 21:01 Conclusion and Where to Find Calocurb To learn more about Sarah Kennedy: Facebook: https://www.facebook.com/calocurbGLOBAL/ Instagram: https://www.instagram.com/calocurb Website: www.calocurb.com   Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw    

If you enjoy this episode, we're sure you will enjoy more content like this on The Occult Rejects.  In fact, we have curated playlists on occult topics like grimoires, esoteric concepts and phenomena, occult history, analyzing true crime and cults with an occult lens, Para politics, and occultism in music. Whether you enjoy consuming your content visually or via audio, we've got you covered - and it will always be provided free of charge.  So, if you enjoy what we do and want to support our work of providing accessible, free content on various platforms, please consider making a donation to the links provided below.  Thank you and enjoy the episode!Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Cash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejectsBibliography / Show NotesAmaya, I. A., Behrens, F., et al. “Effect of Frequency and Rhythmicity on Flicker Light-Induced Visual Hallucinations.” PLOS ONE, 2023.Key use: frequency, rhythmicity, 10 Hz flicker, Klüver forms.Shenyan, O., Lisi, M., Greenwood, J. A., Skipper, J. I., & Dekker, T. M. “Visual Hallucinations Induced by Ganzflicker and Ganzfeld Differ in Frequency, Complexity, and Content.” Scientific Reports, 2024.Key use: Ganzfeld vs. Ganzflicker.Bressloff, P. C., Cowan, J. D., Golubitsky, M., Thomas, P. J., & Wiener, M. C. “Geometric Visual Hallucinations, Euclidean Symmetry and the Functional Architecture of Striate Cortex.” Philosophical Transactions of the Royal Society B, 2001.Key use: form constants, tunnels, spirals, lattices, honeycombs, visual cortex modeling.Bressloff, P. C. “What Geometric Visual Hallucinations Tell Us About the Visual Cortex.” Neural Computation, 2002.Key use: Klüver form constants and visual cortex explanation.Mauro, F., et al. “A Bidirectional Link Between Brain Oscillations and Geometric Patterns.” Journal of Neuroscience, 2015.Key use: brain oscillations and geometric visual patterns.Hewitt, T., et al. “Stroboscopically Induced Visual Hallucinations.” Neuroscience of Consciousness, 2025.Key use: history and science of stroboscopic hallucinations.Netherlands Institute for Neuroscience. “Hallucinations from Flickering Lights: What Happens in Our Brain?” 2024.Key use: standing waves / visual cortex explanation.Purkinje, J. E. Early 19th-century writings on subjective visual phenomena and flicker effects.Key use: historical scientific observation of flicker-induced visual effects.Klüver, H. Mescal and Mechanisms of Hallucinations. University of Chicago Press, 1966.Key use: form constants: tunnels, spirals, lattices, cobwebs.Epilepsy Foundation / clinical photosensitivity guidance.Key use: photosensitive epilepsy safety warning; flashing lights and visual patterns can trigger seizures in susceptible people.“Visually-Provoked Seizures: Consensus of the Epilepsy Foundation of America Working Group.” Epilepsia.Key use: safety, photosensitive seizure risk.Ofcom / broadcast photosensitive epilepsy standards and strobe-light safety cases.Key use: real-world risk from rapid flashing light in media environments.Extra useful context sourcesGysin, B., and Sommerville, I. Dreamachine-related writings and documentation.Key use: 20th-century flicker device, art, counterculture, visionary technology.Huxley, A. The Doors of Perception.Key use: altered perception context, though not specifically flicker science.Lewis-Williams, D. The Mind in the Cave.Key use: cave art, altered states, entoptic imagery, visionary interpretation.Eliade, M. Shamanism: Archaic Techniques of Ecstasy.Key use: older ritual technologies of altered states; use carefully as historical theory.Tart, C. T., ed. Altered States of Consciousness.Key use: broader academic framing for non-ordinary states.Vaitl, D., et al. “Psychobiology of Altered States of Consciousness.” Psychological Bulletin, 2005.Key use: general altered-state science framework.Also want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. Now let me introduce the rest of the panel and guests.

13. Nuclear Non-Proliferation and the Iranian Dispute Guest: Henry Sokolski Henry Sokolski discusses the NPTreview conference, debating whether an "inalienable right" to enrich uranium exists and the lack of enforcement mechanisms to prevent countries from manufacturing nuclear weapons. 131900 BROADWAY EVENING POSTCARD

Across TikTok, Reddit, and podcast circuits, young men are being sold a blueprint for increasing their testosterone. Known as ‘T-maxxing', this trend is a mix of diet rules, supplement stacks, gym routines, and lifestyle hacks all centered around boosting testosterone as the ultimate marker of health. But behind the steak, organ meats, and anti-soy rhetoric is a more complicated story—one that blends kernels of physiology with a heavy dose of misinformation, cherry-picked science, and cultural anxiety. So join us, two registered dietitians, as we unpack the science of testosterone, break down the foods and supplements at the center of T-maxxing, and explore the deeper cultural forces driving this trend—from body image to belonging to the pressure to “optimize” masculinity—even when that pressure is built on shaky science and unrealistic ideals.Want to support the show and get bonus episodes? Join our Patreon! https://www.patreon.com/nutritionformortalsLeave us a voicemail that may be featured on a future episode! Call us at (562)-N4M-POD1 (562-646-7631). We've got MERCH! Check it out HEREDon't want to miss any episodes in the future? Make sure to subscribe wherever you listen to podcasts!Things we talked about and additional reading: Testosterone in hunter-gatherer men #1Testosterone in hunter-gatherer men #2Secular trends in testosterone over timeCholesterol intake not associated with total testosterone levels in menAssociations between vitamin D status and testosterone levels in menAssociations between omega-3 FA and testosterone levels in men Fish Intake and Serum Testosterone Levels in Older MalesHuberman Partners with Momentous Supplements Andrew Huberman's Mechanisms of Control | NY MagTongkat Ali meta-analysis Testosterone and human behavior Testosterone causes both prosocial and antisocial status-enhancing behaviors in human malesTestosterone and cortisol “dual hormone hypothesis”Experiment with manipulated “win” or “loss” on androgens and psychology in men Gynecomastia and soy case report #1 Gynecomastia and soy case report #2Meta-Analysis: intake of soy on reproductive hormones in men Are Soy isoflavones truly a public health concern?Gynecomastia from meat in Italian school Gynecomastia from meat in Puerto Rican Children For feedback or to suggest a show topic email us at nutritionformortals@gmail.comFeel free to contact our real, live nutrition counseling practice**This podcast is for information purposes only, is not a substitute for individual medical or mental health advice, and does not constitute a patient-provider relationship**

Feeling constantly drained, foggy, or just not quite right, even with a healthy diet? The invisible culprit might be chronic stress, silently stealing my body's vital micronutrients. In this episode, we uncover the profound and often-overlooked connection between stress, cortisol, and the essential vitamins and minerals your body desperately needs. I dive deep into how chronic stress directly depletes crucial nutrients like magnesium, B vitamins, vitamins C, E, D, zinc, and calcium, revealing the intricate biological mechanisms at play. Topics discussed: - The impact of stress on overall health and micronutrient status- Direct micronutrient depletion by chronic stress- Mechanisms of direct depletion - Indirect micronutrient depletion by stress- The link between stress, gut health, and absorption of nutrients - The role of poor food choices- Identifying signs of micronutrient depletion- Strategic supplementation - Utilizing tools---------- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.metabolismschool.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- [Free] Metabolism School 101: The Video Series⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.metabolismschool.com/metabolism-101⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------Subscribe to My Youtube Channel: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grab a Copy of My New Book - Metabolism Made Simple⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- Stay Connected: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube: SamMillerScience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook: The Nutrition Coaching Collaborative Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠operations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@sammillerscience.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."

What if one of the biggest health threats on Earth… is something you can't see, taste, or even fully measure yet? In this urgent solo episode, Darin breaks down the rapidly escalating crisis of microplastics and nanoplastics infiltrating our bodies, water systems, and environment. What was once dismissed is now being acknowledged at the highest levels, with government agencies scrambling to understand and contain the damage. From plastics crossing the blood-brain barrier to disrupting hormones and carrying toxic chemicals deep into human tissue, this episode exposes the hidden cost of modern convenience, and more importantly, gives you practical, immediate actions you can take to protect yourself and your family. What You'll Learn Why microplastics are now considered a global health emergency How plastics accumulate in your body and environment The shocking truth about nanoplastics crossing the blood-brain barrier How plastics act as endocrine disruptors affecting hormones The connection between plastics and inflammation, fertility, and disease Why tap water and bottled water are both major exposure sources The role of PFAS ("forever chemicals") in long-term health damage How to filter and detox microplastics from your body Emerging science on breaking down plastics using bacteria and plants Simple, actionable steps to dramatically reduce your exposure Chapters 00:00:00 – Welcome to SuperLife 00:02:12 – Opening: committing to a clean, conscious life 00:02:27 – Fatal conveniences and why awareness matters 00:02:46 – Government officially flags microplastics as a crisis 00:03:04 – $100M+ initiatives to understand plastic contamination 00:03:38 – Microplastics in drinking water and daily exposure 00:04:20 – Plastics found in babies and human brains 00:04:45 – Why we still don't understand the full damage 00:05:08 – Nanoplastics crossing the blood-brain barrier 00:05:33 – Plastics as endocrine disruptors 00:06:02 – Hormonal imbalance, inflammation, and toxicity 00:06:30 – PFAS and the "forever chemical" crisis 00:06:59 – The #1 rule: stop using single-use plastic bottles 00:07:27 – Hidden dangers of "BPA-free" plastics 00:07:58 – Why you can no longer trust tap water 00:08:30 – The importance of high-quality water filtration 00:09:11 – Reverse osmosis systems and best practices 00:10:17 – Detox strategies: sweating and sauna use 00:10:59 – Fiber and plant-based diets binding toxins 00:11:24 – Medicinal mushrooms and beta glucans 00:11:52 – Microbes that break down plastic polymers 00:12:32 – Plant-based flocculants (okra, fenugreek) removing plastics 00:13:20 – Bio-sponges and advanced filtration innovations 00:13:46 – Magnetic separation technology 00:14:27 – Microplastics from clothing and laundry systems 00:15:16 – AI-assisted filtration and regulatory changes 00:15:55 – Light-activated breakdown of plastics 00:16:03 – Boiling water to remove up to 90% of microplastics 00:16:33 – Practical emergency water filtration methods 00:16:59 – Creating a low-toxicity lifestyle at home 00:17:20 – Final message: take control and protect your health 00:17:32 – Outro     Thank You to Our Sponsors Tru Niagen – Boost NAD+ levels for cellular health and longevity. Get 20% off with code DARIN20 at truniagen.com. Shakeology – Shakeology-All in One Nutrition: Get 15% off with code SUPERLIFE at Shakeology.com.     Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only $7.49/month at https://patreon.com/darinolien     Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness     Key Takeaway: "We are living in a world where convenience has quietly introduced toxins into nearly every aspect of our lives, but you are not powerless. The moment you become aware, you can take action. And the small choices you make every day: what you drink from, how you filter your water, what you put into your body, can dramatically shift your long-term health and your family's future."     Bibliography/Sources: The News Hook — EPA CCL6 & STOMP Initiative Chemical & Engineering News. (2026, April 3). US government targets microplastics for research and potential drinking-water regulation. American Chemical Society. https://cen.acs.org Environmental Protection Agency. (2026, April 2). EPA takes bold action to ensure drinking water is safe from microplastics, pharmaceuticals, and potential hidden contaminants [Press release]. https://www.epa.gov/newsreleases Environmental Protection Agency & Department of Health and Human Services. (2026, April 2). EPA, HHS announce historic actions to protect Americans from microplastics and safeguard drinking water [Press release]. https://www.epa.gov/newsreleases Inside Climate News. (2026, April 3). 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