Podcasts about mechanisms

Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Substackhttps://substack.com/@theoccultrejects?r=7auau0&utm_campaign=profile&utm_medium=profile-pageCash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejectsBibliographyCurses, Blessings, and Ritual HarmCannon, Walter B. “‘Voodoo' Death.” American Anthropologist 44, no. 2 (1942): 169–181.Faraone, Christopher A. Ancient Greek Love Magic. Cambridge, MA: Harvard University Press, 1999.Gager, John G., ed. Curse Tablets and Binding Spells from the Ancient World. New York: Oxford University Press, 1992.Graf, Fritz. Magic in the Ancient World. Translated by Franklin Philip. Cambridge, MA: Harvard University Press, 1997.Ogden, Daniel. Magic, Witchcraft, and Ghosts in the Greek and Roman Worlds: A Sourcebook. 2nd ed. New York: Oxford University Press, 2009.Stratton, Kimberly B., and Dayna S. Kalleres, eds. Daughters of Hecate: Women and Magic in the Ancient World. New York: Oxford University Press, 2014.Tambiah, Stanley Jeyaraja. “The Magical Power of Words.” Man 3, no. 2 (1968): 175–208.Placebo, Nocebo, and Medical CommunicationBarsky, Arthur J., Ralph Saintfort, Malcolm P. Rogers, and Jonathan F. Borus. “Nonspecific Medication Side Effects and the Nocebo Phenomenon.” JAMA 287, no. 5 (2002): 622–627.Benedetti, Fabrizio. Placebo Effects: Understanding the Mechanisms in Health and Disease. Oxford: Oxford University Press, 2009.Benedetti, Fabrizio, Marina Lanotte, Lorella Lopiano, and Luana Colloca. “When Words Are Painful: Unraveling the Mechanisms of the Nocebo Effect.” Neuroscience 147, no. 2 (2007): 260–271.Colloca, Luana, and Fabrizio Benedetti. “Nocebo Hyperalgesia: How Anxiety Is Turned into Pain.” Current Opinion in Anaesthesiology 20, no. 5 (2007): 435–439.Colloca, Luana, and Damien Finniss. “Nocebo Effects, Patient–Clinician Communication, and Therapeutic Outcomes.” JAMA 307, no. 6 (2012): 567–568.Colloca, Luana, and Franklin G. Miller. “The Nocebo Effect and Its Relevance for Clinical Practice.” Psychosomatic Medicine 73, no. 7 (2011): 598–603.Enck, Paul, Fabrizio Benedetti, and Manfred Schedlowski. “New Insights into the Placebo and Nocebo Responses.” Neuron 59, no. 2 (2008): 195–206.Häuser, Winfried, Ernil Hansen, and Paul Enck. “Nocebo Phenomena in Medicine: Their Relevance in Everyday Clinical Practice.” Deutsches Ärzteblatt International 109, no. 26 (2012): 459–465.Inner Speech and DevelopmentFernyhough, Charles. The Voices Within: The History and Science of How We Talk to Ourselves. New York: Basic Books, 2016.Vygotsky, Lev S. Thought and Language. Revised and expanded ed. Edited and translated by Alex Kozulin. Cambridge, MA: MIT Press, 1986.Winsler, Adam, Charles Fernyhough, and Ignacio Montero, eds. Private Speech, Executive Functioning, and the Development of Verbal Self-Regulation. Cambridge: Cambridge University Press, 2009.Rumination and Repetitive Negative ThinkingBrosschot, Jos F., Bart Verkuil, and Julian F. Thayer. “Conscious and Unconscious Perseverative Cognition: Is a Large Part of Prolonged Physiological Activity Due to Unconscious Stress?” Journal of Psychosomatic Research 69, no. 4 (2010): 407–416.Ehring, Thomas, and Edward R. Watkins. “Repetitive Negative Thinking as a Transdiagnostic Process.” International Journal of Cognitive Therapy 1, no. 3 (2008): 192–205.Nolen-Hoeksema, Susan. “Responses to Depression and Their Effects on the Duration of Depressive Episodes.” Journal of Abnormal Psychology 100, no. 4 (1991): 569–582.Nolen-Hoeksema, Susan, Blair E. Wisco, and Sonja Lyubomirsky. “Rethinking Rumination.” Perspectives on Psychological Science 3, no. 5 (2008): 400–424.Smith, Jeannette M., and Lauren B. Alloy. “A Roadmap to Rumination: A Review of the Definition, Assessment, and Conceptualization of This Multifaceted Construct.” Clinical Psychology Review 29, no. 2 (2009): 116–128.Treynor, Wendy, Richard Gonzalez, and Susan Nolen-Hoeksema. “Rumination Reconsidered: A Psychometric Analysis.” Cognitive Therapy and Research 27, no. 3 (2003): 247–259.Watkins, Edward R. “Constructive and Unconstructive Repetitive Thought.” Psychological Bulletin 134, no. 2 (2008): 163–206.Watkins, Edward R. Rumination-Focused Cognitive-Behavioral Therapy for Depression. New York: Guilford Press, 2016.Self-Talk and PerformanceHardy, James. “Speaking Clearly: A Critical Review of the Self-Talk Literature.” Psychology of Sport and Exercise 7, no. 1 (2006): 81–97.Hatzigeorgiadis, Antonis, Nikos Zourbanos, Evangelos Galanis, and Yiannis Theodorakis. “Self-Talk and Sports Performance: A Meta-Analysis.” Perspectives on Psychological Science 6, no. 4 (2011): 348–356.Theodorakis, Yiannis, Antonis Hatzigeorgiadis, and Nikos Zourbanos. “Cognition: Self-Talk and Performance.” In The Oxford Handbook of Sport and Performance Psychology, edited by Shane M. Murphy. New York: Oxford University Press, 2012.Affect Labeling, Emotion, and LanguageBarrett, Lisa Feldman. “Solving the Emotion Paradox: Categorization and the Experience of Emotion.” Personality and Social Psychology Review 10, no. 1 (2006): 20–46.Lieberman, Matthew D., Naomi I. Eisenberger, Molly J. Crockett, Sabrina M. Tom, Jennifer H. Pfeifer, and Baldwin M. Way. “Putting Feelings into Words: Affect Labeling Disrupts Amygdala Activity in Response to Affective Stimuli.” Psychological Science 18, no. 5 (2007): 421–428.Lindquist, Kristen A., Lisa Feldman Barrett, Eliza Bliss-Moreau, and James A. Russell. “Language and the Perception of Emotion.” Emotion 6, no. 1 (2006): 125–138.Torre, Jared B., and Matthew D. Lieberman. “Putting Feelings into Words: Affect Labeling as Implicit Emotion Regulation.” Emotion Review 10, no. 2 (2018): 116–124.Self-Distancing and Reflective ProcessingAyduk, Özlem, and Ethan Kross. “From a Distance: Implications of Spontaneous Self-Distancing for Adaptive Self-Reflection.” Journal of Personality and Social Psychology 98, no. 5 (2010): 809–829.Kross, Ethan, and Özlem Ayduk. “Making Meaning out of Negative Experiences by Self-Distancing.” Current Directions in Psychological Science 20, no. 3 (2011): 187–191.Kross, Ethan, Özlem Ayduk, and Walter Mischel. “When Asking ‘Why' Does Not Hurt: Distinguishing Rumination from Reflective Processing of Negative Emotions.” Psychological Science 16, no. 9 (2005): 709–715.Kross, Ethan, Emma Bruehlman-Senecal, Jiyoung Park, Aleah Burson, Adrienne Dougherty, Holly Shablack, Ryan Bremner, Jason Moser, and Özlem Ayduk. “Self-Talk as a Regulatory Mechanism: How You Do It Matters.” Journal of Personality and Social Psychology 106, no. 2 (2014): 304–324.Moser, Jason S., Adrienne Dougherty, Whitney I. Mattson, Benjamin Katz, Tim P. Moran, Darwin Guevarra, Hannah Shablack, et al. “Third-Person Self-Talk Facilitates Emotion Regulation Without Engaging Cognitive Control: Converging Evidence from ERP and fMRI.” Scientific Reports 7 (2017): 4519.Affirmation and Counter-IncantationCascio, Christopher N., Matthew B. O'Donnell, Francis J. Tinney Jr., Matthew D. Lieberman, Shelley E. Taylor, Victor J. Strecher, and Emily B. Falk. “Self-Affirmation Activates Brain Systems Associated with Self-Related Processing and Reward and Is Reinforced by Future Orientation.” Social Cognitive and Affective Neuroscience 11, no. 4 (2016): 621–629.Cohen, Geoffrey L., and David K. Sherman. “The Psychology of Change: Self-Affirmation and Social Psychological Intervention.” Annual Review of Psychology 65 (2014): 333–371.Wood, Joanne V., W. Q. Elaine Perunovic, and John W. Lee. “Positive Self-Statements: Power for Some, Peril for Others.” Psychological Science 20, no. 7 (2009): 860–866.Implementation Intentions and ActionGollwitzer, Peter M. “Implementation Intentions: Strong Effects of Simple Plans.” American Psychologist 54, no. 7 (1999): 493–503.Gollwitzer, Peter M., and Veronika Brandstätter. “Implementation Intentions and Effective Goal Pursuit.” Journal of Personality and Social Psychology 73, no. 1 (1997): 186–199.Gollwitzer, Peter M., and Paschal Sheeran. “Implementation Intentions and Goal Achievement: A Meta-Analysis of Effects and Processes.” Advances in Experimental Social Psychology 38 (2006): 69–119.Schweiger Gallo, Inge, Andreas Keil, Kathleen C. McCulloch, Brigitte Rockstroh, and Peter M. Gollwitzer. “Strategic Automation of Emotion Regulation.” Journal of Personality and Social Psychology 96, no. 1 (2009): 11–31.Ritual, Identity, and Psychological FormationBell, Catherine. Ritual Theory, Ritual Practice. New York: Oxford University Press, 1992.Hobson, Nicholas M., Juliana Schroeder, Jane L. Risen, Dimitris Xygalatas, and Michael Inzlicht. “The Psychology of Rituals: An Integrative Review and Process-Based Framework.” Personality and Social Psychology Review 22, no. 3 (2018): 260–284.Rappaport, Roy A. Ritual and Religion in the Making of Humanity. Cambridge: Cambridge University Press, 1999.Xygalatas, Dimitris. Ritual: How Seemingly Senseless Acts Make Life Worth Living. New York: Little, Brown Spark, 2022.Also want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. 

Register free at https://geneticsurvival.com/  to watch the full Unbreakable stream Stay informed on current events, visit www.NaturalNews.com  - Professor Zhang Interview Preview (0:10) - New Genetic Survival Course Announcement (3:15) - AI-Generated Visual Demonstrations (5:13) - The Unbreakable Music Video (7:17) - Mechanisms of Genetic Repair (28:11) - American Food and Healthcare Systems (121:33) Watch more independent videos at http://www.brighteon.com/channel/hrreport  ▶️ Support our mission by shopping at the Health Ranger Store - https://www.healthrangerstore.com ▶️ Check out exclusive deals and special offers at https://rangerdeals.com ▶️ Sign up for our newsletter to stay informed: https://www.naturalnews.com/Readerregistration.html Watch more exclusive videos here:

Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition.   Dr. Pak's Links: Website: drpak.com Instagram: @dr__pak YouTube: @Dr__Pak Book: Train Smarter, Not Longer Timestamps 00:00 Knicks, the World Cup, and European sports culture 07:46 Is one set enough to build muscle? 11:28 What the research says about volume and strength 14:33 Low-volume training for muscle and health 18:58 Mechanisms versus real-world training outcomes 21:17 Building muscle versus maintaining it 28:47 Progressive overload and ramping up volume 34:54 Strength gains versus muscle growth 40:01 Why all-out intensity is romanticized 47:13 Practical volume and intensity takeaways  

In this Wellness Tech installment, Jonathan Mendoza, DC, APRN, NP-C — Nurse Doza — explains why red light panels have become a daily fixture in his clinic and his home. He covers how red and near-infrared wavelengths reach the mitochondria to support healthy ATP production, why panels deliver solar-style input without UV exposure, how he personally uses violet light to wind down at night, and what the emerging 40Hz gamma-frequency research does and does not yet show in humans. FEATURED PARTNER LightpathLED builds veteran-owned red and near-infrared light therapy panels. Nurse Doza uses one daily and highlights this brand specifically because it offers more than a single red setting — it includes violet-spectrum output and adjustable frequency, including a 40Hz option he notes he hasn't found on other consumer panels. Shop: https://lightpathled.com Code: NURSEDOZA (discount applied at checkout) Current promo:Select Diesel Gen3 panels ship with a free stand — verify at checkout, promos change Join the School of Doza The School of Doza is a paid health-education community with live group consults every **Wednesday at 1 PM Central**, plus courses, protocols, and direct access to Nurse Doza. Start your free trial: https://www.schoolofdoza.com --- 5 Key Takeaways 1. Red and near-infrared light interact with your mitochondria, not just your skin.These wavelengths are absorbed by cytochrome c oxidase in the electron transport chain, which supports healthy ATP production — the mechanism researchers call photobiomodulation. 2. A panel delivers solar-style light input without the UV load.Most people spend the majority of daylight hours indoors under light their cells don't recognize. Red light panels are one way to add that input without the burn risk that comes with UV exposure. 3. Panels are low-friction to use. No undressing required — Nurse Doza sits in front of his and lets it hit his forehead. He uses sessions in the two-to-five-minute range as his own personal routine, not a prescribed protocol. 4. Violet light sits at the opposite end of the visible spectrum from red. Nurse Doza reports using violet output in the evening as part of his wind-down. This is his subjective experience — violet-specific calming effects are not yet well established in the peer-reviewed literature. 5. The 40Hz frequency setting is an area of active research, not settled science. Gamma-frequency entrainment at 40Hz has been studied for its effects on brain activity, but the most-cited amyloid findings are from animal models and have published author corrections. Interesting, worth following — not a treatment. Citations: 1. de Freitas LF, Hamblin MR. **Proposed Mechanisms of Photobiomodulation or Low-Level Light Therapy.** *IEEE Journal of Selected Topics in Quantum Electronics.* 2016. PMID: 28070154 — https://pubmed.ncbi.nlm.nih.gov/28070154/ 2. Hamblin MR. **Mechanisms and Mitochondrial Redox Signaling in Photobiomodulation.** *Photochemistry and Photobiology.* 2018. PMID: 29164625 — https://pubmed.ncbi.nlm.nih.gov/29164625/ 3. Maghfour J, Ozog DM, Mineroff J, Jagdeo J, Kohli I, Lim HW. **Photobiomodulation CME Part I: Overview and Mechanism of Action.** *Journal of the American Academy of Dermatology.* 2024. PMID: 38309304 — https://pubmed.ncbi.nlm.nih.gov/38309304/ 4. Nairuz T, Cho S, Lee JH. **Photobiomodulation Therapy on Brain: Pioneering an Innovative Approach to Revolutionize Cognitive Dynamics.** *Cells.* 2024. PMID: 38891098 — https://pubmed.ncbi.nlm.nih.gov/38891098/ 5. Iaccarino HF, Singer AC, Martorell AJ, et al. **Gamma frequency entrainment attenuates amyloid load and modifies microglia.** *Nature.* 2016;540:230–235. PMID: 27929004 · PMCID: PMC5656389 — https://pmc.ncbi.nlm.nih.gov/articles/PMC5656389/    *Note: animal-model study. Two author corrections have since been published (2018, 2024).* Bonus — sleep and LED light therapy: Liao YH, Tai CJ, Ming JL, Lin LH, Chien LY. **The Effectiveness of Low-Level LED Light Therapy for Sleep Problems, Psychological Symptoms, and Heart Rate Variability in Shift-Work Nurses: A Randomized Controlled Trial.** *Journal of Nursing Management.* 2025. PMID: 40557249 — https://pubmed.ncbi.nlm.nih.gov/40557249/

On June 22, 2026, the Lymphoma Hub held a virtual symposium, titled Optimizing treatment for chronic lymphocytic leukemia with BTK inhibitors. During the symposium, Lymphoma Hub Steering Committee member Susan O'Brien, University of California Irvine, US, delivered a presentation on BTK inhibitors in chronic lymphocytic leukemia: Mechanisms, clinical considerations, and unmet needs. This educational resource is independently supported by Eli Lilly and Company. All content is developed by SES in collaboration with an expert steering committee. Funders are allowed no influence. Hosted on Acast. See acast.com/privacy for more information.

An approach to dyspnea (shortness of breath), including the dyspnea pyramid to remember the differentials, as well as key investigations that help identify the cause, as well as common patterns in the history and physical examination. PDFs available here: https://rhesusmedicine.com/products/assessment-or-interpretationConsider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1Patreon: https://www.patreon.com/rhesusmedicineBuy Us A Coffee!: https://www.buymeacoffee.com/rhesusmedicineTimestamps:0:00 What is Dyspnea?0:19 The Dyspnea Pyramid2:50 Dyspnea History & Physical Exam Patterns4:43 Dyspnea InvestigationsLINK TO MNEMONICS:https://www.youtube.com/watch?v=p-XE7PiwGgE&list=PLGNSE_HvIV4t7a33bbHN1fq-j_tge0GmpLINK TO SOCIAL MEDIA: https://www.instagram.com/rhesusmedicine/Please remember this podcast and all content from Rhesus Medicine is meant for educational purposes only and should not be used as a guide to diagnose or to treat. Please consult a healthcare professional for medical advice. ReferencesBMJ Best Practice (2025) Evaluation of dyspnoea in adults. BMJ Publishing Group.BMJ Best Practice (2025) Acute dyspnoea. BMJ Publishing Group.National Institute for Health and Care Excellence (2025) Breathlessness. Clinical Knowledge Summaries (CKS).MSD Manual Professional Edition (2025) Dyspnea. MSD Manual Professional Edition.StatPearls (2024) Dyspnea. In: StatPearls. Treasure Island (FL): StatPearls Publishing.Parshall, M.B., Schwartzstein, R.M., Adams, L., Banzett, R.B., Manning, H.L., Bourbeau, J., Calverley, P.M.A., Gift, A.G., Harver, A., Lareau, S.C., Mahler, D.A. and O'Donnell, D.E. (2012) An Official American Thoracic Society Statement: Update on the Mechanisms, Assessment, and Management of Dyspnea. American Journal of Respiratory and Critical Care Medicine, 185(4), pp.435–452.

VAERS stands for the 'Vaccine Adverse Effects Reporting System.' $ BTC 63,961 Block Height 961,091 Today's guest is Dr. Jessica Rose, PhD, MSc, BSc. Jessica is a Senior Fellow specializing in Computational Biology from Canada. She holds a Bachelor's Degree in applied mathematics and a master's degree in Immunology from Memorial University of Newfoundland, and a PhD in Computational Biology from Bar Ilan University. Dr. Rose has completed two post-doctoral degrees in Molecular Biology from the Hebrew University of Jerusalem, and in Biochemistry from the Technion Institute of Technology. She is best known for her contributions to public health and safety related to the COVID-19 injectable products, and her analyses of pharmacovigilance databases like VAERS. She joined me to discuss her analysis of the VAERS database and her critiques of the COVID-19 vaccine rollout and broader public health narratives. Key Topics: Analysis of the Vaccine Adverse Effects Reporting System (VAERS) Criticisms of COVID-19 mRNA injection data and safety Mechanisms of autoimmunity and potential side effects Data censorship and manipulation in scientific literature Historical context of vaccine liability and regulatory failures Strategies for immune optimization and health freedom Follow Jessica below. X- @JesslovesMJK https://jessicar.substack.com https://orcid.org/0000-0002-9091-4425 A huge thank you to Jessica for coming on the show! Check out my book ‘Choose Life' - https://bit.ly/4gGYqRE Pleb Service Announcements: Join 20 thousand Bitcoiners on @cluborange https://signup.cluborange.org/co/princey CONFERENCES: BTC HEL - 25th - 26th September 2026. - Helsinki https://btchel.com/ Use code BITTEN for - 10% My First Bitcoin. https://myfirstbitcoin.org/ Shills and Mench's: BITBOX - SELF CUSTODY YOUR BITCOIN - www.bitbox.swiss/bitten Use Code BITTEN THE MEETUP BREAKDWON - BITCOIN EVENTS UK - https://www.themeetupbreakdown.com/ SWAN BITCOIN - www.swan.com/bitten HODL EYEWEAR - Avoid Blue light! https://hodleyewear.com/partner/3/ PLEBEIAN MARKET - BUY AND SELL STUFF FOR SATS; https://plebeian.market/ @PlebeianMarket SATSBACK - Shop online and earn back sats! https://satsback.com/register/5AxjyPRZV8PNJGlM ALL FURTHER LINKS HERE - FOR DISCOUNTS AND OFFERS - https://vida.page/princey - https://linktr.ee/princey21m

Explore emerging B-cell-targeted therapies for immunoglobulin A nephropathy (IgAN). Unpack novel mechanisms of action (MOAs) and the latest clinical data to protect kidneys now. Credit available for this activity expires: 8/5/27 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/why-target-april-iga-nephropathy-management-get-speed-2026a1000ooh?ecd=bdc_podcast_libsyn_mscpedu

Our podcast features two guests described by our podcast host, Dr Jane Barratt as positive disrupters or by themselves jokingly as radical trialists. What's clear is that something significant is on the horizon: mounting evidence linking acute respiratory infections and non-communicable diseases (NCDs). Cardiovascular diseases, diabetes, cancers, asthma and COPD all fall into the category of NCDs that can be exacerbated by respiratory infections. In turn, these conditions can exacerbate the viral infections causing flu, COVID and RSV.We know that vaccinating against a respiratory infection reduces the burden of NCD management on health care. But the WHY and HOW remain unclear. What's needed is research into pathogen-specific mechanisms, clinical meaningful endpoints for prevention and better risk-stratification. Listen to eye-opening findings from the FLUNITY-HD trial and why respiratory infections can be described as systemic stress tests.In a highly informative and engaging conversation, brimming with facts and insights, Marco Goeijenbier (ESWI Board Member, intensivist at Spaarne Gasthuis and Senior Scientist at Erasmus MC) and Tor Biering-Sørensen (cardiologist and Founding Head of the Center for Translational Cardiology in Copenhagen) discuss what we know, and where science still needs to mature in this pioneering field.

Jason Brown returns for a nuanced discussion about Zone 2 cardio, walking, conditioning, stress, recovery, and how cardio should fit into an individual's life.Jason joins me to discuss:• Whether Zone 2 cardio is actually overrated• How much of Zone 2's benefit comes from simply getting people moving• The value of reducing sedentary time and increasing daily activity• The relationship between Zone 2-style activity, NEAT, and mental health• Why getting outside and moving can provide benefits beyond fitness adaptations• Looking at cardio and all training through the lens of nervous system regulation• Accounting for the total stress already present in someone's life• Why cardio recommendations should begin with the individual's available time and capacity• The nuanced debate around whether walking counts as exercise• Why sprint training should not be treated as Zone 2 cardio• Why average heart rate during lifting or high-intensity training does not prove someone received a Zone 2 stimulus• The difference between cardiovascular strain and sustained aerobic work• Why exercise labels matter less than matching the activity to the person's needs• Jason's thoughts on the current state of online coaching• And much moreFollow Jason on Instagram:@jasonbrowntrainingCHAPTERS01:04 Setting Up the Zone 2 Controversy01:59 Who Is Zone 2 Cardio For?05:05 Social Media Hot Takes07:02 The Benefits of Sustained Aerobic Work10:41 Andrew's Questions About Zone 214:45 Mechanisms and Aerobic Adaptations21:13 Time Constraints and Effective Dosing29:07 Does Walking Count as Exercise?30:53 Walking as Therapy33:20 Regulation Matters More Than Debates34:09 Plug-and-Play Training35:40 Why Speed Training Is Not Zone 237:35 The Limits of Heart Rate as a Proxy39:39 Genetics and Individual Cardio Needs44:08 Making 30 to 60 Minutes Count47:21 Assessments and Coaching Standards50:40 The Reality of Online Coaching54:49 Aerobic Training Requires Time55:45 Final Thoughts and Where to Find JasonSUPPORT THE SHOWIf this episode helped you think differently about Zone 2 cardio, walking, recovery, or conditioning:• Subscribe and check out more episodes• Share the episode on social media and tag @andrewcoatesfitness• Send it to someone who believes cardio needs to be intense to be worthwhileFOLLOW ANDREW COATESInstagram: @andrewcoatesfitnesshttps://www.andrewcoatesfitness.comPARTNERS AND RESOURCESRP STRENGTH APPUse code COATESRP:https://www.rpstrength.com/coatesJUST BITE ME MEALSUse code ANDREWCOATESFITNESS for 10% off:https://justbitememeals.comMACROSFIRST — FREE PREMIUM TRIAL• Download MacrosFirst• Begin setting up your account• When asked, “How did you hear about us?” enter: ANDREWKNKG BAGS — 15% OFFhttps://www.knkg.com/Andrew59676VERSA GRIPPShttps://www.versagripps.com/andrewcoatesTRAINHEROIC — FREE 90-DAY TRIAL• Visit: https://www.trainheroic.com/liftfree• Reply to the email you receive or email trials@trainheroic.com• Let them know Andrew sent youL1 BIOMECHANICS AND ASSESSMENT COURSEUse code COATES:https://pro.activelifeprofessional.com/assessmentworkshopevents

Robbie Williams is one of the biggest artists of all time in the United Kingdom. Why don't people know him in the United States?What makes something popular? Let's dig into the aesthetic "aha" and the ways researchers have been looking into it in the lab.For 30% off your first year with DistroKid to share your music with the world click ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠DistroKid.com/vip/lovemusicmore⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

If you enjoy this episode, we're sure you will enjoy more content like this on The Occult Rejects.  In fact, we have curated playlists on occult topics like grimoires, esoteric concepts and phenomena, occult history, analyzing true crime and cults with an occult lens, Para politics, and occultism in music. Whether you enjoy consuming your content visually or via audio, we've got you covered - and it will always be provided free of charge.  So, if you enjoy what we do and want to support our work of providing accessible, free content on various platforms, please consider making a donation to the links provided below.  Thank you and enjoy the episode!Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Substackhttps://substack.com/@theoccultrejects?r=7auau0&utm_campaign=profile&utm_medium=profile-pageCash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejectsBibliographyCore Eye Anatomy, Retina, Optic Nerve, and Visual PathwaysBelliveau, A. P., & Somani, A. N. “Pupillary Light Reflex.” StatPearls. Treasure Island, FL: StatPearls Publishing, updated 2023.Cleveland Clinic. “Optic Nerve: What It Is, Function, Anatomy & Conditions.” Cleveland Clinic, updated 2024.Gupta, M., & Ireland, A. C. “Neuroanatomy, Visual Pathway.” StatPearls. Treasure Island, FL: StatPearls Publishing, updated 2022.Kolb, H. “Simple Anatomy of the Retina.” Webvision: The Organization of the Retina and Visual System. University of Utah / NCBI Bookshelf.Purves, D., Augustine, G. J., Fitzpatrick, D., et al., eds. Neuroscience. Sunderland, MA: Sinauer Associates.Szabadi, E. “Functional Organization of the Sympathetic Pathways Controlling the Pupil: Light-Inhibited and Light-Stimulated Pathways.” Frontiers in Neurology 9, 2018.University of Texas Health Science Center at Houston. “Ocular Motor System.” Neuroscience Online.Pupillometry, Cognitive Load, Attention, and Mental EffortBeatty, Jackson. “Task-Evoked Pupillary Responses, Processing Load, and the Structure of Processing Resources.” Psychological Bulletin 91, no. 2, 1982: 276–292.Beatty, Jackson, and Brennis Lucero-Wagoner. “The Pupillary System.” In Handbook of Psychophysiology, edited by John T. Cacioppo, Louis G. Tassinary, and Gary G. Berntson. Cambridge: Cambridge University Press, 2000.Kahneman, Daniel, and Jackson Beatty. “Pupil Diameter and Load on Memory.” Science 154, no. 3756, 1966: 1583–1585.Kahneman, Daniel. Attention and Effort. Englewood Cliffs, NJ: Prentice-Hall, 1973.Laeng, Bruno, Sylvain Sirois, and Gustaf Gredebäck. “Pupillometry: A Window to the Preconscious?” Perspectives on Psychological Science 7, no. 1, 2012: 18–27.Mathôt, Sebastiaan. “Pupillometry: Psychology, Physiology, and Function.” Journal of Cognition 1, no. 1, 2018.Piquado, Tepring, David Isaacowitz, and Arthur Wingfield. “Pupillometry as a Measure of Cognitive Effort in Younger and Older Adults.” Psychophysiology 47, no. 3, 2010: 560–569.Zekveld, Adriana A., Sophia E. Kramer, and Tammo Houtgast. “The Pupil Dilation Response to Auditory Stimuli: Current State of Knowledge.” Trends in Hearing 22, 2018.Emotion, Attraction, Arousal, and the PupilBradley, Margaret M., Laura Miccoli, Miguel A. Escrig, and Peter J. Lang. “The Pupil as a Measure of Emotional Arousal and Autonomic Activation.” Psychophysiology 45, no. 4, 2008: 602–607.de Winter, Joost C. F., et al. “Replicating Five Pupillometry Studies of Eckhard Hess.” International Journal of Psychophysiology 165, 2021: 145–161.Hess, Eckhard H. “Attitude and Pupil Size.” Scientific American 212, no. 4, 1965: 46–54.Hess, Eckhard H., and James M. Polt. “Pupil Size as Related to Interest Value of Visual Stimuli.” Science 132, no. 3423, 1960: 349–350.Lang, Peter J., Margaret M. Bradley, and Bruce N. Cuthbert. International Affective Picture System (IAPS): Affective Ratings of Pictures and Instruction Manual. Gainesville: University of Florida, 2008.Pan, J., et al. “The Effects of Emotional Arousal on Pupil Size Depend on Background Luminance and Stimulus Type.” Scientific Reports 14, 2024.Locus Coeruleus, Norepinephrine, Salience, and AttentionAston-Jones, Gary, and Jonathan D. Cohen. “An Integrative Theory of Locus Coeruleus–Norepinephrine Function: Adaptive Gain and Optimal Performance.” Annual Review of Neuroscience 28, 2005: 403–450.Joshi, Siddhartha, Yin Li, Ram M. Kalwani, and Joshua I. Gold. “Relationships Between Pupil Diameter and Neuronal Activity in the Locus Coeruleus, Colliculi, and Cingulate Cortex.” Neuron 89, no. 1, 2016: 221–234.Murphy, Peter R., Ian H. Robertson, James H. Balsters, and Redmond G. O'Connell. “Pupillometry and P3 Index the Locus Coeruleus–Noradrenergic Arousal Function in Humans.” Psychophysiology 48, no. 11, 2011: 1532–1543.Sara, Susan J. “The Locus Coeruleus and Noradrenergic Modulation of Cognition.” Nature Reviews Neuroscience 10, 2009: 211–223.Uddin, Lucina Q. “Salience Processing and Insular Cortical Function and Dysfunction.” Nature Reviews Neuroscience 16, 2015: 55–61.Memory, Emotion, Initiation, and Ritual EncodingCahill, Larry, and James L. McGaugh. “Mechanisms of Emotional Arousal and Lasting Declarative Memory.” Trends in Neurosciences 21, no. 7, 1998: 294–299.McGaugh, James L. “Memory—A Century of Consolidation.” Science 287, no. 5451, 2000: 248–251.McGaugh, James L. “The Amygdala Modulates the Consolidation of Memories of Emotionally Arousing Experiences.” Annual Review of Neuroscience 27, 2004: 1–28.Seligman, Rebecca, and Laurence J. Kirmayer. “Dissociative Experience and Cultural Neuroscience: Narrative, Metaphor and Mechanism.” Culture, Medicine, and Psychiatry 32, 2008: 31–64.Seligman, Rebecca, Ryan A. Brown, and Laurence J. Kirmayer. “Theory and Method at the Intersection of Anthropology and Cultural Neuroscience.” Social Cognitive and Affective Neuroscience 5, no. 2–3, 2010: 130–139.Whitehouse, Harvey. Arguments and Icons: Divergent Modes of Religiosity. Oxford: Oxford University Press, 2000.Whitehouse, Harvey. Modes of Religiosity: A Cognitive Theory of Religious Transmission. Walnut Creek, CA: AltaMira Press, 2004.Ritual, Synchrony, Social Bonding, and Embodied MeaningHobson, Nicholas M., Juliana Schroeder, Jane L. Risen, Dimitris Xygalatas, and Michael I. Norton. “The Psychology of Rituals: An Integrative Review and Process-Based Framework.” Personality and Social Psychology Review 22, no. 3, 2018: 260–284.Jackson, Joshua Conrad, Brock Bastian, and others. “Synchrony and Physiological Arousal Increase Cohesion and Cooperation in Large Naturalistic Groups.” Scientific Reports 8, 2018.McCauley, Robert N., and E. Thomas Lawson. Bringing Ritual to Mind: Psychological Foundations of Cultural Forms. Cambridge: Cambridge University Press, 2002.Rappaport, Roy A. Ritual and Religion in the Making of Humanity. Cambridge: Cambridge University Press, 1999.Turner, Victor. The Ritual Process: Structure and Anti-Structure. Chicago: Aldine, 1969.Xygalatas, Dimitris. Ritual: How Seemingly Senseless Acts Make Life Worth Living. New York: Little, Brown Spark, 2022.Xygalatas, Dimitris, et al. “Extreme Rituals Promote Prosociality.” Psychological Science 24, no. 8, 2013: 1602–1605.Meditation, Prayer, Trance, and AbsorptionFox, Kieran C. R., Matthew L. Dixon, Savannah Nijeboer, et al. “Functional Neuroanatomy of Meditation: A Review and Meta-Analysis of 78 Functional Neuroimaging Investigations.” Neuroscience & Biobehavioral Reviews 65, 2016: 208–228.Jerath, Ravinder, John W. Crawford, Vernon A. Barnes, and Kyler Harden. “Self-Regulation of Breathing as a Primary Treatment for Anxiety.” Applied Psychophysiology and Biofeedback 40, 2015: 107–115.Lutz, Antoine, John D. Dunne, and Richard J. Davidson. “Meditation and the Neuroscience of Consciousness.” In The Cambridge Handbook of Consciousness, edited by Philip David Zelazo, Morris Moscovitch, and Evan Thompson. Cambridge: Cambridge University Press, 2007.Tellegen, Auke, and Gilbert Atkinson. “Openness to Absorbing and Self-Altering Experiences (‘Absorption'), a Trait Related to Hypnotic Susceptibility.” Journal of Abnormal Psychology 83, no. 3, 1974: 268–277.Vago, David R., and David A. Silbersweig. “Self-Awareness, Self-Regulation, and Self-Transcendence: A Framework for Understanding the Neurobiological Mechanisms of Mindfulness.” Frontiers in Human Neuroscience 6, 2012.Darkness, Sensory Deprivation, Ganzfeld, and Visual InstabilityCaputo, Giovanni B. “Strange-Face-in-the-Mirror Illusion.” Perception 39, no. 7, 2010: 1007–1008.Caputo, Giovanni B. “Visual Perception During Mirror-Gazing at One's Own Face in Patients with Depression.” The Scientific World Journal, 2014.Caputo, Giovanni B. “Strange-Face Illusions During Eye-to-Eye Gazing in Dyads.” Imagination, Cognition and Personality 38, no. 1, 2018: 51–77.Metzger, Wolfgang. “Optische Untersuchungen am Ganzfeld.” Psychologische Forschung 13, 1930: 6–29.Shenyan, O., et al. “Visual Hallucinations Induced by Ganzflicker and Ganzfeld Differ in Frequency, Complexity, and Content.” Scientific Reports 14, 2024.Wackermann, Jiří, Peter Pütz, and Carsten Allefeld. “Ganzfeld-Induced Hallucinatory Experience, Its Phenomenology and Cerebral Electrophysiology.” Cortex 44, no. 10, 2008: 1364–1378.Zuckerman, Marvin, and Nathan Cohen. “Sources of Reports of Visual and Auditory Sensations in Perceptual-Isolation Experiments.” Psychological Bulletin 61, no. 1, 19Also want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. 

Luke de Wolf is a cybersecurity professional and the author of ‘Defending Bitcoin: Industrial-Grade Cybersecurity for the Monetary Grid'.› https://x.com/lukedewolf› https://defendingbitcoin.comPARTNERS

Several themes seem to be repeating themselves again and again throughout the Book of Devarim. For example, the nation is repeatedly encouraged to not be fearful of the formidable Canaanite Nations waiting for them on the other side of the Jordan. But the one theme that repeats itself more frequently than any other is the […]

Send us Fan MailGHK-Copper and peptides in skin care, aging, and general health.TOPICS DISCUSSED:Endogenous Decline: GHK-copper levels peak in young adulthood then fall with age, reducing natural support for skin repair and collagen maintenance.Skin Penetration: Effective topical delivery depends on molecular size under and fat solubility, often improved by procedures such as microneedling that briefly disrupt the barrier.Mechanisms of Action: The peptide upregulates fibroblasts and vascular endothelial growth factor, stimulates glycosaminoglycan production, and alters expression of genes involved in tissue regeneration and oxidative stress reduction.Lasting Remodeling: Gene expression changes produce sustained collagen rebuilding that develops over weeks to months rather than delivering only transient effects.Administration Routes: Topical use is accessible and pairs well with hyaluronic acid for hydration; injectables may reach higher local concentrations but lack extensive human trial data and FDA approval for this purpose.Safety & Protocols: The compound is generally well tolerated with mild transient injection-site reactions; typical approaches use daily microgram doses for one to two months followed by off periods.Hair & Other Uses: Clinical observations indicate potential for hair shaft strengthening comparable to minoxidil with a favorable side-effect profile, alongside exploratory work in wound healing and neurological contexts.Research Needs: Expanded human studies are required to standardize dosing, confirm long-term safety, and evaluate value in neurodegeneration, lung repair, and related areas.ABOUT THE GUEST: Rahi Sarbaziha, MD is a physician in Beverly Hills, California whose practice focuses on regenerative aesthetics, hormone therapies, peptides, and interventions that support vitality, tissue repair, and overall wellness.Support the showSupport my work:Good Chemistry: Personalized, science-based health consulting. Work with Dr. Nick Jikomes directly.Affiliate Partners: Visit this link to see my affiliate partners and get discounts codes for products & services to support health.For all the ways you can support my efforts.

What causes kidney stones to form, and why are they becoming increasingly common? In Part 1, David S. Goldfarb explores the physiological mechanisms behind kidney stone disease, the evolving roles of diet, metabolism, and hydration, and the links between kidney stones and broader metabolic conditions, including metabolic syndrome and fatty liver disease. He also reflects on how advances in research have transformed our understanding of risk factors, genetics, and disease prevention.

What if the behavior you keep trying to stop is not the real problem, but a signal pointing to something deeper?Bestselling author and speaker Pam Dwyer joins I Am Refocused Radio for a powerful conversation about The Pattern Beneath, exploring what may be happening underneath overeating, overworking, overspending, over-giving, emotional reactions, shutting down, and other repeating coping patterns.Pam shares insights from her forthcoming book, Delay the Binge, a compassionate guide centered on the power of the pause. Rather than relying on shame, extremes, or another promise to start over, she explains how slowing down in the moment can create space for curiosity, awareness, and a healthier response.This conversation explores emotional triggers, relationship patterns, exhaustion, boundaries, self-trust, and how small delays can lead to meaningful change, one urge and one decision at a time.delaythebinge.com

reference: Sri Aurobindo and the Mother, The Psychic Being — Soul: Its Nature, Mission and Evolution, Section 4 The Afterlife and Rebirth, pg. 127This episode is also available as a blog post at https://sriaurobindostudies.wordpress.com/2026/07/17/the-occult-mechanisms-behind-birth-and-death/Video presentations, interviews and podcast episodes are allavailable on the YouTube Channel https://www.youtube.com/@santoshkrinsky871More information about Sri Aurobindo can be found at www.aurobindo.net  The US editions and links to e-book editions of SriAurobindo's writings can be found at Lotus Press www.lotuspress.com#Sri Aurobindo #The Mother #yoga #integral yoga #spirituality #soul #psychic being #rebirth

Continuing his exploration of once-weekly insulins, Neil Skolnik speaks with Aaron King, MD. Together, they cover the mechanisms, practical considerations, and the myriad benefits that this new therapy can have over daily basal insulin. This special episode is sponsored with support from Novo. Please listen to the episodes by clicking on the podcast player below or by freely subscribing to Diabetes Core Update via Apple Podcasts, Amazon Music, Spotify, or your preferred podcast platform. Presented by: Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Aaron King, MD. Trained in the United States Navy in Family Medicine and certified by the American College of Diabetology, Dr. King practices outpatient diabetes management in San Antonio, Texas. Selected references: Weekly Icodec versus Daily Glargine U100 in Type 2 Diabetes without Previous Insulin. N Engl J Med 2023;389:297-308 Weekly Fixed-Dose Insulin Efsitora in Type 2 Diabetes without Previous Insulin Therapy. N Engl J Med 2025;393:325-335

Haystack Full of Needles: A memoir of research on mechanisms of memory in the decades that defined neuroscience by Louis Neal Irwin https://www.amazon.com/dp/1664140603 Lirwin.org How do we store information in the brain? Is memory a thing in a place, like a specific molecule in a particular cell? Or does learning require a process in a population, like neurons firing in a specific pattern for each experience? This combination of memoir and history tells the story of how the mechanisms of memory were gradually revealed, through biographical vignettes of the scientists who set out to solve the riddle of memory, including the author?s own efforts as he was coming of age as a scientist. It shows how individual goals intertwine with the technologies at hand to push scientific knowledge forward, often erratically, and always in the context of social forces and private ups and downs. Not only a compelling personal story with the war in Vietnam, civil rights movement, and downfall of two presidents as backdrop, this is a lucid explanation of brain function for the nonscientist and valuable contribution to the history of science in the decades that saw neuroscience join molecular biology as the marquee biomedical accomplishments of the twentieth century About the author Writer, neuroscientist, astrobiologist, educator, and political activist. Born in West Texas and raised in San Antonio, now current resident of Denver. Former Professor and Chair of Biological Sciences at the University of Texas at El Paso. Previously lived in Lubbock TX, Lawrence KS, New York City, Detroit, and Newton MA, serving four terms there on the Board of Aldermen. Recently a Court Appointed Special Advocate for abused and neglected children, and current chair of the Public Policy Committee of the Democratic Party of Denver. Co-author of “Life in the Universe” and “Cosmic Biology”, and author of “Scotophobin”

In the biotech industry, advancing cell-based therapies is not just about innovation. It's about solving real gaps where conventional treatments fall short, especially against complex, aggressive tumors.In this episode of the Smart Biotech Scientist Podcast, host David Brühlmann welcomes Jun Yung Woo, Co-Founder of AGEM Bio, who offers an in-depth look at the science and strategy behind engineered mesenchymal stem cells (MSCs), with a focus on why glioblastoma is the right proving ground for the platform.Topics discussed:Why glioblastoma is the right Phase I indication: infiltrative growth, immunosuppression, and STING pathway deficiencies that make GBM uniquely suited to the platform (02:43)The surgical workflow: intracavity MSC delivery during tumor resection, oral 5-FC administration, and how engineered cells act as local bioreactors in the resection cavity (04:05)Mechanisms by which engineered MSCs target heterogeneous and invasive tumors through shared vulnerabilities rather than antigen recognition (05:58)Overcoming immune rejection with allogeneic therapies and the unique immunological profile of MSCs (07:32)Manufacturing and scale-up: addressing donor variability, GMP production, and building a reproducible process (09:16)Why GMP manufacturing should be designed in from the earliest stages of research (10:50)Beyond glioblastoma: expanding the platform to other solid tumors, regenerative medicine, and chronic inflammatory disease (11:27)Strategies for international trial expansion and partnerships beyond Singapore (12:41)Reframing MSCs from stem cell therapy to programmable delivery platform: the MSC 2.0 thesis (14:10)Smart insight: The shift Jun Yung articulates is from treating stem cells as the therapy to treating them as programmable therapeutic vehicles. Once you can reliably engineer, manufacture, and preserve their function, the limitation is no longer what the cell naturally does. It becomes what biology you can encode into it. Glioblastoma is the proving ground, and the platform's reach extends to liver cancers, sarcomas, peritoneal malignancies, and chronic inflammatory disease.These episodes expand on the same themes of MSC biology, cell engineering, and the challenges of scaling consistent, functional cell therapies:Episodes 179 - 180 : How Mesenchymal Stromal Cells Are Transforming Care for Diabetes and Autoimmune Diseases with Lindsay DaviesEpisodes 253 - 254: How to Source, Manufacture, and Scale the Earliest Stem Cells for Allogeneic Cell Therapy Without Ethical Barriers with Yuta LeeEpisodes 125 - 126: How to Enhance Cell Engineering Using Mechanical Intracellular Delivery with Armon ShareiEpisodes 129 - 130: Revolutionizing Cell Therapy Manufacturing: Reducing Costs to Reach More Patients with Jason FosterConnect with Jun Yung Woo:LinkedIn: www.linkedin.com/in/junyungwooAGEM Bio website: www.agem.bioEmail: yung@agem.bioSupport the show

Guest: Dr. Jennifer Francis, Woodwell Climate Research CenterWhen we think about the Arctic, it's easy to picture a remote landscape of sea ice and polar bears. But what happens in the far north doesn't stay there. As the Arctic continues to warm at an unprecedented pace, scientists are uncovering how those changes may be influencing weather patterns across the Northern Hemisphere—from prolonged heat waves and persistent droughts to heavy rainfall and unusual swings in the jet stream. Today on Weather Geeks, we're joined by atmospheric scientist Dr. Jennifer Francis, whose pioneering research has helped shape our understanding of the connection between Arctic climate change and the behavior of the jet stream. We'll explore why the Arctic is warming so rapidly, how those changes can ripple through the atmosphere, and what they may mean for the persistent weather patterns we've seen in recent years—including the extreme heat that has gripped much of Europe this summer.Chapters00:00 Dr. Jennifer Francis's background and interest in weather05:22 Jet stream patterns and their role in extreme weather13:21 Break 114:31 Mechanisms of Arctic amplification and feedbacks22:57 Stratospheric polar vortex and winter weather effects25:04 Break 225:58 Summer jet stream behavior and climate connections32:08 Ocean heat waves and their influence on jet stream patterns34:33 Current research and future challenges in Arctic climate studies37:06 Closing remarks and resourcesResourcesWoodwell Climate Research Center - https://www.woodwellclimate.org/Jennifer Francis - Research Profile - https://www.woodwellclimate.org/our-scientists/jennifer-francis/Clausius-Clapeyron Relationship - https://en.wikipedia.org/wiki/Clausius%E2%80%93Clapeyron_relation Guest linksTwitter - https://x.com/WoodwellClimate https://x.com/JFrancisClimateResearch Center - https://www.woodwellclimate.org/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In today's video I discuss my favorite mechanisms in new-to-me games and expansions so far in 2026.   https://youtu.be/7pLyT7R1iyo

Broadcast from KSQD, Santa Cruz on 7-09-2026: Researchers refined a technique to reverse skin cell aging by about 30 years while preserving cellular identity. Exposing adult fibroblasts to Yamanaka factors—stopping before full reversion to pluripotent stem cells,reset the epigenetic clock and gene expression patterns to resemble much younger cells. The rejuvenated fibroblasts produced significantly more collagen, migrated faster to close artificial wounds, and showed reversal of gene expression patterns associated with Alzheimer's and cataracts. Since long-term epidemiologic data doesn't yet exist, Dr. Dawn follows up on last week's vaping question by exploring cancer mechanisms. Vaping aerosols impair DNA repair fidelity while triggering IL-6, IL-8, and TNF-alpha secretion. Nicotine-derived nitrosamines, reactive carbonyls (formaldehyde, acetaldehyde, acrolein) are generated when propylene glycol and vegetable glycerin are heated. Upregulated cytochrome P450 enzymes convert precarcinogens like benzopyrene into carcinogens. Mice exposed for 54 weeks developed lung adenocarcinomas in 22% and precancerous bladder hyperplasia in 57%, with markers matching those show predict lung cancer years before diagnosis. The Mexican Biobank—which includes over 40,000 samples from all 31 Mexican states revealed dramatic regional variation in drug-metabolism genes driven by Indigenous ancestry. In Chiapas, nearly 40% of the population carries two copies of a CYP2D6 variant reducing fentanyl metabolism, versus just 10% in Sinaloa. The SLCO1B1 variant hindering statin metabolism is found in over 15% of Yucatán residents., where 8 million Mexicans take statins. Dr. Dawn discusses both the promise and potential dark side of population genetic testing, including UK plans to genotype all children at birth for inborn errors of metabolism. Dr. Dawn briefly revisits the recent Indian study showing conch-shell blowing reduces sleep apnea by 34%, comparing it to earlier didgeridoo research, both of which strengthen airway muscles through forced-blowing exercises. A caller from Capitola recovering from non-Hodgkin's lymphoma near the L5 nerve asks about Japanese Kampo medicine formulas (Goshajinkigan, Yokukansan) for post-treatment nerve pain. Dr. Dawn suggests the pain likely originates from scar tissue tethering the nerve, and recommends consulting the Oriental Medicine Doctor program at Five Branches in Santa Cruz where faculty can advise on herbal formulas that trace back thousands of years through cultural exchange between China and Japan. Dr. Dawn explains Lp(a):lipoprotein(a), a small protein string attached to LDL particles that promotes clumping and clotting, is a genetically-determined coronary artery disease and stroke risk factor invisible to standard lipid panels. Levels of 250 particles double coronary risk and 350 particles triple it. Less than 75 is normal. Two new pharmaceutical strategies are in development to reduce Lp(a) : antisense oligonucleotides (single-stranded RNA that recruits RNase H to cleave target mRNA) and small interfering RNA (double-stranded RNA that triggers destruction of matching mRNA). Pelacarsen, a monthly injection in Phase 3 trials, reduces Lp(a) by 80%. These gene-silencing platforms open therapeutic possibilities for previously undruggable orphan diseases. Vitamin K2 is produced in the gut microbiome. MK-4 is most common in humans. Dr. Dawn recommends MK7 for stabilizing coronary calcium plaques and directing calcium into bone. A study of hepatitis B and C patients found MK4 to be protective in hepatocellular carcinoma. HCC developed in 2 of 21 MK-4-treated patients versus 9 of 19 controls, with a risk ratio of 0.2. MK-4 activates protein kinase A in vitro, inhibits HCC invasiveness, and restores apoptosis signaling that cancer cells normally block. Dr. Dawn recommends a couple milligrams of MK-4 daily for anyone with cirrhosis or prior hepatitis B or C infection.

Do your migraines seem to flare up as temperatures rise? Summer heat can place unique stress on the migraine brain, often triggering symptoms long before the pain begins.In this episode of Migraine Heroes Podcast, host Diane Ducarme explains how heat, dehydration, and sudden temperature shifts can impact migraine sufferers differently—and what you can do to stay one step ahead.You'll discover: ☀️ Five early clues that summer heat may be contributing to your migraine attacks ☀️ Why hot weather, fluid loss, and temperature fluctuations can affect the migraine brain so strongly ☀️ Simple ways to protect yourself from heat-related migraines and enjoy the season with greater confidenceUnderstanding your body's early signals can help you take action before a migraine fully develops. This episode offers practical insights to help you navigate warmer months with fewer disruptions and more peace of mind.

Dr. Martha Muñoz is an Assistant Professor in the Department of Ecology and Evolutionary Biology at Yale University. Martha is an evolutionary biologist who is working to better understand how and why evolution proceeds unevenly across the tree of life. Some features and branches of organisms evolve really quickly, while others remain inert or nearly inert for millions of years. Martha's research is uncovering the mechanisms underlying this phenomenon, and she has discovered that behavior is a key architect of evolution. For Martha, nature is a wonderful source of peace and inspiration for her research. When she's not working, she enjoys exploring the outdoors, hiking, seeing amazing views, and observing wildlife. She also spends her free time reading, going to museums, and visiting her family in New York City. She received her B.A. in biology from Boston University. Afterwards, Martha worked as a Fulbright Research Scholar at the National Museum of Natural Sciences in Madrid, Spain. She was awarded her Ph.D. in Organismic & Evolutionary Biology from Harvard University. Next, Martha conducted postdoctoral research in the Research School of Biology at The Australian National University and subsequently the Department of Biology at Duke University. Prior to accepting her current position at Yale University, Martha served on the faculty in the Department of Biological Sciences at Virginia Tech. Martha has received numerous awards and honors, including the Boston University Department of Biology's Distinguished Alumni 'Rising Star' Award, and a Young Investigator Award from the American Society of Naturalists. She was also named a 'Scientist to Watch' by The Scientist Magazine in 2019. In our interview, Martha shares more about her life and science.

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Insomnia and depression are two serious and debilitating conditions. Insomnia on its own is linked to an increase in suicide risk, and insomnia can also exacerbate the severity of depression.Andrea Goldstein-Piekarski, assistant professor in the department of psychiatry and behavioral sciences at Stanford, and Adam Krause, post-doctoral research fellow in Stanford's psychiatry department, are two of the authors of a recent study in the journal Neuropsychopharmacology. Cognitive behavioral therapy for insomnia, or CBTI, is the gold standard for treating insomnia, and it's been shown to relieve depressive symptoms as well.Read the full study here: https://www.nature.com/articles/s41386-026-02431-0 Hosted on Acast. See acast.com/privacy for more information.

In this episode, my guest is Dr. Glen Jeffery, PhD, a professor of neuroscience at University College London's Institute of Ophthalmology and a leading expert on how light interacts with mitochondria to shape health and aging. Today, he discusses how red and near-infrared light penetrate deep into the body and improve mitochondrial function and overall health. We also discuss how detrimental modern indoor life has become and why expensive red light panels are likely unnecessary and possibly harmful.By the end, you'll understand sunlight as a biological input your body evolved to depend on and the low-cost, practical steps you can take to get more of it.FULL SHOW NOTES HERE: https://l1nk.dev/bjuu235 Sponsor: Shadowmap  https://app.shadowmap.org/?ref=jonathan&discount=JONATHANJ Code: JONATHANJ   Sponsor: Ra Opticshttps://www.raoptics.com/JONATHANJ Code: JONATHANJ About this guest:Academic Profile: https://profiles.ucl.ac.uk/7465 Google Scholar: https://scholar.google.com/citations?user=UYlObKkAAAAJ&hl=en LinkedIn: https://www.linkedin.com/in/glen-jeffery-441a2b1b/ Timestamps:00:16 Intro02:46 Dr. Glen Jeffery03:14 Love for Science, Undergraduate04:24 Tiina Karu, Photobiomodulation Origins, Mechanisms 06:14 Mechanisms, Cytochrome C Oxydase, Nanowater, Electron Flow10:56 Cytochrome C Oxydase, Extra-Pineal Melatonin, Oxidative Stress12:45 Gerald Pollack, Exclusion Zone (EZ) Water13:45 Red/IR Light Passes Through the Human Body; Optics18:09 Red Light On Fruit Flies; Lifespan, ATP Production21:15 Human Epidemiology; Sunlight, Lifespan, All-Cause Mortality22:35 Sponsor: Shadowmap23:30 Features and Benefits of Shadow Map25:02 Incandescents, lifespan, and more25:02 Incandescent Light Produces the Oldest Flies; Broad Band IR on Lifespan25:48 Incandescent Light Bulbs, Vision 28:19 Evolutionarily Conserved Mitochondria29:03 Long-Wavelength Light & Blood Glucose; Mitochondria32:50 Unpublished CGM Data; Long-Wavelength Light & Blood Glucose36:57 Are Red Light Panels Harmful?; Light Intensities, Precautions, Mitigations43:56 Why Do We See Beneficial Effects From Long-Wavelength Therapy? 46:43 Short-Wavelength Blue Light, Mitochondria, Mechanism49:08 The Built Environment, Actionable Steps 52:24 Sponsor: Ra Optics54:24 Flicker55:24 Retinal Health, Blue Light, Red/IR Light59:09 Clinical Trial for Mitochondrial Disease; Ptosis, Red Light01:02:31 Biophotons, Mitochondrial Communication, Red/NIR on Biophotons 01:13:54 Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Social Media, Substack Newsletter

Please visit answersincme.com/MRQ860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Alexandra K. Golant, MD; Peter Lio, MD, FAAD; and Lakshi Aldredge, MSN, ANP-BC, DCNP, FAANP. In this activity, experts in dermatology discuss the OX40L pathway and its potential role in the treatment of moderate-to-severe atopic dermatitis. Upon completion of this activity, participants should be better able to: Identify the rationale for targeting the OX40/OX40 ligand (OX40L) pathway in the treatment of moderate-to-severe atopic dermatitis (AD); Assess the evidence on efficacy outcomes and safety profiles of the emerging OX40/OX40L inhibitors in AD, including quality of life (QoL) impact; Integrate QoL assessments into shared decision-making with patients who have moderate or severe AD; and Outline strategies for enhancing the multidisciplinary management of moderate-to-severe AD.

Please visit answersincme.com/MRQ860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Alexandra K. Golant, MD; Peter Lio, MD, FAAD; and Lakshi Aldredge, MSN, ANP-BC, DCNP, FAANP. In this activity, experts in dermatology discuss the OX40L pathway and its potential role in the treatment of moderate-to-severe atopic dermatitis. Upon completion of this activity, participants should be better able to: Identify the rationale for targeting the OX40/OX40 ligand (OX40L) pathway in the treatment of moderate-to-severe atopic dermatitis (AD); Assess the evidence on efficacy outcomes and safety profiles of the emerging OX40/OX40L inhibitors in AD, including quality of life (QoL) impact; Integrate QoL assessments into shared decision-making with patients who have moderate or severe AD; and Outline strategies for enhancing the multidisciplinary management of moderate-to-severe AD.

Please visit answersincme.com/MRQ860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Alexandra K. Golant, MD; Peter Lio, MD, FAAD; and Lakshi Aldredge, MSN, ANP-BC, DCNP, FAANP. In this activity, experts in dermatology discuss the OX40L pathway and its potential role in the treatment of moderate-to-severe atopic dermatitis. Upon completion of this activity, participants should be better able to: Identify the rationale for targeting the OX40/OX40 ligand (OX40L) pathway in the treatment of moderate-to-severe atopic dermatitis (AD); Assess the evidence on efficacy outcomes and safety profiles of the emerging OX40/OX40L inhibitors in AD, including quality of life (QoL) impact; Integrate QoL assessments into shared decision-making with patients who have moderate or severe AD; and Outline strategies for enhancing the multidisciplinary management of moderate-to-severe AD.

Kennst du das Gefühl, völlig erschöpft zu sein – und trotzdem nicht abschalten zu können? Der Körper ist müde, aber der Kopf macht Überstunden. Gedanken kreisen, der Schlaf kommt nicht und selbst kleine Dinge bringen uns aus dem Gleichgewicht. In dieser Folge sprechen Leon und Atze über Hyperarousal – einen Zustand innerer Alarmbereitschaft, den viele Menschen kennen. Warum springt unser innerer Rauchmelder manchmal schon bei Wasserdampf an? Weshalb bleiben manche Menschen ständig wachsam, gereizt oder angespannt? Und natürlich stellt sich die wichtigste Frage: Wie schaffen wir es, den Alarm wieder leiser zu drehen? Eine Folge über innere Unruhe, den Sinn unserer Alarmsysteme und die Kunst, wieder zur Ruhe zu finden. Fühlt euch gut betreut Leon & Atze Instagram: https://www.instagram.com/leonwindscheid/ https://www.instagram.com/atzeschroeder_offiziell/ Mehr zu unseren Werbepartnern findet ihr hier: https://linktr.ee/betreutesfuehlen Tickets: Atze: https://www.atzeschroeder.de/#termine Leon: https://leonwindscheid.de/tour/ Quellen: Bresser, T., Siemon, R., Rösler, L., Blanken, T. F., Sophie, & van Someren, E. J. W. (2026). Hyperarousal transdiagnostically dissected: Different dimensions characterize mood, anxiety, insomnia, posttraumatic stress and attention deficit hyperactivity disorders. eClinicalMedicine, 0(0), Article 103810. https://doi.org/10.1016/j.eclinm.2026.103810 Kendall, B. Tired yet wired. Beth Kendall. https://www.bethkendall.com/blog/tired-yet-wired Kühnel-Pfetzing, A. (2025). Stress und Hyperarousal. In H. Peter, T. Penzel, J. H. Peter, & J. G. Peter (Eds.), Enzyklopädie der Schlafmedizin. Springer. https://doi.org/10.1007/978-3-662-65186-5_212 Mastroianni, A. So you wanna de-bog yourself. Experimental History. https://www.experimental-history.com/p/so-you-wanna-de-bog-yourself McLaughlin, K. A., & Lambert, H. K. (2017). Child trauma exposure and psychopathology: Mechanisms of risk and resilience. Current Opinion in Psychology, 14, 29–34. https://doi.org/10.1016/j.copsyc.2016.10.004 Nesse, R. M. (2005). Natural selection and the regulation of defenses: A signal detection analysis of the smoke detector principle. Evolution and Human Behavior, 26(1), 88–105. https://doi.org/10.1016/j.evolhumbehav.2004.08.002 Psychology Today. (2026, January). How to stop worrying about things you can't control. https://www.psychologytoday.com/us/blog/hack-your-anxiety/202601/how-to-stop-worrying-about-things-you-cant-control Reddit. (2025). What does hypervigilance feel like to you? r/CPTSD. https://www.reddit.com/r/CPTSD/comments/1mqzkrc/what_does_hypervigilance_feel_like_to_you/ Riemann, D., Spiegelhalder, K., Feige, B., Voderholzer, U., Berger, M., Perlis, M., & Nissen, C. (2010). The hyperarousal model of insomnia: A review of the concept and its evidence. Sleep Medicine Reviews, 14(1), 19–31. https://doi.org/10.1016/j.smrv.2009.04.002 Reaktion: Julia Ditzer Produktion: Murmel Productions

In this episode, Joe and Austin explore the neuroscience of anxiety, the role of supplements, and practical strategies for managing anxiety through neuroplasticity and acceptance.Chapters00:00 Introduction and Personal Reflections02:02 Understanding Anxiety and Supplementation06:00 Neuroplasticity and Its Role in Anxiety11:47 The Mechanisms of Exposure Therapy18:00 Practical Strategies for Managing Anxiety23:57 The Role of Acceptance in Anxiety Management31:18 Embracing Anxiety as a Tool for Growth34:47 Understanding Anxiety: Normal vs. Disorder38:23 The Role of Supplements in Managing Anxiety46:07 Awareness and Acceptance: Key to Overcoming Anxiety59:14 Gradual Exposure: The Path to Resilience

What if one of the most important health crises affecting men today wasn't being caused by aging, but by the environment we live in? In this eye-opening solo episode, Darin Olien investigates the alarming decline in testosterone levels, fertility, and reproductive health among men worldwide. Drawing on decades of research, epidemiological studies, environmental science, endocrinology, and public health data, Darin examines the growing evidence connecting endocrine-disrupting chemicals, microplastics, sleep deprivation, chronic stress, poor lifestyle habits, and environmental toxins to declining testosterone levels across generations. From BPA, phthalates, atrazine, PFAS, and microplastics to sleep quality, circadian rhythms, cholesterol metabolism, cortisol regulation, and natural testosterone-supporting strategies, this episode explores what may be one of the most underreported public health issues of our time—and what men can do to take control of their health today.     What You'll Learn Why testosterone levels have been declining for decades The startling research on global sperm count decline How endocrine-disrupting chemicals interfere with hormone production Why BPA and phthalates may disrupt testosterone synthesis The role of atrazine, PFAS, and environmental toxins How chronic stress diverts resources away from testosterone production Why sleep may be the most important testosterone intervention The connection between cholesterol and hormone production How microplastics are being found throughout the human body The surprising relationship between statins and testosterone levels Natural lifestyle strategies that support healthy hormone production Practical steps to reduce environmental exposure and improve health     Chapters 00:00:00 – Welcome to SuperLife 00:00:33 – Sponsor: Fatty15 and cellular health 00:04:17 – The testosterone collapse explained 00:04:51 – Testosterone levels have been declining for decades 00:06:03 – Global sperm count decline and accelerating trends 00:07:02 – Why treating symptoms misses the root cause 00:07:27 – The hidden public health crisis 00:08:03 – Why low testosterone isn't just about aging 00:09:12 – Why hormone health affects longevity 00:09:53 – Low testosterone and increased mortality risk 00:10:35 – Testosterone's role in metabolism and cardiovascular health 00:11:27 – Endocrine-disrupting chemicals and hormone disruption 00:12:44 – BPA and its effects on testosterone production 00:13:59 – Phthalates and their impact on hormone pathways 00:16:00 – Glyphosate, atrazine, and pesticide exposure 00:17:07 – PFAS and reproductive health concerns 00:17:55 – Environmental toxins and population-wide effects 00:18:11 – Sponsor: Shakeology 00:20:02 – Cholesterol and hormone production 00:20:53 – Chronic stress and cortisol dominance 00:21:45 – Actionable solutions begin 00:21:56 – Why sleep is essential for testosterone production 00:23:07 – How sleep deprivation rapidly lowers testosterone 00:23:21 – Light pollution and circadian disruption 00:23:41 – Foods and nutrients needed for hormone health 00:24:23 – Microplastics and testicular tissue 00:24:53 – Statins and unintended hormonal consequences 00:25:39 – A practical testosterone sovereignty protocol 00:25:48 – Water filtration and reducing toxic exposure 00:26:13 – Eliminating plastics and fragrance chemicals 00:26:35 – Why organic food matters 00:26:45 – Sunlight and vitamin D 00:27:05 – Magnesium, omega-3s, and iodine 00:27:26 – Pine pollen and natural androgen support 00:28:01 – Tongkat Ali and ashwagandha 00:28:48 – Strength training and lifestyle interventions 00:29:10 – Habits that naturally support testosterone 00:29:27 – Darin's approach to healthy aging 00:29:37 – Plants, herbs, and common sense 00:29:51 – Reclaiming your health and sovereignty 00:30:00 – Final thoughts and closing message     Thank You to Our Sponsors Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Shakeology: Get 15% off with code DARINO1BODI at Shakeology.com.     Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only $7.49/month at https://patreon.com/darinolien     Find More from Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness     Key Takeaway "The testosterone crisis may be about far more than aging. It may be a reflection of the modern environment itself—one increasingly saturated with endocrine-disrupting chemicals, chronic stress, poor sleep, circadian disruption, and toxic exposures. While many of these forces feel outside our control, the encouraging reality is that many of the most powerful interventions remain accessible: improving sleep, reducing toxic load, eating whole foods, getting sunlight, managing stress, exercising regularly, and reclaiming responsibility for our health. The goal isn't fear. The goal is awareness—and action."     Bibliography/Sources: The Decline — Primary Research Levine, H., Jørgensen, N., Martino-Andrade, A., et al. (2022). Temporal trends in sperm count: A systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries. Human Reproduction Update, 29(2), 157–176. https://doi.org/10.1093/humupd/dmac035 Lokeshwar, S. D., Patel, P., Fantus, R. J., et al. (2021). Decline in testosterone levels in men aged 15–40: Results from the National Health and Nutrition Examination Survey (NHANES), 1999–2016. World Journal of Urology, 39(2), 447–452. https://doi.org/10.1007/s00345-020-03227-1 Spital Clinic. (2026, March). Declining testosterone levels by generation. https://www.spitalclinic.com Travison, T. G., Araujo, A. B., O'Donnell, A. B., Kupelian, V., & McKinlay, J. B. (2007). A population-level decline in serum testosterone levels in American men. The Journal of Clinical Endocrinology & Metabolism, 92(1), 196–202. https://doi.org/10.1210/jc.2006-1375 Low Testosterone — Mortality & Disease Risk Muraleedharan, V., Marsh, H., Kapoor, D., Channer, K. S., & Jones, T. H. (2013). Testosterone deficiency is associated with increased risk of mortality and testosterone replacement improves survival in men with type 2 diabetes. European Journal of Endocrinology, 169(6), 725–733. https://doi.org/10.1530/EJE-13-0321 Shores, M. M., et al. (2006). Low testosterone associated with increased all-cause and cardiovascular mortality. Archives of Internal Medicine, 166(15), 1660–1665. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/410754 Yeap, B. B., Marriott, R. J., Dwivedi, G., et al. (2024). Associations of testosterone and related hormones with all-cause and cardiovascular mortality and incident cardiovascular disease in men. Annals of Internal Medicine. https://doi.org/10.7326/M23-2781 Endocrine Disrupting Chemicals Associations between endocrine-disrupting chemical exposure and fertility outcomes: A decade of human epidemiological evidence. (2024). PubMed Central (PMC12299029). https://pmc.ncbi.nlm.nih.gov/articles/PMC12299029/ Hayes, T. B., Haston, K., Tsui, M., et al. (2002). Herbicides: Feminization of male frogs in the wild. Nature, 419, 895–896. https://doi.org/10.1038/419895a Mechanisms of testicular disruption from exposure to BPA and phthalates. (2020). Journal of Clinical Medicine, 9(2), 471. https://pmc.ncbi.nlm.nih.gov/articles/PMC7074154/ Meeker, J. D., Calafat, A. M., & Hauser, R. (2014). Urinary phthalate metabolites and their biotransformation products: Predictors and temporal variability among men and women. Journal of Exposure Science & Environmental Epidemiology. https://www.sciencedaily.com/releases/2014/08/140814124330.htm Zhao, Q., et al. (2023). Male reproductive toxicity of microplastics: Head and tail of the sperm. Science of the Total Environment, 872, 162181. https://doi.org/10.1016/j.scitotenv.2023.162181 Zhong, B., et al. (2024). Mixed EDC exposure associated with reductions in testosterone and free androgen index. Scientific Reports. https://doi.org/10.1038/s41598-024-76972-z Cortisol, Stress & the HPG Axis Bielohuby, M., et al. (2012). Swiss military cadets prolonged stress study. Psychoneuroendocrinology. Preprints.org. (2025). Sleep deprivation: A modifiable cause. https://doi.org/10.20944/preprints202505.0580.v1 SiPhox Health. (n.d.). Summary of Journal of Clinical Endocrinology & Metabolism data. https://www.siphoxhealth.com Viau, V. (2002). Functional cross-talk between the hypothalamic-pituitary-gonadal and -adrenal axes. Journal of Neuroendocrinology, 14(6), 506–513. https://doi.org/10.1046/j.1365-2826.2002.00798.x Sleep & Testosterone Leproult, R., & Van Cauter, E. (2011). Effect of 1 week of sleep restriction on testosterone levels in young healthy men. JAMA, 305(21), 2173–2174. https://jamanetwork.com/journals/jama/fullarticle/1029127 Reiter, R. J., et al. (2021). Melatonin and male reproductive health: Relationship to oxidative stress, mitochondrial function, and Leydig cell protection. Endocrine. Tan, D. X., Hardeland, R., Manchester, L. C., et al. (2023). Melatonin as a pleiotropic antioxidant hormone. Journal of Pineal Research. Nutrition — Zinc, Vitamin D, Cholesterol Corona, G., et al. (2010). Statin therapy and testosterone levels in men: A systematic review. The Journal of Sexual Medicine. Daniell, H. W. (2002). Hypogonadism in men consuming sustained-action oral opioids. The Journal of Pain, 3(5), 377–384. https://doi.org/10.1054/jpai.2002.126790 Pilz, S., Frisch, S., Koertke, H., et al. (2011). Effect of vitamin D supplementation on testosterone levels in men. Hormone and Metabolic Research, 43(3), 223–225. https://doi.org/10.1055/s-0030-1269854 Prasad, A. S., Mantzoros, C. S., Beck, F. W., Hess, J. W., & Brewer, G. J. (1996). Zinc status and serum testosterone levels of healthy adults. Nutrition, 12(5), 344–348. https://doi.org/10.1016/S0899-9007(96)80058-X Natural Testosterone Support — Botanical Evidence Pine pollen impacts testosterone-related symptoms in men. (2024). ACMCR Case Reports, 14(5), 1–9. Chinnappan, S. M., George, A., et al. (2021). Effect of Eurycoma longifolia standardised extract Physta on testosterone levels in ageing males: A randomised, double-blind, placebo-controlled multicentre study. Food & Nutrition Research, 65. https://doi.org/10.29219/fnr.v65.5647 Lazarev, A., & Bezuglov, E. (2021). Testosterone boosters intake in athletes: Current evidence and further directions. Endocrines, 2(2), 109–120. https://doi.org/10.3390/endocrines2020011 Leisegang, K., et al. (2022). Eurycoma longifolia (Tongkat Ali) improves serum total testosterone in men. Food & Nutrition Research. https://pubmed.ncbi.nlm.nih.gov/36013514/ Leitão, A. E., et al. (2021). 6-month double-blind RCT: Eurycoma longifolia 200mg + concurrent training. Maturitas. https://doi.org/10.1016/j.maturitas.2020.10.005 Lopresti, A. L., Smith, S. J., et al. (2019). An investigation into the stress-relieving and pharmacological actions of an ashwagandha extract. Medicine, 98(37), e17186. https://doi.org/10.1097/MD.0000000000017186 Pandit, S., Biswas, S., Jana, U., De, R. K., Mukhopadhyay, S. C., & Biswas, T. K. (2016). Clinical evaluation of purified shilajit on testosterone levels in healthy volunteers. Andrologia, 48(5), 570–575. https://doi.org/10.1111/and.12482 Saden-Krehula, M., Tajic, M., & Kolbah, D. (1971). Testosterone, epitestosterone and androstenedione in the pollen of Scotch pine Pinus sylvestris L. Experientia, 27(1), 108–109. https://doi.org/10.1007/BF02137731 Wankhede, S., Langade, D., Joshi, K., et al. (2015). Examining the effect of Withania somnifera supplementation on muscle strength and recovery: A randomized controlled trial. Journal of the International Society of Sports Nutrition, 12, 43. https://doi.org/10.1186/s12970-015-0104-9

Episode 97: Cole Smith - Games that Combine 2 Mechanisms well - Top 5 Area Control Games - A Frame Job & Good FoodCanadian board game and graphic designer, Cole Smith, joins me to talk about his current published games, games that combine 2 mechanisms well, and his favorite mechanism, area control, games.00:00:00 Intro00:00:21 Get to Know Cole Smith and his gamesTanuki Sauros 3 Magi 00:05:58 The Journey of Game Design00:08:23 Cole's Favorite Mechanism or Game that inspires him00:14:42 Games that Blend 2 Well-Known Mechanics WellLost Ruins or ArnakDune ImperiumEndless Winter: PaleoamericansPatchworkCascadia and other Flatout line of gamesSaurosRumble NationRadlands 7 Wonders DuelSagrada Nokosu diceKing of TokyoThe Lord of the Rings: The Fellowship of the Ring - Trick Taking GameIliadTag TeamArcs00:33:32 Top 5 Area Control Games00:37:57 The King is Dead: Second Edition00:40:18 Rumble Nation00:41:46 Waddle00:44:35 Ankh: Gods of Egypt00:47:25 Marrakech00:50:50 Rumble Nation (Overlap)00:51:09 Sunrise Lane00:54:27 Scythe00:58:45 Foundations of Rome01:03:16 Root01:07:26 Patrician01:10:29 Honorable Mentions01:10:40 Big Boss01:12:59 Shackleton Base: A Journey to the Moon01:15:01 Ahoy01:16:02 Moment of Positivity01:20:09 Where can you find Cole?BGG Designer PageInstagram @Cole_Designs_Games01:21:24 Outro(Please note that these time stamps might not be accurate due to the use of dynamic ads.)You can flip your game night by picking up DNUP.https://www.dnup.game/en/Web: https://boardgamegeek.com/YouTube: https://www.youtube.com/@boardgamegeekTwitter: https://twitter.com/BoardGameGeekEmail: podcast@boardgamegeek.com

The episode opens with a welcome to the podcast and introductions to the panelists. It highlights their diverse expertise in mineral metabolism, applied nutrition, and industry insights. (00:00 – 02:38) The discussion begins with a deep dive into the mechanisms of mineral absorption, focusing on epithelial barriers and transporters. The panel discusses how minerals like magnesium are absorbed across the rumen wall. Moreover, they explore how antagonists interfere with absorption and introduce the concept of measuring bioavailability under field conditions. (04:35 – 10:13) From there, the conversation shifts to practical dairy nutrition strategies, including how to manage macro minerals and antagonists within the diet. The panel discusses the importance of water quality and alternative magnesium sources. Additionally, they share effective calcium strategies for supporting fresh cows and reducing metabolic challenges. (11:36 – 16:48) The panel then explores mineral interactions and balance, including the concept of mineral homeostasis and the role of skeletal calcium reserves. They challenge traditional thinking around calcium-to-phosphorus ratios. Furthermore, they examine key interactions between potassium, magnesium, and sodium that can impact absorption and overall animal health. (18:59 – 24:42) As the episode continues, the discussion turns to the future of agricultural research, including the growing role of genomics in shaping nutrient requirements. The panel also addresses ongoing challenges in funding and education. Additionally, they discuss the broader influence of policy and corporate investment on the direction of scientific research. (26:03 – 32:43) Attention then shifts to diagnostics and emerging tools, where the panel discusses biomarkers and enzyme-based approaches for tracking bioavailability. They also emphasize the importance of proper blood sampling timing. Additional topics include phosphorus binders, zeolite-based diets, and unanswered questions around the evolutionary role of magnesium. (33:48 – 38:34) The episode concludes with a focus on holistic mineral management, emphasizing the importance of integrating scientific understanding into practical feeding decisions. The panel shares final insights and key takeaways for improving mineral nutrition programs. In summary, they also support long-term dairy cow performance. (41:20 – 42:38) Please subscribe and share with your industry friends. Invite more people to join us at the Real Science Exchange virtual pub table. Please be sure to register for our upcoming Real Science Lecture Series webinars. Finally, if you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription. Then, email a picture to anh.marketing@balchem.com. Include your size and mailing address. As a result, we'll mail you a shirt.

Welcome to episode #1040 of Thinking With Mitch Joel (formerly Six Pixels of Separation). Long before artificial intelligence became the dominant business conversation, Sangeet Paul Choudary was helping leaders understand another profound shift in economic power: the rise of platforms. As the co-author of Platform Revolution, founder of Platform Thinking Labs, advisor to global corporations and governments, and a respected thinkers on digital business models, Sangeet has spent years studying how technology changes the sources of competitive advantage and reshapes entire industries. His latest book, Reshuffle - Who Wins When AI Restacks The Knowledge Economy, extends that work into the age of artificial intelligence, exploring what happens when the expertise, judgment and know-how that once lived inside individuals and organizations increasingly migrates into software systems. In this conversation, Sangeet explains why AI represents far more than a productivity upgrade. He argues that every major technological shift changes what is scarce, and when scarcity changes, value moves with it. Drawing on examples ranging from Kodak and Netflix to cloud computing, software platforms and global supply chains, he explores why some organizations adapt while others become trapped by the assumptions that made them successful in the first place. The discussion also examines the changing nature of economic power, the growing importance of digital sovereignty, the future of knowledge work, and the risks of assuming that today's business models will survive tomorrow's technological realities. Throughout the conversation, Sangeet offers a framework for understanding not just what AI can do, but how leaders can rethink their organizations, industries and careers when the foundations of value creation are being rewritten in real time. Enjoy the conversation… Running time: 1:00:47. Hello from beautiful Montreal. Listen and subscribe over at Apple Podcasts. Listen and subscribe over at Spotify. Please visit and leave comments on the blog - Thinking With Mitch Joel. Feel free to connect to me directly on LinkedIn. Check out ThinkersOne. Here is my conversation with Sangeet Paul Choudary. Reshuffle - Who Wins When AI Restacks The Knowledge Economy. Platform Thinking Labs. Platform Revolution. Follow Sangeet on X. Follow Sangeet on LinkedIn. Chapters: (00:00) - Introduction to Sangeet Chaudhary and Reshuffle. (02:51) - The Impact of Technological Shifts on Value Creation. (05:51) - Understanding Architectural Constraints in Business. (09:07) - The Role of Supply Chain in Innovation. (12:10) - AI's Influence on Software and Business Models. (14:56) - Navigating Uncertainty in AI Adoption. (18:04) - The Future of Economic Power and Sovereignty. (21:00) - Cultural Shifts in Power Dynamics. (23:53) - The Mechanisms of Change in AI and Business. (26:52) - The Balance of Sovereignty and Dominance. (29:46) - The Future of Work in an AI-Driven Economy. (32:44) - The Broader Implications of AI on Society. (36:40) - Conclusion and Reflections on Reshuffle.

Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition. Guest Links Dr. Milo Wolf's Links: Website/Coaching: Wolf Coaching App: MyoAdapt YouTube: Dr. Milo Wolf Instagram: @wolfcoach_ Timestamps 00:00 Intro and why warmups matter 00:46 Why warmups may be overrated for hypertrophy 03:21 General vs specific warmups and static vs dynamic stretching 04:41 Static stretching and short-term performance tradeoffs 07:25 Stretching and injury-prevention evidence 10:08 FIFA 11, strength training, plyometrics, and multi-part warmups 11:42 Why plyometrics can build resilience 15:55 Mechanisms: temperature, oxygen uptake, psychology, and neural readiness 18:16 Sports-team warmups, coaching logistics, and specificity 38:29 Nick's real warmup routine and Milo's reaction 49:20 Milo's default warmup recommendation 53:07 Pain, injury, and adjusting the approach  

In Part 3 of Detox in a Toxic World, we take a closer look at what “detox” actually means and how the body is already doing it every single day. This episode breaks down the body's major detox and elimination pathways, including the liver, gut, kidneys, lungs, skin, lymphatic system, and glymphatic system, and explains how these beautifully coordinated processes help clear hormones, waste products, and environmental compounds.We also walk through practical, evidence-based ways to support these natural detox mechanisms, including nutrition, hydration, movement, sweating, lymphatic support, sleep, mind-body medicine, and time in nature.Companion Guide: drmaryellawood.com/guides 

The Tenpenny Files – Jeff Brown shares his account of entering Canada's political inner circle and facing alleged surveillance, interception, suppression, and institutional pressure after trying to leave. The discussion examines power, censorship, media control, sovereignty, and the invisible systems Brown believes shape perception, isolate dissenters, and threaten individual freedom in modern political life...

Jason Jay Smart is a political adviser who has lived and worked in Ukraine, Moldova, Kyrgyzstan, Kazakhstan, Russia, and Latin America. Due to his work with the democratic opposition to Vladimir Putin, Smart was made persona non grata for life by Russia in 2010. Jason is a Special Correspondent at the Kyiv Post. It's the state of US support for Ukraine that we will discuss today.----------LINKS:https://jasonjaysmart.com/ https://www.kyivpost.com/authors/5 https://americanpoliticalservices.com/https://www.facebook.com/jasonjaysmarthttps://twitter.com/officejjsmart ----------SUPPORT THE CHANNEL:https://www.buymeacoffee.com/siliconcurtainhttps://www.patreon.com/siliconcurtainhttps://www.gofundme.com/f/scaling-up-campaign-to-fight-authoritarian-disinformation----------TRUSTED CHARITIES ON THE GROUND:Car4Ukrainehttps://car4ukraine.com/en-US/campaignsDzyga's Pawhttps://dzygaspaw.com/projectsSuperhumans - Hospital for war traumashttps://superhumans.com/en/UNBROKEN - Treatment. Prosthesis. Rehabilitation for Ukrainians in Ukrainehttps://unbroken.org.ua/Come Back Alivehttps://savelife.in.ua/en/Chefs For Ukraine - World Central Kitchenhttps://wck.org/relief/activation-chefs-for-ukraineUNITED24 - An initiative of President Zelenskyyhttps://u24.gov.ua/Serhiy Prytula Charity Foundationhttps://prytulafoundation.orgNGO “Herojam Slava”https://heroiamslava.org/----------PLATFORMS:Substack: https://substack.com/@siliconcurtainTwitter: https://twitter.com/CurtainSiliconLinkedin: https://www.linkedin.com/in/finkjonathan/Podcast: https://open.spotify.com/show/4thRZj6NO7y93zG11JMtqm----------

If you enjoy this episode, we're sure you will enjoy more content like this on The Occult Rejects.  In fact, we have curated playlists on occult topics like grimoires, esoteric concepts and phenomena, occult history, analyzing true crime and cults with an occult lens, Para politics, and occultism in music. Whether you enjoy consuming your content visually or via audio, we've got you covered - and it will always be provided free of charge.  So, if you enjoy what we do and want to support our work of providing accessible, free content on various platforms, please consider making a donation to the links provided below.  Thank you and enjoy the episode!Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Cash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejectsBibliographyThe Mechanics of Magick: Singing Bowls and the Ritual Physics of ResonanceCore Singing Bowl ResearchStanhope, Jessica, and Philip Weinstein. “The Human Health Effects of Singing Bowls: A Systematic Review.” Complementary Therapies in Medicine 51 (2020): 102412. Use for the honesty frame: promising findings around mental health and cardiovascular measures, but limited evidence and need for stronger study design.Cai, Yiqing, Guo-Yan Yang, Yibo Liu, Xiang-yun Zou, Heng Yin, Xinyan Jin, Xue-han Liu, Chenlu Wang, Nicola Robinson, and Jian-Ping Liu. “Therapeutic Effects of Singing Bowls: A Systematic Review of Clinical Studies.” Integrative Medicine Research 14, no. 2 (2025): 101144. Use for the newer clinical overview. Important correction: this appears as 101144, not 101176. Good for anxiety, depression, sleep quality, cognition, autistic behavior, and EEG-related outcomes while still keeping the evidence cautious.Lin, F. W., et al. “Effects of Tibetan Singing Bowl Intervention on Psychological and Physiological Health in Adults: A Systematic Review.” 2025. Useful as another recent review angle, especially for psychological health, physiological measures, HRV, and brainwave-related discussion. Keep it secondary behind Stanhope and Cai.Landry, Jayan Marie. “Physiological and Psychological Effects of a Himalayan Singing Bowl in Meditation Practice: A Quantitative Analysis.” American Journal of Health Promotion 28, no. 5 (2014): 306–309. Use for the controlled relaxation study: 51 participants, randomized crossover design, singing bowl exposure or silence before directed relaxation.Goldsby, Tamara L., Michael E. Goldsby, Mary McWalters, and Paul J. Mills. “Effects of Singing Bowl Sound Meditation on Mood, Tension, and Well-Being: An Observational Study.” Journal of Evidence-Based Complementary & Alternative Medicine 22, no. 3 (2017): 401–406. Use for reductions in tension, anger, fatigue, depressed mood, anxiety, and stress after singing bowl meditation. Good, but frame as observational, not definitive.Rio-Alamos, Cristina, et al. “Acute Relaxation Response Induced by Tibetan Singing Bowl Sounds: A Randomized Controlled Trial.” European Journal of Investigation in Health, Psychology and Education 13, no. 2 (2023): 317–328. Use for Tibetan singing bowl treatment compared with progressive muscle relaxation and a waiting-list control in anxious nonclinical adults.Walter, Nina, et al. “Neurophysiological Effects of a Singing Bowl Massage.” Medicina 58, no. 5 (2022): 594. Use for EEG, ECG, and respiration during singing bowl massage; the authors interpret the results as a shift toward a more mindful or meditative state.Goldsby, Tamara L., et al. “Mood, Emotional, and Spiritual Well-Being Interrelationships.” Religions 13, no. 2 (2022). Useful follow-up for spiritual well-being, emotional interpretation, and how people understand sound-healing experiences.Sound, Anxiety, HRV, and Brainwave CautionMallik, Adiel, and Frank A. Russo. “The Effects of Music & Auditory Beat Stimulation on Anxiety: A Randomized Clinical Trial.” PLOS ONE 17, no. 3 (2022): e0259312. Use this carefully for the broader point that sound-based treatments can reduce somatic and cognitive state anxiety. Do not use it as proof that singing bowls automatically entrain brainwaves.Ingendoh, Ruth Maria, Ella S. Posny, and Angela Heine. “Binaural Beats to Entrain the Brain? A Systematic Review of the Effects of Binaural Beat Stimulation on Brain Oscillatory Activity, and the Implications for Psychological Research and Intervention.” PLOS ONE 18, no. 5 (2023): e0286023. Very useful caution source. Use it when warning against overclaiming “brainwave entrainment” and frequency-healing claims.Vilímek, et al. 2022. Low-frequency sound / HRV / vibroacoustic-related research. Use cautiously if you want to discuss low-frequency vibration, body sensation, and autonomic response. I'd keep this as a secondary source unless you want a dedicated paragraph on vibroacoustics.Physics, Resonance, and CymaticsTerwagne, Denis, and John W. M. Bush. “Tibetan Singing Bowls.” Nonlinearity 24, no. 8 (2011): R51–R66. Use for the physics section: wall vibrations, water-surface waves, Faraday-wave effects, droplet motion, and the visible demonstration of resonance.Jenny, Hans. Cymatics: A Study of Wave Phenomena and Vibration. Newmarket, NH: MACROmedia, 2001. Use carefully for visual sound-pattern history. Good for imagery and occult imagination, but don't overuse it as clinical proof.Rossing, Thomas D. The Science of Sound. 3rd ed. San Francisco: Addison Wesley, 2002. Useful general acoustics source for resonance, overtones, vibration, sound waves, and instrument physics.Sound Baths, Wellness Culture, and Modern RitualSobo, Elisa J. “Sound Baths, Trauma Talk, and the Wellness Paradox in the USA.” Medical Anthropology 43, no. 5 (2024): 367–382. Excellent for the modern sound-bath/wellness-culture angle, especially trauma language, nervous-system talk, ritual performance, and how providers frame sound baths.Sobo, Elisa J. “A Beginner's Guide to Sound Baths — What They Are, How to Choose a Good One and What the Research Shows.” The Conversation (2024). Useful for accessible show-note language and ethical/practical framing.Sobo, Elisa J. “Healing Vibrations.” Anthropology News 64, no. 5 (2023): 28–32, 49. Good anthropology/public-facing source for sound healing and wellness culture.Tibetan Singing Bowls, History, and Cultural CommodificationGrimes, Samuel. “Where Did ‘Tibetan' Singing Bowls Really Come From?” Tricycle (2020). Use for the contested-history section. Strong source for questioning popular origin stories around “Tibetan” singing bowls.Joffe, Ben. “Anthropology and Tibetan Buddhism / Cultural Commodification / Tibetan Mystique.” 2015. Use for the larger argument about how Tibetan/Himalayan aura gets packaged in Western spiritual markets. Good support for the “Tibet as imagined storehouse of hidden wisdom” point.Scheidegger, Daniel A. “Tibetan Ritual Music.” Use for actual Tibetan Buddhist ritual sound: bells, cymbals, long horns, drums, chant, and liturgical soundscape. This helps separate real Tibetan ritual sound from overblown modern singing-bowl mythology.Lopez, Donald S. Prisoners of Shangri-La: Tibetan Buddhism and the West. Chicago: University of Chicago Press, 1998. Excellent support for Western romanticization of Tibet.Bishop, Peter. The Myth of Shangri-La: Tibet, Travel Writing, and the Western Creation of Sacred Landscape. Berkeley: University of California Press, 1989. Very useful for the “Tibet as fantasy geography” angle.Ritual, Sound, and Religious ExperienceEliade, Mircea. Shamanism: Archaic Techniques of Ecstasy. Princeton: Princeton University Press, 1964. Use carefully. Good for altered-state technologies and ritual sound/trance, but don't treat it as the final word on shamanism.Rouget, Gilbert. Music and Trance: A Theory of the Relations Between Music and Possession. Chicago: University of Chicago Press, 1985. Excellent for sound, music, trance, possession, rhythm, and ritual performance.Becker, Judith. Deep Listeners: Music, Emotion, and Trancing. Bloomington: Indiana University Press, 2004. Strong source for deep listening, music, emotion, trance, and the body.Husserl, Edmund. On the Phenomenology of the Consciousness of Internal Time. Useful if you want to get philosophical about tone, decay, waiting, and how sound reveals time.Ihde, Don. Listening and Voice: Phenomenologies of Sound. Albany: SUNY Press, 2007. Good for sound as experience, listening, voice, and embodied perception.Placebo, Meaning Response, and Healing RitualMoerman, Daniel E. Meaning, Medicine and the “Placebo Effect.” Cambridge: Cambridge University Press, 2002. Use for “meaning response” instead of treating placebo as “fake.”Benedetti, Fabrizio. Placebo Effects: Understanding the Mechanisms in Health and Disease. Oxford: Oxford University Press, 2009. Useful for placebo mechanisms, expectation, physiology, and therapeutic context.Kaptchuk, Ted J., and Franklin G. Miller. “Placebo Effects in Medicine.” New England Journal of Medicine 373 (2015): 8–9. Good short medical source for placebo effects as real psychobiological phenomena.Csordas, Thomas J. The Sacred Self: A Cultural Phenomenology of Charismatic Healing. Berkeley: University of California Press, 1994. Useful for healing, embodiment, ritual, and religious experience.Embodied Cognition, Extended Mind, and Ritual ToolsClAlso want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. A

The South Carolina Supreme Court reversed Alex Murdaugh's murder convictions on procedural grounds — finding the trial judge misapplied the burden of proof, violated Rule 606(b) by probing jurors' mental processes, and credited testimony the court deemed inadmissible. A retrial has been ordered under significantly narrowed evidentiary parameters. The central unknown heading into that proceeding is Buster Murdaugh.Buster testified for the defense at the original trial. He has since reportedly distanced himself from Alex — minimal prison contact, a quiet marriage, and according to sources, open anger about the retrial. He has allegedly characterized his father as a "selfish old man." Jennifer Coffindaffer and retired FBI behavioral analyst Robin Dreeke examine whether the prosecution can leverage that fracture and what legal mechanisms exist to compel testimony about private conversations between father and son after the killings. Coffindaffer also identifies a structural weakness in the State's family annihilation theory: if Alex allegedly killed to eliminate exposure, the survival of Buster undermines the logic of the motive as constructed.Defense attorney and former prosecutor Eric Faddis provides the comprehensive legal breakdown. The Supreme Court ruled twelve and a half hours of financial crimes testimony was excessive and ordered sharp limitations at retrial. Faddis maps what survives — the CFO confrontation and the opposing attorney's hearing that form the motive timeline — and what gets excluded. He addresses the unresolved evidentiary challenges carried forward from the direct appeal: the firearm analysis, the blue raincoat, the gunshot residue testimony, and the iPhone demonstration. He also examines the retrial complications — Alex Murdaugh's locked-in testimony, Becky Hill's perjury conviction as a defense weapon, and the venue and jury selection challenges both sides face in a case with this level of public saturation.Join Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1Instagram https://www.instagram.com/hiddenkillerspod/Facebook https://www.facebook.com/hiddenkillerspod/Tik-Tok https://www.tiktok.com/@hiddenkillerspodX Twitter https://x.com/TrueCrimePodThis publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.#AlexMurdaugh #BusterMurdaugh #MurdaughRetrial #EricFaddis #BeckyHill #SCSupremeCourt #JenniferCoffindaffer #RobinDreeke #HiddenKillers #TrueCrime

PREVIEW for Later Today: Henry Sokolski. Henry Sokolski discusses the NPT review, warning against granting enrichment rights to Middle Eastern nations and emphasizing the need for stronger international enforcement mechanisms.

Stay informed on current events, visit www.NaturalNews.com  - Backlash Against AI Data Centers (0:12) - Ethical and Legal Challenges of Data Centers (3:25) - Government and Corporate Influence on Data Center Locations (7:53) - Impact of AI Surveillance and Authoritarian Governments (10:08) - Famine and Fuel Shortages in America (12:22) - Human Migration and Economic Instability (44:47) - Cannibalism and Depopulation Techniques (1:05:30) - Economic and Social Implications of Depopulation (1:13:23) - Historical Context of Famines and Government Control (1:20:01) - Mechanisms of Creating Famines (1:23:29) - Historical Figures and Famine Preparedness (1:27:08) - Impact of Infrastructure Destruction (1:31:38) - Globalist Agendas and Human Resources (1:34:27) - Vulnerabilities of Mega Cities and Regions (1:45:42) - Grand Strategic Level and Synthetic Countries (1:47:58) - Future Vision of Global Elites (1:57:35) - Final Thoughts and Recommendations (2:02:43) Watch more independent videos at http://www.brighteon.com/channel/hrreport  ▶️ Support our mission by shopping at the Health Ranger Store - https://www.healthrangerstore.com ▶️ Check out exclusive deals and special offers at https://rangerdeals.com ▶️ Sign up for our newsletter to stay informed: https://www.naturalnews.com/Readerregistration.html Watch more exclusive videos here:

What if loneliness isn't just an emotion… but one of the most dangerous biological threats to your health? In this deeply personal and scientifically explosive solo episode, Darin opens up about something he recently realized in his own life: despite being surrounded by people, he was lonely. But what began as an emotional realization quickly became a deep dive into some of the most shocking research he's ever uncovered, showing that chronic loneliness may increase the risk of heart disease, dementia, cancer, autoimmune dysfunction, accelerated aging, and early death. From inflammatory gene expression and cortisol dysregulation to oxytocin, vulnerability, and the collapse of real human connection in the digital age, this episode reveals why loneliness may be the most overlooked "fatal convenience" of modern life, and how vulnerability may be the medicine. What You'll Learn Why loneliness is a biological crisis, not just an emotional feeling The shocking link between loneliness and heart disease, dementia, and early death Why the quality of your relationships is the #1 predictor of long-term health How loneliness activates inflammatory genes inside your body The role of cortisol, sleep disruption, and chronic stress in social isolation Why social media and "surface-level connection" are replacing real intimacy The connection between loneliness and Alzheimer's disease How oxytocin and genuine connection reduce inflammation Why vulnerability is the gateway to meaningful relationships Practical ways to create deeper connection starting today Chapters 00:00:33 – Sponsor: the truth about the exploding NAD supplement market 00:01:04 – Why supplement verification and transparency matter 00:02:17 – Opening: Darin admits something deeply personal 00:02:30 – "I realized recently… I'm lonely" 00:02:37 – The difference between being surrounded by people vs being truly known 00:03:06 – Loneliness as a biological experience, not just an emotional one 00:03:27 – The hidden risks: heart disease, dementia, cancer, early death 00:03:45 – Why this is not fringe science 00:04:13 – The most important predictor of long-term health 00:04:34 – Why relationship QUALITY matters more than quantity 00:05:06 – The global loneliness epidemic 00:05:11 – U.S. Surgeon General advisory on loneliness 00:05:39 – Loneliness declared a public health crisis 00:06:02 – 50% of Americans report measurable loneliness 00:06:22 – "A generational collapse of connection" 00:06:30 – 29% of adults have no close friends 00:06:40 – Face-to-face interactions dramatically declining 00:07:01 – The UK, Japan, and Australia loneliness crisis initiatives 00:07:32 – The paradox: hyperconnected but deeply isolated 00:08:04 – Loneliness as a biological alarm signal 00:08:31 – What loneliness actually looks like in modern life 00:08:42 – The lonely CEO, the unseen mother, the isolated social media addict 00:09:31 – "Perceived social isolation" and why the brain can't tell the difference 00:10:21 – Meta-analysis of 3.4 million people 00:10:55 – Loneliness vs obesity and smoking risk comparisons 00:11:18 – The biology of loneliness begins 00:11:50 – NF-kB: inflammatory gene activation explained 00:12:33 – How loneliness changes gene expression 00:13:02 – Chronic inflammation and disease pathways 00:13:21 – Cortisol, sleep disruption, and immune dysfunction 00:14:00 – How loneliness affects brain repair and amyloid plaque clearing 00:14:21 – Sponsor: Fatty15 and cellular health 00:18:02 – The Alzheimer's and dementia connection 00:18:25 – Loneliness as a major modifiable dementia risk factor 00:18:57 – Cortisol, neuroinflammation, and brain degeneration 00:19:16 – The hippocampus physically shrinking in lonely people 00:19:27 – Social media as a "fatal convenience" 00:19:57 – The oxytocin economy: connection as medicine 00:20:15 – Oxytocin as one of the body's strongest anti-inflammatory molecules 00:20:30 – HeartMath research: emotional synchronization between people 00:20:48 – "You regulate each other's biology" 00:21:07 – The real barrier: vulnerability 00:21:32 – Darin's recent experiences with radical vulnerability 00:21:54 – Conversations with family, ex-partners, and loved ones 00:22:35 – Brené Brown's research on connection and worthiness 00:23:14 – The "depth audit" exercise 00:23:42 – Reaching out, expressing appreciation, and owning your emotions 00:24:01 – Sacred hours: spending time without phones 00:24:13 – Questions that create real intimacy 00:24:30 – Darin's emotional conversation with his brother 00:25:03 – Protecting yourself from social media disconnection 00:25:20 – Becoming a source of joy and connection in everyday life 00:25:25 – Darin reflects on seven years of subtle loneliness 00:25:48 – The shift from surface conversations to meaningful connection 00:26:01 – "If you want love, give love" 00:26:19 – Final message: generate the connection you want to receive 00:26:22 – Closing thoughts and outro Thank You to Our Sponsors Truniagen: Go to www.truniagen.com and use code DARIN20 at checkout for 20% off Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness Key Takeaway "Loneliness isn't weakness. It isn't failure. It's a biological signal telling you that something essential is missing. And in a world addicted to surface-level connection, the real medicine may simply be this: vulnerability, presence, eye contact, honesty, and the courage to let yourself truly be seen." Bibliography/Sources The Loneliness Epidemic & Public Health Data Bureau of Labor Statistics. (2023). American time use survey. U.S. Department of Labor. https://www.bls.gov/tus/ Cigna. (2023). Cigna U.S. loneliness index. Evernorth Health Services. https://newsroom.cigna.com/loneliness-epidemic-continues-to-rise-cigna-study Murthy, V. H. (2023). Our epidemic of loneliness and isolation: The U.S. Surgeon General's advisory on the healing effects of social connection and community. U.S. Department of Health and Human Services. https://www.hhs.gov/sites/default/files/surgeon-general-social-connection-advisory.pdf Survey Center on American Life. (2021). The state of American friendship: Change, challenges, and loss. American Enterprise Institute. https://www.americansurveycenter.org/research/the-state-of-american-friendship-change-challenges-and-loss/ Mortality & Systemic Health Risk Cohen, S., Doyle, W. J., Skoner, D. P., Rabin, B. S., & Gwaltney, J. M. (1997). Social ties and susceptibility to the common cold. JAMA, 277(24), 1940–1944. https://pubmed.ncbi.nlm.nih.gov/9200634/ Hawkley, L. C., & Cacioppo, J. T. (2010). Loneliness matters: A theoretical and empirical review of consequences and mechanisms. Annals of Behavioral Medicine, 40(2), 218–227. https://pubmed.ncbi.nlm.nih.gov/20396846/ Holt-Lunstad, J., Smith, T. B., Baker, M., Harris, T., & Stephenson, D. (2015). Loneliness and social isolation as risk factors for mortality: A meta-analytic review. Perspectives on Psychological Science, 10(2), 227–237. https://doi.org/10.1177/1745691614568352 Valtorta, N. K., Kanaan, M., Gilbody, S., Ronzi, S., & Hanratty, B. (2016). Loneliness and social isolation as risk factors for coronary heart disease and stroke. Heart, 102(13), 1009–1016. https://heart.bmj.com/content/102/13/1009 Genetics, Inflammation & The Immune System Cole, S. W. (2013). Social regulation of human gene expression: Mechanisms and implications for public health. American Journal of Public Health, 103(S1), S84–S92. https://pmc.ncbi.nlm.nih.gov/articles/PMC3786756/ Cole, S. W., Hawkley, L. C., Arevalo, J. M. G., Sung, C. Y., Rose, R. M., & Cacioppo, J. T. (2007). Social regulation of gene expression in human leukocytes. Genome Biology, 8(9), Article R189. https://pmc.ncbi.nlm.nih.gov/articles/PMC2375027/ Sleep & Cognitive Decline Cacioppo, J. T., Hawkley, L. C., Berntson, G. G., Ernst, J. M., Gibbs, A. C., Stickgold, R., & Hobson, J. A. (2002). Do lonely days invade the nights? Potential social modulation of sleep efficiency. Psychological Science, 13(4), 384–387. https://pubmed.ncbi.nlm.nih.gov/12137144/ Holwerda, T. J., Deeg, D. J. H., Beekman, A. T. F., et al. (2014). Feelings of loneliness, but not social isolation, predict dementia onset. Journal of Neurology, Neurosurgery & Psychiatry, 85(2), 135–142. https://jnnp.bmj.com/content/85/2/135 Oxytocin & The Biology of Connection Szeto, A., Sun-Suslow, N., Mendez, A. J., Hernandez, R. I., Wagner, K. V., & McCabe, P. M. (2017). Regulation of the macrophage oxytocin receptor in response to inflammation. American Journal of Physiology—Endocrinology and Metabolism, 312(2), E183–E189. https://journals.physiology.org/doi/full/10.1152/ajpendo.00424.2016 Uvnas-Moberg, K. (2003). The oxytocin factor: Tapping the hormone of calm, love, and healing. Da Capo Press. https://books.google.com/books?id=b-aKjQoB_nQC Psychology, Vulnerability & Relationship Science Aron, A., Melinat, E., Aron, E. N., Vallone, R. D., & Bator, R. J. (1997). The experimental generation of interpersonal closeness. Personality and Social Psychology Bulletin, 23(4), 363–377. https://doi.org/10.1177/0146167297234003 Brown, B. (2010). The gifts of imperfection: Let go of who you think you're supposed to be and embrace who you are. Hazelden Publishing. https://brenebrown.com/book/the-gifts-of-imperfection/ Cacioppo, J. T., & Patrick, W. (2008). Loneliness: Human nature and the need for social connection. W. W. Norton & Company. https://wwnorton.com/books/9780393335286 Dunbar, R. I. M. (2012). Bridging evolutionary approaches to the social brain and social bonding. In F. B. M. de Waal & P. F. Ferrari (Eds.), The primate mind. Harvard University Press. https://www.hup.harvard.edu/books/9780674063104 Dunbar, R. I. M. (2021). Friends: Understanding the power of our most important relationships. Little, Brown and Company. https://www.hachettebookgroup.com/titles/robin-dunbar/friends/9781408711736/ Waldinger, R., & Schulz, M. (2023). The good life: Lessons from the world's longest scientific study on happiness. Simon & Schuster. https://www.simonandschuster.com/books/The-Good-Life/Robert-Waldinger/9781982166694

13. Nuclear Non-Proliferation and the Iranian Dispute Guest: Henry Sokolski Henry Sokolski discusses the NPTreview conference, debating whether an "inalienable right" to enrich uranium exists and the lack of enforcement mechanisms to prevent countries from manufacturing nuclear weapons. 131900 BROADWAY EVENING POSTCARD