Podcasts about cardiovascular

This year is the 50th anniversary of the first transcatheter ASD closure in a human. To celebrate this achievement, this week we air a live interview from PICS 2025 in Chicago (conducted 8/26/25) with living interventional cardiology legend Dr. Terry King speaking about the events surrounding his landmark intervention as the first person to ever perform a transcatheter ASD closure with his partner, surgeon Dr. Noel Mills. In this one on one interview, Dr. King discusses how he came up with this idea with Dr. Mills and how he found a patient in which to proceed. He reviews what 'informed consent' was in 1975 and also how he and Dr. Mills accurately estimated ASD size in an era that preceded 2D echocardiography. Dr. King speaks about the role of family in his life and offers advice to the next generation. Finally, he shares with us what he is up to today and why he does not believe in retirement. Prepare to be excited and inspired by this wonderful figure in our field. 

What does it really take to bring cutting-edge vascular care to the most underserved corners of the rural South? In this episode of the BackTable Podcast, host Dr. Ally Baheti welcomes interventional cardiologist Dr. Ash Sastry and interventional radiologist Dr. Sree Nair to discuss the financial and regulatory side of providing care to underserved rural populations in North Carolina, Virginia, and Georgia.---SYNPOSISThe doctors delve into the operations and challenges of running an office-based lab (OBL) and the potential transition to an ambulatory surgical center (ASC). This episode covers topics like certificate of need (CON) laws, reimbursement issues, and the importance of multidisciplinary collaboration. The conversation offers insights into the practical and regulatory hurdles faced in delivering high-quality vascular care in rural settings. ---TIMESTAMPS00:00 - Introduction02:14 - Challenges in Rural Healthcare09:00 - Understanding Certificate of Need (CON) Laws11:30 - The Financial Struggles of OBLs19:58 - Advocacy and Legislative Efforts27:53 - Future Prospects and Final Thoughts

In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Professor Vijay Kunadian from the University of Newcastle and Sarah Brown, a patient with heart disease, who are both co-authors on a consensus statement. They discuss the state of research participation among females in each area of cardiovascular disease, identify barriers to research for females in each area, and finally, describe strategies to increase female involvement in cardiovascular research. If you enjoy the show, please leave us a positive review wherever you get your podcasts. It helps us reach more people - thank you! Link to published paper: Paper - https://heart.bmj.com/content/early/2025/05/28/heartjnl-2024-325545 Editorial - https://heart.bmj.com/content/early/2025/05/28/heartjnl-2025-325979

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Angela is joined by Dr. Uma Naidoo, a renowned psychiatrist and nutrition expert, who discusses the intricate relationship between nutrition, mental health, and brain function, particularly during pivotal life stages such as perimenopause and postpartum, and advocates for a diet rich in fibre, antioxidants, and anti-inflammatory ingredients. KEY TAKEAWAYS: Impact of Added Sugars: High consumption of added sugars, especially from ultra-processed foods, can negatively affect mood and brain health Diet and Brain Health: To protect brain health, particularly during hormonal changes such as perimenopause and menopause, it's crucial to focus on a diet rich in fibre, antioxidants, and anti-inflammatory foods Cardiovascular and Brain Connection: There is a significant link between cardiovascular health and brain health. A healthy diet and lifestyle can improve both heart and brain function Stress Management: Chronic stress can have detrimental effects on the brain, leading to issues like anxiety and poor eating habits TIMESTAMPS AND KEY TOPICS: [00:10:36] Nutrition and cognitive health. [00:14:06] Effects of stress on the brain. [00:19:06] Menopause brain health. [00:28:58] Medication and motherhood challenges. [00:34:39] Importance of sleep hygiene. [00:38:29] Anxiety and food connection. VALUABLE RESOURCES Join The High Performance Health Community Click here for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible: LVLUP HEALTH: Slow aging, repair gut health boost collagen and recovery and more with LVLUP Health's amazing products. Save 15% with code ANGELA at https://lvluphealth.com/angela The future of women's health is here - click to join my longevity community for women - Live Younger - at the special Founding Member Rate ABOUT THE GUEST Dr. Uma Naidoo is a Harvard trained nutritional psychiatrist, professional chef, and nutritionalbiologist & author of the national & international bestseller: “This is Your Brain on Food.” Hermost recent best-selling book is “Calm Your Mind with Food.”The late Michelin-starred chef David Bouley described Dr. Uma Naidoo as the world's first“triple threat” in the food and medicine space as the nexus of her interests have found their niche in Nutritional Psychiatry. Her first book has already been published in 23 countries and 19 languages. https://umanaidoomd.com/ https://www.instagram.com/drumanaidoo/ ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. CONTACT DETAILS Instagram Facebook LinkedIn Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast. This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/

Understanding the physical processes the body uses to compensate for the lack of gravity is important for maintaining astronaut health.

Join Dr. Kevin Shah as he delves into the alarming rise of heart disease within the South Asian population. In this eye-opening podcast, Dr. Shah explores the genetic predispositions, lifestyle choices, and dietary habits that contribute to this pressing issue. Discover the preventive measures and tailored healthcare approaches that can make a difference in managing heart disease in this community. Tune in for expert insights, real-life stories, and actionable advice that could save lives.  Learn more about Kevin Shah, M.D. 

In this "Meet the Experts" HeartTalk, host Melanie Lawson, MS, speaks with Ana Mercurio-Pinto, vice president of Care Transformation Services at MedAxiom. With a rich background in academic medicine, cardiovascular service line operations, and research management, Ana shares how her work is reshaping the future of care delivery. From optimizing physician performance and budgets to integrating complex hospital-physician systems, Ana brings a forward-thinking approach to transforming cardiovascular organizations. She also shares pivotal moments in her personal life that have fueled her commitment to innovation and collaboration.Guest Bio:Ana A. Mercurio-PintoVice President, Care Transformation ServicesAs Vice President of Care Transformation Services at MedAxiom, Ana applies her wide range of experience in budgeting, forecasting, physician/practice profit and loss reports, clinical and federal/non-federal research operations, new program development, service-line integration, and dyad and other matrixed leadership structures to help cardiovascular organizations transform care. Energized by the possibilities, Ana has a keen interest in helping members better integrate hospital/physician organization, ease faculty transitions, optimize staffing, improve administrative and research operations, and launch startup ventures.She has extensive professional experience running large, multi-specialized cardiovascular medicine divisions and has had the privilege of working and partnering with some of the industry's thought leaders, including master clinicians, practice-changing clinical trial investigators, and groundbreaking research scientists. She is dedicated to developing nimble and adaptive organizations that combine the best of traditional practice with the spirit of continuous modernization in the face of evolving and changing times.Ana has a bachelor's degree in business administration from Boston University Questrom School of Management and a master's in management with a concentration in healthcare management. Additionally, Ana has pursued certificates in launching new ventures and research administration.

In this episode of the Medical Sales Podcast, Samuel Adeyinka sits down with Gina Torres, a nurse-turned-medical device sales professional at Johnson & Johnson, to unpack what it really takes to thrive in one of the most competitive fields in healthcare: peripheral vascular and coronary sales. Gina shares her inspiring journey from working multiple nursing jobs to consolidating her career into one life-changing role in medical device sales. She reveals how she broke into the industry, why she chose Shockwave's groundbreaking intravascular lithotripsy technology, and what makes the clinical specialist role such a powerful entry point for both clinicians and driven non-clinicians. From balancing 5 a.m. case starts to late-night procedures, Gina gives a behind-the-scenes look at the unpredictable but rewarding life of a vascular rep. She also breaks down the income potential, the skills that truly separate top performers, and why grit, empathy, and the ability to “get comfortable being uncomfortable” matter more than a clinical background. Whether you're a nurse considering the leap, a bachelor's graduate wondering if you can compete, or an aspiring sales rep curious about cardiovascular devices, this conversation delivers raw insights, career strategies, and real talk about success in medical sales. Connect with Gina: LinkedIn Connect with Me: LinkedIn Love the show? Subscribe, rate, review, and share! Here's How » Want to connect with past guests and access exclusive Q&As? Join our EYS Skool Community today!

In this episode of Better Edge, C. Charles Jain, MD, the new associate medical director for Adult Congenital Heart Disease at Northwestern Medicine Bluhm Cardiovascular Institute, shares his clinical expertise and strategic vision for advancing adult congenital heart disease (ACHD) care. Dr. Jain discusses his new role and outlines a comprehensive approach to improving outcomes for ACHD. He emphasizes the importance of multidisciplinary collaboration and seamless transitions from pediatric to adult care, key parts of Northwestern Medicine's approach. Dr. Jain also highlights his research interests, commitment to providing whole-person care and upcoming initiatives to expand access and enhance continuity of care at Bluhm Cardiovascular Institute.

I am delighted to have the privilege of reconnecting with Dr. Deb Matthew today. She joined me once before in Episode 259. She is a distinguished best-selling author, international speaker, and dedicated educator known as the Happy Hormone Doctor.  Cardiovascular disease is the number one killer of women in the United States, causing one of every 3.2 deaths among women annually. In our conversation today, Dr. Matthew and I delve into the realm of cardiovascular disease, exploring the benefits of hormone replacement therapy, essential laboratory testing, medications, and the neurocognitive changes that occur during perimenopause and menopause. We also focus on lifestyle, gut testing, and the all-time favorite topic of weight loss resistance.  Stay tuned for today's engaging, enriching, and enlightening discussion with Dr. Deb Matthew. IN THIS EPISODE YOU WILL LEARN: How HRT reduces the risk of cardiovascular disease  How long-term use of estrogen can reduce the risk of heart disease over time Why should you do a hormone panel before starting HRT? How cortisol levels impact cardiovascular health How the coronary calcium score helps to predict heart attack risk Cholesterol markers and their significance in cardiovascular risk assessment Managing cholesterol levels in perimenopausal women The importance of addressing underlying hormonal imbalances in women to mitigate cognitive decline and lipid disorders The connection between gut health and brain fog How women's testosterone levels impact their cognition and motivation Hormone imbalance and weight loss resistance in women  Connect with Cynthia Thurlow Follow on ⁠Twitter⁠ ⁠Instagram⁠ ⁠LinkedIn⁠ Check out Cynthia's ⁠website⁠. Submit your questions to ⁠support@cynthiathurlow.com⁠. Connect with Dr. Deb Matthew On her ⁠website⁠ ⁠Facebook⁠ ⁠Instagram⁠ Dr. Deb Mathew's book ⁠This is Not Normal on Amazon⁠ or ⁠download the ebook⁠  Previous Episode featuring Dr. Matthew ⁠Ep. 295: HRT's Impact on Women's Health Through Time with Dr. Deb Matthew

Send us a textDr. Michael Koren joins Kevin Geddings to explain how having a conversation with a medical professional who is tuned into your personal situation can help you understand the confusing and sometimes counterintuitive world of medical information. Cardiologist Dr. Koren uses the examples of coronary calcium scores and total cholesterol levels, which must be interpreted in the context of individual factors, such as age and HDL/LDL ratio. They then discuss clinical research and how the experience in a clinical research setting is one of shared knowledge, where medical professionals take the time to explain everything you need to know about your health.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!

Liver, Lipids, and the Left Ventricle

In today's episode of Barbell Shrugged, Anders Varner, Doug Larson, and Travis sit down with Anders coach, Dr. Mike T. Nelson. For those that have followed the show, you know Anders has been in pursuit of running a sub-6 minute mile at the age of 40. Dr. Nelson is the coach Anders hired to help with that goal. In this episode the crew walks through program design, initial intake, and execution of how to build cardiovascular fitness. You will learn performance tests used to design Anders training program, how priorities are scheduled into a busy life, understanding higher intensity efforts mixed with Vo2Max training, Zone 2 efforts, and how to maintain strength throughout the process. We hope you enjoy. Visit https://rapidhealthoptimization.com Work with Dr. Nelson Anders Varner on Instagram Doug Larson on Instagram Coach Travis Mash on Instagram

In this week's replay episode from 3 years ago, we delve into the world of pediatric heart transplantation and the impact that race or insurance status may have on outcomes. What are the factors that explain worse outcomes for black children waiting for a heart transplant? How is the PHTS Racial Disparity Taskforce working to reduce inequities in this field? What role does insurance status have on these outcomes? We speak with noted heart failure and transplantation expert, Dr. Neha Bansal who is Associate Professor of Pediatrics at The Icahn School of Medicine at Mount Sinai about this recent PHTS multicenter study.DOI: 10.1016/j.healun.2022.12.002

About the Guest(s): Dr. Kristin Hieshetter is a dedicated specialist in functional health and a passionate podcast host of Functional Health Radio. Known for her focus on holistic health and wellness, Dr. Hieshetter is deeply invested in raising awareness about the potential dangers lurking in everyday products, especially those purported to be healthy alternatives. Her insightful discussions aim to educate listeners, encouraging them to make healthier choices and reduce toxins in their lives. Dr. Hieshetter's expertise is informed by years of practice and collaboration with other healthcare professionals. Episode Summary: Join Dr. Kristin Hieshetter in this intriguing episode of Functional Health Radio as she delves into the world of artificial sweeteners, specifically erythritol. This episode is interwoven with gratitude and the importance of making informed health decisions. Dr. Hieshetter explores erythritol's potential health risks and provides listeners with essential information to navigate the complex landscape of sweeteners. This discussion is particularly critical for those with predispositions to cardiovascular diseases. In this episode, Dr. Hieshetter discusses erythritol's implications on health, backed by recent studies such as the one from Nature and Medicine in March 2023. She explains how erythritol can enhance the risk of major cardiovascular events, highlighting a 150% increase in overall mortality risk linked to the artificial sweetener, with pronounced concerns for heart attack, stroke, and cancer. Dr. Hieshetter underscores the importance of identifying and avoiding erythritol in various products to maintain optimal health. Key Takeaways: Erythritol and Cardiovascular Risks: Recent studies indicate a strong association between erythritol intake and increased risks of heart attack and stroke, primarily due to its impact on blood clots and platelet activity. Mortality and Long-Term Health Impact: A 150% increased overall mortality risk is associated with erythritol consumption, with significant implications for cardiovascular diseases and stroke. Natural vs. Artificial Erythritol: While erythritol occurs naturally in certain fruits and foods, the concentrated form used as an artificial sweetener poses substantial health risks. Consumer Awareness is Key: Erythritol often lurks in sugar-free and keto-friendly foods; understanding this can help individuals avoid unintended health risks. Practical Tips for Healthier Choices: Check product labels and stay informed about the ingredients in seemingly "healthy" food options, particularly those targeting specific diets like keto and paleo. Notable Quotes: "I'm especially thankful for all the listeners; I hope that you guys are getting healthier each week." "Erythritol is no joke…it enhances platelet activity and thrombosis." "The risk of myocardial infarct and stroke is huge with erythritol." "You double your risk of stroke if you are using erythritol." "When erythritol occurs naturally in fruits and fermented foods, is it as deadly? No." Resources: Recent Studies: Nature and Medicine: "The Artificial Sweetener Erythritol and Cardiovascular Event Risk," March 2023. Nutrients Journal: "Serum Erythritol and Risk of Overall and Cause Specific Mortality in a Cohort of Men," September 2024. Listeners are encouraged to explore these topics further for a deeper understanding of the impact erythritol may have on health. Tune in to the full episode for a comprehensive discussion and keep listening to Functional Health Radio for more insights on living a toxin-free, healthier life. Stay tuned for more enlightening content!

O que o estudo mais recente sobre anabolizantes e risco cardiovascular mostrou? by Cardiopapers

Full shownotes, transcript and resources here: https://soundbitesrd.com/292                The Forgotten Vitamin: K2's Role in Cardiovascular and Skeletal Health Vitamin K2 might not be the first nutrient you think of when it comes to heart health or bone health – but it should definitely be on your list of important nutrients. This episode explores the science behind vitamin K2, how it differs from K1, and its role alongside other nutrients in supporting cardiovascular and skeletal health. Tune in to this episode to learn about: ●       the differences between vitamin K1 and K2 ●       why K2 matters for heart and bone health ●       food sources and if they are common in the diet ●       how much vitamin K2 is recommended ●       other nutrients that work with vitamin K2 to support heart and bone health ●       research on vitamin K2's role in heart and bone health including the AVADEC Trial ●       what to look for in supplements ●       ways to assess the quality of supplements ●       updated vitamin D recommendations ●       preventing deficiency vs. optimal amounts of nutrients ●       resources for health professionals and the public

Cardiovascular disease is the No. 1 killer in the United States. It's also often referred to as the “silent killer” because many of the factors that contribute to it happen internally overtime, without noticeable symptoms. Tuning in to and understanding your cardiovascular health requires a holistic lens that goes beyond knowing your cholesterol levels. In this episode, Jim LaValle, RPh, CCN, shares the hidden causes of heart disease, how it progresses, and how to prevent and potentially reverse it, so you can own your cardiovascular health and be “heart smart.”   This episode of Life Time Talks is part of our series on Performance and Longevity with MIORA.   Find the episode highlights, get related resources and view the transcript for this episode at https://experiencelife.lifetime.life/podcast/becoming-heart-smart-performance-longevity-series   Have thoughts you'd like to share or topic ideas for future episodes? Email us at lttalks@lt.life — we'd love to hear from you!   Follow us on Instagram: @lifetime.life   The information in this podcast is intended to provide broad understanding and knowledge of healthcare topics. This information is for educational purposes only and should not be considered complete and should not be used in place of advice from your physician or healthcare provider. We recommend you consult your physician or healthcare professional before beginning or altering your personal exercise, diet or supplementation program. 

Today I'm joined by Dr. Latt Mansor, a leading voice in human metabolism and performance. With a PhD from Oxford and years of research on type 2 diabetes, cardiovascular health, and performance in extreme environments, Latt has a unique perspective on how our bodies work and how to help them thrive. We get into the fundamentals of metabolic health, the latest research on ketones, and how his studies with the Department of Defense are shaping the future of performance science. He breaks down what everyday health optimization really looks like, from fueling strategies to improving insulin sensitivity, and explains why metabolism exists on a spectrum.→ Leave Us A Voice Message!Topics Discussed:→ What is metabolic health and how can you improve it?→ How do ketones support energy and performance?→ What are the signs of insulin resistance?→ Can ketones help with inflammation and recovery?→ How do you fuel for muscle gain and fat loss?Sponsored By: → Ketone-IQ | Go to https://hvmn.com/KELLY and use discount code "BEWELL" for 30% off your subscription order + a free gift with a second order.→ Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at bewellbykelly.com.→ WeNatal | You can use my link, wenatal.com/kelly, with any subscription order, to get a free one month supply of WeNatal's Omega DHA+ Fish Oil valued at 35→ Vuori | Get 20% off your first order of Vuori AND free shipping on orders over $75 at vuori.com/kellyTimestamps: → 00:00:00 - Introduction → 00:01:21 - Dr. Latt's background → 00:05:40 - Improving your metabolism → 00:10:14 - Ketones & fat → 00:14:54 - Cardiovascular health → 00:17:51 - Energy deficiency → 00:20:07 - Checking for insulin resistance → 00:23:31 - Consistent lifestyle change → 00:27:23 - Carbs & ketones → 00:32:34 - Fueling for body recomposition → 00:36:21 - Muscle vs fat & the scale → 00:39:19 - Muscle gains → 00:46:36 - Ketone-IQ Dosing → 00:52:19 - Infant neurodevelopment → 00:55:36 - Ketones & inflammation → 00:57:44 - Metabolism is a spectrum → 00:59:05 - What's next for Ketone-IQ? Further Listening: → The Truth About Ketones: Benefits, Use Cases & Impact on Brain Health | Dr. Latt MansorStudies: → Exploring the role of ketone bodies in the diagnosis and treatment of psychiatric disorders→ ResearchCheck Out Dr. Latt: → Instagram: @lattmansor→ Website→

Show Notes Ethel Frese, PT, DPT, MHS, CCS, FAPTA is one of the most respected voices in acute and cardiopulmonary physical therapy. In this episode, she shares the pearls that will energize your practice and growth—from building stronger patient connections to fostering collaboration with the healthcare team. Whether you're new to acute care or a seasoned clinician, her insights will challenge, inspire, and remind you why this work matters. Today's Guests: Ethel Frese, PT, DPT, MHS, CCS, FAPTA Professor Emeritus Saint Louis University, Cardiovascular and Pulmonary Certified Clinical Specialist ethel.frese@health.slu.edu Guest Quotes: 17:46 “ the therapist who took my place in Chattanooga… she's always told students and people that I've worked with that one of the best gifts to me as a teacher is to have someone you've taught do better than the teacher.  And I have a lot of really good gifts that way. Lots of people I've seen have gone way beyond their teacher and, and that's huge to me.” 28:54 “ I think that's a value of teaching.  You have to go back and think, now, why do I do it that way?” Rapid Responses:  Name one therapist that has been influential in your career. “Oh, that's an easy one. Her name is Mary Chrisman.  She was the therapist that I went to at the hospital when the other therapist would not answer my questions. And she's a friend even to today… You know you work in acute care when…   “When you can manage. I'm gonna say acute illness, but you know, ill patients who need specialist, very specialized care.    And that you can manage the, the really sick patients and the not so sick. Yeah. And you know, you're good at vital signs and ECG and ventilators and all the machinery that you see in acute care. Yeah. So, I guess that's my answer.”

What if you could measure how fast your immune system is ageing—and actually reverse it? In this groundbreaking episode, I sit down with Nikolina Lauc, CEO and co-founder of GlycanAge, to unpack the science behind one of the most accurate biological age tests available today. We explore how lifestyle, hormones, and stress directly impact your biological age—and how you can use cutting-edge science to turn back the clock. KEY TAKEAWAYS: Glycans as Aging Markers: Glycans reflect the state of your immune system and offer early warning signs for chronic disease Men vs Women's Aging Patterns: Women experience a rapid biological ageing spike during perimenopause and menopause Impact of Stress on Aging: Chronic psychological stress can accelerate biological ageing by up to 15 years Hormone Therapy Benefits: Starting oestrogen therapy around menopause can lower biological age by up to 10 years  TIMESTAMPS AND KEY TOPICS: [00:06:28] Aging immune system and inflammation. [00:08:12] Glycans as aging measurement. [00:26:40] Cost of sports on women. [00:35:07] Stress impacts biological age. [00:45:35] Cardiovascular health awareness. [00:50:50] NAD precursors and glyconate. [00:56:21] Aging research and health empowerment. VALUABLE RESOURCES Click here for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible: Check out Defender Shield's products and save 10% with code ANGELA at Defendershield.com/angela To get a 15 day free trial of the Quantum Upgrade, go to https://quantumupgrade.io/and use code ANGELA15 Test your biological age and gain powerful insights into your longevity and health Glycanage use code ANGELA15 for your exclusive listener discount  ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. CONTACT DETAILS Instagram Facebook LinkedIn Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast.

About this Episode Episode 48 of “The 2 View” – Burn Tx, Marijuana & CV Risk, Ocular Syphilis, and HSV 1 & 2 Segment 1 – Thermal Burn Treatment Levin NJ, Erben Y, Li Y, et al. Edited by Muacevic A, Adler JR. A Systematic Review and Meta-Analysis Comparing Burn Healing Outcomes Between Silver Sulfadiazine and Aloe vera. Cureus. 2022;14(10):e30815. Accessed August 11, 2025. https://pmc.ncbi.nlm.nih.gov/articles/PMC9621733/ Aziz Z, Abdul Rasool Hassan B. The effects of honey compared to silver sulfadiazine for the treatment of burns: A systematic review of randomized controlled trials. Burns. 2017;43(1):50-57. Accessed August 11, 2025. https://pubmed.ncbi.nlm.nih.gov/27576926/ Segment 2A – Marijuana and Cardiovascular Risk Mohammadi L, Navabzadeh M, Jimenez-Tellez N, et al. Association of Endothelial Dysfunction With Chronic Marijuana Smoking and THC-Edible Use. JAMA Cardiol. Published online May 28, 2025. doi:10.1001/jamacardio.2025.1399. Accessed August 11, 2025. https://jamanetwork.com/journals/jamacardiology/fullarticle/2834540 Storck W, Elbaz M, Vindis C, et al. Eifling KP, Gaudio FG, Dumke C, et al. Cardiovascular risk associated with the use of cannabis and cannabinoids: a systematic review and meta-analysis. Heart. Published online June 17, 2025. doi:10.1136/heartjnl-2024-325429. Accessed August 11, 2025. https://pubmed.ncbi.nlm.nih.gov/40527600/ Page II RL, Allen LA, Kloner RA, et al. Medical Marijuana, Recreational Cannabis, and Cardiovascular Health: A Scientific Statement From the American Heart Association. Circulation. 2020;142(10);e131-152. https://www.ahajournals.org/doi/full/10.1161/CIR.0000000000000883 Segment 2B – Ocular Syphilis Zhou LR, Kirupaharan N, Birkenstock MK. Incidence and Prevalence of Syphilitic Uveitis and Associated Ocular Complications in the TriNetX Database. Am J Ophthalmol. 2025;277:387-394. https://www.sciencedirect.com/science/article/pii/S0002939425002843 Segment 3 - HSV 1 & 2 Langenberg AGM, Corey L, Ashley RL, et al. A Prospective Study of New Infections with Herpes Simplex Virus Type 1 and Type 2. N Engl J Med. 1999;341:1432-1438. https://www.nejm.org/doi/full/10.1056/nejm199911043411904 Lebrun-Vignes B, Bouzamondo A, Dupuy A, et al. A meta-analysis to assess the efficacy of oral antiviral treatment to prevent genital herpes outbreaks. J Am Acad Dermatol. 2007;57(20):238-246. Recurring Sources Center for Medical Education. http://ccme.org The Proceduralist. http://www.theproceduralist.org The Procedural Pause. https://journals.lww.com/em-news/blog/theproceduralpause/pages/default.aspx The Skeptics Guide to Emergency Medicine. http://www.thesgem.com Be sure to keep tuning in for more great prizes and fun trivia questions! Once you hear the question, please email us your guesses at 2viewcast@gmail.com and tell us who you want to give a shout-out to.

This week we lost one of the true 'nice people' in pediatric cardiology - Dr. Richard J. Golinko who died at the age of 95. Dr. Golinko led the Mount Sinai Pediatric Cardiology Program for many years. He established many of the programs at Sinai that are now fundamental to the program and the care of children with congenital heart disease in the tri-state region. To honor Dr. Golinko's memory, we stretch back over 40 years to review a paper he co-wrote with Dr. Rubin Cooper on balloon angioplasty of aortic coarctation. We speak with Dr. Cooper, the work's first author about the work as well as his remembrances of the man, Dr. Golinko. Also joining us this week is Dr. Anthony Rossi of Nicklaus Children's Hospital and Dr. Rica Arnon of Mount Sinai to share their individual remembrances of this wonderful and warm leader. doi: 10.1161/01.cir.70.5.903

Jaume Segalés y los responables de Mundo Natural hablan de salud y de la salud cardiovascular.

In the July 2025 episode of Critical Decisions in Emergency Medicine, Drs. Danya Khoujah and Wendy Chang discuss cardiovascular disorders in the emergency department observation unit and ectopic pregnancy presentations. As always, you'll also hear about the hot topics covered in the regular features, including chest pain in a health young adult in The Critical ECG, periosteal reaction in a newborn in Clinical Pediatrics, lunate dislocation in Critical Cases in Orthopedics and Trauma, intrapleural anesthesia in The Critical Procedure, phenobarbital for alcohol withdrawal syndrome in The LLSA Literature Review, a patient with acute renal failure in The Critical Image, suzetrigine in The Drug Box, and metaldehyde toxicity in The Tox Box.

Podcast Summary This episode of the Pain Exam Podcast, hosted by Dr. David Rosenblum, discusses an interesting article about Ketorolac injections for musculoskeletal conditions. The podcast covers: Ketorolac is an NSAID that provides analgesic and anti-inflammatory effects through inhibition of prostaglandin synthesis Multiple studies comparing Ketorolac injections to corticosteroids and hyaluronic acid for various conditions Research shows Ketorolac injections are equally effective as corticosteroids for subacromial conditions, adhesive capsulitis, carpal-metacarpal joint issues, and hip/knee osteoarthritis Ketorolac may be a safer alternative to steroids for certain patients, though it has its own contraindications for those with renal, gastrointestinal, or cardiovascular disease Dr. Rosenblum considers the potential of using Ketorolac injections directly at pain sites rather than intramuscularly Upcoming Courses and Conferences Ultrasound courses in New York and Costa Rica (check unwrappedpain.org) Private ultrasound sessions available Dr. Rosenblum will be speaking at Pain Week about ultrasound in pain practice and PRP Presenting at a primary care conference in London Teaching ultrasound at ISPN LAPSES conference in Chile (Dr. Rosenblum won't attend this year) Ketorolac Injections: An Effective Alternative for Musculoskeletal Pain Management Musculoskeletal conditions such as bursitis, adhesive capsulitis, and osteoarthritis affect millions and often require injectable therapies to reduce pain and inflammation. Traditionally, corticosteroid injections have been the mainstay treatment. However, concerns over side effects like tendon rupture, cartilage damage, and systemic hyperglycemia have prompted exploration of alternatives. A recent narrative review by Kiel et al. (2024) highlights ketorolac—a parenteral nonsteroidal anti-inflammatory drug (NSAID)—as a promising substitute for corticosteroids in musculoskeletal injections. Warning: OFF Label use of Ketorolac discussed. Please consult your physician. See full article  for details. Subacromial Ketorolac Injections for Shoulder Pain Subacromial bursitis and impingement syndrome are common causes of shoulder pain and disability. Several randomized controlled trials have shown that subacromial ketorolac injections provide pain relief and functional improvement comparable to corticosteroids: Goyal et al. demonstrated significant reductions in pain scores after subacromial injection of 60 mg ketorolac versus 40 mg methylprednisolone, with no difference in outcomes between groups. Taheri et al. found similar short-term pain relief at 1 and 3 months with either ketorolac or corticosteroid subacromial injections. Kim et al. reported equivalent clinical improvement in rotator cuff syndrome patients receiving ketorolac or triamcinolone injections. Min et al. noted ketorolac led to better forward flexion and patient satisfaction at 4 weeks compared to corticosteroids. These studies support ketorolac as an effective agent for subacromial injection, offering an alternative for patients where corticosteroid use is limited. Intra-articular Ketorolac Injections for Adhesive Capsulitis and Osteoarthritis Adhesive capsulitis (frozen shoulder) and osteoarthritis of the hip, knee, and carpometacarpal joint are often treated with intra-articular corticosteroids. Ketorolac injections have shown comparable efficacy in these conditions: Akhtar et al. found intra-articular ketorolac significantly reduced shoulder pain at 4 weeks in adhesive capsulitis compared to hyaluronic acid. Ahn et al. reported similar pain relief between intra-articular ketorolac and corticosteroid injections in adhesive capsulitis, with ketorolac providing superior shoulder mobility at 3 and 6 months. Koh et al. showed that adding ketorolac to hyaluronic acid injections in carpometacarpal osteoarthritis resulted in faster onset of pain relief compared to hyaluronic acid alone. Park et al. observed equivalent functional improvements with intra-articular ketorolac or corticosteroids in hip osteoarthritis. Jurgensmeier et al. demonstrated similar symptom improvement at 1 and 3 months post-injection for ketorolac and triamcinolone in hip and knee osteoarthritis. Xu et al. and Bellamy et al. confirmed ketorolac's comparable pain relief and functional benefits to corticosteroids for knee osteoarthritis, with ketorolac being more cost-effective. Lee et al. noted quicker pain reduction with intra-articular ketorolac combined with hyaluronic acid versus hyaluronic acid alone in knee osteoarthritis. aSafety and Pharmacologic Considerations Ketorolac's anti-inflammatory action stems from cyclooxygenase inhibition, reducing prostaglandin synthesis. Its half-life is approximately 5.2–5.6 hours, and it is metabolized in the liver. Unlike corticosteroids, ketorolac avoids systemic hyperglycemia and cartilage damage risks. Animal and in vitro studies suggest ketorolac may protect cartilage by inhibiting inflammatory cytokines. While gastrointestinal, renal, and cardiovascular risks associated with NSAIDs remain considerations, localized intra-articular and subacromial ketorolac injections may limit systemic exposure and adverse effects. Mild, transient post-injection pain has been reported but resolves without intervention. Conclusion Ketorolac injections, administered intra-articularly or subacromially, are a safe, effective, and economical alternative to corticosteroids for managing common musculoskeletal conditions. Their comparable efficacy in reducing pain and improving function, combined with a more favorable side effect profile, makes ketorolac an appealing option for clinicians and patients alike. Further research is warranted to fully elucidate long-term safety and optimal dosing strategies. FAQS Ketorolac Injections for Musculoskeletal Conditions: Frequently Asked Questions Musculoskeletal pain from conditions like bursitis, adhesive capsulitis, and osteoarthritis often requires injectable treatments. Ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), is emerging as a promising alternative to corticosteroids. Below are common questions and answers based on a recent narrative review by Kiel et al. (2024). 1. What is ketorolac and how does it work? Ketorolac is a parenteral NSAID that reduces pain and inflammation by inhibiting cyclooxygenase enzymes, which decreases prostaglandin synthesis. It can be administered orally, intramuscularly, intravenously, or by injection directly into joints or around bursae. 2. How effective is ketorolac for musculoskeletal conditions? Studies show ketorolac injections provide significant pain relief and functional improvement comparable to corticosteroids in conditions like: Subacromial bursitis and shoulder impingement (subacromial injections) Adhesive capsulitis (frozen shoulder) (intra-articular injections) Osteoarthritis of the hip, knee, and thumb carpometacarpal joint (intra-articular injections) 3. What evidence supports subacromial ketorolac injections? Randomized controlled trials found: Goyal et al. and Taheri et al. reported similar pain reduction and functional outcomes between ketorolac and corticosteroids for subacromial injections. Kim et al. and Min et al. observed comparable or better patient satisfaction and shoulder mobility with ketorolac versus corticosteroids. 4. How does intra-articular ketorolac compare to corticosteroids for adhesive capsulitis? Akhtar et al. showed ketorolac reduced shoulder pain more than hyaluronic acid. Ahn et al. found ketorolac and corticosteroids equally effective for pain relief, with ketorolac providing better shoulder mobility at 3 and 6 months. 5. What about ketorolac for osteoarthritis? Ketorolac combined with hyaluronic acid provided faster pain relief than hyaluronic acid alone in thumb carpometacarpal joint osteoarthritis (Koh et al.). Intra-articular ketorolac had similar efficacy to corticosteroids in hip (Park et al., Jurgensmeier et al.) and knee osteoarthritis (Bellamy et al., Xu et al.). Ketorolac injections were more cost-effective compared to corticosteroids (Bellamy et al.). 6. Are ketorolac injections safe? Ketorolac's side effects are similar to other NSAIDs, mainly involving gastrointestinal, renal, and cardiovascular risks. However, localized intra-articular and subacromial injections may reduce systemic exposure. Animal studies suggest ketorolac does not harm cartilage and may protect against inflammatory damage. Mild, transient local pain post-injection is possible but usually resolves without treatment. 7. What are the limitations of ketorolac use? Ketorolac is not suitable for patients with: Renal impairment Gastrointestinal ulcers or bleeding risk Cardiovascular disease or hypertension NSAID hypersensitivity, especially in asthma or chronic urticaria patients Clinicians should assess individual risks before choosing ketorolac injections. 8. How does ketorolac's pharmacokinetics affect its use? Ketorolac has a plasma half-life of about 5.2 to 5.6 hours and is metabolized in the liver. Pharmacokinetics for subcutaneous or intra-articular administration are less defined but systemic absorption occurs. Its relatively short half-life supports repeated dosing if needed. 9. Why consider ketorolac over corticosteroids? Ketorolac avoids corticosteroid-associated risks such as tendon rupture, cartilage damage, and steroid-induced hyperglycemia. It is also more cost-effective, making it a favorable option for patients and healthcare systems. 10. What further research is needed? More large-scale, long-term studies are needed to fully understand ketorolac's intra-articular effects, optimal dosing, and safety profile compared to corticosteroids and other treatments. Summary: Ketorolac injections, whether intra-articular or subacromial, offer a safe, effective, and economical alternative to corticosteroids for managing various musculoskeletal conditions. This makes ketorolac an important option in pain management and inflammation control.     Reference: Kiel J, Applewhite AI, Bertasi TGO, Bertasi RAO, Seemann LL, Costa LMC, Helmi H, Pujalte GGA. Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review. Clinical Medicine & Research. 2024;22(1):19-27. DOI: https://doi.org/10.3121/cmr.2024.1847 Disclaimer: This Podcast, website and any content from NRAP Academy (PMRexam.com) otherwise known as Qbazaar.com, LLC is  for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. Professionals should conduct their own fact finding, research, and due diligence to come to their own conclusions for treating patients. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.    

Podcast Summary This episode of the Pain Exam Podcast, hosted by Dr. David Rosenblum, discusses an interesting article about Ketorolac injections for musculoskeletal conditions. The podcast covers: Ketorolac is an NSAID that provides analgesic and anti-inflammatory effects through inhibition of prostaglandin synthesis Multiple studies comparing Ketorolac injections to corticosteroids and hyaluronic acid for various conditions Research shows Ketorolac injections are equally effective as corticosteroids for subacromial conditions, adhesive capsulitis, carpal-metacarpal joint issues, and hip/knee osteoarthritis Ketorolac may be a safer alternative to steroids for certain patients, though it has its own contraindications for those with renal, gastrointestinal, or cardiovascular disease Dr. Rosenblum considers the potential of using Ketorolac injections directly at pain sites rather than intramuscularly Upcoming Courses and Conferences Ultrasound courses in New York and Costa Rica (check unwrappedpain.org) Private ultrasound sessions available Dr. Rosenblum will be speaking at Pain Week about ultrasound in pain practice and PRP Presenting at a primary care conference in London Teaching ultrasound at ISPN LAPS  conference in Chile (Dr. Rosenblum won't attend this year) Ketorolac Injections: An Effective Alternative for Musculoskeletal Pain Management Musculoskeletal conditions such as bursitis, adhesive capsulitis, and osteoarthritis affect millions and often require injectable therapies to reduce pain and inflammation. Traditionally, corticosteroid injections have been the mainstay treatment. However, concerns over side effects like tendon rupture, cartilage damage, and systemic hyperglycemia have prompted exploration of alternatives. A recent narrative review by Kiel et al. (2024) highlights ketorolac—a parenteral nonsteroidal anti-inflammatory drug (NSAID)—as a promising substitute for corticosteroids in musculoskeletal injections. Warning: OFF Label use of Ketorolac discussed. Please consult your physician. See full article  for details. Subacromial Ketorolac Injections for Shoulder Pain Subacromial bursitis and impingement syndrome are common causes of shoulder pain and disability. Several randomized controlled trials have shown that subacromial ketorolac injections provide pain relief and functional improvement comparable to corticosteroids: Goyal et al. demonstrated significant reductions in pain scores after subacromial injection of 60 mg ketorolac versus 40 mg methylprednisolone, with no difference in outcomes between groups. Taheri et al. found similar short-term pain relief at 1 and 3 months with either ketorolac or corticosteroid subacromial injections. Kim et al. reported equivalent clinical improvement in rotator cuff syndrome patients receiving ketorolac or triamcinolone injections. Min et al. noted ketorolac led to better forward flexion and patient satisfaction at 4 weeks compared to corticosteroids. These studies support ketorolac as an effective agent for subacromial injection, offering an alternative for patients where corticosteroid use is limited. Intra-articular Ketorolac Injections for Adhesive Capsulitis and Osteoarthritis Adhesive capsulitis (frozen shoulder) and osteoarthritis of the hip, knee, and carpometacarpal joint are often treated with intra-articular corticosteroids. Ketorolac injections have shown comparable efficacy in these conditions: Akhtar et al. found intra-articular ketorolac significantly reduced shoulder pain at 4 weeks in adhesive capsulitis compared to hyaluronic acid. Ahn et al. reported similar pain relief between intra-articular ketorolac and corticosteroid injections in adhesive capsulitis, with ketorolac providing superior shoulder mobility at 3 and 6 months. Koh et al. showed that adding ketorolac to hyaluronic acid injections in carpometacarpal osteoarthritis resulted in faster onset of pain relief compared to hyaluronic acid alone. Park et al. observed equivalent functional improvements with intra-articular ketorolac or corticosteroids in hip osteoarthritis. Jurgensmeier et al. demonstrated similar symptom improvement at 1 and 3 months post-injection for ketorolac and triamcinolone in hip and knee osteoarthritis. Xu et al. and Bellamy et al. confirmed ketorolac's comparable pain relief and functional benefits to corticosteroids for knee osteoarthritis, with ketorolac being more cost-effective. Lee et al. noted quicker pain reduction with intra-articular ketorolac combined with hyaluronic acid versus hyaluronic acid alone in knee osteoarthritis. aSafety and Pharmacologic Considerations Ketorolac's anti-inflammatory action stems from cyclooxygenase inhibition, reducing prostaglandin synthesis. Its half-life is approximately 5.2–5.6 hours, and it is metabolized in the liver. Unlike corticosteroids, ketorolac avoids systemic hyperglycemia and cartilage damage risks. Animal and in vitro studies suggest ketorolac may protect cartilage by inhibiting inflammatory cytokines. While gastrointestinal, renal, and cardiovascular risks associated with NSAIDs remain considerations, localized intra-articular and subacromial ketorolac injections may limit systemic exposure and adverse effects. Mild, transient post-injection pain has been reported but resolves without intervention. Conclusion Ketorolac injections, administered intra-articularly or subacromially, are a safe, effective, and economical alternative to corticosteroids for managing common musculoskeletal conditions. Their comparable efficacy in reducing pain and improving function, combined with a more favorable side effect profile, makes ketorolac an appealing option for clinicians and patients alike. Further research is warranted to fully elucidate long-term safety and optimal dosing strategies. FAQS Ketorolac Injections for Musculoskeletal Conditions: Frequently Asked Questions Musculoskeletal pain from conditions like bursitis, adhesive capsulitis, and osteoarthritis often requires injectable treatments. Ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), is emerging as a promising alternative to corticosteroids. Below are common questions and answers based on a recent narrative review by Kiel et al. (2024). 1. What is ketorolac and how does it work? Ketorolac is a parenteral NSAID that reduces pain and inflammation by inhibiting cyclooxygenase enzymes, which decreases prostaglandin synthesis. It can be administered orally, intramuscularly, intravenously, or by injection directly into joints or around bursae. 2. How effective is ketorolac for musculoskeletal conditions? Studies show ketorolac injections provide significant pain relief and functional improvement comparable to corticosteroids in conditions like: Subacromial bursitis and shoulder impingement (subacromial injections) Adhesive capsulitis (frozen shoulder) (intra-articular injections) Osteoarthritis of the hip, knee, and thumb carpometacarpal joint (intra-articular injections) 3. What evidence supports subacromial ketorolac injections? Randomized controlled trials found: Goyal et al. and Taheri et al. reported similar pain reduction and functional outcomes between ketorolac and corticosteroids for subacromial injections. Kim et al. and Min et al. observed comparable or better patient satisfaction and shoulder mobility with ketorolac versus corticosteroids. 4. How does intra-articular ketorolac compare to corticosteroids for adhesive capsulitis? Akhtar et al. showed ketorolac reduced shoulder pain more than hyaluronic acid. Ahn et al. found ketorolac and corticosteroids equally effective for pain relief, with ketorolac providing better shoulder mobility at 3 and 6 months. 5. What about ketorolac for osteoarthritis? Ketorolac combined with hyaluronic acid provided faster pain relief than hyaluronic acid alone in thumb carpometacarpal joint osteoarthritis (Koh et al.). Intra-articular ketorolac had similar efficacy to corticosteroids in hip (Park et al., Jurgensmeier et al.) and knee osteoarthritis (Bellamy et al., Xu et al.). Ketorolac injections were more cost-effective compared to corticosteroids (Bellamy et al.). 6. Are ketorolac injections safe? Ketorolac's side effects are similar to other NSAIDs, mainly involving gastrointestinal, renal, and cardiovascular risks. However, localized intra-articular and subacromial injections may reduce systemic exposure. Animal studies suggest ketorolac does not harm cartilage and may protect against inflammatory damage. Mild, transient local pain post-injection is possible but usually resolves without treatment. 7. What are the limitations of ketorolac use? Ketorolac is not suitable for patients with: Renal impairment Gastrointestinal ulcers or bleeding risk Cardiovascular disease or hypertension NSAID hypersensitivity, especially in asthma or chronic urticaria patients Clinicians should assess individual risks before choosing ketorolac injections. 8. How does ketorolac's pharmacokinetics affect its use? Ketorolac has a plasma half-life of about 5.2 to 5.6 hours and is metabolized in the liver. Pharmacokinetics for subcutaneous or intra-articular administration are less defined but systemic absorption occurs. Its relatively short half-life supports repeated dosing if needed. 9. Why consider ketorolac over corticosteroids? Ketorolac avoids corticosteroid-associated risks such as tendon rupture, cartilage damage, and steroid-induced hyperglycemia. It is also more cost-effective, making it a favorable option for patients and healthcare systems. 10. What further research is needed? More large-scale, long-term studies are needed to fully understand ketorolac's intra-articular effects, optimal dosing, and safety profile compared to corticosteroids and other treatments. Summary: Ketorolac injections, whether intra-articular or subacromial, offer a safe, effective, and economical alternative to corticosteroids for managing various musculoskeletal conditions. This makes ketorolac an important option in pain management and inflammation control.     Reference: Kiel J, Applewhite AI, Bertasi TGO, Bertasi RAO, Seemann LL, Costa LMC, Helmi H, Pujalte GGA. Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review. Clinical Medicine & Research. 2024;22(1):19-27. DOI: https://doi.org/10.3121/cmr.2024.1847 Disclaimer: This Podcast, website and any content from NRAP Academy (PMRexam.com) otherwise known as Qbazaar.com, LLC is  for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. Professionals should conduct their own fact finding, research, and due diligence to come to their own conclusions for treating patients. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.  

Podcast Summary This episode of the Pain Exam Podcast, hosted by Dr. David Rosenblum, discusses an interesting article about Ketorolac injections for musculoskeletal conditions. The podcast covers: Ketorolac is an NSAID that provides analgesic and anti-inflammatory effects through inhibition of prostaglandin synthesis Multiple studies comparing Ketorolac injections to corticosteroids and hyaluronic acid for various conditions Research shows Ketorolac injections are equally effective as corticosteroids for subacromial conditions, adhesive capsulitis, carpal-metacarpal joint issues, and hip/knee osteoarthritis Ketorolac may be a safer alternative to steroids for certain patients, though it has its own contraindications for those with renal, gastrointestinal, or cardiovascular disease Dr. Rosenblum considers the potential of using Ketorolac injections directly at pain sites rather than intramuscularly Upcoming Courses and Conferences Ultrasound courses in New York and Costa Rica (check unwrappedpain.org) Private ultrasound sessions available Dr. Rosenblum will be speaking at Pain Week about ultrasound in pain practice and PRP Presenting at a primary care conference in London Teaching ultrasound at ISPN LAPSES conference in Chile (Dr. Rosenblum won't attend this year) Ketorolac Injections: An Effective Alternative for Musculoskeletal Pain Management Musculoskeletal conditions such as bursitis, adhesive capsulitis, and osteoarthritis affect millions and often require injectable therapies to reduce pain and inflammation. Traditionally, corticosteroid injections have been the mainstay treatment. However, concerns over side effects like tendon rupture, cartilage damage, and systemic hyperglycemia have prompted exploration of alternatives. A recent narrative review by Kiel et al. (2024) highlights ketorolac—a parenteral nonsteroidal anti-inflammatory drug (NSAID)—as a promising substitute for corticosteroids in musculoskeletal injections. Warning: OFF Label use of Ketorolac discussed. Please consult your physician. See full article  for details. Subacromial Ketorolac Injections for Shoulder Pain Subacromial bursitis and impingement syndrome are common causes of shoulder pain and disability. Several randomized controlled trials have shown that subacromial ketorolac injections provide pain relief and functional improvement comparable to corticosteroids: Goyal et al. demonstrated significant reductions in pain scores after subacromial injection of 60 mg ketorolac versus 40 mg methylprednisolone, with no difference in outcomes between groups. Taheri et al. found similar short-term pain relief at 1 and 3 months with either ketorolac or corticosteroid subacromial injections. Kim et al. reported equivalent clinical improvement in rotator cuff syndrome patients receiving ketorolac or triamcinolone injections. Min et al. noted ketorolac led to better forward flexion and patient satisfaction at 4 weeks compared to corticosteroids. These studies support ketorolac as an effective agent for subacromial injection, offering an alternative for patients where corticosteroid use is limited. Intra-articular Ketorolac Injections for Adhesive Capsulitis and Osteoarthritis Adhesive capsulitis (frozen shoulder) and osteoarthritis of the hip, knee, and carpometacarpal joint are often treated with intra-articular corticosteroids. Ketorolac injections have shown comparable efficacy in these conditions: Akhtar et al. found intra-articular ketorolac significantly reduced shoulder pain at 4 weeks in adhesive capsulitis compared to hyaluronic acid. Ahn et al. reported similar pain relief between intra-articular ketorolac and corticosteroid injections in adhesive capsulitis, with ketorolac providing superior shoulder mobility at 3 and 6 months. Koh et al. showed that adding ketorolac to hyaluronic acid injections in carpometacarpal osteoarthritis resulted in faster onset of pain relief compared to hyaluronic acid alone. Park et al. observed equivalent functional improvements with intra-articular ketorolac or corticosteroids in hip osteoarthritis. Jurgensmeier et al. demonstrated similar symptom improvement at 1 and 3 months post-injection for ketorolac and triamcinolone in hip and knee osteoarthritis. Xu et al. and Bellamy et al. confirmed ketorolac's comparable pain relief and functional benefits to corticosteroids for knee osteoarthritis, with ketorolac being more cost-effective. Lee et al. noted quicker pain reduction with intra-articular ketorolac combined with hyaluronic acid versus hyaluronic acid alone in knee osteoarthritis. aSafety and Pharmacologic Considerations Ketorolac's anti-inflammatory action stems from cyclooxygenase inhibition, reducing prostaglandin synthesis. Its half-life is approximately 5.2–5.6 hours, and it is metabolized in the liver. Unlike corticosteroids, ketorolac avoids systemic hyperglycemia and cartilage damage risks. Animal and in vitro studies suggest ketorolac may protect cartilage by inhibiting inflammatory cytokines. While gastrointestinal, renal, and cardiovascular risks associated with NSAIDs remain considerations, localized intra-articular and subacromial ketorolac injections may limit systemic exposure and adverse effects. Mild, transient post-injection pain has been reported but resolves without intervention. Conclusion Ketorolac injections, administered intra-articularly or subacromially, are a safe, effective, and economical alternative to corticosteroids for managing common musculoskeletal conditions. Their comparable efficacy in reducing pain and improving function, combined with a more favorable side effect profile, makes ketorolac an appealing option for clinicians and patients alike. Further research is warranted to fully elucidate long-term safety and optimal dosing strategies. FAQS Ketorolac Injections for Musculoskeletal Conditions: Frequently Asked Questions Musculoskeletal pain from conditions like bursitis, adhesive capsulitis, and osteoarthritis often requires injectable treatments. Ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), is emerging as a promising alternative to corticosteroids. Below are common questions and answers based on a recent narrative review by Kiel et al. (2024). 1. What is ketorolac and how does it work? Ketorolac is a parenteral NSAID that reduces pain and inflammation by inhibiting cyclooxygenase enzymes, which decreases prostaglandin synthesis. It can be administered orally, intramuscularly, intravenously, or by injection directly into joints or around bursae. 2. How effective is ketorolac for musculoskeletal conditions? Studies show ketorolac injections provide significant pain relief and functional improvement comparable to corticosteroids in conditions like: Subacromial bursitis and shoulder impingement (subacromial injections) Adhesive capsulitis (frozen shoulder) (intra-articular injections) Osteoarthritis of the hip, knee, and thumb carpometacarpal joint (intra-articular injections) 3. What evidence supports subacromial ketorolac injections? Randomized controlled trials found: Goyal et al. and Taheri et al. reported similar pain reduction and functional outcomes between ketorolac and corticosteroids for subacromial injections. Kim et al. and Min et al. observed comparable or better patient satisfaction and shoulder mobility with ketorolac versus corticosteroids. 4. How does intra-articular ketorolac compare to corticosteroids for adhesive capsulitis? Akhtar et al. showed ketorolac reduced shoulder pain more than hyaluronic acid. Ahn et al. found ketorolac and corticosteroids equally effective for pain relief, with ketorolac providing better shoulder mobility at 3 and 6 months. 5. What about ketorolac for osteoarthritis? Ketorolac combined with hyaluronic acid provided faster pain relief than hyaluronic acid alone in thumb carpometacarpal joint osteoarthritis (Koh et al.). Intra-articular ketorolac had similar efficacy to corticosteroids in hip (Park et al., Jurgensmeier et al.) and knee osteoarthritis (Bellamy et al., Xu et al.). Ketorolac injections were more cost-effective compared to corticosteroids (Bellamy et al.). 6. Are ketorolac injections safe? Ketorolac's side effects are similar to other NSAIDs, mainly involving gastrointestinal, renal, and cardiovascular risks. However, localized intra-articular and subacromial injections may reduce systemic exposure. Animal studies suggest ketorolac does not harm cartilage and may protect against inflammatory damage. Mild, transient local pain post-injection is possible but usually resolves without treatment. 7. What are the limitations of ketorolac use? Ketorolac is not suitable for patients with: Renal impairment Gastrointestinal ulcers or bleeding risk Cardiovascular disease or hypertension NSAID hypersensitivity, especially in asthma or chronic urticaria patients Clinicians should assess individual risks before choosing ketorolac injections. 8. How does ketorolac's pharmacokinetics affect its use? Ketorolac has a plasma half-life of about 5.2 to 5.6 hours and is metabolized in the liver. Pharmacokinetics for subcutaneous or intra-articular administration are less defined but systemic absorption occurs. Its relatively short half-life supports repeated dosing if needed. 9. Why consider ketorolac over corticosteroids? Ketorolac avoids corticosteroid-associated risks such as tendon rupture, cartilage damage, and steroid-induced hyperglycemia. It is also more cost-effective, making it a favorable option for patients and healthcare systems. 10. What further research is needed? More large-scale, long-term studies are needed to fully understand ketorolac's intra-articular effects, optimal dosing, and safety profile compared to corticosteroids and other treatments. Summary: Ketorolac injections, whether intra-articular or subacromial, offer a safe, effective, and economical alternative to corticosteroids for managing various musculoskeletal conditions. This makes ketorolac an important option in pain management and inflammation control.     Reference: Kiel J, Applewhite AI, Bertasi TGO, Bertasi RAO, Seemann LL, Costa LMC, Helmi H, Pujalte GGA. Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review. Clinical Medicine & Research. 2024;22(1):19-27. DOI: https://doi.org/10.3121/cmr.2024.1847 Disclaimer: This Podcast, website and any content from NRAP Academy (PMRexam.com) otherwise known as Qbazaar.com, LLC is  for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. Professionals should conduct their own fact finding, research, and due diligence to come to their own conclusions for treating patients. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.    

A large observational study found small but potentially meaningful differences in cardiovascular safety among sulfonylureas compared to DPP-4 inhibitors in type 2 diabetes, with glipizide showing a statistically higher risk of MACE. A separate study revealed that over half of advanced-stage lung and colorectal cancer cases involved missed diagnostic opportunities, highlighting systemic delays in workups and follow-up. Finally, the EchoNext deep learning model accurately predicted structural heart disease from ECG data alone, outperforming cardiologists and showing potential for scalable, cost-effective screening. These findings underscore the importance of individualized treatment, earlier cancer detection, and AI-enabled cardiac diagnostics.

Join Josephine & Jake on Love to Live Healthy as we dive into the truth about cardio!

Learn more about the role of Clinical Nurse Specialist, and how these individuals can drive positive outcomes for patients. Guest Laura Mack, MSN, RN, CNL, HF-CERT, PCNA's Heart Failure Prevention 2025 awardee, describes a nurse-led process improvements for patients with heart failure that yielded substantial progress in reducing rehospitalizations and mortality.PCNA Heart Failure Prevention Award: pcna.net/career-development/awards-grants/heart-failure- prevention-award/AHA Get With The Guidelines: heart.org/en/professional/quality-improvement/get-with-the-guidelines National Association of Clinical Nurse Specialists: nacns.org/about-us/what-is-a-cns/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Atsushi Sugiura, MD, PhD and Abdullah Al-Abcha, MD discuss transcatheter edge-to-edge repair in patients with primary tricuspid regurgitation.

Felix Lindberg, MD, PhD and Abdullah Al-Abcha, MD discuss revascularization strategies in ST-elevation myocardial infarction with multivessel disease - temporal trends, patient profiles, and outcomes.

Atsushi Sugiura, MD, PhD and Abdullah Al-Abcha, MD discuss transcatheter edge-to-edge repair in patients with primary tricuspid regurgitation.

Divaka Perera, MD and F. Aaysha Cader, MBBS, MD, MSc, FACC discuss the SERIAL study, the first randomized comparison of Fractional Flow Reserve and Instantaneous Wave Free Ratio in serial coronary artery disease.

Giuseppe Tarantini, MD, PhD and Mirza Umair Khalid, MBBS, MD, FACC discuss the Coronary Access After TAVI (CAvEAT) Study.

Mehdi H. Shishehbor, DO, MPH, PhD, FACC and F. Aaysha Cader, MBBS, MD, MSc, FACC discuss the analysis of 1-Year Outcomes of Transcatheter Arterialization of Deep Veins: PROMISE II and Pooled PROMISE Studies.

Felix Lindberg, MD, PhD and Abdullah Al-Abcha, MD discuss revascularization strategies in ST-elevation myocardial infarction with multivessel disease - temporal trends, patient profiles, and outcomes.

Mehdi H. Shishehbor, DO, MPH, PhD, FACC and F. Aaysha Cader, MBBS, MD, MSc, FACC discuss the analysis of 1-Year Outcomes of Transcatheter Arterialization of Deep Veins: PROMISE II and Pooled PROMISE Studies.

Divaka Perera, MD and F. Aaysha Cader, MBBS, MD, MSc, FACC discuss the SERIAL study, the first randomized comparison of Fractional Flow Reserve and Instantaneous Wave Free Ratio in serial coronary artery disease.

Giuseppe Tarantini, MD, PhD and Mirza Umair Khalid, MBBS, MD, FACC discuss the Coronary Access After TAVI (CAvEAT) Study.

Send us a message with this link, we would love to hear from you. Standard message rates may apply.We dive deep into recent research that challenges everything you think you know about daily step goals. The famous 10,000 steps target was actually a marketing gimmick from 1960s Japan with no scientific backing, while new evidence shows 7,000 steps delivers the most dramatic health benefits.• The 10,000 steps goal originated from Japanese marketing, not science• Meta-analysis followed 161,000 adults across 24 global cohorts for seven years• 7,000 daily steps reduced death risk by 47% compared to 2,000 steps• Walking 7,000 steps cut heart disease risk by 25% and cancer mortality by 37%• Dementia risk dropped 38% and depression symptoms decreased 22%• Fall risk in older adults reduced by 28% with optimal step counts• Most benefits occur transitioning from low to moderate activity levels• Cardiovascular benefits plateau around 7,000-8,000 steps• Diabetes prevention shows continued benefits beyond 10,000 steps• Adding 1,000-2,000 steps equals roughly 10 minutes of walking• Simple strategies include parking farther and taking after-dinner walksSupport the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski

With Edward Hulten, Brown University, Providence, and Islam Shatla, University of Kansas Medical Center, Kansas City, USA. Link to edi

In this episode, Kurt Strudwick, System AVP of Operations for the Cardiovascular Service Line at Virtua Health, shares how emotional intelligence, structural clarity, and community-centered innovation are transforming cardiovascular care. He discusses expanding access to advanced services, building team trust, and leading with a mission-driven mindset in today's evolving healthcare landscape.

Dr. Robert Baron reviews best practices in lipid management for preventing cardiovascular disease, with a focus on statin use. He outlines the strong evidence for statins in reducing heart attack and stroke risk by 25–33%, particularly in patients with clinical atherosclerotic disease, diabetes, or high LDL. He explains why shared decision-making is key in primary prevention, where guidelines vary and risk thresholds are debated. Baron discusses the shift to the newer PREVENT risk calculator, which offers improved accuracy and removes race as a factor. He also explains when additional lipid-lowering medications may be appropriate and clarifies the impact of risk-enhancing factors like family history, coronary artery calcium, and LP(a). [Health and Medicine] [Show ID: 40755]

Dr. Robert Baron reviews best practices in lipid management for preventing cardiovascular disease, with a focus on statin use. He outlines the strong evidence for statins in reducing heart attack and stroke risk by 25–33%, particularly in patients with clinical atherosclerotic disease, diabetes, or high LDL. He explains why shared decision-making is key in primary prevention, where guidelines vary and risk thresholds are debated. Baron discusses the shift to the newer PREVENT risk calculator, which offers improved accuracy and removes race as a factor. He also explains when additional lipid-lowering medications may be appropriate and clarifies the impact of risk-enhancing factors like family history, coronary artery calcium, and LP(a). [Health and Medicine] [Show ID: 40755]

In this powerful episode, I sit down with Dr. Jeremy London—a board-certified cardiothoracic surgeon with over 26 years of experience—to uncover the often-overlooked truths about cardiovascular disease, especially in women. Dr. London shares why menopausal women face triple the risk for heart disease, and what you can do to protect yourself. From the life-saving power of simply moving your body to the three essential tests everyone should be asking for, this conversation breaks down complex health topics into clear, actionable steps. Whether you're navigating midlife or looking to take preventative measures, this episode is a must-listen for anyone ready to take control of their heart health. About Dr. Jeremy London: Dr. Jeremy London is a Board-Certified Cardiothoracic Surgeon with over 26 years of clinical experience. He earned his medical degree from the Medical College of Georgia and completed his surgical training in Denver and Charlotte. A passionate advocate for patient education, Dr. London is on a mission to make health information more accessible through his newsletter, podcast, and social media. He lives in Savannah, Georgia with his wife and their three sons. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Caraway: www.caraway.com/neuro for an additional 10% off your purchase LMNT: Use code drinklmnt.com/neuro to get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase. MUDWTR - The coffee alternative. If you're ready to ditch the crash and sip smarter, go to mudwtr.com and use code NEURO to get 43% off + free shipping. David's Protein: Buy four cartons and get your fifth one completely free | Head to www.davidprotein.com/neuro Branch Basics: www.branchbasics.com to shop their Premium Starter Kit and save 15% | Code: NEURO *** Topics discussed: 00:00:00: Why women's cardiovascular risk triples after menopause 00:03:40: Two out of three Alzheimer's disease patients are women 00:04:47: What are lipid panels 00:05:20: Cardiovascular disease is the number one cause of death worldwide 00:06:13: The three buckets of heart disease 00:07:27: Cholesterol  00:08:47: ApoB 00:10:15: Plaque 00:10:53: Lp(a) 00:14:39: Louisa's mother's lab results 00:16:09: Going beyond lab work: Screen tests 00:17:39: Cardiac catheterization  00:19:49: Carotid ultrasound  00:21:07: What is atrial fibrillation and how is it diagnosed? 00:26:37: What you can do yourself to diagnose Afib 00:31:14: What was COVID like in the cardiovascular department? 00:35:47: Blood pressure 00:41:48: AI in the medical field 00:48:07: Exercise to minimize risk of cardiovascular disease 00:53:21: Healthy nutrition to minimize risk of cardiovascular disease 00:55:01: Can supplement eliminate plaque? 00:56:09: Changing our lifestyle and diet to mitigate diseases 00:57:31: Sleep quality to minimize risk of cardiovascular disease *** I'm Louisa Nicola — clinical neuroscientist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_

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Send us a textThe thought of losing our memories and cognitive abilities strikes deep fear in many of us. In fact, for people over 55, Alzheimer's disease has become the most feared diagnosis of all. But what if simple lifestyle choices could significantly reduce your risk?In this eye-opening conversation with dementia expert Lisa Skinner, we dive into the crucial differences between dementia (a collection of symptoms) and Alzheimer's (a specific brain disease). Lisa shares a powerful personal story about her grandmother that launched her 30-year career in dementia care, revealing how this devastating condition affects not just patients but entire families who essentially "lose their loved ones twice."The episode breaks down the risk factors into those we can't control (age, biological sex, genetics, and ethnicity) and those we can modify through lifestyle changes. Cardiovascular disease tops the list of modifiable risks, followed by diabetes, sleep apnea, and surprisingly, hearing loss. We explore why women face significantly higher risk than men—a complex interplay of hormonal changes, exercise habits, sleep patterns, stress management, and nutrition.Most compelling is the evidence that exercise has double the protective effect of brain games for preventing cognitive decline, while combining physical activity with mental stimulation triples the benefit. We discuss why proper sleep is non-negotiable for brain health, how strength training preserves cognitive function, and why supplementing with creatine monohydrate might be worth considering.With Alzheimer's cases projected to triple in the next 25 years, this conversation couldn't be more timely. The choices you make today directly impact your brain's future—and while nothing provides absolute protection, the science is clear that we have more control than we might think.Take charge of your cognitive future. Subscribe to learn more about how fitness truly is medicine for both body and mind.Support the showLearn More at: www.Redefine-Fitness.com