Podcasts about cardiovascular

This week we note and mourn the passing of pediatric cardiologist and thought leader Dr. Steven Lipshultz who passed on September 4, 2026. Dr. Lipshultz was one of the most significant cardiologists of the past half century and his contributions to the fields of pediatric cardiomyopathy, HIV cardiomyopathy and cardio-oncology were gigantic and meaningful. This week we turn back the clock and review a landmark work of Dr. Lipshultz from the Pediatric Cardiomyopathy Registry that was published in 2003 in the NEJM and we speak with 3 pediatric cardiomyopathy experts as well as friends and colleagues of Dr. Lipshultz - namely Dr. Neha Bansal of NYU, Dr. Daphne Hsu of the Albert Einstein College of Medicine and Dr. Joseph Rossano of the Children's Hospital of Philadelphia. Each shares their remembrances of this work and provide insights into the legacy of Dr. Lipshultz. doi: 10.1056/NEJMoa021715.

Hospitals and clinics continue to face a central challenge: extensive cardiac testing still fails to deliver clear, consistent diagnostic answers, slowing decision‑making and creating downstream operational and financial strain. In this episode, Jim Hartman, Chief Commercial Officer at Cleerly, examines with host Marilie Fouché how AI‑driven coronary CTA analysis strengthens diagnostic certainty, streamlines workflows across radiology, cardiology, and the cath lab, and supports more defensible adoption decisions for clinical and operational leaders. The discussion highlights practical evaluation criteria — clinical impact, workflow efficiency, and financial return — that executives can use to assess whether advanced imaging technologies can be integrated and scaled within their organizations. This episode is sponsored by Cleerly. ​ Learn how to identify AI trends by tracking where venture funding is flowing, and by listening to how leading CEOs describe risk and competitive strategy, download our free PDF report, "3 Ways to Discover AI Trends in Any Sector" at emerj.com/ait1  

On Season 12, Episode 2 of The LowDOWN: A Down Syndrome Podcast, Dr. Tessa Hilgenkamp gives us the lowdown on heart problems in people with Down syndrome.  Support the showThe LowDOWN: A Down Syndrome Podcast is produced by the Down Syndrome Resource Foundation. Learn more and support the podcast at DSRF.org.Follow @DSRFCanada on Facebook, Instagram, and Twitter.Leave us a rating and review on Apple Podcasts.

Join Alison Stephens, PA-C, as she defines PSVT (paroxysmal supraventricular tachycardia), explores its impact on patients' quality of life, and discusses various treatment options, including a new FDA-approved nasal spray.CE units are available for this episode only through June 15, 2027. To access CE, visit pcna.net/course/spotlight-on-psvt/.Related PCNA Resources:​​- Patient Journey: PSVT Strikes Anytime, Anyplace - https://pcna.net/resource/patient-journey-psvt-strikes-anytime-anyplace-video/​- PSVT: Barriers and Solutions to the Disease Burden for Patients - https://pcna.net/resource/psvt-barriers-and-solutions-to-the-disease-burden-for-patients/- Living with PSVT: A Patient-Centered Care Plan ​- Living with PSVT: Episodic Rapid Heart Rates - https://pcna.net/podcast/living-with-psvt-a-patient-centered-care-plan/Related Episode Resources:- Self-Administered Etripamil and Emergency Department Visits in Supraventricular Tachycardia - https://jamanetwork.com/journals/jamacardiology/fullarticle/2832045- Self-administered intranasal etripamil using a symptom-prompted, repeat-dose regimen for atrioventricular-nodal-dependent supraventricular tachycardia (RAPID): a multicentre, randomised trial - https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00776-6/fulltext- Catheter Ablation of Atypical Atrioventricular Nodal Reentrant Tachycardia - https://pubmed.ncbi.nlm.nih.gov/27754882/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This podcast episode explores transitions of care for patients with PSVT (paroxysmal supraventricular tachycardia), featuring insights from Alison Stephens, PA-C and Todd Wagner, RN. They discuss diagnosis, treatment pathways and the importance of patient education, follow-up care, and addressing social determinants of health to prevent recurrence and improve outcomes. CE units are available for this episode only through June 15, 2027. To access CE, visit pcna.net/course/spotlight-on-psvt/.Related PCNA Resources​​- Patient Journey: PSVT Strikes Anytime, Anyplace - https://pcna.net/resource/patient-journey-psvt-strikes-anytime-anyplace-video/​- PSVT: Barriers and Solutions to the Disease Burden for Patients - https://pcna.net/resource/psvt-barriers-and-solutions-to-the-disease-burden-for-patients/​- Living with PSVT: A Patient-Centered Care Plan - https://pcna.net/podcast/living-with-psvt-a-patient-centered-care-plan/​- Living with PSVT: Episodic Rapid Heart Rates - https://pcna.net/podcast/living-with-psvt-episodic-rapid-heart-rates-psvt-afib-and-more/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Guy Franklin, Principal and Co-Founder at All Aerobics Fitness, joins Kaz and Tubes to discuss the importance of cardiovascular fitness, explaining why getting your heart rate up regularly is just as important as strength training for long-term health and wellbeing.See omnystudio.com/listener for privacy information.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Michael Davidson is a world-renowned cardiologist, lipidologist, and the founding CEO of NewAmsterdam Pharma. He begins this episode by sharing how his family history shaped his interest in lipidology and primary prevention. He explains why prevention should focus on causal drivers of disease rather than near-term risk and examines the causal relationship between LDL and atherosclerotic cardiovascular disease. Michael then traces the complicated history of CETP inhibitors—from the original rationale that raising HDL would reduce cardiovascular risk to the failures of torcetrapib, dalcetrapib, and evacetrapib—and explains how lessons from these trials ultimately led to the development of obicetrapib. He reviews the phase 2 and phase 3 trials of obicetrapib, its effects on LDL-C, apoB, LDL particle number, and Lp(a), the ongoing cardiovascular outcomes trial, and where the drug could fit alongside statins and other lipid-lowering therapies. Peter and Michael discuss the relationship between statins and diabetes risk, then turn to the potential role of obicetrapib in Alzheimer's disease prevention, exploring the genetics of APOE4 and CETP, cholesterol metabolism within the brain, and emerging biomarker data. Finally, Peter and Michael explore the benefits of omega-3 fatty acids and the challenge of delivering DHA to the brain, as well as ongoing work on klotho in preparation for clinical trials. They discuss the potential for AI to transform clinical trials and the scientific and financial challenges of developing new therapies for cardiovascular and neurodegenerative disease. We discuss: Michael's path to lipidology, and his passion for primary prevention [3:30]; Reframing prevention around causal drivers rather than time horizon [9:30]; What CETP inhibition does, the evolutionary biology of CETP, the HDL-raising rationale, and Pfizer's torcetrapib failure [15:00]; Why raising HDL is thought to be beneficial, a quick review of the functions of HDL, and how this connects to torcetrapib [24:00]; The graveyard of CETP inhibitors: Roche's dalcetrapib, Lilly's evacetrapib, and Merck's REVEAL trial [27:15]; The causality of LDL in cardiovascular disease [34:30]; Reviving obicetrapib at NewAmsterdam, and confirming the benefit is LDL lowering: the TULIP data, the abandoned statin-intolerance path, and the Mendelian randomization verdict on HDL [37:30]; Phase 2 and phase 3 trials of obicetrapib—ROSE, BROOKLYN, BROADWAY, and TANDEM—and the PREVAIL outcomes trial, with the European and US approval paths [44:45]; Discordance among LDL-C, LDL-P, and apoB with CETP inhibition, and obicetrapib's Lp(a)-lowering effect [50:30]; Where obicetrapib fits in the lipid-lowering toolkit, the case against high-dose statins, and the problem of drug pricing [57:30]; The case for obicetrapib in Alzheimer's: the APOE4 and CETP genetics, the animal models, and funding Alzheimer's research [1:03:45]; Brain cholesterol metabolism and the APOE4 mechanism: the blood-brain barrier, astrocyte cholesterol efflux, the amyloid-tau cascade, the role of HDL, and why statins don't cause Alzheimer's disease [1:08:00]; The biomarker evidence: the CSF pilot study, Alzheimer's as a disease of middle age, the pharma graveyard problem, and the p-tau 217 results from BROADWAY [1:17:45]; Whether obicetrapib translates into clinical benefit for Alzheimer's disease: the risk of fooling yourself, the persistence of the amyloid dogma, ARIA in APOE4 homozygotes, and the next prevention trial [1:28:00]; Fish oil, EPA, and DHA: the cardiovascular trials and the challenge of delivering DHA to the brain [1:32:00]; Two open problems: using AI to reform clinical trials, and the statin–diabetes signal [1:41:15]; What it takes to develop a drug, the biotech investment landscape, and the klotho program [1:48:15]; Closing reflections: what to do if you carry APOE4, balancing motivation against over-testing, and the need for multiple therapies [1:55:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

PODCAST LAS NOTICIAS CON CALLE 14 DE SEPTIEMBRE - Arabia cierra importante oleoducto tras ataques, petróleo se dispara - FT Genera PR "no sabe" por qué 7 de 14 TM2500 están rotas - END AEE pide desestimar demanda de Power Expectations - El Vocero Carlo Linares (3PPO) va mañana a la Cámara - El Vocero $107 el barril de petróleo mientras el diésel en EEUU tocó un récord histórico de $6.23 el galón - Oil Price Guerra por frenar la IA: Amodei (Anthropic), Altman (OpenAI) y hasta Musk piden bajarle. Trump los manda a callar, Bannon y Bernie se unen - Axios Hoy voy pa' Martin's BBQDisfruta el mejor y más sabroso pollo asado a la varita de Puerto Rico.Comida fresca, saludable y sabrosa, con tus complementos favoritos: arroces, habichuelas, verduras, mofongo, tostones¡Esto sí es criollo!Ordena tu comida favorita para recoger o delivery través de Uber Eats o DoorDashMartin 's BBQ… una receta, un legado, una tradición¡Hoy como en Martin 's BBQ!Asado… Jugoso… sabroso#MARTINSBBQ #incluyeauspicio Power Expectations vendía que tenía el respaldo de bonistas de BlackRock y Apollo - End Sábado Ética confirma que AEE no consultó conflicto entre sus abogados y los de las APP+P - End Sábado "Congelado" el desarrollo energético: 54 proyectos atrasados - El Nuevo DíaDueños de Genera completan reestructuración: recorta ~90% de su deuda - El Vocero Desaparecidos 39 menores bajo custodia de Familia con paradero desconocido - El Nuevo Día Sobre 100 testigos en investigación contra Francisco Domenech, Itza García y Norberto Almodóvar - El VoceroMiguel Romero firma contrato de Escambrón, no sabemos cuánto pagará empresa por el canon de 60 años - El Vocero Proyecto para la pensión mínima de retirados del gobierno a mil pesos son 232 millones al año - El Vocero Junta cuestiona los 10 millones para arreglar 5 pozos de agua - El Nuevo Día EPA deroga los límites de carbono a las plantas eléctricas de combustibles fósiles9 muertes por influenza y 2816 casos reportados - El Vocero 43% de las casas abandonadas en PR tienen problemas de herencia - El Vocero Sacan jefe del Cardiovascular por traqueteos financieros y éticos - El Vocero Empiezan a demoler muelle de Roosevelt Roads para luego arreglarlo supuestamente para el 2029 - El Vocero Jefe de Desarrollo Económico viaja a Taiwán - El Vocero Con dos meses de verano ya empatamos el año entero de apagones - El Nuevo Día Junta exige facturas de educación especial tras verse que hay estudiantes que cuestan 577 mil al año en promedio - El Nuevo Día Trump pide a Ucrania parar ataques a refinerías rusas para bajar el precio del diesel - USA Today LOS DATOS DEL DÍACierre del viernes 11 de sept (los mercados de EEUU no operan fin de semana) + movimiento de crudo del fin de semana.Brent~$107/barril ▲ (salto por Arabia Saudita)Diésel (promedio EEUU)$6.23/galón ▲ récord históricoS&P 5007,656.98 ▲ +0.86%Dow Jones52,573.29 ▲ +0.98%Nasdaq▲ +0.88% (viernes; futuros CAEN el lunes ~1.5%)Bono 10 años4.96% ▲ (coqueteando con 5%)Hipoteca 30 años6.76%Dólaral alza (refugio + apuesta de alza Fed)

In this episode, Arun Kumar, MD, Director of the Division of Cardiovascular Medicine at MU Health Care, and Amy Begemann, Senior Director of Cardiovascular, Neuroscience and Ancillary Services, join the podcast to discuss their certification journey and the process behind achieving it. They also share insights on standardizing clinical processes and protocols to deliver more consistent, high-quality outcomes for patients.

On this episode of Vitality Radio, Jared breaks down CoQ10 and PQQ from the ground up. You'll learn how CoQ10 supports mitochondrial energy production, antioxidant defense, cardiovascular wellness, and healthy aging, plus why your natural production declines over time. Jared explains the difference between ubiquinone and ubiquinol, how age and digestion may influence which form makes sense, what to look for in a high-quality naturally fermented CoQ10, and how dosing can vary depending on your goals. He also explores how statin medications can affect CoQ10 levels and why PQQ may be the perfect partner by supporting mitochondrial biogenesis. Finally, Jared explains why both CoQ10 and PQQ earned a place in the latest Ultimate Vitality Multi formula.CoQ10, Ubiquinol, & PQQ Products DiscussedAdditional Information:255: Strolling Down the Costco Supplement Aisle. What to Look for on the Label Before Buying Your Supplements.662: Ultimate Vitality Multi: The Anatomy of a Premium Multivitamin667: Nattokinase vs. Statins: The Plaque Study You Were Never Told About613: Bad Medicine: Rethinking Cholesterol, Statins, and Heart Health449: Suppressive Medicine: How Big Pharma and FDA Get It Wrong With StatinsVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.This podcast is produced by DrTalks.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/podcast-service/

This week we take a step back in time 4 years ago to recall when we spoke with noted cardiovascular surgeon Dr. John J. Lamberti who is Associate Professor of Surgery at Stanford University. Dr. Lamberti's career has spanned from the time of Dr. Robert Gross in the 1960's to present day with Dr. Frank Hanley and the team in Stanford. His career perfectly mirrors the transition from the 'old days' of cardiac surgery up until the present modern age and he shares his reminiscences of working with Dr. Robert Gross, Dr. Aldo Castaneda, Dr. Maurice Lev, Dr. Roberta Williams, Dr. Nadas and others. He also shares his thoughts on how to be a good mentor and what that takes from someone who has mentored many surgeons in the past 5 decades.

Most drug discovery genomic data comes from a thin slice of the world, and that bias follows every decision downstream. Your team can run a Mendelian randomization study on 35,000 patients and still walk away with a single signal that doesn't even apply to the population you care about. If your phenotype definitions are fuzzy, more data won't save you. Erika Kvikstad is a computational biologist who led precision medicine for cardiovascular disease at Bristol-Myers Squibb, working on therapies including Camzyos for hypertrophic cardiomyopathy. She now works independently on genomic data equity, focused on how reference populations shape everything from target discovery to clinical trial recruitment. You'll get a practical look at how to evaluate real-world data vendors, why heart failure is nearly impossible to define cleanly from billing codes, and where statistical power breaks down even with tens of thousands of patients. Erika also explains how her team used AI to reconstruct missing imaging data and validate cardiomyopathy diagnoses at scale. This episode covers GWAS studies, Mendelian randomization, UK Biobank, proteome-wide analysis, and the practical gap between biobank-scale data and disease-specific cohorts. It's built for data and analytics leaders working in life sciences who need to understand where genomic bias enters their pipeline, not just that it exists. Clarification Around 57:58–58:24, in discussing the proteome-wide Mendelian randomization study, Erika moved quickly between two related findings. BTN3A2 was identified as a candidate associated with ischemic stroke and potential immune-modulatory biology. Separately, single-cell expression data helped contextualize other candidate signals, including some with enriched expression in cardiomyocyte populations. Cardiomyocyte-enriched expression was not a specific finding for BTN3A2. Chapter Markers 00:00 Whose genome are we designing drugs for 01:34 Erika's path from academic genomics to BMS 03:48 Building the precision medicine strategy at BMS 06:37 Ross shares his own HCM diagnosis 07:09 Why heart failure resists clean definition 11:11 How medication use reclassifies patients 14:35 Imaging as a biomarker, and its data gaps 20:23 Data infrastructure gaps across regions 22:44 What to look for when evaluating a data vendor 27:35 Consortia and biobanked specimens for rare mutations 29:52 Cardiovascular data infrastructure versus oncology 32:29 Where statistical power breaks down 37:07 UK Biobank's strengths and its limits 40:01 Bridging broad biobanks with disease-specific cohorts 44:32 How reference population bias propagates downstream 48:53 Where genomic bias hits hardest in the pipeline 53:18 Inside a proteome-wide Mendelian randomization study 59:42 Choosing the right computational tool for the question 1:06:38 Building globally representative genomic infrastructure 1:08:04 Ross's takeaways on bias and statistical power Useful Links & Resources - Erika on LinkedIn: https://www.linkedin.com/in/erikakvikstad - UK Biobank: https://www.ukbiobank.ac.uk - Alliance for Genomic Discovery: https://alliancegenomicdiscovery.org - SHaRe Registry (DCM Foundation): https://dcmfoundation.org Connect With the Show - Ross Katz on LinkedIn: https://www.linkedin.com/in/b-ross-katz/ - (Ross Katz on X: https://x.com/brosskatz - CorrDyn LinkedIn: https://www.linkedin.com/company/corrdyn/ Have you run into genomic reference bias in your own work? Tell us what it looked like and how your team caught it. Visit corrdyn.com to learn how CorrDyn can help your organization extract value from data. Subscribe to Data in Biotech so you don't miss the next conversation.

This episode of ASN Kidney Translation Podcast explores the ASN Kidney Health Guidance on the Cardiovascular-Kidney-Metabolic (CKM) Syndrome, discussing key recommendations, risk assessment, and strategies to improve kidney, heart, and metabolic outcomes.

Ladies, if you have ever been told your labs look normal while your body says otherwise, this one is for you. Dr. Amy Loden is a physician who nearly died from preeclampsia and now builds her practice around what medicine misses in women. She breaks down why pregnancy complications are a warning sign, what perimenopause is really doing to you, and why heart disease deserves your attention more than you think. You will walk away knowing what to ask for and why it matters.If you have any questions about this episode or want to get some of the resources we mentioned, head over to LesleyLogan.co/podcast https://lesleylogan.co/podcast/. If you have any comments or questions about the Be It pod shoot us a message at beit@lesleylogan.co mailto:beit@lesleylogan.co. And as always, if you're enjoying the show please share it with someone who you think would enjoy it as well. It is your continued support that will help us continue to help others. Thank you so much! Never miss another show by subscribing at LesleyLogan.co/subscribe https://lesleylogan.co/podcast/#follow-subscribe-free.In this episode you will learn about:How pregnancy complications reveal health risks that were already there.Why perimenopause symptoms get dismissed as normal aging.The heart disease signs that look nothing like the classic ones.Why good quality sleep matters more than hours in bed.How to eat and move to protect your metabolic health.Episode References/Links:Vitality Medical and Wellness - https://www.vitalitymwc.orgDr. Amy's TEDx talk on pregnancy - https://beitpod.com/amytedxDr. Amy Tiffany on Instagram - https://www.instagram.com/dramytiffanyDr. Amy Loden on LinkedIn - https://www.linkedin.com/in/amy-lodenThe Postpartum Pivot by Dr. Amy Loden - https://vitalitymwc.org/read-the-bookSubmit your wins or questions - https://beitpod.com/questionsGuest Bio:Dr. Amy Loden Tiffany is a St. Louis-based physician entrepreneur, author, and TEDx speaker dedicated to women's metabolic, hormonal, and cardiovascular health. After surviving severe preeclampsia and experiencing burnout in traditional, high-volume medicine, she pivoted her career toward a personalized, root-cause approach to patient care. As the founder of Vitality, she guides women through major life transitions—from postpartum to perimenopause—to help them recognize subtle warning signs and prevent long-term illness. Through her clinical work and her book, The Postpartum Pivot, Dr. Loden empowers high-achieving women to listen to their bodies, optimize performance, and take control of their long-term health.  If you enjoyed this episode, make sure and give us a five star rating and leave us a review on iTunes, Podcast Addict, Podchaser or Castbox. https://lovethepodcast.com/BITYSIDEALS! DEALS! DEALS! DEALS! https://onlinepilatesclasses.com/memberships/perks/#equipmentCheck out all our Preferred Vendors & Special Deals from Clair Sparrow, Sensate, Lyfefuel BeeKeeper's Naturals, Sauna Space, HigherDose, AG1 and ToeSox https://onlinepilatesclasses.com/memberships/perks/#equipmentBe in the know with all the workshops at OPC https://workshops.onlinepilatesclasses.com/lp-workshop-waitlistBe It Till You See It Podcast Survey https://pod.lesleylogan.co/be-it-podcasts-surveyBe a part of Lesley's Pilates Mentorship https://lesleylogan.co/elevate/FREE Ditching Busy Webinar https://ditchingbusy.com/Resources:Watch the Be It Till You See It podcast on YouTube! https://www.youtube.com/channel/UCq08HES7xLMvVa3Fy5DR8-gLesley Logan website https://lesleylogan.co/Be It Till You See It Podcast https://lesleylogan.co/podcast/Online Pilates Classes by Lesley Logan https://onlinepilatesclasses.com/Online Pilates Classes by Lesley Logan on YouTube https://www.youtube.com/channel/UCjogqXLnfyhS5VlU4rdzlnQProfitable Pilates https://profitablepilates.com/about/Follow Us on Social Media:Instagram https://www.instagram.com/lesley.logan/The Be It Till You See It Podcast YouTube channel https://www.youtube.com/channel/UCq08HES7xLMvVa3Fy5DR8-gFacebook https://www.facebook.com/llogan.pilatesLinkedIn https://www.linkedin.com/in/lesley-logan/The OPC YouTube Channel https://www.youtube.com/@OnlinePilatesClasses Episode Transcript:Amy Loden Tiffany, MD, MBA 0:00  If we're going to call pregnancy a stress test, which is becoming an increasingly common term, is pregnancy a stress test of a woman's metabolism and her cardiovascular system? Then we have to ask, what are we stressing it for? And the way I'm looking at this is a little bit different than how I was trained, which again was if you got the problem, the solution is in the pregnancy. So what if we started looking at pregnancy from the perspective of this is an unveiling, an unveiling of what was already there, and that nothing's actually gone wrong. Lesley Logan 0:29  Welcome to the Be It Till You See It podcast where we talk about taking messy action, knowing that perfect is boring. I'm Lesley Logan, Pilates instructor and fitness business coach. I've trained thousands of people around the world and the number one thing I see stopping people from achieving anything is self-doubt. My friends, action brings clarity and it's the antidote to fear. Each week, my guest will bring bold, executable, intrinsic and targeted steps that you can use to put yourself first and Be It Till You See It. It's a practice, not a perfect. Let's get started. Lesley Logan 1:11  Oh my God, Be It babe. Get ready. Get your notepad out. Get ready. If you're driving, listen. You're gonna re-listen. You're gonna share this episode with everybody. I am so freaking stoked about the guest that we have. I fell in love with her with every single answer, and we need women like this in the medical world. So Dr. Amy Loden is our guest today. We're going to talk everything from postpartum to perimenopause and heart health, because ladies, you can't be it till you see it if you get sick, cannot. And I know it's confusing. There's so much information out there in the world, and it's like, who do we trust? What do we do? And I'm just so grateful I found her, and you're gonna love it. So make sure you get ready to hit share on this episode for women in your life and the men who need to know about what women are going through. My mind is blown on the episode. Here's Dr. Amy Loden.Lesley Logan 1:54  All right, Be It babe, I'm excited. I'm super stoked. We're gonna talk about all things women, health-related, with an amazing professional person who actually studies this stuff, not what I've read, and then I'm asserting to you because I don't want to be that influencer. I think those people need to take a little step back and let the professionals do it. We have Dr. Amy Loden here on the show, who's going to tell us everything we need to know. But Dr. Amy, we tell everyone who you are and what you rock at, kind of how you got here.Amy Loden Tiffany, MD, MBA 2:20  Sure, thanks for inviting me. I'm happy to be here, Dr. Amy Loden. I am in St. Louis, Missouri. I help primarily women over 40, but certainly anyone who's like, "How are my hormones working for my life or not? How is my weight in the mirror matching the weight in my head or not?" And all the things that come with life transitions from postpartum to perimenopause, beyond, my goal is that women who've interacted with our team will have a better care experience because it's the care experience we want each of us to have had ourselves, and because each of us are not only professionals within the medical nursing communities, we're patients too, or daughters and sisters and mothers and neighbors and all the things. We know how much it sucks to be patient, right? And so we've tried to redesign what is the best thing for our ladies. Now, in full transparency, we do have a few dudes, but most of them have had their arms twisted by our rock-star ladies, and they are the ones that are coming because they're forced to. And eventually, they decide they like us, but we're pretty cool too. So that's who we serve, and that's what we do. And happy to go into any detail or rabbit hole you want to chase?Lesley Logan 3:21  Oh my God, Amy! I love that. When people ask about the people who listen to this podcast, we have mostly women and a few good men because there are some men out there, including my husband. They want to be interested. They want to. They want their partners, the women, their lives. They want to get what's going on. They don't want them to feel like an alien or like they're alone in this journey. So I think that's really, really cool. I also just want to highlight. I love that you brought up your patients too, because as someone who I feel very lucky to go through my perimenopause journey in today's time when people actually are talking about it, versus even 10 years ago, generations were not talking about this stuff, and I just feel it's really nice because then there's information I would never have known about HRT unless my girlfriend had told me about it. Oh, that could be going on, and then I could talk to someone. Can we go back though? Yeah, I feel like to be a doctor like yourself, who has empathy and understands, like you must have gone through a journey as well. You don't just want to do this Amy Loden Tiffany, MD, MBA 4:13  Because you wanted to do this. That's true. Lesley Logan 4:16  Maybe there are a few. There might be a few, but typically, like there there has there's a story there that got you to be like I want to care about this. So can you tell us a little bit more about that?Amy Loden Tiffany, MD, MBA 4:24  Absolutely, yeah. So definitely with the traditional college to medical school road, really didn't understand that there's a and I say this with all the love in my heart, but there is a bit of brainwashing to be a good doctor, right? And what is a good doctor was who you've been told it is. It's not necessarily an external criteria. It's who does academic medical center say, and that was very different. I learned through transferring all of my non-medical student fears into the actual application of those fears, and then being a patient and living those fears. That I realized there's a whole lot we're not talking about. There's a whole lot that we're not being told, both as doctors and as women, as patients, and it's hard to realize you don't know what you don't know if you've been told you're the expert and you know everything, right? And most doctors don't go around saying they know everything, but there's enough patients who feel like that's what's communicated, that that's the language I'm using.Lesley Logan 5:18  Yeah.Amy Loden Tiffany, MD, MBA 5:19  And that's really frustrating as a patient, so I didn't realize how frustrating though it was until I was a patient, and I'm a mom of five kids, my third and fourth are twins, and really I am so grateful to live in the United States in a time in history where complicated pregnancies does not mean that mom dies, because I developed severe preeclampsia with heart failure, and my twins came 31 weeks instead of at least 37, and I nearly died the night they were born. They nearly died the night they were born, and I just am grateful that God let me be in this situation that I had the help I needed. Historically, these are not good situations. We see this on TV and in movies frequently. And something like 70,000 women a year across the globe die of the same disease I had, preeclampsia. So it's not nothing, even in our day and age, in certain countries, and even in countries where you have advanced medical care and they do everything right. It can still happen. So, that for me was the pinnacle of this isn't working. What we're telling people to do isn't working because I had done all the things.Lesley Logan 6:30  Right, you were a doctor. You did all the things. I did all the things. You enjoyed all the appointments. You were probably doing, and this is your third and fourth. So you knew what it should feel like. You knew what you should be eating. You knew all the vitamins to take.Amy Loden Tiffany, MD, MBA 6:41  Correct, and it didn't work, right? It didn't work, and so I think that is the fundamental kind of if you place a pivot on why did I change how I think about healthcare as a doctor, it was because of my experience as a patient for myself. My husband had cancer twice, so being the advocate for him in those types of things, guiding my children and now my parents through healthcare, you start to carry a lot of stories, and you start to see, wow, they're not doing what I think is just the bare minimum. And if they're not doing that for me or for my family, I know they're not doing it for everybody else.Lesley Logan 7:11  Yeah.Amy Loden Tiffany, MD, MBA 7:12  And then at the same time, holding a ton of grace in my heart because that's—they're doing what they were taught.Lesley Logan 7:17  Right?Amy Loden Tiffany, MD, MBA 7:17  Right. And they can't do differently if they don't know differently. You can't be better if you don't know to be better.Lesley Logan 7:23  Yeah.Amy Loden Tiffany, MD, MBA 7:23  So that is a really tight tension. But I thought I would just keep plodding through and just be a better doctor in that context of me being a patient until a little—I guess it was two years later. My daughter at that time, my oldest, was seven, and I had about 3000 patients. I was working somewhere between 65 and 80 hours a week, and had four kids at that time. And my daughter came up to me one night, and I'm opening the computer. I'm doing work like I do every night, and she says, "You're gonna make my birthday gifts. Like, can I help?" Right, totally innocent seven-year-old looking forward to her birthday knows that her mom shops online, right? And so she's like, "I want to pick my birthday presents," and I kind of stared at her. I was like, "No, no, I'm going to work. We'll do that later," and go watch whatever show. It's probably Paw Patrol for all I know, right? That's in the background. Go watch it. It's gonna be bedtime soon. And she just stands there, and I haven't even looked at her at this point. My eyes are on my computer. I'm just telling her this as I'm going. I'm totally not in the moment, right?Lesley Logan 8:19  Of course, because like you have so many, you have 3000 patients and four kids.Amy Loden Tiffany, MD, MBA 8:23   I can't keep up. I can't keep up. Right? I'm barely getting enough sleep. I'm not exercising, and I'm just trying to survive. And she doesn't move. And so I remember not totally slow motion, but I remember turning to her and feeling like I was going to be like, "What?" Right? What do you need? And she's just got out of the shower, so her hair's wet. She's got her pink pajamas on, bright big blue eyes, and they're full of tears. And there are just silent tears tracking down her face, and I'm horrified. Oh my gosh, what's wrong? Right now, I'm in fix-it mode.Lesley Logan 8:55  Yeah.Amy Loden Tiffany, MD, MBA 8:55  And she still doesn't really budge, and she just says in a very sad voice, "Mommy. Why do you love your job more than me?"Lesley Logan 9:05  Oh.Amy Loden Tiffany, MD, MBA 9:07  Yes. So the twins tried to kill me. She did kill me, right? Like, that was a knife in my heart because nothing ever had I wanted to be better than a so-called good doctor than to be a good mom.Lesley Logan 9:17  Yeah.Amy Loden Tiffany, MD, MBA 9:18  And that was for me the moment that I realized I'm not doing either of these well, and I'm not showing up how I want to be personally or professionally. I'm certainly not taking care of my health. I'm not doing the things I'm telling my patients to do. Like, it was a moment where I really felt the failures. I felt all the feelings, and I told my husband that night, "This is not working anymore." And he actually thought I thought was talking about our marriage, and so he was like, "Oh my gosh, what's wrong with our marriage?" Right? No, but I need to, like, redo. We have to redo this. I either have to retire, or I have to do something different.Lesley Logan 9:51  Yeah.Amy Loden Tiffany, MD, MBA 9:51  And he was like, "You're not retiring. You will drive me crazy. Go find something different to do, and I will make sure our family is okay." And so I did. And this June will be five years of having Vitality here in St. Louis and serving women and trying to lean into all the pain and the things and the feelings they're dealing with from all the things and the feelings I dealt with having walked that path.Lesley Logan 10:13  Yeah. Oh, Dr. Amy, I love that you shared that whole story because I think there's so many women who are listening here and, like, they don't have, they may have one kid or they have no kids, but, like, I think we can all relate to, like, having just too much on the plate because.Amy Loden Tiffany, MD, MBA 10:27  Right.Lesley Logan 10:28  Hello, my high-achieving woman. I see you, everyone here listening. We call recovering perfectionists and overachievers. There's nothing wrong with being a high achiever, but what happens is we tend to just keep saying yes to things, and we're like, yeah, we can fit that one more thing in, that one more thing. All of a sudden, it just comes to, like, a volcano breaking point. Yes, and because we don't, we don't see the signs early that we are at the breaking point. We don't, you know, we, it's almost, it's actually proven to be not true. But everyone uses the frog in the boiling water, right? Like, we just kind of, like, you don't realize how hot it's getting until it's until your daughter is crying in front of you. Oh, exactly.Amy Loden Tiffany, MD, MBA 11:05  Yes, it was awful. I never want to relive that moment.Lesley Logan 11:08  Yeah, but also, like, thank goodness for her because that she felt brave enough to say that. Like, what a badass she is. I mean, she's just going to be, like, she's just going to be a girl who speaks her mind. She does.Amy Loden Tiffany, MD, MBA 11:18  She's 13 now, and she heard me tell that story once, and now she's like, "Well, you have to credit me for opening your business because I hadn't said what I did." I was like, "Won't you just tone it down a notch, please?"Lesley Logan 11:27  It's called balance, babe. It's called balance. Yes. Okay. So, can we, like, let's get to some of the health stuff that I think our listeners want to—I want to definitely get into perimenopause, but I do want to, because we started with a pregnancy, and I have had family members who, you know, have had preeclampsia in their, and it's scary. So, how are pregnancy complications connected to long-term heart risk? I don't think anyone's thought about that. I just thought, like, if it's because I don't have kids, like it's going to screw up your pelvic floor, and you might have to rebuild your abs and these other things. But I didn't know it can affect your heart long term.Amy Loden Tiffany, MD, MBA 12:01  I had no idea. I'm so glad you brought that up. So I actually did a TEDx talk on this very topic, where the idea is pregnancy is so much more than just the birth of a kid. That's how we think about pregnancy in our culture. That's even how we think of it medically, right? Like if you have preeclampsia, you have gestational diabetes, you have high blood pressure, whatever in pregnancy, the answer is end the pregnancy, deliver the kid if they're old enough, right? Like, get, move it along and it's gone. But that I strongly believe is not true. We can't test this in a lab, so you have to do a little bit of extrapolation here. But if we're going to call pregnancy a stress test, which is becoming an increasingly common term, is pregnancy a stress test of a woman's metabolism and her cardiovascular system? Then we have to ask, what are we stressing it for? And the way I'm looking at this is a little bit different than how I was trained, which again was, if you got the problem, the solution is in the pregnancy. So, what if we started looking at pregnancy from the perspective of this is an unveiling, an unveiling of what was already there, and that nothing's actually gone wrong. It's scary. It's horrifying. And yes, absolutely, people die. So how can I say nothing's gone wrong? What I mean is nothing has gone wrong in the context of the situation we put your body in. It's exactly responding the way it should for the context it's in. So if I have underlying insulin resistance, and then I put a pregnancy on top of that or perimenopause, and I'm starting to have more insulin resistance. Well, of course I'm going to develop gestational diabetes. If I'm having a lot more fluid retention and I'm putting up a low weight, of course my blood pressure is going to go up, right? If I've got underlying inflammation, of course preeclampsia is going to develop. So I think we need to stop and think about it as it's not done; it is unmasked.Lesley Logan 13:42  Got it. Amy Loden Tiffany, MD, MBA 13:42  And then once you know it's unmasked, you treat it.Lesley Logan 13:45  I see. I see. Because again, we think of pregnancy as just the baby, so you have the baby, but it's well, but there's a problem, an underlying problem that the pregnancy revealed is what you're saying. And so great if having the baby is the safest thing for both people, we do that. But also, you still have this underlying issue.Amy Loden Tiffany, MD, MBA 14:01  Yes, it's still there. Correct.Lesley Logan 14:03  Yes, and I don't think anyone does that. I think they're just, "Okay. Now you don't have gestational diabetes anymore." But I have had clients who had it, and then afterwards, so what do we got? Oh, I'm fine. Are you correct? I don't think so. I'm not a doctor, but they're not fine. Don't just be diabetes. Yeah, for a moment. Yes.Amy Loden Tiffany, MD, MBA 14:19  So I actually experienced this as a patient too. I went in after my first pregnancy with gestational diabetes. At the time, I was living in New York City. I walked everywhere. I was a normal weight. I ate pretty clean, and despite being in residency, I'd got decent sleep. I didn't have any other kids. It's my first kid, so I got decent sleep. Right, but I had the baby after having had gestational diabetes. I go see my OB, and she's, "Oh, just follow up with your primary doctor." I go see my primary doctor, and he's, "Your weight's normal, your labs are normal. We're done," and that is how I was trained too. So again, lots of love in my heart. They're not; they're just not told. But for more than 10 years, we've known that women who have these high-risk pregnancies are at high risk not just for diabetes, but heart disease, stroke, kidney failure, dementia. Listen, I can't treat dementia well in the clinic, right? So why wouldn't I want all hands on deck trying to prevent it?Lesley Logan 15:07  Yeah.Amy Loden Tiffany, MD, MBA 15:07  But that's not how our medical professionals are trained—nurses, advanced practice providers, any of them. And so we're asking people and expecting people to fill in a gap they don't know exists, and so all these reproductive-age women are falling into it. And then where it gets really interesting is some of the same things you have immediately postpartum in all your different types of hormone fluctuations are matched intermittently for 10 to 15 years before menopause when you're in the perimenopausal years.Lesley Logan 15:32  What?Amy Loden Tiffany, MD, MBA 15:33  Correct, but that's why these women are feeling, "I'm going to my doctor, I'm putting on weight, I'm doing all the things, it's not working," and they're being gaslit, partly because their doctors don't know what they don't know, and partly because we're not acknowledging this is the same physiologic status of hormones that are different than baseline. So we're not in a country, and we don't have the testing that would promote or facilitate checking what is your normal hormone level at 18, so that we know what 18 should look like, and then by 45, you know, we're not. So we're trying to patchwork together a whole bunch of tests, and different labs have different testing, and different people say different things about testing. It's very confusing.Lesley Logan 16:10  Yeah.Amy Loden Tiffany, MD, MBA 16:11  And you end up with women suffering. And at the end of the day, that's the problem I'm trying to solve: is how do we stop these women from suffering? Because they are called to live big lives, to be ambitious for a purpose, for a calling. They have a lot to do, and their health is one of their biggest assets. It should not be a liability.Lesley Logan 16:27  Yeah.Amy Loden Tiffany, MD, MBA 16:27  And that's what's happening, especially for women who are trying to not work just in the home but outside the home. Right? There's a lot they're carrying. Yeah. So that's, I don't remember. Sorry, I'm having a total perimenopause moment. I don't remember where we started with that question here. I'll stop there. Lesley Logan 16:42  Don't worry, babe. I got my focus meds on the ADHD today, so I'm tracking. So we're good. But we were talking about the postpartum, and then we got into those hormones that switch as, and they can repeat into perimenopause. And I think this is fascinating. I love that you brought up. It doesn't matter if you're in the home or out of the home. We have big lives. Correct. We can't have our health be a liability, and I think for a lot of us, it feels like, like my girlfriend's a weight-loss coach for women over 40 who feel like their body gave a middle finger. That's what her coaching is, and it's all about not going to yo-yo diet. That's not going to work. We have to figure out what is the underlying issues, and it can only go so far because you said we don't test our hormones at 18. We don't do that, so we don't know what is normal for us, and I remember I was having a lot of health issues, digestive issues in my 30s, and no doctor could help me. In fact, one doctor sending me to, I was in this weird part where they study HIV and Ebola in the hospital, and she's like, "Do you know why you're here?" I don't know why I'm here. I don't. This scares the hell out of me. This feels like a department I should not be in. I'm not in any pain. I feel like I'm taking someone's spot, and so because he could, he just couldn't figure out what's going on my stomach. So I found someone who did an actual test of everything. He's so range normal. We don't know what normal is for you. We just know what the average person of this population of people that who knows who they were that were tested. So what is normal for you might not be the average. And I was, "Oh well, that's the first time anyone said anything that makes sense. That's the first time." So you can be in range, but for your hormones, but it wasn't in range for you because maybe you were used to higher testosterone, you're used to higher things. And so I love that people like you exist. I'm sorry for the frustration of your own journey, but also without people like you, women like me wouldn't have someone going, "Hey, actually, maybe you should be on testosterone right now," even though the, this is what it is. Mine was actually zero, but people, you know, we can actually get you help because I feel so much better because someone finally was listening to me and thought, "Yes, we're not going to compare you to a random person. We got to compare you to how you're used to feeling."Amy Loden Tiffany, MD, MBA 18:42  Correct. And for most people, that can't happen in the traditional system.Lesley Logan 18:47  Yeah.Amy Loden Tiffany, MD, MBA 18:47  You can't do that in a 10-minute visit.Lesley Logan 18:49  Right.Amy Loden Tiffany, MD, MBA 18:50  You can't do it when your doctor has 3000 patients, 10-minute visits, and they really don't actually know who you are.Lesley Logan 18:55  Yeah.Amy Loden Tiffany, MD, MBA 18:56  You just can't. So we've got a little bit of unrealistic expectations as a society, and then you know any women's magazine or journal article you read says, "Talk to your doctor about this." So then you go in, I'm all prepared. I have my list. I've done it too, folks. Right? This is not a criticism, but they, they can't. They don't have the ability to process it, and the way they're paid is based on the questions they ask you for insurance. So every incentive is misaligned, and at the end of the day, women, people are being screwed.Lesley Logan 19:22  Yeah, yeah. No, it's so true. So I'm glad we talked about the postpartum. I want to get into now. We're in the perimenopause, and yep, this is hard because you mentioned the hormone shift of people after postpartum is its own crazy world. I keep checking on my sister-in-law every day. How are you feeling? Are you feeling okay? Right. You feel okay? She's, "I'm fine." Are you fine? Let me just, I just want you to know. It's okay if you feel different, right? I think I'm crazy, but I know that that people don't realize how they're feeling, and it's hard to get to the doctor until it's too late. So I'm just, I'm on her. But for people like me, we didn't have children, so we have never experienced a crazy shift. We just start to experience, "I don't feel like my, anymore," and all the symptoms are so different for every single person. I'm not having hot flashes, but I'm, I got to keep my hair still here. But my inflammation was insane. I was putting on weight and working out and eating the same. And I don't understand what's going on. You know, so can we talk a little bit about what, I don't know where you want to start with that. So you tell me where you want to start with my post, my perimenopausal people who are not necessarily attributing these changes to that.Amy Loden Tiffany, MD, MBA 20:27  So I think the biggest confusion I see in the exam room conversations is that there's just question of, am I in perimenopause or not? And it's more of a less of a yes-no and more of, are you on the spectrum, and where on the spectrum are you? And so if you think of it as a sliding scale, because some months those ovaries are working really great, and you feel all the feels, and you're 18 again, but a lot of months maybe you're more like 20 or 25, right? And then maybe out of the blue, I feel like I got run over by shock. Nothing's working for two or three months, and then we're back to 25, right? And so it's ups and downs. You're like, what is happening? It is a roller coaster, and it runs anywhere from 10 to 15 years before you actually go through menopause. So I think of it as reverse adolescence, and I think it's completely ironic that God lets us have teenage girls when moms are going through perimenopause because that is just double-adolescence whammy, right?Lesley Logan 21:19  And no wonder, no wonder marriages don't survive certain things. Right, you have a daughter going through puberty and a wife with a pair of menopause. Good luck to the husband. Correct, becauseAmy Loden Tiffany, MD, MBA 21:28  I want to have sex. I don't want to have sex. I have pimples all over my face. I don't want to go to the house. I do. My belly's bloated. It's not like my mood's up. All the things, and it's all in reverse. So it's a it's a period of a woman's life that I think needs to be acknowledged, and then within the healthcare system, there's more noise about it over the last five years. You're seeing more and more people talk about this, but there's not a lot of standardization, and so you're getting chiropractic, functional medicine, traditional medicine. You're getting all sorts of different recommendations. So my hope is that over the next decade, we start to see some standardization, and we start to say this is what is normal for this population. You still have to apply it to the person. You cannot take population data and apply it to individuals and say that you're going to have good luck, bye. We'll see you in a year. That doesn't work. What I do think is that women need to know what's normal for that time, and then they need to decide, do they want to do something about it beyond what their body is experiencing? And here's some really interesting data that I hope your listeners suddenly stop and listen. If they don't hear anything I've said yet, this will be really important for women who have hot flashes and night sweats. Either one, they're actually the same thing. We call them vasomotor symptoms. When you have those at a certain degree, so that they're happening most days of the week, more than 10 times a day would be an easy target to kind of pay attention to. You have that, and you choose not to take hormones. You actually have an increased risk for cardiovascular disease and stroke. That does not mean every woman in that category can or should take it. There may be reasons they can't, but the hormones we use today are different than what in the Women's Health Initiative that came out in the early 2000s. So you're getting a lot of confusion because women are reading about data from that, not realizing that it has changed, and that study is not going to be redone. It was a huge study. We're not going to see data like that, so we have to make really informed decisions. But cardiovascular disease, hear me, ladies. Cardiovascular disease, which includes stroke and heart failure, kills more women every year than all your cancers combined. Yeah, I get the women and they come in religiously for their mammograms or their Pap tests, right? But they don't know that the bigger risk is that they're going to die of heart disease, cardiovascular stroke, and we know that one in eight women, roughly, have breast cancer risk, and those women get it. One in two women are getting heart disease. So there's one inLesley Logan 23:50  Two.Amy Loden Tiffany, MD, MBA 23:51  One in two. So that means there's two of us on this call, right? We already know I'm going to get it because I had preeclampsia. So I'm the one. Lesley Logan 23:56  I was going to say. I hope it's not maybe. I hope it's not you. But, like, thank God you know that because I think it's one and two, especially if you don't know. Because if you know that you're at risk, you do. Then you can you do something. I am. I'm double the risk for breast cancer, so I have to do an MRI and a mammogram every six months, and I have some decisions I might have to make in my life. But because I know.Amy Loden Tiffany, MD, MBA 24:18  Right, I can take.Lesley Logan 24:20  I can take action. Yeah, correct.Amy Loden Tiffany, MD, MBA 24:22  And you know, using that same kind of history, if someone comes in my office and says that I don't want to take hormones because I was a breast cancer, I'm like, that's fine. But let's look at all the facts. Let's lay it out like your financial advisor does, and then you can make an informed decision. Because just acting out of fear or reacting is not wise either.Lesley Logan 24:38  I actually really appreciate you mentioning that because it's true. If I'm, I'm very lucky in that I still get to do the HRT that I'm on, even with my risk. But also they're checking me every six months, and I'm checking me. So if anything's going to happen, we're going to catch it so much more quicker. Whereas the hard stuff, there's only so much you can do with that. And so if you're, especially if you're not aware. Say there's all conversations, but I liked the way you laid it out with the wealth manager. I just met with mine. He laid out here's where we're being aggressive. Here's where we're doing this. Here's what's going on here. We're going to move this over here because we're going to risk-manage these risks. And I think that's that's a better way to look at it because we're not going to, every single one of us is unfortunately going to experience something because it's a body. We're not a machine. Amy Loden Tiffany, MD, MBA 25:21  It wears out.Lesley Logan 25:22  I did not know it was one in two, girl.Amy Loden Tiffany, MD, MBA 25:26  Yeah, and what's even more disturbing, you may have heard a lot of women have by now that women's heart disease presents differently than men.Lesley Logan 25:32  Yeah, can you tell us just in case my people haven't heard because I didn't know it was one in two? So let's go over the signs.Amy Loden Tiffany, MD, MBA 25:38  A lot of times people think of what's the so-called traditional? It's the jaw pain, the radiation of pain from your chest up to your jaw, to your back, down your left arm. Very classic symptoms. Classic because it was studied in men, and then we have these so-called atypical for women because they're not typical compared to men, but they're classic for women. And so, got a little bit of lingo here that it doesn't make total sense. But for women, sometimes it's they just feel a lot more anxious than they've been for unclear reasons. They have this sense that something bad is on the horizon. They can't really place why their sleep is different. Maybe they're having some shortness of breath they didn't used to have. Maybe they go up the stairs in their house, with a laundry basket, and they're huffing and puffing when six months ago they weren't. So it can be very subtle differences. It could be a new fatigue. Check labs are normal, but the fatigue's still there. That worries me when I hear women say this. Unfortunately, the number one sign that you have heart disease is sudden death.Lesley Logan 26:33  Oh.Amy Loden Tiffany, MD, MBA 26:34  So let that sink in for a second. So we can't always wait on what the signs are.Lesley Logan 26:39  Yeah, we can't fix that. Right. Correct. Okay, so that's hard because our signs are also. I feel like high-achieving women would so easily brush away that anxiety.Amy Loden Tiffany, MD, MBA 26:51  All the stuff. Correct. Because I have a lot of tabs open.Lesley Logan 26:54  Yeah, I got this going on, or I haven't been working out, so of course I'm out of breath going up the stairs. They would just so easily.Amy Loden Tiffany, MD, MBA 26:58  It's May, it's graduation season. It's wedding season, right? This is just aging, and that's not the story at all. The problem is 10-minute visit with your doctor who has 3000 patients. They don't know who you are. They're not going to notice that this is different for you.Lesley Logan 27:13  Yeah.Amy Loden Tiffany, MD, MBA 27:13  Decreased exercise tolerance is a big one. And so, if you could walk three miles every day in your neighborhood, now you're like, "Wow, I'm really struggling to get through one." I'm worried about that. I want to know what's going on and why.Lesley Logan 27:25  Yeah. So I guess since one getting a 10-minute visit is hard. I, where I live in, I live in Las Vegas. Last I heard, we are short general practitioners by 1400. I don't have one. I go to a women's clinic, and I'm really grateful. It's a, it's also a student-teacher thing. So I actually, they've caught things because the students are asking the questions because they'reAmy Loden Tiffany, MD, MBA 27:44  Yes, yes.Lesley Logan 27:46  I love them. I'm so grateful for them, but are there things that women can do to check their heart, or is it just being, is it just noticing the one mile versus a three mile? What can we, what are the signs we need to be checking on?Amy Loden Tiffany, MD, MBA 27:57  Certainly be aware of what your body is telling you. Again, if you have to remember nothing else, this is another one: is that your body is smart; it will talk to you, but you have to listen.Lesley Logan 28:05  Yeah.Amy Loden Tiffany, MD, MBA 28:06  So that's really essential. If something's different, say something. You're right. There's a big collapse, if you will, of how much support we have in healthcare, whether it's nurse practitioners or chiropractor or whatever. And the issue is not all of them are trained the same way. So when I worked in the OB/GYN clinic, it became apparent to both of us, on both sides of it, that OBs know stuff about women's health. I don't know, but I know stuff about metabolic and heart health that the OBs aren't taught, and most women use their OBs as their primary care, at least to a certain age.Lesley Logan 28:32  Right.Amy Loden Tiffany, MD, MBA 28:33  And again, you don't know what you don't know, so you don't realize what you're not looking for that you should be. And our system's not set up for good collaboration. So if I could tell women, here's a checklist of things I want to make sure you get, your doctor is going to give you some resistance, most likely because they don't realize that lipoprotein with a little a, it's like in parentheses at the end of it, not the big A. Lipoprotein little a. If you have that mutation, and 10 to 20% of our population does, you have a different rate of plaque development, at least risk for that than the average risk will miss. If you have high insulin levels, you have a higher risk that you're going to be on a pathway toward diabetes. Those are not things that are standard checks. So knowing that there's other tests you can ask for, and even if your insurance doesn't cover it, they're not expensive tests. Just get it once, right? Have an idea of what's going on in your body once gives you a ton of information. I offer a lot of our patients to wear different glucose monitors, even if they're not on diabetes. And all my physicians who are listening to this are probably like, "You do what?" But the reason is, if you can figure out that your glucose and insulin are high before you develop diabetes or pre-diabetes, if you figured out that insulin-resistant stage, that's a lot easier to fix, and our doctors aren't even taught about what is insulin resistance, what is the criteria for it, and how do we reverse it?Lesley Logan 29:47  Right, because there's some prevention we can do if we have information.Amy Loden Tiffany, MD, MBA 29:50  There's a ton, and it's things women can do in their homes or their businesses. It's not stuff I'm doing in the exam room.Lesley Logan 29:56  Yeah, and that's also, you know, you're listening to this podcast, you're kind of a go. Anyway, so you're gonna, you'll take the action. Our health insurance is very bizarre. I thought it was crap because, but it has a lot of preventative stuff that goes on with it. Hey, we want to put this thing in your house and check your heart and some other levels every, I don't know, two or three times a week. They keep calling them. I have two adults. We have two ADHD adults in this household. The box is here. One of us will open it when it becomes the pressure. I just have to hang tight. We'll get there. But I'm really impressed by that because we don't have access to a regular doctor. So what information can we gather so we could be watching it and monitoring it? So we can advocate for ourselves if something comes up. So having that prevention is really amazing. Okay, so we talked a little bit about the perimenopause and the different things. What are some simple shifts that women can make now to protect their future? I mean, obviously we have a wide range of women, so the now is different. But what are some things that they could be doing? Because I do think that they are getting information from the magazines and the Instagrams, and we should get it from the person who's experienced it and has seen it. You know, so you.Amy Loden Tiffany, MD, MBA 31:00  Some easy things, and I say easy relative because they're easy to do, which means they're easy not to do. So acknowledging that, right? It's real. Number one, understanding that just because you get eight hours of sleep, if they're not high-quality hours, you've got a metabolic risk from your sleep not being normal. That's important to understand because you spend a third of your life asleep, right?Lesley Logan 31:19  What's a metabolic risk? Just in case my people. So.Amy Loden Tiffany, MD, MBA 31:22  If you don't get good-quality sleep, your cortisol goes up. It's one of your stress hormones, and when cortisol goes up, glucose goes up. When glucose goes up, insulin goes up. Insulin's your fat-storing hormone. So even without your sex hormones being involved, or the ghrelin and leptin you're hearing about with weight and GLPs and all that, just those, you're not getting good sleep. It's going to be a problem. Insulin resistance is going to go up. Insulin resistance means your cells are not listening to the insulin your body is giving it, so your body works harder to get more insulin, and the cells work harder to ignore it, and it just keeps going in a vicious cycle. So if we consider that that's the root cause of a lot of these problems we've been talking about, we fix that. Number one is get good sleep, get good-quality sleep, and it's not, not just enough time in bed.Lesley Logan 32:02  Yeah, so.Amy Loden Tiffany, MD, MBA 32:03  That's important. Number two is most people don't realize that they're doing it backwards. They're, if they're, if they're even able to get exercise in their life right now, right? So we're going to make the assumption that you figured out some exercise regimen you like. We're, we're at that level, but they're doing it at the wrong time, and they're doing it in a way that they're sabotaging their end result. So rather than going to the gym and then going and eating dinner, or going to the gym first thing in the morning and skipping breakfast and all these things, you need to eat protein and fat, and then you need to move your thighs. I don't care if that's jumping jacks, going for a walk, running up the stairs, something where your thighs are moving regularly for 10 minutes. So make it whatever you like doing. This can be the mom at home who's doing all sorts of fun class activity with her kid, right? Like moving the baby around or the teenager can be equally fun to move around for what it's worth. And then it could be the CEO who's getting ready for a meeting and has 10 minutes after eating whatever lunch she had in the five-minute break she did, right? So looking at what makes sense in your life, but 10 minutes of physical activity, ideally after every meal, that's not realistic, but that's ideal. And then you start with the one meal a day you can do, and you do it most days of the week to start with, because most of us have to figure out how to make it a habit.Lesley Logan 33:15  Yeah.Amy Loden Tiffany, MD, MBA 33:15  But movement for 10 minutes after eating, it's, it's crucial. I cannot stress that enough.Lesley Logan 33:20  I didn't realize it was. It makes total sense moving your body after eating because I like to go for a walk after I have lunch. Otherwise, I'm tired. Correct. I can't go back to work now. Amy Loden Tiffany, MD, MBA 33:30  The reason you're tired though is because your glucose goes up and your insulin went up to match it. When you walk right after you eat, glucose still goes up, but it's less, and so you have less insulin spike. Insulin is the bright driver here, and so you've got to do the movement after. And if it helps to understand why, think back to what our ancestors did 1000 years ago. Right? We weren't checking hormones. We weren't checking insulin. We weren't talking about hacks. We were trying to survive most of the time. Yeah. But the things they did is they, if they, what, after they ate, they moved around. Right? Like they were building their shelters. They were taking care of the kids. They were moving in the community, helping build, create, relocate, whatever. They were always moving, and they did not get the whole three square meals a day. That's bogus. You don't need three meals a day, okay? And most of my ladies don't realize that they're eating their nutrients potentially in the wrong order for their body. That they're eating them in the wrong time for the cycle of the month they're in, they're not getting enough protein, not getting enough fat for their hormones and their brain, and it doesn't happen quickly, right? It's months, years, maybe even a couple decades before they're, I don't know what happened, but my body in the mirror is not the body in my head. This is not who I am. There's a disconnect, and they finally are at that place where they have to do something, where the body is forcing them to stop because they've pushed it as hot as you know.Lesley Logan 34:44  Oh my God, that's a whole episode. We're having you back. I'm just telling you right now because I want to have a whole episode on the whole. Because what I do know is if you eat certain things, if you work out too late, if you get your cortisol up, sleep that. I have been trying to figure out sleep for over a decade, and I, I get good-quality sleep most of the time. But I'm obsessed with it because I'm like, I don't want Alzheimer's. I do not want heart problems. It doesn't really matter what I'm doing at the gym if I'm not sleeping. None of that matters. Doesn't matter what you're, If you don't get good sleep, all the rest is gonna just fall apart anyways. So it's interesting. It makes sense about the food because I remember when I was having problems with my cycle and I had my one of my doctor friends, she said you should try seed cycling because I just, the worst cramps and, like, the worst everything was just the worst in the world, and so I tried seed cycling and my goodness, you know, I'm not a woo-woo girl, but the seed cycling makes, I got, I had no more zits, my boobs didn't hurt as bad, everything leveled out, and I didn't need any extra hormones for it. I was, whoa, so now there must be more. We need to know about it. So we'll have to have you back for that. I can talk to you forever. So we'll just, this is part one of many. I'm just going to take a brief break and then find out if people can find you, follow you, and work with you. All right, Dr. Amy Loden, where do you hang out? You mentioned St. Louis. Can people work with you if they're not in St. Louis? How does this work?Amy Loden Tiffany, MD, MBA 36:03  Yes, absolutely. Best way to get into contact with our office is just going to our website, www.vitalitymwc.org. They can sign up for a consultation, and we can go through what their options are. There is also lots of opportunity if you don't want to work with us directly, but you want to continue the conversation and hear what we're seeing. I do all the social media I can so that people can hear what's being said in their exam rooms and have it in their real lives too. So you can do that on follow me at Dr. Amy Tiffany, whether it's on Instagram or TikTok or Facebook. You find it where they're also on LinkedIn at Dr. Amy Loden. So lots of places depends on what their needs are. One special offer I do have for your audience: we talked about pregnancy and perimenopausal bit through this conversation, they can contact my office for a free physical copy of my book, The Postpartum Pivot. And before you stop listening, ladies, and you think, "Well, I'm not postpartum." If you've had a baby, you're postpartum even it's 20 years ago. Your body's different than it was before that baby, and so you can understand what does this look like for perimenopause and other types of areas that we go through as we grow less young, but grow more wise.Lesley Logan 37:03  Oh my God! Every one of my female females, that's where your Christmas present is. Sorry, just gonna get a doctor because they don't. It's, if their doctor doesn't tell them, they don't know, right? And then they are just going through it. And I feel so bad because every woman in my life is such a badass, and then they get their body doesn't keep up with what they're wanting to do in life, and then it just becomes not just like a liability, but like this hangup. So you are amazing. Okay, you've given us some great stuff already. I mean, we're gonna have to rewind, and I'll listen to this. I've got, you know, getting my notepad out, but our bold, executable, intrinsic, or targeted steps people can take to be it till they see it. What do you have for us?Amy Loden Tiffany, MD, MBA 37:37  I want each one. When you be it as you see it, I want you to be true to what your body's telling you, and recognize nothing's gone wrong. Listen when things are happening and they seem like it's a crisis. Nothing's gone wrong. Your body's talking to you. Listen, and when you listen, you become more wise. You become a better version of yourself.Lesley Logan 37:55  Okay, I really love that. We talked about that earlier, but it's true. Some of us think our body is against us, and it's doing something to us. But really, it's like, hello. The alarm bells. Amy Loden Tiffany, MD, MBA 38:05  It's doing exactly what it should do for the situation we've put it in. That doesn't mean we like it. You get diabetes. No one's like, oh yeah, my body did exactly what it's supposed to do. But if we understand that, then it becomes a neutral thought. It's not bad or wrong. It's I didn't listen, so now I'm going to stop, and the best place to reverse is as soon as you realize you're going in the direction. Right? It's not to keep going in the wrong direction. So nothing has gone wrong. We just need to listen. We need to turn around, create a better story.Lesley Logan 38:33  Love it. Love it. This is and then so enlightening. This is so fun. Thank you so much for being you and your and and the journey that you've been on is something we can all benefit from. So thank you for that, you guys. We all need to share this episode with all the women in our lives, and I would love for you to make sure that Dr. Amy knows your favorite takeaways. Send them to the Be It Pod as well. And since I'm going to have her back, not that I even like asked her beforehand, but I'm just going to tell her she's doing that. You can send your questions, and we'll make sure we get that. So, beitpod.com/questions. Until next time, my loves, Be It Till You See It. Lesley Logan 39:03  That's all I got for this episode of the Be It Till You See It Podcast. One thing that would help both myself and future listeners is for you to rate the show and leave a review and follow or subscribe for free wherever you listen to your podcast. Also, make sure to introduce yourself over at the Be It Pod on Instagram. I would love to know more about you. Share this episode with whoever you think needs to hear it. Help us and others Be It Till You See It. Have an awesome day. Be It Till You See It is a production of The Bloom Podcast Network. If you want to leave us a message or a question that we might read on another episode, you can text us at +1-310-905-5534 or send a DM on Instagram @BeItPod.Brad Crowell 39:45  It's written, filmed, and recorded by your host, Lesley Logan, and me, Brad Crowell.Lesley Logan 39:50  It is transcribed, produced and edited by the epic team at Disenyo.co.Brad Crowell 39:54  Our theme music is by Ali at Apex Production Music and our branding by designer and artist, Gianfranco Cioffi.Lesley Logan 40:02  Special thanks to Melissa Solomon for creating our visuals.Brad Crowell 40:05  Also to Angelina Herico for adding all of our content to our website. And finally to Meridith Root for keeping us all on point and on time.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Taking the risk no one else will: how Medical 21 is working to replace harvested blood vessels with an artificial coronary artery that becomes part of the patient's own body. In this episode, Manny Villafana, Founder and CEO of Medical 21, returns to discuss his team's progress in developing an artificial coronary artery for bypass surgery. Drawing on more than five decades of medical device innovation, he reflects on how his earlier companies helped create longer-lasting pacemakers and lifelong heart valves that transformed cardiovascular care. Manny explains how Medical 21's graft is designed to grow into a living blood vessel made from the patient's own cells, potentially eliminating the need to harvest vessels during bypass surgery and reducing pain, recovery time, infection risk, and costs. He also shares updates on the company's preclinical progress, partnership with the Mayo Clinic, fundraising efforts, and why pursuing seemingly impossible ideas is essential to advancing medicine. Tune in to learn how bold thinking, regenerative technology, and a willingness to take risks could reshape coronary bypass surgery! Resources: Connect with and follow Manny Villafana on LinkedIn. Follow Medical 21 on LinkedIn and explore their website!

Cardiovascular disease remains the number one killer of both women and men in the United States. Most of us will need to see a cardiologist or cardiac surgeon at some point in our lives. But, how do you find the best doctor who is right for you? In this episode, three experts representing different subspecialties within cardiovascular health offer advice to patients asking: How do I pick a cardiologist or cardiac surgeon? Jeffrey Kuvin, MD, is executive director and senior vice president of cardiology at Northwell Health. He is also co-executive director of the Northwell Cardiovascular Institute. Alan Hartman, MD, is senior vice president and executive director of cardiovascular and thoracic surgery at Northwell Health. He is also chair of cardiovascular and thoracic surgery at North Shore University Hospital and Long Island Jewish Medical Center. Varinder Singh, MD, is senior vice president of cardiology for Northwell's Metro Market and the Guenther Chair for the Department of Cardiology at Lenox Hill Hospital. Chapters: 00:01 - Intro 01:09 - Who should see a cardiologist? 02:19 - Start with your primary care doctor 03:01 - Is the doctor Able? Affable? Available? 03:29 - Connecting with your doctor 05:38 - Finding the right cardiac surgeon 07:18 - Quality ratings 09:45 - The importance of trust 12:!7 - General vs interventional cardiology 14:14 - What is your vascular age? 15:44 - Why volume matters 17:00 - Does gender play a factor Further references: Learn more about quality ratings for cardiac surgery NYS Department of Health (DOH) 2026 report on adult cardiac surgery US News & World Report rankings Society of Thoracic Surgeons reports Northwell Cardiovascular Institute 2025 Annual Report Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

Join guest Morgan Lewis, an Amyloid Nurse Clinician, to learn about how ATTR-CM impacts patient's quality of lives. Morgan describes the variants of ATTR-CM as well ad dives into the ongoing unmet needs of patients iwth ATTR-CM. Morgan shares practical examples to overcome challenges to patient care and optimal health outcomes using team-based care strategies.Related PCNA Resources:The Role of Artificial Intelligence in Cardiovascular Care: ATTR Case Study (CE Course)Heart Failure and ATTR-CM: A Guide for Health Care ProfessionalsHereditary Amyloidosis: What you need to know fact sheetSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Join guest Dana Miller, Advanced HF Nurse Practitioner, to discuss the science and evidence to turn the tide on ATTR. Dana provides an overview of recent clinical trials and how an ATTR-CM diagnosis impacts rate of hospitalization, mortality and quality of life. Dana shares resources and recommendations to continue to learn more about the ever-evolving ATTR-CM treatment and management strategies.Related PCNA Resources:The Role of Artificial Intelligence in Cardiovascular Care: ATTR Case Study (CE Course) Heart Failure and ATTR-CM: A Guide for Health Care Professionals Hereditary Amyloidosis: What you need to know fact sheet Related Episode Resources:CRISPR-Cas9 In Vivo Gene Editing for Transthyretin AmyloidosisTransthyretin Cardiac Amyloidosis Evaluation and Management: 2025 ACC Concise Clinical GuidanceChanging Patterns of Diagnosis and Survival in Transthyretin Cardiac Amyloidosis: A Multicenter Cohort StudyOutcomes in patients with cardiac amyloidosis undergoing catheter ablation for atrial arrhythmiasAmyloidosis Research ConsortiumHeart Failure Society of America (HFSA)See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Join guest Emily Brown, a Cardiovascular Genetic Counselor who has worked with ATTR-CM patients for over a decade. Emily dives into the role of genetic testing in diagnostics and personalized therapies. Emily shares practical strategies and examples of team based care with a multi-disciplinary care team to tackle turning the tide on ATTR-CM. Emily shares suggestions for resources and support for genetic testing for patients.Related PCNA Resources:The Role of Artificial Intelligence in Cardiovascular Care: ATTR Case Study (CE Course) Heart Failure and ATTR-CM: A Guide for Health Care Professionals Hereditary Amyloidosis: What you need to know fact sheet Related Episode Resources:ForgingBridges - Resources to help support you and your patients See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Las enfermedades cardiovasculares pueden estar relacionadas con distintos factores de riesgo que, en algunos casos, pueden prevenirse o controlarse. En este episodio de Actitud Saludable, el Dr. Crisanto Aaron Amaro Gutiérrez, Cardiólogo Clínico de Hospital Galenia, nos habla sobre los principales factores que pueden afectar la salud cardiovascular y las nuevas terapias disponibles para fortalecer su prevención. Descubre cómo una evaluación oportuna y un manejo adecuado pueden ayudar a reducir riesgos y proteger la salud de tu corazón.El Dr. Crisanto Aaron Amaro Gutiérrez te invita a escuchar el #podcast para conocer más del tema. ¡No te pierdas sus recomendaciones! ¡Disfruta del episodio 330 y continúa escuchando cada uno de nuestros #PodcastsMédicos  preparados especialmente para ti!➡️ ENLACES DE INTERÉS

Contributor: Aaron Lessen, MD Educational Pearls:  Blunt cerebrovascular injury (BCVI) BCVI is a traumatic injury to the carotid or vertebral arteries Patients may initially have no neurologic symptoms In some cases, a thrombus can form at the site of the injury and later cause ischemic stroke, sometimes hours after the original trauma CT angiography (CTA) of the neck is a useful screening tool for BCVI HIstorically, CTA was reserved for patients with high-risk mechanisms or neurologic symptoms CTA screening has expanded as understanding of BCVIs and their prevention progresses The Denver criteria were developed to identify patients with increased risk for BCVI High-risk findings include cervical spine injuries and severe facial or skull-base fractures Screening practices still vary between trauma centers, though expansion of proactive CTA is an increasingly common practice   References Kim DY, et al. Evaluation and management of blunt cerebrovascular injury: A practice management guideline from the Eastern Association for the Surgery of Trauma. J Trauma Acute Care Surg. 2020. Biffl WL, et al. Screening for and treatment of blunt cerebrovascular injuries: Western Trauma Association critical decisions algorithm. J Trauma. 2009. Brommeland T, et al. Best practice guidelines for blunt cerebrovascular injury. Scand J Trauma Resusc Emerg Med. 2018. Harper PR, et al. Routine CTA screening identifies blunt cerebrovascular injuries missed by clinical risk factors. Trauma Surg Acute Care Open. 2022.   Summarized by Sam Pahl | Edited by Sam Pahl & Ahmed Abdel-Hafiz, NREMT-P   Donate: https://emergencymedicalminute.org/donate/   Join our mailing list: http://eepurl.com/c9ouHf  

Cardiovascular-Kidney-Metabolic (CKM) syndrome recognizes the interconnected relationship among cardiovascular disease, kidney disease, obesity, diabetes, and other metabolic risk factors that contribute to long-term health outcomes. The first-ever CKM clinical practice guideline introduces a framework for risk assessment, staging, prevention, and management, emphasizing early identification and coordinated care across disease states. You will be better prepared to recognize CKM syndrome, understand its implications for patient care, and support evidence-based strategies to reduce cardiovascular, kidney, and metabolic risk. HOSTRachel Maynard, PharmDGameChangers Podcast Host and Lead, Clinical & Partnership Education, CEimpactGUESTChristine Schumacher, PharmD, BCPS, BCACP, BCCP, BC-ADM, CDCES, FCCPProfessor, Pharmacy Practice and Clinical PharmacistMidwestern University Pharmacists, REDEEM YOUR CPE HERE!CPE is available to Health Mart franchise members onlyTo learn more about Health Mart, click here: https://join.healthmart.com/PRACTICE RESOURCEReceive the exclusive Practice Resource to use as a reference guide for this episode by enrolling in the course. Click here to enroll!CPE INFORMATION Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Describe the stages and key components of cardiovascular-kidney-metabolic syndrome.2. Explain evidence-based strategies for identifying and managing patients at risk for CKM syndrome.Christine Schumacher is a Speaker and Advisory Board Member for Abbott. All relevant financial relationships have been mitigated. 0.075 CEU/0.75 HrUAN: 0107-0000-26-315-H01-PInitial release date: 8/31/2026Expiration date: 8/31/2029Additional CPE details can be found here.

Cardiovascular-Kidney-Metabolic (CKM) syndrome recognizes the interconnected relationship among cardiovascular disease, kidney disease, obesity, diabetes, and other metabolic risk factors that contribute to long-term health outcomes. The first-ever CKM clinical practice guideline introduces a framework for risk assessment, staging, prevention, and management, emphasizing early identification and coordinated care across disease states. You will be better prepared to recognize CKM syndrome, understand its implications for patient care, and support evidence-based strategies to reduce cardiovascular, kidney, and metabolic risk.HOSTRachel Maynard, PharmDGameChangers Podcast Host and Lead, Clinical & Partnership Education, CEimpactGUESTChristine Schumacher, PharmD, BCPS, BCACP, BCCP, BC-ADM, CDCES, FCCPProfessor, Pharmacy Practice and Clinical PharmacistMidwestern UniversityGET CE FOR LISTENING!Stay Compliant. Grow Clinically. Practice with Confidence. Pharmacist CE Subscription: All your CE in one convenient subscription.All episodes, CE, and Practice Resources for the GameChangers Clinical Update is included with your Pharmacist CE Subscription. But wait…there's even more!The Pharmacist CE Subscription includes: -  Compliance and licensure CE -  GameChangers Clinical Updates-  Practical continuing education across patient care topics *The subscription does not include microcredentials or certificates, which are available separately for pharmacists seeking specialized service training. Purchase Now!PRACTICE RESOURCEReceive the exclusive Practice Resource to use as a reference guide for this episode by purchasing the Pharmacist CE Subscription. CPE REDEMPTIONThis course is accredited for continuing pharmacy education! Click the link below that applies to you to take the exam and evaluation to claim credit:If you are already enrolled in this course, click here to redeem your credit. To purchase the Pharmacist CE Subscription and claim your CPE credit, click here or to purchase this course individually, click here.  CPE INFORMATIONLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Describe the stages and key components of cardiovascular-kidney-metabolic syndrome.2. Explain evidence-based strategies for identifying and managing patients at risk for CKM syndrome.Christine Schumacher is a Speaker and Advisory Board Member for Abbott. All relevant financial relationships have been mitigated.  0.075 CEU/0.75 HrUAN: 0107-0000-26-315-H01-PInitial release date: 8/31/2026Expiration date: 8/31/2029Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

Como as novas diretrizes da Sociedade Europeia de Cardiologia, a autocoleta domiciliar no rastreamento cervical e o enfrentamento de surtos infecciosos transformam o cuidado em saúde? Neste episódio do Afya News, analisamos a primeira diretriz da ESC totalmente dedicada à reabilitação cardiovascular, estabelecendo-a como intervenção multidisciplinar precoce para diversas condições, incluindo a cardio-oncologia. Discutimos também a expansão do programa do NHS na Inglaterra com kits de autocoleta de HPV entregues em domicílio para superar barreiras de acesso e diagnosticar o câncer cervical precocemente. Por fim, apresentamos no Radar a gravidade epidemiológica do surto de Ebola na República Democrática do Congo, que já registra milhares de óbitos e reforça a urgência de medidas de biossegurança. O Afya News apresenta notícias da medicina com informação confiável e atualizada no seu tempo. Criado pela Afya, o maior hub de educação e soluções para a prática médica do Brasil, nosso propósito é transformar a saúde junto com quem tem a medicina como vocação.Fontes do episódio aqui:⁠https://portal.afya.com.br/podcasts/afya-news/31-08-2026 Conteúdo 100% validado por equipe médica.Médico Responsável: Dr. Guilherme Rodrigues — CRM-RJ 1049461.

Why does your heart rate keep climbing during a long hike even though you're walking at the same pace—or even slowing down?This phenomenon is called cardiovascular drift, and it is an important physiologic response to prolonged exercise. In this podcast, we explore what happens to the heart during a long hike as dehydration, heat, altitude, and fatigue begin to affect the cardiovascular system.The heart is a pump—but the pump has to fill before it can pump. Understanding venous return will help you become a safer and more knowledgeable wilderness traveler.

This week we review the use of right axillary artery access for aortic valvuloplasty in infants. Why would this approach potentially offer advantages versus the more traditional femoral or even carotid approach? What are the particular dangers of this approach? How should the interventionist pick the approach when planning an aortic valvuloplasty in an infant with valvar aortic stenosis? We speak with Dr. Jameel Al-Ata of King Faisal Specialist Hospital in Jeddah, Saudi Arabia this week. DOI: 10.1007/s00246-025-03991-6

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Cardiovascular Care Should Incorporate Cognition and Frailty, Heart Group Says in New Statement." Related Content: Cardiovascular Care Should Incorporate Cognition and Frailty, Heart Group Says in New Statement

Cardiovascular disease remains a leading and preventable contributor to maternal death, and women with the highest-risk heart conditions can face maternal morbidity rates approaching 50%. In this vodcast, learn how to support patients with preexisting heart disease through every stage of the reproductive journey, from preconception counseling to postpartum care. This session highlights risk stratification, collaborative care planning, and evidence-based strategies to improve maternal and fetal health outcomes.   For more professional resources on maternal health, please visit professional.heart.org/maternal-health. 

What if one of the most powerful tools for improving your cardiovascular resilience was already built into your body—and completely free? In this science-forward solo episode, Darin dives into the fascinating physiology of breath holding and the mammalian dive response, an ancient survival mechanism humans share with seals, whales, and dolphins. Simply holding your breath triggers an extraordinary cascade inside the body: your heart rate slows, blood vessels constrict to preserve oxygen for vital organs, and your spleen contracts to release oxygen-rich red blood cells into circulation. Darin explores research on elite freedivers, Southeast Asian sea nomads, cardiac hypoxic resistance, and the remarkable ways the human body can adapt to repeated breath-hold training. But he also separates the evidence from the hype, explaining why breath holding alone isn't a miracle intervention and why some of the most promising benefits appear when hypoxic stress is combined with movement and resistance exercise. This episode is a reminder that some of the most extraordinary tools for improving human performance aren't expensive supplements or complicated technologies—they're capacities your body has possessed all along. What You'll Learn What happens inside your body the moment you hold your breath How the mammalian dive response slows your heart rate and redirects blood flow Why your spleen acts like a biological reservoir for oxygen-rich red blood cells How humans share this ancient survival mechanism with marine mammals Why Southeast Asian sea nomads developed remarkable adaptations for freediving How breath-hold training can amplify the body's natural dive response What researchers discovered when elite divers reached extraordinarily low blood oxygen levels How repeated training may create greater hypoxic resilience in the heart Why the long-term benefits of breath-hold training in everyday people are still being studied Why combining hypoxic stress with movement may be more powerful than breath holding alone Chapters 00:00:03 – Welcome to SuperLife 00:00:34 – Sponsor: Alkemis 00:03:26 – The incredible thing happening when you hold your breath 00:03:57 – The ancient survival program you share with dolphins and whales 00:04:31 – The hidden cardiovascular tool almost nobody trains 00:05:03 – A free physiological capacity already built into your body 00:05:38 – What the science actually says about breath-hold training 00:06:09 – Understanding the mammalian dive response 00:06:37 – Your heart, blood vessels, and spleen react within seconds 00:07:11 – Your spleen is a biological oxygen reservoir 00:08:05 – Sponsor: Manna Vitality 00:09:59 – Why cold water amplifies the dive response 00:10:07 – The extraordinary physiology of Southeast Asian sea nomads 00:10:39 – Humans performing underwater like marine mammals 00:11:14 – The mammalian dive response is trainable 00:11:54 – What happened when elite divers reached extremely low blood oxygen 00:12:30 – How the heart adapts during extreme breath holds 00:13:08 – Cardiac hypoxic resistance and a stronger trained heart 00:13:55 – The important limitations of the current research 00:14:41 – Why breath holding alone isn't a miracle 00:15:09 – Combining hypoxic stress with resistance exercise 00:15:42 – Breath holding as a multiplier, not a replacement 00:16:33 – Practical takeaways for training the dive response 00:17:48 – Final thoughts and closing Thank You to Our Sponsors Alkemis: Go to https://alkemispaint.com/ and use code DARIN10 for 10% off your order. Manna Vitality: Go to mannavitality.com/ and use code DARIN12 for 12% off your order. Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only $7.49/month at https://patreon.com/darinolien Find More from Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness Key Takeaway "You already have an ancient cardiovascular survival mechanism built into your body. Breath holding can trigger measurable changes in heart rate, blood flow, oxygen availability, and the body's response to hypoxic stress—and with training, that response appears capable of adapting. The goal isn't to treat breath holding like a miracle hack. It's to recognize it as another powerful physiological tool that may become even more effective when intelligently combined with movement and training. Bibliography/Sources Hypoxic Training & Cardiovascular Adaptation Bosco, G., et al. (2021). Effect of apnea-induced hypoxia on cardiovascular adaptation and circulating biomarkers of oxidative stress in elite breath-hold divers. Frontiers in Physiology . https://pmc.ncbi.nlm.nih.gov/articles/PMC8458773/ Combined training in hypoxic environments improves cardiometabolic health in older adults: A systematic review and meta-analysis of randomized controlled trials. (2025). Frontiers in Medicine . https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1728637/full Costalat, G., et al. (2021). Physiology, pathophysiology and (mal)adaptations to chronic apnoeic training: A state-of-the-art review. European Journal of Applied Physiology, 121, 2669–2685 . https://link.springer.com/article/10.1007/s00421-021-04664-x Palada, I., Bakovic, D., Valic, Z., et al. (2007). Cardiovascular regulation during apnea in elite divers. Hypertension, 50(2) . https://www.ahajournals.org/doi/10.1161/hypertensionaha.108.127530 Patrizio, I., et al. (2021). Cardiac hypoxic resistance and decreasing lactate during maximum apnea in elite breath-hold divers. Scientific Reports, 11, 3676 . https://www.nature.com/articles/s41598-021-81797-1 The Mammalian Dive Reflex & Genetic Adaptations Ilardo, M. A., Moltke, I., Korneliussen, T. S., et al. (2018). Physiological and genetic adaptations to diving in sea nomads. Cell, 173(3), 569–580 . https://news.berkeley.edu/2018/04/19/enlarged-spleen-key-to-diving-endurance-of-sea-nomads/ Schagatay, E. (2000). Studies on trained apnea divers' amplification of the diving response. Mid Sweden University . https://freedivecafe.com/2019/06/04/42-transcript-erika-schagatay-the-science-of-freediving/ Speck, D. F., & Bruce, D. S. (1978). Effects of varying thermal and apneic conditions on the human diving reflex. Undersea Biomedical Research . https://www.scientificamerican.com/article/breath-holding-dive-reflex-extends/ Inspiratory Muscle Strength Training (IMST) Craighead, D. H., Heinbockel, T. C., Freeberg, K. A., et al. (2021). Time-efficient inspiratory muscle strength training lowers blood pressure and improves endothelial function, NO bioavailability, and oxidative stress in midlife/older adults with above-normal blood pressure. Journal of the American Heart Association, 10(13) . https://www.ahajournals.org/doi/10.1161/JAHA.121.022203

In this episode of the Psychedelic Medicine Podcast, Fernando Rivas, MD, joins to unpack the safety and screening considerations for ibogaine therapy. Dr. Rivas is an emergency physician with over 15 years of clinical experience. As Chief Medical Officer of Transcend Clinic, he has led the development of innovative treatment protocols in addiction medicine and the clinical application of ibogaine. In this conversation, Dr. Rivas discusses who may be a good candidate for ibogaine therapy and the clinical considerations involved in determining its safety. He explains that ibogaine has the strongest current support for interrupting substance use disorders and addressing TBI and PTSD, while potential applications in other areas remain emerging and require further research. Throughout the conversation, Dr. Rivas emphasizes the importance of distinguishing absolute from relative contraindications and of carefully screening patients for psychiatric risks, cardiac conditions, and medication interactions. He also discusses medically supported detox protocols, the importance of evaluating treatment through an individualized risk-benefit framework, and how lower-dose or non-psychedelic approaches may eventually broaden access to ibogaine's potential neuroplastic effects.   In this episode, you'll hear: What conditions ibogaine has been most studied for and where its potential applications may be expanding The psychiatric and physical conditions that may make someone an unsuitable candidate for ibogaine treatment How patients with active opioid or alcohol use may be medically supported and stabilized before treatment Why relative contraindications should be evaluated through an individualized risk-benefit analysis How ibogaine's typical psychedelic experience may be shorter than its reputation suggests Why the immediate improvements some patients experience should be understood within the broader context of neuroplasticity and long-term integration   Quotes: "Ibogaine is the most robust of the [psycho]plastogens in terms of the window of time that it is able to open [for increased neuroplasticity]—at least as per preclinical research. So the potential is tremendous." [3:22] "Cardiovascular health is the most important [safety consideration for ibogaine therapy]. If you have a big hypertrophic heart and a large dilated heart, the risks are greater. If you have rhythm disturbances, the risks are greater and sometimes unacceptable." [11:08] "The chances [of an adverse cardiac event] are mitigated by properly screening and vetting patients, as well as by the addition of magnesium to ibogaine treatment. Magnesium is an essential component, as it is cardioprotective. … It simply raises the threshold for an irregular heartbeat or to occur."  [17:38] "A first degree relative with schizophrenia, for example, would be a relative contraindication. However, we must think of this in terms of risk and benefit. If this person is injecting fentanyl every day, they are at risk of overdose and death every single day. … so that relative contraindication should always be ascertained in terms of risk-benefit, particularly risk to life when it is present." [29:31] "The science currently supports that sufficient exposure over a short enough period of time can yield pretty much the same results in terms of [neuro]plasticity without incurring a psychedelic experience. And we have tailored some specific treatments for patients that did not wish to incur a psychedelic experience, yet wanted to obtain the benefits of the plastic component of ibogaine treatment." [32:15]   Links: Dr. Rivas on Instagram Transcend Clinic website Previous episode: Psychedelics and Psychosis with Alexander Lebedev, MD, PhD Psychedelic Medicine Association Porangui

Running is one of the most accessible forms of exercise, offering benefits that extend far beyond cardiovascular fitness. In this episode of Health Matters, host Courtney Allison speaks with Dr. Morgan Busko, a sports medicine physician at NewYork-Presbyterian and Columbia and a competitive triathlete, about the physical and mental rewards of running. Dr. Busko explains why strength training is a critical foundation for runners and discusses how exercises that target the core and gluteal muscles can improve stability and help prevent injuries. She also breaks down the differences between dynamic warmups and static stretching, explaining how proper preparation can support healthier training. The conversation covers practical strategies for runners at every level, from walk-run programs for beginners to training plans for race day. Dr. Busko shares advice on gradually increasing mileage, building endurance safely, and avoiding common training mistakes that can lead to injury. Finally, she discusses the important roles sleep, nutrition, hydration, and recovery play in athletic performance, debunks the myth that running causes arthritis, and offers encouragement for anyone looking to start or return to running. Chapters 00:00 – Why Running Is Good for Body and Mind The physical and mental health benefits of running and why runners keep coming back 03:00 – Getting Started and Building Strength How to return to running after a break, why strength training matters, and exercises that help prevent injuries 06:20 – Training Smarter and Avoiding Injury Dynamic warmups, walk-run programs, race preparation, and common training mistakes 10:00 – Recovery, Fueling, and Running for the Long Term Sleep, nutrition, hydration, injury warning signs, and the myth that running causes arthritis – and tips to enjoy the sport Key Topics Covered Running Running for beginners Sports medicine Running and mental health Cardiovascular health Strength training for runners Injury prevention Core strength Glute strength Dynamic warmups Static stretching Race training Marathon training 5K training Walk-run method Running recovery Sleep and athletic performance Sports nutrition Hydration for runners Energy gels Running motivation Running injuries Arthritis and running Sports performance Healthy exercise habits Key Takeaway Running can improve cardiovascular health, strengthen the body, reduce stress, and support overall well-being, but success starts with a thoughtful approach. Building strength, progressing gradually, prioritizing recovery, and listening to your body can help prevent injuries and make running a sustainable, rewarding part of a healthy lifestyle. Doctor Bio Morgan Busko, MD is a sports medicine physician at NewYork-Presbyterian and Columbia specializing in the non-operative treatment of chronic and acute musculoskeletal injuries and conditions in adult and pediatric patients. She has a particular interest in endurance athletes, running and overuse injuries, and injury prevention. After completing a residency in Internal Medicine at New York University, where she also received her Medical Degree, Dr. Busko completed a Sports Medicine Fellowship at Wake Forest University. She received her B.S. in Biological Anthropology and Anatomy at Duke University, where she competed in Cross-Country and Track & Field. Dr. Busko is an active endurance athlete who has competed in the Hawaii Ironman World Championship five times, finishing amongst the top triathletes in the world. She finds great reward in helping athletes return to sport safely while facilitating an athlete's ability to reach their optimal athletic performance. She hopes that her passion for exercise as medicine will be contagious to her patients and everyone around her.

Focus Issue on Cardiovascular genetics - from mechanisms to clinical applications

In this MedAxiom HeartTalk, host Melanie Lawson, MS, talks with Jacob Corbell, MBA, CEO of Midwest Cardiovascular Institute, about the administrative strain pulling time away from patient care. Corbell shares how partnering with Basata helped his team cut call abandonment to 1% and reduce hold times to under 30 seconds. He also explains why the real opportunity is not replacing staff but freeing them to do more meaningful work. It's a practical look at where AI is already making a difference and where it could go next.

This week I'm joined by Dr Jack Kreindler, physician, healthtech entrepreneur and founder of WellFounded Health and the Centre for Health and Human Performance, and someone who has spent 26 years asking one of the most important questions in medicine, what does it mean to not just fix disease, but to truly enhance human life?We explore longevity, prevention, performance and what the most advanced medicine in the world is learning about how to live well for longer.Dr Jack Kreindler qualified in medicine and physiology from University College London and spent a decade as an emergency physician before founding the Centre for Health and Human Performance in Harley Street in 2007. He is an honorary clinical research fellow at Imperial College London, founder and CEO of WellFounded Health and a leading voice on healthy longevity, human performance and the future of medicine. He has worked with elite athletes, extreme environment explorers and high performance executives across the world.What we explore together:Why medicine is shifting from fixing disease to enhancing physiology and what that means for youWhat burning the candle at three ends is actually doing to your brain and bodyWhy cadence is king and how everything in nature and biology moves in wavesWhat the most advanced health testing actually looks like and what it tells usThe truth about longevity supplements, peptides and biohacking and who they actually work forWhy your history is still the most powerful diagnostic tool ever inventedWhat it really means to enhance a human life rather than just extend itLove, Sarah Ann

Mundo Salud - Dieta y salud cardiovascular, Esteban Ortiz y Óscar Ojeda by FM Mundo 98.1

Sophie Cunningham lit the internet on fire when she said we need to protect the safety of girls and the integrity of women's sports, and the conversation quickly turned into another political battleground even though the underlying question is really about biology, anatomy, and physiology. Inside today's episode, I break down what the research says about testosterone suppression, puberty, and the physiological differences between men and women that don't disappear just because testosterone levels come down. Topics discussed: - A Brief History of Trans Athletes in Sport- Pre-Puberty Differences Between Boys and Girls- What Male Puberty Does That Can't Be Reversed- What Testosterone Suppression Does and Doesn't Change- Bone Density, Muscle Mass, and Neural Capacity- Spironolactone, Oral Estradiol, and Half-Life Windows- The NCAA Rule Change of February 2025- Why the Biology Deserves an Honest Look---------- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.metabolismschool.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- [Free] Metabolism School 101: The Video Series⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.metabolismschool.com/metabolism-101⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------Subscribe to My Youtube Channel: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grab a Copy of My New Book - Metabolism Made Simple⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- Stay Connected: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube: SamMillerScience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook: The Nutrition Coaching Collaborative Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠operations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@sammillerscience.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."

Cardiovascular disease remains a leading cause of death, while evolving guidelines and increasingly aggressive LDL cholesterol targets are changing how clinicians approach lipid management. Jodi Martinez, Pharmacist Clinical Specialist in Cardiology at the University of Colorado Hospital, part of UCHealth, joins Kerry Schwarz, Senior Clinical Manager for Evidence Based Medicine and Outcomes with the Vizient Center for Pharmacy Practice Excellence, to explore the emerging role of enlicitide in lipid management. They discuss the evidence behind its approval, its potential to expand patient access and where this first oral PCSK9 inhibitor may fit alongside existing therapies.   Guest Speaker: Dr. Jodi Martinez, Pharm.D., BCPS, BCCP, HF-CERT Pharmacist Clinical Specialist in Cardiology University of Colorado Hospital, UCHealth   Host:  Dr. Kerry Schwarz, Pharm.D., MPH Senior Clinical Manager, Evidence-Based Medicine and Outcomes Vizient Center for Pharmacy Practice Excellence    Show Notes:  [01:26] The limitations of current lipid management and why many high-risk patients still struggle to reach increasingly aggressive LDL cholesterol targets. How cost, prior authorization requirements and step therapy can create barriers to accessing injectable PCSK9 therapies. [03:27] The evidence behind enlicitide and findings from the CORALreef clinical trial supporting its FDA approval. How enlicitide performed across LDL cholesterol, non-HDL cholesterol, ApoB and lipoprotein(a) endpoints, and why cardiovascular outcomes remain an important unanswered question. [06:37] An oral PCSK9 inhibitor could expand access by offering an alternative to specialty injectable therapies. Why retail pharmacy availability, cost and greater prescribing flexibility could help more patients receive intensive lipid lowering therapy. [08:11] The potential barriers to enlicitide adoption, including delays in formulary review, insurance coverage and the administrative burden placed on clinicians. The lack of published cardiovascular outcomes could influence payer coverage, formulary placement and early uptake. [10:15] Station remains the cornerstone of lipid management and where enlicitide may ultimately play a role Clinicians may consider the amount of LDL reduction a patient needs when choosing among available therapies.   Links and Resources: 2022 ACC Expert Consensus Decision Pathway on the Role of Nonstatin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk: A Report of the American College of Cardiology Solution Set Oversight Committee 2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines   Subscribe Today! Apple Podcasts Spotify YouTube RSS Feed    

Cardiovascular disease is a major threat to maternal health during pregnancy and the peripartum period, particularly for women with preexisting heart conditions. A UC San Diego cardiologist describes the development of a multidisciplinary cardio-obstetrics initiative designed to coordinate care for patients with congenital heart disease, heart failure, arrhythmias and coronary artery disease. The program brings cardiology and maternal-fetal medicine together with other specialties to establish consistent protocols, improve maternal and fetal outcomes, advance research and train future clinicians. As more people born with congenital heart disease survive into adulthood and consider pregnancy, the need for this specialized care continues to grow. Longitudinal surveillance is also helping researchers study outcomes and identify opportunities for better monitoring. Coordinated cardio-obstetrics care can help manage complex cardiovascular risks throughout pregnancy and delivery. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41641]

Cardiovascular disease is a major threat to maternal health during pregnancy and the peripartum period, particularly for women with preexisting heart conditions. A UC San Diego cardiologist describes the development of a multidisciplinary cardio-obstetrics initiative designed to coordinate care for patients with congenital heart disease, heart failure, arrhythmias and coronary artery disease. The program brings cardiology and maternal-fetal medicine together with other specialties to establish consistent protocols, improve maternal and fetal outcomes, advance research and train future clinicians. As more people born with congenital heart disease survive into adulthood and consider pregnancy, the need for this specialized care continues to grow. Longitudinal surveillance is also helping researchers study outcomes and identify opportunities for better monitoring. Coordinated cardio-obstetrics care can help manage complex cardiovascular risks throughout pregnancy and delivery. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41641]

Cardiovascular disease is a major threat to maternal health during pregnancy and the peripartum period, particularly for women with preexisting heart conditions. A UC San Diego cardiologist describes the development of a multidisciplinary cardio-obstetrics initiative designed to coordinate care for patients with congenital heart disease, heart failure, arrhythmias and coronary artery disease. The program brings cardiology and maternal-fetal medicine together with other specialties to establish consistent protocols, improve maternal and fetal outcomes, advance research and train future clinicians. As more people born with congenital heart disease survive into adulthood and consider pregnancy, the need for this specialized care continues to grow. Longitudinal surveillance is also helping researchers study outcomes and identify opportunities for better monitoring. Coordinated cardio-obstetrics care can help manage complex cardiovascular risks throughout pregnancy and delivery. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41641]

Cardiovascular disease is a major threat to maternal health during pregnancy and the peripartum period, particularly for women with preexisting heart conditions. A UC San Diego cardiologist describes the development of a multidisciplinary cardio-obstetrics initiative designed to coordinate care for patients with congenital heart disease, heart failure, arrhythmias and coronary artery disease. The program brings cardiology and maternal-fetal medicine together with other specialties to establish consistent protocols, improve maternal and fetal outcomes, advance research and train future clinicians. As more people born with congenital heart disease survive into adulthood and consider pregnancy, the need for this specialized care continues to grow. Longitudinal surveillance is also helping researchers study outcomes and identify opportunities for better monitoring. Coordinated cardio-obstetrics care can help manage complex cardiovascular risks throughout pregnancy and delivery. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41641]

In this episode, Mark J. Ricciardi, MD, Section Chief Interventional Cardiology and Structural Heart; Charles Walgreen Jr Chair, Endeavor Health (formerly NorthShore) Cardiovascular Institute; Clinical Prof University of Chicago Pritzker School of Medicine, discusses cardiovascular innovation, minimally invasive valve therapies, clinical trials and the importance of building a culture that prioritizes research alongside clinical care.

This week we speak with Ms. Sharon Welsh BSN, RN about a novel project she has embarked upon called CLEAR CHD PHYSIOLOGY (on Instagram chdphysiology.icu) which is a physiology-based site intended to teach bedside critical care nurses about CHD physiology. What signs or symptoms are important and what is their meaning? Why is nursing at the bedside of a sick postoperative newborn so much more difficult than it was at the start of Ms. Welsh's career? How does Ms. Welsh use AI to create a flexible learning tool for RN's and all interested in congenital heart physiology? Ms. Welsh provides the answers this week. 

In this episode of the Fit Father Project Podcast, I make the case for the single most powerful longevity lever in exercise science: Cardiovascular training.Pulling from major studies out of the Cleveland Clinic, the VA, and Copenhagen, I explain why VO2 max — your body's ability to take in and use oxygen — is a stronger predictor of how long you'll live than your weight, cholesterol, or even your muscle mass.I state this clearly: This isn't an argument against lifting. Strength training is non-negotiable for your bones, blood sugar, and independence as you age. But I break down the research showing that muscle alone doesn't train your mitochondria — the power plants inside every cell — the way cardiovascular work does.I walk you through exactly how much cardio you actually need, the different types (zone two, intervals, all-out sprints), and how to fit all of it around the strength training you're already doing inside the Fit Father programs.If you've been all-in on lifting and protein but ignoring your heart and lungs, this episode will change how you think about your training for the rest of your life.Rate & Review — If this episode changed how you think about your training, please take a moment to rate and review the Fit Father Project Podcast. Your review helps more men over 40 find the show and the tools they need to build strength, energy, and long-term health.Join the Fit Father Community — If you want help putting this into action with real accountability, join us inside the Fit Father Project. We'll help you build a training plan that covers strength, cardio, and everything in between — built specifically for busy dads over 40.Key TakeawaysVO2 max — the maximum oxygen your body can take in and use — is the strongest predictor of longevity ever measured, ahead of weight, cholesterol, or muscle massCleveland Clinic study (122,000 adults, 8.4-year follow-up): the fitter you were, the longer you lived, with no ceiling — the fittest people lived the longestVA study of 750,000 veterans: every 1 MET increase in fitness meant a 13-15% drop in death risk, regardless of age, weight, sex, or existing diseaseCopenhagen study (46-year follow-up): each 1-unit increase in VO2 max was linked to roughly 45 extra days of lifeVO2 max naturally declines about 10% per decade after age 30 — cardio training is one of the best ways to slow that declineMayo Clinic study: strength training alone improved lean mass and blood sugar, but only cardio and combined groups improved aerobic capacity and mitochondrial functionAdults age 65-80 saw even bigger mitochondrial gains (69%) than younger adults (49%) from cardio intervals — it's never too late to startWalking is valuable, but mortality benefits plateau around 6,000-8,000 steps a day — steps alone won't create the mitochondrial adaptations cardio doesThe weekly target: 2-3 hours of strength training, 150-200 minutes of zone two cardio, 1-2 hard intervals near 80% max heart rate, and one all-out explosive effortYou can be muscular, lean, and still have poor cardiovascular health — muscle and mitochondrial fitness are largely independent, and both need direct trainingSupport Your Mitochondria with BEAM MineralsYour mitochondria need key minerals — magnesium, iron, copper, and zinc — to actually generate the energy your body runs on. BEAM Minerals is a liquid mineral supplement Dr. Anthony takes daily for steadier energy and better recovery. Head to beamminerals.com/fitfamily and use code FITFAMILY for 20% off your first order.Want To Change Your Life? Check Out FF30X!FF30X is a simple, sustainable, and specific weight loss program designed especially for busy men over 40.With short metabolic workouts, an easy-to-follow meal plan, and an accountability team there for you every step of the way, FF30X can help you lose weight, regain energy and vitality, and live life to the fullest. Click here to see everything you get when you join FF30X.*Please know that weight loss results and health changes/improvements vary individually; you may not achieve similar results. Always consult with your doctor before making health decisions. This is not medical advice - simply very well-researched information on longevity training, muscle health, and healthy aging.

How much time do you spend looking at a screen when you'd rather be making eye contact with your patient? In this MedAxiom HeartTalk, R. Kannan Mutharasan, MD, MBA, FACC, FAHA, cardiologist at Northwestern Medicine, shares how AI is helping clinicians stay focused on patients and uncover insights that could lead to earlier diagnoses. As the technology advances, the real work of realizing AI's potential in everyday cardiovascular care is just beginning.

Today, I'm joined by Chris Kiple, CEO of Solius Labs.   A decade in development, Solius's FDA-cleared UVB light therapy device personalizes dosage by skin type, aiming to replicate the benefits of sunlight while minimizing carcinogenic risk.    In this episode, we discuss sunlight as a foundational pillar of health and longevity.    We also cover: Why sun avoidance is deadlier than smoking Designing a skin scanner for personalized UVB dosing Moving UVB therapy from clinical dermatology to consumer health Subscribe to the podcast → insider.fitt.co/podcast  Subscribe to our newsletter → insider.fitt.co/subscribe  Follow us on LinkedIn → linkedin.com/company/fittinsider    Website: www.solius.com  Instagram: https://www.instagram.com/soliuslabs    -   The Fitt Insider Podcast is brought to you by EGYM. Visit EGYM.com  to learn more about its smart fitness ecosystem for fitness and health facilities.   Fitt Talent: https://talent.fitt.co/  Consulting: https://consulting.fitt.co/  Investments: https://capital.fitt.co/    Chapters: (00:00) Introduction (00:29) Swedish longevity study (01:20) Chris background and Solius overview (02:05) UVB light therapy foundation (04:00) 10-year development and timing (05:07) Sun exposure evolution and skin type (08:10) Solius technology and personalized dosing (09:35) Skin scanning and dosing mechanism (11:00) FDA clearance and safety focus (12:40) OTC vs. prescription positioning (14:15) Safety risk contextualization (15:42) Healthcare partnerships strategy (17:50) Dermatology focus (19:00) Orthopedic and cardiovascular applications (20:32) Longevity clinic partnerships (22:35) Swedish and UK biobank studies (26:00) Hormone production benefits (27:20) Cardiovascular and nitric oxide improvements (28:30) Microbiome diversity impact (31:15) Platform evolution and future devices (33:20) Team-building and advisory board (34:45) Listening to early users (36:40) Where to find (38:07) Conclusion

Some board questions aren't testing whether you know the most common diagnosis. They're testing whether you can recognize the one you can't afford to miss. In this minisode, I review high-yield cardiovascular red flags, including the classic presentations of myocardial infarction, deep vein thrombosis, and pulmonary embolism, so you can quickly identify these medical emergencies on your NP boards and in clinical practice.                  Follow us on Instagram: instagram.com/smnpreviewsofficial

This week's replay episode reviews the notion of the underrepresented in medicine physician and the decision to pursue pediatric cardiology. How would improved representation amongst the congenital heart work force result in better outcomes for patients? How does a diverse workforce foster improved communication with patients? What are some practical steps that can be employed to improve representation in the field? We speak with  Dr. Ogochuckwu M Ezeoke Cox, MD of U. Mass about recent essay on this vital topic.https://doi.org/10.1007/s00246-023-03144-7

Can one exercise help lower blood pressure naturally? Discover a simple exercise that can help support healthy blood pressure and cardiovascular health.