Podcasts about arterial

No episódio de hoje do Check-up Semanal, o Dr. Ronaldo Gismondi, editor-chefe médico do Portal Afya e do Whitebook, comenta os principais destaques recentes em Cardiologia, com foco em tromboembolismo venoso, biomarcadores cardíacos, fibrilação atrial, parada cardiorrespiratória e prevenção secundária do AVC.Falamos sobre o estudo MODS e a proposta de um novo protocolo com D-dímero para suspeita de TEP, as potenciais aplicações da razão cTnI/cTnT na interpretação da lesão miocárdica, a comparação entre os escores HAS-BLED, ORBIT e DOAC-score para avaliação de risco hemorrágico na fibrilação atrial, os resultados de longo prazo do estudo COACT após PCR sem supra de ST e as novas estratégias para otimização da pressão arterial após AVC ou AIT.Leia na íntegra os artigos mencionados hoje:Existe diferença no risco de sangramento entre rivaroxabana e apixabana no TEV?A razão cTnI/cTnT na lesão miocárdicaQual o melhor escore para predizer sangramento na FA?Angiografia imediata versus tardia após PCR em IAMSSST – COACT trialOtimização da pressão arterial após a fase aguda do AVC: novas fronteiras

Sano y Veracruzano - Hipertensión Arterial by Radiotelevisión de Veracruz

Commentary by Dr. Jian'an Wang.

PROGRAMACIÓN DE ESTA EMISIÓN: BLOQUE 1: SER MÉDICO HOY Nos acompaña el DR. JORGE GALÍNDEZ (@jorgegalindez), un entusiasta catedrático y Médico Distinguido de la ciudad de Rosario. Especialista en Clínica Médica y Terapia Intensiva. Máster en Sida por la Universidad de Barcelona y Profesor Adjunto de la UNR. Un análisis profundo sobre la vocación y la salud en los tiempos actuales. BLOQUE 2: HIPERTENSIÓN ARTERIAL, LA PANDEMIA SILENCIOSA ¿Cómo prevenir para lograr una vida y longevidad saludable? Dado que se detecta en seres cada vez más jóvenes, estaremos junto a un destacado experto en cardiología de la Sociedad Argentina de Cardiología: el DR. SEBASTIÁN OBREGÓN (@drsobregon @sac_cardiologia). Claves esenciales, prevención y conciencia en nuestro cuerpo para sumar calidad de vida además de longevidad. Marisa Patiño www.marisapatinoambassador.com.ar Embajadora de Paz UNESCO / Autora #neuroEmpoderHadacuantica Investigadora Certificada ORCID 0009-0003-0607-8837 NeuroEmpoderARTE / Mentora / Conferencista Internacional certificada por RedMundialConferencistas / Fundadora, CEO, ESPERANZA ARGENTINA.

Send us Fan MailIn the time it will take you watch this episode, over 2,000 people around the world will die from diseases driven by arterial plaque. But what if we could actually remove the toxic cholesterol already trapped inside arteries?Today we're diving into one of the biggest unsolved problems in medicine and aging: how do you actually remove arterial plaque instead of merely slowing its progression?Cardiovascular disease remains the world's leading killer, despite decades of statins, anti-inflammatory drugs, and newer RNA-based therapies. Most existing treatments help manage cholesterol and reduce risk, but very few directly target the toxic debris already embedded inside plaques.But what if we could literally extract some of the most dangerous oxidized cholesterol molecules from the body?My guest today is Dr. Matthew ‘Oki' O'Connor, Ph.D. - CEO and Co-Founder of Cyclarity Therapeutics ( https://cyclaritytx.com/ ), a biotech company developing engineered cyclodextrin molecules designed to bind and remove 7-ketocholesterol, or 7KC - a toxic oxidized cholesterol strongly implicated in atherosclerosis, inflammation, plaque instability, and even broader age-related diseases.Just recently, the company presented first-in-human clinical data at the American Heart Association Vascular Discovery Scientific Sessions showing dose-dependent urinary excretion of 7KC - potentially the first clinical evidence that this toxic molecule can be safely mobilized and removed from the human body.We'll discuss what 7KC actually is, why oxidized cholesterol may be a root driver of cardiovascular disease, how engineered cyclodextrins work like molecular “sponges,” what the new human data really shows - and what it would mean if medicine could move from slowing plaque progression to truly reversing it.#HeartDisease #Atherosclerosis #Longevity #CardiovascularDisease #PlaqueReversal #AgingResearch #Biotech #Cholesterol #OxidizedCholesterol #7Ketocholesterol #Cyclarity #Healthspan #PrecisionMedicine #AIinBiotech #DrugDiscovery #PreventiveMedicine #Cardiology #AntiAging #Lifespan #MedicalInnovation #SENS #FoamCells #Plaque #HeartAttack #StrokePreventionSupport the show

Neza invita a intercambiar estampas del Mundial 2026Cuba reporta 100 mil pacientes en espera de cirugía Más información en nuestro Podcast#grc

SURGICAL EDUCATOR'S ACADEMY Advanced Online Surgery Masterclass Upper Limb Ischemia Overview ✔️Upper limb ischemia is significantly less common than lower limb ischemia with a ratio of approximately one to nine due to rich collateral networks and a lower workload. ✔️The vast majority of cases involve small vessel occlusive diseases affecting palmar and digital arteries while only ten percent involve large vessel occlusive disease.✔️ Common etiologies include Raynaud phenomenon and thoracic outlet syndrome plus thromboangiitis obliterans which is also known as Buerger disease. ✔️Diagnosis is primarily based on history and physical examination supported by non invasive imaging such as duplex scans and computed tomography angiography.Raynaud Phenomenon ✔️This is a dynamic vasospastic disorder of the small arteries and arterioles triggered by cold exposure or emotional stress. ✔️It is characterized by a pathognomonic triphasic color change where the digits turn white due to ischemia then blue due to deoxygenated blood and finally red due to reactive hyperemia. ✔️Primary Raynaud or Raynaud disease is idiopathic and symmetric and benign typically affecting young women without causing tissue loss. ✔️Secondary Raynaud or Raynaud syndrome is associated with underlying connective tissue diseases like scleroderma and carries a high risk of digital ulcers or gangrene. ✔️Management focuses on patient education and warmth and smoking cessation with calcium channel blockers like nifedipine as the first line pharmacotherapy for moderate to severe cases.Thoracic Outlet Syndrome ✔️This condition involves the compression of the neurovascular bundle as it exits the chest through the scalene triangle. ✔️It is classified into three types including neurogenic which accounts for ninety five percent of cases and venous and arterial. ✔️Arterial thoracic outlet syndrome is rare and often caused by mechanical compression from a cervical rib or an anomalous fibromuscular band. ✔️The most sensitive provocative maneuver is the EAST or Wright test where the patient abducts the arm to ninety degrees with external rotation to check for blanching or radial pulse weakening. ✔️Initial treatment for most patients is physiotherapy to improve posture while surgical decompression via rib resection and scalenectomy is reserved for refractory symptoms or significant arterial compromise.Thromboangiitis Obliterans or Buerger Disease✔️ This is a non atherosclerotic and segmental inflammatory occlusive disease of the small and medium sized arteries in the distal limbs. ✔️It predominantly affects young male smokers under the age of fifty. ✔️Diagnostic criteria include a history of tobacco use and onset before age fifty and distal arterial occlusion in the absence of atherosclerotic risk factors or proximal embolic sources. ✔️Arteriography typically reveals a characteristic corkscrew appearance of collateral vessels around the occlusions. ✔️The only definitive treatment that stops the progression of the disease and prevents amputation is absolute and permanent smoking cessation. ✔️Supportive therapies include intravenous iloprost for ulcer healing and sympathectomy to reduce vasospasm and manage refractory pain.Diagnostic and Management Pathways ✔️The diagnostic pathway begins with functional and non invasive tests such as bilateral segmental arm pressures and digital pulse volume recordings. ✔️Duplex ultrasound is essential for dynamic testing in suspected thoracic outlet syndrome while computed tomography angiography or magnetic resonance angiography provides anatomical mapping for surgical planning. ✔️Revascularization is generally successful for large vessel disease whereas small vessel vasospastic diseases are managed with supportive care and risk factor modification. ✔️Selective arteriography remains the gold standard for invasive imaging when planning complex interventions.

La hipertensión es el principal factor de riesgo para enfermedades cardiovasculares, como infartos, derrames cerebrales e insuficiencia renal. Factores como el estrés, el consumo excesivo de sal, el tabaquismo, el sedentarismo y una mala alimentación aumentan el riesgo de padecerla y su detección oportuna es fundamental. En el marco del día mundial de la hipertensión, te invitamos a escuchar El expresso de las 10 el día de hoy, en el que brindamos diversas recomendaciones para su control con la asesoría del Dr.Jorge Eduardo Hernández del Río, Médico con Especialidad en Cardiología con alta especialidad en Ecocardiografia; Encargado del Gabinete de Cardiología del Hospital Civil de Guadalajara Fray Antonio Alcalde y el Dr. Carlos Alberto Arellano Flores, Médico con especialidad en cardiología adscrito a la Unidad de cuidados Coronarios del Hospital Civil “Fray Antonio Alcalde”

Hipertensão Arterial Resistente e Refratária: Como Tratar? by Cardiopapers

Can arterial closure devices transform your OBL workflow and get patients moving sooner? In this episode of the BackTable Podcast, Dr. Mike Barraza sits down with Interventional Radiologist Dr. Dave Johnson to discuss the ins and outs of launching and running an office-based lab (OBL) in Florida. While covering startup logistics, staffing, regulatory requirements, and cost-saving strategies, the conversation centers on how the use of arterial closure devices can streamline workflow, speed post-procedure recovery, and enhance both efficiency and patient care in the OBL setting. --- Get the BackTable apphttps://www.backtable.com/app --- Terumohttps://www.terumo.com/ --- Timestamps 00:00 - Introduction01:31- Launching The OBL04:41- Logistics And Staffing07:14 - Standardizing Supplies11:57 - OBL vs. Hospital Cases15:30 - Patient Experience Benefits17:41 - Efficiency And Throughput20:49 - Closure Devices For Flow23:28 - Early Ambulation With AngioSeal26:14 - Anticoagulation Decisions28:31 - AngioSeal Access Technique30:20 - Avoiding Hostile CFA Access32:19 - Choosing SFA or Radial34:04 - Do You Need Groin Runs36:14 - Closure Device Fundamentals38:53 - Ultrasound Guided AngioSeal45:11 - Post Op Monitoring Checklist --- More about this episode Dr. Johnson explains that some procedures, such as Prostate Artery Embolization (PAE), may still require a hospital setting due to insurance coverage, patient preference, or unique clinical needs. He compares patient experiences in OBLs versus hospitals, emphasizing the advantages of privacy, convenience, and personalized communication in the OBL environment. A major challenge discussed is managing post-procedure recovery and patient throughput with limited holding beds, where femoral arterial closure devices like Angio-Seal are essential for early ambulation and efficient turnover. The discussion highlights best practices for access site selection, ultrasound guidance, and post-closure assessment, providing actionable insights for IR physicians aiming to optimize office-based procedures. --- Resources Cost Comparison of Prostatic Artery Embolization Between In-Hospital and Outpatient-Based Lab Settingshttps://pubmed.ncbi.nlm.nih.gov/39310461/ Prostate Artery Embolization: Indication, Technique and Clinical Resultshttps://pubmed.ncbi.nlm.nih.gov/29975976/ Ultrasound-guided angio-seal deploymenthttps://pubmed.ncbi.nlm.nih.gov/25735527/ --- BackTable Vascular & Interventional (VI) is the go-to podcast for interventional radiologists, vascular surgeons, and interventional cardiologists. Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty. ► https://www.backtable.com/app

Editor's Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from May 2-8, 2026.

Hipertensão Arterial Resistente e Refratária: Como Tratar? by Cardiopapers

Para todos los que se sienten súper cansados, se levantan rápido y se marean o tienen la visión borrosa, en una de ésas, podrían tener la presión baja. De eso, vamos a hablar hoy con el Dr. Manlio Fabio Márquez. Cardiólogo, especialista en arritmias.

O próximo domingo, 26 de abril, é o Dia Nacional de Prevenção e Combate à Hipertensão Arterial, data de conscientização sobre a importância do diagnóstico e tratamento da doença. O Conexão Senado conversou com o médico cardiologista Ricardo Cals sobre as causas e hábitos que podem contribuir para essa condição. Ele explica a doença, que em muitos casos pode ser silenciosa, fala sobre os alertas comuns, os novos entendimentos sobre pressão normal e hipertensão e dá orientações de prevenção e controle.

Calcium Score to Evaluate Arterial Plaque; 50% of Statin Candidates May Not Need Them; Cholesterol Skepticism and Misunderstood Risk; Inflammation as a Key Risk Driver; Combining CRP and LDL for Better Risk Prediction; Why ApoB and Lipoprotein(a) Matter More Than LDL; Patient Case: High Lipoprotein(a) Despite Normal Cholesterol; Understanding Supplements: Red Yeast Rice and Berberine; Niacin: The Disappointing Heart Health Supplement; Amla (Indian Gooseberry) and Simvastatin Comparison; Health = Resilience ÷ Stress; Genetic Variability in Cholesterol Absorption from Food #HeartHealth #Cholesterol #LifestyleMedicine #HealthTalks

The Cholesterol Code is a gripping new documentary from Jennifer Isenhart that challenges one of medicine's most entrenched beliefs. Following Dave Feldman's unexpected health journey, the film dives into the controversy around cholesterol, uncovering new research and raising a powerful question: what if we've misunderstood it all along? In this episode, Dr. Tro, Jennifer, and Dave talk about… (00:00) Intro (02:39) How the upcoming documentary film, The Cholesterol Code, came to be and how Jen crafted the film to be accessible to a wide audience (08:06) How Jen turns scientific data into an engaging film (15:33) The effort and passion Dave Feldman has poured into his research (17:49) Why YOU should watch this film (Jen's answer) (22:37) How Dave went from a curious software engineer to being one of the main forces driving research on cholesterol and metabolic disease (26:24) Coining the term 'lean mass hyper-responder' and founding the Citizen Science Foundation (31:19) Dave Feldman's critics and how to push back against dogmatic medical authoritarianism (44:29) The good and the bad of cholesterol (01:00:36) LDL, ApoB, and plaque progression (01:06:36) Why YOU should watch The Cholesterol Code (Dave's answer) (01:08:06) CAC, CCTA, ApoB, and LDL levels (01:14:08) Medications that reduce arterial plaque (01:16:19) Arterial plaque and the keto diet (01:26:23) The biggest myths that were dispelled in The Cholesterol Code film (01:29:27) Medical professionals who have come around to Dave and Jen's perspective on cholesterol (01:33:32) Outro For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Resources Mentioned in this Episode: THE CHOLESTEROL CODE (documentary film): https://cholesterolcodemovie.com/the-film/ Jennifer Isenhart: The Cholesterol Code (film): https://cholesterolcodemovie.com/the-film/ Fat Fiction (film): https://fatfiction.movie/our-story Dave Feldman: The Cholesterol Code (film): https://cholesterolcodemovie.com/the-film/ Cholesterol Code (website): https://cholesterolcode.com/ X: https://x.com/realDaveFeldman Citizen Science Foundation: https://citizensciencefoundation.org/ Own Your Labs: https://ownyourlabs.com/ Dr. Brian Lenzkes:  Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian:  Website: https://toward.health Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.  Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888  Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://toward.health/community/

What if the pain you're told is "just a muscle cramp" is actually a life-altering vascular emergency? In this high-impact episode of The Heart of Innovation, Kym McNicholas sits down with interventional cardiologist Dr. Hady Lichaa and his patient, Camille, to discuss a Peripheral Artery Disease (PAD) diagnosis that was almost missed until it was too late. Camille was a mom just trying to walk to her car after her son's baseball game, but the claudication pain was so severe it brought her to tears. Despite visiting the Emergency Room twice, she was sent home with muscle relaxers while her leg was actively dying. In this episode, we unpack: The ER Red Flags: Why leg pain is often misdiagnosed as muscle cramps or venous clots. Arterial vs. Venous: The critical question a Nurse Practitioner asked that saved Camille's leg. The Reality of Bypass Surgery: The complex journey of multiple surgeries and complications. Smoking & Vascular Health: The honest truth about the role of smoking and the "Aha!" moment that led Camille to quit for good. Limb Salvage: How to find the right specialist when you are weeks away from an amputation. This is more than a patient story; it's a manual for self-advocacy. If you have leg cramping while walking, heavy legs, or non-healing wounds, do not wait. RECLAIM YOUR HEALTH: 

Dylan Gemelli went from prison to Milan runways to millions of YouTube subscribers — and then a calcium score of 120 and an LP(a) of 330 stopped him cold at 40 years old. In this conversation with Dr. Philip Ovadia, he breaks down what both the biohacking and conventional medical worlds are getting wrong, why confusion is the real enemy of public health, and how he dropped his LP(a) from 330 to 94 without following his doctor's orders. This episode is equal parts cardiovascular science and hard-won life philosophy — and the two turn out to be inseparable.BIG IDEAIf you're not right spiritually, I don't care what anybody says — it's going to be a struggle to fix the other two.Dylan Gemelli Contact info:InstagramDylan Gemelli Biohacking on YouTubeThe Dylan Gemelli PodcastDylan's WebsiteSend Dr. Ovadia a Text Message. (If you want a response, you must include your contact information.) Dr. Ovadia cannot respond here. To contact his team, please send an email to team@ifixhearts.com Pre-Order Stay Off My Kitchen Table at Amazon. Like what you hear? Head over to IFixHearts.com/book to grab a copy of my book, Stay Off My Operating Table. Ready to go deeper? Talk to someone from my team at IFixHearts.com/talk.Stay Off My Operating Table on X:   Dr. Ovadia: @iFixHeartsJack Heald: @JackHeald5Learn more:Stay Off My Operating Table on AmazonTake Dr. Ovadia's metabolic health quiz: iFixHearts Dr. Ovadia's website: Ovadia Heart HealthJack Heald's website: CultYourBrand.comTheme Song : Rage AgainstWritten & Performed by Logan Gritton & Colin Gailey(c) 2016 Mercury Retro RecordingsAny use of this intellectual property for text and data mining or computational analysis including as training material for artificial intelligence systems is strictly prohibited without express written consent from Dr. Philip Ovadia.

Hipertensão Arterial Resistente e Refratária: Como Identificar? by Cardiopapers

En este episodio de Actitud Saludable, el podcast de Hospital Galenia, el Dr. Arturo Morales Bravo, especialista en Angiología, nos habla sobre el pie diabético y la enfermedad arterial periférica, dos condiciones que pueden poner en riesgo la movilidad y la calidad de vida si no se detectan a tiempo. A lo largo del episodio, conocerás por qué se desarrollan, cuáles son las señales de alerta y la importancia de un diagnóstico oportuno, así como las opciones de tratamiento para prevenir complicaciones mayores. Un episodio clave para entender cómo cuidar la salud vascular y actuar a tiempo. El Dr. Arturo Morales Bravo te invita a escuchar el #podcast para conocer más del tema. ¡No te pierdas sus recomendaciones! ¡Disfruta del episodio 309 y continúa escuchando cada uno de nuestros #PodcastsMédicos  preparados especialmente para ti!➡️ ENLACES DE INTERÉSOtros episodios de Actitud Saludable | Lesiones deportivas: Ligamento cruzado anterior

Crestomatía, Grupo Fórmula. Este video es una obra original del Grupo Fórmula, extracción del programa de Janett Arceo y La Mujer Actual. Publicado el día Domingo 04/Abril/2026. Las opiniones y promociones vertidas en este programa son responsabilidad de quien las dice. Foto de @freepik.

Al portal dianasalud.com trobem un article del 2025 que ens ajuda a decidir en quines ocasions podem evitar fer una gasometria arterial a un pacient amb sospita d’insuficiència respiratòria hipercàpnica; això estalviaria una de cada tres gasometries arterials, amb la disminució de complicacions i temps que suposaria. L’article: Journal of Hospital Medicine Things We Do for No Reason: Arterial blood gas testing to screen for hypercarbic respiratory failure https://shmpublications.onlinelibrary.wiley.com/doi/10.1002/jhm.70039First published: 04 April 2025. DOI: 10.1002/jhm.70039 Font: https://doi.org/10.1002/jhm.70039 Transcripció de l’àudio

Confira as principais atualizações da ADA 2026 sobre o manejo da hipertensão no paciente com diabetes, focando nas novas metas pressóricas e evidências para proteção cardiovascular e renal. Neste vídeo, discutiremos como individualizar o tratamento e quais os limiares recomendados para intervenção farmacológica.Endocrinologia descomplicada para médicos e residentes. Aqui você encontra conteúdos sobre atualização médica, casos clínicos e preparação para provas de título.

The advent of newer thrombectomy devices has turned what were once hours-long surgical cutdowns into endovascular cases that last under an hour. In this episode of BackTable, host Dr. Sabeen Dhand is joined by Dr. Shang Loh from the University of Pennsylvania and Dr. Khanjan Nagarsheth from the University of Maryland to discuss the evolution of arterial thrombectomy devices and modern techniques for acute arterial occlusions. --- This podcast is supported by: Inari Medicalhttps://www.inarimedical.com/artix-system --- SYNPOSIS The episode highlights major technological advancements over the past decade, including the development of mechanical and computer-assisted thrombectomy systems. The physicians review key features of newer devices, such as the ability to combine aspiration with stent retrievers, the use of PTFE baskets to reduce distal embolization, and the advantage of maintaining wire access throughout the case. They share strategies for managing specific cases, including acute femoral-popliteal occlusions with distal reconstitution, intraoperative ischemic pain due to flow arrest, trauma-related thrombosis, and cases complicated by extensive calcification and chronic vascular disease. As vascular surgeons, they also discuss the ongoing role of open approaches, outlining when surgical cutdown is indicated and where they prefer endovascular first. The conversation further explores challenges such as acute limb ischemia, stent thrombosis, and visceral artery thrombosis, emphasizing the importance of staying current with rapidly evolving technologies to improve procedural efficiency and patient outcomes. --- TIMESTAMPS 00:00 - Introduction02:04 - Evolution of Arterial Thrombosis Treatment04:11 - New Devices and Techniques10:42 - Case Studies and Practical Applications24:26 - Techniques and Devices for Thrombectomy25:33 - Managing Flow and Patient Safety27:25 - Surgical vs. Endovascular Approaches29:25 - Dealing with Complications and Failures37:50 - Visceral Thrombosis and Advanced Techniques41:09 - Future of Thrombectomy Devices44:27 - Closing Remarks

In this special “PICU Doc On Call Shorts” episode, pediatric ICU physicians Dr. Monica Gray, Dr. Pradip Kamat, and Dr. Rahul Damania break down the concept of Mean Arterial Pressure (MAP). Using a case of a six-year-old in septic shock, they discuss how to calculate MAP, normal pediatric values, and the physiological determinants and clinical significance of MAP. The hosts highlight MAP's role in guiding management of critically ill children, review autonomic and endothelial regulation, and reinforce learning with a board-style question. This episode emphasizes practical bedside application for pediatric interns and ICU providers.Show Highlights:Overview of Mean Arterial Pressure (MAP) and its clinical significance in pediatric critical care.Introduction of a clinical case involving a 6-year-old child in septic shock.Explanation of the formula for calculating MAP and its application to the clinical case.Discussion of normal reference values for MAP in children and their clinical implications.Physiological determinants of MAP, including cardiac output and systemic vascular resistance.Role of the autonomic nervous system in regulating MAP through baroreceptor reflexes.Importance of maintaining adequate MAP for organ perfusion, particularly in critically ill patients.Clinical applications of MAP monitoring and management strategies in the PICU.Summary of key takeaways regarding MAP calculation, physiological determinants, and clinical relevance.Mention of related topics, such as invasive versus non-invasive blood pressure monitoring.References:DeMers D, Wachs D. Physiology, Mean Arterial Pressure. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing.Pediatric Blood Pressure Metrics and Hypotension Thresholds (details the task force data used to derive the 5th and 50th percentile MAP estimation formulas for children)Berlin DA, Bakker J. Starling curves and central venous pressure. Crit Care. 2015 Feb 16;19(1):55.Magder S. Volume and its relationship to cardiac output and venous return. Crit Care. 2016 Sep 10;20(1):271

This week's stories: Smartphone App Catches What Sleep Trackers Miss A 2026 trial found that suvorexant, a popular prescription sleep drug, improves sleep quality scores — but worsens morning alertness and cognitive function while improving afternoon and evening performance. The study used a smartphone app to pulse users throughout the day, revealing a split-time-of-day signal that traditional sleep scales miss entirely. Optimizing your sleep dashboard and optimizing your waking performance are not the same thing. Sources: https://jamanetwork.com/journals/jama/fullarticle/suvorexant-ema-trial-2026 https://www.ncbi.nlm.nih.gov/pmc/articles/suvorexant-daytime-performance Bats Are Breaking the Telomere Model A 2026 bioRxiv preprint on the tropical bat species Molossus molossus found that these animals live unusually long lives with almost no telomere shortening — challenging the assumption that telomere erosion is a universal driver of mammalian aging. Instead, the bats maintain genome integrity through superior DNA repair and oxidative stress management driven by the metabolic demands of flight. Telomere length may be a symptom, not the cause — and the longevity industry has been measuring the wrong thing. Sources: https://www.biorxiv.org/content/molossus-molossus-telomere-longevity-2026 https://www.nature.com/articles/telomere-bat-aging-2026 The Fenugreek Hack That Cuts Glucose Spikes by Up to 20% Soaking fenugreek seeds overnight and consuming them before meals has been shown across multiple small human trials to reduce fasting glucose and post-meal glucose spikes by 5 to 20 percent. The mechanism is dual — soluble galactomannan fibers slow carbohydrate absorption while bioactive compounds improve insulin receptor sensitivity in muscle and liver. It's a cheap, food-grade, CGM-trackable lever that most people have never tried. Sources: https://www.ncbi.nlm.nih.gov/pmc/articles/fenugreek-glucose-clinical-review https://pubmed.ncbi.nlm.nih.gov/fenugreek-insulin-sensitivity-trial The First Longevity Supplement to Move Vascular Age Like Exercise A randomized, double-blind, placebo-controlled trial out of the University of Surrey found that a multi-ingredient longevity stack targeting NAD metabolism, glycation control, and mitochondrial function improved three independent vascular aging markers simultaneously in healthy adults over 40. Arterial stiffness improved by 1.18 meters per second — equivalent to reversing roughly a decade of age-related decline. Blood pressure dropped 6.1 millimeters of mercury, outperforming aerobic exercise, HIIT, the DASH diet, omega-3s, and magnesium in head-to-head comparisons. Sources: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=6241278 https://clinicaltrials.gov/study/NCT06145087 https://novoslabs.com/blog/supplements/novos-core-clinical-trial-results-longevity-supplement https://www.medicalnewstoday.com/articles/longevity-supplement-improves-vascular-aging-markers-clinical-trial-novos-magnesium-gi Carbon Monoxide Exposure Is Up 50% in 2026 — And Most People Won't Know Until It's Too Late Maryland state data reported by CBS News shows emergency room and urgent care visits for carbon monoxide exposure jumped from 167 cases in 2025 to 251 so far in 2026 — a nearly 50 percent increase. CO binds to hemoglobin more tightly than oxygen, quietly starving your brain, heart, and muscles while producing symptoms that mimic fatigue, brain fog, and the flu. The CDC estimates more than 400 Americans die from unintentional CO poisoning every year — and most of them never saw it coming. Sources: https://kffhealthnews.org/morning-briefing/friday-march-6-2026 https://www.cdc.gov/niosh/topics/co/default.html https://www.cbsnews.com/news/carbon-monoxide-exposure-maryland-spike-2026 Fat Plus Carbs Around Training May Actually Be the Metabolic Move A 2026 study found that combining fat with a carbohydrate-rich period during or around exercise improves insulin sensitivity and fat oxidation in the recovery phase — directly challenging the long-held "never stack fat and carbs" rule. The mechanism appears to be a mixed-fuel training effect: the liver and muscle learn to manage glucose and fat concurrently when both are present during high metabolic demand. Context changes the calculus, and the workout itself may be the variable that flips the equation. Sources: https://www.ncbi.nlm.nih.gov/pmc/articles/fat-carb-exercise-metabolism-2026 https://pubmed.ncbi.nlm.nih.gov/fat-carbohydrate-insulin-sensitivity-training All source links are provided for direct access to the original reporting and research. This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on circadian biology, neurodegeneration signals, cognitive training, caffeine strategy, and supplement regulation. Host Dave Asprey connects emerging science, behavioral data, and policy shifts into practical frameworks you can use to build a resilient, adaptable health stack. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: sleep medication daytime performance, suvorexant alertness, sleep score vs performance, telomere aging myth, bat longevity telomeres, DNA repair aging, fenugreek blood glucose, fenugreek insulin sensitivity, CGM glucose hack, longevity supplement clinical trial, vascular aging markers, arterial stiffness reversal, pulse wave velocity supplement, carbon monoxide poisoning 2026, CO detector home safety, environmental toxin biohacking, fat and carbs exercise, macronutrient timing training, insulin sensitivity workout, metabolic flexibility training, biohacking news, longevity research 2026 Thank you to our sponsors! - The One Device | Use code DAVE for $10 off at theonedevice.com/dave - Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave. Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:20 – Trailer 00:57 - Story #1: Sleep Meds & Morning Performance 02:42 - Story #2: Bats & the Telomere Model 04:33 - Story #3: Fenugreek & Glucose Spikes 06:00 - Story #4: Multi-Ingredient Longevity Stack Trial 07:51 - Story #5: Carbon Monoxide: The Silent Threat 09:45 - Story #6: Fat + Carbs Around Exercise 11:25 - Weekly Roundup See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, Gregory J. Tiesi, MD, FACS, FSSO, hosted a discussion about the growing role for transarterial microperfusion (TAMP) as a regional therapy strategy for patients with locally advanced pancreatic ductal adenocarcinoma (PDAC). Dr Tiesi is the medical director of Hepatobiliary Surgery at the Hackensack Meridian Jersey Shore University Medical Center in Neptune, New Jersey. He was joined by:  Anthony Scholer, MD, FACS, FSSO, a surgical oncologist specializing in hepatobiliary surgery at Hackensack Meridian Medical Group and Jersey Shore University Medical Center in Neptune, New Jersey  Eric Pletcher, MD, a surgeon specializing in Complex General Surgical Oncology at Hackensack Meridian JFK University Medical Center in Edison, New Jersey PDAC is a disease in which dense desmoplastic stroma and poor tumor vascularization often limit the effectiveness of standard systemic chemotherapy. Drs Tiesi, Scholer, and Pletcher explained that standard regimens, such as FOLFIRINOX or gemcitabine-based combinations, frequently fail to achieve adequate intratumoral drug concentrations because of these biologic barriers. TAMP aims to overcome this limitation by isolating a segment of an arterial vessel and pressure-mediated transvascular delivery, which would allow for higher local drug concentrations and reduce systemic exposure and toxicity. The experts noted that TAMP is currently being explored primarily in patients with locally advanced, unresectable pancreatic cancer without distant metastases, particularly those who have exhausted systemic treatment options but maintain localized disease. Early clinical studies, including the phase 1/2 RR1 trial (NCT02237157) and the observational RR2 dose-escalation study (NCT02591082), demonstrated that the procedure is technically feasible, repeatable, and associated with lower systemic toxicity compared with conventional chemotherapy. A pooled analysis of these studies suggested encouraging survival outcomes, particularly in patients who received prior chemoradiation, potentially because radiation modifies the tumor microenvironment and improves drug penetration. Lastly, Tiesi, Scholer and Pletcher reviewed the ongoing phase 3 TIGeR-PaC trial (NCT03257033), which is evaluating TAMP as a consolidation strategy after induction chemotherapy and radiation. Preliminary data suggest improved survival and substantially fewer serious adverse effects with TAMP vs continued systemic therapy alone. Although the experts cautioned that the approach remains investigational, they agreed that TAMP may provide meaningful local disease control and potentially expand treatment options and preserve quality of life for patients with this aggressive malignancy. 

Council debated changes to the single-use item bylaw, especially related to drive-thrus. Plus, we discuss a funding cut for Boyle Street, reaction to the police chief's recent trip to Israel, and some new jobs for Amarjeet Sohi and Tim Cartmell.(00:00) - Introduction (01:43) - Ad: Capital Awards (02:23) - Waste reduction update (14:53) - Boyle Street funding cut (20:18) - Ad: GoodMorning (21:21) - Police chief's Israel trip (30:17) - Arterial roads (33:19) - New jobs for Sohi and Cartmell (36:01) - Become a member (37:21) - Close Here are the relevant links for this episode:Audience surveyWhat we learned from Taproot's 2026 audience surveyWaste reduction updateEdmonton's single-use waste rules unpopular — but workingEdmonton ban on disposable items has reduced use of plastic bags and straws: city dataCalgary's single-use items bylaw repealed, businesses no longer required to charge bag feeBoyle Street funding cutBoyle Street housing program to lose Alberta government funding, province seeks new providerAlberta government ends funding for Edmonton housing programPolice chief's Israel tripEdmonton police chief travels to Israel to meet police leadersEdmonton police chief's trip to Israel draws criticism and supportArterial roadsCouncil questions when to expand arterial roads to four lanesNew jobs for Sohi and CartmellSohi lands role at public affairs firm, Cartmell at NAITNAIT's LinkedIn postTim Cartmell's LinkedIn postState of the City 2026Become a memberIndividual MembershipJoin using promo code SURVEY10 by March 31!This episode is brought to you by the IABC Edmonton's 2026 Capital Awards. You've already done the work. Now bring it into focus. The Capital Awards are Northern Alberta's benchmark for communications excellence, recognizing strategy, creativity, and results that stand up to scrutiny. Turn results into recognition! Submit your work by April 12This episode is also brought to you by GoodMorning, one of Canada's largest mattress retailers, founded right here in Edmonton. GoodMorning's first-ever flagship retail store is now open at 144 Mayfield Common NW. It's the best place to see, touch, and test the full collection of award-winning Canadian mattresses. Enjoy a relaxed, no-pressure way to find your next great night's sleep. Learn moreSpeaking Municipally is produced by Taproot Edmonton, the most reliable source of intelligence about what's happening in the Edmonton region. Through curiosity-driven original stories, tailored and useful newsletters, a comprehensive and innovative events calendar, and thought-provoking podcasts, we inform, connect, and inspire a more vibrant, engaged, and resilient Edmonton region.Sign up to get The Pulse, our weekday news briefing. It's free!Want to reach the smartest, most-engaged people in the Edmonton region? Learn more about advertising with Taproot Edmonton! ★ Support this podcast ★

In today's episode, we're talking about cardiovascular health. Heart disease remains the #1 threat to the quality and quantity of life for Americans. And this is not because of a metformin or statin deficiency. We are pumping these drugs out at all time highs, but have yet to make a dent in heart disease. If you are in the traditional medicinal model, you may not be privy to the fact that there are other ways of supporting and invigorating the cardiovascular system and the underlying drivers of heart disease. You can actually improve cholesterol balance, blood sugar, arterial inflammation, and vascular health with natural means. Let's talk about where to start. Two fruit extracts that can help are bergamot and amla. You know I am a big fan of fruit and these two in particular positively influence: LDL cholesterol Triglycerides HDL Insulin sensitivity Arterial stiffness Vascular Oxidative stress You can find these two science-backed fruit extracts in Cardio Supreme.   -------- Connect with Dr. Matt online:  

This week we review a fascinating very long-term surgical follow-up study from the team at Royal Children's Hospital in Melbourne reviewing over 30 year follow-up following the arterial switch operation for the treatment of transposition of the great vessels. What percentage of patients need reintervention by 30 years post neonatal repair? What anatomical sub-types are more likely to be associated with a need for reintervention and why? When intervention is required for neo-aortic or aortic root problems, can these usually be repaired or do they require replacement? Professor Igor Konstantinov from Melbourne shares his deep insights into this complex patient group. DOI: 10.1016/j.jtcvs.2025.09.008

In this episode, Dr. Jockers shares the top seven foods to help clear arterial plaque, lower blood pressure, and reduce heart disease risk. He explains how nutrients like omega-3s, magnesium, and antioxidants play a crucial role in maintaining a healthy cardiovascular system.   You'll learn about the powerful benefits of wild-caught salmon, extra virgin olive oil, and pomegranates for supporting heart health and reducing plaque buildup. Dr. Jockers emphasizes the importance of nutrient-dense, low-toxin foods for optimal artery function.   Dr. Jockers also discusses how vitamins K2, D, and magnesium work together to prevent calcium from accumulating in the arteries, helping to keep your heart in top shape. These foods are essential for anyone looking to reduce their heart disease risk naturally. In This Episode:  00:00 Introduction to Heart Health 03:16 Understanding Artery Health 05:34 Top Artery Cleansing Foods 08:20 Pomegranate Benefits 10:06 Additional Heart-Healthy Foods 13:51 Cooking Tips for Heart Health 14:57 Conclusion and Farewell   If you want to burn belly fat…boost your energy levels…balance blood sugar…or relieve swelling in your legs or feet… Then you need to check out PureHealth Research immediately.   This company makes some amazing health-boosting supplements that are manufactured right here in America. They only use natural, non-GMO ingredients that are backed by the latest science and proven to work.   And right now, you can save 35% on all of their products with this special subscriber-only offer. Just use your exclusive coupon code JOCKERS at checkout.     Fuel your body with PaleoValley's grass-fed meat sticks, the ultimate healthy snack packed with protein and healthy fats to stabilize blood sugar and satisfy cravings. Made without sugar, additives, or preservatives, these meat sticks are perfect for on-the-go, guilt-free snacking. Choose from flavorful options like original summer sausage, garlic, teriyaki, and jalapeno, in both grass-fed beef and pasture-raised turkey. With an optimal omega-6 to omega-3 ratio, these snacks help reduce inflammation and support immune health, energy, and radiant skin. Ready to try? Visit paleovalley.com/jockers for a 15% discount on PaleoValley today!     "Pomegranates contain powerful antioxidants like anthocyanins and oleic acid that help reduce plaque in arteries and support heart health."  ~ Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Save 35% on premium health supplements with code JOCKERS at checkout. Visit purehealthresearch.com. Visit paleovalley.com/jockers for a 15% discount      Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

In this podcast episode, an in-depth discussion is provided on the drug Telmisartan, commonly used for lowering blood pressure. The host elaborates on how it belongs to a class of medications known as angiotensin receptor blockers (ARBs) and stands out due to its 24-hour half-life and partial PPAR-gamma agonist activity.  The episode explores Telmisartan's potential benefits for longevity, including its properties that reduce cardiovascular mortality, renal decline, and metabolic issues. It also compares Telmisartan with other ARBs and addresses its unique ability to improve myocardial efficiency, reduce arterial stiffness, and support neuroprotection. Detailed explanations are given on technical concepts such as pulse pressure and its relevance to arterial compliance, and the necessity to consult a doctor before taking the medication is emphasized.   Telmisartan / ARBs (main topic) Telmisartan — MedlinePlus drug info: https://medlineplus.gov/druginfo/meds/a601249.html Blood pressure meds overview (includes ARBs): https://medlineplus.gov/bloodpressuremedicines.html Key mechanisms mentioned PPARγ (PPARG) — NCBI Gene: https://www.ncbi.nlm.nih.gov/gene/5468 Endothelium + nitric oxide (NO) — NCBI Bookshelf: https://www.ncbi.nlm.nih.gov/books/NBK534266/ Angiotensin / aldosterone / "fight-or-flight" Aldosterone test — MedlinePlus lab test: https://medlineplus.gov/lab-tests/aldosterone-test/ Sympathetic nervous system ("fight-or-flight") — Cleveland Clinic explainer: https://my.clevelandclinic.org/health/body/23262-sympathetic-nervous-system-sns-fight-or-flight Lab tests mentioned in the episode Fasting insulin ("Insulin in Blood") — MedlinePlus lab test: https://medlineplus.gov/lab-tests/insulin-in-blood/ Hemoglobin A1C (HbA1c) — MedlinePlus lab test: https://medlineplus.gov/lab-tests/hemoglobin-a1c-hba1c-test/ C-reactive protein (CRP) — MedlinePlus lab test: https://medlineplus.gov/lab-tests/c-reactive-protein-crp-test/ Arterial stiffness / pulse pressure (longevity framing) Pulse pressure & arterial stiffness as risk predictors — PubMed: https://pubmed.ncbi.nlm.nih.gov/11224702/ Visceral fat resource mentioned Dr. Sean O'Mara website: https://drseanomara.com/   Show Notes   00:00 Welcome to the Hart2Heart Podcast. 01:22 Understanding Angiotensin and Its Effects 02:14 How ARBs Work and Their Benefits 03:00 Unique Properties of Telmisartan 03:36 Comparing Telmisartan with Other ARBs 04:44 Telmisartan's Impact on Endurance and Fat Loss 05:59 Telmisartan and Cardiovascular Health 09:57 Blood Pressure Basics and Pulse Pressure 18:54 Telmisartan's Role in Longevity and Dosing 27:28 Conclusion and Final Thoughts   The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

In this episode of the Metabolic Freedom Podcast, Ben Azadi explains why heart disease is not caused by cholesterol, but by silent inflammation and damage to the arterial lining. Ben breaks down how plaque actually forms, why standard cholesterol labs often miss real cardiovascular risk, and how insulin spikes, oxidized LDL, chronic stress, and gut-derived toxins quietly damage blood vessels over time. He introduces a science-backed “artery repair plate” designed to restore endothelial function and calm inflammation using four key foods: Arugula or beets to boost nitric oxide and improve blood flow Wild-caught salmon to reduce inflammation and stabilize plaque Fermented vegetables to lower endotoxins and support gut-artery signaling Extra virgin olive oil to prevent LDL oxidation and improve arterial flexibility The episode also covers which lab markers actually matter, common foods and habits that damage arteries, and a simple three-day arterial reset protocol to support long-term heart health. Ben emphasizes that the body is not broken. When the right signals are present and inflammation is removed, healing becomes natural.

What happens when one of the toughest challenges in vascular medicine—severe arterial calcification—meets breakthrough engineering? In this episode of Med Tech Gurus, we sit down with Dr. Robert Chisena, Co-Founder and CTO of Amplitude Vascular Systems (AVS). With a PhD in mechanical engineering and a portfolio of five patents, Robert has dedicated his career to tackling one of the most stubborn barriers in cardiovascular health: hardened arterial blockages that resist traditional interventions. From the labs at the University of Michigan to the founding of AVS, Robert shares how he and his team are developing a next-generation intravascular lithotripsy platform designed to fracture calcium safely and effectively—combining the familiarity of angioplasty with the power of shockwave technology. Along the way, he offers lessons on building IP-rich startups, fostering innovation cultures, securing clinical adoption, and navigating the high-stakes path from spinout to commercialization Whether you're an engineer, entrepreneur, or investor in medtech, this conversation shines a light on the strategies, setbacks, and breakthroughs required to transform a complex clinical challenge into a scalable, life-saving solution.

Episode Summary This week on Live Like the World is Dying, we have a re-air of the first episode of Live Like the World is Dying, an interview with Kitty Stryker about Anarchist Prepping. Kitty Stryker can be found on twitter at @kittystryker and at http://kittystryker.com/ Margaret Killjoy can be found on twitter at @magpiekilljoy and at http://www.birdsbeforethestorm.net/ Publisher Info This show is published by Strangers in A Tangled Wilderness. We can be found at www.tangledwilderness.org, or on Twitter @TangledWild and Instagram @Tangled_Wilderness and Blue Sky @tangledwilderness.bsky.social You can support the show on Patreon at www.patreon.com/strangersinatangledwilderness Transcript The following transcript was provided by a comrade who wants to help us make this show more accessible: S01E01 Kitty Stryker on Anarchist Prepping Live Like The World Is Dying #0:00:00.0# (Introductory music) #0:00:15.1# Margaret Killjoy: Hello and welcome to Live Like The World Is Dying; a podcast that explores life when it feels like the end times. I say "when it feels like the end times", and I'm gonna get into this more throughout various episodes of the podcast, because of course, the world is always ending. It's always changing the status quo. Always shakes and changes, collapses, rebuilds, all of these things. So sometimes people roll their eyes when you talk about the world ending. And sometimes that makes sense, the world has ended in a lot of different ways. But... It sure feels like the world is ending right now to me and to... Maybe to you and maybe it will, maybe it won't. Obviously what it means for the world to end is a subjective thing. But it's a... It's a stress factor to say the least, on a lot of people's lives right now. Thinking about climate change and thinking about the... The rise of global fascism. So this is a podcast that's gonna explore... Well, how we can live while we feel like the world is dying. For myself and for this podcast I've found that I focus on four different priorities. I focus on living like the world is going to end and that I might not survive, living like the world is going to end and I can try to survive, living like we can prevent the end of the world, and of course, living like maybe the world isn't ending after all. So basically hedonism, prepping, revolution, and not burning all your bridges because... Who knows, the status quo might linger on after all. With this podcast I'm probably going to focus on the middle two of these priorities. I'm gonna focus on prepping and revolution. And I'm going to do that because... Well, I've always sort of wanted there to be more information and more... More going on about anarchist and leftist prepping. Because most of the prepping world is of course steeped in... Not just like right-wing politics, but also right-wing values and individualistic values and of course as an anarchist I believe in the balance between the individual and the community and because of that I don't believe in individualistic survival. I don't believe that the bunker mentality, which we're going to talk a lot of shit on in this podcast over the next couple episodes, is appropriate to most... To most threat models. So I'll be your host, but for the most part I'm going to interview people who know a lot more about a lot of this stuff than me. As for me, I am a prepper I suppose on some level. I keep a small stockpile food. Dried food in 5 gallon buckets in case there's an interruption in... Well, food supplies. I make sure I know where water filtration is. I also keep a to-go bag and... At my house. And I keep another one in my car that's much smaller. Neither of these are a particularly elaborate. They're... They're fairly simple things I put together. And that's... That's more for my own mental welfare than it is like any immediate expectation of crisis. And I also... I live off grid. Which is not something that I'm gonna specifically advocate that anyone else do. I actually live off grid because it just sort of meets my needs here and now in terms of how I like to live. I live about half an hour away from a small city in a cabin I built myself in the woods because I like doing that. I like living that way. I'm an anarchist and that's going to certainly bleed over into the content of this show. I believe in a world without course of hierarchies like the state or capitalism or white supremacy or heteronormativity or... Or any of the intersecting oppressions and hierarchies that rule the world that shouldn't. And so of course, a lot of my... I tell you this because I want you to know my biases because I want you to come to your own conclusions. I have a bias against state and federal aid. I tend to find it to be wildly inefficient. I'm far more interested in creating a society based on mutual aid. And so... And I find agency to be wildly important. I find it very important for us to encourage each other to have agency and so I'm interested in disaster relief or crisis preparation or whatever, that maximizes individual agency, that maximize community agency and... Yeah, that's what's interesting to me so that's what I'm going to be focusing on more. This first episode, our guest is Kitty Stryker who I can let introduce herself. Thanks so much for listening. #0:05:01.9# (Musical transition) #0:05:06.5# Margaret: So today our guest is Kitty Stryker. Well actually, do you want to introduce yourself with your name and pronouns and kind of any political or organizational affiliation you feel like shouting out. #0:05:21.4# Kitty Stryker: Sure. I'm Kitty Stryker, I use she/her pronouns. I'm a... I identify myself as a leftist doomsday prepper. But I'm more of a like... Emergency prepper, street medic. I work with Struggle Of Circus, which is a of bunches of leftists and other sort of radical political groups and a bunch of juggalos coming together to help out at protests and usually do medic related stuff but also be kind of a meat wall around marginalized communities. I identify as an anarchist and... Yeah, I guess I just found it really interesting that when I was looking for communities of leftist to talk to about prepping, there wasn't anything there. #0:06:15.5# Margaret: Yeah that was... I think we ended up kind of finding each other through a similar... I don't actually remember how we first ended up talking about it. Maybe you do. But we've been, for anyone who's listening, Kitty and I have been talking vaguely about how we needed to do something about this... This lack of... #0:06:34.2# Kitty: Lack of information, yeah. #0:06:35.9# Margaret: Yeah. Because so much of the information that's out there about prepping is not really applicable, well, to anyone realistically. But certainly not necessarily applicable to people whose ideology isn't "fuck you, I've got mine", you know? So... #0:06:53.5# Kitty: Right and I think... And it could be actively hostile in forums and stuff. Like places that you wanna go to ask for information and ask for advice become really hostile when people are talking about how much they want to kill antifa or of like... "I can't wait til the race war". It's not really a very comfortable place to ask questions about fortifications. #0:07:19.5# Margaret: Yeah. That makes sense. So why don't we start by kind of talking about the general conception of preparedness and kind of what is leftist or anarchist prepping or preparedness. As... At least as you can conceive it. #0:07:37.7# Kitty: Sure, well, so for me I grew up with parents who are sort of like... Suburban homesteader types, with a mixture of prepping. But are also hoarders so while they have everything you would need in an apocalypse you also wouldn't necessarily be able to find it. So I kinda grew up with the hoarding tendency that they think comes with a lot of prepping. You wanna have lots of things that seemed very important. But also this desire to try to make it organized and make it easily accessible. I realized fairly quickly that while I'm more of a stay-in-place kind of prepper and sort of emergency preparedness person, I also will potentially need to be able to put what I need a backpack and carry it with me. At least for a mile or two depending on the emergency and if I have so much stuff that I can't practically do that without a car, it's not really going to be that useful. I live in earthquake country so I just have to anticipate the roads are going to be kind of a mess. So that was sort of where I came from, was this not very political, camping and also very pagan, getting in touch with earth kind of thing. Like my parents beehives that drives all of their neighbors off the wall. They hate it. #0:09:12.7# Margaret: That's interesting. I've only a couple times been around this, yeah, suburban homesteading idea where you have access to a little bit of land. Not necessarily so much privacy, not so much... Place where you can keep your bees. #0:09:24.5# Kitty: Nope, no privacy. Everyone in my neighborhood is like, "That's the witch house. You can tell because there's thirteen sacred trees in the front lawn. And her dad goes outside and scythes the lawn." #0:09:38.1# Margaret: Wow. #0:09:39.7# Kitty: I don't think he's actually even done that in years so I think it's just an overgrown tangle at this point. #0:09:45.9# Margaret: Well that's even more fun. #0:09:46.7# Kitty: But we have like... We have a pond in there. There's a little herb garden, a veggie garden. We have a crow feeder. It's... It's elaborate. #0:09:56.8# Margaret: I'm imagining this on like a quarter acre, half acre. Is that..? #0:10:00.5# Kitty: Yeah. Yeah, pretty much. With manicured lawns right next to us on either side. #0:10:08.5# Margaret: Well, that's a... #0:10:09.1# Kitty: Really... That's where I was raised. I think that explains a lot. #0:10:13.7# Margaret: Okay. It's an interesting metaphor for being the one person who's... You know, either prepping or being a hoarder. #0:10:22.4# Kitty: I've been the one person for a while. Yeah. But I think that that's in such staunch contrast to doomsday preppers which is what most people think of when they think of prepping. They think of like, "Oh, that's those rednecks in the middle of the really rural areas with their bunker and their nine million guns and their giant water containers." And they're, you know, being completely convinced that there's going to a nuclear war or there's going to be... I don't know. What are some of the other disasters that they're always prepared for? Well, I mean like, definitely race wars. Definitely one of the things. #0:11:09.1# Margaret: Yeah, I mean and that's kind of the... I feel like that's the tell between whether you're talking to a racist prepper or a... Well, obviously if someone's talking about a race war they're clearly racist. But... You know, there's a tell of whether or not they're obsessed with like the... The boogaloo or if they're obsessed with... You know, the possibility of invasion or... System collapse in general. #0:11:32.3# Kitty: Right, right. And like what system collapse looks like. Like what are they actually afraid of, I think is very telling. A lot of times you'll see people say, "Oh, I'm afraid that people are going to come and murder my family for my resources because my resources are so awesome that everyone for miles around is going want to come and murder me." Which, first of all, if that was true I would not be saying it on the internet. That just seems like a bad idea. That's... My boyfriend and I watch doomsday preppers and talk about how we would raid their bunkers because they show us everything. And that just seems very shortsighted, if that is indeed what you are worried about. #0:12:22.2# Margaret: Right, as compared to just kind of showing off and being excited about... Like kind of nerding out about gear... #0:12:27.6# Kitty: I think it's like... Yeah, it's like nerding out and they think it's more of a threat than it is. I don't know. I think... I think it speaks to a desire for conflict that I don't personally have. I don't want to have to use my apartment complex to snipe people. I just don't want to do that. I just wanna be able to grow a garden using a discarded... Shoe organizer from the broken down Ross down the street. That's my type of prepping, rather than preparing for endless violence. #0:13:10.4# Margaret: Yeah, there's kind of a... I feel like one of the main myths or concepts that I'm trying to get across with this podcast... Not a myth I'm trying to get across this, prove that something is a myth, is the bunker mentality is the "I've got mine, fuck you" mentality, that is so common in prepping circles and it's... It's really off-putting because... I mean, even... Even from a pure self-interest point of view it just seems so dumb. So you hole up with your five closest friends in the middle of the woods during the apocalypse, and that's like all fine and good until your appendix bursts and you forget that you're not a surgeon and that your brother isn't a surgeon, you know? And... #0:13:56.0# Kitty: Well you just need more useful friends. #0:13:57.9# Margaret: Well, sure but... #0:13:58.7# Kitty: That's what I did. #0:13:59.2# Margaret: But what if you are the surgeon, right? And then your appendix bursts. #0:14:02.4# Kitty: Well, yeah. Then... Yeah. Then... Then... Well, then you just die. I mean, that's the thing. I think that they... They're so afraid of violence coming from other people that they don't... A, think of the violence that could happen amongst themselves which is kind of inevitable if you're locked in a bunker together. And there's... Especially if there's power dynamics in place and stress, then I feel like there's gonna be some abusive dynamics that come out of that. So if you're not prepared for that, it doesn't really matter how good your resources are. And there's... So that's just even within your unit, and then never mind if you're then expanding out to like... Do you know how to do literally everything in the world? Because you're probably going to help. It's the same as the idea about currency. Everyone's so keen on like... Oh yeah, make sure that you have currency. Make sure you silver buried in your yard. Like... What are you going to do with that, really? Like... I mean... It's cool, I guess. But unless you're going to use that as a brick... I don't understand. #0:15:12.3# Margaret: Well I guess it gets into... In some ways, I think the apocalypse... People who think too much about the apocalypse, whether on they're on the left or on the right, or just bored centrists or moderates or whatever, I think that people are thinking about and imagining clean slates and imagining about how they would like to act and what kind of societies they would like to create, what kind of dynamics they'd like to create. So it's really easy for someone who, say of a libertarian mindset, to be like "Well, of course gold is what matters because we're all going to trade resources. There's definitely going to be market economics after the apocalypse because we're going to institute market... Economics. And then maybe like... Those of us that are like, "Wow, the market's a dumb thing and isn't really particularly interesting to me at all." Like, yeah I have a really hard time imagining that I'm going to be doing much... Even bartering after the apocalypse. Like, I'm... I'm either like rolling with people and sharing shit or I'm keeping shit to myself but like... I'm not gonna be like, "Well, these three bullets are worth that tourniquet," or whatever, you know? At least that's my conception of it. That's when... When I like to imagine the end of the world, which is not actually something I like imagining anymore, but I'm imagining something that is closer to the ideological interest that I have. Which is maybe a fault of mine, maybe that's a blind spot of mine. #0:16:39.5# Kitty: Well, I don't think that's... I don't think it's necessarily a fault. I mean, like one thing that I think when... You know, I have a group friends that we talk about this stuff a lot amongst ourselves. Especially because we're within bicycling distance from each other, so we're sort of like, "Okay, if there is an emergency, we're pretty sure that we could get to each other." But we all have... Slightly different ideas of what we would like to see happen which means we also have a different... Like different ideals and different areas of expertise. And I think that that is actually super helpful. I don't know that I would want to be in a group that everybody thinks the same way, as long as you think cooperatively versus competitively. And for me that's what's important. I don't really care how we get to cooperative instead of competitive, but that's what I want. #0:17:33.5# Margaret: Yeah, that makes sense. So, look, I want to talk more about... Okay, one of the things I really like about prepping in general is that it can be very practical. It's not, it's... Obviously a lot of it is not practical at all. But like... But to take this conversation practically for a minute... Like, what you do... Not necessarily... Both in terms of things that you keep around, but also what are your plans? You talked about bicycling to meet up with your friends. What is... What kind of preparedness do you personally practice? #0:18:05.4# Kitty: So my boyfriend and I talk a lot about what our plans are. Pretty much every three months or so. And we're mostly... And ust to give some context, we're mostly prepping for an earthquake, for a big earthquake, because that's the most likely thing to happen here. I guess there's some possibilities that will end up having a bunch of neo-nazis coming and terrorizing us but I think they've gotten tired of Berkeley and have moved to Portland instead so... We're probably fine for now. So we talk a little bit about what are the risks that are current, what are the resources that are currently around? Maybe... We've been talking about creating a map, like actually getting a map and write, marking down important things that we might want to know where they are when you don't have Google Maps for example. So stuff like that is really important. Like the sort of... Preparing... For immediate needs and also for where you are going to be able to get resources. What area is around that could conceivably be turned into a garden if need be. Which we're actually lucky, we have a park really close by. And we also make a point to know our neighbors. Both our housed and houseless neighbors. So having good relationships with them is really helpful and like giving them ideas of how to be prepared so that we're not overwhelming ourselves trying to take care of them as well as ourselves. So you're trying to match up add the younger folks with older folks or able-bodied folks with people with disabilities so that way there's... It's easier for people to mobilize and so that we know who in our area is going to need help. So that's some of the community planning stuff that's not even focused on my group of hyper-focused friends but just making my environment less chaotic. And so that's sort of like... And again, like a garden, it takes some pruning and some cultivating and a little bit of upkeep but I feel reasonably confident that my neighbors are going to be able to handle themselves. Which is my first big concern because then I can start worrying about things like, what do I personally actually need? One thing that is kind of difficult, I live in an apartment and we don't have a huge amount of space. So I can't have buckets and buckets of freeze-dried food. We do tend to have a lot of canned food, we do tend to have a lot of nuts and dried fruit and stuff like that around so that helps a little bit. It makes it easier for us to find stuff in rubble that we can eat. We also have a... A dresser that we put our prepper stuff in and it's sorted with medic supplies in the first two drawers because that's sort of my specialty... That's my area focus. And then we have sort of more general supplies, so that's where we have LifeStraws and we have bandanas and we have masks for filtering out smoke or disease. We have lots and lots of gloves, we have... Water filtering tablets, we have a bunch different kinds of fire starters. So we sort of put together a compendium of things that we felt would be useful. And then what's probably the least practical thing is my... In the main living room I have a hatchet, I have a walking stick, I have my camping stuff. So it's not all condensed in one place but I have... I do have a spare tent at my partner's house and I have a medic bag. A fully packed medic go-bag that I take to protests in the trunk of my car. So that way I can... I have one medic bag in the house, I have one in the car, and I usually have one at my partner's house. Sometimes I have one at my local bar too but that's the one that usually get used if I go to a protest 'cause that's near downtown. But just having pockets stuff... And then I have a storage unit downtown as well. So I figured it might be more difficult to get into my storage unit but at least it's underground and that would be not a bad place to have some stuff that I don't need immediately but might want down the line, yeah. So... But it's sort of a pack rat... Pack ratty, squirrel type prepping. Of burying little caches... #0:23:27.8# Margaret: I'm impressed because you're... Yeah, you're managing to successfully do in an urban environment what... Well... Something I associate more with the rural environments of... You know, one of the things that I was realizing... #0:23:41.1# Kitty: It's harder. It's harder, but it's only harder if you care about being the only person who can get to it. And I don't really care so much about that. I just wanna have access to it. I'm... Because, for me, I'm someone who... I saw a guy on a scooter get hit by car. I was so glad I had that medic kit on me so that I could actually help him out. And immediately help him out. I'm so glad I had that expertise. So... And actually that's one thing that I also have is a first aid book because, again, I don't know how to do everything. But if I have a book, I can probably figure out how to do most things safely. So... #0:24:26.7# Margaret: What's the book? #0:24:29.4# Kitty: It's an old field manual medic guide, I forget what era. But I prefer to try to go for stuff that's military because... Or serious environmental wilderness strategy guides because then they're not focused on you having access to a full hospital. It's not ideal conditions. Sometimes first aid advice is like, "Oh well just call an ambulance" and it's like well that's not really practical in the sort of situations I'm preparing for so I prefer to look at older stuff. And then take newer knowledge and pack that on top. But knowing how to do some of these things when you don't have electricity, a lot of modern medicine depends on electricity, depends on you having access to different kinds of medications and solutions that might not have. So I think it's kind of... I don't... Until I have to do it in practice I don't know how useful it actually will be. But I'm interested in learning how have people prevented disease... In wartime, in... A forest in the middle of nowhere versus what you you would get trained necessarily if you're getting CPR training for your work. #0:26:08.8# Margaret: Have you taken the wilderness first responder course or anything like that? #0:26:12.4# Kitty: I want to so badly. I'm hoping that I can save up for it or have somebody gift it to me. But that is on my list of, oh my god I would... That be so dreamy. But... I really... I just also am just also am obsessed with medical stuff. I guess that's... That's one thing I would really recommend for people curious about prepping. I would say while it is nice to be able to have information about a bunch of different areas, find the thing that you're really interested and nerd out on that. One of my friends is really, really into finding plants and urban foraging. So that's her area of expertise. It's like, oh, she can tell you every plant you can eat within two miles of your house. And that would be really useful, it's not necessarily something that my brain can hold onto... As easily as medicine stuff. My partner is really good with weapons and... Building shelters. It's not really my area so it's nice to have somebody who can teach me just enough but also has a lot more expertise. #0:27:29.4# Margaret: Yeah, that's something that I... I think about a lot in terms of even just the world I wanna live in. I'm really excited about the idea where we... Instead of having a generalism versus specialization kind of argument, it's another bullshit false dichotomy, probably we should all as much as we can generalize as broadly as we can and then pick the things that stand out to us to specialize in. Like, I don't need to know how to do surgery but I should probably know first... Literal first aid. Like first response... Like there have been a number times in my life where I've... I'm incredibly squeamish, I hate medical things, I hate thinking about it the way that like... Like someone showed me how to use a tourniquet and... You know, I disassociated in order to learn. Because the concept of thinking about like... Arterial bleeding doesn't work for me. But I know that I need to know how to do that so I learn pretty much by disassociating and then kind of when things happen I like disassociate again and then deal with it. #0:28:34.6# Kitty: Yeah, I mean there's some practicality to that. When I was doing medical work at protests I really underestimated how traumatized I was until months later... When I was like, "Wow, I just didn't have feelings for a while." It's a lot and I'm... I love... See, I'm not squeamish at all about that stuff but I'm impatient so like building structures is not my thing. It's like, I could learn how to do it but I don't even put up the tent when I go camping if I can avoid it. So... Knowing that I have a good solid group of people around me who are really excited to do that stuff allows us to do the thing we're excited about but also in case something happens to that person, we know how to do it we just don't like it. #0:29:26.1# Margaret: Yeah. Or at least have a... Can do a rougher version of it, you know? Can do a... I had a... I was just talking to a friend about all of this. I actually don't remember if it's... I'm recordings these interviews out of order from how they're going to play. So I was talking to a friend of mine who's a... A medical professional and he was talking about how in a crisis situation if you have two people, maybe what you want is a nurse and a world class generalist, you know? As like the two people that you need. #0:29:58.8# Kitty: Pretty much. I think having a medic... Like I think everyone should have basic medical training, just basic shit, because that way anybody can do an emergency... Like, okay, "I can put gauze on this and stop the bleeding." That's what I need from people. And every time I go to a protest, people are asking what they could do to help and I'm like, "Just do that. Just do that, only." And help people with sprained ankles and keep them hydrated. 'Cause if you can do all of that then I can focus on stitching someone's head together. That's what I need to be able to be focused on because I'm not the squeamish one. So... Yeah, I think that helps a lot. Also coming up with things for you to do, that gets ignored a lot on prepper forums. At least the ones I've been on. They talk a lot about like, you know, "Okay, you've gotta have all of this foraging skills and you gotta have shelter building and you gotta have all these supplies in order to make all of this stuff," but there are no downtime options. And you're gonna have downtime sometimes. Like you're gonna get sick eventually, if nothing else. So make sure you have stuff to keep your mind busy during those times. 'Cause watching "Alone" for example, I don't know if you've ever seen that one but they put these people by themselves in the middle of the... Was it Canadian wilderness I think for at least the first couple of seasons? And they have to do everything from scratch. They have some supplies on them and a good supply list. But they have to pick like... 1 of 10 items, or 10 different items out of a list of like... pre-approved 50 different things they can have. So have to do a lot of stuff by themselves. And almost every single time the thing that gets to them is just a lack of food and boredom. And if they can keep themselves busy, somehow, like making music or making art or building... Like adding decorations to their shelter, then the fact that they're hungry doesn't bother them so much. But if they don't have anything like that, they're not creative in any way, then the fact that they're hungry literally gnaws away at their brain. So I just think that's a really interesting aspect... Like thinking a lot about mental health in an emergency scenario because I think that gets ignored with a lot of right-wing prepping forums and stuff like that. #0:32:53.6# Margaret: Yeah. Yeah I wonder what... I feel like there's just the deck of card, is what's written about in all the things. #0:33:03.3# Kitty: Yeah, it's always recommended. Always have a deck of cards. #0:33:05.8# Margaret: Which is like... You can tell that they wrote that in the 50's or whatever, you know? #0:33:10.1# Kitty: Right, in that... Part of it's gonna be like, "Oh, like for gambling in order to entertain yourself if... Gambling with the no money that you have. I don't know. It's just... I would much prefer to have... I don't know, Codenames or something. Endless replayability. #0:33:31.2# Margaret: Yeah, I feel like there's a... #0:33:32.1# Kitty: I mean, but... #0:33:32.8# Margaret: Go ahead. #0:33:32.8# Kitty: Let's be honest, I'd be playing Dungeons & Dragons. In my tracker tent as an actual ranger. Playing Dungeons & Dragons. #0:33:45.2# Margaret: You wouldn't play... What's the opposite of it? The dragons play, they play... Humans and Houses? #0:33:51.3# Kitty: Oh, yeah, maybe that too. I don't know, mix them up. Mix them together. #0:33:56.3# Margaret: You'd have roleplaying about what would you do if apartments still existed or whatever? #0:34:00.4# Kitty: Yeah. #0:34:02.7# Margaret: I think that... #0:34:03.3# Kitty: I mean, I guess I don't... I'm not that scared of that. It would be uncomfortable and I'd probably hate it a lot. I'm a house cat. But, you know, I'm not that worried about it either. And I think part of it is because I just made being prepared, knowing where my go-bag is at all times just part of my day-to-day existence. So it's just muscle memory at this point. #0:34:32.8# Margaret: Yeah. Earlier in our pre-conversation, when we talked about what we might talk about, one of the things you brought up is the ableism that exists in a lot of prepping conversations and I was wondering if you wanted to talk more about that. #0:34:46.0# Kitty: Yeah, so I noticed that a lot of discussions on what your go-plan is involves being able to walk long distances. Presumably because they figure walking a long enough distance would get you to area of wilderness, that they feel would be more suitable. I... That is really impractical for a large number of people. People with small children are going to struggle with that. Elderly people are going to struggle with that. People with disabilities are going to struggle with that. Some people with disabilities aren't going to be able to do that. It won't even be just a struggle, it's just impossible. So I think the... We need more diverse resources and we need to talk seriously about how to make this accessible for people who aren't in their... Super hyper fit, in their 30's, ready to charge over a mountain. And in the bay area you could you could walk for eight hours and I don't know that you would find a bit of wilderness... So I don't think that's necessarily the most practical option for all people. #0:36:08.7# Margaret: it's funny to me that all this stuff about going to the wilderness because I live in... Not the wilderness but I very rurally. I live in a house that I built at the end of a... Beyond the end of a gravel road like every stupid stick of my fucking cabin I had to carry up a hill on my back. I actually started building it with a chronic injury and then managed to... Physical therapy my way... This isn't a... Statement about ableism, just the weird stupid shit of building this fucking cabin I live in. #0:36:40.6# Kitty: But looks really cool. #0:36:43.0# Margaret: But there's... Thanks, yeah, no I'm really proud of it and it's funny because actually it's a brilliant place to live during civilization. But if there were some kind of crisis, I would probably get my to-go bag or my car presumably but let's pretend like that's not an option for whatever reason, and I would walk to the city. Because the city is where people are and that is where we can keep each other safe. I think people have this conception of... That people are a danger and that's true, people are dangerous, right? But the wilderness is really fucking dangerous too. And... #0:37:23.7# Kitty: People really underestimate how dangerous the wilderness is. They underestimate how cold it is. The cold will kill you, the wet will kill you. #0:37:34.4# Margaret: Yeah and so getting to... I don't know for certain, it would really depend on the threat, but I would presumably go to a place of higher population so that we collectively can figure out what the fuck to do. And maybe the fact that I have access to certain resources by living on land can become useful to people. And that would be my hope. I could easily imagine a situation where you have, as part of your prepping, you would have... The rural... With rural living access to space. You don't necessarily have access to anything else but you often have access to space and... So you can store tractors and you can store strange devices... Like devices that have very odd and specialized purposes for building or something like that. But then again, the thing I'm slowly learning is that cities have all of those things too. It's just that not necessarily each individual is going to own them. Because not everyone lives on a farm. #0:38:36.4# Kitty: Right. The city owns it or the government owns it. But yeah, there's plenty of parking lots. #0:38:42.5# Margaret: Yeah, that's true. #0:38:45.8# Kitty: So... Yeah. I mean, like... Oh, god. I'm trying to remember what the name of the show was. So I... I watch a lot of prepping and wilderness survival based shows. Somewhat to remind myself that nature is dangerous and also because I find them very amusing. And there was one that was... It wasn't entirely clear if it was a reality show or if it was scripted or both. Pretty sure it was both, but they were in LA. And I forget what they had decided ... The LA one I don't think it was a disease. They had a different calamity happen each season. And in the first season they had a good variety of people. They had several mechanics, they had a couple of nurses and doctors. They had martial arts teachers. So they had a good cross-section of people. And they did decently well surviving in a big warehouse in LA and came up with some incredibly inventive weapons and things. I remember they created a flame thrower out of bits of an old car which was stunning to watch. But then the second season they were in New Orleans, in some of the areas that have been devastated by Katrina. And they had underestimated how swampy it was and how hard it was going to be to get food and how there were tons of snakes and alligators that we're going to kill you. And also that one had a disease element so every once in a while someone would get claimed by a contagious disease and they would just start disappearing. But the thing that really got to them I think is that they didn't have a very diverse group of people. They had a lot of schoolteachers and artists and that's great, that's important stuff, but if they don't have any trade skills as well, they're gonna drop like flies. So it's really important to take your creative energies and learn how to do something that can embrace that but also has a living purpose. #0:41:12.1# Margaret: Yeah. Yeah, as a generalist I think about that where most of my skills are graphic design and audio which is great when you want to start a podcast, if you have been doing electronic music for twenty years or whatever, you know? But I think I've really consciously been working on developing my skills that are not only on a computer, you know? For kind of this purpose. #0:41:39.1# Kitty: Well, hey. Electronic music and audio says to me, making ham radios. Practical and useful. There's always something there, it's just like finding what those things are. Though I will say this, the first season in the warehouse in LA they had a big issue with masculinity. #0:42:04.7# Margaret: I only watched the second season. #0:42:05.4# Kitty: Everybody was... #0:42:06.9# Margaret: I watched the one where they all... #0:42:07.5# Kitty: The first one is great. It's like all these male mechanics shouting at each other about how to fix something better and then this female mechanic just goes and does it. #0:42:16.8# Margaret: Yeah, that sounds like a perfect metaphor. #0:42:19.1# Kitty: And then they when they all brag about how proud that they came up with this idea and she just rolls her eyes and you're just like, "Yup, that's how it would be pretty much." And that said to me a lot about mediation. Knowing how to mediate, knowing your own triggers. Like knowing your own mental health stuff so that you can then navigate other people's mental health stuff. That's also super important. And easy for anybody to do. #0:42:44.9# Margaret: Yeah, yeah I think knowing different organization models. Like I think knowledge and facilitation is a really important skill. I think people basically pick whichever organizational model seems to be practical when the existing larger structure goes away. And I've been in spaces where we haven't been sure how we're going to organize ourselves and I'm surrounded by a bunch of non-anarchists and then I'm like, "Well here's this model where we're all equals but we still actually figure things out." And it just works as compared to I'm pretty sure if someone had been like, "Here's the model, I'm pretty much in charge." And maybe it'll be like some veneer of democracy where he'll be like, and I'm just going to use 'he' for this imaginary patriarch... #0:43:28.5# Kitty: I wonder why. #0:43:29.7# Margaret: He'll be like, "I'm in charge and the we can have a little vote about that if we wanna prove that I'm in charge," you know? And everyone will be like, "Well, he's the one who is offering to get shit done." And what... Of course what people fail to realize is that's like... We get shit done, collectively. Whether it's collectively we do it and someone is taking the credit by being up top, you know? Or whether we do it... So that's one of the things that I think about with prepping. How to... And I think that's maybe one of the things that right-wing preppers are afraid of is they're like... They don't have... The only people skills that they know is this hierarchical system. Well, I guess there's plenty of leftists who also only seem to know hierarchical systems. But... #0:44:13.2# Kitty: I mean it's a pretty... It's a pretty common system. That's why... That's why I kind of enjoy the, everybody gets to be an expert in their own thing so that nobody is super... Nobody can be too pleased with themselves. Keeps everybody humble, I think. #0:44:34.3# Margaret: Yeah. So the one other main question that I... Or thing that I kinda wanna hash out with you for this which is probably gonna be the first episode, everyone who's listening will know whether or not it's the first episode. It will be very embarrassing if this is the seventeenth episode, but... Maybe talk about different threat models. That's... How we we determine what we need, of course, is dependent on what we think is likely to happen and as there's no one-size-fits all. And so you say the primary threat model that you're working with is a natural disaster. Do you want to talk about that or do you want to talk about other threat models or... #0:45:12.8# Kitty: Sure. Well, I think... Okay, a great example is the things that I want for a earthquake is not necessarily what I would want in a tsunami, right? Those are very different natural disasters. As somebody who grew up in hurricane country-ish, you know, it was just really really wet. And having a dust mask would not have helped me in any way. But I would be at much more risk of getting trench foot so that would be like, waterpreoof boots would be way more important. So some of it's knowing your environment and being aware of what your environmental concerns ar. Like living in a city, asbestos is a big fundamental concern. So having dust masks is really important. I feel like I read once that most deaths aren't... In an earthquake, come from inhaling the debris. And that... That causes some of the worst injuries because there's just all of this dust everywhere and... I know that was definitely true with the fires. A lot of people have... Still have some... Some still have breathing problems now from the various fires that were going on in Northern California. So knowing what you need to be concerned about. Like with earthquakes, knowing that the roads might not be super useful to drive on. So having alternative plans for that knowing where your bike paths are. Knowing... If you have a wheelchair for example, maybe thinking of a way to add some tread on your wheelchair might be a practical option. I have a beach cruiser. It's not a racing bike by any means but it's heavy and it's easy to find the parts. And it's really easy to fix myself, that's why I chose that. So thinking about what you can actually do, I think is helpful in figuring out your... Your strategy. I know that I don't know enough about my car to be able to completely dismantle it. However, I do know somebody who does know enough about my car to do that. So I can bike to him and then have him do that. So coming up with those kind of like, "Okay, if this then this, if this then this" strategies helps me at least, I have a very ADHD brain. It helps me have a... A process to go through. Now in California, earthquakes are a big concern especially in this area but fire is also a big concern. And the way I would prepare for a fire versus an earthquake, I would be more concerned about my paperwork disappearing in a fire than an earthquake. Though to be completely honest I'm not that fussed about my paperwork in general. I don't think getting rid of paperwork is the worst plan. But that's not what the government wants to hear from me. So I have... I have some paperwork in a folder that's easy to access if I need to grab something go because my apartment is burning but I wouldn't be as... I wouldn't care much about that if it was an earthquake because in my consideration there would will be enough of a drastic interruption in services for an earthquake that I don't think that that would be an immediate need. #0:49:16.3# Margaret: Yeah and you wouldn't certainly be the only one who has lost their paperwork. 
#0:49:20.4# Kitty: Right, exactly. Exactly. And again, I think that we use paperwork as a penalty for so many people that... Maybe mucking up that system a little bit is a convenient little thing I can do on the side. So I... Yeah, I guess... And all of that is completely separate from thinking of having invaders come and try to take my apartment away from me or something. That... I usually strategise for that by thinking about what my plan are if the cops get even more out of control. #0:50:02.9# Margaret: Right. Like fascist takeovers is on my... On my threat model list, you know? #0:50:08.9# Kitty: Yeah, yeah, totally. And you know... The cops have been pretty shitty around here for quite a while, so... You know, it's been a slowly increasing... Plan. But I mean... For me, I'm not interested in trying to shoot my way through the cops. I have no problem with people who that is their plan, I think it's great that there are people who are inclined that way, but I'm gonna go full rogue. I'm sneaky. I'm going to go to the sewers. I'm not as... I'm not as interested in that kind of direct conflict. So my model for that... Or like my managements for that would be really, really different from natural disasters. And I kind of feel like that are all the things that might actually happen. I mean, I guess a meteor could hit but... Eh. The prepping I do for every other disaster would be fine for that probably. Or I'd be dead. And wouldn't care. So... How about you? What are your... What's your threat model? #0:51:23.0# Margaret: So I live on a floodplain. It's not supposed to be a floodplain but global warming has made it a floodplain. And the mountains... When I first moved to the mountains, I grew up in the foothills, and when I moved into the mountains it... It kind of blew my mind that flooding is a problem because in my mind I'm like, "Well, everything is high up" and actually flooding is at least as much of a problem in... Well, the flooding is a problem in a lot different places, you know hurricanes cause floods, but flash floods in the mountains are very real especially in an era of mountaintop removal mining. which is not immediate thing immediately around me but it certainly affects places within a couple hours of where I live in Appalachia. But, you know, storms... Like the weather patterns are just changing dramatically and by living in rurally I'm not as defended against that in some ways because there's not a large crew of people working to try and figure out how to make sure that the little place that I live is... Is safe. And so we have to do it to whatever... Because you're not supposed to mess with of waterways, we have to do it through the state and all that, but in the meantime our land floods. And so... It flooded a couple days ago and I had to go out and try and prevent it from getting worse through whatever means. And... And I actually had this moment, you're talking about paperwork, I started walking into this flood with my wallet in my pocket. And then eventually realized that that was a bad idea. My wallet does not need to be in my pocket. I'm not going to get asked for my papers or need to purchase anything while I'm walking into this flood and... And so it's a... So natural disaster is like the top... Climate change affecting everything is my top threat model where I live. But fascist takeover is on there and fascist takeover... Is a really different set of problems. #0:53:42.9# Kitty: Yeah. And it's different kind of... #0:53:43.8# Margaret: And a lot of it still comes down to knowing your neighbors. #0:53:46.1# Kitty: It's a different set of prepping as well. It's a totally different set skills. #0:53:50.8# Margaret: Yeah. And I mean there's... And one of the things I was thinking about is... The thing I was really... That I realized, a lot of my... I've spent a lot of my life living outdoors. I was a traveling anarchist living out of a backpack, and I was a forest defender and was a squatter and I lived in a van, and now I live in a cabin. Almost half my life I've lived out... Off grid, essentially. And I was thinking how when in February I'm waist and sometimes chest deep in water, I was thinking how glad I am that just kind of by default prefer certain types of practical clothes. It's funny 'cause I... Most of the time... I built my house wearing a dress. But when I'm like, "Okay it's rainy," and I put my puffy vest and my waders, my muck boots, and wool socks. And I wasn't nearly as concerned about hypothermia, which is a major problem in floods especially in February, just because I wasn't wearing much cotton. And it's funny like because I never think about my outdoors skills. Like how to start a fire with tinder and flint and steel and all that. That's not... I don't really see a version of the world where I'm living in the woods alone and hunting squirrels and whatever the fuck, you know? But there are gonna be moments where I might be like... Needing to not get hypothermia while I'm trying to clear up a dam that's forming or whatever. #0:55:26.9# Kitty: Yeah, yeah. Two pairs of wool socks should be on everyone's list in their go bag for sure. #0:55:34.3# Margaret: Yeah, I keep a second vest... #0:55:35.7# Kitty: And the more wool clothing you have the better. #0:55:39.4# Margaret: But what's funny is than I was thinking that through when you're talking about fires, I was thinking about California, I was like... Well, actually the same clothes that are really good in flood and maybe a tsunami are not good in fire. You don't want to wear synthetic in a fire situation. So... But over all... #0:56:00.1# Kitty: But you actually do wanna wear cotton. #0:56:02.6# Margaret: Yeah. Yeah... #0:56:05.0# Kitty: I remember I used to... I used to blacksmith with my dad and he would be like, "What are you wearing? That's really impractical for this." I'm like, "It's fine. It's cotton, it'll just roll right off. You can't catch fire in cotton." He was like, "That's not really true... But it's more true, I guess." #0:56:22.2# Margaret: It's better than polyester. #0:56:24.0# Kitty: Yes, certainly, yes. #0:56:25.3# Margaret: It's not going to melt into your skin. #0:56:27.9# Kitty: I have melted through so many skirts with some prep butts for sure. And I'm sort of learning at this point that that's... That's a concern. But yeah, I mean that's definitely an area of my prepping that I need to be better about. Is just having practical clothes. I don't have that much in the way of practical clothes that can fold up really small and actually keep me warm or keep me cool. #0:56:59.3# Margaret: Yeah. But sometimes people over... Overestimate the importance of this. I've definitely gone hiking in maxi skirts all time. And every time I go hiking with someone new in a maxi skirt they're like, "Margaret, do you wanna wear that?" And I'm like, "Are you fucking kidding me, I've been hiking in these skirts for the past fifteen years I know what the fuck I'm doing." Yeah, they might get caught and rip on things but whatever, you know? So there's a... There's a... I'm suddenly defensive about like, "Oh no, you don't need practical clothes." I don't know, maybe... Maybe we all need practical clothes. But maybe sometimes... #0:57:31.7# Kitty: You definitely need socks and I would recommend more than one pair of underwear. Probably cotton just for... #0:57:38.9# Margaret: But that's, yeah... #0:57:39.2# Kitty: Keeping your genitals fresh. But other then that... You can figure it out. I mean... But also clothes are not exactly in short supply either. There's a lot of trash fashion that we can pad up to make something acceptable. #0:58:01.8# Margaret: Well, in a lot of disaster areas people gather clothes to bring there and all the people there are like, "Why did you bring us fucking clothes. Bring us fucking clean water. What you doing?" #0:58:12.6# Kitty: Well they're bringing clothes because you can't burn them in India or China anymore, right? So it's like, "Oh, we'll give it to poor people." #0:58:22.1# Margaret: That way we get to feel better and clean out our closet, yeah #0:58:25.7# Kitty: Yup. I mean it's just... I guess that's another... That another threat, is just being buried under stuff. Just trash. Just being slowly buried alive under trash. #0:58:39.4# Margaret: Well that's the... That's the status quo problem, right? There's... If the world doesn't end and it keeps going the way it goes that's also kind of horrible. #0:58:49.7# Kitty: Yeah, yeah. Well, I guess actually another threat model that I think a lot about is disease. Disease is definitely a big concern. We... I live in a city where everyone is on top each other. So... A disease can spread incredibly quickly. I remembered there was a person who went to Berkeley Bowl who had the measles or something and they just quarantined Berkeley bowl. And I was like, "I'm not leaving the house for two weeks, just in case, who knows?" And that's even with having a vaccine. It's just... Knowing that when the electricity fails a lot of things like vaccines are going to become a lot more difficult, if not impossible... #0:59:43.0# Margaret: To acquire or whatever? #0:59:45.1# Kitty: And then... And then it's... Yeah, to acquire, keep them cold. To refrigerate medications, that's not going to be possible. So figuring out that is also something I try to be somewhat aware of. Having alternatives to medication, having alternatives to street drugs also. So knowing about... Knowing how to use Narcan. Knowing a little about... I don't even know how to pronounce that, I've only seen it read... Kratom? #1:00:23.5# Margaret: Kratom I think. #1:00:25.6# Kitty: Yeah, so that has been used by a bunch of my friends when they've been withdrawing from opiates. So having stuff that could work as an alternate... I've always packed some pot in my medic bag even though I don't smoke pot. Because it's so useful for so many different things... That it's worth just having it in there. And that's something that could be a real problem. A bunch of people withdrawing at once... Is a huge problem. A bunch of people getting sick at once is a huge problem. So having alternatives for that stuff is something that I'm looking a lot more into. #1:01:13.4# Margaret: Yeah, that's interesting that... I haven't thought about that. #1:01:16.3# Kitty: And that's what... #1:01:16.3# Margaret: The... Specifically withdrawing. #1:01:18.6# Kitty: That's just really something right-wing people don't think about that. I've noticed this. They're afraid of... Sorry, I forget the actual terminology, again ADHD brain, and I tend to call things... Like I called bars alcohol restaurants, that's just... How my brain works. But there's some doomsday thing that a lot of people are hype on... #1:01:39.4# Margaret: Coronavirus? #1:01:41.8# Kitty: About... No, no, no. I wish it was that, that would make much sense but no. They're just being racist and frantic about that while not thinking about the flu which kills a lot more people. But anyway... No. It's the... It's like a solar flare is going to knock out all of our electricity? #1:02:02.9# Margaret: Oh, 'cause then it'll EMP us or whatever? #1:02:05.4# Kitty: That's the one, yes. There's so many of them who are so focused on that but then they don't think about disease at all. And that just blows my mind because disease is way more likely. #1:02:19.9# Margaret: Yeah, people are bad at threat modeling. #1:02:21.0# Kitty: Within our lifetime we've seen multiple plagues. #1:02:25.0# Margaret: Yeah. I mean it's... #1:02:27.7# Kitty: It's just really surprising. #1:02:29.7# Margaret: I think some of it is about... I mean most of it's that people are bad at threat modeling. But I think some of it is like people... Enjoy certain types of threats. Like preparing for certain types of threats more than others. And also probably enjoy preparing like... For something that makes them feel like they have more agency instead of less agency, you know? If you're someone who... All of your skills are about non-electric things you can be really excited about the power grid going down. But I don't know. #1:03:02.8# Kitty: But I mean... That is... That is another area to think about when it comes to ableism, for example. A lot of diabetics aren't going to be able to get access to their medication. So figuring out how do you deal with that. And I don't think there... I don't know that I have answer to that, I don't know that anybody does. While that's for certain something that I would want to... Know more about. #1:03:28.0# Margaret: I think that's why we have to not... It's why the end of the world is bad. Like disaster is actually a really bad thing. Like people clearly get kind of hooked on it, right, because they suddenly have agency in their lives and they... You know, and... Everything I've ever read or talk to people about, like suicide goes down, like psychotic breaks go down, things like that during crisis. And it's... But it's still, at the end of the day, something that if we can avert it we should. And that's actually why... As much as climate change is going to affect things, there are going to be disasters, there's going to be interruptions in our society, if there's ways we can find to make sure that that doesn't kill so many people or ruin so many lives... Even if it ruins economic systems, maybe, you know... And of course as an anarchist I say this, maybe the solution is to ruin the existing economic system. Although ideally by transferring it over to a system that... You know... So that we still have access to the... The things we need in the meantime. Which is actually, it gets... I'm almost done with this rant. The whole... There's a threat that the whole like... There's a Durruti quote where during the Spanish Civil War... Someone asks him, "Well, what about all the destruction of this revolution?" And he's like, "Well, we're workers, we're not afraid of ruins. Why would we be afraid of ruins, we're the ones who built this city, we can build again." And I think about... Often people are like, well, and this is a tangent 'cause now I'm talking about anarchist society, people are like, "In an anarchist society, how would you have antibiotics?" I'd be like "Well, I don't know, how do we fucking have them now? We'll do that. Or maybe a different way, I don't know." And there's still people in the apocalypse, right? There's still a ton of people in disaster and we all know how to do stuff. And so even if like the electrical grid dies, that doesn't mean there's no power. It doesn't mean there's no hospital, even, you know? There's... Like even... We can... Fix these things and do these things and some of those are already prepared for that. #1:05:43.8# Kitty: Yeah. And I mean... And I think... I guess I would say that while it's good to be prepared, I also think it's important not to psyche yourself out. I think it's important to... Not get too excited about it. Because the fact is a lot of people, a lot of black and brown people especially, disabled people especially, will die. In any kind of disaster that you would want to prep for. That's just... That's how we structured our society and that is going to happen. So I think that that is something to be aware of before getting too thrilled about... The end of the world, right? So that you're kinda saying some really fucked up stuff at the same time. And frankly I don't know that I would survive a disaster like that. But I do know that I don't think I could do it by myself. I do think I could do it with community. And I think that that's why I'm so focus on community and mutual aid. I read A Paradise Built In Hell and it's this really interesting book that looks at different disasters and kind of has that... Isn't it interesting how a disaster happens and people come together and help each other even when everything has gone shit. And how... I think this was kinda the intention of the author of this book but she does seem to point out a lot... Isn't it also interesting how often the government steps in and tells them to stop doing that? So no, that is not okay. And will actually murder people to prevent them from helping each other. And I think that... That's something I'd consider as sort of a secondary threat model is... The government trying to prevent people from actually doing okay without them. It's like an ultimate abusive relationship. And figuring out how to deal with that... When you're being funneled into resources that are not ready to handle them. Yeah, so I mean, you know, it's a lot. #1:08:25.9# Margaret: Well this is a... This is a really good... This is going to be the first episode and... So I think we've covered a lot of... Thanks for helping me kind of... Almost like set up what this show will hopefully drill down more about and yeah, thanks so much for... Talking to me about all this stuff today. #1:08:46.8# Kitty: Yeah, thanks for having me. I'm glad we could kind of work out... Sort of, here's all of the issues for... Here's a selection of all of the issues. But wait, there's more. #1:08:58.8# Margaret: Yeah, no, exactly. #1:08:59.1# Kitty: I'm looking forward to seeing the series. It should be pretty cool. #1:09:03.7# Margaret: Cool. Alright, well... Thank you so much. #1:09:06.5# Kitty: Thank you. #1:09:08.0# (Musical transition) #1:09:11.7# Margaret: Thanks for listening to the first ever episode of Live Like The World Is Dying. If you enjoyed the podcast, please tell your friends. Tell iTunes, tell Apple podcasts, tell whatever platform you get your podcasts on that you liked the podcast by subscribing, by reviewing it, by rating it and all of those things. It actually makes a huge difference and I think it'll especially a huge difference for the first couple episodes of a podcast. If you'd like to see this podcast continue, you can support me on Patreon. I... I make most of my living through my Patreon which allows me to spend my time creating content and I'm wildly, wildly grateful that that's something that I get to do with my life. In particular, I would like to thank Chris and Nora and Hoss the dog, Willow, Kirk, Natalie, and Sam. Y'all really make this possible and I can't thank you enough. Alright, thanks so much. And join us next time. #1:10:10.0# (Outroductory music) This podcast is powered by Pinecast. Try Pinecast for free, forever, no credit card required. If you decide to upgrade, use coupon code r-69f62d for 40% off for 4 months, and support Live Like the World is Dying.

Q-BANK: https://patreon.com/highyieldfamilymedicineIntro (0:35),Venous leg ulcers (1:45),Arterial (ischemic) ulcers (2:58),Diabetic foot ulcers (4:42),Pressure injuries (6:10),Pyoderma gangrenosum (8:24),Burns (9:36),Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis (13:12),Warfarin necrosis (14:33),Necrotizing fasciitis (15:21),Rocky Mountain Spotted Fever (16:22),Erythema nodosum (17:35),Lipoma (19:08),Epidermal inclusion cyst (20:00),Dermatofibroma (20:51),Cherry hemangiomas (21:52),Seborrheic ketatosis (22:37),Actinic keratosis (23:41),Basal cell carcinoma (24:47),Squamous cell carcinoma (26:24),Melanoma (28:05),Kaposi sarcoma (30:29),Mycosis fungoides (31:26),Practice questions (32:50)

Novo Quadro de Qualidade apresenta estratégias para fortalecer cuidados cardiovasculares nas Américas; iniciativa pode prevenir 400 mil mortes até 2030; modelo já está ativo em 33 países da região.

The JournalFeed podcast for the week of Dec 8-12, 2025.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday's Spoon Feed:Personalized hemodynamic resuscitation targeting capillary refill time (PHR-CRT) over a 6 hour intervention period demonstrated less need for organ support in patients with septic shock at 28 days.Wednesday's Spoon Feed:The EVERDAC trial found delayed invasive blood-pressure monitoring is noninferior to early arterial catheterization in patients with shock in terms of 28-day mortality.

BUFFALO, NY — December 12, 2025 — A new #research paper was #published in Volume 17, Issue 11 of Aging-US on November 14, 2025, titled “Methylglyoxal-induced glycation stress promotes aortic stiffening: putative mechanistic roles of oxidative stress and cellular senescence.” The study was led by first authors Parminder Singh of the Buck Institute for Research on Aging and Ravinandan Venkatasubramanian of the University of Colorado Boulder, with senior contributions from corresponding authors Pankaj Kapahi (Buck Institute for Research on Aging) and Zachary S. Clayton (University of Colorado Boulder and University of Colorado Anschutz Medical Campus). The researchers investigated how methylglyoxal (MGO), a toxic byproduct that builds up in blood vessels with age or metabolic dysfunction like diabetes, contributes to artery stiffening. Their findings are especially important to aging and diabetes-related cardiovascular risk. Aortic stiffening, which reduces the flexibility of the body's largest artery, is a key predictor of cardiovascular disease in older adults. The research team used young and aged mice to study how MGO affects vascular health. In young mice, chronic exposure to MGO increased aortic stiffness by 21%. However, when treated with Gly-Low, a supplement containing natural compounds such as nicotinamide and alpha-lipoic acid, this stiffening was completely prevented. Gly-Low also reduced the buildup of MGO and its harmful byproducts, particularly MGH-1, in both blood and tissue. “Aortic stiffness was assessed in vivo via pulse wave velocity (PWV) and ex vivo through elastic modulus.” The research showed that MGO's damage goes beyond structural changes. It also caused the endothelial cells that line blood vessels to enter senescence, a state in which cells stop dividing and begin releasing inflammatory signals. This led to lower levels of nitric oxide, a molecule essential for blood vessel relaxation. In human vascular cells in lab culture, Gly-Low reversed these aging-like changes and restored nitric oxide production. In older mice, which naturally develop stiffer arteries, Gly-Low treatment during four months significantly reduced stiffness and lowered MGO and MGH-1 levels. This suggests that Gly-Low may help slow or even reverse vascular aging by reducing glycation stress. The study also identified the glyoxalase-1 pathway as a critical mechanism. This is a natural detox system that helps clear harmful molecules like MGO. Gly-Low appeared to boost this pathway. When the pathway was chemically blocked, Gly-Low's protective effects disappeared, confirming its role in the process. Overall, the findings highlight glycation stress as a modifiable contributor to vascular aging. The results suggest that natural compound-based therapies, like Gly-Low, may offer a potential strategy to protect arteries from age- and diabetes-related damage. DOI - https://doi.org/10.18632/aging.206335 Corresponding authors: Pankaj Kapahi - pkapahi@buckinstitute.org; Zachary S. Clayton - Zachary.Clayton@cuanschutz.edu Abstract video: https://www.youtube.com/watch?v=i_rtq8eIb8c Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Send us a textWelcome back Rounds Table Listeners! In this solo episode, Dr. Mike Fralick discusses a recent trial examining whether noninvasive blood-pressure monitoring is noninferior to early insertion of an arterial catheter in patients with shock admitted to the ICU. Here we go! Deferring Arterial Catheterization in Critically Ill Patients with Shock (0:00 – 11:05).The Good Stuff (11:06 – 11:59):We've launched Critical Care Trial Files! https://criticalcaretrialfiles.substack.com/Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

In this episode of the St Emlyn's podcast, hosts Iain Beardsell and Simon Carley review blog posts from August and September. They reflect on their experience at the BASICs Conference, highlighting discussions on resuscitation science and new resuscitation council guidelines. Topics covered include the physiological-targeted resuscitation, arterial line placements during cardiac arrest, the PECan abdominal trauma rule in pediatric emergency care, intra-arrest stellate ganglion blocks, hydrofluoric acid burns treatment, and pediatric status epilepticus. They also delve into the evidence trial on moving patients with refractory out-of-hospital cardiac arrest to hospitals for specialised care, and review discussions on moral injury among emergency responders. Additionally, they mention the upcoming Geckos Global Health and Emergency Care Research Summit and explore the potential future of emergency medicine by 2038. 00:00 Introduction and Conference Highlights 02:55 Arterial Line Placement During Cardiac Arrest 05:27 Pediatric Abdominal Trauma Rule 10:25 Intra-Arrest Stellate Ganglion Blocks 14:35 Moral Injury in Emergency Responders 23:22 Hydrofluoric Acid Burns Treatment 25:38 Ketamine for Pediatric Status Epilepticus 28:57 Refractory Out-of-Hospital Cardiac Arrest 33:59 Global Health and Emergency Care Research 35:09 Conclusion and Future Episodes

This artery cleansing drink is like exercise in a cup! Unclog arteries and support cardiovascular health with one cup of this amazing drink daily. Reverse arterial plaque and prevent a heart attack naturally!0:00 Introduction: How to unclog arteries naturally0:33 What causes clogged arteries?2:21 How to increase nitric oxide3:00 How to reverse clogged arteries8:35 The best drink to unclog arteries10:33 More cacao benefits If you have damage to your arteries, you're at an increased risk for high blood pressure and clots, which can cause strokes and heart attacks. When you visit the doctor for these conditions, they typically address the symptoms rather than examining the root cause.The root cause of plaque in the arteries is endothelial damage. Endothelial damage and inflammation are repaired by plaque, composed of calcium, cholesterol, and protein.Arterial damage decreases nitric oxide levels, resulting in less control over blood pressure and an increased risk of clotting. Around 90% of heart attacks come from clots!Sunlight is vital to increase nitric oxide. Nasal breathing and magnesium are also essential.You can reverse arterial plaque buildup through a process called reverse cholesterol transport. This mechanism transports plaque in the arteries back to the liver for recycling. This process can be sped up with the help of the following:•Niacin •HDL cholesterol•Exercise •Fasting •Low-carb diets •Bile salts Magnesium controls calcium, so increasing your intake can help to remove it from the arteries. Polyphenols protect the endothelial layer of the arteries, and vitamin K2 helps prevent arterial calcification. Cacao powder is the main component of the best drink for your arteries. It's high in flavonols and stimulates enzymes in the body to produce more nitric oxide. Roasted cacao has been shown to increase blood flow to the arteries, similar to the effects of exercise.Cacao is also beneficial for your heart, brain, skin, and other organs and tissues in the body. It has an accumulative effect and can build up in your system over time. To prepare your drink, combine cacao powder in a glass of water. You can drink it cold or warm. Add beetroot juice powder for an additional boost of nitric oxide and an interesting flavor. You can also add a pinch of sea salt and a scoop of magnesium glycinate for the most potent effect! Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the Director of Dr. Berg Nutritionals and author of the best-selling book The Healthy Keto Plan. He no longer practices, but focuses on health education through social media.Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.

Rethinking "default lines" in the ICU

Katarina Zeder, MD, PhD, joins CHEST® Journal Podcast Moderator Matt Siuba, DO, MS, to discuss her research into the ways in which longitudinal pulmonary arterial pressure trajectories inform clinical outcome in patients undergoing kidney transplantation.  DOI: 10.1016/j.chest.2025.05.024 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine. 

When Coach Prime, Deion Sanders, left a recent Colorado game in pain from another blood clot, headlines focused on his toes and his comeback. But few understood what his story actually exposes: the difference between arterial and venous clots — and why that distinction can mean the difference between life, limb, and legacy. On this week's Heart of Innovation, I sat down with Dr. Esteban Henao of Albuquerque, NM, and Dr. John Phillips, interventional cardiologist and co-host, to unpack the science, the stories, and the stakes behind blood clots — timed to World Thrombosis Day. We discuss: – Why Deion's “perfect storm” of diabetes, aneurysmal disease, and hereditary hypercoagulability makes his case so complex – How arterial clots (often linked to PAD and plaque buildup) differ from venous clots that can cause deadly pulmonary embolisms – What warning signs too many patients and clinicians still miss – Why who you are can determine how quickly you're treated — and how equity in vascular care could save thousands of limbs As Dr. Henao said on the show: “If Deion wasn't Deion, there's a good chance he would have lost his leg.” And that's exactly why these conversations matter. Listen to the full show! If you have additional questions about blood clots, call the Global PAD Association's Leg Saver Hotline at 1-833-PAD-LEGS or go to PADhelp.org #deionsanders #coachprime #bloodclots #arteryclot #DVT #peripheralarterydisease #legsaverhotline #globalpadassociation

Editor's Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from October 11-17, 2025.

De acuerdo con la Encuesta Nacional de Salud y Nutrición 2022, la prevalencia de Hipertensión Arterial en adultos es del 48%, y lo más grave es que el 65.5% desconocía su diagnóstico. Por eso, invité a nuestro hematólogo de cabecera para que nos diga qué onda con la circulación y cómo podemos prevenir estos padecimientos. Hosted on Acast. See acast.com/privacy for more information.