Psychoactive chemical
POPULARITY
Categories
In this episode of the Building PA Podcast, co-hosts Jon O'Brien and Chris Martin celebrate five years of podcasting while diving into a critical topic: opioid awareness and pain management in the context of surgery. They are joined by Brand Newland, the CEO and co-founder of Goldfinch Health, who brings a wealth of knowledge and a fresh perspective on how to navigate the challenges associated with opioid prescriptions following surgery.Brand begins by addressing the opioid crisis, emphasizing the need for a shift in how we approach pain management, particularly in surgical settings. He shares insights from his experience as a pharmacist and discusses the founding of Goldfinch Health in 2018, which aims to improve the surgical experience by advocating for better pain management practices that reduce reliance on opioids.The conversation highlights the importance of multimodal pain management strategies, which include using non-opioid medications like acetaminophen and ibuprofen, as well as innovative approaches such as the TLC method (Tylenol, Lyrica, and Celebrex) to manage pain effectively before and after surgery. Brand explains how these methods can lead to quicker recovery times and fewer complications, ultimately allowing patients to return to work sooner—an average of 35 days faster than national benchmarks.Jon and Chris share their personal experiences with opioid prescriptions, illustrating the common issue of being prescribed excessive amounts of pain medication post-surgery. Brand reassures listeners that there are alternatives and encourages them to advocate for themselves and their loved ones when it comes to pain management.The episode also touches on the financial implications of better pain management practices, with Brand discussing a recent study that shows a significant return on investment for employers who implement Goldfinch's programs. This is particularly relevant for those in the construction industry, where physical labor is a daily reality, and managing pain effectively can lead to improved productivity and overall well-being.As the discussion progresses, Brand introduces the concept of enhanced recovery protocols and the importance of preparing for surgery in a way that minimizes pain and anxiety. He shares practical tips, such as staying hydrated and consuming clear liquids before surgery, which can help improve recovery outcomes.Towards the end of the episode, Brand discusses Goldfinch's new initiative, the Billion Pill Fudge Program, aimed at reducing the number of leftover opioid pills after surgery. He emphasizes the importance of safe disposal methods to prevent accidental poisoning, particularly among children.
Oral methadone versus sublingual buprenorphine for the treatment of acute opioid withdrawal: A triple-blind, double-dummy, randomized control trial Drug and Alcohol Dependence Researchers compared oral methadone to sublingual buprenorphine for the management of acute opioid withdrawal. Patients at an inpatient drug treatment center in India were randomly assigned to receive either methadone or buprenorphine titrated over days 1-3 to control opioid withdrawal symptoms. Over days 4-10 medications were tapered and stopped by day 11. Completion of treatment was similar in both groups (83% methadone, 82% buprenorphine). Both subjective (SOWS) and objective (COWS) withdrawal symptoms decreased during the treatment, however the buprenorphine group had significantly greater withdrawal symptoms than the methadone group (p=0.009) at the end of treatment (day 10). Opioid craving also decreased in both groups with no significant difference between groups. Authors conclude that methadone is a safe and effective alternative to buprenorphine for management of opioid withdrawal. Read this issue of the ASAM Weekly Subscribe to the ASAM Weekly Visit ASAM
Navigating the fine line between effective pain control and minimizing harm from opioid medications remains one of anesthesiology's greatest challenges. This episode dives deep into the evolving landscape of perioperative pain management, examining how clinicians can achieve the delicate balance required for optimal patient outcomes.Dr. Paul Guillod joins us to share his perspective as both an anesthesiologist and pain management specialist, highlighting how opioid-sparing techniques create opportunities for interdisciplinary collaboration and improved surgical recovery. We examine the substantial risks of traditional opioid-based approaches: respiratory depression, delayed bowel function, delirium, and paradoxically, opioid-induced hyperalgesia.The episode showcases promising research on multimodal analgesia strategies that target multiple pain pathways simultaneously. By combining regional anesthesia techniques with medications like NSAIDs, acetaminophen, ketamine, dexmedetomidine, and newer options like suzetrigine, clinicians can dramatically reduce opioid requirements while maintaining effective pain control. Real-world implementation of these approaches through Enhanced Recovery After Surgery (ERAS) protocols has yielded impressive results: 50% reductions in in-hospital opioid use, shortened hospital stays, and improved pain scores across multiple surgical specialties.Whether you're a clinician seeking to improve your pain management approach or simply interested in understanding how anesthesia care is evolving to address the opioid crisis, this episode offers valuable insights into creating safer, more effective perioperative experiences. Subscribe to the Anesthesia Patient Safety Podcast and join us in our commitment that no one shall be harmed by anesthesia care.For show notes & transcript, visit our episode page at apsf.org: https://www.apsf.org/podcast/267-beyond-opioids-revolutionizing-perioperative-pain-control/© 2025, The Anesthesia Patient Safety Foundation
In this episode of the NCS Podcast Masterclass series, hosts Jon Rosenberg, MD, and Stephan A. Mayer, MD, FCCM, FNCS, are joined by Carolina B. Maciel, MD, MSCR, and Katharina Busl, MD, MS, professors of neurology at the University of Florida. They explore the evolution of opioid-sparing pain management strategies in patients with subarachnoid hemorrhage and acute brain injury. The conversation highlights Dr. Maciel and Dr. Busl's work with sphenopalatine ganglion nerve blocks and the design of a phase 2 clinical trial investigating this novel technique. The guests also discuss the limitations of traditional analgesic options, the complexities of headache mechanisms in neurocritical care and how targeted interventions may improve outcomes and quality of life for patients in the neuro ICU. The views expressed on the NCS Podcast are solely those of the hosts and guests and do not necessarily reflect the opinions or official positions of the Neurocritical Care Society.
Class-wide label change for opioids; positive results for oral GLP-1; migraine prevention therapy approved for children; FDA removes restriction on Ixchiq for older adults; Modeyso approved for rare brain tumor.
In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Steve Ruston, CEO of Persica Pharmaceuticals. Ruston has been CEO since the company was founded and has been a key player in developing Persica's non-opioid, one-off treatment. In this episode, we discuss the shift toward treating bacterial causes of chronic low back pain, the use of MRI biomarkers in trials, the evolving role of non-opioid therapies amid the opioid crisis, and how Persica's scientific insights and early trial success could drive renewed investment in a historically challenging field. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts.
In 2022, Iowa signed five opioid settlement agreements, with the state eligible to receive $345 million. Other settlement funds have become available since then. On this episode, how will these funds be used.
Wallis Annenberg was a titan in the world of philanthropy. An heir to the Anneneberg family fortune, she served as chairman and president of the Annenberg Foundation since 2009, giving away more than $3 billion in charitable grants to a variety of causes, including the arts, wildlife, seniors, and inner-city youth. But the obituaries celebrating her life and lauding her achievements failed to mention that she was well-known in LA's LGBTQ+ community as a lesbian, and she had given significant and critical support for LGBTQ+ causes. It was a noteworthy example of queer erasure – the tendency to remove LGBTQ groups or identity from the historical record. The queer erasure so bothered her former partner Karen Ocamb – a noted chronicler of the LGBT civil rights movement and the HIV/AIDS crisis that she took to Substack to write about – in a column titled “When Lesbian Philanthropist Wallis Annenberg Helped Save The Gays.” The article drew immediate praise from members of LA's queer community, who were shocked that news outlets failed to mention Annenberg was a lesbian. I interviewed Karen Ocamb about the Wallis she and so many others knew, and about the work Wallis Annenberg did for the LGTBQ+ community. When Lesbian Philanthropist Wallis Annenberg Helped Save The Gays by Karen OcambLA Times Obituary: https://www.latimes.com/entertainment-arts/story/2025-07-28/wallis-annenberg-dead-philanthropist-obituaryNew York Times Obit: https://www.nytimes.com/2025/07/28/us/wallis-annenberg-dead.htmlLA Times follow-up story: "Inside Wallis Annenberg's final days: Opioid stupor, abuse claims and a bitter family feud"The Suppression of Lesbian ^ Gay History by Rictor Norton: https://rictornorton.co.uk/suppress.htmHollywood Turns Out for AIDS Benefit (New York Times, 1985): https://www.nytimes.com/1985/09/20/us/hollywood-turns-out-for-aids-benefit.htmlGay & Lesbian Elder Housing: https://www.gleh.org/Project Angel Food: https://www.angelfood.org/LGBT History: The Briggs Initiative - a Scary Proposition: https://www.glbthistory.org/briggsLGBT History: Lesbian Solidarity During the AIDS Epidemic: https://www.youthco.org/lesbian_solidarity_during_the_aids_epidemicLGBT History: The Blood Sisters - the Unsung Heroes of the AIDS Crisis: https://diva-magazine.com/2024/02/08/the-blood-sisters/LGBT History: Meet Pioneer of Gay Rights Harry Hay: https://progressive.org/magazine/meet-pioneer-gay-rights-harry-hay/LGBT History: The Lavender Effect: Ivy Bottini: https://thelavendereffect.org/projects/ohp/ivy-bottini/What's Next, Los Angeles? is produced and hosted by Mike Bonin, in partnership with LA Forward.
"If there are some of you who have been tricked into the conviction that you have gone too far, that you have had the poison of sin, which makes it impossible ever again to be what you could have been then hear me - I bear testimony that you cannot sink further than the light and sweeping intelligence of Jesus Christ. I bear testimony that as long as there is one spark of the will to repent and to reach, He is there. He did not just descend to your condition. He descended below it that He might be in all and through all things, the Light of Truth."September 5th & 6th COME BACK TO CHRIST EVENT Tickets can be purchased at https://www.comebackpodcast.org/come-back-to-christ-event-september-5-6-utah-valley-convention-center-provo-ut-3/Jason Coombs free webclass, ‘The Secret to Sobriety: How to Break Your Son's Addiction Without Paying $30,000 for Rehab', Register for this free webclass here: https://www.liveunhooked.com/registerServe Clothing code COMEBACK for 15% offhttps://serveclothing.com00:00 A Personal Mission of Rebellion07:25 Lia's Background and Early Life12:26 Struggles with Mental Health and Faith28:54 Embracing Ex-Mormon Content30:10 Turning to Opioids and a New Church43:59 Rediscovering Her Patriarchal Blessing44:55 Returning to the Temple48:12 Messages of HopeIf you have a story to share please contact ashly.comebackpodcast@gmail.comFor business inquiries contact info.comebackpodcast@gmail.comCome Back Team:Director, Founder, & Host: Ashly StoneEditor: Cara ReedOutreach Manager: Jenna CarlsonAssistant Editor: Michelle BergerAssistant Editor: Britt SmallzeArt Director: Jeremy GarciaProduction Director: Trent Wardwell
HR3 Rising Sea Levels, Private Property Rights, Legal Gas Station Opioids 7-31-25 by John Rush
Delaware's Prescription Opioid Settlement Distribution Commission underwent a mass restructuring over the past year.The commission is in charge of distributing the funds awarded to the First State through legal challenges against opioid manufacturers and distributors.After a grant recipient was flagged for potential misuse of funds last year, the commission completely overhauled its grant program and welcomed a new Executive Director Brad Owens.Delaware Public Media's Sarah Petrowich spoke with Owens about the new-and-improved commission, the latest grant cycle and his plans for the commission.
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode1048. In this episode, I'll discuss how often opioid overdose patients also have a benzodiazepine co-exposure. The post 1048: How often do opioid overdose patients also have benzodiazepine co-exposure? appeared first on Pharmacy Joe.
Following our interview with Lectica Co-founder Zak Stein, Rufus interviews Theo Dawson, Lectica's founder and executive director, about her journey into transforming education and the complex and critical science of measuring educational development.Listen above or watch the episode here: About the episode:In this interview Theo Dawson, award-winning educator, scholar, & founder of Lectica Inc. speaks to her rich life story from drop out to conscious birthing doula to working inside of America's premier educational institutions. In her decades long journey, Theo has focused on realising a form of testing that actually supports students—recognising that contemporary 'education' often works in contra to natural learning processes. We 'teach to test' and education as a field often 'memory holes' decades of work to adopt the latest fashion. Join us to explore development and how Lectica have, over three decades, developed new metrics for student development in K-12 which are also offered to professional organisations. Corrections: At 22:39 Theo refers to ‘Dopamine' but means ‘Opioid' At 44:58 Theo refers to 'Abstract Mappings' but Means 'Representational Mappings' Chapters:1:28 Theo's story of growing up during the Vietnam War, leaving home and running with draft dodgers. 3:47 Becoming a mother and organising conscious doulas 6:57 How her life brought her to focus on the injustice of limiting education system 12:00 The ‘memory holing' shadow in education and developmental science 15:00 The contra-Piaget movement in education, new ideas of ‘fairness' in education 18:00 ‘Teaching to the test' 19:41 How learning really works, the role of the dopaminergic system, and how education undermines natural learning 26:19 Developmental science as very recent 36:00 Hierarchical complexity as development 50:00 The dangerous shift in education 59:29 Points of leverage in systems01:02:57 A new system of measurement 01:17:00 Higher complexity does not equate to ethical participation 01:24:45 Is there a limit to human development? Theo Dawson is founder and executive director of Lectica, Inc, a non-profit organization that develops and administers evidence-based, diagnostic, and formative developmental assessments; offers research and assessment services to clients in the private and public sectors; and builds knowledge about learning and its role in the future of society. She received her master's and PhD from University of California at Berkeley and has published widely in the field of cognitive developmental psychology. https://theo-dawson.medium.com/ https://lectica.org/about/cv-theo Rufus Pollock is an entrepreneur, activist and author as well as a long-term zen practitioner. He is passionate about finding wiser, weller ways to live together. He has founded several for-profit and nonprofit initiatives including Life Itself, Open Knowledge Foundation, and Datopian. His book Open Revolution is about making a radically freer and fairer information age. Previously he has been the Mead Fellow in Economics at the University of Cambridge as well as a Shuttleworth and Ashoka Fellow. A recognized global expert on the information society, he has worked with G7 governments, IGOs like the UN, Fortune 500s as well as many civil society organizations. He holds a PhD in Economics and a double first in Mathematics from the University of Cambridge. Find out more about his work on his website: www.rufuspollock.com. Podcast Production:Jacob Kishere of SENSESPACE Studio Get full access to Life Itself at news.lifeitself.org/subscribe
There's been an increase in people giving up their their pets to animal shelters in Wisconsin. The GOP primary for governor won't include former Governor Scott Walker. And a look at how Wisconsin communities are spending their share of a massive opioid settlement.
Episode 197 of The Hitstreak, a podcast where we talk about anything and everything! This week we are joined by the Nationally Recognized Addiction Medicine Physician, Speaker, and Public Health Leader, Dr. Stephen Loyd!Episode in a Glance:In this episode, Dr. Steven Lloyd and I discuss the profound impact of addiction on individuals and communities, emphasizing the importance of recovery, the role of dental care in rebuilding lives, and the need for open conversations about addiction and its stigma. He highlights the opioid crisis, the dangers of fentanyl, and the significance of community support and faith-based initiatives in combating addiction. We also touch on the importance of personal stories in fostering hope and understanding, as well as the need for resources and non-judgmental approaches to support those in recovery.Key Points:- Smiles for Recovery provides essential dental care for those in recovery.- Addiction has caused more deaths than all U.S. wars combined.- The stigma surrounding addiction prevents open discussions.- Genetics, trauma, and opportunity play significant roles in addiction.- Dental health is crucial for rebuilding confidence in recovery.- Shame can be a barrier to recovery but can also lead to humility.- Parents should have open conversations with their teens about addiction.- Fentanyl poses a significant risk, even in small amounts.- Community efforts are vital in addressing the addiction crisis.- There are more individuals in recovery than in active addiction.About our guest: Dr. Stephen D. Loyd, M.D., is a nationally recognized addiction medicine physician, speaker, and public health leader. He serves as Medical Director at Cedar Recovery, New Hope Treatment Center, and The Next Door, and volunteers at Renewal House and Mending Hearts. A graduate of ETSU's Quillen College of Medicine, Dr. Loyd also teaches at ETSU and lectures at Vanderbilt. He's a former Tennessee Assistant Commissioner for Substance Abuse Services and National Medical Director at Journey Pure. As a physician in long-term recovery, he brings personal insight to his advocacy for evidence-based treatment. Dr. Loyd has advised the DEA, FBI, and U.S. Attorney's Office, and his story has been featured in NPR, CBS, The New York Times, and Dopesick, where Michael Keaton's character was partly based on him. He is a Fellow of the American College of Physicians and a White House Advocate for Action award recipient. His mission: change how America sees addiction—and save lives.Follow and contact:Instagram: @drstephen_loydwww.cedarrecovery.comSubscribe to Nick's top-rated podcast The Hitstreak on Youtube: https://www.youtube.com/NickHiterFollow and Rate us on Spotify: https://spotify.com/NickHiterFollow and Rate us on Apple Podcast: https://podcasts.apple.com/NickHiterFollow and Rate us on iHeartRadio: https://www.iheart.com/NickHiter
Co-involvement of stimulants with opioids in North America: A 'silent epidemic' Plos Mental Health The opioid epidemic unfolded in three distinct waves, with the latest being deaths attributed to illegally manufactured synthetic opioids. Using U.S. and Canadian data, this study reviews evidence for a 'silent epidemic' alongside the opioid epidemic that is characterized by the co-ingestion of stimulants including methamphetamine and cocaine leading to an increasing number of deaths. Trends for stimulant and opioid use were analyzed using Joinpoint regression and public interest in the substances was assessed via Google Trends. While stimulant use and its role in deaths are rising, public interest in stimulants has declined since its peak in 2004-05. Co-use leads to more deaths than either drug alone. Urgent strategies are needed to reduce harm and raise awareness among health professionals, policymakers, and the public about the dangers of stimulant-opioid co-use. Read this issue of the ASAM Weekly Subscribe to the ASAM Weekly Visit ASAM
Morning Show 07-29-25 Hour 3 Andrew Donaldson on opioid money by The Watchdog
Got Health Questions or Comments?
In episode 63 we discuss the association between buprenorphine dose and neonatal opioid withdrawal syndrome. Marc B, Marion D, François B, Lakshmipriya L. Is buprenorphine maternal dose associated with neonatal opioid withdrawal syndrome severity? Am J Addict. 2025 Jan;34(1):15-20. We also discuss private equity in health care and nitrous oxide (Galaxy Gas). AMA Journal of Ethics: Is Pursuing Profit Commensurable With Providing Good Health Care? David T. Zhu: presentation on private equity at the 2025 From Research to Recovery Conference. Smithsonian Magazine: The Long, Strange History of Nitrous Oxide, a Popular Drug Users Have Been Inhaling for Hundreds of Years --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ --- Original theme music:composed and performed by Benjamin Kennedy Audio editing: Michael Bonanno Executive producer:Dr. Patrick Beeman A podcast from Ars Longa Media --- This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice. The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. Email: addictionmedicinejournalclub@gmail.com Facebook: @AddictionMedJC Facebook Group: Addiction Medicine Journal Club Instagram: @AddictionMedJC Threads: @AddictionMedJC YouTube: addictionmedicinejournalclub Twitter/X: @AddictionMedJC Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. Learn more about your ad choices. Visit megaphone.fm/adchoices
7/28/25: CODEPINK founder Madea Benjamin: tonight's event – Gaza today. Megan Zinn w/ Forbes Bd Chair Katy Wight "watcha' readin'?" UMass Prof Amilcar Shabazz: the state of reparations in W. Mass. Amherst Town Mgr Paul Bockelman: opioid settlement funds & reparations money.
New data suggests Indiana's college-going rate is down to 51.7%, the lowest in a decade. What does that mean for the state's future outlook?
In this episode of RAPM Focus, Editor-in-Chief Brian Sites, MD, discusses the use of buprenorphine for acute pain management with Thomas Hickey, MD, MS, following the February 2025 publication of “Buprenorphine versus full agonist opioids for acute postoperative pain management: a systematic review and meta-analysis of randomized controlled trials.” Dr. Hickey is full-time staff at the West Haven VA where he is medical director of preoperative evaluation and the PACU, and site director for the anesthesiology residency. Within the VA, he is chairman of the VA New England Healthcare System committee on preoperative evaluation and ERAS, co-chair of the VA's national pain/opioid consortium for research workgroup on perioperative management of medications for opioid use disorder, and a member of the National Anesthesia Program Acute Pain Management Committee. He is board certified in both anesthesiology and addiction medicine. His research interests focus on the overlap between addiction medicine and acute pain management, particularly on the use of buprenorphine for acute pain management. He and his wife are kept busy by their three kids and all their activities. *The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice, and it is not intended to function as a substitute for a healthcare practitioner's judgement, patient care, or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others. Podcast and music produced by Dan Langa. Find us on X @RAPMOnline, LinkedIn @Regional Anesthesia & Pain Medicine, Facebook @Regional Anesthesia & Pain Medicine, and Instagram @RAPM_Online.
We talk with Amanda and Tommy from F Fentanyl, their organization that works tirelessly to bring free naloxone, best known under the brand name Narcan, and education to everywhere from elementary schools to raves. Their efforts are saving lives, part of the reason the opioid overdose rate has been going down in the United States. If you want to watch the video of this episode, check out our YouTube channel @addictionandthefamily. Special Guest: Amanda Nicol and Thomas Guerra.
Biologist Lauren O'Connell studies poisonous frogs, but not just the toxins that make them dangerous. She also studies the neuroscience of their complex parenting. She's learned that tadpoles recognize their mothers by smell and do a “begging dance” when hungry, and that the frogs produce a protein that protects them from their own poisonous chemistry. That protein could help treat overdoses in humans, O'Connell tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Lauren O'ConnellConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Lauren O'Connell, a professor of biology at Stanford.(00:03:34) Why Poison Frogs?Lauren shares what led her to focus her research on poison frogs(00:05:16) Parenting Styles in FrogsThe diverse parental strategies across frog species.(00:08:36) The Role of Opioids in ParentingThe signalling factors in the frog brain that regulate bonding,(00:10:05) Hormones & Gender RolesThe influence of testosterone and estrogen on caregiving behaviors.(00:11:34) Implications for Human ResearchHow studying frogs reveals basic neural blueprints of parenting.(00:13:23) Tadpole's CommunicationThe neural circuits behind tadpole communication and behavior.(00:15:10) Autism Gene Experiments in TadpolesHow genetic changes can alter tadpole social communication(00:17:47) Transparency & Tadpole BiologyObserving tadpole behavior and neural activity via their transparency.(00:20:59) Tracking Frogs in the WildResearch on how frogs navigate back to their tadpoles(00:24:31) Male vs. Female NavigationTestosterone's influence on the ability to navigate more efficiently.(00:25:38) Toxin Tolerance MechanismsA toxin-binding protein that allows frogs to avoid self-poisoning.(00:29:01) Origin of the ToxinsThe origin and mechanisms of the toxins found in frogs.(00:31:15) The Value of Basic ScienceHow studying fundamental science can lead to unexpected applications.(00:33:10) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook
More Than Just Saying 'No' to Drugs and Alcohol: Building a Generation with Purpose Scarlett's guest is Roman Gabriel, president of the Sold Out Youth Foundation, which has a mission of equipping the next generation for success without drugs and alcohol. Roman Gabriel shared his background as the son of an NFL quarterback and discussed his journey to become a successful speaker, author, and host. Scarlett and Roman discuss drug education programs in schools, particularly comparing Sold Out Youth Foundation's online approach with D.A.R.E. and highlighting their five-step curriculum and success in reaching students at critical ages. Roman Gabriel shared his background and experience developing student-centered programs that teach responsibility and accountability through engaging methods, while also discussing the urgent need for national Fentanyl awareness and education due to its impact on youth. Here's how this program changes lives: Focusing on character education programs and the importance of teaching life skills and character traits in schools, particularly in the context of the ongoing Fentanyl and Opioid crisis. Roman's ground-breaking 365 Online interactive public, private, and home school programs using sports, entertainment, and education through school internet technology to deliver a 100% student alcohol /drug abstinence accountable pledge. Students learn life skills training, and overall student fitness, health, and wellness initiatives. All interactive and available the way students like to be entertained and learn, through their phones visually. Learn why Roman's program is more effective than the DARE program and how you can bring it to your school and community! https://soldouttv.com/ Share this important podcast with family and friends. Find out how you can bring this program to your school! Learn more About Scarlett here: https://chooselovemovement.org/
The Beacon 07-17-2025: 'They need to be given the opportunity not to die': Amid opioid crisis, federal cuts put harm-reduction efforts at risk by Nick Carswell
U.S. Immigration and Customs Enforcement has access to medicaid data. Advocates for immigrants in Mississippi say it needs to be stopped.Then, what are the warning signs of someone developing dementia? We speak with a doctor about what Mississippians need to know.Plus, the Trump administration is delaying federal grants that help provide overdose-reversal drugs like Narcan. Hosted on Acast. See acast.com/privacy for more information.
HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast
In this episode, we discuss the evidence, safety, and place in therapy of Journavx® (suzetrigine), a newly approved analgesic with a unique non-opioid mechanism of action and additional considerations for its use. Key Concepts Suzetrigine is a first in its class NaV1.8 sodium channel blocker approved for short-term (14 days or less) pain relief in adults with moderate-to-severe pain. Unlike opioids, suzetrigine is non-sedating and non-dependence forming. Suzetrigine is taken as a whole pill without cutting, crushing, or chewing following a particular dosing schedule where the first dose is taken on an empty-stomach. The most common side effects of suzetrigine include pruritus, muscle spasms, increased CPK, rash, and transient (reversible) eGFR decrease. Suzetrigine goes through CYP3A metabolism and therefore has significant interactions with CYP3A inducers and inhibitors. Use with strong inhibitors and moderate to strong inducers is not recommended. Dose reduction of suzetrigine is required if used with moderate inhibitors of CYP3A. Although not formally adopted in a guideline recommendation, suzetrigine's current place in therapy can be moderate-to-severe acute pain relief in adult patients after NSAIDs/APAP options are exhausted, but before or in place of opioid therapy. References Bertoch T, D'Aunno D, McCoun J, et al. Suzetrigine, a Nonopioid Na V 1.8 Inhibitor for Treatment of Moderate-to-severe Acute Pain: Two Phase 3 Randomized Clinical Trials. Anesthesiology. 2025;142(6):1085-1099. doi:10.1097/ALN.0000000000005460
Welcome to the Opioidology podcast series! First up to bat, ‘Our Opioid Story”. You've heard, seen, and most likely experienced many facets of the Opioid Crisis. The doom, the gloom, and perhaps a pinch of hope. The kidney punches to us healthcare professionals continue, while tightening the constraints on our patients in pain and in recovery like never before, all while more and more heartbeats are continually lost. But how did we really get here? Listen in to this Pain Pod episode for an unbiased, in your face, here's how it is approach to explaining the timeline of the opioid crisis, our opioid story. Come one, come all, to the Pain Pod!!! Pain Guy • www.painguy.us
Pennsylvania health officials have temporarily added nitazenes, a synthetic opioid, to the list of controlled substances in the Commonwealth. Temple University's School of Dentistry is launching a rural dentistry track. A new campus will be located in Schuylkill County, and the goal of the new program is to encourage new dentists to practice in underserved areas of Pennsylvania. The State Department of Labor and Industry reports a slight increase in unemployment in June. Harrisburg's so-called "tent city" could be headed to a new location. Residents of the encampment say they were given flyers, promoting the ability to register for one of 50 to 60 encampment sites on a South 9th Street property, just off Cameron Street. The nonprofit Amiracle4sure recently obtained the land. They say they'll be releasing more details soon, in conjunction with county officials. An 82-year old Pennsylvania man was secretly deported to Guatemala after he attempted to replace his green card, which had been lost, according to his family. The 10th annual Schuylkill County Brew Fest is set for this Saturday (July 26) in Pottsville. Support WITF: https://www.witf.org/support/give-now/See omnystudio.com/listener for privacy information.
In this episode of Grade 1 View, we had the privilege of speaking with Tom Baribeault, DNP, CRNA, a pioneer in the field of opioid-free anesthesia. As the president and founder of the Society of Opioid Free Anesthesia, Tom has dedicated his career to advancing pain management techniques that prioritize patient safety and comfort. Today he'll share how his own clinical curiosity led him to abandon intraoperative opioids altogether, and what happened next. From reducing postoperative nausea to improving respiratory safety, this conversation will challenge you to question the status quo and expand your definition of what anesthesia can look like. Here's some of what we discuss in this episode:
My guest is Dr. Chris McCurdy, PhD, FAAPS, professor of medicinal chemistry at the University of Florida and a world expert on the pharmacology of kratom and other plant-derived medicinal compounds. We discuss kratom's wide-ranging effects, including its use for boosting energy, enhancing mood, managing pain and as a potential opioid substitute, while also explaining its critical safety concerns and addictive potential, especially for kratom-derived/isolate products. We also discuss plant-based compounds more generally for their potential benefits and risks. Dr. McCurdy offers a balanced perspective on kratom and other plant-based and naturally occurring medicinal compounds, highlighting and contrasting their promise for human health with potential serious risks. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David Protein: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman ROKA: https://roka.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Chris McCurdy 00:02:51 Kratom (Mitragyna speciosa), Origin, Effects, Low vs High Doses 00:07:19 Sponsors: David Protein & Eight Sleep 00:10:07 Kratom, Traditional Use vs Commercial Kratom Products, Absorption 00:17:00 Kratom Products, Serving Size, Kids; Semi-Synthetics; Tool: Understand Kratom Product Labels 00:23:16 Kratom Products & Various Desired Effects; Physical Dependence 00:32:53 Different Kratom Usage Patterns, Opioid Dependence 00:36:59 Alkaloid Compounds, Nitrogen, Nicotine; Animals & Self-Experimentation 00:47:47 Sponsors: AG1 & ROKA 00:51:05 Medicine Development, Disconnection from Nature, Product Concentrations 00:59:00 Alkaloids & Natural Products, Opium Poppy, Coca Leaf, Tool: Kratom Leaf vs Extracts (Kratom-Derived/Kratom Isolates) 01:09:06 Is It Safe for Kids to Consume Kratom Products? 01:12:19 Kratom, Energy, Mood & Pain Management, Dose; Caffeine 01:16:56 Respiratory Depression & Kratom Products 01:20:16 Sponsor: Function 01:22:04 Kratom Leaf vs Derivatives, FDA Regulations, Usage Guidelines 01:26:59 Kratom, Alcohol Consumption, Respiratory Failure? 01:29:09 Kratom Alkaloids, Mood & Stimulant Effects, Multiple Pathways for Pain Relief 01:38:17 Plant Alkaloids & Chemical Defense, Kratom & Antifungal Alkaloids; Geckos 01:44:35 White, Red & Brown Vein Kratom, Leaf Processing; Terpenes 01:51:08 Kratom as an Anti-Depressant?; Discontinuing Kratom Use, Opioid Use 01:58:03 Kratom, Drug Interactions & Seizure, Opioids 02:01:51 Cacao Beans, Chocolate 02:09:34 Coca-Cola, Coca Plant & Cocaine, History of Soft Drinks 02:19:49 Career Journey, Pharmacy, Chemistry & Education, Lobelia 02:28:44 Nicotine; Natural Products & Career Journey, Salvia divinorum, Kratom 02:40:22 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
On this week's episode of the Who Are You? Podcast we sat down with TJ Ward. TJ is a father, cohost of the very popular ” Speak Easy Jax” podcast, a Director of Advocacyfor Project opioid at the Jacksonville Chamber of Commerce and so much more. We broke down where the idea to start the Speak Easy Jax podcast came from, what it has been like to sit down with some of Jacksonville's most influential people such as Patric young, Mark Brunell , Ken Babby and more. We also discussed the major opioid issue that is plaguing the USA and Jax, Tj tells us all about project opioids mission to raise awareness of the dangers of opioid/otherstreet drugs and to provide a helping hand to people who may be struggling with active addiction and so much more. Project Opioid is an amazing program that is helping our city become a better place if you or someone you know has beenaffected by the opioid's definitely check them out! For more on TJ, the Speak Easy Podcast and project opioid follow the links below TJ Social media: https://www.instagram.com/tjwardfl/ Speak Easy Podcast: https://www.speakeasyjax.com/ Project Opioid: https://www.facebook.com/ProjectOpioidJAX/ Sponsors: BetterHelpGo to https://betterhelp.com/whoareyou for 10% off your first month of therapy with BetterHelp and get matched with a therapist who will listen and help #sponsored Make sure to turn on your notifications so you don't miss an episode, please share the episode, leave a like, a review and a 5-star rating. All those things help the podcast be seen by more people!For all business inquires or are interested in being on the show please reach out to me at: whoareyoupod@yahoo.com For all updates and information about the podcast:Instagram: https://www.instagram.com/whoareyoupod/ Facebook: https://www.facebook.com/profile.php?id=100089483824865 TikTok: https://www.tiktok.com/@who.are.you.podca?is_from_webapp=1&sender_device=pc YouTube: https://youtube.com/@whoareyoupod?si=qHi5b7UP28YqrqwU All other links: https://linktr.ee/Whoareyoupod
The conversation delves into the complexities of end of life care in combat settings, emphasizing the need for palliative care discussions among military medical personnel. It highlights the challenges faced in recognizing non-survivable injuries, the decision-making process in resuscitation efforts, and the importance of compassionate care for both patients and their loved ones. The discussion also touches on the role of opioids in managing pain and anxiety during end of life care, advocating for a shift in focus from aggressive treatment to comfort and dignity for the patient.TakeawaysEnd of life care is a critical conversation in military medicine.Palliative care is often overlooked in combat settings.Recognizing non-survivable injuries is essential for effective care.Decision-making in resuscitation requires courage and leadership.Compassionate care benefits both the patient and their loved ones.Opioids play a significant role in managing pain in palliative care.Transitioning to palliative care is a necessary step in certain cases.Medical providers must educate themselves on end of life care.Patient autonomy should be respected in decision-making.Compassionate care can alleviate the emotional burden on medical providers.Chapters00:00 Introduction to End of Life Care in Combat02:34 The Challenges of Palliative Care in Military Settings09:57 Recognizing Non-Survivable Injuries19:08 Decision-Making in Resuscitation Efforts35:49 Transitioning to Palliative Care43:03 The Role of Opioids in Palliative Care53:18 Compassionate Care and Patient AutonomyThank you to Delta Development Team for in part, sponsoring this podcast.deltadevteam.comFor more content, go to www.prolongedfieldcare.orgConsider supporting us: patreon.com/ProlongedFieldCareCollective or www.lobocoffeeco.com/product-page/prolonged-field-care
Ben Westhoff is an award-winning investigative journalist whose best-selling 2019 book Fentanyl, Inc.: How Rogue Chemists Are Creating the Deadliest Wave of the Opioid Epidemic (Grove Press, 2019), was one of the first to take fentanyl seriously as both a social phenomenon and a national threat. Since its release, Westhoff has become a policy expert, advising top government officials on the fentanyl crisis, and continuing to follow the story on his Substack account. The author of two previous nonfiction books and numerous articles in outlets like the Atlantic, The Guardian, and the Wall Street Journal, Westhoff's fourth book, Little Brother: Love, Tragedy, and My Search for the Truth comes out this spring. Emily Dufton is the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017). A drug historian and writer, her second book, on the development of the opioid addiction medication industry, is under contract with the University of Chicago Press. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine
Ben Westhoff is an award-winning investigative journalist whose best-selling 2019 book Fentanyl, Inc.: How Rogue Chemists Are Creating the Deadliest Wave of the Opioid Epidemic (Grove Press, 2019), was one of the first to take fentanyl seriously as both a social phenomenon and a national threat. Since its release, Westhoff has become a policy expert, advising top government officials on the fentanyl crisis, and continuing to follow the story on his Substack account. The author of two previous nonfiction books and numerous articles in outlets like the Atlantic, The Guardian, and the Wall Street Journal, Westhoff's fourth book, Little Brother: Love, Tragedy, and My Search for the Truth comes out this spring. Emily Dufton is the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017). A drug historian and writer, her second book, on the development of the opioid addiction medication industry, is under contract with the University of Chicago Press. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine
Ben Westhoff is an award-winning investigative journalist whose best-selling 2019 book Fentanyl, Inc.: How Rogue Chemists Are Creating the Deadliest Wave of the Opioid Epidemic (Grove Press, 2019), was one of the first to take fentanyl seriously as both a social phenomenon and a national threat. Since its release, Westhoff has become a policy expert, advising top government officials on the fentanyl crisis, and continuing to follow the story on his Substack account. The author of two previous nonfiction books and numerous articles in outlets like the Atlantic, The Guardian, and the Wall Street Journal, Westhoff's fourth book, Little Brother: Love, Tragedy, and My Search for the Truth comes out this spring. Emily Dufton is the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017). A drug historian and writer, her second book, on the development of the opioid addiction medication industry, is under contract with the University of Chicago Press. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/public-policy
Ben Westhoff is an award-winning investigative journalist whose best-selling 2019 book Fentanyl, Inc.: How Rogue Chemists Are Creating the Deadliest Wave of the Opioid Epidemic (Grove Press, 2019), was one of the first to take fentanyl seriously as both a social phenomenon and a national threat. Since its release, Westhoff has become a policy expert, advising top government officials on the fentanyl crisis, and continuing to follow the story on his Substack account. The author of two previous nonfiction books and numerous articles in outlets like the Atlantic, The Guardian, and the Wall Street Journal, Westhoff's fourth book, Little Brother: Love, Tragedy, and My Search for the Truth comes out this spring. Emily Dufton is the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017). A drug historian and writer, her second book, on the development of the opioid addiction medication industry, is under contract with the University of Chicago Press. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science-technology-and-society
Ben Westhoff is an award-winning investigative journalist whose best-selling 2019 book Fentanyl, Inc.: How Rogue Chemists Are Creating the Deadliest Wave of the Opioid Epidemic (Grove Press, 2019), was one of the first to take fentanyl seriously as both a social phenomenon and a national threat. Since its release, Westhoff has become a policy expert, advising top government officials on the fentanyl crisis, and continuing to follow the story on his Substack account. The author of two previous nonfiction books and numerous articles in outlets like the Atlantic, The Guardian, and the Wall Street Journal, Westhoff's fourth book, Little Brother: Love, Tragedy, and My Search for the Truth comes out this spring. Emily Dufton is the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017). A drug historian and writer, her second book, on the development of the opioid addiction medication industry, is under contract with the University of Chicago Press. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/law
Dr. Charles LeBaron is a retired CDC scientist and the author of Greed to Do Good: The Untold Story of CDC's Disastrous War on Opioids. He talks with Steve about the ill-considered response to the opioid crisis and the tragic and preventable consequences of the CDC's 2016 guidelines. Restricting prescriptions without providing treatment (whether for pain relief or addiction) drove users to illicit opioids like fentanyl and a surge in overdose deaths.The conversation expands to systemic issues, including the corporate greed of Big Pharma, political exploitation of the crisis, and the punitive rather than rehabilitative approach to addiction. Steve and Charles highlight how austerity policies and privatization exacerbate the epidemic, disproportionately harming working class and marginalized communities. They criticize current political responses, such as RFK Jr.'s proposed cuts to addiction treatment programs in favor of ineffective "healing farms," as emblematic of a broader failure to address root causes. Both emphasize the need for compassionate, science-driven solutions over criminalization, underscoring how public health and social equity are inextricably linked. For more than twenty-eight years, Charles LeBaron worked as a medical epidemiologist at the Centers for Disease Control and Prevention (CDC). While there, he was the author of more than fifty scientific studies published in peer-reviewed journals, including first- or senior- author papers in the New England Journal of Medicine and the Journal of the American Medical Association.
Hello to all of our Poison Friends! As I am out of town this week, and the internet where I am is unstable (literally can't even FaceTime for more than 2 minutes lol), I decided to post a selection from our bonus episodes that we have over on the Patreon. I was able to get a new bonus episode out for our Patreon friends as well, since I was able to record that just before leaving, and I will be back at the end of the weekend so we will be back on track for regular episodes next week!**********************************************************Hello Poison Friends! I am back to bring you more toxins that are often causes of accidental poisoning. These include opioid medications, specifically the synthetic opioid fentanyl and the differences between clinical fentanyl and street/illegal versions. I also want to discuss the effects of pain meds and benzodiazepines on the body as well as the effects of mixing drugs with dangerous interactions. I had a specific celebrity's death in mind when describing such.Also, I wanted to discuss the old Tide Pod craze. If you remember, there was this social media challenge where young people were ingesting laundry detergent pods (specifically Tide Pods) and we need to talk about that as well as the dangers of leaving these out for children or those with cognitive issues to find and accidentally ingest.I am also including a whole collection of toys, accessories, or knickknacks that have proven dangerous or even deadly when found and ingested by children as well. Tiny magnets, button batteries, Aqua Dots, Orbeez, and toys from the 1950s that have lead to serious harm over the years. Some of these are still out there and require caution and supervision when used.As always, thank you to all of our listeners and supporters! Please feel free to leave a comment or send us a DM for any questions, suggestions, or just to say, "hi."Support us on Patreon:patreon.com/thepoisonersalmanacMerch-https://poisonersalmanac.com/Follow us on socials:The Poisoner's Almanac on IG-https://www.instagram.com/poisoners_almanac?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==YouTube-https://youtube.com/@thepoisonersalmanac-m5q?si=16JV_ZKhpGaLyM73Also, look for the Poisoner's Almanac TikTok- https://www.tiktok.com/@poisonersalmanacp?_t=ZT-8wdYQyXhKbm&_r=1Adam-https://www.tiktok.com/@studiesshow?is_from_webapp=1&sender_device=pcBecca-https://www.tiktok.com/@yobec0?is_from_webapp=1&sender_device=pc
Imagine a nation filled with men like Braxton McCoy. That's what America was. The rest of us are still reaping the benefits. (0:00) McCoy's Military Experience (36:24) McCoy's Intense Recovery Journey (1:00:35) The American Drug Epidemic (1:11:57) The Fake Environmentalists Secretly Trying to Destroy Nature (1:36:35) Food Security, the Housing Crisis, and Immigration Learn more about your ad choices. Visit megaphone.fm/adchoices
Join us this month as we talk with author Denise S. Robbins who has a new book out called The Unmapping; the Washington Writers Publishing House co-president Caroline Bock and Jona Colson, who are celebrating WWPH's 50th anniversary; author Rion Amilcar Scott who reads from his book, The World Does Not Require You; and indie lit legend Brian Allen Carr, author of Bad Foundations, Opioid, Indiana, Short Bus, and others. Denise S. Robbins is from Madison, Wisconsin, the city where she grew up and to which she returned after sixteen years of living and working in climate activism on the East Coast. In Madison, she lives with her husband in a yellow house circled by oaks and pines and two owls, and works as a consultant for several climate advocacy groups. She is a Pushcart Prize–nominated author whose stories have been published in literary journals including The Barcelona Review, Gulf Coast, and many more. Her debut novel, The Unmapping, was published in June 2025 from Mareas at Bindery Books. It is number 2 on People Magazine's top reads for the summer. The Unmapping is on order at DCPL. You can place a hold for when it arrives. Caroline Bock's short story collection, Carry Her Home, received the 2018 WWPH Fiction Prize. She is the author of two critically acclaimed young adult novels, LIE and Before My Eyes, from St. Martin's Press. In addition to her role as co-president, she is the prose editor at WWPH Writes, our bi-weekly literary journal, and the co-editor of our 2021 anthology This Is What America Looks Like Fiction and Poetry from D.C. Maryland, and Virginia. Her new novel, THE OTHER BEAUTIFUL PEOPLE. (Regal House Publishing) will be published on June 2, 2026.Jona Colson's poetry collection, Said Through Glass, won the 2018 Jean Feldman Poetry Prize from WWPH. He teaches English at Montgomery College. Notably, in addition to his role as co-president, he is the poetry editor of WWPH Writes, our bi-weekly literary journal, and the co-editor of This Is What America Looks Like: Poetry and Fiction from D.C., Maryland, and Virginia. He is also the translator for Aguas/Waters by Miguel Avero, our first work in translation, published in May 2024. Rion Amilcar Scott was born in Washington, D.C. and grew up in Silver Spring, Maryland. His parents are from Trinidad and came to the United States to study at Howard University. He graduated from George Mason University and teaches at The University of Maryland, College Park. His book Insurrections: Stories is available from DCPL2019:The World Doesn't Require You is available from DCPL Brian Allen Carr is an Aspen Words Finalist and two time Wonderland Book Award winner.His books include Opioid, Indiana, Bad Foundations and several others.He is from Texas and lives in Indiana.His novel Sip is available through DCPL.His novel Opioid, Indiana is available through DCPL.*********************************************************************************************************************************************Credits Dream Pop by HoliznaCC0 is licensed under a CC0 1.0 Universal License.https://freemusicarchive.org/music/holiznacc0/only-in-the-milky-way-part-3/dream-pop/Dark Ambient Music (Death And Forever) by TheBoseDeity is licensed under the Attribution NonCommercial 3.0 License.https://freesound.org/people/TheBoseDeity/sounds/395691/ Java Pop by Spires That in the Sunset Rise is licensed under a Attribution-Noncommercial-Share Alike 3.0 United States License.https://freemusicarchive.org/music/Spires_That_in_the_Sunset_Rise/Curse_the_Traced_Bird/Java_Pop/ Washington, DC by The Nighttime Adventure Society is licensed under a Attribution-NonCommercial-ShareAlike 3.0 International License.https://freemusicarchive.org/music/The_Nighttime_Adventure_Society/Chapter_One_The_First_Chapter/The_Nighttime_Adventure_Society_-_Chapter_One-_The_First_Chapter_-_01_Washington_DC/ kalas by Uncle Milk is licensed under a CC0 1.0 Universal License.https://freemusicarchive.org/music/microSong_Challenge/2015021275957958/kalas_1886/ Function! by junior85 is licensed under a CC0 1.0 Universal License.https://freemusicarchive.org/music/microSong_Challenge/2015021275957958/junior85_-_07_-_Function/ Re-Function! by junior85 is licensed under a CC0 1.0 Universal License.https://freemusicarchive.org/music/microSong_Challenge/2015021275957958/junior85_-_08_-_Re-Function/ Tipping Point by Ellennerv is licensed under a CC0 1.0 Universal License.https://freemusicarchive.org/music/microSong_Challenge/2015021275957958/Tipping_Point/ Pasty Cline “I'm Gonna Walk Some Dog” is in the public domain and is an official record of the United States Army. Armed Forces Radio Service. Arkansas Traveler by ecfike is licensed under a CC0 licensehttps://freesound.org/people/ecfike/sounds/135127/All audio comments are consented to by the The Labs Consent and Release form. Chorale by Andrew Christopher Smith is licensed under a Attribution-Noncommercial-Share Alike 3.0 United States License.Orbiting A Distant Planet by Quantum Jazz is licensed under a Attribution-ShareAlike 3.0 International License.Palimpseste by Iliaque is licensed under a Attribution-NonCommercial-ShareAlike 4.0 International License.SOLO ACOUSTIC GUITAR by Jason Shaw is licensed under a Attribution 3.0 United States License.Times square 1700.m4a by olofguf is licensed under CC0. https://freesound.org/people/olofgud/sounds/639703/
Discover the future of pain management on this episode of Atomic Anesthesia as we explore a major breakthrough: the FDA approval of suzetrigine, a first-in-class, nonopioid pain medication. Guided by cutting-edge research and expert editorial insight from Anesthesiology, we dig into how suzetrigine works—targeting the NaV1.8 sodium channel in peripheral nerves—and what this means for patients and providers facing acute pain. You'll hear about the pivotal NAVIGATE clinical trials, real-world patient experiences, and the medication's advantages over traditional opioids, including fewer side effects and no risk of addiction. Whether you're a healthcare professional, patient, or someone passionate about medical innovation, join us to learn how suzetrigine is poised to reshape pain relief and help bridge the gap left by the opioid crisis.References:Bertoch T, D'Aunno D, McCoun J, Solanki D, Taber L, Urban J, Oswald J, Swisher MW, Tian S, Miao X, Correll DJ, Negulescu P, Bozic C, Weiner SG. Suzetrigine, a Nonopioid Na V 1.8 Inhibitor for Treatment of Moderate-to-severe Acute Pain: Two Phase 3 Randomized Clinical Trials. Anesthesiology. 2025 Jun 1;142(6):1085-1099. doi: 10.1097/ALN.0000000000005460. Epub 2025 Mar 21. PMID: 40117446; PMCID: PMC12061372.Rathmell JP, Clark JD, Eisenach JC. Suzetrigine: First in a New Class of Nonopioid Analgesics for Acute Pain. Anesthesiology. 2025 Jun 1;142(6):989-991. doi: 10.1097/ALN.0000000000005465. Epub 2025 May 13. PMID: 40358331.
If opioids treat pain like a hammer, what medical researchers are looking for is something more like a delicate scalpel. Rivka Galchen holds a medical degree in addition to being a staff writer for The New Yorker, and she joins guest host Courtney Collins to discuss progress on developing alternative painkillers and why pain is so hard to manage in the first place. Her article is “The Radical Development of an Entirely New Painkiller.” Learn about your ad choices: dovetail.prx.org/ad-choices
In this episode, Jason, MDV, and Gabe get real about a growing epidemic: online sports betting. Is it just entertainment, or the next addiction crisis? The crew breaks down the alarming stats, the accessibility, and how gambling companies are pulling people in deeper than ever before—especially young men.They also talk mentorship, addiction, accountability, and why connection might be the antidote we're all overlooking.Topics include:[0:00] Wearing sunglasses to podcast and workout (power move or overkill?)[1:30] Are Russian assets listening to this podcast?[3:00] Why boys need mentors now more than ever[4:50] Sports betting is everywhere—CUT THE CRUTCH[8:00] Accessibility is the danger[9:45] These companies are building addictions by design[11:00] Who's responsible: the user or the system?[14:01] Gambling is a vicious and lonely cycle[15:58] Entire shows are built around betting lines[19:24] Will banning it even work?[21:55] How this affects your kids[23:00] Legalizing weed and the destruction of cities[27:30] You can ruin your life in one minute[29:00] Accountability vs. corporate manipulation[30:03] Addictive products are sold because they're addictive[32:20] One interaction can hook you for life[34:40] “The opposite of addiction is connection”[36:25] What really defines addiction?[44:05] CrossFit and addictive personalities (3 girls in one day??)[45:50] Dallas HYROX is already sold out[46:23] Epstein files… Jason spirals and MDV is not amused[53:24] You need something that centers you[56:35] Should you talk about politics and religion?[59:45] Jason signed up for Master Worlds—place your bets?
Check out friends at Reuther for all your paving needs with Nicolock https://www.reuthermaterial.com/BUY OUR MERCH HEREJoin the mail bag by leaving a voicemail at: 908-67-9999-3Our personal Instagrams:SoboChomikJimmyJordanWelcome back to The Garden State, the only NJ podcast that gives you all the news you need to know this week. Thanks for tuning in once again and for supporting the podcast. If you're enjoying the show, make sure to leave us a review! We love reading those!Follow us on all our socials to keep up to date with that and everything else happening. https://linktr.ee/thegardenstate
In this episode, we explore methadone maintenance therapy for opioid use disorder, covering dosing strategies, recent regulatory changes, and safety considerations. Why do so many patients fail on methadone despite its proven effectiveness, and how can proper dosing make the difference between recovery and relapse? Faculty: Smita Das, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Pharmacologic Management of Opioid Use Disorder Methadone for Managing OUD
60 MinutesPG-13Trey Garrison is an author and investigative reporterPete asked Trey to come on the show to talk about a book he wrote with his partner Richard McClure, "Opioids for the Masses: Big Pharma's War on Middle America and the White Working Class"Opioids for the Masses - Promo code "peteq"Pete and Thomas777 'At the Movies'Support Pete on His WebsitePete's PatreonPete's SubstackPete's SubscribestarPete's GUMROADPete's VenmoPete's Buy Me a CoffeePete on FacebookPete on TwitterBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-pete-quinones-show--6071361/support.