Podcasts about opioids

Today, we’re bringing you the best from the KUOW Newsroom… First, the Suquamish Tribe has unveiled a new social studies curriculum for neighboring public schools to use. It’s part of a statewide decades-long effort to teach Washington state students tribal history. Next, at least three research and development facilities in the Northwest are being considered for closure after US Forest Service restructuring. Scientists are working to continue long term research as they wait for answers. And finally, a group that’s been working for years to help address the opioid epidemic in Pierce County is being quietly shut down. We can only make Seattle Now because listeners support us. Tap here to make a gift and keep Seattle Now in your feed. Got questions about local news or story ideas to share? We want to hear from you! Email us at seattlenow@kuow.org, leave us a voicemail at (206) 616-6746 or leave us feedback online or on the KUOW App.See omnystudio.com/listener for privacy information.

On part 1 of opioids, I’ll discuss morphine, morphine equivalents, conversion, and hydrocodone. The pharmacokinetic differences will be important between opioids, as well as the dosage forms. I hope you enjoy this podcast episode and share it with your friends! Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources! NAPLEX Study Materials BCPS Study Materials BCACP Study Materials BCGP Study Materials BCMTMS Study Materials Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101

This episode examines the declining male labor force participation rate in America, which has fallen to its lowest level since 1948, with roughly one in three men no longer working or seeking work. While mainstream explanations point to manufacturing decline, an aging population, and the opioid crisis, host John Odermatt argues that a decade of DEI policies has systematically pushed men—especially white men—out of industries across corporate America, academia, media, and tech. Drawing on Jacob Savage's viral Compact Magazine article "The Lost Generation" and survey data from hiring managers themselves, the episode presents sector-by-sector evidence of documented hiring discrimination. Odermatt shares his own experience of being pushed out of corporate America and reframes the crisis not as a story of victimhood, but as a call for men to build income streams they control—through entrepreneurship, skilled trades, and commission-based work. The episode closes with a challenge to listeners: stop building your life on a foundation someone else can pull out from under you. Video Chapters 0:00 - The Hook: One in Three Men Are Not Working 1:10 - Welcome to Finding Freedom 2:09 - The Mainstream Explanation: Manufacturing, Opioids & Aging 3:03 - The DEI Explanation: What the Media Won't Say 3:32 - The Raw Numbers: Labor Force Participation Data 6:42 - Jacob Savage's "The Lost Generation" Article 8:18 - Sector-by-Sector: TV, Medicine, Academia, Tech & Media 11:22 - What Hiring Managers Admit: The Survey Data 13:45- The Fallout: Opioids, Video Games & Walking Away 16:07 - The Real Lesson: Build Your Own Escape & Closing Sources: The Lost Generation — Jacob Savage, Compact Magazine: compactmag.com/article/the-lost-generation What's Really Going On With Men and Work — American Institute for Boys and Men: aibm.org/research/whats-really-going-on-with-men-and-work-7-facts 1 in 6 Hiring Managers Have Been Told to Stop Hiring White Men — ResumeBuilder.com: resumebuilder.com/1-in-6-hiring-managers-have-been-told-to-stop-hiring-white-men DEI and the Lost Generation — Christopher Rufo: christopherrufo.com/p/dei-and-the-lost-generation Men's Falling Labor Force Participation Across Generations — San Francisco Fed: frbsf.org/research-and-insights/publications/economic-letter/2023/10/mens-falling-labor-force-participation-across-generations Schedule a 15 minute Gut Health Audit with John: https://calendar.app.google/B9fcGdSFjC5caTVu5 SUPPORT LIONS OF LIBERTY: Help keep this podcast going! We rely on listener support to continue bringing you content on freedom, political reform, and personal empowerment.  Support us on Patreon: https://patreon.com/lionsofliberty Support us on Locals: https://lionsofliberty.locals.com/ Subscribe, rate, and review wherever you listen – it makes a huge difference! Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode examines the declining male labor force participation rate in America, which has fallen to its lowest level since 1948, with roughly one in three men no longer working or seeking work. While mainstream explanations point to manufacturing decline, an aging population, and the opioid crisis, host John Odermatt argues that a decade of DEI policies has systematically pushed men—especially white men—out of industries across corporate America, academia, media, and tech. Drawing on Jacob Savage's viral Compact Magazine article "The Lost Generation" and survey data from hiring managers themselves, the episode presents sector-by-sector evidence of documented hiring discrimination. Odermatt shares his own experience of being pushed out of corporate America and reframes the crisis not as a story of victimhood, but as a call for men to build income streams they control—through entrepreneurship, skilled trades, and commission-based work. The episode closes with a challenge to listeners: stop building your life on a foundation someone else can pull out from under you. Video Chapters 0:00 - The Hook: One in Three Men Are Not Working 1:10 - Welcome to Finding Freedom 2:09 - The Mainstream Explanation: Manufacturing, Opioids & Aging 3:03 - The DEI Explanation: What the Media Won't Say 3:32 - The Raw Numbers: Labor Force Participation Data 6:42 - Jacob Savage's "The Lost Generation" Article 8:18 - Sector-by-Sector: TV, Medicine, Academia, Tech & Media 11:22 - What Hiring Managers Admit: The Survey Data 13:45- The Fallout: Opioids, Video Games & Walking Away 16:07 - The Real Lesson: Build Your Own Escape & Closing Sources: The Lost Generation — Jacob Savage, Compact Magazine: compactmag.com/article/the-lost-generation What's Really Going On With Men and Work — American Institute for Boys and Men: aibm.org/research/whats-really-going-on-with-men-and-work-7-facts 1 in 6 Hiring Managers Have Been Told to Stop Hiring White Men — ResumeBuilder.com: resumebuilder.com/1-in-6-hiring-managers-have-been-told-to-stop-hiring-white-men DEI and the Lost Generation — Christopher Rufo: christopherrufo.com/p/dei-and-the-lost-generation Men's Falling Labor Force Participation Across Generations — San Francisco Fed: frbsf.org/research-and-insights/publications/economic-letter/2023/10/mens-falling-labor-force-participation-across-generations Schedule a 15 minute Gut Health Audit with John: https://calendar.app.google/B9fcGdSFjC5caTVu5 SUPPORT LIONS OF LIBERTY: Help keep this podcast going! We rely on listener support to continue bringing you content on freedom, political reform, and personal empowerment.  Support us on Patreon: https://patreon.com/lionsofliberty Support us on Locals: https://lionsofliberty.locals.com/ Subscribe, rate, and review wherever you listen – it makes a huge difference! Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode examines the declining male labor force participation rate in America, which has fallen to its lowest level since 1948, with roughly one in three men no longer working or seeking work. While mainstream explanations point to manufacturing decline, an aging population, and the opioid crisis, host John Odermatt argues that a decade of DEI policies has systematically pushed men—especially white men—out of industries across corporate America, academia, media, and tech. Drawing on Jacob Savage's viral Compact Magazine article "The Lost Generation" and survey data from hiring managers themselves, the episode presents sector-by-sector evidence of documented hiring discrimination. Odermatt shares his own experience of being pushed out of corporate America and reframes the crisis not as a story of victimhood, but as a call for men to build income streams they control—through entrepreneurship, skilled trades, and commission-based work. The episode closes with a challenge to listeners: stop building your life on a foundation someone else can pull out from under you. Video Chapters 0:00 - The Hook: One in Three Men Are Not Working 1:10 - Welcome to Finding Freedom 2:09 - The Mainstream Explanation: Manufacturing, Opioids & Aging 3:03 - The DEI Explanation: What the Media Won't Say 3:32 - The Raw Numbers: Labor Force Participation Data 6:42 - Jacob Savage's "The Lost Generation" Article 8:18 - Sector-by-Sector: TV, Medicine, Academia, Tech & Media 11:22 - What Hiring Managers Admit: The Survey Data 13:45- The Fallout: Opioids, Video Games & Walking Away 16:07 - The Real Lesson: Build Your Own Escape & Closing Sources: The Lost Generation — Jacob Savage, Compact Magazine: compactmag.com/article/the-lost-generation What's Really Going On With Men and Work — American Institute for Boys and Men: aibm.org/research/whats-really-going-on-with-men-and-work-7-facts 1 in 6 Hiring Managers Have Been Told to Stop Hiring White Men — ResumeBuilder.com: resumebuilder.com/1-in-6-hiring-managers-have-been-told-to-stop-hiring-white-men DEI and the Lost Generation — Christopher Rufo: christopherrufo.com/p/dei-and-the-lost-generation Men's Falling Labor Force Participation Across Generations — San Francisco Fed: frbsf.org/research-and-insights/publications/economic-letter/2023/10/mens-falling-labor-force-participation-across-generations Schedule a 15 minute Gut Health Audit with John: https://calendar.app.google/B9fcGdSFjC5caTVu5 SUPPORT LIONS OF LIBERTY: Help keep this podcast going! We rely on listener support to continue bringing you content on freedom, political reform, and personal empowerment.  Support us on Patreon: https://patreon.com/lionsofliberty Support us on Locals: https://lionsofliberty.locals.com/ Subscribe, rate, and review wherever you listen – it makes a huge difference!Become a supporter of this podcast: https://www.spreaker.com/podcast/heartland-newsfeed-radio-network--2904397/support.

To listen to the rest of this episode, search for Last Day wherever you listen to podcasts. When Nadia Bowers's sister Sasha died of fentanyl overdose in 2015, Nadia was seven months pregnant with her first child and had gotten married just six weeks earlier. Suddenly she had to ask herself: how do I go on after the worst thing that's ever happened to me? In this episode, Nadia tells Stephanie how writing her new memoir, Dear Dealer, helped her process her rage, grief, and the anxiety of new motherhood while navigating this crippling loss. Pick up a copy of ⁠Dear Dealer⁠, available wherever books are sold or listen to the audiobook, narrated by Nadia. Order Steph's book Last Day: How to Stop Losing Our Loved Ones to the Opioid Crisis at ⁠https://bit.ly/LastDayBook⁠, and the audiobook at ⁠https://bit.ly/3RW4WtF⁠, or wherever books and audiobooks are sold. Learn more about your ad choices. Visit megaphone.fm/adchoices

To listen to the rest of this episode, search for Last Day wherever you listen to podcasts. When Nadia Bowers's sister Sasha died of fentanyl overdose in 2015, Nadia was seven months pregnant with her first child and had gotten married just six weeks earlier. Suddenly she had to ask herself: how do I go on after the worst thing that's ever happened to me? In this episode, Nadia tells Stephanie how writing her new memoir, Dear Dealer, helped her process her rage, grief, and the anxiety of new motherhood while navigating this crippling loss. Pick up a copy of ⁠Dear Dealer⁠, available wherever books are sold or listen to the audiobook, narrated by Nadia. Order Steph's book Last Day: How to Stop Losing Our Loved Ones to the Opioid Crisis at ⁠https://bit.ly/LastDayBook⁠, and the audiobook at ⁠https://bit.ly/3RW4WtF⁠, or wherever books and audiobooks are sold. Learn more about your ad choices. Visit megaphone.fm/adchoices

To listen to the rest of this episode, search for Last Day wherever you listen to podcasts. When Nadia Bowers's sister Sasha died of fentanyl overdose in 2015, Nadia was seven months pregnant with her first child and had gotten married just six weeks earlier. Suddenly she had to ask herself: how do I go on after the worst thing that's ever happened to me? In this episode, Nadia tells Stephanie how writing her new memoir, Dear Dealer, helped her process her rage, grief, and the anxiety of new motherhood while navigating this crippling loss. Pick up a copy of Dear Dealer, available wherever books are sold or listen to the audiobook, narrated by Nadia. Order Steph's book Last Day: How to Stop Losing Our Loved Ones to the Opioid Crisis at https://bit.ly/LastDayBook, and the audiobook at https://bit.ly/3RW4WtF, or wherever books and audiobooks are sold. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hayden Panettiere died suddenly in Greenville, South Carolina at 36. TMZ reports that Narcan, the nasal spray used to reverse an opioid overdose, was found in the apartment. Dr. Drew is joined by his Celebrity Rehab costars – addiction counselor Bob Forrest and certified chemical dependency counselor Shelly Sprague-Foster – to discuss Hayden's opioid addiction, postpartum depression, and what we know about her tragic and sudden death. Panettiere told People in 2022 that she had been in a cycle of self-destruction, and wrote in her memoir that a doctor warned she would be dead within 5 years if she did not stop drinking. She said she was given pills as a teenager before red carpet appearances, developed an opioid dependency after being prescribed painkillers for an injury, and experienced withdrawal severe enough to send her to a liver specialist. Page Six reports, through a friend, that she had severe back problems in the months before her death. NBC News reports her ex-boyfriend was at the scene when she died. Also on today's show: Dr. James Thorp, a maternal fetal medicine specialist with more than 40 years in practice who was fired by SSM Health after speaking out about COVID-19 vaccines in pregnancy. He says federal officials and the New England Journal of Medicine knew about adverse pregnancy outcomes in early 2021 and hid them. Bob Forrest is a musician, author, and addiction counselor. He served as a counselor on VH1's Celebrity Rehab, works with DNA4Addiction, and authored Running with Monsters: A Memoir. Follow at https://x.com/bobforrestmusic Shelly Sprague-Foster is a Certified Chemical Dependency Counselor–Certified Addiction Specialist who has worked with individuals affected by substance use disorders since 1997. She co-founded Hollywood Recovery Services with Bob Forrest and now directs We Care Outpatient. Find more at https://wecareinla.com Dr. James Thorp is an obstetrician-gynecologist and maternal fetal medicine specialist who served in the SSM Health System in Saint Louis, Missouri. He earned his medical degree from Wayne State University School of Medicine and has practiced for more than 40 years. Follow at https://x.com/jathorpmfm 「 SUPPORT OUR SPONSORS 」 • BIOPRO - BioPro+® is a natural formula of growth factors and peptides that support how you look, feel & perform. Learn more at ⁠⁠https://drdrew.com/biopro⁠⁠ • FATTY15 – The future of essential fatty acids is here! Strengthen your cells against age-related breakdown with Fatty15. 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To listen to the rest of this episode, search for Last Day wherever you listen to podcasts. When Nadia Bowers's sister Sasha died of fentanyl overdose in 2015, Nadia was seven months pregnant with her first child and had gotten married just six weeks earlier. Suddenly she had to ask herself: how do I go on after the worst thing that's ever happened to me? In this episode, Nadia tells Stephanie how writing her new memoir, Dear Dealer, helped her process her rage, grief, and the anxiety of new motherhood while navigating this crippling loss. Pick up a copy of ⁠Dear Dealer⁠, available wherever books are sold or listen to the audiobook, narrated by Nadia. Order Steph's book Last Day: How to Stop Losing Our Loved Ones to the Opioid Crisis at ⁠https://bit.ly/LastDayBook⁠, and the audiobook at ⁠https://bit.ly/3RW4WtF⁠, or wherever books and audiobooks are sold. Learn more about your ad choices. Visit megaphone.fm/adchoices

To listen to the rest of this episode, search for Last Day wherever you listen to podcasts. When Nadia Bowers's sister Sasha died of fentanyl overdose in 2015, Nadia was seven months pregnant with her first child and had gotten married just six weeks earlier. Suddenly she had to ask herself: how do I go on after the worst thing that's ever happened to me? In this episode, Nadia tells Stephanie how writing her new memoir, Dear Dealer, helped her process her rage, grief, and the anxiety of new motherhood while navigating this crippling loss. Pick up a copy of ⁠Dear Dealer⁠, available wherever books are sold or listen to the audiobook, narrated by Nadia. Order Steph's book Last Day: How to Stop Losing Our Loved Ones to the Opioid Crisis at ⁠https://bit.ly/LastDayBook⁠, and the audiobook at ⁠https://bit.ly/3RW4WtF⁠, or wherever books and audiobooks are sold. Learn more about your ad choices. Visit megaphone.fm/adchoices

I'm insanely impressed by Stephanie Wittels Wachs, not just because she's the co-founder and CEO of Lemonada Media, an award-winning podcast network with a mission to "make life suck less,” but because of her ability to use humor and wit to get through loss. She lost her brother, writer-producer-comedian Harris Wittels, to the opioid crisis and has now written multiple books on the topic. This raw exploration of grief is also a manual for anyone else struggling with how to help an addicted loved one. Our conversation ranged from entrepreneurship and what it takes to start something new to her profound struggles in the aftermath of sibling loss. Hosted on Acast. See acast.com/privacy for more information.

To listen to the rest of this episode, search for Last Day wherever you listen to podcasts. When Nadia Bowers's sister Sasha died of fentanyl overdose in 2015, Nadia was seven months pregnant with her first child and had gotten married just six weeks earlier. Suddenly she had to ask herself: how do I go on after the worst thing that's ever happened to me? In this episode, Nadia tells Stephanie how writing her new memoir, Dear Dealer, helped her process her rage, grief, and the anxiety of new motherhood while navigating this crippling loss. Pick up a copy of ⁠Dear Dealer⁠, available wherever books are sold or listen to the audiobook, narrated by Nadia. Order Steph's book Last Day: How to Stop Losing Our Loved Ones to the Opioid Crisis at ⁠https://bit.ly/LastDayBook⁠, and the audiobook at ⁠https://bit.ly/3RW4WtF⁠, or wherever books and audiobooks are sold. Learn more about your ad choices. Visit megaphone.fm/adchoices

To listen to the rest of this episode, search for Last Day wherever you listen to podcasts. When Nadia Bowers's sister Sasha died of fentanyl overdose in 2015, Nadia was seven months pregnant with her first child and had gotten married just six weeks earlier. Suddenly she had to ask herself: how do I go on after the worst thing that's ever happened to me? In this episode, Nadia tells Stephanie how writing her new memoir, Dear Dealer, helped her process her rage, grief, and the anxiety of new motherhood while navigating this crippling loss. Pick up a copy of ⁠Dear Dealer⁠, available wherever books are sold or listen to the audiobook, narrated by Nadia. Order Steph's book Last Day: How to Stop Losing Our Loved Ones to the Opioid Crisis at ⁠https://bit.ly/LastDayBook⁠, and the audiobook at ⁠https://bit.ly/3RW4WtF⁠, or wherever books and audiobooks are sold. Learn more about your ad choices. Visit megaphone.fm/adchoices

To listen to the rest of this episode, search for Last Day wherever you listen to podcasts. When Nadia Bowers's sister Sasha died of fentanyl overdose in 2015, Nadia was seven months pregnant with her first child and had gotten married just six weeks earlier. Suddenly she had to ask herself: how do I go on after the worst thing that's ever happened to me? In this episode, Nadia tells Stephanie how writing her new memoir, Dear Dealer, helped her process her rage, grief, and the anxiety of new motherhood while navigating this crippling loss. Pick up a copy of ⁠Dear Dealer⁠, available wherever books are sold or listen to the audiobook, narrated by Nadia. Order Steph's book Last Day: How to Stop Losing Our Loved Ones to the Opioid Crisis at ⁠https://bit.ly/LastDayBook⁠, and the audiobook at ⁠https://bit.ly/3RW4WtF⁠, or wherever books and audiobooks are sold. Learn more about your ad choices. Visit megaphone.fm/adchoices

To listen to the rest of this episode, search for Last Day wherever you listen to podcasts. When Nadia Bowers's sister Sasha died of fentanyl overdose in 2015, Nadia was seven months pregnant with her first child and had gotten married just six weeks earlier. Suddenly she had to ask herself: how do I go on after the worst thing that's ever happened to me? In this episode, Nadia tells Stephanie how writing her new memoir, Dear Dealer, helped her process her rage, grief, and the anxiety of new motherhood while navigating this crippling loss. Pick up a copy of ⁠Dear Dealer⁠, available wherever books are sold or listen to the audiobook, narrated by Nadia. Order Steph's book Last Day: How to Stop Losing Our Loved Ones to the Opioid Crisis at ⁠https://bit.ly/LastDayBook⁠, and the audiobook at ⁠https://bit.ly/3RW4WtF⁠, or wherever books and audiobooks are sold.

To listen to the rest of this episode, search for Last Day wherever you listen to podcasts. When Nadia Bowers's sister Sasha died of fentanyl overdose in 2015, Nadia was seven months pregnant with her first child and had gotten married just six weeks earlier. Suddenly she had to ask herself: how do I go on after the worst thing that's ever happened to me? In this episode, Nadia tells Stephanie how writing her new memoir, Dear Dealer, helped her process her rage, grief, and the anxiety of new motherhood while navigating this crippling loss. Pick up a copy of ⁠Dear Dealer⁠, available wherever books are sold or listen to the audiobook, narrated by Nadia. Order Steph's book Last Day: How to Stop Losing Our Loved Ones to the Opioid Crisis at ⁠https://bit.ly/LastDayBook⁠, and the audiobook at ⁠https://bit.ly/3RW4WtF⁠, or wherever books and audiobooks are sold. Learn more about your ad choices. Visit megaphone.fm/adchoices

To listen to the rest of this episode, search for Last Day wherever you listen to podcasts. When Nadia Bowers's sister Sasha died of fentanyl overdose in 2015, Nadia was seven months pregnant with her first child and had gotten married just six weeks earlier. Suddenly she had to ask herself: how do I go on after the worst thing that's ever happened to me? In this episode, Nadia tells Stephanie how writing her new memoir, Dear Dealer, helped her process her rage, grief, and the anxiety of new motherhood while navigating this crippling loss. Pick up a copy of ⁠Dear Dealer⁠, available wherever books are sold or listen to the audiobook, narrated by Nadia. Order Steph's book Last Day: How to Stop Losing Our Loved Ones to the Opioid Crisis at ⁠https://bit.ly/LastDayBook⁠, and the audiobook at ⁠https://bit.ly/3RW4WtF⁠, or wherever books and audiobooks are sold. Learn more about your ad choices. Visit megaphone.fm/adchoices

Most friendships start because you have something in common: work, hobbies, fashion, books, sense of humor. But not all friendships are formed because of something wholesome in common. Sometimes, you share an experience so life-changing that you are drawn to each other. That is how, nine years ago, Nora and Steph Wittels Wachs became friends. Steph lost her brother, Harris, to an opioid overdose. Grievers can always find common ground: losing someone changes you. If you have lived this before, you'll find it feeling familiar. If you haven't, consider yourself lucky. Watching a family member suffer from opioid addiction is crushing. Losing them is debilitating. Steph and I want to talk to you if you have been affected by the opioid crisis. If you have something to share, give us a call or a text: ☎️‪(612) 568-4441‬. Watch us on YouTube here! Get this episode ad-free here! Listen to Geoffrey's album on Spotify and Apple! You can buy Nora's books on Bookshop or Amazon, or wherever you buy books. Nora is on IG, TikTok, Facebook and LinkedIn. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, David Turner, MD, FAAP, discusses the American Board of Pediatrics' proposed changes to pediatric fellowships. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Mario Morales, PhD, about bullying, suicidality and opioid-specific risks in U.S. adolescents. For resources go to aap.org/podcast.

Millions of Americans take the herbal supplement kratom for everything from energy to pain relief to quitting opioids. But it has also been linked to growing addiction rates and fatal overdoses. WSJ's Sumathi Reddy explains the regulatory battles playing out across the country as some officials consider bans. Jessica Mendoza hosts.   Further Listening: - Is the High Over for Hemp Drinks? - Peptides Are Everywhere. Businesses Are Cashing In. Sign up for WSJ's free What's News newsletter. Learn more about your ad choices. Visit megaphone.fm/adchoices

On the August 14 edition: Nearly two-thirds of the state's third graders need help reading; The man behind Georgia's largest Ponzi scheme is sentenced; And two Beluga whales rescued from a defunct Canadian aquarium have arrived in Atlanta. 

Addiction affects millions of people, yet stigma and misunderstanding often prevent people from seeking help. In this episode of Health Matters, host Courtney Allison speaks with Dr. Jonathan Avery, an addiction psychiatrist at NewYork-Presbyterian and Weill Cornell Medicine, about the realities of addiction and recovery. Dr. Avery explains that addiction is more than a problem of willpower. Drawing on research and clinical experience, he discusses how genetics, mental health, trauma, social factors, and brain chemistry all play a role in the development of substance use disorders and behavioral addictions. The conversation examines how addictive behaviors, from alcohol use and opioid dependence to gambling and social media use, affect the brain's reward system and why quitting can be so difficult. Dr. Avery also shares how newer treatments, including medications and emerging research on GLP-1 medications, are changing the landscape of addiction care. Finally, Dr. Avery discusses the importance of reducing stigma, building supportive communities, and recognizing that recovery is possible. He offers practical advice for people who may be struggling themselves as well as guidance for supporting loved ones with compassion and understanding. Chapters 00:00 – What Is Addiction? Why addiction is more than a substance, the role of trauma and mental health, and what happens in the brain 05:05 – Gambling, Screens, and Modern Addictions How behavioral addictions affect the brain and why smartphones have changed the landscape 09:00 – Treatment, Recovery, and New Hope Available therapies, medications, emerging GLP-1 research, and why most people do get better 11:30 – Breaking Stigma and Supporting Recovery Why connection matters, how addiction overlaps with mental health, and ways to support loved ones Key Topics Covered Addiction Recovery Substance use disorders Alcohol use disorder Opioid addiction Fentanyl epidemic Behavioral addictions Gambling addiction Social media addiction Gaming addiction Nicotine and vaping Dopamine and reward pathways Withdrawal Mental health and addiction Trauma and addiction Addiction stigma Recovery support Community and connection Addiction treatment Medication-assisted treatment GLP-1 medications Self-medication hypothesis Depression and addiction Anxiety and addiction Addiction psychiatry Key Takeaway Addiction is a complex health condition influenced by brain biology, mental health, life experiences, and environment, not simply a lack of willpower. While quitting can be challenging, effective treatments, supportive communities, and growing understanding of addiction are helping more people achieve lasting recovery. Reaching out for help is often the first and most important step.   Bio: Jonathan Avery, M.D., is an addiction psychiatrist at NewYork-Presbyterian/Weill Cornell Medical Center and vice chair of addiction psychiatry, a professor of clinical psychiatry, and the Stephen P. Tobin and Dr. Arnold M. Cooper Professor in Consultation-Liaison Psychiatry at Weill Cornell Medicine. He is the program director for the addiction psychiatry fellowship at NewYork-Presbyterian and Weill Cornell Medicine. He also serves as the medical director of the NBA's Anti-Drug Program. Dr. Avery graduated from the New York University School of Medicine and completed his psychiatry residency at New York-Presbyterian/Weill Cornell Medical Center. During residency, he was selected as a Group for the Advancement of Psychiatry Fellow, served as co-chief resident in his final year, and received several awards for his clinical and academic work. He then completed a fellowship in addiction psychiatry at the New York University School of Medicine before joining the faculty at Weill Cornell Medicine. Dr. Avery has published widely in addiction psychiatry, with work spanning clinician attitudes toward patients with addiction, treatment approaches for substance use disorders, and the intersection of mental illness and addiction. He is the founder of the NewYork-Presbyterian and Weill Cornell Medicine Program for Substance Use and Stigma of Addiction, and his research on stigma has been supported by multiple national grants and awards. He has served on the editorial board for the DSM-5 Clinical Cases book and is the editor and author of more than 10 books, including Co-occurring Mental Illness and Substance Use Disorders: A Guide to Diagnosis and Treatment and The Stigma of Addiction: An Essential Guide. His forthcoming book, Thriving with Addiction: A New Roadmap for Lasting Recovery and Health (Prometheus Books, 2026), explores how recovery can become a pathway to improved brain and physical health. Dr. Avery is also the host of the Thriving with Addiction podcast, where he interviews leading researchers, clinicians, athletes and public figures about addiction, recovery and behavior change. He has received numerous awards for his clinical and academic work, including the American Board of Psychiatry and Neurology Faculty Innovation in Education Award and the Outstanding Faculty Member Award from the New York County Psychiatric Society.

BUFFALO, NY — August 12, 2026 — A new #research paper was #published in Volume 18 of Aging on July 27, 2026, titled “Transcriptomic aging clock analysis identifies key genes in opioid dependence.” The study was led by first author Hai Duc Nguyen from the Division of Microbiology, Tulane National Biomedical Research Center, Tulane University. The corresponding author is Woong-Ki Kim, who is affiliated with the Division of Microbiology, Tulane National Biomedical Research Center, Tulane University, and the Department of Microbiology and Immunology at Tulane University School of Medicine. Opioid dependence is a chronic and relapsing condition associated with substantial health and societal burdens. Chronic opioid exposure can affect neuronal signaling, immune function, metabolism, and other biological processes, yet the molecular mechanisms underlying dependence remain incompletely understood. Increasing evidence also suggests that substance use disorders may be associated with molecular changes related to aging, raising questions about how chronic opioid exposure interacts with age-dependent processes in the brain. To investigate these relationships, the researchers conducted an in silico study integrating three complementary approaches: RNA sequencing-based transcriptomic profiling, transcriptomic aging-clock modeling, and analysis of previously published genome-wide association studies (GWAS). The transcriptomic analysis used a publicly available brain RNA-seq dataset containing 42 samples—21 healthy controls and 21 individuals with opioid dependence—while the genetic analysis incorporated findings from six independent GWAS. Full press release - https://www.aging-us.com/news-room/transcriptomic-aging-clock-reveals-age-related-molecular-patterns-in-opioid-dependence DOI - https://doi.org/10.18632/aging.206405 Corresponding author - Woong-Ki Kim - wkim6@tulane.edu Abstract video - https://www.youtube.com/watch?v=7VwU0mFGkbg Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206405 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, opioids, GWAS, transcriptomic clock To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

My guests today are Abigail Lee and Johanna Bennett, two Doctor of Nursing Practice graduate students at the University of New England who focused their DNP project on perioperative use of IV methadone. Abigail Lee attended Southern Maine Community College and transferred to the University of Southern Maine to study nursing. She worked at Maine Medical Center in the Cardiothoracic Intensive Care Unit. She intends to head down to North Carolina to work as a CRNA. Johanna Bennett went to Saint Anselm College. She started her career in healthcare in the Medical/COVID ICU as a new graduate nurse and worked there for three years before starting CRNA school at the University of New England. Jo will be joining our team at Maine Medical Center to work as a CRNA. This episode is on the longer side, so here's your TL:DL, too-long; didn't listen summary of perioperative IV methadone – the opioid-spairing opioid. Standard short-acting pure mu-agonists—like fentanyl, hydromorphone, and morphine—often leave our patients trapped in a roller coaster of ‘peaks and valleys,’ leading to oversedation, unexpected pain spikes, and high total opioid consumption in the PACU. In this episode, we explore why methadone is uniquely positioned as the ‘opioid-sparing opioid.’ Beyond its strong -receptor agonism, methadone boasts NMDA receptor antagonism and serotonin/norepinephrine reuptake inhibition, targeting pain at multiple pathways to blunt central sensitization and wind-up phenomenon. Key Clinical Takeaways from the Literature: The Effective Dose: An ideal single dose on induction is 0.2 to 0.25 mg/kg ideal body weight (or roughly 10-20 mgIV). Underdosing (

Deaths from opioid overdoses hit record highs in 2021 and 2022, and are now on the decline. But there is still much work to be done. Mike Vasquez has devoted his life to confronting the opioid crisis on a mental, physical, and spiritual front and he joins us with more.

WSJM Afternoon News for 08-10-26See omnystudio.com/listener for privacy information.

D.C.'s 2027 fiscal-year blueprint reflects a debate playing out around the U.S.: whether opioid settlement money should be used to free up taxpayer dollars by paying for existing responsibilities instead of new programs.

Understanding opioid selection in the OR is all about recognizing pharmacokinetics and how they align with surgical needs and patient factors, rather than focusing solely on receptor effects. This episode explores the five opioids you use most—morphine, fentanyl, sufentanil, remifentanil, and hydromorphone—and offers a framework for choosing optimally among them.Opioid receptor mechanisms and their clinical outcomesLipid solubility's role in opioid kineticsPharmacokinetics of morphine, fentanyl, sufentanil, remifentanil, and hydromorphoneManaging side effects like respiratory depression and opioid-induced hyperalgesiaGuidelines for opioid selection based on case specifics and patient renal functionResourcesAtomic Anesthesia Platform — In-depth lessons and quizzes on each opioid.FREE RESOURCE FOR THIS EPISODE:GPCR Cheat Sheet — G-protein coupled receptors decoded for anesthesia. Head to atomicanesthesia.com/freebies/gpcr-cheat-sheet to grab it free.MORE FREE STUDY RESOURCES:SEE/NCE Study Plan — A structured, week-by-week plan to pass your boardsNon-Opioid Pharmacology Cheat Sheet — Every non-opioid analgesic you need to know, on one pageMalignant Hyperthermia Reference Guide — Recognize MH fast. Treat it faster — one-page referenceWANT THE FULL PLATFORM?Atomic Anesthesia is the all-in-one study platform built specifically for SRNAs — lessons, quizzes, flashcards, and more. Start your free trial at atomicanesthesia.com.Mentioned in this episode:

Season 5, episode 2 of the Just Us podcast places an emphasis on the treatment of substance use disorder in adolescents and young adults. Psychiatrist Leeallie Carter and family medicine physician Blake Fagan discuss the interactions between human biology, adverse childhood experiences, and substance use during this developmental period. The nuances of and barriers to adolescent SUD treatment are discussed in detail. Listen in to learn more!Resources: Substance Use Disorder Treatment Resources for Youth, Young Adults, and Families: https://opa.hhs.gov/adolescent-health/substance-use-adolescence Resources to Address the Opioid Epidemic: https://www.aap.org/en/patient-care/substance-use-and-prevention/resources-to-address-the-opioid-epidemic/ Substance Use Disorder Treatment Resources for Youth, Young Adults, and Families: https://www.samhsa.gov/substance-use/treatment/youth-and-families  We would love your feedback on our podcast!  Please take our listener survey to provide your comments.Music credit: "Carefree" Kevin MacLeod (incompetech.com)  Licensed under Creative Commons: By Attribution 4.0 Licensehttp://creativecommons.org/licenses/by/4.0/ Please provide feedback here:https://redcap.mahec.net/redcap/surveys/?s=XTM8T3RPNK 

In this episode, Dr Elle Wadsworth talks to Dr Louise Marryat, a senior research fellow at the University of Glasgow, Scotland. The interview covers Louise's systematic review on prenatal opioid exposure, and health, social and educational outcomes for school-aged children.The motivation behind Louise's systematic review [00:50]The current evidence surrounding prenatal opioid exposure and early outcomes [02:13]What Louise defined as prenatal opioid exposure in her review [03:08] The limitation of small sample sizes in the included studies [04:08]The methods of the review [04:55]The key findings of the review [08:20]The implications of the findings on Scottish health policy [12:38]The take home messages for researchers and clinicians [15:48]About Elle Wadsworth: Elle is an academic fellow with the Society for the Study of Addiction. She is based at the University of Bath with the Addiction and Mental Health Group and her research interests include drug policy, cannabis legalisation, and public health. Elle holds a voluntary role at The Loop, a non-profit service provider of drug checking in the UK. About Louise Marryat: Louise is a UK Research and Innovation (UKRI) Future Leaders Fellow and Senior Research Fellow at the University of Glasgow. A sociologist by training, she holds a PhD in Psychological Medicine and has dedicated her career to understanding the social, environmental, and psychological factors that shape health and wellbeing across the life course. She currently leads the UK Opioids in Pregnancy Study (https://opioidsinpregnancy.gla.ac.uk/), exploring the impacts of opioid use and treatment during pregnancy on mothers and children. Her research focuses on reducing health inequalities and improving outcomes for children, families, and communities experiencing disadvantage through evidence-based policy and practice.Declarations of interest: None Original article: Prenatal opioid exposure, and health, social and educational outcomes for school-aged children: A systematic review https://doi.org/10.1111/add.70510 The opinions expressed in this podcast reflect the views of the host and interviewees and do not necessarily represent the opinions or official positions of the SSA or Addiction journal.The SSA does not endorse or guarantee the accuracy of the information in external sources or links and accepts no responsibility or liability for any consequences arising from the use of such information. Hosted on Acast. See acast.com/privacy for more information.

Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. In this summer sizzler, we have three new pieces of research for clinicians in general practice. First, do antihistamines help with managing atopic eczema, or do they do more harm than good? Does which one we use matter? Second, exploring the pain relief achieved by opioids in the short and long term. Are there new lessons to be learned? Third, for an alternative way of managing chronic MSK pain, could self-directed CBT be the solution?ReferencesBMJ Antihistamines and eczemaUK data on use of antihistamines for eczemaEczema Care OnlineBJGP Opioid effects on pain over timeJAMA Self-directed CBT for chronic MSK painPodcast on chronic pain with Rangan Chatterjee and Howard Schubinerwww.nbmedical.com/podcast

Send us Fan MailHow can hospice and palliative care become more person-centered while also becoming more reliable?In Part One of this Anatomy of Leadership conversation, host Chris Comeaux sits down with Kelly McCutcheon Adams, Senior Director at the Institute for Healthcare Improvement (IHI), and Margherita Labson, President and CEO of McLabson Consultation & Education Services, to explore the groundbreaking 4 M's Framework and its growing impact on hospice and palliative care. Originally developed through the Age-Friendly Health Systems Initiative, the 4 M's—What Matters, Medication, Mentation, and Mobility—provide a practical, evidence-based framework for helping healthcare teams consistently deliver individualized care that aligns with each patient's goals while improving reliability across the care continuum. During this conversation, you'll discover:Why the 4 M's are a framework—not another quality measureHow "What Matters" transforms goal-concordant hospice careWhy reliability and individualized care are not mutually exclusiveHow medication decisions should be guided by patient goals—not habitsWhat hospice leaders can learn from the science of quality improvementWhether you're a hospice executive, palliative care clinician, healthcare leader, or quality improvement professional, this episode offers practical insights for building care systems that are both compassionate and consistently excellent. Don't miss Part Two, where we continue the discussion by exploring the remaining 4Ms and practical strategies for implementing this framework within hospice organizations.Chapters00:00 Introduction00:22 Meet Kelly McCutcheon Adams & Margherita Labson04:14 What is the 4Ms Framework?06:58 How IHI is Bringing the 4Ms to Hospice Care09:43 The Mission of the Institute for Healthcare Improvement (IHI)11:46 Why the 4Ms Work Across Every Care Setting15:17 Framework vs. Traditional Quality Measures17:24 What "What Matters" Really Means in Hospice21:08 Reliable Systems for Individualized Care26:57 Medication Decisions Guided by Patient Goals32:12 Hospice, Opioids, and Changing the Conversation34:37 Coming Up in Part Two

How can hospice and palliative care become more person-centered while also becoming more reliable?In Part One of this Anatomy of Leadership conversation, host Chris Comeaux sits down with Kelly McCutcheon Adams, Senior Director at the Institute for Healthcare Improvement (IHI), and Margherita Labson, President and CEO of McLabson Consultation & Education Services, to explore the groundbreaking 4 M's Framework and its growing impact on hospice and palliative care. Originally developed through the Age-Friendly Health Systems Initiative, the 4 M's—What Matters, Medication, Mentation, and Mobility—provide a practical, evidence-based framework for helping healthcare teams consistently deliver individualized care that aligns with each patient's goals while improving reliability across the care continuum. During this conversation, you'll discover:Why the 4 M's are a framework—not another quality measureHow "What Matters" transforms goal-concordant hospice careWhy reliability and individualized care are not mutually exclusiveHow medication decisions should be guided by patient goals—not habitsWhat hospice leaders can learn from the science of quality improvementWhether you're a hospice executive, palliative care clinician, healthcare leader, or quality improvement professional, this episode offers practical insights for building care systems that are both compassionate and consistently excellent. Don't miss Part Two, where we continue the discussion by exploring the remaining 4Ms and practical strategies for implementing this framework within hospice organizations.Chapters00:00 Introduction00:22 Meet Kelly McCutcheon Adams & Margherita Labson04:14 What is the 4Ms Framework?06:58 How IHI is Bringing the 4Ms to Hospice Care09:43 The Mission of the Institute for Healthcare Improvement (IHI)11:46 Why the 4Ms Work Across Every Care Setting15:17 Framework vs. Traditional Quality Measures17:24 What "What Matters" Really Means in Hospice21:08 Reliable Systems for Individualized Care26:57 Medication Decisions Guided by Patient Goals32:12 Hospice, Opioids, and Changing the Conversation34:37 Coming Up in Part Two

This episode was planned to meet the educational needs of critical care pharmacists by increasing their awareness of the prevalence of opioid use disorder, common challenges encountered in managing pain control and sedation in patients with opioid use disorder, and how to implement best practices in this patient population. CE for this episode expires 2 years after the date it was originally published. The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.

Millions of people in the U.S. have chronic pain that's unresponsive to medical interventions. But there are new and comprehensive ways of treating pain. We explore how emotions, stress, sleep, and diet impact pain, a new option for easing labor pain, and emerging research that could reduce the addictive properties of opioids. We often think of pain as a physical ailment — but newer research shows that pain has as much to do with our brains as it does our bodies. We talk with pain researcher and psychologist Rachel Zoffness about how emotions shape — and construct — our experience of pain, and how identifying the unique biopsychosocial factors contributing to pain can ultimately help patients overcome it. Her new book is "Tell Me Where It Hurts: The New Science of Pain and How to Heal." Giving birth is one of the most painful things many people will experience — which is why a majority of expectant mothers choose epidurals, IV opioids, or both to manage their pain. But recently, another option has been making its way into the delivery room— nitrous oxide, also known as laughing gas. Reporter Andrew Stelzer explains how N02  stacks up against its competitors, and why a growing number hospitals in the U.S. are offering it as an option. Opioids work well on all kinds of pain — but, as the last few decades have shown, they also pose a severe risk of addiction. We talk with neuroscientist and addiction researcher Anjali Rajadhyaksha about a recent discovery that could make opioids safer.

Host: Coach Guest: Cassidy Lujan Air date: Jul 30, 2026

Dr. Aileen Marty, Infectious Disease Specialist and Professor at Florida International University, joins Bob Sirott to talk about the latest health news. Dr. Marty explains what an opioid is and shares details about the FDA approved non-opioid Journavx that targets moderate to severe acute pain.

In this episode of Beyond The Abstract, Dr. Joao De Aquino joins the show to talk about his new article The Role of Childhood Trauma in Chronic Pain and Substance Use Among Individuals Receiving Methadone Treatment for Opioid Use Disorder featured in the May/June issue of the Journal of Addiction Medicine.   Article Link: The Role of Childhood Trauma in Chronic Pain and Substance Use Among Individuals Receiving Methadone Treatment for Opioid Use Disorder

Come with Brandon down the rabbit hole and learn how the opioid crisis got so bad and who was at fault.

Richard Dion, PharmD, joins Over the Counter to discuss the emerging prominence of opioid stewardship in health systems' pain management programs and how the necessary role of pharmacists is making a true difference for patients.

Singer Melissa Etheridge talks about touring with Wynonna Judd and the inspiration behind her new album “Rise.”

Come with Brandon down the rabbit hole and learn how the opioid crisis got so bad and who was at fault

In this episode of The President's Daily Brief: The battle for the Strait of Hormuz is entering a dangerous new chapter. We examine why the Trump administration has once again shifted its strategy against Iran—and what that tells us about where the war is headed. The remnants of Russia's Wagner mercenary force have reportedly traded the battlefield for the drug trade. We look at allegations that former Wagner fighters are operating a growing opioid empire in one of Africa's most lawless regions. The Trump administration launches a new campaign against the International Criminal Court, with Secretary of State Marco Rubio vowing to curb the tribunal's influence and shield Americans from its jurisdiction. In today's Back of the Brief, Congress moves to honor the late Senator Lindsey Graham by reviving one of his signature priorities: a sweeping new package of sanctions targeting Russia. To listen to the show ad-free, become a premium member of The President's Daily Brief by visiting https://PDBPremium.com. Please remember to subscribe if you enjoyed this episode of The President's Daily Brief.  YouTube: youtube.com/@presidentsdailybrief Lifepro Fitness: Discover how to beat puffiness with the Lifepro Waver Vibration Plate—and use code PDB at https://lifeprofitness.com for $20 off plus free shipping! Mars Men: For a limited time, our listeners get 50% off FOR LIFE, Free Shipping, AND 3 Free Gifts at Mars Men at https://Mengotomars.com Ridge: One thing to pack, five ways to power! Get 10% off @Ridge with code PDB at https://www.Ridge.com/PDB#Ridgepod Learn more about your ad choices. Visit megaphone.fm/adchoices

I sat down with Dr. Andrea Sereda at the Sherbourne Health Centre on the east side of downtown Toronto, an area of the city sometimes known for its challenges with drug abuse. Who is Dr. Andrea Sereda? She is a family physician who practices street outreach medicine and provides care through the London InterCommunity Health Centre in London, Ontario. She works with the emergency safer supply substitution program, prescribing hydromorphone, an opioid used by injection drug users to reduce the risk of contaminated street drugs. Wait! What? Yes, on the face of it, Dr. Andrea Sereda gives drugs to drug users but there is a lot more to the story. We are going right to the front lines of the opioid epidemic which, even before the end of this conversation, will take 10 lives in North America alone. (To illustrate the issue more deeply, 8,048 Americans died of opioid related drug overdoses in 1999. What about now? Well, the number was approximately 70,000 drug overdose deaths last year.) It will take ingenuity, creativity, and passion to address this issue. As you'll hear, Dr. Andrea Sereda offers all three in spades. Her views are often provocative, sometimes controversial, and she will argue that drugs should be decriminalized and why we should indeed give drugs to drug users. What about the challenges to these ideas? The critics? The controversies? We get into that, too. And we are fortunate enough to use Andrea's three most formative books as a launchpad into this conversation. I am so grateful to Dr. Andrea Sereda for sharing so much of her life, her journey, and her practice with all of us. I find her and her work incredibly challenging, intriguing, and inspiring. I hope you do, too.

At the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists (ANZCA) and Faculty of Pain Medicine (FPM) held in Auckland, New Zealand, Kate Leslie and Andy Cumpstey interview Neel Desai about non-opioid multi-modal analgesia, especially the use of paracetamol/NSAID combinations for minor surgery. Dr Neel Desai is a Consultant Anaesthetist at Guys and St Thomas's Hospital, London, UK. He is supported by AFT Pharmaceuticals. -- The 2026 International Practicum on Cardiopulmonary Exercise Testing will be held at the Balmer Lawn Hotel in Brockenhurst, UK, from September 16th to 18th this year. It is organised by iPOETTS , the international perioperative testing and training society. Come and join us at this premier educational event designed for clinicians, scientists, and healthcare professionals interested in sport, exercise, and perioperative medicine. This is an International Perioperative Testing and Training Society accredited event so when you attend you can get your iPOETTS accreditation, showing that you are a practitioner who has reached a high, standardized level of competence in performing and interpreting Cardiopulmonary Exercise Testing (CPET) for patients preparing for major surgery. Go now to http://www.ebpom.org

Fifty years ago the U.S. government classified it alongside heroin: no accepted medical use, high potential for abuse, illegal in most of the world. The peer-reviewed data now coming out of Johns Hopkins, Imperial College, and Nature tells a different story, one that has some of the most credentialled neuroscientists alive rethinking how the brain heals. In this episode, Louisa breaks down exactly what psilocybin does to your neurons, why it works where antidepressants stall for decades, and where the research is heading right now. She walks through the default mode network, the self-referential system that turns rigid and hyperactive in depression, and the 2024 Nature study that described psilocybin's effect on it as "massive" disruption. You'll hear how a single dose drove a measurable jump in dendritic spine density within 24 hours, why psilocin binds the TRKB receptor 300 times more strongly than any conventional antidepressant, and how Robin Carhart-Harris's head-to-head trial against escitalopram produced more than double the remission rate. Then she turns to addiction, where psilocybin-assisted therapy reached an 80% smoking abstinence rate at six months in the Johns Hopkins pilot, more than double the best medication available today. She covers the risks the drug-war narrative leaves out, the hard contraindications around psychosis and cardiac history, the April 2026 executive order that accelerated federal review, and why the quality of the subjective experience, measured on the Mystical Experience Questionnaire, may matter to the outcome as much as the molecule itself. You'll also hear about the desynchronization event and what fills the space when the network goes offline, BDNF and how it stacks up against high-intensity exercise, the alcohol and opioid data, HPPD, Australia's 2023 reclassification, Oregon and Colorado's state access frameworks, and why set and setting may be active ingredients in how the treatment works. Fifty years ago the U.S. government classified it alongside heroin: no accepted medical use, high potential for abuse, illegal in most of the world. The peer-reviewed data now coming out of Johns Hopkins, Imperial College, and Nature tells a different story, one that has some of the most credentialled neuroscientists alive rethinking how the brain heals. In this episode, Louisa breaks down exactly what psilocybin does to your neurons, why it works where antidepressants stall for decades, and where the research is heading right now. She walks through the default mode network, the self-referential system that turns rigid and hyperactive in depression, and the 2024 Nature study that described psilocybin's effect on it as "massive" disruption. You'll hear how a single dose drove a measurable jump in dendritic spine density within 24 hours, why psilocin binds the TRKB receptor 300 times more strongly than any conventional antidepressant, and how Robin Carhart-Harris's head-to-head trial against escitalopram produced more than double the remission rate. Then she turns to addiction, where psilocybin-assisted therapy reached an 80% smoking abstinence rate at six months in the Johns Hopkins pilot, more than double the best medication available today. She covers the risks the drug-war narrative leaves out, the hard contraindications around psychosis and cardiac history, the April 2026 executive order that accelerated federal review, and why the quality of the subjective experience, measured on the Mystical Experience Questionnaire, may matter to the outcome as much as the molecule itself. You'll also hear about the desynchronization event and what fills the space when the network goes offline, BDNF and how it stacks up against high-intensity exercise, the alcohol and opioid data, HPPD, Australia's 2023 reclassification, Oregon and Colorado's state access frameworks, and why set and setting may be active ingredients in how the treatment works. *Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: * https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ *TOPICS DISCUSSED* 00:00 Intro: A Schedule I Drug That's Making Neuroscientists Rethink the Brain 00:39 The Default Mode Network and Your Sense of Self 02:49 How Depression Locks the Brain Into a Rigid Loop 03:23 Where SSRIs Stop Short of the Problem 04:44 The Brain Imaging Data: "Massive" DMN Disruption and Reorganization 06:58 Confirming It in Drug-Naive Brains 08:04 The Rewiring: How Psilocybin Changes Neural Architecture 08:35 Dendritic Spines and Synaptic Density 09:39 How Chronic Stress Shrinks Your Neural Connections 10:16 One Dose, More Connections in 24 Hours (Neuron 2021) 11:02 BDNF, TRKB, and a Signal 300x Stronger Than Antidepressants 13:21 Psilocybin vs the Gold-Standard SSRI 14:37 Double the Remission Rate: The Numbers That Matter 15:53 Side Effects, Durability, and Treatment-Resistant Depression 16:39 The Addiction Breaker: 80% Smoking Abstinence at Six Months 17:36 Alcohol, Opioids, and the Shared Architecture of Addiction 19:10 The Dark Side: Real Risks and Hard Contraindications 22:35 The Policy Earthquake: Executive Orders and FDA Breakthrough Status 24:37 Why It Actually Works: Set, Setting, and the Mystical Experience 26:57 Bringing It All Together _______ *Thank you to our sponsors* Function Health: https://functionhealth.com/LouisaNicola Use code NEURO25 for a $25 credit BASED Bodyworks: https://basedbodyworks.com/ Use code NEURO for 20% off (plus a free toiletry bag with any set) BioOptimizers: https://www.bioptimizers.com/neuro Use code NEURO for 15% off IQBAR: Text NEURO to 64000 for 20% off all IQBAR products plus FREE shipping (Message and data rates may apply) Learn more about your ad choices. 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My friend Ryan Rogers returns to the podcast for our third conversation. He's an addictions counselor in Texas, host of Reality Therapy, and now the author of two books — The Woke Mind and his new release, The Carpenter's Recovery, a Christian guide to 12-step recovery. We start with what's being called "gas station heroin": a chemical called 7-OH, extracted from kratom, that's roughly thirteen times stronger than morphine and sold legally next to the 5-Hour Energy drinks at the checkout counter. Ryan walks me through how legal loopholes have produced a generation of accidental addicts, including church kids and high-conscientiousness adults who'd never touch illegal drugs. I share my own "little old lady" story — how my elderly mom was given a 10mg THC gummy by her stoner massage therapist — as a warning to anyone navigating this new landscape with vulnerable elders. From there we go into cannabis-induced psychosis, cannabis use hyperemesis disorder, fentanyl displacing heroin, and what's actually working in addiction treatment. Ryan explains why he wrote a Christian recovery book and why naming Jesus in AA meetings still gets people shut down. We close on the state of the therapy field: woke ideology, AI psychosis, the rise of niche experts over licensed therapists, and why "live your truth, king" is the worst possible response to a client telling you they're about to relapse.Follow Reality Therapy podcast | Follow Ryan on X @ryanmcrogers[00:00:00] Start[00:02:06] Gas Station Heroin: What Is 7-OH?[00:05:55] Kava, Feel Free, and Designer Drugs[00:11:25] How 7-OH Hits the Opioid System[00:14:30] The Little Old Lady THC Gummy Story[00:25:30] Methadone vs. Suboxone for Detox[00:35:56] The Carpenter's Recovery: A Christian Approach[00:40:32] Why AA Pushes Back on Christianity[00:48:15] Reality Therapy and the State of the Field[00:53:42] AI Psychosis and the Future of Therapy[00:58:40] Tough Love and "Live Your Truth, King"[01:04:30] Honoring Who Teenagers Are BecomingROGD REPAIR Course + Community gives concerned parents instant access to over 120 lessons providing the psychological insights and communication tools you need to get through to your kid. Now featuring 24/7 personalized AI support implementing the tools with RepairBot! Use code SOMETHERAPIST2026 to take 50% off your first month.PODCOURSES: use code SOMETHERAPIST at LisaMustard.com/PodCoursesPRODUCTION: Looking for your own podcast producer? Visit PodsByNick.com and mention my podcast for 20% off your initial services.MUSIC: Thanks to Joey Pecoraro for our song, “Half Awake,” used with gratitude & permission.ALL OTHER LINKS HERE. To support this show, please leave a rating & review on Apple, Spotify, or wherever you get your podcasts. Subscribe, like, comment & share via my YouTube channel. Or recommend this to a friend!Learn more about Do No Harm.Take $200 off your EightSleep Pod Pro Cover with code SOMETHERAPIST at EightSleep.com.Take 20% off all superfood beverages with code SOMETHERAPIST at Organifi.Check out my shop for book recommendations + wellness products.Show notes & transcript provided with the help of SwellAI.Special thanks to Joey Pecoraro for our theme song, “Half Awake,” used with gratitude and permission.Watch NO WAY BACK: The Reality of Gender-Affirming Care (our medical ethics documentary, formerly known as Affirmation Generation). Stream the film or purchase a DVD. Use code SOMETHERAPIST to take 20% off your order. Follow us on X @2022affirmation or Instagram at @affirmationgeneration.Have a question for me? Looking to go deeper and discuss these ideas with other listeners? Join my Locals community! Members get to ask questions I will respond to in exclusive, members-only livestreams, post questions for upcoming guests to answer, plus other perks TBD. ★ Support this podcast on Patreon ★

On this podcast episode, I cover commonly used medications for opioid use disorder. Buprenorphine, methadone, and naltrexone are all potential options in OUD. I’ll discuss the pharmacology of each medication and the most common practice pearls that will show up in practice and on your board exams. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources! NAPLEX Study Materials BCPS Study Materials BCACP Study Materials BCGP Study Materials BCMTMS Study Materials Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101

In this wild, unpredictable hour, host Walter Sterling and UFO expert Dave Scott dive deep into the government's alleged UFO crash retrieval programs, top-secret 25-story underground bunkers, and why private corporations might be hiding alien bodies to dodge Freedom of Information Act requests. Walter brings you the "real" news. Cap it all off with bizarre listener UFO sightings and a caller who masterfully connects opioids, Obama, and COVID cremations into one glorious conspiracy theory. Buckle up and embrace the other side! Learn more about your ad choices. Visit megaphone.fm/adchoices