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Forecasters have said the snow across New South Wales and parts of Victoria is a “significant event” not seen for 16 years.Bureau of Meteorology meteorologist Gabrielle Woodhouse told news.com.au that snow had reached to far northern parts of New South Wales while on the ski resorts of Perisher and Thredbo in the far south as much as half a metre of snow had descended in the last 24 hours.“We don't often see really widespread snowfall across the New South Wales ranges all the way up to the Queensland border, And likewise, we don't take falling down to such low levels so it is quite significant,” she said on Thursday afternoon.Temperatures across the state have plummeted with Sydney still hovering around 9C at what should be the hottest part of the day. If the mercury remains below 11C in the city it will be the coldest day for 25 years.“Today, it's going to be significantly cold across the state so temperatures are generally going to be at least 10 degrees below average and quite a few places will approach or exceed the lowest maximums temperature record,” Ms Woodhouse said.The snow was likely to continue today on higher ground and will replaced by fierce winds on Friday.Pictures have streamed in from across NSW of the winter wonderland conditions.The forecast for Armidale includes snow and the snowfalls have already been reported in the Northern Tablelands town of Guyra.Snow has also been reported in Orange.Further north in Queensland the apparent temperature dropped to a freezing -5.6C at Wellcamp Airport near Toowoomba.Oakey, an agricultural centre and home to the Army Aviation Centre, shivered through an apparent temperature of -4.2C.The bureau says a low pressure system over central New South Wales will enhance the cool to cold westerly flow over southern Queensland today. It is predicting snow or sleet at times about the higher terrain on the Granite Belt.The cold snap is due to a pool of cold air direct from Antarctica.The bureau has warned that temperatures could plunge 10 degrees below average over the next day or so.Up to 20mm of snow could fall over areas that may only get a dusting once every few years.“This major winter storm will intensify across southeast Australia during Wednesday,” Sky News Weather senior meteorologist Tom Saunders said.“New South Wales will be the centre of this winter storm in terms of the snowfall over the next couple of days.”Mr Saunders said today should be the coldest day in decades for central and northern regions.text by Andrew Backhouse and Benedict Brook, news.com.au
Na edição nº 7 (T4) da rúbrica FAZ-TE AO LIVRO, o aluno do 11C da EB/S de Infias, José Lisboa, sugere o livro A RAPARIGA DO LAGO de Charlie Donlea. 18-11-2020
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.29.354696v1?rss=1 Authors: Obokata, N., Seki, C., Hirata, T., Maeda, J., Ishii, H., Nagai, Y., Matsumura, T., Takakuwa, M., Fukuda, H., Minamimoto, T., Kawamura, K., Zhang, M.-R., Nakajima, T., Saijo, T., Higuchi, M. Abstract: Purpose: Phosphodiesterase (PDE) 7 is a potential therapeutic target for neurological and inflammatory diseases, while in-vivo visualization of PDE7 has not been successful. In this study, we aimed to develop [11C]MTP38 as a novel positron emission tomography (PET) ligand for PDE7. Methods: [11C]MTP38 was radiosynthesized by 11C-cyanation of a bromo precursor with [11C]HCN. PET scans of rat and rhesus monkey brains and in-vitro autoradiography of brain sections derived from these species were conducted with [11C]MTP38. In monkeys, dynamic PET data were analyzed with an arterial input function to calculate the total distribution volume (VT). The non-displaceable binding potential (BPND) in the striatum was also determined by a reference tissue model with the cerebellar reference. Finally, striatal occupancy of PDE7 by an inhibitor was calculated in monkeys according to changes in BPND. Results: [11C]MTP38 was synthesized with radiochemical purity [≥] 99.4% and molar activity of 38.6 {+/-} 12.6 GBq/mol. Autoradiography revealed high radioactivity in the striatum and its reduction by non-radiolabeled ligands, in contrast with unaltered autoradiographic signals in other regions. In-vivo PET after radioligand injection to rats and monkeys demonstrated that radioactivity was rapidly distributed to the brain and intensely accumulated in the striatum relative to the cerebellum. Correspondingly, VT values estimated in the monkey striatum and cerebellum were 3.59 and 2.69 mL/cm3, respectively. The cerebellar VT value was unchanged by pretreatment with unlabeled MTP38. Striatal BPND was reduced in a dose-dependent manner after pretreatment with MTP-X, a PDE7 inhibitor. Relationships between the PDE7 occupancy by MTP-X and plasma MTP-X concentration could be described by Hill's sigmoidal function. Conclusion: We have provided the first successful preclinical demonstration of in-vivo PDE7 imaging with a specific PET radioligand. [11C]MTP38 is a feasible radioligand to evaluate PDE7 in the brain and is currently applied to a first-in-human PET study. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.18.302943v1?rss=1 Authors: Garcia Guerra, S., Spadoni, A., Mitchell, J., Strigo, I. A. Abstract: Molecular mechanisms of the interaction between pain and reward associated with pain relief processes in the human brain are still incompletely understood. This is partially due to the invasive nature of the available techniques to visualize and measure metabolic activity. Positron Emission Tomography (PET) radioligand studies using radioactive substances are still the only available modality to date that allows for the investigation of the molecular mechanisms in the human brain. For pain and reward studies, the most commonly studied PET radiotracers are [11C]-carfentanil (CFN) and [11C]- or [18F]-diprenorphine (DPN), which bind to opioid receptors, and [11C]-raclopride (RAC) and [18F]-fallypride (FAL) tracers, which bind to dopamine receptors. The current meta-analysis looks at 15 pain-related studies using opioid radioligands and 8 studies using dopamine radioligands in an effort to consolidate the available data into the most likely activated regions. Our primary goal was to identify regions of shared opioid/dopamine neurotransmission during pain-related experiences. SDM analysis of previously published voxel coordinate data showed that opioidergic activations were strongest in the bilateral caudate, thalamus, right putamen, cingulate gyrus, midbrain, inferior frontal gyrus, and left superior temporal gyrus. The dopaminergic studies showed that the bilateral caudate, thalamus, right putamen, cingulate gyrus, and left putamen had the highest activations. We were able to see a clear overlap between opioid and dopamine activations in a majority of the regions during pain-related processing, though there were some unique areas of dopaminergic activation such as the left putamen. Regions unique to opioidergic activation include the midbrain, inferior frontal gyrus, and left superior temporal gyrus. By investigating the regions of dopaminergic and opioidergic activation, we can potentially provide more targeted treatment to these sets of receptors in patients with pain conditions. These findings could eventually assist in the development of more targeted medication in order to help treat pain conditions and simultaneously prevent physical dependency. Copy rights belong to original authors. Visit the link for more info
On September 29, 1986 in Las Vegas, Nevada, Cotton Kelly aka James Thiede was gunned down by 18-year-old Troy Kell and 17-year-old Billy Merritt, when asked by 15-year-old Sandy Shaw to rough him up. Kell would go on to murder Lonnie Blackmon in prison, and the security camera footage of the incident went on to form the basis of the film ‘Gladiator Days: Anatomy of a Prison Murder.’Thanks to Daniel Gleason, and for more information visit https://www.gofundme.com/f/sandy-shaw-wrongful-convictionMusic:We Talk of Dreamswww.purple-planet.comSources:https://corrections.utah.gov/images/deathrow.pdfLost Innocence (George Knapp interview) https://www.youtube.com/watch?v=A3Eeck3kLAE&t=8sGladiator Days: Anatomy of a Prison Murder https://www.youtube.com/watch?v=FcnzWn6RKowhttps://www.youtube.com/watch?v=sA6zFFKGFMUEdmonton Journal (AP). October 9, 1986, p. 54 (F2).Hazelton-Standard-Speaker (AP). April 25, 1979. p. 13.The Salt Lake Tribune (AP). October 26, 1984. p. 12A.Philadelphia Daily News (AP). September 26, 1984. p. 18.C.G. Wallace. Reno Gazette-Journal (AP). May 23, 2003. p. 11C.Reno Gazette-Journal. October 9, 1988. p. 1D.Reno Gazette-Journal. October 10, 1991. P. 1B.Las Vegas Review Journal. ‘Show and Tell Killer Paroled’. September 11, 2007. https://www.reviewjournal.com/news/show-and-tell-killer-paroled/Las Vegas Sun. April 30, 1999. ‘Veteran deputy DA may have tried his last case.’ https://lasvegassun.com/news/1999/apr/30/veteran-deputy-da-may-have-tried-his-last-murder-c/Elko Daily Free Press (AP). ‘You killer considered for parole after 10 years.’ June 27, 1996. https://www.newspapers.com/image/477315076/?terms=Sandy%2BShawJack Sheehan, Las Vegas Sun. ‘After 21 year on hold, she’s ready for life.’ March 17, 2008. https://lasvegassun.com/news/2008/mar/17/after-21-years-hold-shes-ready-life/Jeff German, March 20, 2008. ‘A little late, witness in show and tell figure’s trial recants his testimony.’ https://lasvegassun.com/news/2008/mar/20/little-late-witness-show-and-tell-figures-trial-re/L. Zane Pinnock. ‘10 Facts About The Most Dangerous Man In Nevada’. January 17, 2020. https://www.ranker.com/list/patrick-mckenna-most-dangerous-man-in-nevada/l-zane-pinnockNate Carlisle, Salt Lake CIty Tribune. From one side of glass, condemned killer marries. December 10, 2010. https://archive.sltrib.com/article.php?id=50850117&itype=CMSIDSteven Dark, Salt Lake CIty Weekly. ‘Prison Made: From convicted murderer to in-house prison reformer, Paul Payne's not done fighting for his life.’ https://www.cityweekly.net/utah/prison-made/Content?oid=2287123Ben Winslow. ‘Federal court hears case over delays in executing Utah white supremacist killer’. November 28, 2018. https://www.fox13now.com/2018/11/28/federal-court-hears-case-over-delays-in-executing-utah-white-supremacist-killer/Ben Winslow. ‘Court dismisses appeal involving Utah white supremacist death row inmate’. June 5, 2019. https://www.fox13now.com/2019/06/05/utah-death-row-inmates-appeal-dismissed/?utm_source=related_2Prison Legal News. ‘$25,000 Award to Utah Muslim Prisoner Attacked by Death Row Prisoner Following 9/11.’ September, 2009. p. 38. https://www.prisonlegalnews.org/news/2009/sep/15/25000-award-to-utah-muslim-prisoner-attacked-by-death-row-prisoner-following-911/David Kiharalas, Las Vegas Review-Journal. ‘Man gets life sentence in sexual assault, kidnapping.’ December 12, 2008. https://www.reviewjournal.com/news/man-gets-life-sentence-in-sexual-assault-kidnapping/?clearUserState=true
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.01.127027v1?rss=1 Authors: Freiburghaus, T., Svensson, J. E., Matheson, G. J., Plaven-Sigray, P., Lundberg, J., Farde, L., Cervenka, S. Abstract: Dopamine D2 receptors (D2-R) in extrastriatal brain regions are of high interest for research in a wide range of psychiatric and neurologic disorders. Pharmacological competition studies and test-retest experiments have shown high validity and reliability of the positron emission tomography (PET) radioligand [11C]FLB 457 for D2-R quantification in extrastriatal brain regions. However, this radioligand is not available at most research centres. Instead, the medium affinity radioligand [11C]raclopride, which has been extensively validated for quantification of D2-R in the high-density region striatum, has been applied also in studies on extrastriatal D2-R. Recently, the validity of this approach has been questioned by observations of low occupancy of [11C]raclopride in extrastriatal regions in a pharmacological competition study. Here, we utilise a data set of 16 healthy control subjects examined with both [11C]raclopride and [11C]FLB 457 to assess the correlation in binding potential (BPND) in extrastriatal brain regions. BPND was quantified using the simplified reference tissue model with cerebellum as reference region. The rank order of mean regional BPND values were similar for both radioligands, and corresponded to previously reported data, both post-mortem and using PET. Nevertheless, weak to moderate within-subject correlations were observed between [11C]raclopride and [11C]FLB 457 BPND extrastriatally (Pearsons R: 0.30 - 0.56), in contrast to very strong correlations between repeated [11C]FLB 457 measurements (Pearsons R: 0.82 - 0.98). These results are likely related to low signal to noise ratio of [11C]raclopride in extrastriatal brain regions, and further strengthen the recommendation that extrastriatal D2-R measures obtained with [11C]raclopride should be interpreted with caution. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.05.20.104349v1?rss=1 Authors: Sun, L., Tang, J., Liljenback, H., Honkaniem, A., Virta, J., Isojarvi, J., Karjalainen, T., Kantonen, T., Nuutila, P., Hietala, J., Kaasinen, V., Kalliokoski, K., Hirvonen, J., Scheinin, H., Helin, S., Eerola, K., Savontaus, E., Yatkin, E., Rinne, J. O., Roivainen, A., Nummenmaa, L. Abstract: Seasonal rhythms influence mood and sociability. The mu-opioid receptor (MOR) system modulates a multitude of seasonally varying socioemotional functions, but seasonal variation in the MOR system remains elusive. We used positron emission tomography (PET) imaging with [11C]carfentanil, a high affinity MOR radioligand, to repeatedly measure in vivo brain receptor availability of adult rats (n=12) under seasonal photoperiodic simulation. Seasonal effects of human MOR availability were addressed retrospectively using a large historical dataset (n=204) of [11C]carfentanil scans. In rats daylength had a causal, inverted U-shaped functional relationship with MOR availability. Similar pattern of changes was also found in human brains. We conclude that brain MOR availability in both rats and humans shows significant seasonal variation that aligns with expected seasonal variation in mood. Copy rights belong to original authors. Visit the link for more info
11C النجم تفسیر 62-43
Coach Jesus, Jean-Paul Sartre and Josiah Royce "But I am like a green olive tree in the house of God; I trust in the mercy of God for ever and ever" (Psalm 25). Chad Harbach in his novel The Art of Fielding writes about Schwarz a stocky, strong young football and baseball player. He feels determined not to become one of those "ex-jocks" who considered high school and college the best days of their lives.1 For this reason, despite everyone's expectations, he resists going into coaching. The author describes his state of mind. "He already knew how to coach. All you had to do was to look at each of your players and ask yourself: What story does this guy wish that someone would tell about himself? And then you told the guy that story. You told it with a hint of doom. You included his flaws. You emphasized the obstacles that could prevent him from succeeding... People love to suffer as long as the suffering made sense. Everybody suffered. The key was to choose your form of suffering... A good coach made you suffer in a way that suited you." The Puritan preacher Jonathan Edwards' (1703-1758) perhaps second most famous sermon was called "The Excellency of Christ."2 Edwards describes "the admirable conjunction" of opposites in Jesus who is both the Lion of Judah and the Lamb of God. Christ sits in power at the right hand of the Almighty, above galaxies, at the origin of all things, and yet is so humble that he would be our friend. Nowhere does Edwards describe Jesus as a coach. But this is one way that the mystical Christ becomes present in our life. Christ offers stories that can become our own, that will change how we experience everything. My life has been transformed by Jesus and continues to be. This story of Martha and Mary has sunk deep into my consciousness and profoundly affects how I understand the world and how I act in it. Martha invites Jesus over. Mary breaks social taboos by sitting at the feet of Jesus with the male disciples. Martha bitterly insists that Jesus should order Mary to work like her. And Coach Jesus says, "Martha, Martha, you are anxious and troubled about many things; one thing is needful. Mary has chosen the good portion, which shall not be taken away from her" (Lk. 10). At various stages I have asked friends what they think of this story and often they have strong feelings. Many times they feel frustrated and take offense at Jesus. They identify with Martha. They point out that someone has to do these tasks. They want her work to be rewarded. The relationship between all siblings is complicated and many of us simply identify more closely with Martha. Often Bible stories simply do not affirm our sense of fairness.3 Stories like Mary and Martha, the Prodigal Son, the Parable of the Day Laborers, Jacob and Essau, Cain and Abel unsettle us. These are stories about people who did not work hard, who should not have been rewarded, but somehow received more than they deserved. In our secular time stories still are what provide orientation in our life. Because we deeply believe in meritocracy, the Bible's lack of respect for our notions of fairness is hard for us. Being deeply attached to fairness may be for us a sign that we lack faith in God. In life context is everything. That is true for the Bible also. This morning we have only part of the story. The episode begins when a lawyer comes to Jesus wondering how to inherit eternal life. Jesus asks what scripture says and the lawyer correctly answers that there are two great commandments, to love the Lord your God with all of your heart and soul and mind. The second commandment is like unto it, love your neighbor as yourself.4 The lawyer asks, "who is my neighbor?" and Jesus answers with the story of the Good Samaritan. It illustrates that loving our neighbor means transcending our identity, and reaching across boundaries to care for another person. This story of Martha and Mary on the other hand is an answer to the question of how we love God. For me, after a lifetime of study, each year it becomes less about fairness and more about learning to listen. Paying attention is how we love God. This morning I want to point out three brief implications of this kind of listening from two philosophers and a theologian. 1. Choosing. On October 28, 1945 the French philosopher Jean-Paul Sartre (1905-1980) gave a talk at the Club Maintenant in Paris to a surprisingly large crowd He concluded by telling the story of an ex-student who had come to him for advice during World War II. The young man's brother had been killed in battle in 1940 fighting the Germans. His father became a collaborator with the Germans and deserted the family. This young man was his mother's only support and companion.5 The young man really wanted to go across the border through Spain to England where he hoped to fight the Nazis with the Free French forces in exile. In this way he longed to avenge his brother, defy his father and save his country. The only problem was that there would be no one to care for his mother during this time of food shortages and violent upheaval. How do you decide between contributing to the greater good and caring for your mother? According to Sartre established authorities like priests and scholars have nothing to offer. Our inner voice is also confused by competing values. We wonder if we are deceiving ourselves. In short, nothing can relieve us of the burden of freedom. Social conventions, our history, psychology and habits are what he calls "the situation" in which we act. But they do not finally determine what we will do. We are free to choose and in that decision we become who we will be. With each decision we create our self. Although the young man faces a particularly dramatic decision, all of us are in the same situation. We are compelled to invent who we will be. In every instant we are determining what kind of a relationship we will have with God. We can be so busy with our careers and our cell phones that we create a self that is incapable of sitting still and listening to Jesus. 2. Loving. The turn of the twentieth century Harvard philosophy professor Josiah Royce (1855-1916) grew up in Grass Valley California. As a boy he would visit the grave of a gold prospector behind his house and wonder what it would feel like to live and die so anonymously, alone and far from home. He always felt a bit like an outsider.6 Royce's son Christopher was diagnosed with "acute abulia" a mental illness that we might call depression today and died in his twenties. While his colleagues emphasized experience and individualism Royce talked about community. Royce worried about the way modern life seems to detach and isolate us. He always emphasized the importance of belonging to a greater whole, of our loyalty to, even our love for, this world entrusted to our care. One of his students William Ernest Hocking (1873-1966) with his wife Agnes wrote a book called The Meaning of God in Human Experience. The tile of Chapter 23 is "Prayer and its Answer."7 They call prayer active, a way of seeking the Divine through worship. The answer comes when we passively and effortlessly receive God. They write, "The best known of all experiences of [this] mystic type is that of discovering the individuality of another person."8 Mary discovers Jesus in just this way. We too meet Jesus in our deepest connections with other people. 3. Joyfully. The theologian Karl Barth (1886-1968) writes that our humanity arises out of what he calls being in encounter, from the quality of our relationships with other people. This is always a reciprocal relationship. It involves really sharing ourselves and being genuinely open to someone's real differences from us. He describes four elements to this. First, it means really looking another person in the eye in a way that allows our self to be seen. Second, it involves really listening to others and speaking the truth about ourselves. Third, it means being ready to help and to be helped. But these are not enough. To really be human we need to do these things "gladly." At our very heart, if we do not do something gladly, it is not who we really are. Our fundamental humanity is not something that we can just choose to put on or take off like a hat.9 If someone said "be joyful!" you might wonder where to start and what to do. We usually regard joy as a passing feeling that just happens to us rather than a habitual disposition that shapes our experience of the world. If you really want to experience joy you need to realize that it comes to us when we cultivate a sense of gratitude and humility. Joy arises out of a life of prayer. Anne Lammott writes that the most essential prayers fall into three categories that can be each described with a single word. "Help. Thanks. Wow." In each of these moments turning to God leads us more deeply into an experience of gladness. In conclusion, like a good coach or better like a true friend, Jesus tells us the story that will transform our lives, so that some good may come of the suffering that is uniquely our own. As I listen at the feet of Christ this week I am learning that we can be free from the past, that with every choice we can draw closer to God and create something beautiful with who we are. Just as Jesus calls Martha in from her solitary work, he invites us also to step out of the isolating individualism of our culture and to seek that mystic experience of the holiness present in every person. The cares and anxieties that we take on do not have to own us. By living with gratitude, humility and love we can open find abiding joy. Let us pray: As Martha served you, Lord, so too may we with faithful hearts and loving care prepare all things for your feast. But grant us more, O Lord, that as we work we may be tuned with Mary’s ear to hear in all we do, the lessons that you teach. Amen (Adapted from Lucy Mason Nuesse).10 1 Chad Harbach, The Art of Fielding (NY: Back Bay Books, 2011) 149. 2 Jonathan Edwards, "The Excellency of Christ." http://www.leaderu.com/cyber/books/edwards/excellency.html 3 7 Pent (7-19-98) 11C. 4 On these two commandments hang all the law and the prophets. 5 Sarah Bakewell, The Existentialist Café: Freedom, Being, and Apricot Cocktails (NY: Other Press, 2016) 7-9. 6 John Kaag, American Philosophy: A Love Story (NY: Farrar, Straus and Giroux, 2016) 165ff. 7 William Ernest Hocking, The Meaning of God in Human Experience: A Philosophic Study of Religion (New Haven, Connecticut, Yale University Press, 1912). https://archive.org/stream/meaningofgodinhu027626mbp/meaningofgodinhu027626mbp_djvu.txt 8 Ibid., 175. 9 Karl Barth, Church Dogmatics III.2: The Doctrine of Creation tr. H Knight, G.W. Bromiley, J.K.S. Reid, R.H. Fuller (NY: T & T Clark, 1960) 267. 10 Diocesan Altar Guild (6-19-04) 11C.
11C الممتحنة تفسیر 9-8
11C المعارج لفظی ترجمہ 1-35، تفسیر 3-1
SMA student, Thalia from 11C, discusses her religious background and discrimination.
On January 30, 2018, Ernest V. Garcia and Robert A. deKemp discussed Robert’s article entitled ‘Repeatable and reproducible measurements of myocardial oxidative metabolism, blood flow and external efficiency using 11C-acetate PET’. The authors of this article have provided a PowerPoint file which summarises the contents of the paper and is free for re-use at meetings and presentations: http://bit.ly/2nCbaNy The article is available at: https://rdcu.be/Ml0W Be sure to subscribe on your mobile device - search 'JNC/ASNC Podcast'.
11C المعارج تفسیر 35-19
In this episode, we discuss style 11C, Strong Bitter. Beers tasted include: Bass Ale Full Sail ESB Red Hook ESB Fuller's ESB Plus, we eat some Chinook hop pellets!
Jamil, Tasty and Jon Plise discuss Northern BJCP category 11C, Northern English Brown Ale, in this episode of Brewing With Style.
This episode is dedicated to the lovely bundle of farts in 11C. #FartsOnAPlane
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.04.10.035352v1?rss=1 Authors: Norgaard, M., Beliveau, V., Ganz, M., Svarer, C., Pinborg, L. H., Keller, S. H., Jensen, P. S., Greve, D. N., Knudsen, G. M. Abstract: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the human brain and plays a key role in several brain functions and neuropsychiatric disorders such as anxiety, epilepsy, and depression. The binding of benzodiazepines to the benzodiazepine receptor sites (BZR) located on GABAA receptors (GABAARs) potentiates the inhibitory effect of GABA leading to the anxiolytic, anticonvulsant and sedative effects used for treatment of those disorders. However, the function of GABAARs and the expression of BZR protein is determined by the GABAAR subunit stoichiometry (19 genes coding for individual subunits), and it remains to be established how the pentamer composition varies between brain regions and individuals. Here, we present a quantitative high-resolution in vivo atlas of the human brain BZRs, generated on the basis of [11C]flumazenil Positron Emission Tomography (PET) data. Next, based on autoradiography data, we transform the PET-generated atlas from binding values into BZR protein density. Finally, we examine the brain regional association with mRNA expression for the 19 subunits in the GABAAR, including an estimation of the minimally required expression of mRNA levels for each subunit to translate into BZR protein. This represents the first publicly available quantitative high-resolution in vivo atlas of the spatial distribution of BZR densities in the healthy human brain. The atlas provides a unique neuroscientific tool as well as novel insights into the association between mRNA expression for individual subunits in the GABAAR and the BZR density at each location in the brain. Copy rights belong to original authors. Visit the link for more info