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Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Alprazolam is a short-acting benzodiazepine that enhances the inhibitory effects of gamma-aminobutyric acid (GABA) at the GABA-A receptor. Clinically, this results in anxiolytic, sedative, muscle-relaxant, and anticonvulsant effects. After oral administration, alprazolam is rapidly absorbed, with onset of action typically within 30–60 minutes. It undergoes extensive hepatic metabolism primarily via CYP3A4 to inactive metabolites, and has an elimination half-life of approximately 11 hours, which may be prolonged in elderly patients or those with hepatic impairment. Common adverse effects include sedation, dizziness, impaired coordination, and cognitive slowing. More serious risks include respiratory depression, especially when combined with opioids, alcohol, or other CNS depressants. Clinically, alprazolam should be used at the lowest effective dose for the shortest possible duration. Abrupt discontinuation should be avoided; gradual tapering is essential to reduce withdrawal risk. It is a controlled substance that carries the risk of addiction and dependence. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources! NAPLEX Study Materials BCPS Study Materials BCACP Study Materials BCGP Study Materials BCMTMS Study Materials Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101
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Most of us don't realize how much alcohol affects our bodies until we take a break. In this first episode of Office Hours, I break down what really happens when you give up alcohol for 30 days. Alcohol impacts nearly every system—from your brain and hormones to your gut, liver, and immune system—but the good news is your body begins repairing itself far faster than most people expect. I discuss: • What alcohol really is—and why the “buzz” is actually your brain slowing down• How alcohol affects neurotransmitters like GABA, dopamine, and glutamate• Why even moderate drinking disrupts sleep, mood, hormones, and metabolism• How alcohol impacts the liver, gut microbiome, immune system, and cancer risk• Why hangovers feel like the flu—and what's actually happening in your body• What happens when you stop drinking, week by week, from detox to deep repair• The surprising benefits to energy, focus, skin, sleep, and emotional resilience• Practical tools to manage cravings, social pressure, and sleep disruption• Why community support makes behavior change easier and more sustainable Your body has an incredible ability to heal and often, it just needs you to take your foot off the gas. Try it for 30 days. You may be amazed by how different you feel. If you want extra support, join us for the Hive January Challenge, where we'll guide you through the process, track progress, and share experiences together. Visit functionhealth.com for 160+ lab tests at just $365 a year. Helpful Resources: Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive Have a question you'd love answered on the podcast? Submit it here
Struggling with weight loss and stubborn belly fat despite a healthy diet and exercise? Discover the best bedtime drink for weight loss to help break a weight loss plateau and lose belly fat faster.
In this conversation, Cheryl McColgan discusses the significance of establishing a wind down routine before bed to enhance sleep quality. She emphasizes the importance of calming activities, such as reading, warm baths, and reducing screen time, to prepare the body and mind for sleep. Cheryl also touches on the use of sleep supplements and tools to improve sleep, highlighting the critical role of good sleep in overall health and wellness. Takeaways Create a simple wind down cue before bed.Calm your brain and nervous system for better sleep.Screen time at night is a poor habit for sleep.Reading before bed can help you relax.Warm baths signal your body to calm down.Turning off bright lights aids in winding down.Sleep is critical for health and longevity.Good sleep supports weight loss and fat loss.Consider a warm drink as part of your bedtime routine.Engage with others about effective wind down routines. Disclaimer: Links may contain affiliate links, which means we may get paid a commission at no additional cost to you if you purchase through this page. Read our full disclosure here. CONNECT WITH CHERYL Shop all my healthy lifestyle favorites, lots of discounts! 21 Day Fat Loss Kickstart: Make Keto Easy, Take Diet Breaks and Still Lose Weight Dry Farm Wines, extra bottle for a penny Drinking Ketones Wild Pastures, Clean Meat to Your Doorstep 20% off for life Clean Beauty 20% off first order DIY Lashes 10% off NIRA at Home Laser for Wrinkles 10% off or current promo with code HealNourishGrow Instagram for daily stories with recipes, what I eat in a day and what’s going on in life Facebook YouTube Pinterest TikTok Amazon Store The Shoe Fairy Competition Gear Getting Started with Keto Resources The Complete Beginners Guide to Keto Getting Started with Keto Podcast Episode Getting Started with Keto Resource Guide Episode Transcript Cheryl McColgan (00:00.078)Hey everyone, I’m Cheryl McColgan, founder of HealNurshGrow and welcome to day four of your healthy habits challenge. Today’s habit is very simple, but it’s so powerful and it has to do with one of the things that I think is one of the most underappreciated aspects of health and that is sleep. And so the habit that we’re going to do today is to create a simple wind down cue before bed. So what this does is basically gets you ready for sleep, starts to calm your brain, starts to calm your nervous system so that you can actually get in bed and go to sleep instead of getting in bed and staying wired for multiple minutes or even hours after that. Definitely something we want to avoid. So having this consistent wind down cue is exactly what it does. Cues your brain and your body to be ready for sleep and to start to calm down. There’s any number of things that this could possibly be for you. One of the things that you will have heard from many people in the past, and this is so true, is that screen time at night is really a poor habit to have to get good sleep. So maybe your wind down cue is putting your phone in the other room and putting it on the charger before you get ready for bed. That’s a great way to do that. It also cuts down on the blue light. So that will allow your body to produce melatonin, which gives you better sleep. But this cue is something you want to do consistently every day, just so that it gives again, your brain and your body that idea that it’s time to calm down. Another thing that people really like doing for this type of cue is to simply do some reading before bed. And so again, not reading on a device like your computer or your phone, but maybe an old school book. I know that sounds crazy or the the Kindles now have, they don’t have any blue light coming off of them. And just reading is just very calming in the evening. It’ll put you right to sleep. Even books that you’re in love with and excited about. Sometimes it’s like, it just starts to get you very drowsy and you want to ideally do it in bed. as soon as you really start to get sleepy, you just put the book aside and go to sleep. Cheryl McColgan (02:16.782)Another one that’s great for bedtime is a warm bath. The whole reason that this works is warming up your body. And ideally you want to do it maybe an hour to an hour and a half before bed. But again, it’s a relaxing activity. It’s something that signals it’s time to calm down and get ready for sleep. But it also has a physiological response in the body where you warm up your body temperature a little bit. Then when you get out and it starts to come back down, your body temperature coming back down actually makes you sleepy. So that’s another good one. But really any of these, can be anything that works for you. You just want it to be something that you can do on a consistent basis and that actually helps calm your nervous system. So it could also be, you know, a breathing exercise or some light stretching or, you know, anything like that, that’s going to make going to bed easier for your body. Another one is, Turning off bright lights. So maybe your cue for your wind down is to go around your house and turn off all the lights and maybe you just have like a gentle Red light in the room or just dim lights in your room as you’re winding down But just doing those cues time after time eventually it gets your body to a place where It’s calm enough and it’s ready some other things that I use for sleep since we’re talking about sleep sometimes just a wind down cue is not enough for some people but Again, I think if you practice it on a consistent basis, that’s going to change over time where it really does help you get to sleep. But there’s other things. There’s supplements you can take. mentioned melatonin. I actually wouldn’t recommend taking that on a regular basis because it does tend to make you feel groggy in the morning. In addition to that, it can also affect your own melatonin production over time. So that’s kind of not as recommended. But there’s plenty of sleep supplements. Sorry, I was losing my word there. Sleep supplements out there. that I’ve tried, I’ve used a brand called Dream. I had a new one sent to me that was from, the company’s escaping me. It’s kind of a funny name, but I’ll link it in the show notes. So also that could be part of your ritual is if it’s both of these drinks are kind of like a hot cocoa that you drink at night that has magnesium, GABA, some other sleep inducing things in it. So that could be your ritual is to make your nice warm drink, go get in your bed, sit that, relax, and then. Cheryl McColgan (04:38.434)go to sleep. So that’s one of the tools that I tend to use a lot. And then I’ve also talked a lot about in the past that I use a bed cooling pad. So I’m menopausal age, unfortunately. And a few years ago, I started getting horrible night sweats where it just really interrupted my sleep. So I started using a cooling pad on my bed about five years ago. And now it is so hard for me to sleep without it because it actually not only cools you but warms you as well. and can use it to like gently warm the bed as your, almost as your alarm clock. Instead of using a harsh alarm, it just starts to warm up your body and wake you up very naturally. So depending on where you are with sleep, this wind down cue is a great start. And that’s all we’re looking for in this challenge, right? Just trying some new little habit snacks that you can see if it works for you or you can see if it would do you good to add it on in the future. But this is just the beginning. So sleep is such, like I said, such a critical and underappreciated thing for health, longevity, for weight loss even, helps with fat loss. I mean, there’s so many reasons why you want to get good sleep, but this is just a small way that you can get started. Start repeating this if it speaks to you. If you’re someone that has trouble with sleep, I highly recommend that you take this one on and keep it for the rest of the challenge and beyond, because it will only help you. It may not be enough, like I said, but it is great stars. So some of those things that I mentioned, I’ll make sure I link them in the show notes. But for now, just create your simple wind down cue before bed. Try it out, see how you sleep and let me know in the comments if this works for you. If you already have a wind down routine, I’d love to hear about it because I think everybody wants to hear some good ideas if they can’t think of anything that works for them or speaks to them. So definitely let me know if you have any tips and we can share them with everybody else in the comments. OK. See you again tomorrow.
What happens when your family stages an intervention because they've been avoiding you 10 days every month?I'm sharing the story of a patient who had a complete breakdown at Christmas dinner. She snapped at her husband, her kids, her mom, her in-laws—everyone. A few hours later, her family told her: "We love you, but for 10 days every month, we actively avoid you."She came to me asking: Am I bipolar? Am I manic? What's happening to me?This is PMDD premenstrual dysphoric disorder. And when it collides with perimenopause, it becomes a perfect storm. This is not just PMS. This isn't you being dramatic. It's a real biochemical thing happening in your brain an abnormal response to normal hormonal changes.I discuss the science of PMDD: how GABA receptors respond to progesterone metabolites, why some brains are change sensitive, and why the hormonal volatility of perimenopause (erratic estrogen, declining progesterone, unpredictable timing) makes everything exponentially worse. I explain treatment options from luteal-phase SSRIs to Yaz to Duavee for refractory cases, and why tracking your symptoms for at least two cycles is critical for diagnosis.Highlights:Why "I feel like I'm watching myself burn down my life and can't stop it" is the hallmark of PMDD.The DRSP tracking tool: why you need 2 cycles to diagnose PMDD properly.Why Vitex (chasteberry) might help mood swings and breast pain.What Duavee is and why it works for women who can't tolerate progestins.Why Dr. Tammy Rowan calls PMDD a progesterone sensitivity issue.Ulipristal: the emergency contraception drug being studied for PMDD.If you've ever felt like your brain gets hijacked on a schedule, if you've felt completely out of control, this episode is for you. Track your symptoms. Find a clinician who takes cyclic mood symptoms seriously. You don't have to live like this. Please share this episode with someone you know might be experiencing this or a clinician you think would benefit from it.Resource:DRSPDr. Tami RowenGet in Touch with Me:WebsiteInstagramYoutubeSubstackMentioned in this episode:GSM CollectiveThe GSM Collective - Chicago Boutique concierge gynecology practice Led by Dr. Sameena Rahman, specialist in sexual medicine & menopause Unrushed appointments in a beautiful, private setting Personalized care for women's health, hormones, and pelvic floor issues Multiple membership options available Ready for personalized women's healthcare? Visit our Chicago office today. GSM Collective
In this episode of Accelerated Health with Sara Banta, I'm joined by Dr. Scott Sherr, a Health Optimization Medicine and Hyperbaric Oxygen Therapy Physician, to uncover the incredible role GABA plays in supporting your brain, body, and overall wellness.We discuss how GABA impacts stress, sleep, mood, and energy, and why this powerful neurotransmitter could be the key to unlocking better mental clarity and physical performance. Dr. Sherr also shares cutting-edge insights from health optimization medicine and practical tips you can implement today.Whether you're struggling with sleep, stress, or low energy, this episode is packed with science-backed strategies and actionable advice to help your body and brain thrive.
You're not weak, broken, or lacking discipline. If you keep reaching for food at the end of a long day, there's nothing wrong with you—there's something going on inside you. In this episode, we break down what's really happening in your brain and body when emotional eating shows up (especially in the evening), and why willpower alone isn't the answer.This isn't about blaming your cravings on “bad habits”—it's about understanding the biology behind them so you can finally stop fighting yourself and start supporting your nervous system instead.We'll cover what's actually happening with your dopamine and GABA levels, why your brain shifts into survival mode, and simple tools to regulate your body and create better routines that don't rely on food to soothe. No shame, no restriction—just science, compassion, and strategies that work in real life.What you'll learn:Why your brain turns to carbs, sugar, or wine in moments of overwhelmWhat's really driving emotional eating (hint: it's not hunger)The “brain battery” metaphor that explains your low-willpower momentsHow to use simple pattern interrupts, sensory shifts, and micro-boundariesWhy predictability = safety, and how to use that to rewire your habitsTools that take 30–90 seconds—but create powerful changeYou don't need more willpower. You need better tools—and the right kind of support.Support the showGet Weekly Health Tips: thrivehealthcoachllc.com Join the Thrive Collective Facebook group Let's Connect:@ashleythrivehealthcoach or via email: ashley@thrivehealthcoachingllc.com Podcast Produced by Virtually You!
Butyrate, produced by gut bacteria when they ferment dietary fiber, acts as a signaling molecule in the gut-brain axis, influencing stress, pain tolerance, immunity, and brain health Through multiple mechanisms, including specific enzyme inhibition and NF-κB pathway regulation, butyrate reduces neuroinflammation and protects against neurodegenerative conditions like Alzheimer's and Parkinson's disease Butyrate influences key neurotransmitters including GABA, serotonin, and dopamine, while also increasing brain-derived neurotrophic factor (BDNF), which supports neuronal growth and cognitive function The vagus nerve serves as a communication highway between the gut and the brain, transmitting signals about butyrate levels that affect mood regulation, stress response, and immune function Optimizing gut health through dietary fiber and homemade fermented foods helps promote butyrate production and maintain a healthy gut-brain connection
Vintage drug ads promised calm mornings, slimmer silhouettes, and instant relief from restless nights. We dig beneath the glossy slogans to unpack how Black Beauties, Quaaludes, Miltown, Barbiturates, and Purple Hearts shaped the path to today's mediations—and what that history teaches us about safety, dependence, and withdrawal. With clear explanations of GABA, tolerance, and cross‑tapering, we connect old “uppers and downers” to modern clinical practice and the real risks people still face.I share why amphetamines jumped from diet pills to productivity boosters, how tranquilizers won hearts and airwaves, and why barbiturates' direct receptor action made them both effective and uniquely lethal. We explore the strange logic of combining a stimulant with a sedative in a single pill, the concept of the therapeutic index that flipped prescribing habits, and the cultural pressure—often aimed at women—that fueled demand for daily sedation. You'll hear how benzos improved the safety margin, where they still go wrong, and how clinicians now use careful tapers, screen for polysubstance use, and apply harm‑reduction strategies to prevent overdose.If you've ever wondered why some drugs vanished and others became standard, this deep dive brings context, clarity, and practical takeaways. You'll walk away able to explain the difference between narrow and wide therapeutic indexes, why withdrawal from certain depressants is so dangerous, and how our field balances relief with risk. Subscribe, share with a colleague who treats anxiety or addiction, and leave a review with the one historical ad or insight that surprised you most.To contact Dr. Grover: ammadeasy@fastmail.com
Resolve to change without making your body the battleground. In this week's episode I unpack why self-sabotage spikes for women in their 40s and 50s and explain, with clarity and compassion, how a survival-focused brain chooses short-term comfort over long-term goals when hormones, stress, and diet history collide. Rather than blaming willpower, I reframe self-sabotage as protection, then map a kinder, more effective path forward.I get practical about the peri and postmenopause landscape: declining oestrogen and progesterone affecting serotonin, dopamine and GABA, cortisol spikes during the festive season, and the dieting fatigue that primes the mind to expect failure. I walk through the emotional eating loop—stress, soothe, shame, restrict, repeat—and shows why removing foods without adding regulation guarantees a rebound. You'll learn why willpower is lowest when you need it most and how to build results on safety, structure, nourishment, compassion and accountability.Across six actionable steps, I share how to neutralise food language, stabilise blood sugar with protein-forward, regular meals, and use simple nervous system tools like slow breathing, grounding and reducing overstimulation. I show how shrinking goals creates momentum, how curiosity replaces shame, and why supportive accountability turns consistency into a habit. If you're tired of starting over each January, this conversation offers a steady plan to feel calm, supported and finally in control.If the episode resonates, follow, share with a friend who needs to feel seen, and leave a quick review to help more women find the show.Send me a text!Are you a woman feeling stressed, flat and experiencing the challenges of perimenopause or menopause? It's time to reclaim your youthful energy, radiance and self-assurance (and your ideal weight). I'm here to help with my proven method. Here's how I can support you - 1. Hit your health and wellbeing goals this year, balance your hormones and lose weight with your own personalised protocol, based on your body's biochemistry. Sounds awesome right!! Book a free 30 minute Peri Weight Loss Assessment with me so we can discuss your health and wellbeing goals and also see how I might be able to support you. Book your call here. 2. Follow me on Instagram and Facebook - @the.perimenopause.path 3. Join the waitlist for my innovative NEW 8 week group program, In Your Skin™️, for women in perimenopause and post-menopause who want effective solutions to manage skin changes at this time of life.
In this episode, we're revisiting some of the most magical moments and scientific milestones of 2025 - including the incredible legacy of Dame Jane Goodall, the brain-wave reading bionic-knee, why labradors are so greedy, and the beer that doesn't give you a hangover... Like this podcast? Please help us by supporting the Naked Scientists
A couple weeks before Christmas, Carrie shares a real-life update on her alcohol-free journey ~ what's changed, what's surprised her, and why this has become one of the most powerful shifts for her energy, mood, clarity, and presence.She's joined by her friend and mentor Maureen Benkovich, certified Alcohol Freedom & Wellness Coach and host of the Sober Fit Life podcast, for an honest conversation about the why behind “gray area drinking,” the science of what alcohol does to brain chemistry (dopamine, serotonin, GABA), cortisol, sleep, and gut health ~ and why the impact can linger far longer than most people realize.Together, they unpack Maureen's updated 4R Method (Recognize, Replace, Rewire, Renew), how to navigate “alcohol-free firsts” (holidays, weddings, travel, dinners out), and why freedom doesn't require rock bottom ~ just a willingness to get curious and give your body a true break.If you've ever wondered whether alcohol is quietly keeping you stuck in fatigue, anxiety, brain fog, inflammation, or irritability, this episode is your gentle nudge and your science-backed roadmap.Visit soberfitchick.com for details on Maureen's upcoming Six-Week Alcohol Reset (beginning January 12, 2026) and her podcast Sober Fit Life. Connect with MaureenWebsite: https://www.soberfitchick.com/Facebook: https://www.facebook.com/maureen.benkovich/Instagram: @soberfitchickllcAbout MaureenMaureen Benkovich is the founder of SoberFit Chick Coaching and a certified gray area drinking coach. With a warm, science-backed approach, Maureen empowers individuals to break free from the grip of alcohol and reconnect with their full potential. Drawing on her personal journey and professional expertise, she combines empathy, neuroscience, and practical strategies to help clients make sustainable changes and thrive in every aspect of their lives.Maureen's unique coaching philosophy blends her deep understanding of health, fitness, and the brain's chemistry to guide clients toward healthier habits and a more fulfilling lifestyle. Her mission is to help others uncover the truth about alcohol and build a life that aligns with their goals and values.Follow Carrie on:Instagram: https://www.instagram.com/carriechojnowski/Facebook: https://www.facebook.com/carrie.o.chojnowskiVisit https://thrivewithcarrie.com/ to book a free discovery call!See you next time!Disclaimer: The information provided in this podcast is for entertainment and educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment.
番組概要: ■メゾン マルジェラが初の住宅プロジェクト、「メゾン マルジェラレジデンス」を発表■「ドリス ヴァン ノッテン」が京都に日本初のギャラリーをオープン パリやミラノなどに続く4店舗目■ギャップ、美容分野への進出を拡大 傘下の「オールドネイビー」で新ライン発売■ラングラーが「幻のジーンズ」と呼ばれる1964年モデルを初復刻■大丸松坂屋のファッションサブスク「アナザーアドレス」がリアル進出 来年2月から約4ヶ月限定オープン■サッポロビールとミズノが「スポーツノンアルビール」を開発 運動後に飲みたい味を追求【今週のワイン】ラウ・ヴァイス<ドイツ・オレンジ>【オフトピ】ニトリの「横向き寝が楽なまくら」327万個を突破 “いまなお”売れ続ける理由【買ったものリスト】ざま:GABA ギャバ&テアニン 60粒、マグネシウムグリシネートヨッシー:象印マホービン 加湿器 スチーム式 4.0L グレー、ブルーエア 空気清浄機 22畳【出演者】ヨッシー、ざま、ちはらファッションに関する質問やお悩み相談など、皆様からのメールをお待ちしています!番組に対するメールはpodcast@fashionsnap.comまで。【こちらのフォーム】からもお送りいただけます。
You've just been promoted to a manager. Now what? The truth is that new managers hardly receive formal training before taking on their roles. Instead of hitting the ground running, most of them try to figure out how to lead as they go along, says Vibha Gaba, The Berghmans Lhoist Chaired Professor of Entrepreneurial Leadership and Professor of Entrepreneurship at INSEAD.In this podcast, Gaba takes a deep dive into leading, especially for first-time managers. Being a leader in the contemporary workplace clearly requires new competencies; technical expertise alone is no longer enough. As the director of INSEAD's “Learning to Lead” executive programme, Gaba has been training executives, complementing their existing technical chops with people management skills – from how to assign tasks to the right team members to coaching people and managing conflicts.
Anne Ghesquière reçoit le nutritionniste Olivier Bourquin. Cortisol, sérotonine, dopamine, GABA. Quel rôle jouent nos hormones et neurotransmetteurs dans notre énergie, notre motivation, notre appétit ou notre sérénité ? Mais que se passe-t-il vraiment dans notre corps lorsque nous sommes fatigués, irritables, stressés ou que notre sommeil se dérègle ? Le système nerveux autonome est-il la clé de notre santé globale ? Comment agir concrètement sur notre alimentation, notre respiration, notre sommeil ou notre activité physique pour retrouver l'équilibre ? Olivier Bourquin propose une approche holistique et accessible pour comprendre ces messagers du corps et reprendre la main sur notre vitalité. Son livre Cortisol, dopamine, sérotonine… La révolution des hormones et des neurotransmetteurs, est publié aux éditions Eyrolles. Épisode #649Quelques citations du podcast avec Olivier Bourquin :"Ouvre tes narines et ferme ta bouche et tout tout ira mieux.""La fonction générale d'un être humain, ce serait d'être serein.""Si je mange bio et que je ne mâche pas, ça n'a aucun intérêt de manger bio."Recevez chaque semaine l'inspirante newsletter Métamorphose par Anne GhesquièreDécouvrez Objectif Métamorphose, notre programme en 12 étapes pour partir à la rencontre de soi-même.Suivez nos RS : Insta, Facebook & TikTokAbonnez-vous sur Apple Podcast / Spotify / Deezer / CastBox / YoutubeSoutenez Métamorphose en rejoignant la Tribu MétamorphoseThèmes abordés lors du podcast avec Olivier Bourquin :00:00Introduction02:00Présentation invité04:23L'injonction à la performance06:38Une approche holistique de la santé09:22Détecter le manque de N.O11:42Le rôle de la dopamine13:05Préférences motrices et différents profils16:34Bien réguler sa dopamine19:34Sérénité et sérotonine21:54Le rôle fondamental de l'acétylcholine25:21Le GABA, tour de contrôle du cerveau28:09L'impact d'un cortisol déséquilibré29:43Les enjeux hormonaux chez la femme31:57Comment réguler le cortisol33:01Stimuler son nerf vague41:13Bouche ouverte et mouth taping43:33Profils MBTI et profils hormonaux ?46:00Le profil Rationnel ou dopaminergique46:20Le profil Idéaliste ou cholinergique48:10 Le profil Artisan ou sérotoninergique48:53Le profil Gardien ou GABAergique51:18Test pour connaître son profil53:24Conseils nutrition57:59L'enjeu de l'eau01:01:27Un jeûne intermittent adapté01:03:00La routine d'Olivier Bourquin post burn-outAvant-propos et précautions à l'écoute du podcast Photo DR Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Discover the seven critical alcohol effects on body systems, from blood sugar disruption and gut inflammation to hormone imbalances and liver stress. Whether you're an occasional drinker or weekend regular, understanding how alcohol impacts your health—from brain function to cancer risk—helps you make informed choices and recover smarter. FEATURED PRODUCT NAC+ – featuring N-Acetyl Cysteine and selenium, is specifically designed to support your liver's ability to produce powerful antioxidants that combat oxidative stress from alcohol consumption. As discussed in this episode, alcohol depletes critical nutrients like selenium while generating excessive cellular damage. NAC+ helps your liver reduce oxidative stress, supports detoxification pathways, and replenishes the exact minerals that alcohol depletes—making it essential for anyone who drinks, whether occasionally or regularly. get it here: https://mswnutrition.com/products/nac 5 KEY TAKEAWAYS Blood Sugar Disruption – Alcohol converts directly into blood sugar and is stored as fat in the liver, contributing to pre-diabetes and fatty liver disease that affects one in four people worldwide. Gut & Liver Inflammation – Alcohol acts as a toxin that damages gut lining, disrupts the microbiome, causes leaky gut, and generates oxidative stress that your liver must work overtime to neutralize. Neurotransmitter Imbalance – While alcohol temporarily boosts serotonin, dopamine, and GABA, it severely disrupts sleep quality, increases anxiety and depression risk, and prevents proper brain detoxification during rest. Mineral Depletion – Alcohol's diuretic effect causes critical loss of selenium, zinc, magnesium, and potassium—minerals essential for liver function, antioxidant production, and cellular protection. Hormone & Cancer Risk – Long-term alcohol consumption suppresses testosterone, increases estrogen through aromatization, and is classified as a carcinogen linked to multiple cancer types including liver, breast, and colorectal cancers. TIMESTAMPS 00:00 – START 02:00 – Why alcohol is classified as a severe toxin 05:00 – Effect #1: Blood sugar disruption and fatty liver development 09:00 – Effect #2: Inflammation, leaky gut, and microbiome destruction 13:00 – Effect #3: Liver stress and oxidative damage 17:00 – Effect #4: Neurotransmitter imbalance and sleep disruption 22:00 – Effect #5: Electrolyte and mineral depletion (selenium & zinc) 26:00 – Effect #6: Hormone disruption and testosterone suppression 29:00 – Effect #7: Cancer risk and carcinogenic properties 32:00 – Mediterranean diet, resveratrol, and supplement alternatives 35:00 – Final recommendations for liver support and recovery RESOURCES Diabetes and Alcohol – https://www.mountsinai.org/health-library/selfcare-instructions/diabetes-and-alcohol Does Alcohol Cause Inflammation – https://www.verywellhealth.com/does-alcohol-cause-inflammation-8403645 Alcohol Consumption and Antioxidant Defense – https://pmc.ncbi.nlm.nih.gov/articles/PMC7357092/ Alcohol and Brain Neuroadaptive Changes – https://pmc.ncbi.nlm.nih.gov/articles/PMC11718584/ Sex and Stress Hormones in Alcohol Consumption – https://pmc.ncbi.nlm.nih.gov/articles/PMC7374925/ Alcohol and Aromatization – https://ai.hubermanlab.com/s/6PV5jyTa How Does Alcohol Affect the Microbiome – https://www.mdanderson.org/cancerwise/how-does-alcohol-affect-the-microbiome.h00-159696756.html CONNECT
Send us a textHow ketosis and ketogenic diets work and how these tools can improve metabolic health, brain function, and even cancer management.Topics Discussed:Organs have different fuel preferences: brain strongly prefers glucose, heart prefers fatty acids, skeletal muscle is flexible and likes fat/ketones.Humans evolved with high metabolic flexibility; regular ketosis was normal for ancestors, but today most people never experience it.“Keto flu” is largely glucose withdrawal plus electrolyte/sodium loss; proper salt and hydration prevent most symptoms.Classic medical ketogenic diet is ~90% fat (historically saturated); modern versions often use more monounsaturated fats, MCTs, and higher protein.Saturated fat is not inherently atherogenic in the context of weight stability or caloric deficit; excess calories from any source can dysregulate metabolism.Exogenous ketones (e.g. BHB) provide energy, reduce ROS, stabilize membranes, increase inhibitory tone (GABA), and have hormone-like signaling effects independent of diet.Cancer cells often show Warburg effect (damaged mitochondrial respiration → heavy reliance on glycolysis); lowering glucose and raising ketones can stress cancer cells.True keto-adaptation for athletic performance requires 6–12 weeks; after that, elite athletes can match or exceed prior high-carb performance at sub-maximal and endurance efforts.Practical Takeaways:Therapeutic carbohydrate restriction (50–100 g/day for many people) plus occasional fasting or ketone supplements can restore metabolic flexibility with far fewer side effects than strict keto.Prioritize whole-food fats (eggs, fatty fish, beef, olive oil, butter/lard) and minimize processed keto products loaded with seed oils.Supplementing BHB (salts or esters) or MCT oil can ease the transition into ketosis, boost ketones without strict dieting, and may support brain and metabolic health.Regularly check basic blood markers (glucose, lipids, electrolytes) and consider an OmegaQuant test; optimizing metabolic health is one of the strongest preventable steps against cancer, neurodegeneration, and heart disease.Supplemental Ketone (BHB):KetoCitra—Ketone body BHB with potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off.*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts
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Where are you listening from?Your kitchen might be the best dispensary you'll ever have, but the real magic happens in your brain. We pull back the curtain on the endocannabinoid system and show how edibles—especially THC—bind to CB1 receptors, ripple through dopamine, GABA, and serotonin, and shape everything from euphoria to anxiety to time distortion. If you've noticed that your favorite gummy doesn't hit like it used to, there's a reason: tolerance builds as your brain downregulates receptors. The good news is that sensitivity can return faster than you think with a short, intentional break.Ready to reset your relationship with cannabis? We're launching the Fresh Start Tolerance Break Challenge for January—daily check-ins, weekly videos, science-backed tips, and a supportive community to help you rebuild sensitivity, save money, and return with intention. Whether you're new to edibles or a seasoned home cook crafting your own infusions, this guide gives you the science and structure to make every dose count.Join the Challenge, share this episode with a curious friend, and leave a review to help others find the show.Join the waitlist at JoinBiteMe.com/challenge - Music by Alexander BluSupport the show Visit the website for full show notes, free dosing calculator, recipes and more.
Dr. Scott Sherr is a Board-Certified Internal Medicine Physician Certified to Practice Health Optimization Medicine (HOMe), a specialist in Hyperbaric Oxygen Therapy (HBOT), and COO of Troscriptions (a Smarter Not Harder company). His clinical telepractice includes HOMe as its foundation alongside an integrative approach to HBOT that includes cutting-edge and dynamic HBOT protocols, comprehensive testing (using the HOMe framework), targeted supplementation, personal practices, synergistic technologies (new, ancient, psychedelic), and more. In this episode, Dr Sherr is discussing the science, therapeutic uses, and practical protocols for methylene blue and GABA-modulating compounds, and their roles in optimizing brain function, energy, sleep, and overall health. RESOURCES: Learn more about Dr. Sherr here: troscriptions.com, drscottsherr.com, onebasehealth.com Instagram: @troscriptions @drscottsherr @onebasehealth Get 15% off Peluva minimalist shoe with coupon code COACHTARA here: http://peluva.com/coachtara CHAPTERS: 0:00 Intro 3:35 What is methylene blue 8:45 MB dosage 17:00 How to start dosing 22:10 Methylene Blue IV 26:00 MB contraindications 29:00 Counterfeit & contaminated MB 36:00 Troscriptions products 39:00 GABA support 42:50 The effect of stress on mitochondria 48:45 Cannabis effects 52:20 Troscriptions stacks WORK WITH ME: Are You Looking for Help on Your Wellness Journey? Here's how I can help you: TRY COACH TARA APP FOR FREE: http://taragarrison.com/app LEVEL UP PROGRAM: http://taragarrison.com/level-up INDIVIDUAL ONLINE COACHING: https://www.taragarrison.com/work-with-me CHECK OUT HIGHER RETREATS: https://www.taragarrison.com/retreats SOCIAL MEDIA: Instagram @coachtaragarrison TikTok @coachtaragarrison Facebook @coachtaragarrison Pinterest @coachtaragarrison INSIDE OUT HEALTH PODCAST SPECIAL OFFERS: ☑️ Upgraded Formulas Hair Test Kit Special Offer: https://bit.ly/3YdMn4Z ☑️ Upgraded Formulas - Get 15% OFF Everything with Coupon Code INSIDEOUT15: https://upgradedformulas.com/INSIDEOUT15 ☑️ Rep Provisions: Vote for the future of food with your dollar! And enjoy a 15% discount while you're at it with Coupon Code COACHTARA: https://bit.ly/3dD4ZSv If you loved this episode, please leave a review! Here's how to do it on Apple Podcasts: Go to Inside Out Health Podcast page: https://podcasts.apple.com/us/podcast/inside-out-health-with-coach-tara-garrison/id1468368093 Scroll down to the 'Ratings & Reviews' section. Tap 'Write a Review' (you may be prompted to log in with your Apple ID). Thank you!
Chronically Low Neurotransmitters? Here's How They Destroy Brain Function | Podcast #467 Schedule a FREE Consult: https://www.justinhealth.com/consult Dr. J's New Thyroid Book: https://www.thyroidreboot.com Chronically low neurotransmitters can wreck your mood, focus, memory, and overall brain function — but the real question is why they get low in the first place. In functional medicine, we look deeper than "chemical imbalance." Mold toxicity, poor digestion, low adrenal output, and hormonal imbalances all play major roles in how your brain produces serotonin, dopamine, GABA, and more. In this episode, Dr. J breaks down the hidden drivers behind low neurotransmitters and how to restore healthy brain chemistry naturally. What You'll Learn: • Why low neurotransmitters cause anxiety, depression, and brain fog • How mold exposure blocks dopamine, serotonin, and GABA pathways • The role of gut function in neurotransmitter production and absorption • How low cortisol and adrenal fatigue disrupt brain chemistry • How low thyroid, estrogen, and progesterone affect mood and focus • The best strategies to rebuild neurotransmitters safely and naturally #LowNeurotransmitters #BrainFog #AdrenalFatigue #HormoneImbalance #MoldToxicity #FunctionalMedicine #GutBrainConnection #DrJustinMarchegiani Related Health Resources: Gluten Video Series: http://www.justinhealth.com/gluten-video-series Thyroid Hormone Balance Video Series: http://www.justinhealth.com/thyroid-hormone-balance Female Hormone Balance Video Series: http://www.justinhealth.com/female-hormone-balance Subscribe for More Videos: http://www.justinhealth.com/subscribe Dr. Justin Marchegiani's Links: All Resources & Socials: http://www.justinhealth.com/links References: Disclaimer: Some of the products featured in our content may earn us affiliate commissions. We only endorse products that we personally use and trust.
Send us a textIn this episode, we dive into one of the most underestimated foundations of autoimmune healing and hair recovery: sleep.So many people insist they “function fine” on six hours, a midnight bedtime, or restless nights — but the body tells a very different story. When you finally experience restorative sleep, the kind that calms inflammation, regulates the immune system, stabilises cortisol, and gives hair follicles the safety signals they need to grow, everything begins to shift. Less shedding. Clearer skin. A calmer gut. A more resilient mood and nervous system. More stable energy.Sleep is not passive; it is a biologically active repair state. And it's during deep sleep and early-night slow-wave sleep that the body performs its most profound healing: detoxifying the brain via the glymphatic system, recalibrating immune cells, lowering inflammatory cytokines, and supporting the hair cycle's transition back into growth.In this Friday 5, I break down the five science-backed levers that make the biggest impact on sleep quality for those with autoimmune conditions or alopecia — from nervous-system nutrients like magnesium, L-theanine and phosphatidylserine, to vagal tone practices, to circadian alignment, blue-light protection, and the often-resisted but deeply transformative 10pm repair window, when most cellular, hormonal and follicular repair occurs.This episode is for you if you've been feeling wired-but-tired, waking at 3am, noticing seasonal shedding, or living in a constant state of “pushing through.”By the end, you'll understand not just what improves sleep, but why these strategies work — and how they support full-body repair on a physiological level.BodyBio Calm – magnesium and taurine formula to lower stress and support GABA balance
The Sympathetic Spiral of Doom drains your mitochondria. Here's how to rebuild energy from within.
It is a staggering statistic that an estimated 90% of women and up to 50% of men in North America struggle with binge and emotional eating. For those caught in this exhausting cycle—marked by shame, frustration, and the feeling of being completely out of control—the common response is often another diet, followed by self-blame for lacking willpower. However, according to emotional eating and hormone expert Amber Romaniuk, focusing on willpower is exactly the wrong approach. Individuals are attempting to fix a deep, multi-layered issue with a surface-level solution. The true healing, she explains, requires digging deeper to uncover the root causes. The Real Root Causes Amber Romaniuk, drawing on her own challenging journey of gaining and losing over a thousand pounds, identifies two critical areas often overlooked: deep-seated emotional roots and the powerful influence of hormones. For many, the pattern of using food as a coping mechanism begins very early, often stemming from personal trauma or a pervasive feeling of not being safe or heard. Amber shares her own "origin story" of being bullied and called "fat and ugly" on the bus when she was five years old. This type of wounding, combined with growing up in a home with unprocessed grief and stress, can place the body into chronic survival mode, where food becomes a source of comfort. She explains, "I was in survival mode from a very young age." The Industry Trap This personal vulnerability is then exploited by a culture that profits from insecurity. Amber notes the irony that the diet, weight loss, food, and Hollywood media industries are the ones that created the problem by conditioning women and men to feel insecure and believe they must be "as skinny as possible." These same industries then sell the "solution"—diets, restriction, and over-exercise. This creates a trap: either complete loss of control with food or trying to grip control through restriction. The restriction inevitably leads to a binge, reinforcing the false belief that the individual is the failure, not the system. Amber is clear that this struggle has nothing to do with willpower; these are the "lies that were sold by the industry." How Hormones Fuel the Binge If cravings feel like a separate, uncontrollable force, it is often because they are deeply physiological, not just psychological. Our hormones and neurotransmitters play a massive role in driving emotional eating behaviors. Amber discovered this firsthand when her own extreme dieting and over-exercising pushed her into being "post-menopausal at 24." Understanding how internal chemistry becomes a primary trigger is crucial for healing. Stress and Chemical Depletion A common trigger is stress, which leads to high cortisol levels. When a person is caught in a cycle of restriction and self-loathing, the body is in a constant state of stress, which skyrockets cortisol. High cortisol doesn't just increase stress; it increases ghrelin, a hormone that makes you more hungry and causes you to feel less full more easily, often leading to a sensation described as having a "hollow leg." Furthermore, especially for women, low progesterone significantly impacts neurotransmitter levels, including lower dopamine, serotonin, GABA, and oxytocin. This leads to poor sleep and heightened sugar cravings. When this occurs, the body is not simply "craving" sugar; it is "screaming for dopamine and serotonin," and sugar is the quickest way to get that hit. The person is "depleted in dopamine and serotonin," which fuels the addiction. The Path to Root Cause Healing Understanding these deep roots is the first step toward freedom. This knowledge shifts the conversation from self-blame ("What's wrong with me?") to validation ("What's happening to me?"). The path to healing focuses on "root cause healing," which involves processing stored trauma, healing the wounded inner child, and rebalancing the hormones that push the body into panic mode. This validation—realizing that physiological and emotional pieces are fueling the problem—is very liberating, providing more answers and information for true recovery. Know that you are not alone and you are not broken. In this podcast, you'll discover: Emotional eating affects an estimated 90% of women and up to 50% of men in North America. The root causes of emotional eating are deep-seated emotional issues and powerful hormonal influences. Early childhood trauma, such as bullying, can place the body into survival mode where food provides comfort. Diet and media industries profit by conditioning insecurity and selling restrictive solutions that fuel the binge/restriction cycle. High cortisol levels caused by stress increase ghrelin, the hormone that causes persistent hunger and a feeling of being less full. Healing begins with validating the problem by shifting from self-blame to understanding the physiological and emotional triggers. EPISODE RESOURCES: Website Emotional Eating Quiz Schedule a Complimentary Body Freedom Session Podcast Amber Approved podcast Instagram
Jaume Segalés y los responsables de Mundo Natural hablan de salud y de gaba.
In this powerful episode of the Cricket Fixes Podcast, I'm joined by my dear friend and collaborator, Dr. Jennifer Rossi – an allopathically trained ER physician turned longevity and women's health specialist – to introduce our dream program:Zero for Life: The Science-Meets-Soul Method to Alcohol Freedom.We kick things off with the very modern love story of how Jen slid into my DMs, how our dogs became instant besties, and how that one message turned into a life-changing collaboration. From there, Jen shares her journey from the chaos of the emergency room to helping women thrive through perimenopause and menopause, and why she could no longer ignore what alcohol was doing to people's bodies, brains, and lives.Inside this episode, we dive into:How alcohol impacts every major organ system in the bodyThe truth about alcohol as a Class I carcinogen and its links to dementia, gut health, liver damage, hormones, and sleepWhat's really going on with dopamine, GABA, and neurotransmitters when you “just have a glass of wine”Why cravings are not just a willpower issue – they're deeply biologicalMy own story of alcohol abuse, from stealing beer at 13 to drinking 7–8 drinks a day and losing myself completelyThe cultural backlash against women choosing alcohol-free lives (hi, Self Magazine
En este episodio de Más Que Raras, tenemos el honor de contar con Agustina Fernández, una defensora incansable en el ámbito de las enfermedades raras. Agustina no solo es madre de una niña con encefalopatía genética (GABRA1), sino que también lidera como vicepresidenta y Responsable de Atención al Paciente en la fundación CURE GABA-A. Su experiencia personal se fusiona con su compromiso profesional, lo que le permite generar un impacto real en la comunidad de pacientes. En esta conversación, Agustina comparte su trayectoria como madre, enfrentando la incertidumbre del diagnóstico, las barreras del sistema y el estigma que rodea estas enfermedades. Además, nos brinda sus esperanzas y su visión para el futuro, abarcando la investigación, el acceso a terapias y el fortalecimiento de la comunidad de pacientes junto a los investigadores. No te pierdas esta charla sincera, poderosa y llena de valentía. Connect with BloodStream Media: BloodStreamMedia.com BloodStream on Facebook BloodStream on Twitter
What if your mood struggles aren't a “chemical imbalance,” but a nutrient imbalance? In this episode of The Integrative Health Podcast, Dr. Jen sits down with functional nutrition therapist Laurie Hammer, founder of the Calm Mom Method, to explore how amino acid therapy can naturally support anxiety, depression, eating disorders, focus issues, and emotional regulation.Laurie shares her personal healing journey from bulimia and lifelong depression, and explains why so many women—especially moms—are unknowingly deficient in the raw materials the brain needs to make serotonin, dopamine, GABA, and endorphins.Together, they break down how targeted amino acids can bring fast relief, how to test your own neurotransmitter needs, and why rebuilding the brain's chemistry through nutrients is often more effective than relying on medications alone.Dr. Jen and Laurie Hammer discuss amino acid therapy as a natural approach for anxiety, depression, and emotional instability. Learn how nutrient deficiencies impact neurotransmitters and how targeted amino acids can restore mood, focus, and calm.
TJ kicks off the show giving a recap of the Radio Thon last Thursday and Friday, then he also gives an NFL, and UNM Lobos recap. During this hour Gaba gives one of his all time zingers. Lastly Adrian Perez COO of Heritage Companies, and Raquel Chambers, Director of the NM Artisan Market at Old Town join TJ. All on News Radio KKOBSee omnystudio.com/listener for privacy information.
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The fascinating intersections of circadian biology, quantum health, and women's wellness really come alive as I sit down with Neurosurgeon-turned-Quantum-Biologist Dr. Jack Kruse. You'll hear how simple things, like the light you see first thing in the morning, quietly shape your hormones, energy, and even how you age. Dr. Jack's decades of surgical and biophysical knowledge make these concepts surprisingly practical for everyday health. By the end, you may find yourself rethinking your daily routines in the best way. Together, we get into why AM sunlight can make such a big difference for women going through hormonal changes, especially around menopause. Dr. Jack breaks down big ideas like heteroplasmy in simple, eye-opening terms and shows how it plays into skin health, longevity, and mitochondrial function. You'll also hear why red light deserves a place in your wellness routine, and how blue light and non-native EMFs might be draining more than just your battery. If you've ever struggled with weight changes, low energy, or hormonal shifts, you'll appreciate Dr. Jack's explanation of the leptin-melanocortin pathway and what it means for women at every age. His own 150-pound weight-loss story adds real heart to the science and shows how much can change when your environment starts working for you instead of against you. This episode delivers a mix of empowering insights and simple shifts you can start today for better vitality. And before you go, make sure to download my Free Holiday Recipe Guide, a delicious, hormone-friendly way to enjoy festive, Keto-Green dishes all season long at dranna.com. Key Timestamps: [00:00:00] Introduction. [00:04:57] Circadian biology and health optimization. [00:10:10] The importance of morning sunlight. [00:17:00] Environmental impact on women's health. [00:19:54] Blue light toxicity in eyes. [00:23:04] Impact of sunglasses on health. [00:27:52] Importance of oxytocin hormone. [00:30:30] Mitochondria and light absorption. [00:36:15] Leptin and fertility connection. [00:38:05] Importance of fat for babies. [00:43:05] Blue light's role in hormonal balance and infertility. [00:45:36] Natural sun protection alternatives. [00:50:32] Hormonal health and technology impact. [00:53:10] Light as medicine and healing. [00:58:41] GABA and benzodiazepine addiction. [01:00:06] Relationship between light and health. [01:09:18] Deuterium's impact on health. [01:13:39] Sun exposure for sexual health. [01:20:34] Politics and health care challenges. [01:24:03] Importance of time over wealth. [01:27:29] Jet lag management strategies. Memorable Quotes: "If you're a woman who's a dried-up prune, this by definition already tells you that you don't get enough AM sunlight." [00:10:17] – Dr. Jack Kruse "Blue light is the single number one thing that destroys hormone balance." [00:43:21] – Dr. Jack Kruse Links Mentioned: Free Holiday Recipe Guide: https://dranna.com/holidayrecipes Connect with Dr. Jack Kruse: Website: https://jackkruse.com/ Instagram: https://www.instagram.com/drjackkruse/ Facebook: https://www.facebook.com/drjackkruse/ Patreon: https://www.patreon.com/drjackkruse Connect with Dr. Anna Cabeca: Website: https://drannacabeca.com/pages/show Instagram: https://www.instagram.com/thegirlfrienddoctor/ YouTube: https://www.youtube.com/@thegirlfrienddoctor TikTok: https://www.tiktok.com/@drannacabeca Produced by Evolved Podcasting: www.evolvedpodcasting.com
Ready for Radiothon? TJ will be out Thursday and Friday to help collect food donations and monetary contributions for Roadrunner Food Bank, and we all hope you can help out with what you can. He also does his Weekly World News roundup, and talks to Gaba about people "being courteous". All this and more on News Radio KKOBSee omnystudio.com/listener for privacy information.
4th at Olympia 2025, 5th at Olympia 2025, & Prague Pro ChampThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program: https://www.nylenaygafitness.comTimestamps:00:00:00 Intro00:10:13 Sleep Stack: Melatonin, GABA, L-Theanine00:16:34 Pittsburgh Pro Miss & Mental Reset00:20:36 Olympia Flatness vs. Prague Peak00:25:12 Prague Peak Recipe Perfection00:31:10 Olympia Migraine Backstage00:35:23 Earlier Hammer Drop (6 Weeks Out)00:40:20 Strict Salt/Water Tracking (10g/5L)00:44:49 Pulling Test Early in Open vs. Classic00:53:18 Yo-Yo Feeding Strategy01:00:36 TB-500 & BPC-157 for Injuries01:04:47 Winstrol Sides & Inflammation01:10:16 Blue Collar to Pharmacy Journey01:18:23 Beating 5 Mr. Olympia Champs01:24:49 Data-Driven Confidence01:34:29 Anti-Shrink Secrets01:36:48 Slow Gains, Max Detail01:44:41 Videographer Coop Magic01:47:18 Cream of Rice Hack01:51:17 Water Retention Balance01:55:24 Fat-Holding Edge02:01:03 Lean Protein Choices02:03:21 Muscle Fatigue Battles02:08:00 X-Frame Strategy02:11:14 Dehydration Balance02:12:47 Parabolan PED Vibes02:15:21 Bloodwork Monitoring02:20:03 Insulin Off-Season Use02:23:01 Insulin & Cardio Effects02:27:00 Insulin & Blood Pressure02:30:00 Insulin & Test Levels02:33:30 Glutamine GI Benefits02:36:45 Tips for Sport Success02:40:56 Grateful for Bodybuilding02:44:33 Journey Support Thanks
If you're parenting an Autistic child and living in a state of constant alert (sensory overwhelm, dysregulation, sleepless nights, meltdowns, and the never-ending to-do list), this episode gives you a concrete biochemical map for how to get back to baseline. In today's conversation,I'm joined by Dr. Scott Sherr board certified internal medicine physician, certified practitioner of Health Optimization Medicine, and COO of Troscriptions, a company making physician formulated, precision-dosed buccal troches for focus, stress, sleep, and immune function. We talk about: What is the "sympathetic spiral of doom." What GABA deficiency actually looks like (and why calming down isn't as simple as "go meditate"). Why mitochondrial dysfunction and chronic inflammation show up so strongly in autistic and disabled kids and how supporting cellular energy can actualy reduce hyper-excitability. The real problem with giving kids 10–20 supplements at once. How targeted support can help caregivers feel better now, while they work the longer game of diet, lifestyle, and environment. Links Mentioned Dr. Scott Sherr's clinical practice: https://drscottsherr.com Troscriptions Products: https://troscriptions.com (Please work with a practitioner before using any product with a child.) If you found this episode helpful: Please share it with a caregiver who feels stuck in stress, burnout, or dysregulation. And grab my free guide: Gut Health Toolkit
In today's episode, I'm diving into a topic I've been thinking about a lot lately: the deep relationship between our nervous system, endocrine system, and digestive system—and how these three powerful systems work together to shape our mood climate.We often talk about emotions as if they are our mood, but they're not the same. Emotions come and go like shifting weather patterns, while mood is more like the long-term climate of our inner world. In this video, I explore what actually influences our mood, how our physiological systems interact, and why understanding this triad can give us more tools for emotional regulation, mental health, and overall well-being.I also share why the choices we make in the heat of an emotional moment can shape our longer-term mood, and how becoming aware of these patterns can help us cultivate more stability, resilience, and self-understanding.We will focus on three adaptogens which specifically address the mood triangle:- Rhodiola- Tulsi- SchisandraIf you've ever wondered why your mood lingers long after an emotion has passed, or how your body's internal systems contribute to how you feel day after day, this conversation will give you a clearer, more empowered perspective.
In today's episode, Gina shares her wisdom surrounding the topic of menopause, perimenopause and how these times can bring with them substantial shifts in women's nervous systems. Many women experiences substantial changes in their experience of anxiety around this midlife change, some for better, some for worse. The physiological changes of the body and brain are discussed, as are the mental changes that accompany them, and also the steps you can take to support yourself through this journey. Improve your understanding of menopause and it effects on anxiety today!Please visit our Sponsor Page to find all the links and codes for our awesome sponsors!https://www.theanxietycoachespodcast.com/sponsors/ Thank you for supporting The Anxiety Coaches Podcast. FREE MUST-HAVE RESOURCE FOR Calming Your Anxious Mind10-Minute Body-Scan Meditation for Anxiety Anxiety Coaches Podcast Group Coaching linkACPGroupCoaching.comTo learn more, go to:Website https://www.theanxietycoachespodcast.comJoin our Group Coaching Full or Mini Membership ProgramLearn more about our One-on-One Coaching What is anxiety? Find even more peace and calm with our Supercast premium access membership:For $5 a month, all episodes are ad-free! https://anxietycoaches.supercast.com/Here's what's included for $5/month:❤ New Ad-Free episodes every Sunday and Wednesday❤ Access to the entire Ad-free back-catalog with over 600 episodes❤ Premium meditations recorded with you in mind❤ And more fun surprises along the way!All this in your favorite podcast app!Quote:Mid-life is when a woman awakens to her power; not the power of youth, but the power of depth.Chapters0:26 Introduction to Hormonal Changes3:12 Understanding Anxiety in Midlife6:35 Hormonal Shifts and Their Effects8:10 Supporting Your Nervous System10:18 Lifestyle Changes for Balance13:17 Emotional Layers of Midlife17:22 Identity Transition and Self-Discovery18:19 Embracing the Journey AheadSummaryIn this episode of the Anxiety Coaches Podcast, I delve into an important and often overlooked topic: the hormonal changes that women undergo during midlife and how these shifts can intricately weave into experiences of anxiety. As we explore this vital subject, I emphasize the uniqueness of each individual's journey through hormonal shifts, whether during perimenopause, menopause, or even monthly cycles. Recognizing the natural ebb and flow of hormonal changes, I reassure listeners that they are not "broken" or "losing it"—rather, their bodies are in a transformative phase, prompting a deeper understanding and connection to self.I lay the foundation by discussing the physiological impacts of fluctuating hormone levels and outline how these changes can manifest as various emotional and physical sensations. The transition can trigger new feelings of anxiety, identity crises, and insights into how one's life roles have evolved. It's essential to approach these transitions with curiosity, as understanding the interplay between hormones, stress, and emotional well-being can empower women during this compelling time.Commencing with an intimate exploration of the effects of estrogen and progesterone, I highlight how these hormones influence mood and anxiety levels. Listeners are encouraged to recognize that increased anxiety during these transitions is not a sign of weakness but rather a normal physiological response. I present practical strategies for self-care, including breathing techniques and grounding exercises, to help ease anxiety and cultivate a nurturing relationship with oneself. By advocating for slow exhale breathing, comforting mantras, and gentle physical practices, I offer tools that can aid women in navigating this sensitive phase with grace.#Perimenopause, #Menopause, #MidlifeAnxiety, #HormonalAnxiety, #WomensHealth, #TheChangeOfLife, #AnxietyRelief, #MidlifeTransition, #Recalibration, #IdentityShift, #Estrogen, #Progesterone, #NervousSystem, #StressManagement, #PrioritizeSleep, #SelfCare, #SetBoundaries, #GABA, #SlowExhale, #YouAreNotBroken, #GinaRyan, #AnxietyCoachesPodcast, #ChristianeNorthrup, #FemininePower, #NotLosingIt, #AnxietySupport, #MentalWellness, #StressRelief, #MindBodyConnection, #LifeTransitions, #SelfCompassion, #NervousSystemRegulation, #EmotionalHealth, #HealthJourney, #PersonalGrowth, #SelfHelp, #InnerPeace, #Midlife, #HormoneHealth, #WellbeingJourney, #DeepBreathing, #GroundingTechniques, #MentalClarity, #Recalibration, #ItsOkayToStruggle, #FindingYourCenter, #PodcastForAnxiety, #AuthenticSelf, #ChangingRhythms #ACPSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
On this episode of Vitality Radio, Jared dives deep into one of the most fascinating frontiers in functional nutrition—brain energy. He unpacks how ATP fuels your mind, why BDNF acts like “fertilizer for neurons,” and how lifestyle stressors, toxins, and poor sleep can dim your mental lightbulb. From there, he explores the natural tools that can reignite focus, memory, and long-term cognitive vitality. You'll hear how powerhouse nutrients can support mitochondrial performance, boost brain-derived neurotrophic factor, and promote sharper thinking—without the crash of caffeine or pharmaceuticals. Jared wraps up with three practical, results-driven protocols: one for focus and ADHD support, one for immediate memory and cognition, and one for long-term prevention of cognitive decline. Each stack can be customized to fit your individual goals so you can think clearer, focus longer, and age smarter—naturally.Brain Boosting Protocol CollectionShop the collection! Bundle and save - no code needed, just add to your cart to get:Buy 2 at 10% offBuy 3-4 at 15% offBuy 5+ at 25% offAdditional Information:Brain Boosting Protocol Blog Post#335: The Latest Research on Preventing and Reversing Dementia and Alzheimer's with Dr. Dale Bredesen#570: Liquid Yoga & Mind Fuel: Harnessing Mushrooms and Herbs for Focus and Calm#511: Unraveling NAD+ and NMN for Longevity and Anti-AgingVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
Alcohol is the world's most socially accepted toxin — a substance woven into our rituals, relationships, and celebrations, yet responsible for immeasurable physical, emotional, and societal harm. What happens when we finally confront that truth?In this episode, we sit down with Professor David Nutt, neuropsychopharmacologist, author, and founder of GABA Labs, to explore alcohol's hidden toll on the human terrain — from cellular toxicity and neuroinflammation to cultural indoctrination and addiction.David explains how alcohol damages nearly every system in the body, why our governments and industries continue to protect it, and how his groundbreaking work is offering a path forward. Through Sentia, a functional, non-alcoholic alternative designed to replicate alcohol's social and relaxing effects without the poison, David and his team are reimagining what it means to connect, unwind, and celebrate — consciously.We discuss:Why alcohol remains the most harmful drug in Western societyThe biological and social mechanisms behind addictionHow alcohol reshapes the terrain at every level — from the liver to the mindThe emerging movement toward functional, toxin-free social drinkingSentia, GABA Labs, and the future of conscious convivialityListen in as we uncover the paradox of the terrain toxin we celebrate — and the promise of a future beyond it.Learn more about Dave and his work at: https://gabalabs.com.Learn more about Sentia at http://www.sentiaspirits.com/ and follow them on Instagram at https://www.instagram.com/sentiaspirits/.Support Terrain Theory on Patreon! Our recently-launched member platform gives you access to a ton of free & exclusive content. Check it out: https://www.patreon.com/TerrainTheoryHelp support Ryan and Briana's road to recovery by donating to our GoFundMe set up in their name. Every penny will go to cover the costs of associated with healing their terrain using alternative, terrain-friendly methods. Donate here: https://www.gofundme.com/f/help-ryan-briana-heal-from-pfas-exposureTerrain Theory episodes are not to be taken as medical advice. You are your own primary healthcare provider.If you have a Terrain Transformation story you would like to share, email us at ben@terraintheory.net.Learn more at www.terraintheory.netFollow Terrain Theory:Instagram: https://www.instagram.com/terrain_theory/Facebook: https://www.facebook.com/Terrain-TheoryX: https://twitter.com/terraintheory1YouTube: https://www.youtube.com/@terraintheoryMusic by Chris Merenda
What if the reason connection feels so hard isn't about willpower or awareness—but about your brain literally not getting the dopamine reward that makes relationships feel joyful and worth pursuing? In this mini episode, Dr. Aimie Apigian dives into groundbreaking 2009 research that revealed something shocking: mothers with insecure attachment showed almost no dopamine response to their own babies' faces—whether smiling or crying. This isn't about not loving their children; it's about their brains not experiencing the biological reward that makes caregiving feel naturally joyful. This episode explores why attachment rupture and addiction are so deeply connected (hint: they're both about dopamine), how your attachment style literally changes your brain's reward response to connection, and most importantly—what you can do about it at the biological level. In this episode you'll hear more about: The dopamine discovery: How the 2009 brain imaging study revealed that insecurely attached mothers showed almost no dopamine response to their own babies, while securely attached mothers had robust reward center activation Why connection feels hard: Understanding that dopamine is the "meaning-making" neurotransmitter that says "this is good, do this again"—and without it, authentic connection doesn't bring the same sense of joy or motivation The attachment-addiction link: Why addictions are fundamentally about managing dopamine, and how attachment rupture creates the same dopamine dysregulation that drives addictive patterns The blunted response reality: What it actually means when a mother doesn't get the dopamine hit from her baby's face—she's fighting her own biology to find joy in caregiving, making everything feel harder than it should The ripple effect beyond parenting: How insecure attachment creates a blunted dopamine response to ALL authentic relationships, not just with children—affecting your capacity for joy in connection throughout your life The neurotransmitter soup: How dopamine interfaces with oxytocin (the bonding neurotransmitter and stress reducer), serotonin, endorphins, and GABA to create the biology of attachment Why talking isn't enough: The critical understanding that we must repair attachment at the biology level, not just through awareness—otherwise we're literally fighting against our own neurotransmitter systems Dr. Aimie's personal biology: Her vulnerable sharing about being born with undermethylation, creating naturally lower serotonin and dopamine activity from birth, making her nervous system less available for bonding The practical repair toolkit: How to support dopamine production through tyrosine (the amino acid building block for dopamine) and DL-Phenylalanine (the gentler option for sensitive systems) The cofactor support: Why B6 and magnesium are essential nutrients your body needs to actually make dopamine from these building blocks The root cause approach: How supporting undermethylation with SAM-e helped Dr. Aimie change her epigenetics and eventually get off two mood medications by addressing the biology underneath The biochemical imbalances: Why the same three biochemical imbalances show up in both stored trauma and attachment insecurities—and how to assess your own biology Your attachment style isn't just psychological—it's biological. When we understand that insecure attachment creates measurable changes in neurotransmitter responses, we can stop blaming ourselves for why connection feels so hard and start addressing the root cause. The good news? Your biology can change.
Today, I'm thrilled to welcome Dr. Amy Killen, a visionary in hormone optimization and regenerative medicine who is transforming the conversation around women's health and longevity. In this episode, Dr. Killen shares her personal journey—from witnessing her mother's struggle after a hip fracture, to becoming a steadfast advocate for correcting the myths and misinformation that still surround estrogen, progesterone, and testosterone optimization. Episode Timestamps: Ferritin, iron, and hormonal health basics ... 00:00:43 Dr. Amy Killen's evolving hormone focus ... 00:04:02 Women's Health Initiative and estrogen myths ... 00:06:31 Importance of hormone optimization vs. stem cells ... 00:10:25 Testosterone for women: symptoms, labs, delivery options ... 00:12:05 Side effects and nuances of testosterone therapy ... 00:14:01 SHBG, free testosterone, and lab variability ... 00:16:38 Libido, PT-141, and the biopsychosocial lens ... 00:21:46 Iron and ferritin: sweet spot and skin implications ... 00:29:16 Hot vs. HRT: definitions and individualization ... 00:34:23 Debunking estrogen and breast cancer myths ... 00:41:30 Aging expectations and finding the right doctor ... 00:43:18 Advice for women by decade—20s, 30s, 40s, etc. ... 00:47:20 Our Amazing Sponsors: Tro Zzz by Troscriptions - This isn't just melatonin—it's a powerhouse! Oblipair gives you honokiol and agarin to enhance GABA binding, while adenosine and cordycepin boost sleep drive and deep sleep. CBD, CBN, and 5‑HTP round it out. Head to troscriptions.com, use NAT10, and get 10% off your first order. NMN+G Rx by Wizard Sciences - A scientifically formulated blend of NMN, ginsenosides from Panax ginseng, and apigenin. Together, they enhance mitochondrial function, boost NAD+ levels, and support cellular repair. Go to wizardsciences.com and look for NMN+G. Use code NAT15 at checkout to get 15% off your purchase. Probiotic Breakthrough by Bioptimizers: uses a stress-tested Lactobacillus plantarum strain that showed over 30× greater survival in bile and intestinal fluid vs. generic strains. Save 15% at bioptimizers.com/bionat and use code BIONAT for 15% off any order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
Board-certified internal medicine physician and health-optimization specialist Dr. Scott Sherr talks about parenting with presence, nervous-system regulation, mitochondrial health, and when methylene blue actually makes sense. We get practical about small, sustainable changes (especially for exhausted parents), alcohol and GABA, and why looking at your "holobiont" beats one-size-fits-all wellness. Listen if you want practical, parent-friendly strategies to protect your energy, model healthy habits for your kids and partner, and create a calmer baseline before relying on tech or supplements. WE TALK ABOUT: 05:00 - What "health optimization" really means vs. disease care 08:10 - Balancing work, partnership, and nervous-system regulation 12:35 - Sustainable micro-habits that stick 15:15 - Small changes that create big impact 17:30 - Alcohol, GABA, and the slippery slope of "relaxation" 23:05 - Methylene blue 101 and why mitochondria matter 36:15 - The holobiont lens: Optimize the whole "you," not just symptoms 44:20 - Can we actually measure mitochondrial function yet? 46:40 - When and how to use methylene blue for energy + calm SPONSORS: Feeling bloated, tired, or hormonally off? Try BiOptimizers — supplements that actually absorb and work for women's health. Get 15% off at bioptimizers.com/biohackingbrittany with code BIOHACKINGBRITTANY. Join me in Costa Rica for Optimize Her, a 5-night luxury women's retreat in Costa Rica with yoga, healing rituals, and biohacking workshops—only 12 spots available. RESOURCES: Trying to conceive? Join my Baby Steps Course to optimize your fertility with biohacking. Free gift: Download my hormone-balancing, fertility-boosting chocolate recipe. Explore my luxury retreats and wellness events for women. Shop my faves: Check out my Amazon storefront for wellness essentials. Dr. Scott Sherr's website and Instagram LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music
Why do so many women feel anxious, tired, or off balance at certain times of the month? In this episode, Angela and Dr. Sarah Hill explore how changes in estrogen and progesterone affect mood, focus, and energy, and what happens when stress, inflammation, or birth control disrupt that rhythm. You'll learn how hormones influence sleep, stress response, and emotional well-being, how to identify if you're not ovulating regularly, and how to support your hormones naturally. If you've ever wondered, “Why do I feel different at different times in my cycle?” - this episode gives you the answers. What You'll Learn: • What progesterone really does • Why anxiety increases before your period or in perimenopause • How stress and inflammation affect your hormones • Why many women don't ovulate every month • The link between birth control, alcohol cravings, and mood • Progesterone vs. synthetic progestins • Why teens and women in perimenopause experience similar symptoms • Why women's health research needs to change • How to track your cycle and hormones TIMESTAMPS 00:00 – Intro & Why Hormones Drive How Women Feel 03:00 – The Menstrual Cycle Explained 08:00 – How Progesterone Calms the Brain 12:00 – PMS, PMDD & Hormonal Sensitivity 17:00 – Inflammation, Stress & Hormonal Resilience 23:00 – Lifestyle Shifts that Restore Balance 33:00 – Long Cycles, Bleeding & Birth Control 36:00 – PCOS, Mental Health & Progesterone 43:00 – Progestins vs. Progesterone 47:00 – Alcohol, GABA & Stress Relief 49:00 – Supporting Hormones in Perimenopause 50:00 – Teenage Hormonal Turbulence 57:00 – Investigating Cycle Issues 1:00:00 – Why Science Still Gets Women Wrong 1:08:00 – Hormones, Training & Recovery WATCH my previous interview with Dr. Sarah Hill through this link: https://youtu.be/z9sfph-9_MA VALUABLE RESOURCES A BIG thank you to our sponsors who make the show possible: - Defender Shield - http://defendershield.com/ANGELA | Use the code ANGELA at checkout for an exclusive 10% off - Supercharge your energy and upgrade your mitochondria with Mitopure - http://timeline.com/angela | Enter code ANGELA to save 10% - Quantum Upgrade - http://quantumupgrade.io/ | Use code ANGELA15 to get your 15 day free trial. No credit card required ABOUT THE GUEST Dr. Sarah E. Hill is an award-winning researcher, professor, and author of This Is Your Brain on Birth Control. Her new book, The Period Brain, is due out in September. - Website: http://www.sarahehill.com/ - This Is Your Brain on Birth Control: https://a.co/d/4UkgnQg - The Period Brain: https://www.sarahehill.com/books/the-period-brain/ - Facebook: https://www.facebook.com/sarahehillphd2 - Instagram: https://www.instagram.com/sarahehillphd/ - Twitter: https://x.com/sarahehillphd ABOUT THE HOST Angela Foster is a Nutritionist, Health & Performance Coach, and host of the High Performance Health podcast. A former corporate lawyer turned biohacker, Angela helps women optimize energy, hormones, and longevity through her BioSyncing® framework. DISCLAIMER The High Performance Health Podcast is for informational purposes only and does not constitute medical or coaching advice. Always seek guidance from your healthcare professional before making changes to your health routine. This Podcast has been brought to you by Disruptive Media - https://disruptivemedia.co.uk/
My guest today is Dr. Hector — a psychiatrist who specializes in helping people heal from addiction, PTSD, anxiety, and depression through a trauma-informed approach. He blends neuroscience, medication, and therapy with nutrition and lifestyle tools to support whole-person healing. What I love about his work is that it's not just clinical — it's deeply compassionate. He helps people understand how their brain and body work together so they can build resilience, recover from addiction, and truly heal from the inside out. He shares why most people relapse not because of willpower, but because trauma remains unresolved. From the role of GABA in calming the nervous system to how EMDR helps reprocess trauma, this episode is packed with practical tools and compassionate wisdom for anyone on the healing path. Before we jump in, I have a new segment, called “A question for you!” Today I want to know how you feel about the word “Alcoholic”. I was interviewed on another podcast today and the host told me he thought it was a shame label. If you know me even a little bit, you'll know that the way I define it - it's a badge of honor, but also, it doesn't matter to me what you call yourself, as long as you get the support you need to heal and break free from addiction. So what do you think? Leave your comment under this episode at odaatchat.com Or leave a comment on my Instagram: @arlinaallen Next week I'll share some of your responses! Be sure to subscribe so you don't miss out. And with that, please enjoy this episode with Dr Hector. Guest Contact Info: doctorhector.com
Many women enter perimenopause unprepared for the brain remodeling and nervous system changes that make this transition feel destabilizing. For practitioners supporting clients through midlife, and for women navigating perimenopause themselves, understanding how stored trauma amplifies symptoms and shrinks capacity changes everything about this journey. This episode features Dr. Mariza Snyder, author of The Perimenopause Revolution, who shares her personal journey through perimenopause while carrying complex PTSD from childhood abuse. You'll discover why stabilizing blood sugar becomes foundational for cellular energy, how the critical line of overwhelm shifts during perimenopause, and why brain inflammation during this transition feels like cognitive decline. Dr. Mariza reframes perimenopause as an invitation to review what's up for change—relationships, obligations, and patterns that no longer serve your nervous system—rather than something to survive. In this episode you'll learn: 02:16 Why Blood Sugar Stability Is Pillar One: How stabilizing cellular energy through food becomes foundational during perimenopause and nervous system dysregulation 04:30 Perimenopause as Neuroendocrine Transition: Understanding neuroinflammation and brain remodeling during erratic hormone decline 08:14 When Executive Function Falters: Why women who effortlessly managed 100 tabs suddenly can't multitask the way they used to 11:22 Change and Stored Trauma: Why perimenopause triggers those carrying trauma—change means the unknown, and the unknown feels more dangerous than familiar suffering 14:18 Everything Up for Review: How perimenopause forces discernment about what you've been tolerating, prioritizing, and saying yes to 17:03 The Critical Line of Overwhelm Shifts: How perimenopause shortens your capacity threshold and why that might be the invitation you need 20:53 The Cake Pop Phenomenon: Why women operate disconnected from their bodies and how perimenopause demands new attunement 23:14 Progesterone, GABA, and Melatonin Decline: The alarming rate at which women lose these calming neurochemicals during perimenopause 27:09 Shifting State Through Grounding: Practical strategies like naming objects in the room to get prefrontal cortex online 28:34 The Five Week Midlife Reset Plan: Movement, sleep strategies, meal plans, recipes, and symptom trackers to create wins without overwhelm Main Takeaways: Cellular Energy Determines Everything: Blood sugar stability creates homeostasis that supports mood regulation, stress tolerance, and nervous system capacity—making it foundational for both perimenopause and trauma healing. Perimenopause Shrinks Your Critical Line of Overwhelm: Your capacity threshold shortens during perimenopause, forcing discernment about relationships, obligations, and patterns that push you over the edge into dysregulation. Brain Inflammation Mimics Cognitive Decline: The erratic decline of estrogen, progesterone, GABA, and melatonin creates neuroinflammation that feels like early dementia but is actually your brain remodeling for the second half of life. The Hundred-Tab Brain Stops Working: Executive function that allowed effortless multitasking begins to falter—it's a time your brain is recalibrating to focus on one thing at a time. Stored Trauma Amplifies Perimenopause Symptoms: Women with childhood trauma, hypervigilant nervous systems, and complex PTSD experience perimenopause as more destabilizing because change triggers survival responses rooted in the unknown feeling dangerous. Everything Comes Up for Review: Perimenopause forces examination of what you've been tolerating—work obligations, relationships, people-pleasing patterns, and the habit of prioritizing everyone else before yourself. Disconnected Demands New Attunement: Operating disconnected from your body (all cerebral, nothing below the neck) no longer works—perimenopause demands you drop into your body and form new relationships with its signals. Notable Quotes: "If we could just optimize, stabilize our cellular energy through stabilizing our blood sugar, we really set a great foundation." "We could have a hundred tabs open and manage them effortlessly. And then I remember the day where I was really having to effort because that level of executive function begins to falter." "Nothing is wrong. Stop trying to find something to do right now. Like, just be present in the moment." "I feel like a cake pop sometimes. Everything is just happening here and what's below my head, there's nothing below. You know, I'm so disconnected." "Perimenopause is a time for discernment, because everything is up for review. We get to work on the trauma because it's probably coming up for review." "The critical line of overwhelm—you have less of a line. It shortens. And I don't necessarily think that that is a bad thing if you can become aware." Episode Takeaway: Perimenopause isn't just about hot flashes and missed periods. Your brain is literally remodeling itself. Hormones that showed up predictably for decades now arrive erratically. For women carrying stored trauma, this feels destabilizing. Change means the unknown. The unknown feels dangerous. You don't know who you're becoming. You don't know what your capacity will be. You don't know if you can trust your brain anymore. Your nervous system responds the only way it knows how—by staying on alert. The critical line of overwhelm shifts during perimenopause. Your capacity threshold shortens. What felt manageable last year now pushes you over the edge. The relationships that drain you. The obligations you never wanted. The people-pleasing patterns you've carried for decades. They suddenly feel intolerable. Your nervous system no longer has bandwidth for what doesn't serve you. Stabilizing cellular energy through blood sugar becomes foundational because dysregulation multiplied by time creates the neuroinflammation that mimics cognitive decline. Women who operated as "cake pops"—all cerebral, disconnected from body signals—discover that perimenopause demands new attunement. Your body is no longer willing to be ignored. The invitation is to grieve your former self, accept your brain's recalibration, and choose what you're calling into the second half of your life with fierce discernment about what matters enough to maintain your nervous system regulation. Resources/Guides: The Perimenopause Revolution by Dr. Mariza Snyder - The comprehensive manual for navigating perimenopause with nervous system support, blood sugar strategies, movement plans, meal plans, and the five-week midlife reset. Get the book and access over $700 in bonuses at drmariza.com/book The Biology of Trauma book - Available now everywhere books are sold. Get your copy Foundational Journey - If you are ready to create your inner safety and shift your nervous system, join me and my team for this 6 week journey of practical somatic and mind-body inner child practices. Lay your foundation to do the deeper work safely and is the pre-requisite for becoming a Biology of Trauma® professional. Related Episodes: Ep 166: The Body Keeps Score: How Trauma Rewires Your Nervous System with Dr. Bessel van der Kolk Ep 123: Light, Sleep and High-Impact Habits To Heal Your Nervous System Guest: Dr. Mariza Snyder is a functional practitioner and author of The Perimenopause Revolution, the comprehensive guide helping women navigate perimenopause with nervous system regulation, cellular energy optimization, and practical strategies for the decade-long transition. With her own experience of complex PTSD and hypervigilant nervous system, she brings both clinical expertise and personal understanding to supporting women through midlife brain remodeling. Learn more at drmariza.com and connect with her on Instagram @drmariza. Your host: Dr. Aimie Apigian, double board-certified physician (Preventive/Addiction Medicine) with master's degrees in biochemistry and public health, and author of the national bestselling book "The Biology of Trauma" (foreword by Gabor Maté) that transforms our understanding of how the body experiences and holds trauma. After foster-adopting a child during medical school sparked her journey, she desperately sought for answers that would only continue as she developed chronic health issues. Through her practitioner training, podcast, YouTube channel, and international speaking, she bridges functional medicine, attachment and trauma therapy, facilitating accelerated repair of trauma's impact on the mind, body and biology. Disclaimer: By listening to this podcast, you agree not to use this podcast as medical, psychological, or mental health advice to treat any medical or psychological condition in yourself or others. This podcast is for informational and educational purposes only and does not constitute professional advice, diagnosis, or treatment. Always consult your own physician, therapist, psychiatrist, or other qualified health provider regarding any physical or mental health issues you may be experiencing. Comment Etiquette: I would love to hear your thoughts on this episode. Please share and use your name or initials so that we can keep this space spam-free and the discussion positive
Fuel Her Awesome: Food Freedom, Body Love, Intuitive Eating & Nutrition Coaching
Episode 2: The Mental Side of Estrogen & Progesterone Your hormones don't just shape your cycle—they shape your mind. In this episode, we're digging into how estrogen and progesterone impact mood, memory, motivation, and mental health, and what you can do about it. Book an intake with Jess! Learn more about Empowered Eating HERE! What You'll Learn in This Episode 1. How Estrogen & Progesterone Affect the Brain Estrogen boosts serotonin and dopamine, supporting mood, memory, and cognition. Low levels? Think irritability, brain fog, mood swings, and focus struggles. Progesterone has calming, GABA-like effects that regulate anxiety and sleep. When levels dip, anxiety and insomnia often spike. Fluctuations (like PMS or perimenopause) create emotional reactivity—and some women are more sensitive than others. 2. Why This Feels So Hard Cyclical mood swings, irritability, and brain fog PMS and PMDD challenges Perimenopause mood dysregulation and midlife depression risk Sleep disruptions that worsen mood and focus 3. The “ALIFE” Framework (Episode 1 Refresher) A – Adapt Stress: Cortisol throws hormones off rhythm. L – Love Your Liver: Cruciferous veggies + hydration help clear excess hormones. I – Increase Awareness: Track your cycle and mood, sleep, energy. F – Fuel for Balance: Protein, fiber, and healthy fats stabilize blood sugar. E – Embrace Sleep: Non-negotiable for hormone harmony. 4. Actionable Strategies from a Clinical Perspective Track & Monitor with Intention: Chart mood, cravings, sleep, and energy with your cycle to spot patterns. Micronutrients that Matter: Omega-3s (EPA/DHA) → serotonin support B vitamins (especially B6) → neurotransmitter synthesis Magnesium → calms the nervous system & eases PMS irritability Tryptophan → serotonin precursor (turkey, eggs, nuts) Iron & Zinc → energy, brain clarity, progesterone support Balancing Estrogen: Boost when low: phytoestrogens (flax, soy), adequate calories, micronutrients Bind excess when high: cruciferous veggies, fiber, probiotics for gut health Lifestyle Levers: Balance blood sugar → stable mood Manage stress → keep cortisol from hijacking sex hormones Move daily → serotonin boost & hormone metabolism Prioritize sleep → keeps the whole hormone orchestra in sync 5. When to Ask for Help If mood swings, anxiety, or depression become debilitating or interfere with daily life, it's time to bring in professional mental health support alongside nutrition and lifestyle strategies. Key Takeaway You don't have to be at the mercy of your hormones. With the right nutrition, awareness, and lifestyle tools, you can work with your cycle instead of fighting against it. This is Empowered Eating in action: where science, biofeedback, and your values intersect so you can feel like yourself again.
In this episode of the Beautifully Broken Podcast, I'm joined by Aleena Kanner, a certified athletic trainer, neuromuscular specialist, and breathwork educator, for a deep dive into the biomechanics of healing. Aleena breaks down how subtle shifts in the jaw, teeth, and eyes can create—or resolve—chronic pain patterns. We explore how asymmetries in the body reflect deeper imbalances in the nervous system, and how restoring balance can be the key to sustainable healing.Aleena shares her personal health story—from eczema and autoimmune challenges to Olympic weightlifting and nervous system dysregulation—and how her journey informed the way she works with clients today. She also opens up about her experience with PRP for hair restoration, what worked, and what she'd do differently.We wrap with powerful takeaways on movement, posture, and reclaiming sovereignty over your health by understanding the body's asymmetrical brilliance. Episode Highlights[00:00] – How bite and dental occlusion influence facial asymmetry and pain[01:26] – Aleena's morning rituals: boardwalk walks, red light, sauna, and breath[03:41] – What is the Avant laser? Laser therapy and mitochondrial function[06:22] – The danger of impulse purchases in wellness[08:12] – Aleena's definition of her work: neuromuscular science and sensory integration[10:19] – How she assesses the body: gait, breath, facial symmetry, and range of motion[13:44] – Understanding the “squinty eye” and cranial bone misalignments[16:10] – Freddie shares his craniosacral breakthroughs and insomnia recovery[18:01] – Dental appliances, bite patterns, and their effect on grip strength[22:11] – Asymmetry and neurological disease: the overlooked root causes[24:37] – Scoliosis, breathing dysfunction, and healing without bracing[26:52] – The walking wounded and healing from mold, Lyme, and trauma[31:36] – Where to find real help: vetting providers, PRI, and Aleena's free resources[36:39] – The lymphatic system's asymmetry and the brilliance of our design[38:40] – Aleena's birth trauma and lifelong nervous system healing[41:07] – The Olympic weightlifting years, hormonal crash, and recovery[44:02] – Genetics, sensitivity, and the danger of GABA and LDN[46:13] – Navigating the Wild West of functional medicine[48:07] – PRP therapy for hair: emotional release, pain, and real results[53:00] – Hair recovery protocol tips and red light therapy[55:07] – Co-creating a hair recovery course + holistic aftercare[57:25] – What it means to be beautifully broken: resilience through difficulty[59:26] – Aleena's #1 tip for posture and nervous system health: go walk and swing your arms Connect With Aleena– Aleena Kanner's Free Shoe Guide + Online Breathing Techniques: https://www.aleenakanner.com/– Follow Aleena on Instagram: https://www.instagram.com/aleenakanner/Upgrade Your Wellness– The Biological Blueprint Program: https://www.beautifullybroken.world/biological-blueprint– Beam Minerals: http://beamminerals.com/beautifullybroken — Code: BEAUTIFULLYBROKEN– Silver Biotics: bit.ly/3JnxyDD — 30% off with Code: BEAUTIFULLYBROKEN– LightPathLED: https://lightpathled.pxf.io/c/3438432/2059835/25794 — Code: beautifullybroken CONNECT WITH FREDDIEWork with Me: https://www.beautifullybroken.world/biological-blueprintWebsite and Store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/beautifullybroken.world/) YouTube: (https://www.youtube.com/@freddiekimmel Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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