Podcasts about T4

Why do so many people continue to struggle with thyroid symptoms, hormone imbalances, fatigue, weight gain, digestive issues, and poor health even when their lab work looks "normal"? In this episode of The Thyroid Answers Podcast, Dr. Eric Balcavage sits down with board-certified endocrinologist Dr. Cassie Smith to discuss her new book, Fix Your Gut, Fix Your Hormones, and the critical role gut physiology plays in hormone health. Dr. Smith shares her journey from traditional endocrinology to a more physiology-based approach after recognizing that many of her patients continued to get sicker despite receiving standard medical treatment. Together, they explore how gut health, chronic stress, inflammation, lifestyle factors, and cellular physiology influence hormone production, hormone metabolism, thyroid function, insulin regulation, estrogen balance, and overall health. The conversation highlights why optimizing lab values alone often fails to resolve symptoms and why addressing the underlying physiologic patterns affecting the body may be a more effective path toward lasting health improvements. In This Episode, You'll Learn: Why many patients continue to struggle despite "normal" lab results How gut health influences thyroid hormone conversion and utilization The connection between chronic stress, gut dysfunction, and hormone imbalance Why insulin resistance is often driven by more than just diet The role of the gut microbiome in estrogen metabolism and detoxification How inflammation can affect hormone signaling at the cellular level Why hormone replacement does not always resolve symptoms The importance of addressing lifestyle, sleep, stress, nutrition, and gut function alongside hormone optimization How chronic physiologic strain may contribute to ongoing thyroid and hormone symptoms Why understanding physiology may be more important than chasing lab numbers Key Topics Discussed Gut microbiome and hormone metabolism Thyroid physiology and T4 to T3 conversion Insulin resistance and metabolic dysfunction GLP-1 physiology Estrogen metabolism and the estrobolome Chronic stress and allostatic load Inflammation and cellular hormone signaling Leaky gut and immune activation Functional medicine and root-cause approaches Hormone replacement therapy considerations Lifestyle factors that influence hormone health About Dr. Cassie Smith Dr. Cassie Smith, MD is a dual board-certified endocrinologist, Founder of Modern Endocrine, and Chief Medical Officer of Renthyroid. She also serves on the medical faculty of Evexias Medical, a bioidentical hormone company. Dr. Smith is known for helping patients uncover why they still feel unwell despite "normal" lab results by using a holistic, root-cause approach to gut, metabolic, thyroid, and hormonal health. After completing her fellowship at the Harold Hamm Diabetes Center and being named a Top Doctor by 405 Magazine, Dr. Smith grew frustrated with the limitations of conventional care and built a model focused on treating the whole person—not just symptoms. She is the author of Fix Your Gut, Fix Your Hormones: The Critical Connection Your Doctor Is Missing… and Why You Still Feel Bad Despite Normal Labs, and through her popular podcast, Hormones, Metabolism, and You, she translates complex endocrinology into practical, actionable guidance. Today, Dr. Smith and her team help thousands of patients each year get to the root cause of gut health issues, hormone imbalances, thyroid disease, and weight resistance. She is licensed to provide telehealth and in-clinic care across 47 states, based in Oklahoma. She is the author of Fix Your Gut, Fix Your Hormones and host of the Hormones, Metabolism, and You podcast. Resources & Links

Calum Raistrick, Niall Darwin (onepunchnaz)APR Health Solutions Peptides: www.aprhealthsolutions.com - code nyleOptimize HRT Clinic: https://members.optimize-hp.com - code nyleMerch: https://www.aykons.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'nyle' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘nyle' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comRP Hypertrophy Training App: rpstrength.com/nyle (code nyle)0:00:00 - Intro0:02:04 - University Days & Naive PED Use0:05:03 - Gut Health & The 1.5g Protein Limit0:10:05 - Midsection Vacuum & Classic Weight Caps0:16:24 - The Real Cause of Waist Growth0:19:34 - Total Drug Load vs. Visceral Fat0:22:30 - Conditioning Secrets: Classic vs. Open0:28:28 - Niall's 12-Week Pittsburgh Prep Plan0:32:47 - Compound Tapering & Injection Risks0:35:02 - Extreme Prep Protocols: Martin & Boss0:40:57 - Systemic Stress & "Landing the Plane"0:43:12 - Blowing a Load the Night Before Show0:43:34 - John Meadows' "Grainy Skin" Secrets0:45:45 - Linear Peaking vs. Volatile Refeed Gauging0:48:45 - Strategic Atrophy & Leg Volume Slashes0:50:15 - Quad & Glute Volume Tiers0:52:08 - Tyler Smith's Extreme Leg Volume Slash0:53:19 - Peptide Protocols & Organ Protection0:55:21 - The Elite Client Portfolio0:57:11 - Coaching Content Creator Brandon Harding1:00:03 - Influencer Stress & Off-Season Fat Fear1:01:37 - Off-Season Fat Anxiety1:02:06 - What Makes a Coach Most Anxious?1:04:16 - Bodybuilding Page Tags & Lineups1:05:00 - Analyzing Kyron Holden & Ryan Terry1:06:47 - Managing Cortisol, Stimulants & Sleep1:11:46 - Advanced Peptides: SLU-332 & GC-11:12:44 - T3 Abuse vs. T4 & Sobetirome Replacement1:13:33 - GLP-1 Downsides in Contest Prep1:14:25 - Tirzepatide for Post-Show Reverse Phases1:16:05 - Why GLP-1s Ruin Peak Week1:20:36 - Compounding vs. Research Chemicals1:21:21 - Blood Panels & Wellness Specialists1:23:16 - GH & Insulin in Classic Physique1:24:46 - Insulin Dosing as an Off-Season Support1:25:24 - Nighttime GH Bolus vs. Microdosing1:27:00 - Patrick Tuor's Insulin-GH Synergy Theories1:28:55 - Lantus vs. Rapid-Acting Insulin Placement1:30:40 - Working with Niall Darwen1:31:29 - Height Measurements and Weight Caps1:32:44 - Height Manipulation & Spinal Decompression1:35:03 - Niall's Future Back Density Strategy1:36:26 - Pittsburgh Pro Post-Weigh-In Load1:37:37 - Off-Season Fiber & Gut Linings1:39:19 - Oral Steroid Toxicity & Digestion Dampening1:40:41 - Low-Dose Oral Strategies1:42:06 - 100mg Winstrol Motility Shutdown1:46:09 - Post-Show Recovery Phase vs. Rebound1:48:09 - Systemic Muscle Memory & Cell Sensitivity1:49:05 - Scientific Training Philosophy1:50:53 - Zachariah's 34kg Hypertrophy Miracle1:52:24 - Slow Eccentrics & Mind-Muscle Intent1:54:40 - Hyper-Focus During Sets1:56:53 - Comprehensive Blood Work Markers1:57:58 - Cruising Protocol Adjustments2:00:15 - Dietary Fats with Pre-Workout Insulin2:01:32 - Coaching Dynamics of Close Friends2:05:00 - Eric's Open Division Transition2:06:10 - Regional Coaching: UK Intensity vs. US Volume2:06:36 - Laszlo Karoly's Density & US Shows Strategy2:07:29 - Slow-Twitch vs. Fast-Twitch Muscle Genetics2:12:01 - Building Exceptional Muscle Mass2:14:20 - One Final Message: Back Yourself First

Fontes do episódio aqui:⁠https://portal.afya.com.br/podcasts/afya-news/05-06-2026Nesta sexta-feira, analisamos atualizações em endocrinologia reprodutiva, uma revolução na terapia celular oncológica e o papel dos jogos sérios no julgamento clínico. Abordamos as diretrizes atualizadas da American Thyroid Association, que estabelecem valores de referência por trimestre para TSH e T4, priorizando o rastreamento direcionado. Detalhamos os dados promissores da nova terapia CAR-T in vivo da Legend Biotech para linfoma não-Hodgkin, que gera as células de defesa diretamente dentro do corpo do paciente. Por fim, discutimos no Radar um estudo do JAMA que comprova como o jogo eletrônico Night Shift reduziu erros médicos e a subestimativa de traumas em idosos na emergência. Afya News. Informação médica confiável e atualizada no seu tempo.

Why Your Thyroid Is the "Check Engine Light" Your thyroid is the check engine light, not the engine. With Hashimoto's, the real story is happening in your gut, your immune system, and your stress physiology, often years before your thyroid shows it. If you have Hashimoto's and you're only chasing your thyroid numbers, you're missing the bigger question: why is your immune system attacking your thyroid in the first place? In this episode of the Medical Disruptor, I break down what Hashimoto's actually is, what the standard "replace the hormone" approach misses, and why your low-functioning thyroid is often a check engine light for something deeper, including gut health, gluten, infections, chronic stress, and toxins. I'm Dr. E, the NP with the PhD, and I help humans go from medically gaslit to medically empowered. We'll cover leaky gut and the gluten-to-TPO connection, the gut microbiome's role in converting T4 to T3, infections like EBV and H. pylori, how chronic stress and cortisol affect your thyroid, endocrine-disrupting toxins, and the smartest next steps to take before you reach for supplements. Want more practical health tips? Join my newsletter! https://freechapter.lpages.co/newsletter-opt-in/ Feeling "normal but not okay"? Grab my free guide to track your symptoms, spot your patterns, and get taken seriously https://freechapter.lpages.co/normal-but-not-okay-handout/ Check us out on social media: https://www.instagram.com/drefratlamandrehttps://www.facebook.com/drefratlamandrehttps://www.tiktok.com/@drefratlamandre #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters: 00:00 - Introduction 02:28 - Where Standard Treatment Falls Short 04:47 - The Gut, Gluten & Leaky Gut Connection 08:31 - Infections, Stress & Toxins 11:37 - What To Do Next: 5 Smart Steps 13:39 - Supplements That Actually Help Learn more about your ad choices. Visit megaphone.fm/adchoices

In today's podcast episode, I'm joined once again by thyroid expert and author Paul Robinson for a listener-led thyroid Q&A session. After our first thyroid conversation was so well received, I invited members from my Facebook community to submit their biggest thyroid-related questions, and we covered a wide range of topics surrounding hypothyroidism, Hashimoto's, T3 therapy, reverse T3, thyroid labs, symptoms, body temperature, hormone balance, and more. Some of the questions discussed in this episode include: • Is reverse T3 testing important? • How low is too low for TSH? • Why do some people with Hashimoto's struggle to convert T4 into T3? • What do high thyroglobulin and anti-thyroglobulin antibodies mean? • How can you support better T4 to T3 conversion? • Why do some people worsen on natural desiccated thyroid? • Can T3 dosing schedules change as healing occurs? • Can BHRT change thyroid medication needs? • Is there a connection between hypothyroidism, Hashimoto's, and migraines? • Can you still have hypothyroid symptoms with a “normal” body temperature? • What markers can help identify reverse T3 issues when testing is unavailable? • How can symptoms, pulse, blood pressure, and temperature help guide T3 dosing? This conversation is educational, nuanced, and filled with practical insights for those navigating thyroid symptoms and thyroid treatment. Paul Robinson is the author of: • The Thyroid Patient's Manual • Recovering with T3 • The CT3M Handbook Whether you are newly diagnosed, struggling despite “normal labs,” or wanting a deeper understanding of thyroid physiology and treatment approaches, I hope this conversation helps you feel more informed and empowered. Paul Robinson is a thyroid patient and thyroid patient advocate. Paul wrote 'The CT3M Handbook' as a companion book to 'Recovering with T3' to explain more about raising cortisol levels if needed. And Paul wrote his third book ‘The Thyroid Patient's Manual'. This book covers all types of thyroid medications (T4, T4/T3, NDT, and T3). His newest book "Articles on Hypothyroidism" combines the best of what Paul has discovered on his 35 year thyroid journey. Find out more about Paul here; https://paulrobinsonthyroid.com/ YouTube - @RecoveringwithT3 Instagram - / paulrobinsonthyroid Books; The Thyroid patients manual https://a.co/d/9VwgyLx The CT3M handbook https://a.co/d/iR5Zayv Recovering with T3 https://a.co/d/1035MD3

Many people with hypothyroidism or Hashimoto's are surprised when they begin experiencing symptoms like bloating, constipation, food sensitivities, gallstones, fat intolerance, reflux, or elevated cholesterol. These issues are often treated as separate conditions, but they may all be connected through one important physiological relationship: the connection between thyroid function, bile flow, gallbladder health, and digestion. In this episode, Dr. Eric Balcavage explains why thyroid physiology influences far more than metabolism. Thyroid hormone signaling affects stomach acid production, digestive enzymes, gut motility, bile production, gallbladder contraction, cholesterol metabolism, microbiome balance, nutrient absorption, and even the integrity of the gut barrier. When thyroid physiology is altered, digestive function often changes along with it. Dr. Balcavage explores the critical role bile plays in digestion and overall health, including how bile acids function as powerful signaling molecules that influence metabolism, inflammation, blood sugar regulation, thyroid hormone activation, microbiome health, and immune function. He also explains why reduced T4-to-T3 conversion can impair bile production, gallbladder emptying, and bile delivery into the small intestine, creating a cascade of digestive and metabolic symptoms. You'll learn why digestive symptoms, gallbladder problems, dysbiosis, leaky gut, and elevated cholesterol are often downstream effects of chronic stress physiology and reduced thyroid signaling rather than isolated problems. Dr. Balcavage also discusses common bile-support strategies including ox bile, TUDCA, phosphatidylcholine, taurine, glycine, choline, magnesium, and bitters, explaining when they may be helpful and why they often serve as temporary management tools rather than long-term solutions. Most importantly, this episode highlights why addressing the underlying causes of reduced thyroid signaling and chronic physiologic strain is essential for lasting recovery. In This Episode, You'll Learn: Why people with thyroid problems commonly develop gut, bile, and gallbladder issues The important role bile plays beyond fat digestion How bile acids influence metabolism, inflammation, microbiome balance, and thyroid hormone activation Why reduced T4-to-T3 conversion can impair bile production and bile flow The connection between hypothyroidism, elevated cholesterol, and gallbladder dysfunction How altered bile flow contributes to bloating, constipation, food sensitivities, dysbiosis, and leaky gut Why digestive symptoms are often adaptive responses to physiologic stress The relationship between chronic stress, reduced thyroid signaling, and digestive dysfunction When bile-support supplements like ox bile, TUDCA, taurine, glycine, choline, and phosphatidylcholine may be beneficial Why symptom management alone often fails to create long-term improvement The key factors that may be driving reduced thyroid signaling and digestive dysfunction beneath the surface Resources Mentioned:

Discover 7 key signs of a slow thyroid and learn how to distinguish between Hashimoto's and general hypothyroidism. Plus, discover natural ways to support thyroid health and address common thyroid problems naturally.

In this Her Stack series episode, I open up about maternal mental health, postpartum anxiety, and the invisible biological load mothers carry long after the six-week checkup is over. This episode is not just for the newly postpartum mother. It is for the mother whose kids are four, eight, fifteen, and still asking herself why she does not feel like herself. I share why motherhood structurally changes the brain, hormones, and nervous system, and why so many mothers are left feeling anxious, foggy, depleted, or unlike themselves without ever being properly screened or supported. I walk you through the science of the postpartum neurosteroid withdrawal, the gray matter changes that persist for years, and the five-system map underneath maternal brain fog. Then I break down the full four-pillar protocol I use with my one-to-one clients: foundational nutrition, lifestyle and biohacking tools, the supplement layer including some of the most under-discussed compounds for the maternal brain, and the advanced peptide layer including Semax, Selank, NAD+, and bioregulators. This is the episode every mother needs. Send it to one. Join The LongHer Life for women-specific guidance on peptides, hormones, and longevity. I TALK ABOUT:  02:00 - My free peptide masterclass for moms next week 04:10 — Why maternal mental health is not just a six-week postpartum issue 06:30 — The numbers every mother should know (and the screening gap that explains everything) 08:20 — How pregnancy structurally changes the brain (Nature Neuroscience, 2017) 11:40 — The neurosteroid withdrawal nobody warned you about, and the FDA's $34,000 drug that proves it is real 13:50 — Pillar 1: DHA, protein, ferritin, blood sugar stability, and methylated Bs for the maternal brain 22:40 — Pillar 2: Protected sleep cycles, morning sunlight, vagal nerve activation, and red light to the brain 28:00 — Yoga nidra and NSDR as the workaround for mothers who cannot engineer a protected sleep cycle 32:45 — Simplifying routines, meals, outfits, and planning to reduce mental load 35:00 — Co-regulation: Why one hour of real adult conversation is medicine 38:40 — Creatine for maternal mental health, depression support, and cognitive fatigue in sleep-deprived moms 40:50 — Saffron and inositol for postpartum mood, anxiety, racing thoughts, and the "can't shut off the brain" symptoms 42:15 — Magnesium L-threonate, glycine, vitamin D, and low-dose methylene blue for sleep, brain fog, mitochondrial support, and nervous system balance 45:25 — Why peptides are an advanced layer and should come after nutrition, lifestyle, and supplement foundations 46:10 — Semax and Selank for anxiety, cortisol support, BDNF, dopamine, brain fog, memory, and maternal brain support 50:00 — NAD+ and bioregulators (Cortagen, Cerluten, Epithalon) for maternal energy, neuronal support, circadian rhythm, melatonin, sleep, and long-term brain health 58:15 — Why postpartum anxiety and depression need different kinds of support, and why SSRIs work for some mothers and not others 1:00:00 — Why lingering symptoms matter and which labs mothers should check RESOURCES: Labs to ask your provider for: TSH, free T3, free T4, reverse T3, ferritin, vitamin D, DHA panel Join The LongHer Life for women-specific guidance on peptides, hormones, and longevity. Free Peptide Masterclass for Moms: Join the waitlist for the next live class. The Her Stack Planner: The first peptide tracking journal built around female biology. Crisis support: 988 in the US, 988 in Canada PRODUCTS MENTIONED: Supplements DHA (omega-3) Creatine monohydrate Saffron (Crocus sativus extract) Inositol (myo + d-chiro blend) Glycine Magnesium L-threonate (BiOptimizers code: BIOHACKINGBRITTANY) Vitamin D Lion's mane mushroom Bacopa monnieri Methylated B vitamins (methylcobalamin, methylfolate, P5P) Methylene blue (low dose, pharmaceutical USP only) Peptides Semax Selank NAD+ options NOVOS code: BIOHACKINGBRITTANY Nuchido TIME+ code: BIOHACKINGBRITTANY Nasal spray (Synchronicity Health code: BIOHACKINGBRITTANY) Bioregulators Cortagen Cerluten Epithalon LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music

Dr. Corey Schuler, PhD(c), FNP, DC, CNS, and director of medical affairs at Allergy Research Group, details his paper “Energy Allocation Resilience and Endocrine Integration” in the International Journal of Molecular Sciences. He introduces the Energy Allocation System (EAS), which emphasizes how the body allocates energy—not just produces it—and links many symptoms to impaired bioenergetics and resilience. They discuss mitochondria as energy generators and cellular signaling hubs, the integrated stress response and endocrine coordination (HPA axis, thyroid, gonads), and mitohormesis/eustress (exercise, fasting, heat/cold, circadian “zeitgebers”). Schuler explains nuanced testing for fatigue (diurnal cortisol, CGM patterns, thyroid markers including T3/reverse T3) and a case of a perimenopausal woman where oral contraceptives and cortisol dysregulation affected glucose patterns. They cover mitochondrial support (removing obstacles like pollutants/antibiotics, triglycerides, carnitine, dietary fats, micronutrients) and pacing/sequencing lifestyle interventions.

Have you been told your thyroid is normal, but you are still gaining weight, losing hair, exhausted by 3 PM, and living in a fog? If you have done everything right, clean eating, consistent exercise, and supplements, and nothing is working, this episode may finally give you the answer you have been looking for. It is not you. It is your thyroid.In this episode, Dr. Shivani Gupta sits down with Dr. Amie Hornaman, functional medicine thyroid specialist, host of The Thyroid and Hormone Fixer Podcast, and author of the new book The Thyroid Fix. Dr. Hornaman spent years being dismissed by six different conventional doctors before a seventh finally diagnosed her with hypothyroidism. Even then, the standard T4-only prescription left her no better. Backed by decades of clinical experience and the science of T3 conversion, reverse T3, and the thyroid-adrenal-hormone triangle, she breaks down exactly why so many women are undertreated and what to do about it.Dr. Hornaman shares her own story of gaining 40 pounds while competing in figure competitions and eating nothing but chicken, broccoli, and asparagus, and how it led her into functional medicine and eventually to building one of the most trusted thyroid practices in the country. Dr. Shivani also shares her personal journey from subclinical hypothyroidism to Armour Thyroid to discovering that even natural NDT was not fully working for her body. If you are a woman over 35 navigating perimenopause, unexplained weight gain, brain fog, or fatigue, and your doctor keeps telling you that you are fine, this episode is for you.WHAT YOU'LL LEARNWhy a normal TSH does not mean your thyroid is optimized, and the 5 tests every woman actually needs to ask for, including reverse T3 and TPO antibodiesThe T4-to-T3 conversion problem: why Synthroid and levothyroxine fail many women, and why T4-only treatment keeps you stuck in a low-energy, weight-gain cycleWhy natural desiccated thyroid like Armour and NP Thyroid is not automatically the answer, and how 80 percent T4 in NDT can still push you into reverse T3 lockdown modeHow perimenopause hormones trigger thyroid dysfunction, and the adrenal-progesterone-estrogen-TBG cascade that most doctors are not addressingThe Ayurvedic and lifestyle foundation: why calming inflammation, supporting digestion, and reducing cortisol are non-negotiables before thyroid hormone replacement can workDr. Hornaman's FIX Method, including the supplement, nutrition, and hormone replacement framework that has helped thousands of women get their lives backRESOURCES MENTIONED:The Inflammation Code (book)Fusionary Formulas Supplements — use code CODE15 for 15% off your first order https://fusionaryformulas.com/?utm_source=Show+Notes&utm_medium=Show+notes+&utm_campaign=Podcast+promo&utm_id=The+Inflammation+Code+Podcast7-Day Inflammation Detox ChallengeWork with Dr. Shivani — Free Discovery Call

Consultório do Rádio Livre: Em alusão ao Dia Internacional da Tireoide, comemorado em 25 de maio, a jornalista Anne Barretto entrevista especialistas para tirar dúvidas dos ouvintes da Rádio Jornal sobre saúde da tireóide. Afinal, como identificar problemas na tireoide? A endocrinologista geral, pediatra e diretora da Sociedade Brasileira de Endocrinologia e Metabologia, Dra. Daniela Coelho explica sobre o papel da tireoide dentro do corpo na produção de dois importantes hormônios: T3 e T4. Já o também médico endocrinologista, Dr. Fábio Moura, explica que a tireoide não tem uma função específica, mas que atua em todos os órgãos do corpo e destaca o que a faz ficar desregulada, como o hipotireoidismo.

Are you exhausted, cold, foggy, gaining weight, or feeling “off” even though your thyroid labs look “normal”? In this episode of The Trim Healthy Podcast, Serene and Pearl welcome back special guest Dr. Amie Hornaman, also known as The Thyroid Fixer, to talk about her new book The Thyroid Fix and why so many women are struggling without getting real answers. Dr. Amie shares her own powerful story of being dismissed and misdiagnosed, explains the difference between “normal” and truly optimal thyroid labs, and unpacks why T4-only medications may not be enough for many women. Together, we talk about Hashimoto's, perimenopause, menopause, cortisol, testosterone, birth control, T2, and why thyroid health is deeply connected to energy, metabolism, mood, sleep, weight, and long-term wellness. This conversation is full of straight talk, hope, and practical insight for women who know something is wrong but have been told everything looks fine. In this episode, we discuss: * Why “normal” thyroid labs may still leave women feeling terrible * Dr. Amie's personal journey with thyroid misdiagnosis * The connection between thyroid, sex hormones, cortisol, and metabolism * Why T4-only thyroid medication may not optimize thyroid health * Hashimoto's, autoimmune risk, and low testosterone * How perimenopause and menopause can impact thyroid function * Birth control's effect on thyroid and hormone health * What T2 is and why it may support metabolism and energy * Why thyroid hormone replacement is not “just another medication” Learn more from Dr. Amie at dramie.com Order The Thyroid Fix at thyroidfixbook.com Learn more about your ad choices. Visit megaphone.fm/adchoices

On today's episode, Elle Russ speaks with Karen about her harrowing thyroid journey. Her story is one of the most extreme and inspiring thyroid recoveries. After years of debilitating hypothyroid symptoms, failed T4-only treatment, crushing fatigue, hair loss, depression, migraines, and being repeatedly dismissed by doctors, Karen's health deteriorated so severely that she was told she could die if things didn't change quickly. Desperate for answers, Karen took her health into her own hands and discovered something most doctors never discuss: some thyroid patients simply do not do well on T4-only medication and may require direct T3 therapy - sometimes in much higher doses than conventional medicine is comfortable with. In this episode, Karen shares her brutal journey through sourcing medication internationally out of desperation, and finally finding the treatment that gave her life back. Today, after transitioning to T3-only therapy, Karen has: all-day stamina dramatically improved mental clarity freedom from constant migraines renewed confidence improved hair growth the ability to travel, hike, plan life again, and fully show up for her marriage and future This is a powerful conversation about perseverance, patient advocacy, medical gaslighting, and the life-changing impact of proper thyroid treatment. If you've ever been told your labs are "normal" while feeling anything but normal…this episode is for you. Learn more about how Elle can help you with your thyroid issues HERE.

Your Free T3 Is in Range — and That's the Problem Women are diagnosed with thyroid conditions at far higher rates than men — but what if the real thyroid crisis isn't being diagnosed at all? In this episode, Dr. Terri breaks down the overlooked, under-tested, and misunderstood reasons why women's thyroid systems fail, and why the standard lab panel almost every clinician runs is only telling half the story. From the gut's central role in hormone conversion, to the three minerals most women are chronically deficient in, to the enzyme that stress quietly dismantles — Dr. Terri maps out a comprehensive picture of thyroid dysfunction that goes far beyond what most patients hear at a routine checkup. If you've ever been told "your thyroid is normal" but you're still cold, fatigued, foggy, or stuck — this episode was made for you. This episode is for women who've been dismissed with a normal TSH, anyone on Synthroid or levothyroxine who's still symptomatic, and clinicians ready to expand their thyroid testing approach. What you'll discover: Why women are more vulnerable to thyroid conversion failure — and how hormones, gut health, and chronic stress all play a compounding role [6:21] The ferritin threshold that makes or breaks T4-to-T3 conversion — and what to do if you fall in the "gray zone" [9:24] How selenium deficiency can cause thyroid cells to literally burst from the inside out — and the direct link to Hashimoto's most doctors miss [15:39] The full comprehensive thyroid panel you should be asking for: TSH, free T4, free T3, and TPO antibodies [21:31] Why a free T3 "within range" is not the same as optimal — and what the bell curve data actually reveals about all-cause mortality risk [22:47] The deiodase enzyme most clinicians never discuss — and why synthetic T4 medications may be making conversion even harder [27:34] If your thyroid labs come back "normal" but you're still symptomatic, the problem isn't you — it's the range. -- The Dr. Terri Show is presented by EVEXIAS Health Solutions. For more, visit: https://www.evexias.com Connect with Dr. Terri:

This episode is all about lenses, including cine primes, new anamorphic options, and some crazy cine superzooms. Plus, we acquired a new set of lenses of our own. If you enjoy the show, we'd welcome your support on Patreon. It's only $3 per month and helps us keep the show running. You can check it out here: https://www.patreon.com/cameragearpodcast If you prefer to make a one-time donation, you can find us on Buy Me a Coffee: https://buymeacoffee.com/cameragearpodcast  Want to send us a question or comment, or just learn more about the show? Check out our website at https://cameragearpodcast.com, or email us directly at cameragearpodcast@gmail.com. Also, some of the product links in the notes below are affiliate links, which earn us a commission if you make a purchase at no additional cost to you. Notes: I'm Back Proposes a New Shutter Button as Its APS-C Kickstarter Closes-in on $1M [PetaPixel] Fuji XF 70-300 f/4-5.6 R LM OIS WR Lens Sirui IronStar Anamorphic Lenses Sirui Vision Prime T1.4 Cine Lenses NiSi Athena Cine Primes NiSi Jetmag Pro Magnetic Filters NiSi Athena Tuned Primes Viltrox Luna 30-300mm T4.0 Cine Lens Canon Cine-Servo 40-1200mm T5.0-T10.8 Lens

In this episode, Dr. Abby breaks down the gap between traditional thyroid screening and functional thyroid screening. Learn why checking just TSH if not the best approach, the reality behind common thyroid conditions, and the exact nutrients your body needs to thrive.Key Takeaways & Clinical Pearls1. The Essential 5-Part Thyroid Lab PanelChecking only TSH doesn't show the full picture. Dr. Abby recommends requesting these five:TSH: The brain's signal to the thyroid.Free T4: Your inactive storage hormone (cash in the bank).Free T3: Your active metabolic hormone (cash in your pocket).Reverse T3: The body's emergency brake, triggered by high stress or gut issues.Thyroid Antibodies (TPO & TgAb): Markers showing if the immune system is attacking your thyroid.2. Thyroid Conditions ExplainedHypothyroidism: Underactive thyroid function causing low energy, constipation, and a sluggish metabolism.Hyperthyroidism: Overactive thyroid function causing anxiety, a racing heart, and heat intolerance.Hashimoto's: An autoimmune condition that targets the thyroid. Because it is heavily tied to gut health and systemic inflammation, you cannot fully heal it without addressing the gut-immune connection.3. Nutrients to Build & Convert HormonesSelenium: The ultimate converter. Eating 2 Brazil nuts a day provides a clinical dose to help convert T4 into active T3 and calm antibody flares.Zinc: Crucial for TSH production and tissue absorption (always balance with copper).Tyrosine & Iodine: The physical building blocks of thyroid hormone, best sourced from clean fish and sea vegetables.Adrenals / Nervous System: Chronic stress stops active T3 conversion, making stress management foundational for thyroid healing.Connect with Dr. AbbyDr. Abby is accepting new functional health patients for extensive lab reviews, hormone mapping, and lifestyle consulting at Thrive Medical WNY (available in-person and virtually).Practice: Thrive Medical WNYBooking Link: Booking Link Here]Instagram: @dr.abbyborkowski

If you've been told your labs are normal but nothing feels normal - this episode is for you. Dr. Tabatha sits down with Dr. Amie Hornaman, the Thyroid Fixer, to unpack what your labs are missing, why T2 is the forgotten hormone, and what to do about it. Why 'normal' labs do not mean a healthy thyroid.The full thyroid picture: T1, T2, T3, T4 - and why most doctors only test twoT2: the forgotten thyroid hormone and how it supports metabolism without disrupting your natural productionHashimoto's, molecular mimicry, and why gluten removal is not optional for autoimmune thyroid diseaseThe gut-thyroid connection: why healing your gut is required for proper T4-to-T3 conversionThe link between under-optimized thyroid and insulin resistance, heart disease, and Alzheimer'sHow to advocate for yourself and ask for the right labsGet Dr. Amie's book The Thyroid Fix: thyroidfixbook.comSupport your thyroid with Thyro-Lift: shop.fasttofaith.com - use code PODCAST for 20% offScripture: Isaiah 40:29FREE 3-DAY LIVE MASTERCLASS - From Stuck to FreeJoin Dr. Tabatha May 26-28 for three live sessions designed for the woman who has done everything right and still doesn't feel well.Day 1 - Your Body Has Been Waiting Day 2 - Turn Your Healing Into Your Calling Day 3 - Why You're Still Not WellLive at 12PM EST. Same Zoom link all three days. Free to attend. Replay available for registered attendees.Register here: masterclass.fasttofaith.com/fromstucktofree

Hey Rockstars! I have another guest with me on the podcast, Connie Nightingale! Connie is a functional health and performance coach specializing in lab interpretation, hormone balance, and total body optimization. Her approach bridges fitness, nutrition, and root-cause health, helping clients go beyond “normal” labs to truly feel their best.Some topics from today's episode include:⭐️Connie's background as a functional health and performance coach specializing in lab interpretation and hormone balance⭐️How lab ranges are based on population data and may not reflect individual health⭐️The significance of testing timing (female hormones and menstrual cycle phases) for accurate interpretation⭐️The value of monitoring trends over time for better health insights and how to spot hidden health issues using lab trends before symptoms appear⭐️The impact of lifestyle on hormone health, especially during menopause and perimenopause⭐️The dangers of overprescribed hormones and the importance of personalized HRT protocols⭐️Starting with lifestyle modifications before medication adjustments⭐️The importance of taking active participation in health—tracking, questioning providers, and understanding lab data⭐️The potential to reverse or improve health conditions through informed actions and lab insights⭐️Key panels: CBC, CMP, lipid profile, thyroid (including TSH, free T3, free T4, antibodies), sex hormones (estrogen, progesterone, FSH, LH)Join the Kickstart Round 14! Kickstart is a guided group coaching experience designed for busy, high-achieving women over 40 who are done with yo-yo dieting and ready to implement proven, sustainable methods for fat loss and strength—tailored to their individual bodies and lifestyles. https://www.rockthatfitness.com/kickstartIf you have a chance, please rate and review the podcast so more women just like you can learn more about the Rockstar way! I appreciate you for your support and love ❤️Connie's Links:Website: https://www.connienightingale.com/Instagram: https://www.instagram.com/conniebegonnie/YouTube: https://www.youtube.com/channel/UC7duTyr-etc9gaobjJC19TAFacebook: https://www.facebook.com/conniebegonnieRock That Fitness Links:⭐️Link to join Rock That Fitness Membership Today https://www.rockthatfitness.com/rock-that-fitness-membership⭐️Join the Rockstar Fit Chicks Weekly Newsletter  https://rockthatfitness.kit.com/e10d0c66eb⭐️Check Out Our Exclusive Offer for Extensive Lab Work with Marek Health ⁠https://www.rockthatfitness.com/rock-that-fitness-marek-health⭐️Head to the Rock That Fitness Instagram Page https://www.instagram.com/rockthatfitness/ ⭐️Music from Uppbeat (free for Creators!):https://uppbeat.io/t/cruen/we-got-thisLicense code: RBWENWHGXSWXAEUE

If you have ever been told your thyroid is "normal" while you are exhausted, gaining weight, losing hair, constipated, freezing cold, and barely making it through the day, this episode is going to hit a nerve. Because the truth is, thyroid care is still failing women in a big way. Too many doctors are only testing TSH, stopping there, and missing the full picture completely. In this episode, I sit down with my friend Dr. Amie Hornaman to talk about why thyroid treatment is still so broken, especially for women in midlife. We go into one of the most important parts of this whole conversation: advocacy. Because when it comes to thyroid health, no one is coming to save you. You have to know what to ask for, what to test, what patterns to look for, and how to push for better care. If you have been dismissed, under-treated, or told your labs are fine while your body is clearly telling a different story, this episode will give you language, clarity, and a much better understanding of what may actually be going on. In this episode, we cover: Why thyroid care has not improved nearly enough for women Why testing only TSH is not enough The thyroid labs women need to ask for What free T3, free T4, reverse T3, TPO, and Tg antibodies actually tell you Why T4-only thyroid medication often does not work well How reverse T3 can put the brakes on your metabolism Why thyroid dysfunction can affect blood sugar, insulin, fertility, and sex hormones The connection between perimenopause, menopause, and new thyroid issues Why many women are being under-medicated for hypothyroidism How to advocate for yourself and find a practitioner who actually understands thyroid care Who this episode is for This episode is for women who suspect they have a thyroid issue, have already been diagnosed with hypothyroidism or Hashimoto's, or have been told their thyroid is "fine" even though they feel anything but fine. It is especially helpful for women in perimenopause and menopause who are dealing with fatigue, weight gain, brain fog, low mood, constipation, hair loss, or feeling like their body has suddenly stopped working the way it used to.   Dr. Amie Hornaman Grab a copy of Dr. Amies NEW BOOK: The Thyroid Fix: The No-Nonsense Guide to Fix Fatigue, Fogginess, and Fat That Won't Budge on Amazon     Sponsors Try Mito Q Hormone and metabolic control mitoq.com/karenmartel Code: MARTEL10 Get 30% off BATCH Gummies. Go to hellobatch.com/HORMONE and use code HORMONE at checkout. Get 15% off Masszymes By BiOptimzers products at bioptimizers.com/hormone with coupon code HORMONE.     Are you in perimenopause or postmenopause and struggling with symptoms—but not getting the support you deserve? At Midlife Solutions, we specialize in hormone optimization for women in midlife. Our all-female clinical team offers telehealth care across all 50 U.S. states, with the ability to prescribe bioidentical estrogen, progesterone, testosterone, and thyroid medication.   Book your FREE Hormone Discovery Call Find out what's really driving your symptoms and what your next best steps are.   Visit the website: https://karenmartel.com   Shop the Midlife Solutions Store Over-the-counter bioidentical hormone creams and oils — no prescription needed. Including: • Progesterone • Estrogen Face Cream • Vaginal Moisturizer and more!   Take the Hormone Quiz Discover hidden hormone imbalances that could be driving your symptoms. Get personalized results (and yes, they may surprise you).   Women's Peptide Weight Loss Program Clinically guided, hormone-aware weight loss for midlife women.   Midlife RESET HRT Program A complete, supportive approach to hormone replacement therapy in midlife.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

Diagnosis, workup, and the four-step treatment protocol for thyroid storm. Hosts: Annaliese Elam, MD Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Thyroid_Storm.mp3 Download Leave a Comment Tags: Critica Care, Endocrine, Thyroid Storm Show Notes I. Pathophysiology & Diagnosis Definition: Life-threatening hypermetabolic state resulting from decompensated thyrotoxicosis. Hormonal Profile: Absolute levels of total T₄/T₃ often mirror uncomplicated thyrotoxicosis; storm is driven by rapid rate of rise, increased catecholamine sensitivity, or increased free T₄/T₃ concentrations. Clinical Presentation: Hyperpyrexia (e.g., 104.2°F) Tachycardia/Arrhythmias (e.g., 155 bpm) Altered Mentation: Agitation, delirium, or psychosis; often the primary differentiator between “storm” and “compensated” hyperthyroidism Warm, moist skin Precipitating Events: Infection, trauma, or surgery Parturition Abrupt cessation of antithyroid medications Burch-Wartofsky Point Scale (BWPS): ≥ 45: Highly suggestive of Thyroid Storm 25–44: Suggestive of impending storm < 25: Storm unlikely Note: High sensitivity but low specificity; can be skewed by unrelated febrile illness. II. Laboratory & Ancillary Findings Thyroid Panel: Characteristically low TSH with elevated free T₄ and T₃. Metabolic Abnormalities: Mild hyperglycemia (catecholamine-induced insulin inhibition) Mild hypercalcemia Elevated LFTs and leukocytosis Cardiovascular: EKG may show sinus tachycardia or atrial fibrillation with rapid ventricular response. III. Management: The Four-Step Blocking Strategy Step 1: Sympathetic Blockade (Beta Blockers) Agent of Choice: Propranolol Mechanism: Non-selective blockade; in high doses, inhibits peripheral conversion of T₄ to T₃. Dosing: PO: 60–80 mg every 4–6 hours IV: 0.5–1 mg over 10 minutes Critical Pitfall: Avoid in patients with acute decompensated heart failure with systolic dysfunction; risk of cardiovascular collapse. Step 2: Inhibition of Hormone Synthesis (Thionamides) Agent of Choice: Propylthiouracil (PTU) preferred over Methimazole in life-threatening storm. Mechanism: Blocks synthesis of new hormone and inhibits peripheral T₄-to-T₃ conversion (decreases T₃ by ~45% in 24 hours). Dosing: 200–250 mg PO every 4 hours Step 3: Inhibition of Hormone Release (Iodine) Agents: Potassium iodide (SSKI) or Lugol’s solution Critical Timing: Must wait at least 60 minutes AFTER thionamide administration. Rationale: Immediate iodine administration provides substrate for new hormone synthesis (Wolff-Chaikoff effect bypass), potentially worsening thyrotoxicosis. Step 4: Inhibition of Peripheral Conversion & Adrenal Support Agent: Glucocorticoids (Hydrocortisone) Mechanism: Inhibits peripheral T₄ to T₃ conversion and treats potential relative adrenal insufficiency. Dosing: 300 mg IV loading dose, followed by 100 mg IV every 8 hours IV. Supportive Care & Avoidance Measures Hyperpyrexia Management: Acetaminophen is the standard of care Avoid Aspirin: Salicylates displace thyroid hormone from thyroid-binding globulin (TBG), increasing free T₄/T₃ levels Volume Resuscitation: Aggressive IV fluids; patients are often profoundly dehydrated May require 3–5 liters of isotonic crystalloid per 24 hours Take Home Points I. Diagnostic Essentials Clinical Diagnosis: Based on hyperpyrexia, cardiovascular dysfunction, and altered mentation. Key Differentiator: Altered mentation (agitation, delirium, psychosis) is often the sole finding distinguishing “storm” from “compensated” thyrotoxicosis. Burch-Wartofsky Point Scale (BWPS): ≥ 45: Highly suggestive of storm. 25–44: Suggests impending storm. < 25: Storm unlikely. Note: High sensitivity, low specificity (e.g., hyperthyroid + flu can score > 45). Triggers: Infection, trauma, parturition, or abrupt cessation of antithyroid drugs. II. The Four-Step Blocking Strategy Beta Blockade (Propranolol): Dose: 60–80 mg PO q4–6h or 0.5–1 mg IV over 10 min. Action: Blocks symptoms and inhibits peripheral T4 to T3 conversion. Caution: Avoid in acute decompensated heart failure with systolic dysfunction. Thionamides (PTU): Dose: 200 to 250 mg every four hours. (note: some resources suggest a loading dose beforehand) Action: Preferred over methimazole; blocks new hormone synthesis and peripheral T4 to T3 conversion. Iodine (SSKI/Lugol’s): Timing: Must wait ≥ 60 minutes AFTER thionamide dose. Action: Blocks hormone release. Pitfall: Early iodine provides substrate for new hormone synthesis, worsening the condition. Glucocorticoids (Hydrocortisone): Dose: 300 mg IV load, then 100 mg IV q8h. Action: Blocks conversion and provides adrenal support. III. Critical Supportive Care Hyperpyrexia: Use Acetaminophen. NEVER Use Aspirin: Displaces thyroid hormone from binding proteins, acutely increasing free T4/T3 levels. Volume: Aggressive fluid resuscitation; patients may require 3–5 L/day due to profound dehydration. Read More

Andrea Donsky is a registered holistic nutritionist with 20+ years of experience, a published menopause researcher, the co- founder of Morphus, the host of this podcast, Menopause Reimagined, and the author of Nourishing Menopause (Simon & Schuster) and Unjunk Your Junk Food.In this episode, Andrea sits down with Dr. Amie Hornaman, "The Thyroid Fixer," to unpack what happens to your thyroid in perimenopause and menopause. If you've been told your labs are "normal," but you still feel exhausted, foggy, freezing cold, and like your body isn't your own, this conversation is for you. Dr. Amie introduces a term every woman over 40 should know: thyropause.What you'll learn:Why so many perimenopause symptoms are actually undiagnosed thyroid issuesWhat thyropause is and why Hashimoto's often switches on after 40The five thyroid labs to ask your doctor for (and what to do if they refuse)Why T4-only medications like Synthroid may not be enough on their ownHow to find a provider who actually understands thyroid hormone replacementChapters:0:00   Why your thyroid tanks after 40 (thyropause explained)2:00   Welcome back to Menopause Reimagined & meet Dr. Amie Hornaman5:10   What the thyroid actually does (from hair loss to heart rate)8:45   Hypothyroidism vs hyperthyroidism: which one hits women hardest12:00  Thyropause: the perimenopause and Hashimoto's connection16:15  1 in 8 women? Why the real number is closer to 1 in 419:25  Medically gaslit: Andrea's story of being dismissed by her doctor23:40  The thyroid tests your doctor probably isn't ordering (TSH, free T3, reverse T3, TPO, TG)28:30  T3 vs T4: why Synthroid alone may not be enough33:45  Why you can stay on thyroid medication for life (and why that's okay)38:10  Finding the right dose: the trial-and-error reality42:25  Inside The Thyroid Fix book and Fixer Formulas supplements47:00  Where to find Dr. Amie and grab the bookLinks:The Thyroid Fix: The No-Nonsense Guide to Fix Fatigue, Fogginess, and Fat That Won't Budge https://amzn.to/3PrfxvrLearn more about Dr. Amie Hornaman here: https://dramie.com/Send us Fan Mail ======Morphus: Menopause Reimagined

In this episode of Hope Natural Health, Dr. Erin Ellis talked about the common and frustrating disconnect between "normal" thyroid lab results and the very real symptoms of thyroid dysfunction that many women experience. She dives deep into why the standard TSH screening often misses the full clinical picture and explores the hidden gaps in conventional thyroid testing.   In this episode, you will learn: Why TSH is a brain signal not a thyroid hormone and why a "normal" result doesn't mean your thyroid is functioning optimally. How the body struggles to turn T4 (storage) into Free T3 (active hormone) due to stress, gut issues, and nutrient deficiencies. How chronic stress can signal your body to actively block your thyroid receptors. The importance of testing TPO and TG antibodies to catch autoimmune activity that TSH screens completely overlook. Why "average" isn't the same as "optimal" and how tighter functional ranges can help identify the root cause of fatigue, brain fog, and weight stalls. How cortisol, estrogen, and gut health directly influence your thyroid performance.   Resources Mentioned: The "Why Am I So Tired?" Assessment: A 10-minute clinical framework to help identify your hormone patterns: https://whyamisotired.hopenaturalhealth.com/ Book a discovery call for a comprehensive testing and personalized plan: https://hopenaturalhealth.com/   For more on Dr. Erin: Join The Hope Circle Community: https://hormonehealingproject.drerinellis.com/communities/groups/the-hope-circle/home?invite=69120d498b7e3f60397656b8 Work with Dr. Erin here: https://p.bttr.to/3E88ps4 Buy Dr. Erin's Supplements here: https://drerinellis.com/shop Get the Period Productivity Planner here: https://www.amazon.com/dp/B0BBYBRT5Q?ref_=pe_3052080_397514860 Download the FREE Menstrual Cycle Nutrition Guide here: https://detox.drerinellis.com/ Watch The Free Video "7 Hormones Affecting Your Weight Loss Goals" here: https://weightloss.drerinellis.com/ Let's Be Friends: Follow Dr. Erin on Instagram: https://www.instagram.com/dr.erinellis/ Follow Dr. Erin on Facebook: https://www.facebook.com/drerinellisnmd Follow Dr. Erin on TikTok: https://www.tiktok.com/@dr.erinellis?lang=en Join the Free Hope Circle Community: https://hormonehealingproject.drerinellis.com/communities/groups/the-hope-circle/home?invite=69120d498b7e3f60397656b8 Bookmark Dr. Erin's Website: www.drerinellis.com Subscribe to Hope Natural Health on YouTube: https://www.youtube.com/channel/UChHYVmNEu5tKu91EATHhEiA Follow Hope Natural Health on FB: https://www.facebook.com/hopenaturalhealth Sign up for Newsletters here: https://booking.hopenaturalhealth.com/widget/form/VUubL7MNYELduwQL8ssI

Save your seat in the free Thyroid and Hormone class https://fixyourthyroid.com/natalie  If you are a woman in midlife who has been told everything is fine when you know in your body that something is NOT fine, this episode is going to change everything. I have Dr. Amie Hornaman, The Thyroid Fixer, back on the show, and we are going somewhere we have never gone before. One in eight women will develop a thyroid condition in her lifetime. Eighty-eight percent of us are metabolically unhealthy. And yet most doctors run ONE test, look at one number, tell us we are normal, and send us home with an antidepressant. Meanwhile we are gaining weight, losing our hair, can't sleep, can't think, can't lose a pound to save our lives, and being told it is just stress, just aging, just menopause. Today we are tearing that apart. Dr. Amie saw SEVEN doctors before she was finally diagnosed. She is now licensed to prescribe thyroid and bioidentical hormones in all 50 states and most of Canada. She built the Better Thyroid and Hormone Institute, hosts The Thyroid (and Hormone) Fixer Podcast, and has helped thousands of women globally finally get answers. We go DEEP on: Why the standard TSH-only test misses almost everyone, and the six tests you need to ask for by name THYROPAUSE: Dr. Amie's term for what happens when thyroid dysfunction collides with perimenopause and menopause (and why so many women are being treated for the wrong one) The T4-only medication trap: why Synthroid and levothyroxine fail an estimated 98% of patients Reverse T3, the silent saboteur that blocks your active thyroid hormone from getting into your cells Natural desiccated thyroid, the controversy, FDA scrutiny of animal-derived medications, and where Dr. Amie stands T2: the FORGOTTEN thyroid hormone with 30+ years of research that burns fat at the mitochondrial level, does not suppress your own thyroid, does not jack up your heart rate, does not require a prescription, and is showing up in studies as a potential anti-obesity treatment What Ozempic, Wegovy, and Mounjaro are actually doing to your thyroid (and why some women lose ZERO weight on GLP-1s no matter how high they push the dose) The estrogen, progesterone, testosterone, cortisol, and insulin connection: why you cannot fix the thyroid without addressing the whole hormonal system Antibody-support strategies: gluten elimination, black cumin seed oil, low-dose naltrexone, and thymosin alpha Iodine titration cautions, medical gaslighting, and what to say when your doctor refuses to run the full panel The Monday morning action plan: exactly what to do this week if you suspect your thyroid is the missing piece This is not a thyroid 101 episode. This is the conversation I wish every midlife woman was given the day her labs came back normal. You are not broken. You are not crazy. And you are not alone. Sign up for the free Thyroid and Hormone class https://fixyourthyroid.com/natalie    Connect with Dr. Amie: Podcast: The Thyroid (and Hormone) Fixer Instagram: @dramiehornaman Book: https://thyroidfixbook.com/ Live lab-review class https://fixyourthyroid.com/natalie  Better Thyroid and Hormone Institute: dramiehornaman.com   APPROXIMATE TIMESTAMPS: 00:00 — The medical gaslighting that is keeping midlife women sick 06:00 — The full thyroid panel: the six tests to ask for by name 12:00 — Introducing THYROPAUSE: where thyroid meets menopause 20:00 — How estrogen, progesterone, testosterone, and cortisol all impact your thyroid 28:00 — Why T4-only medication (Synthroid, levothyroxine) fails 98% of patients 34:00 — Natural desiccated thyroid, FDA scrutiny, and individualized dosing 40:00 — T2: the forgotten thyroid hormone that burns fat without touching your gland 48:00 — Who should consider T2 (and why it does not require a prescription) 52:00 — What Ozempic and the GLP-1s are actually doing to your thyroid 58:00 — How to protect your thyroid if you are currently on a GLP-1 62:00 — Lifestyle non-negotiables: morning sun, protein, resistance training, sleep, blood sugar 67:00 — Your Monday morning action plan if you suspect your thyroid is the missing piece   Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube   Learn More About Dr. Amie Hornaman  Instagram ➜ https://www.instagram.com/dramiehornaman Website ➜ https://fixyourthyroid.com/natalie      Thank you to our show sponsors:  MITOQ: Take control of healthy aging and longevity. Get 10% off using code NATALIEJILL at checkout on https://www.mitoq.com/  BIOPTIMIZERS: Get the digestive enzymes I take with every meal here https://www.bioptimizers.com/nataliejill Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com   Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit   For advertising inquiries: https://www.category3.ca/  Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen.  Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.

Today, I'm joined by the incredible Dr. Amie Hornaman, a leading thyroid expert and author of the brand new book, The Thyroid Fix. In our conversation, Dr. Hornaman opens up about her personal struggle with undiagnosed thyroid disease—a journey marked by frustrating medical gaslighting and the dismissive “you're normal” diagnoses from doctor after doctor. She reveals how that experience led her to become a passionate advocate for women (and men) suffering from thyroid dysfunction and a pioneer in holistic, root-cause approaches to healing. Episode Timestamps: Introduction and show purpose ... 00:00:00 Dr. Hornaman's personal story and medical gaslighting ... 00:05:05 Journey to functional medicine and importance of symptom-based care ... 00:11:00 Recognizing key thyroid-related symptoms ... 00:14:51 Wearables and tracking thyroid-related trends ... 00:17:18 Understanding thyropause and hormone fluctuations after 40 ... 00:19:31 Impact of thyroid function on overall longevity and health ... 00:23:43 T4-only medication debate and need for personalized treatment ... 00:36:19 Why T4-only persists in conventional practice ... 00:40:40 T2, metabolism, mitochondrial health, and iodine ... 00:45:21 GLP-1 medications, thyroid optimization, and weight loss stories ... 00:50:16 Personalization of thyroid numbers and treatment ... 00:53:46 Functional versus conventional thyroid lab ranges ... 00:54:59 Thyroid's connection to mood and mental health ... 00:56:42 When lifestyle alone can't restore thyroid health ... 00:58:39 Biggest myth: TSH and T4-only standard of care ... 01:07:59 Our Amazing Sponsors: O₃RACLE by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off. Quantum Upgrade - Supports nervous system balance without wearables or apps—just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it's easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT15 to start the free 15 day trial. MassZymes by BiOptimizers – A full-spectrum digestive enzyme formula with 4x more protease to help break down protein into usable amino acids so your body actually benefits from what you eat—try it risk-free with a 365-day money-back guarantee and save 15% at bioptimizers.com/bionat with code BIONAT. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

In this powerful episode, Dr. Fiona Lovely welcomes back her friend and colleague, Dr. Amie Hornaman—known globally as "The Thyroid Fixer." Dr. Amie is a functional medicine expert, host of the top-rated The Thyroid Fixer podcast, and author of the new book The Thyroid Fix: The No-Nonsense Guide to Reclaiming Your Health. Together, they pull back the curtain on why conventional medicine continues to fail women when it comes to thyroid and hormone health. Dr. Amie shares her journey of being misdiagnosed and how that fueled her mission to help women stop wishing on a rainbow for their health to improve. She explains why relying solely on TSH and T4 is a dangerous gamble, revealing that the real story lies in free T3 and reverse T3. Listeners will learn why T4-only medication like Synthroid often falls short and how to advocate for proper testing and treatment. The conversation also explores the forgotten thyroid hormone T2, its role in burning fat without losing muscle, and how GLP-1 medications intersect with thyroid function. Dr. Amie provides scripted, respectful language for women to use with their doctors, including a powerful "nuclear option" to ensure their concerns are documented. Episode Highlights: Why TSH is a misleading marker and which two tests truly matter for thyroid health. The problem with T4-only medication and why it can backfire. How to approach your doctor without overwhelming them—three bullet points, no life stories. The fascinating role of T2 in metabolism and weight loss. A candid discussion on thyroid nodules, unnecessary surgeries, and patient advocacy. Tune in to learn how to become the CEO of your own health, because waiting for your doctor to catch up is no longer an option.   Thank you to our sponsors for this episode: Women in perimenopause and menopause talk about wanting the same things — less bloating, no afternoon crash after eating, steady energy. MassZymes is perfect for helping your body's ability to actually process what you eat. MassZymes uses a full-spectrum blend of 18 enzymes. That means you're getting more out of the food you eat. Plus, it works across different stomach acid levels, which can really matter as we age. Here's what you get when you go to bioptimizers.com/lovely and use code LOVELY: 15% off your entire order AND a free bottle of Masszymes — BiOptimizers' best-selling digestive enzyme — added to your order automatically when you use our exclusive code.

If you're dealing with fatigue, brain fog, digestive issues, or stubborn symptoms that won't go away… you've probably been told it's your thyroid. So you test your labs. You adjust medication. You try to "optimize" your numbers. And yet… nothing really changes. In this episode of the Thyroid Answers Podcast, Dr. Eric Balcavage explains why many persistent "thyroid" symptoms are not actually driven by thyroid dysfunction but by immune activation and inflammation. You'll learn how your body shifts into a protective, stress-adaptive state under perceived threat, and how those changes directly impact thyroid physiology. What looks like a thyroid problem on paper is often a signal that your system is overwhelmed… not broken. Dr. Balcavage walks through why chasing lab values or suppressing symptoms can leave people stuck in what he calls "thyroid purgatory," and why real progress requires a different approach entirely. If you've been doing all the "right things" but still don't feel like yourself… this episode will help you understand why—and what to focus on instead. What You'll Learn: • Why many thyroid symptoms are driven by immune activation, not thyroid dysfunction • How inflammation and perceived stress change thyroid physiology • Why TSH, free T4, and free T3 don't tell the whole story • What "thyroid purgatory" is and why so many people get stuck there • How the immune system shifts metabolism under stress or threat • Common hidden stressors (infections, toxins, mold, poor sleep, under-eating, overtraining, chronic stress) • Why symptom suppression and lab manipulation often fall short • The connection between stress, metabolism, and hormone disruption • Why building capacity must come before trying to "fix" the system • How to start reducing load and supporting your body in a more effective way Learn More About Dr. Eric Balcavage Dr. Eric Balcavage is the co-author of The Thyroid Debacle and the creator of: • State-Based Medicine™ • The Adaptive Thyroid Model™ • The Strategic Thyroid Solution™ His work focuses on helping patients and practitioners understand thyroid physiology through the lens of metabolic stress, adaptation, and whole-body regulation. Connect With Dr. Eric Balcavage Website: https://www.drbalcavage.com Instagram: https://www.instagram.com/drericbalcavage Facebook: https://www.facebook.com/drericbalcavage YouTube: https://www.youtube.com/@drericbalcavage If you enjoyed this episode, be sure to subscribe, leave a review, and share it with someone who may be struggling with thyroid issues or chronic fatigue.

What if your “slow metabolism” isn't about calories at all… but a hidden thyroid problem nobody has caught yet? In this eye-opening episode of the Metabolic Freedom Podcast, Ben Azadi sits down with renowned thyroid expert Dr. Amie Hornaman to uncover the real connection between thyroid health, stubborn belly fat, fatigue, hormone dysfunction, and metabolic resistance. Dr. Amie explains why millions of people are being told their labs are “normal” while still struggling with weight gain, brain fog, constipation, hair loss, anxiety, and exhaustion. She reveals why standard thyroid testing often misses the real issue, how reverse T3 can completely shut down fat burning, and why many people feel worse even while taking thyroid medication. Ben and Dr. Amie also break down the dangerous myth of “eat less and exercise more,” the truth about fasting with hypothyroidism, why insulin resistance and thyroid dysfunction go hand in hand, and how hidden inflammation, stress, toxins, and gluten may be sabotaging your metabolism. If you've been doing everything “right” and still can't lose weight or feel good, this conversation may finally explain why.

In this episode, I sit down with Dr. Amie Hornaman, also known as the Thyroid Fixer, to unpack the real reasons so many people struggle with fatigue, weight gain, brain fog, and hormone imbalances without getting clear answers. We dive into her personal journey of being misdiagnosed multiple times, what finally led her to answers, and why so many patients today are still being overlooked in traditional medicine. Together, we discuss what is actually happening beneath the surface when it comes to thyroid function, including the critical difference between T4 and T3, the role of reverse T3, and why a one-size-fits-all approach to treatment often falls short. I also ask the questions so many of you are wondering like how to advocate for yourself with your doctor, what labs truly matter, and how to know if your current treatment is actually working.  Topics We Cover in This Episode:  Why “normal labs” might not mean optimal thyroid function The hidden reason some people never feel better on standard thyroid medication What your body may be doing instead of converting thyroid hormone properly The overlooked factors that could be sabotaging your energy and metabolism Why some people thrive on certain thyroid treatments while others don't How stress, gut health, and nutrients quietly influence your thyroid What most doctors were never taught about thyroid optimization The signs your body is trying to tell you something deeper is off Resources & Links Dr. Amie's Links Facebook: Amie Hornaman Nutrition and Functional Medicine YouTube: Dr. Amie Hornaman Instagram: @dramiehornaman Thyroid Optimization Guide: https://health.dramie.com/thyropause  7 Day Thyroid Healing Kickstarter: https://fixyourthyroid.com/7daykickstarter  Thyroid on Trial: https://health.dramie.com/thyroid-on-trial-optin 

In this episode of Keeping Abreast, Dr. Jenn Simmons sits down with thyroid and hormone specialist Dr. Amie Hornaman to dismantle the standard of care that is leaving millions of women dismissed, misdiagnosed, and under treated. They cover what the full thyroid panel actually looks like, why T4-only therapy fails the vast majority of patients, and how the thyroid is connected to every other hormone system in a woman's body.What happens when a competitive athlete starts gaining weight, losing hair, and can't get a single doctor to take her seriously? Dr. Amie found out in her 20s with 40 pounds of unexplained weight gain, six doctors, six dismissals, and one mentor who finally ran the right tests and changed the course of her life and career. If you've ever been told your thyroid is fine while your body is telling you otherwise, this is the episode you've been waiting for.What You'll LearnWhy testing TSH alone is not a thyroid workup and what the five markers are that actually tell the full storyWhat free T3, free T4, and reverse T3 mean and why reverse T3 is the most dismissed marker in the panelWhat thyroid antibodies TPO and TGA reveal about Hashimoto's and why your doctor's normal range is meaninglessWhy 95% of hypothyroid cases are Hashimoto's and why your antibodies may already be elevated even if your doctor says they are notWhy your GLP-1 will stop working if your thyroid is not optimized firstHow estrogen dominance low progesterone high cortisol insulin resistance and low ferritin all interfere with thyroid functionWhy your insurance-based doctor cannot give you proper thyroid care even if they want toWhat the FDA's move against natural desiccated thyroid is really about and who benefitsWhy testosterone is protective against breast cancer and why women are being denied access to itWhat it actually feels like when your thyroid is optimized and how Dr. Amie gets patients thereEpisode Timeline:00:00 Show Intro01:08 How Dr. Amie Became Dr. Jenn's North Star05:02 Pain to Purpose: 40 Pounds and Six Dismissals08:37 Where Conventional Medicine Gets It Wrong16:58 Why Thyroid Disease Is at Epidemic Levels19:14 The Full Thyroid Panel You Actually Need36:43 Why T4-Only Therapy Fails Almost Everyone40:27 The Hormonal Web Nobody Is Addressing45:32 What Thyroid Optimization Actually Looks Like52:22 The FDA Threat to Natural Desiccated Thyroid59:42 Dr. Jenn's Testosterone Gatekeeping Story01:05:22 The Importance of Prevention in HealthcareFind Dr. Amie Hornaman Website: dramie.com | Book: thyroidfixbook.comTo talk to a member of Dr. Jenn's team and learn more about working privately with Dr. Jenn visit: https://calendly.com/stephanie-1031/clarity-callTo get your copy of Dr. Jenn's book, The Smart Woman's Guide to Breast Cancer, visit: https://tinyurl.com/SmartWomansBreastCancerGuideTo purchase the auria breast cancer screening test go here https://auria.care/ and use the code DRJENN20 for 20% Off.Connect with Dr. Jenn:Website: https://www.jennsimmonsmd.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons

Today, I am thrilled to reconnect with my friend and colleague, Dr. Amie Hornaman, also known as the Thyroid Fixer. She is the founder and CEO of the Advanced Thyroid and Hormone Clinic, host of the Thyroid Fixer podcast, and a sought-after speaker and author. In today's conversation, we discuss her brand-new book, The Thyroid Fix, and explore the current thyroid-related silent epidemic. We dive into mitochondrial dysfunction, thyroid optimization, and the significance of reverse T3, also unpacking the symptoms that impact your digestion and hypothyroidism, environmental triggers, oral contraceptive use, and how it increases your susceptibility and risk for developing hypothyroidism. We also examine natural desiccated thyroid, the effects of iodine supplementation, and Dr. Hornaman shares her top three lifestyle strategies for a healthy thyroid. This is a truly insightful and helpful conversation, especially for those in my community who are struggling with an underactive thyroid- myself included. Stay tuned for more. IN THIS EPISODE, YOU WILL LEARN: How women with hypothyroidism are often misdiagnosed or medically gaslit Why Dr. Hornaman believes that the actual number of Americans with hypothyroidism may be far higher than current statistics suggest What reverse T3 is and why it increases when we are stressed How thyroid function impacts the way that cells produce energy How a low-functioning thyroid can slow digestion and cause constipation Why do some women require more personalized thyroid treatment than standard T4 therapy? How environmental toxins can disrupt thyroid health Why long-term oral contraceptive use could increase the risk of hypothyroidism Some simple lifestyle habits and biohacks to improve stress resilience in women with thyroid dysfunction Bio: Dr. Amie Hornaman Dr. Amie Hornaman, known as The Thyroid Fixer, is the founder of the Advanced Thyroid and Hormone Clinic and host of the top-rated podcast The Thyroid Fixer. She is the author of the thyroid bible, The Thyroid Fix, the last thyroid book you'll ever need to understand fatigue, fogginess, and stubborn weight. Driven by her own experience with misdiagnosis, Dr. Amie helps people optimize their thyroid, reclaim their health, and step fully into the badass humans they were meant to be. Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow  Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Amie Hornaman On her website Pre-order a copy of The Thyroid Fix  

Thyroid Symptoms, Normal Labs, and Root Causes: Dr. Kevin Smith on Hashimoto's, Functional Medicine, and Chronic Conditions | Conversations with a Chiropractor Episode Description In this episode of Conversations with a Chiropractor, Dr. Stephanie Wautier sits down with Dr. Kevin Smith, a functional medicine practitioner and founder of the Chronic Conditions Center in Pittsburgh, Pennsylvania. Dr. Smith specializes in helping people better understand the root causes behind chronic health problems, including thyroid dysfunction, gut issues, autoimmunity, chronic pain, inflammation, peripheral neuropathy, insulin resistance, and other complex conditions. This conversation focuses heavily on thyroid health, especially the frustration many people feel when they have symptoms of hypothyroidism, but are told their labs are "normal." Dr. Smith explains why thyroid symptoms can involve far more than a simple TSH reading, and why many cases of hypothyroidism may be connected to Hashimoto's disease, an autoimmune condition that affects the thyroid. Stephanie and Dr. Smith talk through common thyroid symptoms, including fatigue, hair loss, weak nails, digestive changes, sleep issues, brain fog, mood changes, infertility, and skin problems. They also discuss why a deeper look at the body may include the immune system, gut health, liver function, blood sugar, cortisol, sex hormones, inflammation, food sensitivities, unresolved infections, and nutrient status. The episode also explores the difference between managing symptoms and looking for the underlying reasons a person may not feel well. Dr. Smith shares how he uses detailed intake forms, comprehensive lab testing, metabolic questionnaires, food sensitivity testing, lifestyle changes, nutrition, supplements, and retesting to help patients better understand what is happening in their body. This conversation is educational and is not a replacement for personal medical care. If you are dealing with thyroid symptoms, autoimmune concerns, medication questions, or chronic health issues, work with a qualified healthcare provider who can evaluate your individual situation. In This Episode, Discover Common symptoms of hypothyroidism and low thyroid function Why "normal labs" may not tell the whole story The connection between Hashimoto's disease and thyroid dysfunction Why Dr. Smith describes many thyroid issues as immune system issues How the brain, pituitary gland, thyroid, liver, gut, and carrier proteins all play a role in thyroid function Why every cell in the body depends on thyroid hormone for energy regulation How chronic inflammation, blood sugar issues, cortisol, sex hormones, food sensitivities, and infections may affect thyroid physiology Why comprehensive lab testing may reveal patterns missed by basic panels The difference between food allergy testing and food sensitivity testing How lifestyle changes, nutrition, supplements, and retesting fit into functional medicine care Why patients may need to take a more active role in understanding their health Stay Connected & Explore Learn More About Dr. Kevin Smith & Metabolic Solutions: Dr. Kevin Smith / Metabolic Solutions: https://www.metabolicsolutions.net/ Free 2-Minute Metabolic Health Assessment: https://www.metabolicsolutions.net/metabolic-scorecard/ Chronic Conditions Center: https://www.chronicpa.com/ Connect with Conversations with a Chiropractor: Follow Us on YouTube: http://www.youtube.com/@ConversationswithaChiro Follow Dr. Stephanie on Facebook: https://www.facebook.com/wautierwellness Email for show-related inquiries and sponsorships: drstephaniewautier@yahoo.com Want to be a guest on Conversations with a Chiropractor? Send Stephanie Wautier a message on PodMatch, here: https://www.podmatch.com/hostdetailpreview/drstephanie Credits Podcast production by Brand|Sound. Start your podcast journey by emailing brandsoundpodcasts@gmail.com. Chapters 00:00 Introduction to Conversations with a Chiropractor 00:56 Meet Dr. Kevin Smith 01:55 Why Thyroid Health Is the Focus 02:15 Common Symptoms of Hypothyroidism 04:01 When Symptoms Persist but Labs Look Normal 05:13 Looking Beyond Basic Thyroid Testing 05:47 Hashimoto's Disease and Autoimmunity 07:15 Why the Immune System Matters in Thyroid Health 08:25 Thyroid Medication, Unresolved Symptoms, and the Bigger Pathway 09:04 The Brain, Pituitary Gland, TSH, T3, and T4 10:37 The Thyroid as the Body's Energy Regulator 11:48 Brain Fog, Mood, Gut Symptoms, and Cellular Energy 13:16 Triggers That Can Disrupt Thyroid Physiology 15:13 Hypothyroidism vs. Hyperthyroidism 16:14 Intake Forms, Questionnaires, and Foundational Labs 18:14 What Dr. Smith Looks for in Lab Work 19:53 Insurance, Coverage, and the Limits of Symptom Management 22:29 Managing Symptoms vs. Looking for Root Causes 23:30 Patients Who Feel Like They Are Out of Options 25:24 Medication Side Effects and Patient Education 27:26 Dr. Google, Food Testing, and Objective Data 29:36 IgG, IgE, and Food Sensitivity Testing 31:48 Delayed Reactions and the Long-Fuse Firecracker Analogy 34:43 Celiac Disease, Crohn's, Colitis, and Autoimmune Patterns 35:48 Treatment Through Lifestyle, Nutrition, and Supplements 37:51 Affordability, Priorities, and Investing in Health 40:23 Owning Your Health and Understanding the Problem 43:26 Chiropractic, Functional Medicine, and Knowing the Right Tool 45:11 How to Find Dr. Kevin Smith 46:26 Working With Patients Outside Pennsylvania 47:34 Final Thoughts and Closing

Low T3 Isn't a Conversion Problem… It's a Protective Response If your thyroid labs show low free T3 and high reverse T3, you've probably been told your body isn't converting thyroid hormone properly. So the solution becomes: add more T3, adjust medication, and try to "optimize" your numbers. But what if your body is doing exactly what it's supposed to do? In this episode of the Thyroid Answers Podcast, Dr. Eric Balcavage explains why low T3 and elevated reverse T3 are often signs of intentional, regulated metabolic downshifting… not dysfunction. You'll learn why thyroid hormone conversion is controlled at the tissue level, how your current physiological state influences what your body does with thyroid hormone, and why treating lab numbers without context often leads to temporary relief instead of long-term results. Dr. Balcavage also breaks down the difference between total and free thyroid hormones, how medication timing can skew lab results, and why ratios only matter when you understand the bigger picture. If you've been chasing "optimal" thyroid numbers but still feel tired, stuck, or unable to lose body fat… this episode will help you understand what your body is actually doing—and why forcing it to do more may be working against you. What You'll Learn: • Why low free T3 and high reverse T3 are often protective responses • The difference between total vs. free T4 and T3 (capacity vs. availability) • How thyroid conversion is regulated by deiodinase enzymes at the tissue level • Why reverse T3 is not a blocker, but a signal of adaptation • How your physiological "state" (resilient, strained, overloaded) impacts metabolism • Why adding more T3 often creates short-term relief, not long-term resolution • How medication timing can distort thyroid lab results • Why lab ratios require proper clinical context • The connection between metabolic demand, stress, and energy production • Where to focus instead: reducing demand and rebuilding capacity (sleep, nutrition, stress) Learn More About Dr. Eric Balcavage Dr. Eric Balcavage is the co-author of The Thyroid Debacle and the creator of: • State-Based Medicine™ • The Adaptive Thyroid Model™ • The Strategic Thyroid Solution™ His work focuses on helping patients and practitioners understand thyroid physiology through the lens of metabolic stress, adaptation, and whole-body regulation. Visit www.drericbalcavage.com to learn more.   Connect With Dr. Eric Balcavage Website: https://www.drbalcavage.com Instagram: https://www.instagram.com/drericbalcavage Facebook: https://www.facebook.com/drericbalcavage YouTube: https://www.youtube.com/@drericbalcavage If you enjoyed this episode, be sure to subscribe, leave a review, and share it with someone who may be struggling with thyroid issues or chronic fatigue.

In this powerful episode, Lisa Fischer sits down with Dr. Amie Hornaman to uncover why so many women are still misdiagnosed, dismissed, or improperly treated for thyroid conditions. From rapid weight gain and medical gaslighting to ineffective treatments like T4-only medications, Dr. Amie shares her personal journey and the science behind what actually works.     You'll learn why standard care often fails, the critical role of T3, and how to advocate for yourself when doctors won't listen. They also dive into the connection between thyroid health, hormones, metabolism, and even autoimmune conditions like Hashimoto's and PCOS.     If you've ever been told "your labs are normal" but still feel exhausted, this episode will open your eyes—and give you actionable solutions to finally feel like yourself again.    

In this podcast interview with Dr. Amie Hornaman, I dive into thyroid health, hypothyroidism, and Hashimoto's, uncovering why so many people feel fatigued, gain weight, and struggle with brain fog despite being told their labs are “normal.” We break down T3 vs T4, root causes of thyroid dysfunction, and the exact functional medicine strategies that actually restore metabolism and energy.I just released another video that walks you through exactly how to lose weight rapidly without wrecking your hormones or crashing your energy.Watch it here: ⁠https://youtu.be/iSpdK2vNjP0⁠GET A CUSTOMIZED WEIGHT LOSS PLAN: Have a free 1-on-1 call with our Expert Nutritionists

Esta madrugada, el MET, el Museo Metropolitano de Arte de Nueva York, ha celebrado su gala benéfica anual para recaudar fondos para el Costume Institute. Por ello, hemos invitado a Inés Lorenzo, directora de Vogue España, para que nos desvela los entresijos tanto del gran evento, como de la alfombra roja previa, que reúne a las celebridades en las emblemáticas escalinatas del museo. También hemos hablado con Carlos Lamela, uno de los arquitectos más prestigiosos de España y cofundador del estudio Lamela, responsable proyectos reconocidos a nivel internacional como el diseño de la T4 de Barajas o una de las remodelaciones del estadio Santiago Bernabéu.

This podcast episode gives nurses a practical, easy-to-apply overview of common thyroid disorders, focusing on how to recognize and manage both hypothyroidism and hyperthyroidism in clinical practice. It reviews key differences in presentation—such as fatigue, weight gain, and cold intolerance in hypothyroidism versus weight loss, tachycardia, and heat intolerance in hyperthyroidism—while connecting these symptoms to underlying physiology. Nurses will learn important medication considerations, including proper administration of levothyroxine and monitoring for adverse effects with methimazole. The episode also highlights critical safety topics like recognizing thyroid storm, interpreting lab values (TSH, T3, T4), and providing effective patient education. With real-world clinical pearls, this episode helps nurses build confidence in managing thyroid conditions across care settings. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Formula 1 presenter Steve Jones is the latest guest on a brand new series of the award-winning podcast Fuelling Around. The 49-year-old is best known for being the main presenter of Channel 4's coverage of Formula 1 and previously hosted shows such T4 and X factor USA.Steve joined Vicki and Dave to explain how he likes everything to be just right about his cars, and how he's managed to write 3 books while on the road with the F1 circus!

Most disciplined executives and entrepreneurs aren't struggling with fat loss because of effort or willpower. They're struggling because they're out of sequence—jumping straight to peptides, compounds, and advanced protocols before the three biological levers that actually drive fat loss are even stable.In this episode, Julian Hayes II breaks down the exact three mechanisms that determine whether your body gets lean and stays lean—and how to pull each one in the right direction before layering in anything advanced.You'll walk away understanding why fat loss is a sequencing problem, not a knowledge problem, and what it actually looks like to build a metabolic foundation that performs the way your business does. For executives and entrepreneurs operating in high-stakes environments, this episode connects biology directly to business performance.— Episode Chapter Big Ideas (timing may not be exact) —0:00 – Why disciplined high performers still don't look the part 1:57 – The three biological levers behind sustainable fat loss2:51 – About Julian and Executive Health3:26 – Who this conversation is actually for 4:49 – Lever 1: Nutrient Partitioning: where do your calories actually go?6:04 – The capital allocation analogy: investing in lean tissue vs. storing fat6:50 – The four factors that determine partitioning efficiency12:26 – Practical foundation: how to optimize partitioning before going advanced13:19 – Earning your carbs: the Charles Poliquin philosophy15:30 – GLP-1 receptor agonists and nutrient partitioning15:49 – Testosterone and hormonal optimization: Why hormones make everything go18:06 – Lever 2: Recovery Signaling: Where most high performers self-sabotage19:09 – What recovery signaling actually controls in a deficit19:33 – Cortisol21:02 – Growth hormone22:07 – Thyroid conversion: the T4 to T3 problem nobody talks about24:15 – HRV: your autonomic nervous system's engine light27:07 – Practical recovery: sleep timing and maximizing slow-wave GH pulses28:53 – Protein in a deficit: the primary defense against muscle loss29:39 – Electrolytes, magnesium, and why micronutrients matter more on GLPs32:51 – Advanced layer: CJC-1295 and Ipamorelin34:17 – Exogenous HGH: beyond bodybuilding34:54 – BPC-157 and TB-500: the gateway peptides for recovery35:58 – The 90/95 rule: foundation is the work, advanced tools are the amplifier36:34 – Lever 3: Appetite and Energy Regulation: the compliance lever37:22 – Why fat loss is a compliance problem, not a knowledge problem37:34 – Food noise is biological, not psychological38:51 – What poor appetite regulation actually costs executives40:24 – How aggressive deficits suppress testosterone41:15 – Performance as the feedback loop for energy regulation43:00 – Fiber, gut health, and natural GLP-1 secretion44:06 – Meal timing and circadian biology46:52 – Advanced layer: Semaglutide, Tirzepatide, and Retatrutide explained50:30 – Muscle loss, GI risk, and why lifestyle habits are the real variable51:24 – Genetics and fat loss52:47 – Low-dose Naltrexone54:19 – Thymosin Alpha-1 and emerging peptide research on energy regulation55:36 – Tying it all together: Foundation First, Amplification Second57:01 – The cost of skipping a sequence59:05 – The executive case for fat loss beyond aesthetics1:01:30 – How to work with Julian privately— Connect with Julian and Executive Health —LinkedIn — https://www.linkedin.com/in/julianhayesii/X — https://x.com/thejulianhayesReady to take your health, leadership, and performance to the next level? Book an exploratory call —https://www.executivehealth.io/contactWebsite — https://www.executivehealth.io/***DISCLAIMER: The information shared is not meant to treat or diagnose any condition. This is for educational, informational, and entertainment purposes. The content here is not intended to replace your relationship with your doctor and/or medical practitioner. Consult your provider before making any decisions.

Your metabolism slowing down in midlife isn't just about age.If your energy is lower, your weight isn't responding, and things that used to work no longer do… this may be a signaling issue, not a failure.In this episode, Janell explains how your thyroid regulates metabolism, why many women are told everything looks “normal” while still feeling off, and how stress, gut health, and environment all influence energy and weight.This conversation helps you move out of frustration and into understanding—so you can start supporting your body in a way that actually works.In This Episode, You'll Learn:• Why metabolism changes in midlife aren't just about age• How the thyroid regulates energy and weight• Why TSH alone doesn't tell the full story• The importance of T4 to T3 conversion• How stress and gut health impact metabolism• Why symptoms can persist even with medicationNext Step:If this conversation is resonating and you're starting to see that your metabolism might be responding to something deeper… there are two simple ways to move forward.If you're not quite sure what your body is doing yet, start with the Hormone Clarity Quiz:https://www.thetransformationlife.com/hormonequizIt will help you identify which pattern your body is primarily running right now.And if you're ready to begin supporting your metabolism in a more structured way, the Metabolic Jumpstart walks you through how to stabilize blood sugar, support your nervous system, and rebuild energy step by step:https://www.thetransformationlife.com/metabolic-jumpstartBecause this isn't about doing more…it's about doing what your body actually needs.

Why Thyroid Medication Rarely Fixes Fatigue Many people struggling with fatigue are told the same thing: your thyroid must be low. And if thyroid hormone controls metabolism, then increasing thyroid medication should restore energy… right? But thousands of patients discover something confusing. Their thyroid labs improve after starting medication, yet the fatigue remains. In some cases, the exhaustion actually gets worse. In this episode of the Thyroid Answers Podcast, Dr. Eric Balcavage explains why thyroid medication often fails to resolve fatigue and what may actually be driving low energy levels in the body. You'll learn why fatigue is often not caused by a simple thyroid hormone deficiency, why reduced T4-to-T3 conversion may be an adaptive response, and how metabolic capacity—not just hormone levels—determines how much energy your body can produce. Dr. Balcavage also breaks down the three most common thyroid treatment traps, explains why lab values can be misleading, and shares the better questions patients and practitioners should be asking when fatigue persists despite "optimized" thyroid labs. If you've been chasing lab numbers while still struggling with exhaustion, this episode will help you understand the deeper physiology behind thyroid fatigue and why restoring metabolic capacity is often the real solution. Learn More About Dr. Eric Balcavage Dr. Eric Balcavage is the co-author of The Thyroid Debacle and the creator of: • State-Based Medicine™ • The Adaptive Thyroid Model™ • The Strategic Thyroid Solution™ His work focuses on helping practitioners and patients better understand thyroid physiology, metabolic stress, and the root causes behind chronic health conditions. Resources Website: https://www.drericbalcavage.com Instagram: https://www.instagram.com/drericbalcavage To receive the Thyroid Labs Decoded guide, send Dr. Balcavage a DM on Instagram with the word LABS or request it through the contact form on the website.

What if “normal labs” aren't the same as feeling normal? In this eye-opening episode, we break down thyroidmaxxing—a smarter, more personalized approach to optimizing hypothyroidism treatment that goes far beyond the standard one-size-fits-all model. Because while medications like levothyroxine are considered the gold standard, many patients still struggle with fatigue, weight gain, and brain fog—even when their labs look “fine.”We explore what it really means to optimize your thyroid—from dialing in the right medication (T4, T3, or combination therapy) to identifying your optimal lab ranges, not just “in range.” You'll also learn how factors like stress, nutrition, metabolism, and even other hormones can make or break how you feel day to day—and why a truly effective treatment plan must be individualized to your body.If you've ever been told “your labs are normal” but still don't feel like yourself, this episode is your roadmap. 

Esta mañana, 14 de abril de 2026, hoy por Hoy ha despegado y aterrizado en la T4(cumple ahora 20 años) del Aeropuerto Internacional "Adolfo Suárez Madrid Barajas", un aeropuerto que tras la futura ampliación de esa zona y la T 1 pronto tendrá más de un millón de viajeros al mes. Lo ha explicado, junto a Nacho Carretero y Aitana Castaño (Comando Norte) su arquitecto, Carlos Lamela, quien entre otras muchas cosas ha destacado la importancia en la arquitectura de este lugar del bambú y de la luz que inunda lugares tradicionalmente opacos y cerrados como la estancia de la recogida de maletas. Junto a Mario Otero, el director del aeropuerto, hemos conocido el día a día de su máximo responsable. Con Eduardo Barba (Meterse en un jardín), desde esa terminal, hemos hablado de las flores más viajeras o con Martín Bianchi (15 minutos de fama), de la inevitable y no siempre deseable relación que existe entre los aeropuertos, los famosos y los paparazzis. 

Maurici Lucena, presidente y consejero delegado de AENA, nos cuenta muchos de los secretos y de los detalles de la T4 del aeropuerto Adolfo Suárez Madrid-Barajas, que este año celebra su 20 aniversario. Además, avanza algunas pistas de la ampliación de la terminal y del aeropuerto, que va a situar al de Madrid en uno de los más importantes del mundo.

Martín Bianchi lleva sus '15 minutos de fama' a la T4 para convertir el Aeropuerto de Adolfo Suárez Madrid-Barajas en un pasarela VIP de la crónica del corazón: el regreso estratégico de Juan Carlos I, los idiomas de Letizia Ortiz y los romances inesperados como el de María Carolina de Borbón-Dos Sicilias y Jordan Bardella.

Esta mañana, en el año en el que la T4 del Aeropuerto Internacional `Adolfo Suárez Madrid Barajas´ cumple 20 años, hemos hecho aterrizar, con Nacho Carretero y Aitana Castaño, el programa de hoy por Hoy en esta terminal, donde entre otros protagonistas hemos charlado con su arquitecto, Carlos Lamela, quien nos ha definido una estructura, bien protagonizada por el bambú y la luz natural o a su director Mario Otero, quien define el aeropuerto como una ciudad en la que "siempre hay un plan B, un plan C y un Plan D y en el que lo único que me quita el sueño es no poder cumplir las expectativas de un pasajero por el que pasan a diario, sólo en la T4,  más de cien mil". 

What a day for Rory McIlroy (-12). He jumps out to a six-shot lead over Sam Burns (-6) and P. Reed (-6) while Shane Lowry (-5), Tommy Fleetwood (-5), and Justin Rose (-5) sit at T4. We walk you through all of the day's action: Stories of the Day, Down the Leaderboard, Big's Top 10, on-site observations with Soly & Neil, news & notes, and a whole bunch more! Presented by Titleist. Titleist - #1 Ball in Golf High Noon - Sun's Up! Arccos - NLU15 for 15% off at https://www.arccosgolf.com/ Looking to travel this year, check out East Sands Golf Co.: https://www.eastsandsgolf.co/nlu Join us in our support of the Evans Scholars Foundation: https://nolayingup.com/esf The NLU email newsletter: bi-monthly updates on all things NLU: https://newsletter.nolayingup.com/subscribe Join The No Laying Up Nest: https://nolayingup.com/join Learn more about your ad choices. Visit megaphone.fm/adchoices

Writer, comedian, and actor Olivia Lee (Balls of Steel, T4, The Tonight Show with Jay Leno) and writer, actor, podcaster, and comedian Cariad Lloyd (Griefcast, Sara & Cariad's Weirdos Book Club podcasts, Austentatious, and new book Where Did She Go?) for an episode that asks, where even are the neurotypicals?Cariad shares about her days doing character comedy, specifically her alter ego the Sanitary Bag Lady - a woman dressed as a bathroom disposal bag who screams at men about periods - and the night a man in the audience stood up to fight her. Olivia tells us about a perimenopause-induced sleep crisis, a celebrity neighbour's black market melatonin, and no memory of whether she'd dropped her children off at school.Jameela tells the stories of a lamp falling out of the sky and splitting her head open at 19, her caffeine withdrawal hallucinations during her own T4 days, and why marshmallow crocodiles will always be her #1.Plus high speed childbirth, music festival flatulence, 50 hour marathon improv psychosis, and a husband who was still holding his salt beef sandwich when the crash team arrived.You can find Cariad on Instagram at @cariadlloyd. Austentatious perform regularly in London's West End and on tour. Cariad's new children's book Where Did She Go? is out in May 2026 and available for pre-order now.You can find Olivia on Instagram at @olivialeetv. Her special, Mindful Mum "was the first album of its kind, featuring x-rated angry meditation tracks." She is currently performing live comedy, writing scripts and staying away from Planet Organic.Jameela's Substack is A Low Desire To Please, you can also find her on Instagram, TikTok and YouTube.Our consulting producer is Colin Anderson.Wrong Turns was created and produced by Jameela Jamil and Stewart Bailey. Hosted on Acast. See acast.com/privacy for more information.

Deb (00:03.606)Within the next seven months, up to 1.5 million Americans could lose access to a medication that they’ve relied on for decades. Not because it’s dangerous, but because a pharmaceutical giant may have lobbied the FDA to eliminate their competition. And if you’re one of them, your doctor may already have told you about this issue and stopped prescribing it.This isn’t a conspiracy theory. This is documented in federal court filings. This is happening right now. And the company that stands to profit, well, they’re the same ones manufacturing the only product that might survive.Today on Let’s Talk Wellness Now, we’re exposing the desiccated thyroid extract crisis, the corporate manipulation behind it, and what you need to do right now to protect your health. Stay with me because I’m about to share what could save your access to the medication keeping you alive.Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, expose regulatory capture in healthcare, and empower you with the tools to advocate for yourself. I’m Dr. Deb, naturopathic doctor, your medical detective, and today we’re diving into one of the most consequential and corrupt healthcare decisions affecting patients right now. If you or someone you love takes Armour thyroid, NP thyroid, or any desiccated thyroid extract,for hypothyroidism or if you’ve struggled to find a thyroid medication that actually works for your body, this episode is absolutely critical. And if you have celiac disease, gluten sensitivity or corn allergies, what I’m about to reveal will make your blood boil. Now grab your cup of coffee, don’t forget your notebook and settle in because what’s happening to this medication right now is a masterclass in how pharmaceutical companies use regular Deb (02:06.544)agencies to eliminate competition, control markets, and price gouge patients. And I have all the receipts. Deb (02:20.982)Let me start with what might surprise you. Desiccated thyroid extract, or DTE as we call it, is actually one of the most oldest thyroid medications in the world. And I mean old. From the 1890s through 1970, this was the standard treatment for hypothyroidism.Now let’s really dive into that. From the 1890s to the 1970s, this was standard hypothyroidism treatment.In 1965 alone, and this is documented in peer-reviewed literature published in the Journal of Clinical Endocrinology and Metabolism, approximately four out of every five prescriptions for thyroid hormone in the United States were of natural desiccated thyroid preparations.The Journal of Clinical Endocrinology and Metabolism is a very high-end journal. Now think about that. This wasn’t some fringe therapy. This was mainstream medicine. Armour Thyroid, the most recognizable brand name, has been manufactured since the early 1900s, well over a century ago.and this is cited again in NIH bookshelf. When the FDA was officially established in 1938, Arbor thyroid was already on the market. And this is important and I want you to understand why. Under the federal Food, Drug and Cosmetic Act, any drug that was already being marketed before 1938 was automatically grandfathered into the system. That means it didn’t have to Deb (04:08.112)go through the formal FDA approval process. And this again is cited under the Federal Food, Drug and Cosmetic Act, grandfathered drugs and exemptions. And this is crucial to understanding what happens next. By the 1970s, synthetic levothyroxine, brand name Synthroid and generics became the preferred treatment. Hmm, wonder why?It was easier to standardize, came into consistent doses, and worked well for most patients, and could be mass manufactured. By the 1980s, levothyroxine had largely replaced desiccated thyroid in clinical practice, according to the American Thyroid Association 2014 guidelines for the treatment of hypothyroidism. But here’s what matters. Some patients…a very significant minority of them, never felt right on levothyroxine alone. Despite their lab work looking normal, they still had fatigue, brain fog, weight gain, cold intolerance, and depression.These patients often found relief when they switched back to their desiccated thyroid, which contains both T4 and T3 hormones, the way human thyroid naturally produces them. And this is not anecdotal. This is documented in randomized double-blind crossover studies published in Endocrine Practice.For decades, that was fine. Their doctors prescribed it, insurance sometimes covered it, patients were getting better, and the system worked really well. Until August 6th of 2025, just a short time ago, everything changed. On that date, the FDA sent letters to manufacturers, importers, and distributors of desiccated thyroid extract products stating that these medications would need an approval. Deb (06:04.654)a biologics licensed application, a BLA, to remain legally on the market. And this is cited in the FDA’s official statement, FDA’s actions to address unapproved thyroid medications. understand it says unapproved thyroid medications. However, desiccated thyroid, specifically Armour, has been approved since 1938. And this was dated August 6th through 7th, 2025.This wasn’t a guideline. This wasn’t a suggestion. It was an endorsement of action. And the timeline they gave them? Well, just 12 months to transition patients to another medication before enforcement action could begin.This was also cited by an FDA notice to the industry, animal derived thyroid products notice to industry, August 6th, 2025. Now do the math, that means August 2026, seven months from now, 1.5 million Americans currently taking this medication. And this number comes from the FDA official statement, citing that it’s an estimation of 1.5 million patients receiving prescriptions for these medications.could potentially lose their thyroid access. Now, here’s where it gets interesting. The FDA didn’t wake up in August of 2025 and decide to regulate desiccated thyroid after a century. This decision has a much longer backstory. And understanding that backstory is critical to understanding what’s really happening in this industry.The shift started in 2022. Back in September of 2022, over three years ago, an FDA branch chief sent a letter to the National Associations of Boards of Pharmacy noting that the agency had decided to designate DTE as a biological product, which would affect its eligibility for compounding. Deb (08:13.972)This also is cited in an FDA letter to the National Association of Boards of Pharmacy September 2022.Then two months later, in November of 2022, the FDA’s Office of Compounding Quality and Compliance sent a softer letter acknowledging that many Americans take medication to treat hypothyroidism and some choose to take DTE products. The letter stated that the FDA would focus enforcement on cases that pose the greatest public health risks, such as serious adverse offense or serious product quality or adulteration.also is cited by an FDA letter from Francis G. Bromel, the director, Office of Compounding Quality and Compliance, November of 2022. Now, let me just think about this for a second. If this drug has been on the market since the 1800s, been FDA approved since 1938, would we not have seen a health crisis long before 2022?I honestly don’t know of any other drug that’s been around this long that’s used by this many people. Now granted, I haven’t done the research on it either, which I can do for you guys, but I’m just thinking if a drug is on the market today and it causes harm, it doesn’t make it three years, five years before you see lawsuits everywhere. Why are there no lawsuits on this drug? Why are there no major reactions that people are seen having?Hmm, just thought. But here’s the pattern. The FDA was already laying the groundwork back in 2022, testing the waters, signaling where this was headed. The August 2025 action. Then this came down. Deb (10:09.806)August 6, 2025, the FDA announced its position publicly and sent formal letters to all DTE manufacturers, importers, and distributors. This was cited by the FDA Enforcement Action August 6, 2025, letters to manufacturers, importers, distributions of DTE products. The agency stated several concerns. First, DTE products have experienced quality and dosing issues.The FDA cited, and I’m quoting directly from their statement, over 500 adverse events reported associated with DTE products from 1968 to 2025. From 1968 to 2025, we had 500 adverse reactions? What is that math equate to?A couple a year? Come on guys, this is insane! With a substantial increase, you, between 2019 and 2020 that the agency suggested was related to voluntary recalls of sub-potent or super-potent products.This was cited in the FDA statement, over 500 adverse events reported associated with ADT products from 1968 through 2025.Second, the agency expressed concern about batch inconsistency. According to the FDA’s official statements, tablets made from the same manufacturing batches may not always provide the same thyroid hormone levels. Okay, this was cited in the FDA statement, tablets made from the same manufacturing batches may not always provide the same thyroid hormone levels. Thirdly, and I want to actually let’s back up. I want you to remember I said that Deb (12:11.216)because further down in this podcast, we’re going to talk about this. This is an important point to remember. Thirdly, the agency raised concerns about potential impurities from animal source material, including potential for viral contamination due to the animal source and supraphysiological levels of T3.the FDA statement on impurities, viral contamination and super physiological T3 levels. Now I will tell you, I’ve been prescribing armarithograde for 20 years. I’ve rarely seen a super physiological dose given of T3 in lab results, unless the patient takes their medication like four or five hours before you do the blood test, then you’ll see a false rise because you’re actually seeing the medication. You’re not seeing people walking aroundsuperphysiological T3 levels. Nobody would like that feeling. So anyway, I digress. Now let me pause here because this is where I need to give you some context that the FDA hasn’t quite emphasized yet. Of course, we have another connection and it is the China connection.So the FDA’s concerns about contaminated drugs and quality issues don’t exist in a vacuum. In 2024, the U.S. over 828,000 metric tons of pharmaceuticals, seven times the level from 2000. And here’s the kicker. China and India supply the majority of active pharmaceutical ingredients. APIs for U.S. generics accounting for 70 to 80 % of the total genericdrug supply. According to Reuters industry report in 2024, they state that China supplies 82 % of the APIs for critical drugs. Deb (14:08.204)Got to question that, right? Why are we giving all of our drug formulas to China and allowing them to import them into our country? In fact, roughly 20 % of the critical drugs have APIs exclusively sourced from China. And China controls 80 to 90 % of the global production for antibiotics and other key compounds. This was also cited by Reuters industry data thatcontrols 80 to 90 percent of the global production for antibiotics and other key compounds. Now just think about this. They control 80 to 90 percent of our medication. They control 20 percent of our critical drugs and we just put what kind of tariff on them? Hmm.In 2025 alone, the FDA issued multiple warning letters to foreign manufacturers for contamination issues and failure to follow good manufacturing practices. This is also cited by the FDA warning letters 2024 through 2025 and multiple citations to foreign manufacturing facilities. This is a systematic problem affecting the entire US drug supply, not just desiccated thyroid.So when the FDA suddenly became concerned about DTE quality and contamination, part of that concern was legitimate. But this is crucial. The same inconsistencies and contamination issues exist across the entire generic drug supply. And the FDA has not taken the same enforcement action against them. Let that sink in.They have not taken the same enforcement action against the other drug companies. So what’s behind all of this? Where is this all coming from? Hmm. Let’s address something directly, because you deserve to know it. And I’m going to cite my sources precisely so that when the medical boards have something to say about this, and they might, I have a documentation for every single word that I am about to speak. Deb (16:24.878)According to the court documents filed in October 2025, in the case ofa urine, a urine. I’m going to say that wrong. Pharmaceuticals versus Dr. George Tidmarsh from ABBV, the multinational pharmaceutical company that manufactures armor thyroid, reportedly petitioned the FDA in 2024, asking the agency to reclassify DTE as a biologic and to prohibit other manufacturers from selling unlicensed DTE products unless they havehad an investigational new drug application, we call this an IND, and a clinical development program aimed at eventual approval. This is cited in the court filing a Urena pharmaceuticals lawsuit versus Dr. George Tidmarsh, October 2025, reported by Fierce Pharma. Now let me explain why this matters and why this is one of the most brazen examples of regulatory capture I’ve ever seen in my career.AbbeVee is one of the world’s largest pharmaceutical companies. In 2024, they reported over $54 billion in revenue. Drop the mic on that one.They have the resources, the regulatory expertise, the legal teams, and the financial capacity to navigate a biologics license application process that costs between $500 million and $1 billion. Let that sink in. Deb (18:07.882)A drug that’s been on the market since the 1800s that was grandfathered in 1938 that’s making plenty of money right now. They’re going to spend 500 million to $1 billion to get a biologics license application. Why would they do that? Well, we’re about to find out. Most otherDTE manufacturers, smaller companies like Acela Pharmaceuticals, which makes NP-thyroid, and RLC Labs, which made WP-thyroid, do not have those same resources. And this is cited in Pharma Voice in 2025. Why a treatment older than the FDA is getting new regulatory scrutiny. So when you petition the FDA to reclassify a drug in a way that requires this type of expensivetime-consuming biological approval, you’re not just asking for safety. You’re asking to eliminate your competitors from the marketplace. Now, I want to be very precise here. These allegations are documented in federal court filings, and it hasn’t been approved in court. It’s also been reported by multiple industry sources, including Fierce Pharma. But I’m telling you,what has been reported in legal proceedings, not stating it as an absolute fact because you deserve to know the difference and because I have to protect my license. Now, what do we know for certain?AbbeVee is working on a biologics license application for Armour thyroid through clinical trials called Avantia. This is cited by the AbbeVee corporate statement 2025 Avantia clinical trial for Armour thyroid. A cell of pharmaceuticals has been pursuing BLA approval for NP thyroid for seven years since 2017 and it completed its phase two trials successfully in 2025. They’re now moving Deb (20:15.448)into Phase 3 trials. This is also cited by the Acela Pharmaceuticals CEO statement 2025 seven-year pursuit for BLA approval completed Phase 2 trials moving to Phase 3.RLC Labs, which manufactured WP thyroid, has made no public announcement about pursuing BLA approval and really probably don’t have a plan to do this since they’ve been off the market for some time now. About five years, I think maybe a little longer. Here’s the market manipulation.If only ABBV is successful and obtains a BLA approval for Armour thyroid, that company would effectively have a monopoly on the DDT market. And in pharmaceutical markets, monopolies historically lead to price increases.We’ve seen this pattern over and over again when turning pharmaceuticals acquired Daraprim and raised their price from $13.50 to $750 per tablet overnight. When Myelin raised EpiPen increased prices by 400 % when insulin manufacturers colluded to raise prices in lockstep. This is the playbook.use regulatory barriers to eliminate your competition and then exploit pricing power. For a drug that’s been on the market since the 1800s, guess corporate greed is everywhere. They’re not making enough money on this product already and they’re taking advantage of the rules that they can manipulate their competition by. And here’s what really makes me furious. The American Thyroid Association, the professional organization Deb (22:06.672)representing endocrinologists sent letters to the FDA commissioner on October 8th of 2025 and September 18th of 2025.advocating for continued patient access to DTEs. This is cited in the American Thyroid Association statement and letter to the FDA commissioner dated October 8th, 2025 and September 18th, 2025. The American Association of Clinical Endocrinologists issued a statement on September 9th of 2025 supporting equitable access and personalized medicine for DTE. This was also cited in the American AssociationAssociation of Clinical Endocrinologists, AACE, statement dated September 9th, 2025. Even the medical establishment, which has historically favored levothyroxine, is saying, wait, this is going too far. Patients need access to this medication. But the FDA is moving forward anyway. Why? Well, where does it always lead us? Follow the money trail.Okay, so I need to explain what a biologics license application actually is because this is where the rubber meets the road for what’s going to happen to pricing and availability. What is a BLA?A BLA is a biologics license application. It’s a formal request submitted to the FDA to market a biologic product in the United States. A biologic is defined under the Public Health Service Act section 351 as a product derived from or made using living material, in this case, animal thyroid glands. And this is cited in the FDA definition for biologic products. So they’re putting armor thyroid right Deb (23:57.377)right up with stem cells and exosomes. Think about that. Stem cells and exosomes cost thousands of dollars per application because of how they have to be harvested, stored, freezed, all of that. But we’re talking about a thyroid gland. Good Lord, people.Unlike regular drug applications for synthetic medications which follow a simpler pathway, the BLA process is designed for complex biological products like monoclonal antibodies, vaccines, and gene therapy products. It’s a much more expensive, much more time-consuming process. The BLA processis what manufacturers have to do. And we’re going to talk about that. So according to Reprocell and Forge Biologics analysis of the FDA’s BLA process, here’s what companies need to submit. First, they need to complete a clinical trial data, phase one, two, and three trials, proving safety and efficacy for desiccated thyroid. Haven’t we done that since it’s been on the market since the 1800s? Just saying.This means they have to conduct large randomized controlled trials comparing it to levothyroxine, measuring safety outcomes, efficacy outcomes, and quality of life metrics. Second,Chemistry, Manufacturing and Controls, CMC’s data. Detailed information about how the product is manufactured, quality control measures, stability testing and specifications that must be met for every batch. Third, preclinical and animal safety data. Fourth, labeling and product information. Now, I think we have labeling and product information. Deb (25:53.717)since the 1800s? But just saying. Fifth, they need Pharma Covigilance Plan, a detailed plan for monitoring safety after the product is on the market. Haven’t they had to do that since the 1800s? And they have to have a timeline. And this is the critical part. The FDA’s standard review time for a BLA is 10 months.That’s after the application is deemed complete and accepted for filing. So this is cited by the FDA standard review timeline, BLA submission, and FDA review.Now, before you even get to filing, you need to conduct the clinical trials and compile all the data that’s typically several years of work. How are you going to prove safety and effectiveness in a large clinical trial long term? What do they consider? What do they deem long term? Three months, six months, a year, two years. These companies had 10 months.Well, maybe 12. They did it a year in advance. But unless you knew this was coming, how are you going to put together a trial, enroll the people, have all the trial components set up and ready to go in less than 12 months unless you knew it was coming beforehand? Even ifhad started all their clinical trials in 2024, completing them, compiling the data, and getting a complete application ready for submission, this would likely take you through mid-2026, then add another 10 months for FDA review. We’re looking at 2027 at the earliest for most of these companies to receive a BLA application. Deb (27:54.319)But the FDA gave the manufacturers until August of 2026. That’s approximately 19 months from when the August 2025 letters were sent. Most companies cannot reasonably complete the BLA approval in that timeframe. And when I’m talking about the 19 months, I’m talking about the information they would have had earlier. Now the cost.This gets me even more frustrated. Why are we spending this kind of money? The BLL process is extraordinarily expensive. The current FDA user fee for a BLA submission is approximately $483,560 just for the filing fee. And this is cited at the FDA user fees prescription drug user fee rates for 2025.The full cost of conducting clinical trials, CMC studies, and all the supporting documentation typically ranges from $500 million to over $1 billion, depending on the scope of the trials and the complexity. And this is cited in JAMA’s network, Open2023. A cell of pharmaceuticals has been pursuing the BLA approval since 2017. That’s eight years. And it’s just now.moving into phase three trials with a planned enrollment of approximately 300 patients. This is cited by the Acela Pharmacies CEO statement of 2025. Now that’s unusual. That’s typical for this process. This is not unusual. This is typical for this process to take seven, 10 years to get approval for this. So if Abby’s the one that requested this,Abby V. And Acela started this in 2017. Was Abby V threatened by Acela that Acela might get this approval and it would be quietly done without anybody seeing it? And maybe Abby V would be left out of the market after a century? Who knows? It’s possible. Deb (30:13.112)But for smaller manufacturers without billions in revenue, this cost is completely prohibitive. And this is why this matters. When you push an old established medication through an extraordinary, expensive approval process with a compromised timeline, one of three things happen. First, only the largest companies can afford it, creating a monopoly. And when that happens, the company that holds the only approved product can set pricing withminimal competitive pressures. Two, smaller manufacturers can’t afford it and their products disappear and the market shrinks and access decreases. Three, we see a combination of both and who pays the price? Literally, patients do. Now here’s whereThere’s something I want you to really think about because this is where the regulatory argument falls apart when you look at it carefully. The FDA’s concern about DTE is that, and I’m quoting their official statement, tablets from the same manufacturing batches may not always provide the same thyroid hormone levels. This is from their FDA statement.And that’s a legitimate quality concern, right? It is. Thyroid medications have a narrow therapeutic window like any other hormone, meaning the difference between an effective dose and the dose that causes problems can be quite small. But here’s what the FDA doesn’t emphasize. Generic drugs have the exact same dosing inconsistency issue, and it’s considered acceptable and has been since we allowed generics on the market.So how does a generic drug dose work anyway? Well, for generic drugs to be approved as bioequivalent to a brand name medication, the FDA requires that the generic drugs bioavailability fall within 80 to 125 % of the brand name product. Isn’t that a dose inconsistency? Deb (32:22.894)from the brand name medication? 800 or sorry, 80 to 125%. According to the pharmacy times analysis of the FDA’s bioequivalent standards, the 80 to 125 % bioequivalence rule means that a generic drug can have 20 to 45 % variability compared to the original brand product.Now, most generics are much closer than that. The FDA study data shows that the mean difference for an AUC value between generic and reference products is about three and a half percent in the two year post-Waxman hatch period, and 80 % of the generics fall within a five percent range. But the FDA’s regulations allow for that much higher variability. And this is cited in an FDA study data mean difference for AUC.Now, let me put this in plain language. A patient could take a generic levothyroxine tablet where one batch provides, say, 75 micrograms of an active thyroid hormone. And the next batch from a different manufacturer, a different generic manufacturer, could provide up to 93.75 micrograms, 125 % of that 75. That’s an 18 microgram difference.in the same prescribed dose. Now, this is considered acceptable and patients tolerate it and this system works.Yet the FDA’s argument against DTE is that batch-to-batch inconsistency is unacceptable and requires this expensive biologic approval? That’s a double standard. So why is batch inconsistency acceptable for generic levothyroxine, but supposedly unacceptable for desiccated thyroid? I’ll give you the regulatory answer. Deb (34:29.366)because DDT is a biological product derived from an animal tissue and the FDA considers biological products to require more rigorous control. That’s the regulatory answer, but I’ll give you the real answer.because there’s no billion dollar pharmaceutical company with a patent pending on generic levothyroxine who petitioned the FDA to regulate their competitors more strictly. The inconsistency argument is legitimate, but it’s selectively applied. And that matters when you’re trying to understand whether this is really about patient safety or whether it’s about market control.Now I want to talk about something that hasn’t gotten nearly enough attention in this discussion and it’s something that makes me absolutely furious. What is Armour Thyroid? According to the official prescribing information published by AbbeV and available through rxabbev.com and the FDA’s daily med database, Armour Thyroid contains the following inactive ingredients. Calcium steroid,dextrose derived from corn, mycocrystalline cellulose,sodium starch glycolate and a opadri white coating. Now let’s talk about dextrose. Dextrose is a sugar derived from corn and while manufacturers claim that the corn derived dextrose in armor thyroid is gluten free, here’s the problem. Cross contamination during corn processing can introduce gluten proteins especially if the corn is processed in facilities that also handle Deb (36:18.808)wheat, barley, or rye. Corn sensitivity is extremely common in patients with celiac disease and non-celiac gluten sensitivity, and studies show that up to 50 % of the celiac patients react to corn proteins due to molecular mimicry, and the corn proteins look similar enough to gluten that the immune system attacks them. And this is cited by RestartMD.com.And here’s what’s documented in peer-reviewed medical literature in a 2023 case report published in Case Reports in Endocrinology. These researchers documented five patients with gluten intolerance or celiac who were taking natural desiccated thyroid. Three of those patients also reported lactose intolerance. Now these patients had to switch from DTE to liquid levothyroxine formulations to avoid the inactiveSo here’s my question. If AbbeV becomes the only manufacturer with an approved DTE product and their formulations contain corn-derived dextrose that triggers reactions in celiac patients, what are those patients supposed to do? They can’t take armor because of the corn. They can’t take compounded DTE because the FDA is banning compounding of these biologics. They can’t take NPKsor WP thyroid because those companies may not survive the BLA process. So they’re left with a synthetic version of levothyroxine which may not work for them.Now the NP thyroid and WP thyroid difference. Now here’s what’s interesting according to drugs.com comparison of inactive ingredients and P thyroid and P thyroid has calcium steroid dextrose also derived from corn, mineral oil, multi-crystalline cellulose. Deb (38:19.31)cross carmelicin sodium and a opadri to white. So NP thyroid also has corn-derived dextrose. WP thyroid on the other hand was specifically formulated to be hypoallergenic according to ROC labs, but it’s no longer available and its ingredients were inulin from chicory root and medium chain triglycerides. No corn, no gluten, no common allergies. So todayWe do not have a glandular thyroid, a DTE, that is not potentially contaminated with gluten. Yet, patients with autoimmune thyroid disease are supposed to avoid gluten.Now, some of these people can handle a DTE and many cannot, so that argument could be a mute point. But at the end of the day, the one product that we had that was designated for patients with multiple chemical sensitivities, celiac disease and coron allergies, has been off the market for a long time already.We have a monopoly problem. So if ABBV becomes the only approved manufacturer, patients with these celiac diseases and corn allergies will either be forced to take a medicine that makes them sick and triggers their immune reaction or switch to a synthetic that doesn’t adequately treat their hypothyroidism or choose to go without treatment. This is not hypothetical. This is real patients with real medical needs who are about to lose accessto the only formulation that works for their body. And the FDA’s response is silence. Deb (40:07.69)Now I want to highlight something that hasn’t gotten nearly enough attention in this discussion. Compounding pharmacies. What is a compounding pharmacy? Compounded medications are custom made by licensed pharmacists to meet a patient’s specific needs. Maybe you need a different strength that was commercially available, but you have an allergy to a filler or a dye in the commercial product. Maybe you need a liquid formulation or instead of a tablet or you need a capsule. That’s when compoundingin. And the FDA’s, this is the FDA’s definition of compounding. And for decades, compounding pharmacies have been making desiccated thyroid extract for patients who needed customization. Some patients couldn’t take the commercial products because of the dyes and the fillers, and some needed strengths that were not available. And these compounding pharmacies filled the gap.But reclassification changes everything. When the FDA reclassified DTE as a biologic in 2022 and reinforced that decision in August of 2025, explicitly stated, and I’m quoting directly from the FDA’s official statement, these unapproved animal-derived thyroid medications are not eligible for compounding because these products are regulated as biologic products under the Public Health Service Act.How can that be? These products have been approved since 1938 and the Biologics Act didn’t go into effect or doesn’t go into effect until August of 2026.So how in 2022 were they able to say that the compounding pharmacies could not make these products? Anyway, what this means is after August 2026, compounding pharmacies will no longer be permitted to compound a desiccated thyroid extract, even for patients with specific medical needs. Now, compounding pharmacies can still compound T4 and T3 separately, synthetic versions of levothyroxine and liothyronine, according to Deb (42:12.728)healing dose compounding pharmacy. These pharmacists can create custom ratios of these two synthetic hormones to approximate what a patient was receiving from a DTE. But that’s not the same thing. Some patients respond better to the whole DTE preparation than to a compounded synthetic combination. And for patients with specific allergies to standard fillers like your celiac patients that I just talked about, losing the ability to get a compounded DTE alternative isreal hardship. This is going to be a ripple effect. For a subset of patients, maybe 5 to 10 percent of those on DTE compounding was their lifeline and it was their way to get a medication formulation that worked for their unique body. When compounding goes away, these patients lose that option as well and for some it will be a significant problem. Now let’s talk about what this likely means for your wallet.The current pricing right now, according to SingleCare and GoodRx, Armour Thyroid costs approximately $150 to $157 for a 90-day supply of 60-milligram tablets, about $1.67 per tablet. With discount cards, some patients can get it down to $101 to $152 for a 90-day supply.Generic levon thyroxine costs about $70 for a 90 day supply, less than half that price. And p-thyroid costs approximately $133 for a 90 day supply of 60 milligrams with a discount card about $83 to $101.What happens after we get BLA approval? Well, here’s the pharmaceuticals pricing model. When a company spends 500 million to $1 billion to bring a product to market, including conducting massive clinical trials, the cost tens of millions of dollars they recoup in that investment through pricing power. And this is cited in the pharmaceutical pricing models. If ABBIEV is the only company with an approved BLA of DTE, Deb (44:18.248)They have pricing power. They don’t have competitors. They can set their price, whatever they want. And historically, when drugs transition from grandfather status, which is basically unregulated to formal formally approved status, prices often increase significantly, not always, but often. And typically they have to get re-approval for insurance. SoTouring Pharmaceuticals acquired DARPM and raised the price again from $1,350 to $750 overnight, a 5,000 % increase. This is the playbook.Let’s talk about insurance coverage. This is the other consideration. Insurance companies sometimes have different coverage policies for approved versions versus unapproved drugs. And right now, many insurance plans cover armor thyroid or NP thyroid, even though they’re technically unapproved because they’ve been on the market for decades and patients are on them. Once a drug becomes formally approved, insurance companies may have new contractual relationships, prior authorization requirements, or preferred drugs.list that could affect your coverage. If 1.5 million people have to get a prior auth for their insurance to cover this new medication, this is going to drive the doctor’s offices crazy. We do not have the staff to man this. We do not have the manpower. We do not have the time. This is going to interrupt people’s ability to get their medications. This is going to create chaos within the system. And some patients might see better coverage, but manymost likely are going to see worse coverage and some might find themselves in a situation where they need to try to get the drug approved first or get an approval for something else like levothyroxine and they’re going to have to document that it didn’t work and the documentation that they had from 20 years ago is probably not going to be enough because it’s not documented anywhere. It’s lost in the system after 10 years. So for patients the practical takeaway is expect Deb (46:25.774)a price increase. I would say possible, but I don’t think that’s true. think you’re going to see a price increase if they get approved. Expect possible insurance complexities, budget accordingly, talk to your insurance company now about what your coverage is going to look like in 2027 if they even know. And if you want my honest assessment of what is likely to happen,I’ll give you a scenario, 30 % likelihood. The FDA enforces the August 26 deadline and DTE products not approved by then are pulled from the market. Patients will have 30 to 90 days to transition to other medications. Some patients suffer significant symptom relapse. Compounding for DTE becomes illegal and this disruptiveness of the system creates a real hardship. Scenario two.which is 50 % likely. This is actually what the FDA commissioner, Marty McCreary suggested on August 13th of 2025 when he posted on social media. The FDA is committed to pursuing the first ever approval of desiccated thyroid access pending results of the ongoing clinical trials. In the meantime, we’ll ensure access for all Americans. Hopefully that continues. What this likely means is the FDA uses enforcement discretion to allow continuedsales while approvals are being pursued and the deadline gets extended. Maybe patients get access for another two to three years while companies work on a BLA approval. This would be the least disruptive scenario, but it’s also legally uncertain because the enforcement letters have been formally rescinded. And scenario three, which is 20 % likelihood, one or two companies get BLA approval. Those products stay on the market at higher product prices and companies, products, other companiescompanies, products are pulled, the market shrinks, availability is limited, prices are higher, but patients can still get something. This is likely if a seller successfully completes phase three trials for NP-thyroid. And my assessment is based on the regulatory language and the enforcement letters that have not been rescinded yet, that the pattern of FDA enforcement, I believe scenario two enforcement discretion with an extended time frame is most likely what we’re going to see. Deb (48:49.488)doesn’t mean patients should sit back and do nothing. It means you should be prepared for change while advocating for access. If you want to keep Arm or Thigh Right on the market, 1.5 million people need to start talking about this publicly and flooding our Congress people, Bobby Kennedy, the FDA, with what you want to see happen. We have the ability to shape this and to change this with our voice. But if we sit back on our laurels and we do absolutelynothing. What is going to happen is what the FDA wants to have happen and ABV wants to have happen because they’re going to simply think people don’t give a shit. And if the American people are going to be lazy and not want to step forward and actually start using their voice for some good and instead of just going to social media and bitching and hoping something is going to happen, well, then we’re going to get what we deserve. But if you start taking someaction and you start advocating for the things that you want. Contacting your representatives, contacting your U.S. tell them the FDA has done this. Many of them may not know this, may not be on their radar. Tell them what you want. Start going after this. Start writing to the FDA Commissioner’s Office. They have a website. They have a Commissioner’s Office at fda.hhs.gov. Be responsible.respectful, but be firm. Explain your scenario. How long you’ve been on DTE. Why levothyroxine doesn’t work. What symptoms you experience when not adequately treated. How this decision will affect your quality of life and your pocketbook. Let’s do something proactive. So let’s consider this. Moving forward, work with your provider who understands the regulatory landscape around DTE. You can discuss the evidence for and against combination therapy.You can monitor for thyroid function with free T3 and free T4 testing, not just TSH. If you’re willing to try individualized approaches, you can do that. If you need help finding a functional medicine provider who understands this issue, come to serenityhealthcarecenter.com or explorethevanari.com. It’s a self-directed functional medicine support group. And right now what is happening is going to shape how history Deb (51:19.024)is made with not just armor thyroid, but many drugs to come. And it is important for you to take action. So I want to thank you for joining me today on Let’s Talk Wellness Now. This episode is about far more than thyroid medication. It’s about your right to personalized medical treatment. It’s about your regulatory capture and corporate influence. And it’s about what happens when billion dollar companies shape healthcare policy in ways that reduce patient choice and increase their profits.this episode resonates with you or you know somebody who’s going to be affected by desiccated thyroid, please share it. Post it on social media, send it to your doctor, email it to your representatives, tag AbbeVee, tag FDA. Make noise because the only way we stop this is if we make it too politically costly for them to continue. Your voice truly matters. Your health truly matters and you deserve access to treatments that work best for your unique body.If you’re ready to explore comprehensive personalized health care that puts you in control, visit us at SerenityHealthCareCenter.com. Learn more about functional medicine approaches to thyroid and beyond and explore my new platform, Venari.com, which is a self-directed functional medicine tool. Thank you for joining me today. Until next time, I’m Dr. Deb reminding you, your health is your responsibility, your choice, and your right. Be well, stay informed, fight back.and I’ll see you in the next episode. And if you’re looking for a full citation list of this episode, you can head over to letstalkwellnessnow.com and I will post all the citations for you so you have them in your arsenal as well. Thank you again.The post Episode 259 – The Desiccated Thyroid Crisis: FDA's Unseen Impact & Corporate Manipulation first appeared on Let's Talk Wellness Now.

Millions of people, especially women are told their thyroid labs are “normal”… while they continue to struggle with fatigue, brain fog, weight gain, infertility, and depression.In this episode, thyroid expert McCall McPherson, PA-C, founder of Modern Thyroid Clinic, explains why so many thyroid conditions are being missed and what patients should actually be testing.We break down:• The biggest thyroid testing mistake doctors make• Why TSH alone isn't enough• The difference between T3 vs T4 thyroid hormones• Why many patients don't improve on Synthroid• Symptoms of thyroid dysfunction most people miss• The connection between thyroid, fertility, metabolism, and mental health• Why Hashimoto's often goes undiagnosed for years• The controversy around natural desiccated thyroid medicationsIf you've ever been told “your labs are normal” but you still feel terrible, this episode could explain why.

Your thyroid controls your energy, your metabolism, your testosterone, your mood, and your ability to think clearly. Most doctors are testing it wrong and treating it wrong, and this episode tells you exactly what to do instead. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with McCall McPherson, a physician associate, TEDx speaker, and founder of Modern Thyroid Clinic, Modern Weight Loss, and the advocacy platform Thyroid Nation. McPherson has been honored on the 2024 and 2025 Inc. 5000 lists and named a 2025 Top 500 Inc. Female Founder. She hosts the Modern Thyroid and Wellness podcast and built her entire practice around thyroid care after being failed by conventional medicine while managing her own hypothyroidism. She treats patients nationwide via telemedicine and has become one of the most trusted voices in functional medicine thyroid care. Dave and McCall expose why standard TSH-only testing catches just 1 to 2 percent of actual thyroid variation, why the medication most doctors prescribe (Synthroid/levothyroxine) fails a massive percentage of patients, and why T3 is the active hormone that mainstream medicine has been trained to fear without good reason. They also get into how fluoride in tap water, bromine in American wheat, mold exposure, dairy, gluten, and oxalates directly suppress thyroid function and drive autoimmunity. If you want to optimize your metabolism, protect your mitochondria, support brain optimization, and stop leaving your longevity on the table, thyroid is the first domino. This is essential listening for anyone serious about biohacking, human performance, anti-aging, functional medicine, supplements, sleep optimization, and using smarter not harder strategies to take control of your biology. You'll Learn: Why testing TSH alone misses thyroid dysfunction in the vast majority of people What a full thyroid panel actually includes and the optimal ranges for T4, T3, and reverse T3 Why T4-only medications like Synthroid fail and what works better How low thyroid directly tanks testosterone and libido in both men and women The environmental triggers destroying your thyroid, including fluoride, bromine, mold, and inflammatory foods How Hashimoto's connects to broader autoimmune risk and what drives it into remission Why kids are being misdiagnosed with ADHD when the real issue is hypothyroidism The supplements and cofactors (selenium, zinc, magnesium, ashwagandha, tyrosine) that support thyroid activation How thyroid optimization connects to metabolism, dementia prevention, cardiovascular health, and economic outcomes When to use T3 only vs. a T3/T4 combination, and how to know if your dose is off Thank you to our sponsors! TRU KAVA | Head to trukava.com and use code DAVE10 for 10% off. BEYOND Biohacking Conference 2026 | Register with code DAVE300 for $300 off https://beyondconference.com Our Place | Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide Puori | Go to Puori.com/DAVE or use code DAVE at checkout to get 32% off your Puori Fish Oil subscription. You save more than $18. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: McCall McPherson, Modern Thyroid Clinic, thyroid testing wrong, full thyroid panel, free T3, reverse T3, Synthroid failure, T3 vs T4, Hashimoto's remission, fluoride suppresses thyroid, thyroid low testosterone, thyroid ADHD, thyroid depression, hypothyroidism misdiagnosis, thyroid and metabolism, thyroid hair loss, functional medicine thyroid Resources: • Learn More About McCall's Work At: https://www.modernthyroidclinic.com/ • Get McCall's Thyroid Guide: https://gift.modernthyroidclinic.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 01:05 – Intro & Guest Background 02:26 – Dave & McCall's Thyroid Stories 05:26 – How Thyroid Hormones Work 12:51 – Why T4-Only Meds Fall Short 23:05 – Why Thyroid Dysfunction Is So Common 23:59 – Fluoride, Bromine & Environmental Triggers 26:39 – Thyroid & Low Testosterone 27:31 – Optimal Lab Ranges for TSH, T4 & T3 36:58 – Mold, Hashimoto's & Autoimmunity 44:44 – Thyroid, ADHD & Mental Performance 49:38 – Supplements for Thyroid Support 51:52 – Vitamin D & Circadian Rhythms 56:30 – T3 Safety Myths & Medical Misinformation 1:00:16 – Key Takeaways & Where to Get Help See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.