Bi-monthly review of the current Gastroenterology Literature
Manchester, New Hampshire
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Listeners of GI Pearls Podcast that love the show mention:Show Notes for Episode 63 of GI Pearls
Episode 62 Show Notes July 2023
Episode 61 Show Notes June 2023
Show Notes for GI Pearls Episode 60 What is the Prevalence of Clinically Significant Endoscopic Findings in Subjects With Dyspepsia? Updated Systematic Review and Meta-analysis – CGH Quality of upper GI endoscopy: a prospective cohort study on impact of endoscopist education – GIE Association between endoscopist specialty and colonoscopy quality: a systematic Review and meta-analysis.… Continue reading GI Pearls Episode 60
Show notes for Episode 59 GI Pearls Podcast Cannabidiol for Functional Dyspepsia With Normal Gastric Emptying: a RCT. – Am J Gastro Randomized Controlled Trial Investigating Cold Snare and Forceps Polypectomy among small POLYPs in Rates of Complete Resection: The TINYPOLYP Trial – Am J Gastro Vonoprazan triple and dual therapy for Hpylori infection in… Continue reading GI Pearls Episode 59 Short
Episode 58 Show notes Cold versus hot snare resection with or without submucosal injection of 6-15mm colorectal polyps: RCT. – GIE Prospective cohort study to investigate the safety of preoperative tumor necrosis factor inhibitor exposure in patients with inflammatory bowel disease undergoing intra-abdominal surgery. – Gastroenterology Clip Closure does not reduce risk of bleeding after… Continue reading GI Pearls Episode 58 Short
Articles discussed Clinically significant serrated polyp detection rates and risk for postcolonoscopy colorectal cancer: data from the New Hampshire Colonoscopy Registry – GIE Polyps seen but not removed during index colonoscopy: an underestimated inefficiency in endoscopy practice. – GIE Fecal Microbiota transplant is a good treatment for recurrent C.difficile and there were several randomized clinical… Continue reading GI Pearls Episode 57 Short
Episode 56 – New Short Format Articles discussed: Once-only colonoscopy or two rounds of faecal immunochemical testing 2 years apart for colorectal cancer screening: preliminary report of a randomised controlled trial – Lancet Gastro Hep Vedolizumab is associated with a lower risk of Serious Infectious than Anti-Tumor Factors Agents in Older Adults – CGH please… Continue reading Episode 56 – Short
Show notes for Episode 55 – June 2022 Pooled Rates of Adenoma Detection by Colonoscopy in Asymptomatic Average Risk Individuals with Positive Fecal Immunochemical Test: A Systematic Review and Meta-Analysis – GIE Long-Term Follow-up of the Italian Flexible Sigmoidoscopy Screening Trial – Annals of IM Recurrence of Colorectal neoplastic polyps after incomplete resection – annals of… Continue reading Episode 55 – June 2022 – Gastroenterology Literature Review
Show notes Episode 54 – May 2022 A Randomized Controlled Trial of Cold Snare Polypectomy Technique: Technique Matters More Than Snare Wire Diameter – Am J Gastro Outcomes for upper gastrointestinal bleeding during the first wave of the COVID-19 pandemic in the Toronto area – J Gastro and Hep Endoscopic Surveillance of Barrett's Esophagus –… Continue reading Episode 54 – May 2022 – Gastroenterology Literature Review
Show Notes for Episode 53 Lyophilised oral fecal microbiota transplantation for ulcerative colitis (LOTUS): a randomised, double-blind, placebo-controlled trial. – Lancet Gastro Effect of prophylactic endoscopic clip placement on clinically significant post-endoscopic mucosal resection bleeding in the right colon: a single centre, randomized controlled trial – Lancet Gastro Feasibility and diagnostic yield of small-bowel capsule… Continue reading Episode 53 – February 2022 – Gastroenterology Literature Review
Episode 52 Show notes Immediate versus Postponed Intervention for Infected Necrotizing Pancreatitis – NEJM Benchmarking Adenoma Detection Rates for Colonoscopy: Results From a US-Based Registry – Am J Gastro Colonoscopy-related Mortality in a Fecal-Immunochemical Test-based Colorectal Cancer Screening Program – CGH AGA Clinical Practice Update on Endoscopic Surveillance and Management of Colorectal Dysplasia in IBD… Continue reading Episode 52 – November 2021 – Gastroenterology Literature Review
Show notes for Episode 51 Role of routine second-look endoscopy in patients with acute peptic ulcer bleeding: meta-analysis of randomized controlled trials- GIE A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults with Crohn's Disease – Gastroenterology Comparative effectiveness and harms of antibiotics for outpatient diverticulitis. – Annals of IM… Continue reading Episode 51 – September 2021 – Gastroenterology Literature Review
Histologic Changes caused by Injection of a novel submucosal lifting agent for endoscopic resection in GI lesions. – GIE Prevalence of Barrett’s Esophagus and performance of societal screening guidelines in an unreferred Primary care Population of US veterans. – GIE The usefulness of olive oil enema in children with severe chronic constipation – J Ped… Continue reading Episode 50 – May 2021 – Gastroenterology Literature Review
Show notes for Episode 49 for April 2021 Effectiveness of Oral Vancomycin for Prevention of Healtchare Facility-onset C.diff infection in Targeted Patients during Systemic antibiotic Exposure – Clinical ID The Detrimental Effects of oral Vancomycin – Letter to Editor – Clinical ID Linked color imaging focused on Neoplasm detection in the Upper GI tract –… Continue reading Episode 49 – March 2021 – Gastroenterology Literature Review
Show notes for Episode 48 March 2021 Younger physicians and longer withdwaral times are associated with detection of advanced neoplasia in a large community practice. – CGH It’s All The RAVE: Time to Give up on “Chronic Radiation Proctitis” Misnomer – Gastroenterology Local immune response to food antigens drives meal-induced abdominal pain – Nature Prevalence… Continue reading Episode 48 – March 2021 – Gastroenterology Literature Review
Show notes for Episode 47, January 2021 Endoscopic Recognition and management strategies for Malignant Colorectal Polyps: Recommendation of the US Multi-Society Task force on Colorectal Cancer – GIE Polyp morphology: an interobserver evaluation for the Paris classification among international experts – AmJ Gastro Outcomes in lower GI bleeding comparing weekend with weekday admission. – GIE… Continue reading Episode 47 – January 2020 – Gastroenterology Literature Review
Show notes for Episode 46 for December 2020 Sequential endoscopist-driven phone calls improve capture rate of adverse events after ERCP: a prospective study – GIE Regular use of proton pump inhibitors and risk of type 2 diabetes: results from three prospective cohort studies – GUT Long-Term Consequences of Undiagnosed Celiac seropositivity – Am J Gastro Hyperbaric… Continue reading GI Pearls – December 2020 – Episode 46 Gastroenterology Literature Review
Show notes for Episode 45 for November 2020 Evaluation of Acute Mountain Sickness by Unsedated Transnasal Esophagogastroduodenoscopy at High Altitude – CGH Early Colonoscopy Does Not Improve Outcomes of Patients With Lower Gastrointestinal Bleeding: SRM – CGH Adverse Events After Inpatient Colonoscopy in Octogenarians – J of Clinical Gastro Comparative Efficacy of Drugs for the Treatment… Continue reading GI Pearls – November 2020 – Episode 45 Gastroenterology Literature Review
Show Notes for October 2020 – Episode 44 A Quarter of Participants With Advanced Neoplasia Have Discordant Results From 2-Sample Fecal Immunochemical Tests for Colorectal Cancer Screening – CGH Assessment of Clinical Conditions Associated with Splenic Infarction in Adult Patients – JAMA Internal Medicine Unsedated colonoscopy – impact on quality indicators – Dig Dis Sci The effect… Continue reading GI Pearls – October 2020 – Episode 44 Gastroenterology Literature Review
Show notes for Episodes 43 – September 2020 Levels of Vitamin D are low after Crohn’s disease is established but not before – CGH Rapid recurrence of EOE activity after successful treatment in the observational phase of a randomised trial. – CGH Clinical outcomes of adults with eosinophilic esophagitis with severe stricture. – GIE Quality… Continue reading GI Pearls – September 2020 – Episode 43 Gastroenterology Literature Review
Show notes for Episodes 42 – July/August 2020 Use of total underwater colonoscopy to navigate endoscopic challenges – CGH Performance of radiographic imaging after incomplete colonoscopy for non-malignant causes in clinical practice. – GIE Cognitive Deficit and white matter changes in persons with celiac disease: a population based study. -Gastroenterology Endoscopic gastric body plication for… Continue reading GI Pearls – July 2020 – Episode 42 Gastroenterology Literature Review
Show notes for Episodes 41 – June 2020 Discrepancy between self-reported and actual colonoscopy polypectomy practices for the removal of small polyps – GIE AGA Guidelines on the management of Moderate to Severe Ulcerative Colitis – Gastro Resistance training increases muscle strength and muscle size in patients with liver cirrhosis. – CGH Reduced incidence of… Continue reading GI Pearls – June 2020 – Episode 41 Gastroenterology Literature Review
Show notes for Episodes 40 – May 2020 Choosing a prokinetic for your patient beyond metoclopramide – AmJ Gastro Ultraprocessed Food Consumption and Risk of T2DM among participants of the NutriNet-Sante Prospective Cohort – JAMA Int Med Diagnosis and Treatment of Clostridioides (Clostridium) difficile Infection in Adults in 2020 – JAMA Clinical importance of cold polypectomy… Continue reading GI Pearls – May 2020 – Episode 40 Gastroenterology Literature Review
Show notes for Episodes 39 – February-March 2020 Prevalence of colorectal cancer and advanced adenoma in patients with acute diverticulitis – GIE Pancreatic tuberculosis: A systematic review of symptoms, diagnosis and treatment – UEGJournal Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastro… Continue reading GI Pearls – March/April 2020 – Episode 39 Gastroenterology Literature Review
Show notes for Episodes 38 – January 2020 ASGE review of adverse events in colonoscopy – GIE Endoscopic or Surgical Myotomy in Patients with Idiopathic Achalasia – NEJM Relationship Between Recreational Marijuana Use and Bowel Function in a Nationwide Cohort Study – Am J gastro Circulating tumor DNA methylation profiles enable early diagnosis, prognosis prediction, and screening… Continue reading GI Pearls – January 2020 – Episode 38 Gastroenterology Literature Review
Show Notes for December 2019 – Episode 37 Assessment of Publication Trends of Systematic Reviews and RCTs – JAMA Int Med. Association between Hpylori exposure and decreased odds of EOE – CGH Effect of anti-Hpylori therapy on incidence of autoimmune diseases, – CGH AGA Practice Update on Surveillance for cancer in patients with PSC –… Continue reading GI Pearls – December 2019 – Episode 37 Gastroenterology Literature Review
Show Notes for November 2019 – Episode 36 Detection of Various Microplastics in Human stool – Annals of int Med Herpes Zoster in Tofacitinib: Risk is Further Increased with Glucocorticoids but not Methotrexate – Arthritis Care Res Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae – Cell Incidence of and Risk Factors for Hepatic Encephalopathy in a Population-Based… Continue reading GI Pearls – November 2019 – Episode 36 Gastroenterology Literature Review
Show Notes for Oct 2019 – Episode 35 Appropriate therapeutic drug monitoring of Biologic agents for Patients with IBD – CGH The View from Europe – TDM – CGH Cold snare vs Heparin bridging and hot snare polypectomy in patients on anticoagulants with subcentimeter polyps. – Annals of int Med. High-Dose Vitamin D Supplementation on… Continue reading GI Pearls – October 2019 – Episode 35 Gastroenterology Literature Review
Discussing #FMT, Immunizations in #IBD patients, #ColonCancer guidelines, #DILI and much more!
Show Notes for June 2019 – Episode 33 Epidemiology and implications of concurrent diagnosis of EOE and IBD – Gut Risk of Cdiff Infection with Systemic Antimicrobial Therapy Following Successful FMT – Dig Dis Sci Safety of Endoscopy in cancer patients with thrombocytopenia and neutropenia – GIE Same-Day vs Different-Day Elective Upper and Lower Endoscopic Procedures… Continue reading GI Pearls – June 2019 – Episode 33 Gastroenterology Literature Review
Show Notes for May 2019 – Episode 32 Risk of postpolypectomy bleeding with uninterrupted clopidogrel therapy- an industry-indepentend, double-blind, randomized trial. – Gastroenterology Personalised surveillance for serrated polyposis syndrome: results from a prospective 5-year international cohort study – GUT Cold snare endoscopic resection of nonpedunculated colorectal polyps larger than 10mm: A systematic review and pooled… Continue reading GI Pearls – May 2019 – Episode 32 Gastroenterology Literature Review
Show Notes for April 2019 – Episode 31 Prediction of individuals at high absolute risk of esophageal squamous cell carcinoma – GIE Updates on Gastric Intestinal Metaplasia – Digestive Diseases Sci Thermal ablation of mucosal defect margins reduces adenoma recurrence after colonic EMR – Gastro Transfusion Strategies for Acute Upper Gastrointestinal Bleeding – NEJM Effect… Continue reading GI Pearls – April 2019 – Episode 31 Gastroenterology Literature Review
Show Notes for March 2019 – Episode 30 Sorry, but I was sick, so episode is shorter, and … late. Evaluation of adenomas per colonoscopy and adenomas per positive participant as new quality parameters in screening colonoscopy – GIE Adherence to Recommended Inpatient Hepatic Encephalopathy Workup – J Hosp Med Clinical ipact and Safety of Anticoagulants… Continue reading GI Pearls – March 2019 – Episode 30 Gastroenterology Literature Review
Show Notes for February 2019 – Episode 29 Effect of FMT on 8-week remission in patients with Ulcerative Colitis – RCT – JAMA Inflammatory bowel disease increases the risk of Parkinson’s disease – Gut Predictors of Metastases in Rectal Neuroendocrine Tumors: Results of a National Cohort Study – Dis Colon Rectum. Long-term Risk of Colorectal Cancer and Related Deaths… Continue reading GI Pearls – February 2019 – Episode 29 Gastroenterology Literature Review
Show Notes for January 2019 – Episode 28 Diagnosis and treatment of definitive diverticular hemorrhage – AmJGastro Proton-pump inhibitor prophylaxis in the ICU – NEJM Effectiveness and Safety of Reference Infliximab and Biosimilar in Crohn Disease: A French Equivalence Study – Annals of IM Laparoscopic magnetic sphincter augmentation versus double-dose PPI for GERD, randomized controlled trial –… Continue reading GI Pearls – January 2019 – Episode 28 Gastroenterology Literature Review
Show Notes for December 2018 – Episode 27 Efficacy of ustekinumab for inducing endoscopic healing in patients with Crohn’s disease – Gastro Association of Oral Anticoagulants and Proton Pump Inhibitor Cotherapy With Hospitalization for Upper Gastrointestinal Tract Bleeding – JAMA Clinician Guide to Microbiome Testing – Dig Dis Sci Stopping 5-ASA in patients with UC… Continue reading GI Pearls – December 2018 – Episode 27 Gastroenterology Literature Review
Show Notes for November 2018 – Episode 26 I’ve changed the intro music, obviously, let me know if you are annoyed by it or like it. Here is the list of papers: Acute Liver Failure of Indeterminate Etiology – Am J Gastro Efficacy of G CSF and NAC in patients with severe alcoholic hepatitis –… Continue reading GI Pearls – November 2018 – Episode 26 Gastroenterology Literature Review
Show Notes for October 2018 – Episode 25 Also, please sign up for the mailing list on the website at www.gipearls.com Complications of antireflux surgery – Am J Gastro Helicobacter Pylori infection is associated with reduced risk of Barrett’s – Am J Gastro Reverse Hybrid and Bismuth therapy for Hpylori infection – CGH Long-term outcomes of… Continue reading GI Pearls – October 2018 – Episode 25 Gastroenterology Literature Review
Show Notes for September 2018 – Episode 24 Association between portosystemic shunts and increased complications and mortality in patients with cirrhosis – Gastro Safety and efficacy of elobixibat for chronic constipation– The Lancet: Gastro Oral Anticoagulation in Patients With Liver Disease – JACC Risk of Serious and Opportunistic Infections Associated With Treatment of Inflammatory Bowel Diseases –… Continue reading GI Pearls – September 2018 – Episode 24 Gastroenterology Literature Review
Show Notes for August 2018 – Episode 23 Long-term effectiveness of Sigmoidoscopy Screening on Colorectal cancer Incidence and mortality in Women and Men – Annals of IM Enteral nutriton and quality of life in patients undergoing chemoradiotehrapy for esophageal carcinoma. – GIE Outcomes of endoscopic intervention for overt GI bleeding in severe thrombocytopenia – GIE… Continue reading GI Pearls – August 2018 – Episode 23
Show Notes for May 2018 – Episode 22 – Peptic ulcers, Infections in IBD, EOE, dyspepsia, Infliximab, Pancreatic cysts. etc. Email me – info@gipearls.com if you want to meet up at DDW Effects of Gastroprotectant drugs for the prevention and treatment of peptic ulcer disease and its complications: a meta-analysis of randomised trials – Lancet Gastro… Continue reading GI Pearls – May 2018 – Episode 22
Show Notes for April 2018 – Episode 21 Use of N-acectylcysteine plus simethicone to improve mucosal visibility during upper GI endoscopy: a double-blind, randomized controlled trial – GIE An International multicenter study evaluating the clinical efficacy and safety of POEM in octagenarians – GIE Nut Consumption and Survival in Patients With Stage III Colon Cancer:… Continue reading GI Pearls – April 2018 – Episode 21
Show Notes for April 2018 – Episode 20 Sorry for Audio Quality. I had a cold. Volatile Organic Compounds in Feces Associate With Response to Dietary Intervention in Patients With Irritable Bowel Syndrome – CGH Helicobacter pylori Eradication Reduces Risk for Metachronous Gastric Cancer in High-Risk Patients – NEJM Eosinophilic gastroenteritis and other eosinophilic gut diseases distal… Continue reading GI Pearls – March 2018 – Episode 20
Show Notes for March 2018 – Episode 18 On this epsiode I interview Jay Luther, MD from Massachusetts General Hospital on his Editorial on liver transplantation for alcoholic hepatitis. Other papers: Lesions of all types exist in colon polyps of all sizes. – Am J Gastro Abdominal Pain in the Roux-en-Y Gastric Bypass Patient –… Continue reading GI Pearls – March 2018 – Episode 19
Show Notes for March 2018 – Episode 18 Effect of Hot Tea Consumption and Its Interactions With Alcohol and Tobacco Use on the Risk for Esophageal Cancer – Ann Int Med IDSA guidelines for C.diff – IDSA Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults – JAMA Patients with familial adenomatous polyposis harbor… Continue reading GI Pearls – March 2018 – Episode 18
Show Notes for February 2018 – Episode 17 Cap cuff-assisted colonoscopy versus standard colonoscopy for adenoma detection: a randomized back-to-back study – GIE Risk of Clostridium difficile infection in Patients with Celiac Disease – Am J Gastro Faecal microbiota transplantation versus placebo for moderate-to-severe irritable bowel syndrome – Lancet Gastro “Weekend Effect” in patients with… Continue reading GI Pearls – February 2018 – Episode 17
Show Notes for January 2018 – Episode 16 Does rectal diclofenac reduce post-ERCP pancreatitis? A district generalhospital experience – Frontline Gastro 2017 IDSA Clinical Practice Guidelines for the Diagnosis & Management of Infectious Diarrhea – Clinical Infect Dis Association of Clinician Denial of Patient Requests With Patient Satisfaction – JAMA Int Med No association between… Continue reading GI Pearls – January 2018 – Episode 16
Show Notes for January 2018 – Episode 15 Colonoscopy Surveillance After Colorectal Cancer Resection – JAMA Glucocorticosteroids for people with alcoholic hepatitis. Cochrane Database Syst Rev 2017 Effects of liraglutide on weight, satiation, and gastric functions in obesity: a randomised, placebo-controlled pilot trial – Lancet Gastro Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older… Continue reading GI Pearls – January 2018 – Episode 15
Show Notes for December 2017 – Episode 14 Efficacy of a 4-Food Elimination Diet for Children With Eosinophilic Esophagitis -CGH How to obtain and use chromoendoscopy dyes for surveillance colonoscopy in inflammatory bowel disease: a technical guide – GIE Endoscopy in inflammatory bowel disease: advances in dysplasia detection and management – GIE Endoscopy in inflammatory… Continue reading GI Pearls – December 2017 – Episode 14
Show Notes for November-December 2017 – Episode 13 Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study – GUT Association Between Use of Thiopurines or Tumor Necrosis Factor Antagonists Alone or in Combination and Risk of Lymphoma in Patients With IBD – JAMA Complications of Bariatric Surgery: What You Can… Continue reading GI Pearls – November-December 2017 – Episode 13