Podcasts about adults

Antidepressants are some of the most prescribed drugs in the US, but they may not be getting proper scrutiny. Dr. Sanjay Gupta talks to psychopharmacologist Dr. Joseph Goldberg about what to consider when stopping or starting one. Madeleine Thompson & Sofia Sanchez produced this episode. Video production by Ted Severson and Jilanne Doom with assistance from Jasmine Brooks. Andrea Kane is the medical writer. Dan Dzula is the technical director, and Dan Bloom is the showrunner. Ben Tinker is vice president of news at CNN, and Zach Goldbaum is senior director of podcasts at CNN. Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Nurses Report on America Out Loud with Kimberly Overton, BSN, RN, BC-FMP – Jennifer Rose shares her experiences as an autistic author and advocate, exploring independence, creativity, identity, and grief. Through her writing and plans for Autonomy, she creates space for autistic voices to speak freely. Her conversation with Kimberly Overton challenges assumptions and highlights the importance of listening...

You'd swear you sent that email. You can picture yourself writing it. And then you find it, unsent, still marked unread.This week, Pete and Nikki borrow the literary idea of the unreliable narrator to explore why ADHD makes us shaky witnesses to our own lives. They look at how working memory, time blindness, and mood bend the story we tell ourselves, and at research showing how far self-assessment can drift from the record. Then they turn to practical ways to get a clearer picture: asking the people around you what they see (RSD and all), capturing moments while they're fresh, and letting the data you already generate tell you what you actually accomplished. Along the way, Nikki shares how coaching helps clients notice their own patterns, and why a log should help you see instead of grading you.Links & NotesAccuracy of Self-Evaluation in Adults with ADHD: Evidence from a Driving Study, the 2005 Knouse, Bagwell, Barkley, and Murphy study Pete discussesThe Fragile Dance of Memory and ADHD with Dr. Daniella Karidi, one of the three episodes referencedADHDtime, Daniella Karidi's coaching practiceJoin our Patreon communityJoin the Discord (00:00) - Welcome to Taking Control: The ADHD Podcast (01:43) - Patreon! (03:14) - The Unreliable Narrator (11:21) - Moods (21:33) - "Just Notice" (27:11) - Feedback and RSD (36:23) - Feedback and Grading ★ Support this podcast on Patreon ★

In the first part of this two-part series, Dr. Tesha Monteith and Dr. Tamara Pringsheim provide a brief overview of the guideline recommendations for pharmacologic treatment of migraine prevention in adults.  Show citation:  Potrebic S, Tanveer S, Becker WJ, et al. Pharmacologic Treatment for Migraine Prevention in Adults Practice Guideline Recommendations: Report of the AAN Guidelines Subcommittee and the American Headache Society. Headache. Published online August 31, 2026. doi:10.1111/head.70199 

Do adults who aren't romantic with each other ride roller coasters together? Raye and Michael B. Jordan claim they can and we disagree. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

With Stefan Simovic, Faculty of Medical Sciences, University of Kragujevac, Kragujevac - Serbia, Georgia Sarquella Brugada, Hospital Sant Joan de Deu, Barcelona - Spain and Giulio Conte, Cardiocentro Ticino Institute, Lugano - Switzerland. In this podcast, Georgia Sarquella and Giulio Conte discuss the EHRA Clinical Consensus Statement on ultra-rare inherited arrhythmia syndromes, exploring the challenges of diagnosis, genetics, foetal electrophysiology, and lifelong management from childhood to adulthood.

Love Thy Neighbor: Episode Notes Episode: "The Dinner Divorce" (LTN48) Hosts: Tom Vann, Colette Fehr, Dan Dennis | Guest: None Sponsors / Ad Reads No sponsor segments or ad reads in this episode. Segment Rundown Cold open: intro debate. The hosts argue over whether they need to introduce themselves at the top of every show. Tom calls it pointless since listeners already know who they are. They float making a new intro with names in it for year two, to mark the show's anniversary. What's a food divorce? Colette talks about her recent news appearance on "food divorce," which is when couples eat separately and each person handles their own meals. She puts it alongside other trends like sleep divorce. Dan asks why those couples even live together. The Dennis family dinner. Dan says he and Andrea sit down to dinner together every night, while Maisie often eats at dance. He calls the ritual almost as important as sex because it's when Andrea opens up, including her project manager work gossip. He also covers meal kits like Home Chef and Blue Apron and his weekly meal prep for Maisie. Colette on connection rituals. Colette explains that shared meals are one of the few unstructured connection rituals couples have left. People who grew up eating as a family tend to keep doing it. She shares how she ate alone in her room as a teenager after her parents divorced, making prank conference calls. Tom at the head of the table. Tom's family eats together too, and he likes sitting at the head of the table. He jokes that nobody should introduce themselves there either. He complains that his kids share nothing, eat slowly, and ignore his celebrity stories (he recently talked to the actor who played Puddy on Seinfeld). Colette suggests word games to liven things up, and Tom says his car-ride games haven't gone well. Dan's date nights. Dan says he's recently enjoyed date nights at a local tavern known for crispy pizza, where he mostly just listens to Andrea talk. Quiet Kobe. Tom's wife took their youngest son Max to Hamilton at Dr. Phillips, so Tom took his oldest son Tommy to Kobe Japanese Steakhouse. The two barely talked all night, then Tommy turned on the TV as soon as they got home. Lots of jokes about the oil, the "double white" rice, and the aftermath. Tom also recalls quiet car rides with the men in his family, including a story that started with "one time I killed a man." Companionable silence. Colette reframes the Kobe night: small talk isn't necessarily more connecting than silence, and parents shouldn't feel guilty about quiet moments. Dan and Andrea both thought the outing was great. Dan mentions upcoming one-on-one time with Maisie while Andrea travels for work. In defense of food divorce. Colette says her household basically has a food divorce because of schedules. She wants quiet after a day of doing therapy, and she and her husband still share meals a few times a week. She also points to GLP-1 use and the mental load of meal planning, often carried by women. Her takeaway: do what works, but make time to be present. "What's for dinner?" prank. A host describes his favorite prank: asking his wife what's for dinner at her most stressed moment. It works every time. Email: friend in a scam. "Baltimore Beef Stew" writes about a friend putting $50,000 into an MLM-style unclaimed property scheme despite being warned. Colette says he's already said his piece. Adults have to make their own choices, and he can set limits on what he'll do if it goes badly. Florida Treasure Hunt. The hosts explain that Florida's unclaimed property site, fltreasurehunt.gov, is a real government website even though the name sounds like a scam. They guess the scheme is built around middlemen charging people for money they could claim themselves. When it's your money too. Colette says it's different when a bad decision will land on you financially, like an elderly parent you'd have to support. She shares that she once voiced doubts when her late mother gave money to a questionable religious organization, then let it go. Ask before advising. Tom admits he's a blunt truth teller with the people he loves. His example is laughing off the Grizz's AI-assisted spy novel, and his wife says he comes off like a jerk. Colette's fix is to ask whether someone wants your opinion first. She notes that offhand comments can stick with people for years, and that it's okay to say you're not ready to hear someone's take. Tom's coward approach. Tom says he nods, checks his watch, and then says "that's not going to work" after the person leaves. Also a riff on a past helicopter pilot dream. You don't have a crystal ball. A host says he often stays quiet and then watches things play out just as he predicted. Colette counters that she has seen couples she privately doubted turn things around. She says it's unethical for therapists to tell clients whether to end a relationship, and references Dolly Parton hearing her plans wouldn't work. Joke about the Nigerian prince actually showing up. Email: wife in a hard season. A longtime listener says his 47-year-old wife is moody and down on herself, their kids are about to leave home, one child is struggling, and she has open heart surgery coming up. His compliments aren't landing. Colette says it could be any mix of perimenopause, health stress, empty nest, or feelings about the marriage. She recommends a conversation, possibly a few therapy sessions, and simply being present instead of trying to fix it. Name your own experience. Tom riffs on everything a husband should never say. Colette advises using "I" statements, like saying you feel helpless and worried, instead of telling the other person what's wrong with them. Empathy between genders. Tom says he's glad he never has to go through "the change." Colette lists what women deal with, and Tom agrees men have it pretty easy. Colette warns against letting online anger, tied to a recent news story, turn into hating all men. Perimenopause 101. Colette explains that perimenopause can start in the 30s (a chat room listener said hers began at 39) and that 51 is the average age of menopause. Technically, menopause is a single day, one year after the last period. She shares that she's had few symptoms, and that a past uterine ablation makes it hard to tell where she is. Next week teaser and close. Colette teases a story about a possible perimenopausal outburst that "traumatized" her husband. Chat room member Ryan coined "Quiet Kobe," and Colette jokes her book's paperback will be called The Cost of Kobe. Plugs and sign-off. Key Dates / Plugs Mentioned Recently: Colette appeared on the news talking about food divorce. Recently: Tom's wife and Max saw Hamilton at Dr. Phillips Center through her season subscription. Year two: The show is celebrating its anniversary, which prompted the new intro idea. Upcoming: Andrea's work trip to Austin, Texas, which means one-on-one time for Dan and Maisie. Upcoming holiday (Presidents' Day, per Dan): Dan has a day off to plan an outing with Maisie. Next week: Colette's perimenopause outburst story. Ongoing: Insights from the Couch, the hosts' other podcast. Ongoing: Send emails to hello@lovethyneighborshow.com. Ongoing: fltreasurehunt.gov, Florida's official unclaimed property search. Notable Guests/Callers Baltimore Beef Stew: Listener email (made-up name) about a friend caught in an unclaimed property MLM scheme. Anonymous longtime listener: Email from a husband whose 47-year-old wife is going through a difficult stretch. Ryan (chat room): Coined "Quiet Kobe" / "The Cost of Kobe." Chat room listener: Said her perimenopause started at 39. The Grizz (mentioned, not on air): Friend whose spy novel Tom dismissed.

Adults vuelve con una temporada 2 más divertida, más segura y bastante mejor afinada que la primera. En esta crítica sin spoilers analizamos el regreso de la comedia de FX, su reparto, la química entre Samir, Billie, Paul Baker, Issa y Anton, el humor, las nuevas dinámicas y por qué la serie funciona mucho mejor cuando deja de intentar representar a toda la Generación Z y se concentra en sus personajes. También hablamos de sus puntos débiles, de los cameos de esta temporada y de si Adults puede consolidarse como una de las comedias de amistad más interesantes del momento. Adults Temporada 2 se estrena en Disney+ el 30 de septiembre. #Adults #AdultsSeason2 #DisneyPlus #FX #Series #CriticaSeries #RazonesParaVer Únete a nuestro canal y apoya a FUERA DE SERIES: https://www.youtube.com/channel/UCFNyyACx7XbgZ4-S4jzNnGQ/join Únete a nuestro chat de telegram en el que miles de personas hablamos cada día de series: - Telegram – Grupo de debate: https://telegram.me/fueradeseries - Telegram – Canal de noticias: https://t.me/noticiasfds Síguenos en nuestras plataformas y podcast sobre series: - Apple Podcast - https://podcasts.apple.com/es/podcast/fuera-de-series/id288039262 - Spotify - https://open.spotify.com/show/3RTDss6AAGjSNozVOhDNzX?si=700febbf305144b7&nd=1 - iVoox - https://www.ivoox.com/podcast-fuera-series_sq_f12063_1.html Redes Sociales - Twitter: https://twitter.com/fueradeseries - Facebook: https://facebook.com/fueradeseries - Instagram: https://www.instagram.com/fueradeseries/ - Youtube: https://youtube.com/fueradeseries Learn more about your ad choices. Visit megaphone.fm/adchoices

Join Lil' Lo and Big Shot Shae as they discuss Last Ditch, a lesbian bar in Massachusetts that made masks optional for one night a week and how it showcases how progress can destroy itself if you let it, the new student loan repayment plans and how no one can afford them, Adults on FX becoming one of the greats of new television, Wonka: The Golden Ticket on Netflix being a torture chamber, and more! Email for advice / to be featured: LetMeStayFocused@gmail.com Follow Our Hosts:@lilloworldwide@bigshotshae**DISCLAIMER: THIS IS A COMEDIC PODCAST** Scenarios and responses from this show should be taken with a grain of salt. In other words, this is all a joke. Unless otherwise noted, any similarity to actual persons, living or dead, or actual events, is purely coincidental.Timestamps:13:11 — What We're Watching29:01 — Honorable Mention35:14 — Hotep of the Week43:11 — Lyrics and Lessons50:00 — Let Me Stay Focused68:56 — Advice from the Internet

Schools spend most of their time on academic skills, but the social and emotional skills that carry us through adult life often get left behind. Why don't schools prioritize social-emotional learning (SEL), and what would change if they did?In this episode, we talk with Dr. Lorea Martinez Perez, a former special education teacher, former Columbia University Teachers College faculty member, and creator of the HEART in Mind methodology. She holds a PhD in quality and innovation in education and is the author of Teaching with Heart in Mind.In this episode:Why social-emotional skills matter more in adult life than schools acknowledgeHow Lorea's path shaped her mission, from teaching Spanish to North African immigrant women in Spain as a teen, to interning in Nicaragua, to special education in the Bay AreaWhat it was like to learn a faster-paced U.S. school system and English alongside her studentsHow the Heart in Mind method brings social-emotional learning into the classroomConnect with Dr. Lorea Martinez PerezWebsite: loreamartinez.comYouTube: Heart in MindLinkedIn: Lorea MartinezInstagram: @‌drloreamartinezFacebook: Lorea Martinez SELWork with MaxadyReady for your next step? Maxady helps you find the role that fits your skills, your life, and your squiggle.Connect with your hostsColleen DelVecchio: LinkedInAshleigh Beadle: LinkedInSubscribe and reviewKnow someone who'd love this episode? Share it with them. If you haven't left a review yet, it helps more people find the show

Can the people around us influence how well we eat? In this episode, Douglas Taren speaks with lead author Halimatou Alaofè to discuss how support from family, friends, and peers may help people with Type 2 Diabetes make and maintain healthier dietary choices.

Characteristics and epidemiology of children and adults with cerebral palsy in Latin America.

业余时间 spare time事儿教人 learning by doing实际经验 Practical experience面对面 face to face

业余时间 spare time 事儿教人 learning by doing 实际经验 Practical experience 面对面 face to face

This week's Managed Care Cast episode features a conversation between The American Journal of Managed Care® (AJMC®) and Grace Mackleby, PhD, a research scientist at the USC Schaeffer Center, about her study, "Plan Switching Among Medicare Advantage Enrollees Dually Eligible for Medicaid," published in the September 2026 issue of AJMC. The study examined how often beneficiaries switched from one Medicare Advantage (MA) plan to another or from MA to traditional Medicare (TM). It compared enrollees dually eligible for Medicaid with those eligible for Medicare only. Mackleby explained that dually eligible beneficiaries account for about one-fifth of the Medicare population and tend to have more chronic conditions, higher costs, and greater needs; they are also subject to different rules on when they can switch plans. Mackleby and coauthors Angela Liu, PhD, and Erin Trish, PhD, used administrative Medicare enrollment data to track switching from 2016 to 2022. She highlighted 3 main results. First, about 22% of fully dually eligible enrollees switched MA plans in 2022, up from about 12% in 2016. Second, these enrollees were roughly 6 times more likely to switch to another MA plan than TM. Third, dually eligible beneficiaries overall switched MA plans more often than those eligible for Medicare only. The study did not examine causes, but Mackleby pointed to 2 likely drivers: the growing number of available MA plans and the strong competition among insurers, which have heavily marketed supplemental benefits such as flex cards and dental coverage. For non–dually eligible beneficiaries, she added, it is difficult in most states to obtain Medigap coverage after enrolling in MA, which makes returning to TM financially unappealing. Switching also varied by race and ethnicity. Black, Hispanic, and American Indian/Alaska Native fully dually eligible enrollees switched MA plans more often than non-Hispanic White enrollees. Mackleby said geography may play a role. However, higher switching could also indicate lower satisfaction with available plans, which warrants further study, she noted. Looking ahead, Mackleby emphasized the need to understand whether switching helps or harms beneficiaries, including its effects on access to care and cost sharing. She also called for research on how switching shapes market performance. "I think looking at it from a beneficiary welfare perspective is going to be really important, and then also looking at it from a market perspective is going to be important too," Mackleby concluded.

Asst Prof Eric Chin: Interference pain in adults with CPAs an award finalist for 3 different categories (Promising Career Award Finalist; Southern Family Cerebral Palsy Center Best Adult Paper Award Finalist; Complex Care Early Career Award Finalist), this work is clearly important for the field.Dr Chin joins us to discuss his paper titled "Multidimensional Impacts of Chronic Pain and Associated Risk Factors in Self- reporting Adults with Cerebral Palsy: A Community Registry Study."It is fantastic to see the work that is being done now in adults with CP.

I just had a close friend over and the next time we were both available to hang out was in 2 MONTHS. Then I watch these TV shows, like Friends, New Girl, Adults, and How I Met Your Mother, where they're all hanging out with each other all the time. So I asked myself: can real life friendships be as good as the friendships portrayed on TV? I dove into these sitcoms and the science, and it turns out there are five very real steps we can all take to have sitcom-level friendships in our real adult lives (no matter where we live or how old we are). I came up with this action plan for a sitcom friend fall. Sitcom friend fall is a commitment we're all taking together to have truly fun, fulfilling, and deeper friendships in our lives this fall.

Dr. Tesha Monteith talks with Dr. Tamara Pringsheim about the updated American Academy of Neurology (AAN) and American Headache Society (AHS) guidelines on pharmacologic treatment for migraine prevention in adults.  Read the related article in Neurology®. Disclosures can be found at Neurology.org.  Show transcript:  Dr. Jose Merino (00:08): This is Jose Merino, editor-in-chief of the Neurology Family of Journals. The Neurology Podcast provides practical information to neurologists and other clinicians to help them provide better care for their patients. Thanks for listening and have a great week. Dr. Tesha Monteith (00:23): Hi, this is Tesha Monteith with the Neurology Podcast. I'm excited to talk to you today about the update in Migraine Guideline: Pharmacologic Treatment for Migraine Prevention in Adults: Practice Guideline Recommendations, a report of the American Academy Neurology Guidelines Subcommittee, and the American Headache Society. Since the last guideline in 2012, there's been a lot of new advances, including the introduction of CGRP inhibitors for acute and preventive treatment. (00:53): With me to discuss is the lead author, Tamara Pringsheim, a neurologist at the Department of Clinical Neurosciences, Psychiatry, Pediatrics, and Community Health Sciences at the University of Calgary. How are you, Tamara? Dr. Tamara Pringsheim (01:06): Great. Thank you for asking me to talk to you about this. Dr. Tesha Monteith (01:09): Why don't you tell me a little bit about yourself and how you got involved in this work? Dr. Tamara Pringsheim (01:14): Sure. I've been working as a methodologist for the American Academy of Neurology Guidelines Subcommittee for a number of years, since 2015. Prior to that, I was a member of the guideline development subcommittee from 2011. I've worked on a number of different guidelines across neurological conditions. Dr. Tesha Monteith (01:36): Great. So how do these new guidelines compare, just broadly speaking, with the older guidelines? Dr. Tamara Pringsheim (01:43): I guess since the last guidelines were published more than 10 years ago, we've had changes to our methodological process. We had a major update to our guideline process manual in 2017, and guideline methodology has continued to evolve over that time period. And as well, a number of targeted treatments for migraine have come out. So there's been an explosion of evidence, particularly in the last five to seven years. And so we have a whole new class of medications available for migraine prevention, which really target our underlying understanding of the condition, whereas most of the other medications were discovered through serendipity. Dr. Tesha Monteith (02:33): So I know that you reviewed over 200 randomized controlled trials. And so how was the quality or confidence of the evidence determined? Dr. Tamara Pringsheim (02:47): With our process, we start by rating risk of bias for every article. This basically gets at a number of different features related to the clinical trial methodology and reporting, and it helps us determine how confident we are in the evidence. In order for us to be highly confident that the results that we are seeing reflect the truth, we typically need to have at least two Class 1 studies for any intervention outcome pair. The effect size estimate also has to meet a certain threshold in terms of the effect size and the precision surrounding that estimate. So if we feel that based on what the panel decides in terms of what is the minimal clinically important difference between an intervention and placebo, that will help us determine our confidence in the evidence. (03:51): So there's this critical coming together of the number of studies, the quality of studies, the effect size, and the precision of the evidence that helps us determine our confidence in the evidence. And all of this is done behind the scenes using a very algorithmic approach so that these rules are faithfully applied across the different interventions we're looking at. This complexity makes it hard for people to understand why certain drugs land in a certain area, but it's one of the things that we do to make this process standardized and rigorous. Dr. Tesha Monteith (04:37): So I do want to talk to you about that, where drugs have landed. One newer thing was that the review was not just episodic migraine, but also chronic migraine. Dr. Tamara Pringsheim (04:47): Yes. Dr. Tesha Monteith (04:48): Were there important differences in the strength of evidence between these populations? Dr. Tamara Pringsheim (04:53): One thing that's really important to remember is that the use of the term chronic migraine is fairly new. So a lot of the trials of the older headache preventive medications were done in the 80s and the 90s. And at this time, there wasn't a definition which distinguished chronic migraine in particular. So a lot of the trials for amitriptyline, for example, were not done in a purely episodic or chronic migraine population. And so this really contrasts with the newer studies where these populations were well-defined. And so we're going to have higher quality evidence or evidence specifically for chronic migraine with the new drugs, whereas for the old drugs, we won't have that. Dr. Tesha Monteith (05:50): Let's get into the preventive treatments that had the strongest level of evidence for episodic migraine. Dr. Tamara Pringsheim (05:57): We had high confidence in the evidence for two of the CGRP medications, erenumab and galcanezumab. Again, these high confidence in the evidence statements are based on the fact that for both these drugs, there were multiple Class 1 studies showing that they were efficacious. And the effect size was in the range that was pre-specified. So the lower level of the 95% confidence interval was clearly higher than what we decided was the minimal clinically important difference. Both these drugs, one had two Class 1 studies, one had three Class 1 studies, so we could be very highly confident that these two medications were efficacious. (06:50): Now for the moderate confidence drugs, we have a longer list for episodic migraines. So it includes atogepant, eptinezumab, fremanezumab, propranolol, rimegepant, topiramate, and valproate, and then a slightly longer list for the low confidence drugs. So amitriptyline, bisoprolol, flunarizine, fluoxetine, levetiracetam, metoprolol, nifedipine, pizotifen, and telmisartan. (07:18): And for this outcome, I'm specifically talking about episodic migraine headache days. Now, one of the layers of complexity, again for this guideline, is that we had a few different outcomes that we were looking at. So the two main outcomes we were looking at were the headache frequency, the change in the number of headache days, but also the 50% responder rate. That's the proportion of people in the treatment group who had at least a 50% reduction in their headache frequency. And some drugs would make it for one endpoint, but not the other. And this is an important nuance that, again, adds complexity to our data synthesis. Dr. Tesha Monteith (08:06): And what about for chronic migraine? Dr. Tamara Pringsheim (08:08): So for chronic migraine, for the number of headache days, we had high confidence for fremanezumab, galcanezumab and onabotulinumtoxinA, and moderate confidence for atogepant, eptinezumab, erenumab, topiramate, rimegepant, and valproate. We didn't have any medications that were in the low confidence in the evidence category. Dr. Tesha Monteith (08:33): Oftentimes in the newer clinical trials, we're looking at change in monthly migraine days, but interesting that you looked at headache days. Dr. Tamara Pringsheim (08:42): Yeah. So another difficulty is that there's not always consistency in what's reported. So some trials would report headache days and some trials would report migraine days per month. Wherever possible, we use the change in the number of days with migraine. And where this was not present, we would use headache days. Dr. Tesha Monteith (09:08): Now, a drug that we use very often in clinical practice is rimegepant, which has a dual benefit of acute attack treatment as well as prevention. And that was rated as low confidence, but in a recent International Headache Society, Italian guidelines, that was noted as moderate quality evidence, strongly in favor of. What do you think that discrepancy was about? Is that a matter of outcomes or? Dr. Tamara Pringsheim (09:38): This guideline includes clinical trials that were published up until June of 2024. And so at that time, the only trial of rimegepant versus placebo that was published was in a population of patients that had episodic or chronic migraine. The population was combined. And so we only have one study. And as I was explaining at the beginning, in order for us to have high confidence in the evidence, we have to have at least two Class 1 studies and the minimal clinically important difference has to meet a certain threshold. So for rimegepant in June of 2024, there's only one study published versus placebo. So the highest possible confidence in the evidence we could have for rimegepant based on the fact that just one study would be moderate. (10:38): The reason why it's not listed in recommendation 3A as high or moderate confidence is because while we had moderate confidence in the evidence for rimegepant on the number of headache days, we had low confidence in the evidence for the 50% responder rate. And that's because for the 50% responder rate, it did not meet the pre-specified cutoff with respect to the minimally clinically important difference. (11:11): So again, it's a small nuance in the evidence, but for an evidence-based guideline, we really pay attention to these things. I know it makes it complex and hard for people who are not immersed in the evidence to understand. This is part of the rigor. There's a temptation to oversimplify things so that it's easy to understand, but that's really one of the strengths of the AAN process is that we take the evidence very seriously. We are truly evidence-based. We are going through every data point very carefully, and so that you should feel confident when you see that we've rated these medications as a higher moderate confidence, that we've really looked and evaluated these data points very carefully. Dr. Tesha Monteith (12:01): We can say that different guidelines have different outcomes. And to your point, it's more than just the data. It's your pre-specified process that then led to those recommendations, right? Dr. Tamara Pringsheim (12:14): Yeah. And I feel pretty confident that if we were to update the evidence, including the last two years, that rimegepant would move up, right? Because just looking even quickly now, we can see that since 2024, there have been several additional studies published. So now we wouldn't just be basing our evidence review on one placebo controlled study. There have been several more, the medications FDA approved. Dr. Tesha Monteith (12:44): Right. Dr. Tamara Pringsheim (12:45): I don't think anyone should change their practice based on this and people should be using rimegepant. That's not the message that we're trying to send. Dr. Tesha Monteith (12:54): That's really important. Dr. Tamara Pringsheim (12:55): Yes. We are not on a campaign to say that rimegepant is not a treatment option. As you can see, it is listed and it is in the guidelines. It's just based on the data we had available, we had low confidence in one of the outcomes, the 50% responder rate. So I hope that makes sense. Dr. Tesha Monteith (13:14): Yeah, I think it makes sense. It's the processes, it's a 2017 guideline manual, and that does make sense. So thank you for that clarification because a lot of our clinicians will be asking questions about this. Dr. Tamara Pringsheim (13:26): I mean, the same goes for another drug, candesartan is the other one. Dr. Tesha Monteith (13:30): Yeah. Candesartan recently had a paper published in the Lancet. Dr. Tamara Pringsheim (13:33): Yes. Dr. Tesha Monteith (13:33): And it did well, and people are using candesartan. Dr. Tamara Pringsheim (13:38): Yes. Yes, exactly. I prescribe candesartan for migraine prevention. At the time we did the evidence review, we had a couple of positive studies, a couple of negative studies. And when we put the data together, it came out as very low confidence because there's a discrepancy. And then we have a huge trial published that is a positive study, but it came out in 2026. It was not part of our evidence review. We don't say anywhere in the guideline, don't use candesartan, right? We don't say that. We highlight the drugs for which we have the confidence in the evidence and put them in there. But we need to remember that new drugs are coming out all the time and that they didn't factor into our decision making. (14:26): So again, I hope that people don't read the guideline and say, "Oh my God, I can't use candesartan." That's not true. Dr. Tesha Monteith (14:33): So one thing I want to look at is quality of life outcomes. That was something also not seen in the first or the 2012 guidelines. And so how did you look at quality of life outcomes and how should we consider them? Dr. Tamara Pringsheim (14:47): Yeah, so we wanted to make sure that we incorporated patient reported quality of life outcomes in the guideline, recognizing that this is very important. And the newer trials of the more recent medications have been incorporating patient reported quality of life outcomes in their clinical trials. This adds overall credibility that we are incorporating into our decision-making evidence that not only are patients' number of headache days decreasing, but their quality of life is improving because that's important to patients and hence is important to us. (15:31): So we used outcomes from validated measures of migraine related quality of life. So there's the MIDAS, there's the HIT-6, and there's something called the migraine specific questionnaire, which has three subscales. One is emotional function, one is role function preventive, and one is role function restriction. And then a few studies use something called the migraine physical function impact diary. So those were the main instruments that we looked at. And again, we had a pre-specified minimally clinically important difference on these instruments that we looked at. (16:19): And we had a reasonable amount of data, not as much data as we had for headache days or the responder rate, but certainly again, for the CGRP antagonists, we had high confidence in the evidence for galcanezumab, for example, in episodic migraine. And for chronic migraine, we had moderate confidence in the evidence for a number of medications including topiramate and onabotulinumtoxinA. So these quality of life measurements seem to be increasingly used in our modern clinical trial era. Dr. Tesha Monteith (17:07): Great. Another question is just thinking about some of the limitations of this work. There were very few high quality head-to-head trials. How does that limit your comparative effectiveness data? Dr. Tamara Pringsheim (17:19): This is a major issue that most, but not all of the head-to-head trials were investigator-led. Many were done a very long time ago before the modern clinical trial era, and so the quality of these studies was low. And also they were not non-inferiority studies. So basically the only question they could answer is whether drug A is better than drug B based on their trial protocol and methodology. And for most of the comparisons, we have very low quality evidence, so we really cannot support or refute that drug A is better or worse than drug B. So we can't really say anything. There were a few instances where we could say that drug A is better than drug B, but it's low confidence evidence, very few comparisons. (18:17): Some evidence is emerging so that some of the CGRP drugs are being compared to some of the older drugs now with the hope that we can prescribe these sooner to migraine patients. That evidence will probably emerge in the coming years. Dr. Tesha Monteith (18:31): And another question is how should these guidelines be incorporated in clinical practice also while balancing tolerability, comorbidities, patient preference, reproductive considerations, access, and costs? Dr. Tamara Pringsheim (18:47): So we have the evidence synthesis. So you can say, okay, this is the evidence. These are the effect sizes. This is the number of studies to support this outcome, that outcomes. You have the details in the systematic review, right? And then how do you take those details and apply them in the practice? And that's the art of medicine. And we don't make decisions without our patients. All of our decisions are collaborative. I say to my patients, "It's my job to tell you what your options are. It's your job to discuss these options with me and for us to make a decision together regarding which one is the best for you in your situation." (19:30): And that's what we're trying to do in the recommendations. In the recommendation statements, you'll see that in this specific situation, this might be a better choice. We talk a lot about when you're going to decide to even start a preventive and the importance of shared decision making, that those are our first two sets of recommendations. Recommendations one and two are about those things. (19:56): And then our recommendation three statements just tries to gently offer some advice on when you should think about which medication, where efficacy is the priority, tolerability is the priority, long-term harms, cost. Cost is a really tricky one because cost really depends on the person's specific pharmaceutical formulary plan and healthcare insurance. I know that for some patients, their insurance plans require a certain number of oral medications to be tried before an injectable like a botulinum toxin or a subcutaneous medication or one of the newer medications can be prescribed. Dr. Tesha Monteith (20:41): So you put a lot of work in this, your team, the American Academy of Neurology, the American Headache Society, outstanding work. What should we take away from this? Dr. Tamara Pringsheim (20:52): I think that we should take away that a lot of work is being done by headache neurologists and neuroscientists who are interested in headache to develop new treatments for people with migraine. I think that the CGRP drugs are a major advance and that now we have many new medications that are specifically designed for migraine treatment and these treatments are changing people's lives for the better. I think it's brought new hope to people with migraine and it's an exciting time to be a clinician who treats patients with migraine when you have several new medications where the companies have invested the time to do the research, do well-designed clinical studies, and that we can feel confident that these medications are helping our patients. Dr. Tesha Monteith (21:51): Excellent. I couldn't have said that better. Thank you again for your work and your time and for being on our podcast. Dr. Stacey Clardy (22:00): This is Stacey Clardy, your podcast editor. If you've enjoyed the podcast, please take a few moments to subscribe, rate, and review the Neurology Podcast through Apple Podcasts, Google Podcasts, Spotify, or wherever you listen. And remember, you can always head to neurology.org/podcast for our full list of past episodes, or you can also search by keyword on the podcast app for any neurology specific topics.  

(September 28, 2026) Neil Saavedra fills in for Bill while he is in Africa on a safari vacation. Owning a home is seen as a financial holy grail but what if it isn’t. The 20-something employees who want feedback to be gentle. Why are so many adults cutting off their parents? Stanford apologizes, saying AI altered photo that changed students gender and race violated policy.See omnystudio.com/listener for privacy information.

Send us Fan Mail What if the colleague you've been describing as "quirky" is the most underused talent in your building? In this episode of Coaching the Whole Educator, Becca Silver sits down with Justin Permenter of NDI Institute to talk about building workplaces where neurodivergent educators, coaches, and leaders can perform, contribute, and lead without lowering expectations. Roughly one in five people is neurodivergent, including people with ADHD, autism, dyslexia, and dyspraxia. Yet most schools and organizations are built for neurotypical ways of working by default. Students get IEPs and 504 plans. Adults get a workplace that expects everyone to sit at the same table, the same way, on the same timeline. Justin shares his journey from the classroom in Kansas City to international education in Qatar and his work with Franklin Covey's Leader in Me, plus the story of Omar, a 16-year-old autistic intern who outperformed full-time staff at the Waldorf Astoria within three weeks. Becca opens up about her own ADHD diagnosis and the moment she started seeing it as a strength instead of a deficit. You'll learn: Why accommodation and compliance checklists aren't the same as strengths activationHow curiosity (the C in NDI's CLEAR framework) replaces judgment when a colleague works differentlyWhat "results alignment" means: keeping outcomes high while allowing multiple pathways to get thereOne thing school leaders and instructional coaches can do tomorrow to lead more neuroinclusivelyPerfect for instructional coaches, principals, district leaders, and anyone who leads adults in schools. Resources mentioned:Website: www.ndiinstitute.comWebinar on October 6th: https://www.ndiinstitute.com/webinarFree C.L.E.A.R. Framework: https://www.ndiinstitute.com/download The Resistance Solution: Why Educators Resist and What They Need Instead: amzn.to/4pRCaa5Resistance Solution Book Study Facilitator Training: https://www.thewholeeducator.com/book-study-facilitator-training Let's Stay Connected!Website  |  Instagram |  Twitter |  Linkedin |  Facebook |  Contact Us

In This Episode Erin and Weer'd discuss: a rabbi suing Maryland for violating his 1st, 2nd, and 14th Amendment rights; the DOJ in a showdown with Wisconsin over their purchase permit system; the DOJ suspending prosecution on pistol buyers 18-20 years old; the gun prohibitionists butthurt that Trump is relaxing restrictions on NFA items; Glock suing Connecticut for banning Glocks; and the Philippines want to search the homes of gun owners to verity their compliance with firearm storage laws. Xander gives us his Independent Thoughts on surviving a convention; and David gives us his 223rd segment to talk about the .223 Remington cartridge. Did you know that we have a Patreon? Join now for the low, low cost of $4/month (that's $1/podcast) and you'll get to listen to our podcast on Friday instead of Mondays, as well as patron-only content like mag dump episodes, our hilarious blooper reels and film tracks. Main Topic Synagogue Scores Early Win Against Maryland County's Gun Restrictions DOJ Gives Minnesota Until Sept. 23 to Negotiate or Face a Federal Suit Over 30-Day Handgun Purchase Waits That Stretch to Nearly 60 Handgun Sales to Adults 18 to 20 Are Constitutional, Says Trump DOJ Trump Tells DOJ to Back Off Case Making Getting the Worst Guns Easier GLOCK Sues Connecticut Over Its "Vague, Ambiguous and Unclear" Convertible Pistol Ban Law Philippine Government Wants to Inspect Gun Owners' Homes Independent Thoughts Walker's Shooting Training Protection 29 DB Omni-Directional Microphone Rope Hearing Enhancer Earbuds Walker's Lightweight Rechargeable Shooting Hunting Razor XV 3.0 Gun Lovers and other Strangers SCHV .222 Remington .222 Remington Magnum .223 Remington 5.56×45mm NATO .223 Wylde Chamber General Curtis LeMay Remington Model 760 Gamemaster SAAMI Again and Again Brena Bock Author Page David Bock Author Page Team And More  

Pediatric transplant champions Melissa McQueen and Jennifer Lau share their experiences as transplant recipient caregivers and weigh in on needed improvements to the national system.Important Links: BARE: www.bareinc.orgTransplant Families: www.transplantfamilies.orgChildren's Organ Transplant Association (COTA): www.cota.org#PediatricTransplant #TransplantFamilies #OrganTransplant #TransplantJourney #CoffeeAndCompatibility

Dr Cristina Sarmiento: The Lived Experience of Primary and Preventive Care for Adults with Cerebral PalsyGayle G. Arnold Award Finalist; Promising Career Award Finalist; Southern Family Cerebral Palsy Center Best Adult Paper Award FinalistRecorded LIVE at AACPDM 2026 Philadelphia

Relebogile Mabotja speaks to Kelly du Plessis the CEO of Rare Diseases South Africa and Sara Norcross the General Manager of Novo Nordisk South Africa about Growth Hormone Deficiency, or GHD, which can affect adults too. And unlike in children, where delayed growth may be a more obvious sign, the symptoms in adults can be much harder to recognise. 702 Afternoons with Relebogile Mabotja is broadcast live on Johannesburg based talk radio station 702 every weekday afternoon. Relebogile brings a lighter touch to some of the issues of the day as well as a mix of lifestyle topics and a peak into the worlds of entertainment and leisure. Thank you for listening to a 702 Afternoons with Relebogile Mabotja podcast. Listen live on Primedia+ weekdays from 13:00 to 15:00 (SA Time) to Afternoons with Relebogile Mabotja broadcast on 702 https://buff.ly/gk3y0Kj For more from the show go to https://buff.ly/2qKsEfu or find all the catch-up podcasts here https://buff.ly/DTykncj Subscribe to the 702 Daily and Weekly Newsletters https://buff.ly/v5mfetc Follow us on social media: 702 on Facebook https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/Radio702 702 on YouTube: https://www.youtube.com/@radio702 See omnystudio.com/listener for privacy information.

Kun bangers i denne episode! Frederik og Kasper har endelig fået set Obsession, som nu kan streames. Uden at afsløre for meget kan vi godt konstatere, at de er pænt obsessed – men lever filmen op til den sindssyge hype? Og er hovedpersonen ond eller et offer? Kasper har også set anden sæson af komedieserien Adults, som han mener fortjener langt mere opmærksomhed. Frederik har set femte og sidste sæson af The Bear, som tager sig lidt anderledes ud her på falderebet. Alt i alt: gode anbefalinger - helt uden spoilers! 00.00: Obsession 21.40: Adults S2 27.53: The Bear S3 Følg Frederik og Kasper her: https://www.playpilot.com/dk/user/streamteam https://www.instagram.com/frederikdirks  https://www.facebook.com/streamteamradio/  https://www.instagram.com/kasperlund  

Read OnlineEmbracing and Becoming the LeastAn argument arose among the disciples about which of them was the greatest. Jesus realized the intention of their hearts and took a child and placed it by his side and said to them, “Whoever receives this child in my name receives me, and whoever receives me receives the one who sent me. For the one who is least among all of you is the one who is the greatest.” Luke 9:46–48The Twelve Apostles had left everything behind to follow Jesus. Their lives had been radically transformed. As they accompanied Him on His mission, they heard the very voice of God preach and teach. They witnessed His divine power as He performed miracles and cast out demons. And yet, today's Gospel reveals that they still struggled with a common weakness of fallen human nature: ambition. They argued among themselves about who was the greatest.Jesus, though surely sorrowful over their foolish dispute, responded not with rebuke but with merciful instruction. He addressed the intention of their hearts by offering a striking lesson as He placed a child at His side. That child became a living parable—a model of true greatness in the eyes of God.In many cultures today, children are cherished, protected, and seen as possessing great dignity. Parents work hard to ensure their children know their value. But in first-century Israel, the perception of children was quite different. While loved by their families, children were socially insignificant. Their high mortality rate and inability to contribute to the household's livelihood often rendered them overlooked or dismissed. For Jesus to place a child at the center of His teaching and to equate receiving that child with receiving Himself would have been both startling and countercultural.In this act, Jesus uproots worldly standards of greatness. In His Kingdom, true greatness is not found in status, success, or acclaim. It is found in humility, simplicity, and openness of heart. To welcome the lowly, the unnoticed, and the vulnerable in Jesus' name is to welcome Jesus Himself. And to welcome Jesus is to welcome the Father who sent Him.Consider whom you most readily welcome and embrace. Teenagers often dream of meeting the rich and famous. Adults may strive for social status or recognition. In truth, we are not so different from the Apostles, who desired esteem among their peers and to be chosen while others are set aside.Jesus offers us two essential lessons through this living parable. First, like our Lord, we must love and embrace the lowly and the weak. Jesus was not drawn to the status of the Pharisees or the social elites. He found joy in embracing the child, the sinner, the tax collector, the leper, the crippled, the blind, and the poor. These were the ones who, because of their low status, were often more humble and receptive. If we wish to be like our Lord, we must seek out the humble and the lowly, for it was to such souls that He was drawn.Second, we are not only called to embrace the lowly, we are called to become the lowly. We must become like children: dependent, vulnerable, humble, and easily overlooked in the eyes of the world. Why? Because those are the very ones Jesus embraced. And if we desire to rest in His arms, we must take the lowest place, trusting that it is there that true greatness is found.Reflect today on the countercultural lesson Jesus taught and apply it to your own life. Turn your eyes to the weakest, humblest, and most vulnerable. Allow grace to draw you to these simple souls. Run to the sinner and outcast. Then, don't stop there. Strive also to live in that same humility and dependence. Turn from worldly views of greatness and embrace Jesus' view. Become like a child, embrace the weakest among you, and our Lord will embrace you. Most loving Lord, though You loved all people with the perfection of charity, Your mercy and compassion poured forth, especially upon the weakest, most humble, and lowliest. Please fill my heart with that same love You so perfectly exemplified. Help me also to heed Your warning that I must become humble and lowly like a child in order to receive the greatness of Your eternal embrace. Jesus, I trust in You.  Source: Free RSS feed from catholic-daily-reflections.com — Copyright © 2026 My Catholic Life! Inc. All rights reserved. This content is provided solely for personal, non-commercial use. Redistribution, republication, or commercial use — including use within apps with advertising — is strictly prohibited without written permission.

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Welcome to the Torg Stories Podcast. We're recording Sunday, September 27, 2026. Topics for this episode include Izzy's first day of shooting on her short film, AI Models that scheme, the Hulu show Adults, Apple's The Gorge, an SNL report, and Anne finished her history of Gold book. It's also a big NFL today and … Continue reading "Short Film Production, Scheming Artificial Intelligence, and The Secret History of Gold"

In his weekly clinical update, Daniel Griffin and Vincent Racaniello frustration continues over the increasing number of measles infections, Kennedy's undermining of vaccines, perpetuation of autism- vaccine, autism-tylenol myths, an outbreak of hepatitis A virus in the US, the Ebola outbreak in Uganda, changes in reporting of virus infection and vaccine recommendations, Legionnaires disease and screw worm cases, and before Dr. Griffin deep dives into recent statistics RSV, influenza, SARS-CoV-2 infections, economics of a measles outbreak in Chicago, what defines reactogenicity of the mRNA COVID vaccines, the on-going delay by HHS of COVID shots for children, neuropsychiatric symptoms of long COVID and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode CDC adds 177 cases to US measles total but has yet to confirm deaths in Pennsylvania (CIDRAP) Kennedy questions vaccine safety at Children's Health Defense event (CIDRAP) Trump says some routine immunizations will be split into five separate shots. Vaccine experts say it won't work (CNN) Multistate Hepatitis A Outbreak Potentially Linked to Frozen Clams (CDC: Hepatitis A) Cumulative Incidence and Prevalence of Autism Spectrum Disorder (JAMA Pediatrics) Data and Statistics on Autism Spectrum Disorder (CDC: Autism Spectrum Disorder) Study uncovers no evidence of autism epidemic, despite claims (CIDRAP) Florida confirms a death from dengue as the state struggles with one of its worst recent outbreaks (AP News) Legionnaires' Disease (NYC: Health) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Democratic Republic of Congo (AP News) Ebola virus (AP News) Congo begins Ebola vaccinations for health workers in the epicenter of the outbreak (AP News) Ebola dashboard (ebola.fyi) EBOLA: The Democratic Republic of the Congo, 2026 (WHO) Bundibugyo virus disease outbreak Democratic Republic of the Congo(WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services) Utah Measles Dashboard (Utah Department of Health and Human Services) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) HAP's Latest News Pa. Launches New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania) Measles (Commonwealth of Pennsylvania) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Pennsylvania asks CDC for emergency assistance amid RFK Jr. clash over measles(The Hill) Pennsylvania measles-associated deaths climb to four as outbreak grows (Reuters) Pennsylvania asks for CDC measles help amid Kennedy dispute (Reuters) Republican senator faults Trump vaccine policy for US measles deaths as panel weighs health nominees (Reuters) US CDC works on standard definition for measles deaths as cases rise (Reuters) Cost of a Measles Outbreak in an Urban Shelter (JAMA Open Network) Measles outbreak in Chicago shelter cost nearly $9 million, CDC estimates (CIDRAP) World's most contagious virus hits major US airport as officials warn of possible exposure (FoxNews) Measles Cases and Outbreaks (CDC: Rubeola) Laboratory Testing for Measles (CDC: Measles (Rubeola) Measles Clinical Diagnosis Fact Sheet (CDC: Measles (Rubeola) Measles Serology Testing (CDC: Measles (Rubeola) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots(CIDRAP) Weekly surveillance report: cliff notes (CDC FluView) OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) Immunogenicity and safety of an MF59-adjuvanted cell-derived higher-dose quadrivalent influenza vaccine (aQIVc) in adults aged 50 years or older: a phase 3 randomised controlled trial (LANCET: Infectious Diseases) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) RSV Immunization Effectiveness and Safety for the 2026-2027 Respiratory Season (JAMA) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Moderna Receives U.S. FDA Approval for Updated 2026-2027 COVID-19 Vaccines (Moderna) Novavax's Partnership Strategy Continues to Deliver with XFG-adapted Nuvaxovid™ Approvals in the U.S., EU and Japan for 2026-2027 Vaccination Season (novavax) Pfizer and BioNTech Receive U.S. FDA Approval for XFG-adapted COVID-19 Vaccine (Pfizer) FDA approves new COVID vaccines (CIDRAP) Baseline interferon signaling in monocytes and antibody-mediated innate activation are associated with reactogenicity to mRNA vaccines (Science Translational Medicine) Coronavirus Disease 2019 (COVID-19) Hospitalization Surveillance Network (COVID-NET)(CDC: Covid) CDC inaction delays COVID shots for low-income children (CIDRAP) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Loss of vesicular monoamine transporter 2 in striatum of long COVID and relationship to neuropsychiatric symptoms (eBioMedicine) Reaching out to US house representative Letters read on TWiV 1360 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

Subscribe to the Better Part podcast today! Gospel reflection for 3-6 year olds for the 26th Sunday in Ordinary Time, year A. (Adults, the Gospel for this Sunday considers moral behaviour. For the youngest children it is important that they know for whom they are choosing to behave in a certain manner, before considering what that behaviour should be. In fact, we can say that this is vital, since God invites us into covenant relationship. We want the children to fall in love with God; all behaviour will flow out of this relationship. The following reflection therefore, considers Who God Is.)

A Mediocre Time with Tom & Dan: Episode Notes Episode: "69 Come Sticks" (#894) Hosts: Tom Vann, Dan Dennis | Guest: Ross McCoy (comedian, The Orlando Talk Show) Sponsors / Ad Reads Bart the Realtor / The Bart Marek Team: Opened with a host doing a "cool dude" character, then Bart called in. He said Central Florida real estate is having a rough, locked-up year because 30-year rates are near 7.25%. Cash buyers have the edge, and homes that have sat for a month or more have room to negotiate. His team is also doing a lot of estate, job-loss, and divorce sales. barttherealtor.com has cell numbers for Bart Marek and Crystal Vann. Bart has been a gold star sponsor for nearly 15 years. Seaz Nuts 2027 Tom & Dan Cruise: On the MSC Seashore out of Port Canaveral, with stops in Nassau and Ocean Cay. Interior staterooms start at $1,200 for two and include Wi-Fi, in-room breakfast, and a premium drink package (15 drinks a day). There will be a live broadcast and the Mediocre Idol karaoke contest. Deposits at tomanddancruise2027.com. Injured On The Go / Just Call Moe (justcallmoe.com): Studio sponsor, also named as a cruise sponsor. Trail of Terror "Sweet 16": At Peghorn Nature Preserve in St. Cloud, six dates only. Tickets are $15 in advance or $20 at the door, via the zombie girl link on TomandDan.com. Supported by Experience Kissimmee and Orlando Health St. Cloud Hospital. Modern Plumbing Industries (modernpi.com): Mention Tom & Dan for 10% off. The read included a listener story about a sewer backup coming up a shower drain. They cover all Central Florida counties, residential and industrial, including cast iron pipe relining. My Eternal Vitality (myeternalvitality.com): A quick drop-in plug during the Method Man TRT joke. Cruise sponsors: justcallmoe.com, Empire Spot Fireworks, Celery City Craft, Villain Coffee / Villain Roasters. Segment Rundown Cold open: cool dude character. The Bart ad read was framed around a revived "cool dude" character that Bart likes. Afterward the hosts argued over how to sign off after a sponsor read. Cruise update: $20 bump. Dan debuted a new "Yachty" sound effect. The first block of balcony cabins sold out, and Tony from Ahoy Cruises got a second block at $20 more, which he was angry about for the listeners' sake. Inside cabins are still at the original price, but another block could cost more. Deposits are fully refundable until a couple of months before sailing. The hosts mocked anyone who cancels. Falcons and Garth tonight. Tom was still wound up after the Falcons game, where a rough first quarter gave way to a strong performance. Moe DeWitt invited the crew, Ross included, to the Garth Brooks show at the Kia Center that night. They joked about how many people dropped out before Tom and Dan got invited, and guessed Buzz Stecker would skip it. Crystal had been playing Garth's greatest hits on Amazon Music (the audio quality got panned), and a host's daughter caught him in "Garth mode." Favorites included "Callin' Baton Rouge" and "Friends in Low Places." Billionaire musicians quiz. A report that Garth considered selling his catalog, valued around $2 billion, led into a guessing game about the six billionaire musicians. The crew landed Jay-Z, Beyonce, Paul McCartney, Taylor Swift, and Rihanna. Rihanna got an asterisk because most of her money comes from her cosmetics line. Ross also floated "A billion is a lot" as a T-shirt. Chris Gaines deep dive. Dan went down the Chris Gaines rabbit hole: Gaines was written as a fictional Australian rock star from Brisbane, with a made-up back catalog. The album was meant to set up a movie called The Lamb, a thriller about a fan trying to prove Gaines was murdered. The character was written as a sex addict, and Garth would have needed an Australian accent. The album sold about 2 million copies and became Garth's only Top 40 pop hit. The SNL episode where Garth hosted and introduced Gaines as the musical guest confused a host's dad. The hosts compared the idea to Borat and to found-footage horror. A host remembered seeing a found-footage film at the Enzian with its UCF filmmakers and believing it was real. Caller Cara: nanny stories. Cara was a nanny for a top makeup artist who worked with Garth, Faith Hill, Reba and others. She said Garth's team went along with the Gaines look because nobody told him no. She lived on the artist's property in her early 20s and fried okra and chicken at Faith Hill's Southern-style baby shower. The artist's husband played in Barbara Mandrell's band. The hosts brought up Tom's childhood nanny again. They also recalled the Gaines album ending up in bargain bins once record stores over-ordered. Garth, music rights, and yes-men. Garth fought used-CD stores in 1995, resisted iTunes, and launched his own download service, GhostTunes, later absorbed into Amazon Music. The hosts roasted his naming choices: GhostTunes, The Lamb, a fake Gaines album called "Fornicopia," and his production company Red Strokes. Tom created the "Castleberry Garth" bit about rich stars who won't take notes from employees. Claims from a 2013 lawsuit by an ex-business partner: Garth supposedly passed on Twister (the Helen Hunt role) and Saving Private Ryan to avoid sharing the spotlight. His Padres spring training stint was for charity (a donation to Boys & Girls Clubs), not a real tryout. Dan admitted arguing with Claude about it before conceding. Pre-internet news coverage made stunts like this confusing. Caller Charles: concert parking. BDM Charles was taking his wife to the Garth show for their 23rd anniversary and asked for parking tips. The hosts first gave joke advice: tip a random guy in a construction vest to valet your car. Then came real tips about the Kia Center lots and a gate most people don't know about. Dan's partner Andrea has a secret back-alley parking route. The crew planned crispy tavern-style pizza downtown and Uber rides home. Ross's Uber nightmare. After Wu-Tang Clan at the MidFlorida amphitheater in Tampa, Ross and his wife could see their Hard Rock hotel balcony but had I-4 in the way. Rideshare signs led them nowhere, and the app's pickup point was a slab of concrete in an empty fairgrounds field. The driver stayed in a different lot and stopped answering, while black SUVs kept offering rides. They ended up walking toward a distant Hampton Inn. Chat and hosts piled on about Uber's decline (rider-rating filtering, cancellations) and a Waymo that got stuck in traffic. Break: ska block. The Family Business Limited's "Still a Jamaican" (new album out today) and the Barstool Preachers' "Want to Know" (pick of the week), followed by the Trail of Terror read. Oviedo e-bike arrest. A News 6 clip covered an 11-year-old in Oviedo who got a written arrest for riding a Sur-Ron-style electric dirt bike near Sweetwater Park. He bought it with $900 from selling squirrel picnic tables. The charges were an unregistered vehicle, no insurance, no motorcycle endorsement, and no eye protection. His father called it an overreach, and the boy will miss school for court. Tom recalled his brother getting a written arrest for riding a dirt bike on the street. Officer interview: e-bike law. A BDM police officer (name unclear in the transcript) called in: The crackdown follows a wave of crashes and kids getting hurt, plus newer statutes that classify e-bikes. With working pedals it's a bicycle. With the pedals removed it's a motor vehicle. Fake pedals may get riders by some officers. Enforcement is at the officer's discretion: a civil infraction with a misdemeanor consequence. Registering a Sur-Ron takes blinkers, lights, and a plate. Dan's old scooter has only an antique tag. Stand-up scooters are speed-regulated, and OneWheels are unregulated. You can get a DUI on anything motorized. Adults can be charged for letting an unlicensed minor drive. Traffic court has a hearing officer, not prosecutors. Seminole County is stricter than Orange. Afterward the hosts wondered how their Miami friend Turkey Leg, who rides one, would react. Wu-Tang concert recap. Ross described the night: Bone Thugs-n-Harmony opened with medleys, including an Eazy-E tribute and a Biggie and Tupac tribute. RZA gave a spoken history of the group, then the set ran through 36 Chambers material and solo spots for Method Man, Ghostface, Raekwon, Cappadonna, and a Mobb Deep member. Method Man showed off his physique and hair, which set up the TRT joke. There was a memorial tribute to late rappers. The reveal: ODB's parts were performed by his son, Young Dirty Bastard. His mother tried to steer him away from music, and RZA didn't cast him in the American Saga series. The hosts traded ODB stories and tried, unsuccessfully, to play a TRL clip. Seacrest and aging. A host's parents cut cable and now use an antenna for NFL games, which means catching Ryan Seacrest on Wheel of Fortune. The crew discussed Seacrest's changed face, weight loss versus cosmetic work, and his frosted tips at his age. Vanna White came up too. Tom said he's getting gray streaks and would dye his hair, which got jokes about jet-black "magician hair." Elizabeth Holmes documentary. Nathan Fielder's secretive Holmes documentary screened at a festival with breathless reviews but no specifics. It's rated R for graphic nudity. The leading theory was that it includes a childbirth video. The crew expected a three-hour absurdist art piece and joked about betting on its reception on Kalshi. They noted a trailer scene where her husband takes the whisk from her while she's making eggs. Ross's theory: the story turns to Holmes cheating on him. That led to a tangent on Italian brainrot videos, Skibidi Toilet being over, "6-7," and how much Fortnite has changed. Break: pop punk block. Rivals' "Adrenaline Rush," the Modern PI read, and Cartel. "Mother of the Year" video. In a viral Giants broadcast clip, a mom juggles a baby, a carrier, and stacks of food and drinks back to her seat while her husband sits idle, and the announcers roast him. Tom defended the dad, saying partners who don't ask for help end up making the other person look bad. The others ribbed him for how he phrased it. Dan described Andrea handing off their daughter at Magic and Orlando City games so she could take a break. Ross offered a gentler defense, citing $25 concert beers and sending his wife to the beer tent. Dan shared Andrea's backhanded compliment that she's glad he drinks less, but "even this one scares me." Dripstick product. Ross got a targeted ad after Monday's cruise talk about tampons. The product is Awkward Essentials' Dripstick, a post-sex sponge applicator. The hosts read the instructions, then argued at length about hygiene and peeing after sex. Dan explained his cleanup routine, and Tom compared it to cleaning a paint sprayer or a beer line. The product's FAQ recommends peeing afterward anyway. The punchline was a "69 for $69" deal, which gave the episode its title, plus a joke return address on the "discreet packaging." Caller Toad King. Last call of the day: a crude one-liner about the post-sex topic, with nothing substantive. Tom's crazy fact: snakebites. The US averages about 5 snakebite deaths a year, and Tom asked the crew to guess India's number. The answer is about 58,000, mostly rural. The crew discussed the colonial snake-bounty story (often called an urban legend), India's "big four" venomous snakes, the Monsters of God documentary, and a story about someone stealing a nearly extinct tortoise breeding population. Plugs and wrap. Ross plugged The Orlando Talk Show and the Moe Comedy Jam. The cruise price increase got a reminder, and they announced Villain Roasters' new location with a possible Tom & Dan chicken-and-waffle item and a meetup. Key Dates / Plugs Mentioned Today (Friday): Garth Brooks at the Kia Center, with the crew attending as Moe DeWitt's guests. The Family Business Limited's new album is out. Next Tuesday: Court date for the Oviedo 11-year-old in the e-bike case. Monday: Next show. October 9 and 10: Trail of Terror, Peghorn Nature Preserve, St. Cloud. The 17th (month not specified): Moe Comedy Jam at the Orlando Funny Bone (formerly the Improv), hosted by Ross McCoy and Larry Helms, with Will Blalock, Amy LaCour, and Sean Fenergate. Tickets at MoeComedyJam.com. Tom, Dan, and Colette will be there. October 16 and 17: Trail of Terror. October 23 and 24: Trail of Terror. These late dates are expected to sell fastest. Tickets are $15 in advance or $20 at the door via TomandDan.com. Soon: Villain Roasters opening in the former Goombay spot in Satellite Beach, with a possible Tom & Dan chicken-and-waffle item and a meetup. Ongoing: Bart Marek Team at barttherealtor.com. Modern PI at modernpi.com (10% off). Just Call Moe at justcallmoe.com. The Orlando Talk Show. Easy Moe with Joe (Moe DeWitt, DeWitt Law Firm, and Joe Byrne, Byrne Pest Control). Up to a couple of months before sailing: Cruise deposits are fully refundable. Thursday, September 23 to Sunday, September 26, 2027: Seaz Nuts 2027 Tom & Dan Cruise on the MSC Seashore. Deposits at tomanddancruise2027.com. Balcony cabins are now in a second block at $20 more. Notable Guests/Callers Ross McCoy: In-studio guest for the full show. He's a comedian and host of The Orlando Talk Show. Bart Marek: Sponsor call-in with the real estate market update. Cara: Caller who was a nanny for a top 90s makeup artist, with stories about Garth's team and Faith Hill's baby shower. BDM Charles: Caller asking for Kia Center parking tips before taking his wife to Garth for their 23rd anniversary. BDM police officer (name unclear in the transcript): Phone guest who explained Florida e-bike, scooter, and OneWheel rules and traffic court. Toad King: Last caller of the day, with a crude one-liner.

INTRODUCTION:Fever of Unknown Origin, or FUO: We have all had a fever at some point—maybe from seasonal flu or a brief stomach bug—where the body turns up the heat, fights off the bug, and recovers in a couple of days. Fever is a very efficient defense mechanism to fight microorganisms by making your body a hostile environment where they cannot survive. But what happens when a fever lasts for weeks, standard tests come back normal, and usual fever reducing medications do not seem to work?We will talk about the surprising root causes, the latest imaging technology like PET scans, and what to do when a fever refuses to break. Whether you are a medical student, a healthcare professional, or simply curious about how our body's defense mechanisms work, this episode is for you. Let us get into it!Definition of Fever of Unknown Origin.A standard fever is like a smoke alarm going off when you burn toast—you quickly spot the cause, fix it, and the alarm stops. FUO is like an alarm ringing continuously for weeks, but despite searching every room, you cannot find the source of the fire.Clinical Criteria (Classic FUO):1. Temperature >38.3 C measured on multiple occasions.2. Duration of at least 3 weeks.3.Unexplained after 1 week of intensive outpatient or inpatient evaluation (or three outpatient visits).Categories of FUO.1. Classic FUO: The traditional presentation described above.2. Nosocomial (Hospital-Acquired) FUO: Fevers in hospitalized patients without infection upon admission.3. Neutropenic FUO: Fevers in immunocompromised patients (e.g., undergoing chemotherapy) with low white blood cell counts.4. HIV-Associated FUO: Fevers lasting weeks in patients with HIV, often driven by opportunistic infections like Tuberculosis or CMV, that stands for cytomegalovirus. What a mouthful!The Big Four Causes are:Infections (~30–40%): Atypical presentations of common diseases (e.g., hidden abscesses, endocarditis, tuberculosis, or tick-borne illnesses). Our priority will be to determine if this patient is having an infection, unless we get clinical manifestations that would guide us in another direction.Autoimmune & Inflammatory Diseases (~20–30%): The immune system overreacting and attacking the body's tissues (e.g., Adult-onset Still's disease, Temporal Arteritis/Giant Cell Arteritis, Lupus).Malignancies / Cancers (~10–20%): Blood cancers (Lymphoma, Leukemia) or solid tumors (Renal cell carcinoma). Infections, autoimmune/inflammatory diseases, and malignancies cover 60-90% of the causes of FUO.Miscellaneous / Drug Fevers (~10–15%): "Drug fever" caused by adverse reactions to common medications (e.g., antibiotics, anti-seizure meds), thyroid storm, or deep vein thrombosis (DVT).Modern Medicine: Advanced imaging (CT, MRI, PET scans) which have helped us diagnose cancers and abscesses much earlier. As a result, modern FUOs are increasingly driven by autoimmune conditions, non-infectious inflammatory disorders. Sometimes it feels like we solve one problem and uncover another one!Important: Some cases remain undiagnosed (up to 30–50%) and resolve without a specific label.Diagnostic Approach:Step 1: The "Detective Work" (History & Physical):● Detailed History: Travel history, animal exposure (ticks, pets), occupational hazards, social history, medication review (to exclude drug fevers), and family history.● Potential Diagnostic Clues: Looking for subtle signals (e.g., a new heart murmur, temporal tenderness, hidden skin rashes, or swollen lymph nodes).Step 2: Basic Tiered Testing:● Blood Work: CBC (complete blood count), inflammatory markers (ESR, CRP, Ferritin), comprehensive metabolic panel, blood cultures.● Targeted Serologies: HIV, viral panels, autoimmune antibodies (ANA, Rheumatoid Factor).● Initial Imaging: Chest X-ray, abdominal ultrasound.Step 3: Advanced Diagnostic Workup:FDG-PET/CT Imaging: One of the most significant updates in recent guidelines. FDG-PET/CT uses a radioactive sugar tracer to highlight areas of high metabolic activity (inflammation, infection, tumor) throughout the entire body in a single scan. FDG-PET is a functional nuclear-imaging technique that uses ¹⁸F-fluoro-deoxy-glucose (FDG) — a radioactive glucose analog — to map tissue glucose metabolism.Targeted Biopsies: Biopsying tissues guided by PET scan findings (e.g., lymph node, liver, or temporal artery)."Refractory" Fevers:Fever vs. Hyperthermia: Standard fevers are driven by the brain's hypothalamus resetting the body's thermostat upward (often mediated by prostaglandins). ● Antipyretics (acetaminophen, NSAIDs) block prostaglandin synthesis.● If a fever does not respond to antipyretics, it may indicate non-prostaglandin-mediated inflammation (e.g., severe cytokine storm, drug-induced hyperthermia, or central nervous system dysregulation).Empiric Treatment vs. Observation:● The "Hold Your Horses" Principle: Current guidelines strongly advise against starting empirical antibiotics or steroids right away in stable patients. Antibiotics can mask infections and produce false-negative culture results, while steroids can hide inflammatory signs or exacerbate hidden infections.● When to Treat Empirically: Reserved for hemodynamically unstable patients, neutropenic patients, or specific high-suspicion conditions (e.g., suspected Temporal Arteritis to prevent blindness).Diagnostic Trial: Naproxen Test (Historical & Clinical Pearl): A brief trial of naproxen can sometimes distinguish tumor fevers (which often drop sharply in response to NSAIDs) from infectious fevers, though it is used cautiously as a supportive diagnostic clue rather than a rule. So, if a patient responds to a trial of naproxen, then we can suspect a tumor as a cause of the patient's fevers. But it is not a strong recommendation.A 2019 systematic review/meta-analysis (15 studies, 582 patients) found a 94.1% success rate for naproxen in treating confirmed neoplastic fever. The test is not specific and lacks validation, but I can see the importance of knowing this: Naproxen is effective against cancer fever.FUO evaluation is a marathon, not a sprint. Re-evaluating the patient daily in the hospital for new physical clues is often more valuable than ordering endless specialized tests. I would like to emphasize that modern tools PET/CT have transformed how quickly we locate hidden inflammation. Also, let us remember that a huge proportion of undiagnosed FUOs eventually resolve spontaneously with good long-term outcomes, provided serious conditions have been systematically ruled out.Take away messages:First, FUO is a diagnostic marathon, not a sprint. Finding the cause takes patient detective work, careful daily exams, and targeted testing rather than rushing into quick fixes.Second, modern imaging like FDG-PET scans has completely transformed how we spot hidden inflammation and infection long before standard blood work gives us an answer.And finally, 'refractory' fevers require caution. If a fever is not responding to standard antipyretics, starting antibiotics or steroids right away can hide the real culprit. In stable patients, holding off and continuing the search is often the safest path.__________________Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week!References:1) David AB, Quinlan JD. Fever of Unknown Origin in Adults. American Family Physician. 2022;105(2):137-143.2) Wright WF, Stelmash L, Betrains A, Mulders-Manders CM, Rovers CP, Vanderschueren S, Auwaerter PG; International Fever and Inflammation of Unknown Origin Research Working Group. Recommendations for Updating Fever and Inflammation of Unknown Origin From a Modified Delphi Consensus Panel. Open Forum Infectious Diseases. 2024;11(7):ofae298.3) Wright WF, Durso SC, Forry C, Rovers CP. Fever of unknown origin. BMJ. 2025;388:e080847.4) Wright WF, Auwaerter PG. Fever and fever of unknown origin: review, recent advances, and lingering dogma. Open Forum Infectious Diseases. 2020;7(5):ofaa132.5) Cunha BA, Lortholary O, Cunha CB. Fever of unknown origin: a clinical approach. The American Journal of Medicine. 2015;128(10):1138.e1-1138.e15.6) Nazar AH, Naswa N, Sharma P, et al. Spectrum of 18F-FDG PET/CT findings in patients presenting with fever of unknown origin. American Journal of Roentgenology. 2012;199(1):175-1851) Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/. Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week!

Toys "R" Us is coming back... but they want you to grow up. And get a job. And buy adult collectibles for adults who have money. Yes, kids aren't into toys so the new TRU will focus on middle-aged pay pigs. Watch the podcast episodes on YouTube and all major podcast hosts including Spotify. CLOWNFISH TV is an independent, opinionated news and commentary podcast that covers Entertainment and Tech from a consumer's point of view. We talk about Gaming, Comics, Anime, TV, Movies, Animation and more. Hosted by Kneon and Geeky Sparkles. Get more news, views and reviews on Clownfish TV News - https://more.clownfishtv.com/ On YouTube - https://www.youtube.com/c/ClownfishTV On Spotify - https://open.spotify.com/show/4Tu83D1NcCmh7K1zHIedvg On Apple Podcasts - https://podcasts.apple.com/us/podcast/clownfish-tv-audio-edition/id1726838629 MORE CLOWNFISH TV - Official Merch Store: http://ClownfishMinus.com Facebook - https://facebook.com/ClownfishTV X - https://x.com/ClownfishTVcom Clownfish TV subreddit: https://www.reddit.com/r/ClownfishTVOfficial/ Disclaimer: This series is produced by Clownfish Studios and WebReef Media, and is part of ClownfishTV.com. Opinions expressed by our contributors do not necessarily reflect the views of our guests, affiliates, sponsors, or advertisers. ClownfishTV.com is an unofficial news source and has no connection to any company that we may cover. This channel and website and the content made available through this site are for educational, entertainment and informational purposes only. These so-called “fair uses” are permitted even if the use of the work would otherwise be infringing. #Podcast #Commentary #News #Reaction #Gaming #Comedy #Entertainment #Hollywood #PopCulture #Tech #Anime #FYP Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Gilly Kahn, Ph.D. is a clinical psychologist, writer, and mother with ADHD. She practices in Atlanta and specializes in neurodiversity. She is the author of Allow Me to Interrupt: A Psychologist Reveals the Emotional Truth Behind Women's ADHD. You can learn more about Gilly and her work by visiting her website at https://www.drgillykahn.comIn this episode, we explore ADHD beyond the common stereotypes, including how it can show up in high-achieving adults and the ways neurodivergence can shape our experiences, relationships, and ability to pursue goals. We also discuss emotional dysregulation related to ADHD, common misconceptions, ADHD and autism, navigating barriers to diagnosis and support, and the grief that can come with recognizing how ADHD has impacted different areas of your life.We also explore rejection sensitivity dysphoria (RSD), along with overlaps and important differences between ADHD and OCD. We hope this conversation can offer a nuanced look at living with ADHD in adulthood.FOLLOW DR. KAHN:INSTA: @drgillykahnWEBSITE: www.drgillykahn.comBOOK: Allow Me to Interrupt STAY CONNECTED:INSTA: @trustandthriveTIKOK: @trustandthriveTHREADS: @trustandthriveFACEBOOK: bit.ly/FBtaramontEMAIL: trustandthrive@gmail.com

Mike D Album, Resonance: A Plague Tale Legacy, Heroine? Saint? No, I'm an All-Works Maid, 100 Girl Friends Who Really, Really, Really Love you and more on We Are Adults? Show!

How can learning to reframe difficult childhood interactions empower both parents and adults to navigate emotional energy and adult bullying? In this episode of The Slight Shift Show, hosts Chris and Angela dive into the world of social dynamics, parenting, and emotional resilience. Prompted by a recent schoolyard challenge experienced by Angela's daughter, the conversation explores how early interactions shape our adult perspectives. Together, they discuss actionable strategies for handling negativity, defusing conflict, and taking control of internal responses. Key Discussion Points: Reframing & The Power of "Thank You": Simple tactics to de-escalate teasing, including using gratitude to neutralize mean-spirited tone. Adults as "Older Children": Understanding that adult bullying stems from the same internal insecurities and attention-seeking behaviors seen in childhood. Managing Emotional Energy: The "coffee cup" metaphor, recognizing that what spills out during life's bumps depends on what you allow inside. The Martial Arts Approach (ABCs): Applying awareness, boundaries, and self-defense principles to daily emotional challenges. Always Be Caring: Shifting focus toward caring for oneself, minding personal energy, and practicing self-compassion.

When autistic kids struggle, their difficulties are often treated as behavioral non-compliance or a lack of social desire, when it's often a direct mismatch with the learning environment. Adults routinely push these students into sensory-heavy spaces or force sudden task shifts, misunderstanding the neurological toll this takes on a differently wired nervous system. Pete Wharmby, an autistic author, former teacher, and late-diagnosed ADHDer, joins Emily Kircher-Morris to talk about what happens when schools and families learn to support rather than correct autistic ways of being. TAKEAWAYS Autistic behavior in schools is often pathologized and targeted for correction when it's likely a natural, necessary drive to decompress from sensory overload. Monotropic focus operates like driving on a high-speed freeway, where abrupt task transitions resemble crashes and require gradual advance warning signs to exit safely. Thin-slice judgments cause adults to mistake natural autistic communication, such as flat tone or lack of eye contact, for intentional rudeness or disrespect. High academic performance can mask emotional distress, with deep exhaustion and low frustration tolerance serving as the real markers of masking. Receiving late diagnoses of autism and ADHD often creates complex grief over missed accommodations and unmedicated years that could have prevented chronic burnout. The doors to the Neurodiversity University Educator Hub are now open! Click here to join our collective of educators, administrators, and advocates, and let's build an education system that works for all students. Pete Wharmby is an autistic and ADHD advocate, bestselling author, and international speaker dedicated to increasing understanding and acceptance of neurodivergence. Since his autism diagnosis in 2017 and ADHD diagnosis in 2024, Pete has worked with businesses, governments, schools, and organizations across the UK, Europe, Australia, and North America, sharing practical insights drawn from both lived experience and research. Pete is the author of the bestselling books What I Want to Talk About, Untypical, and the forthcoming Different Minds. A former secondary English teacher, he is also a prolific writer whose work has appeared in articles, interviews, and book chapters, and he has been featured on BBC Radio 2. Through his speaking, writing, and social media platforms, where he reaches more than 150,000 followers, Pete continues to champion a more neurodiversity-affirming world. BACKGROUND READING Peter's website, Facebook, Instagram The Neurodiversity Podcast is on Facebook, Instagram, BlueSky, and you're invited to join our Facebook Group. For more information go to www.NeurodiversityPodcast.com If you'd like members of your organization, school district, or company to know more about the subjects discussed on our podcast, Emily Kircher-Morris provides keynote addresses, workshops, and training sessions worldwide, in-person or virtually. You can choose from a list of established presentations, or work with Emily to develop a custom talk to fit your unique situation. To learn more, visit our website. Thank you for supporting neurodivergent people.

Most adults believe AI companies need to slow down the progression of the technology.See omnystudio.com/listener for privacy information.

Lawmakers and immigrant rights groups urge Governor Gavin Newsom to sign a bill that bars police from side gigs in immigration enforcement. A new USC study on alcohol usage. The Anaheim Ducks name the tenth captain in the team's history. Plus, more on Evening Edition. Support The L.A. Report by donating at LAist.com/join and by visiting https://laist.comSupport the show: https://laist.com

Parents often believe they are showing love by affirming every feeling, avoiding firm boundaries, or making life revolve around their children. But those choices can leave children unprepared for adulthood.In this episode, I examine five common parenting lies and how they affect a child's relationship with truth, authority, emotions, sacrifice, and responsibility. You are not merely raising children. You are raising future adults, and the lessons they learn now will shape how they approach work, marriage, family, and faith later in life.

What are the things we couldn't stand when we were younger that we now appreciate as adults? Dan and Brandon put together their own Man Cave draft, picking the things they were told they'd eventually understand, appreciate, or even love — from school and vegetables to beer, coffee, early bedtimes, staying home, and more. But before the draft, the guys tackle a bigger sports question: how much should fans actually trust analytics? Are advanced statistics helping us understand players and teams, or are we sometimes just throwing numbers into an argument because they sound impressive? Dan and Brandon discuss Pro Football Focus, WAR, EPA, box scores, player grades, and why context still matters when evaluating athletes. Plus, Dan tries a Hamm's for the first time, the guys settle on their next Man Cave draft — the Top 5 Fullbacks of All Time — and another round of the Shake 7-14-21 game determines who has to bring the next beverage. It's another unscripted conversation about sports, getting older, and the things we eventually realize our parents were right about. The Man Cave Podcast — no scripts, no forced takes, just Man Cave talk.See omnystudio.com/listener for privacy information.

Neurodivergence doesn't look the same in everyone. Some people learn to mask traits they believe set them apart, while others don't recognize their symptoms until college or early adulthood. For some, it can mean years of being treated for other conditions before considering autism, ADHD or OCD. But even once someone suspects they may be neurodivergent, getting a diagnosis can be time-consuming and expensive. However, more adults are asking these questions. A study from the Ohio State University College of Medicine found that 1 in 4 adults surveyed suspected they had undiagnosed ADHD, but only about 13% of the group had discussed that suspicion with a healthcare professional. Autism diagnoses among children have also increased substantially over the last two decades, leading to a rise in adult diagnoses as the condition becomes better understood. More people are sharing their stories online and terms like masking and stimming have entered everyday conversation. Even tools once marketed primarily for people with sensory or attention needs, like fidget toys, have become mainstream. Wednesday on the "Sound of Ideas" hosted by Stephanie Haney, we'll talk with Northeast Ohioans whose diagnoses came later in life and learn what changed once they had answers to questions they'd carried since childhood. Guests:- Andrew Parker, Author and Advocate, “Life Is a Joke and I'm The Punchline”- Doug Blecher, Founder, Autism Personal Coach and Neurodiverse Culture Festival- Tasha Simpson, AuDHD Content Creator, Entrepreneur, Theatre Artist- Karen Krainz-Edison, Associate Director of College Support Programs, The Ohio State University Nisonger Center- Joy Harris, Leader, Stark County OCD Support Group

Don't miss Billy Joe's hometown celebration this Saturday in Rodeo. Carrie Underwood is thinking about putting out a rock album. Sarah says it all comes down to the song. Ozzfest is returning to the US. No investigation necessary, Taylor Swift WILL be at the VMAs. Need inspiration today? These famous singers were all rejected from The Voice. Taylor Swift has a countdown on her website! Sarah says not to hold your breath. A long lost painting sold for $30! Pumpkin spice season is upon us! And if this is your last season, there's now an option to enjoy PSL forevermore. Adults are sharing the wildest things they've had to explain to other adults. PSA: Alaska isn't an island. Let's hear what everyone thinks about Matty's massage table. Plus, When Did That Happen?

Hour 1: Vinnie's wife is standing up for Sarah. Speaking of Sarah, she's telling us bad news. More details surrounding Presley Gerber's overdose have been revealed. Carrot Top remains hospitalized. Then, A Random Story Out Of Nowhere: Top 10 movie quotes everyone knows. Today is the equinox - is gravity impacted? Superstitions play out in the real world. AI helped with a new mathematical breakthrough. A NY influencer on the quest to find America's top party school. Hour 2: The Further Misadventures of Cliff Booth will be on Netflix, and it takes place 10 years later. Taylor Frankie Paul quits Secret Lives of Mormon Wives. Meghan Markle is hanging out with Ellen DeGeneres in the UK. Gavin Newsom declares a state of emergency for the pending El Nino. The kids have a new photo pose. It's giving “flirty” and “caught off guard.” The generational divide strikes again: Will bringing a coffee into an interview cost you the job? Hour 3: Arnold Schwarzenegger is in the news. Remember when he became governor? Happy Tuesday! Enjoy a cup of Burt Reynolds tea - on the house. Venice Film Festival premiered a movie where Kate and Rooney Mara are playing twisted twins. Channing Tatum denies he is responsible for the burner Instagram account. It was fun while it lasted. Cake cone or sugar cone? Any excuse for an ice cream cone! Hugging vs. handshake - it is that complicated. A place has opened in China where they scratch their back. The crazy part is the gloves they wear to do it. Hour 4: Don't miss Billy Joe's hometown celebration this Saturday in Rodeo. Carrie Underwood is thinking about putting out a rock album. Sarah says it all comes down to the song. Ozzfest is returning to the US. No investigation necessary, Taylor Swift WILL be at the VMAs. Need inspiration today? These famous singers were all rejected from The Voice. Taylor Swift has a countdown on her website! Sarah says not to hold your breath. A long lost painting sold for $30! Pumpkin spice season is upon us! And if this is your last season, there's now an option to enjoy PSL forevermore. Adults are sharing the wildest things they've had to explain to other adults. PSA: Alaska isn't an island. Let's hear what everyone thinks about Matty's massage table. Plus, When Did That Happen?

FASD specialist and adoptive mom Sandra Flach joins Jesse to break down fetal alcohol spectrum disorder: what it actually is, why it hides behind behavior nobody understands, and why it's one of the most common and least discussed disabilities in foster care and adoption. Sandra shares her own family's diagnosis journey and the accommodations-based approach that finally helped her understand her sons instead of just managing their behavior. It's a conversation for anyone parenting a child whose brain might be working differently than expected, diagnosed or not. Sandra Flach is co-founder of Justice for Orphans and an adoptive and kinship parent of six. After her own sons were diagnosed with fetal alcohol syndrome, she became a national voice on FASD, offering training, coaching, and a peer support community for foster and adoptive families. Website: Justice for Orphans: FASD Training & Support Key Takeaways FASD is far more common than most people realize (one in twenty people prenatally exposed to alcohol, up to seventy percent of kids in foster care), yet true diagnosis is rare because doctors are trained to look for facial features present in fewer than ten percent of cases. FASD symptoms overlap heavily with trauma and can look like willful defiance, but the brain difference is real: what looks like "won't" is usually "can't," especially around executive function, auditory processing, and daily living skills. The path forward is accommodation, not consequence: understanding a child's specific struggles (memory, impulse control, sensory processing) and adjusting expectations the same way we already do for visible disabilities. Timestamped Outline 00:00 – Introduction: meet Sandra Flach, adoptive and kinship mom, FASD specialist and advocate 00:01 – FASD 101: how common it actually is, and why it's called an invisible disability 00:08 – Getting a diagnosis: who can diagnose FASD, and why so few doctors do 00:13 – Why the standard diagnostic criteria miss 90% of cases 00:19 – Not a straight line: the "scribble" and FASD's scattered developmental profile 00:28 – Why it's not that they won't, it's that they can't: executive function and the brain 00:36 – The neurobehavioral approach: accommodations instead of consequences 00:40 – "A child with brain damage": the reframe that changed how Sandra saw her sons 00:46 – Grief, interdependence, and redefining what success looks like 00:52 – Untangling shame, for parents, kids, and birth parents 01:03 – The long view: daily living skills, connection, and "not yet" instead of "never" 01:07 – Where to find Sandra: her support group, training, podcast, and a free gift Resources Mentioned Justice for Orphans: FASD Training & Support Hope Community (Sandra's online FASD support group) The Adoption & Foster Care Journey podcast Sandra Flach's site (Soul Care Saturday devotional and free breath prayers download) Call to Action (CTA) ETC Shopify ETC Newsletter signup ETC Instagram ETC Facebook Chapters (00:00:00) - Introduction and Sandra's Background(00:01:46) - What Is Fetal Alcohol Spectrum Disorder(00:03:30) - Sandra's Family Journey to Diagnosis(00:07:57) - Challenges Getting an FASD Diagnosis(00:10:36) - Alcohol as a Teratogen and Whole-Body Effects(00:12:58) - Diagnosis Barriers and Facial Features Myth(00:14:17) - Navigating Diagnosis Without Birth History(00:18:48) - Developmental Gaps and Scattered Abilities(00:26:22) - Coping Strategies and Stress Capacity(00:28:21) - Executive Function and Misunderstood Behavior(00:30:28) - Communication Challenges and Real-Life Examples(00:33:55) - Untangling Trauma vs FASD Symptoms(00:35:54) - Accommodations as a Neurobehavioral Approach(00:39:36) - Seeing Brain Differences Instead of Bad Behavior(00:42:19) - Adults with FASD and Lifelong Accommodations(00:44:17) - Grieving Expectations and Celebrating the Child(00:47:58) - Community, Support Groups, and Celebrating Wins(00:52:04) - Addressing Shame and Building Acceptance(00:57:38) - Dispelling Shame Around Alcohol and Pregnancy(01:03:16) - Long-Term Goals and the Power of Connection(01:06:58) - Closing Resources and Farewell

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