Podcasts about clinically

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Best podcasts about clinically

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Latest podcast episodes about clinically

HINESIGHTS Podcast
Full Episode | Clinically Related + Hinesights Podcast Collaboration | Aleksei Archer | Dr. Marlon Rollins | EP 168

HINESIGHTS Podcast

Play Episode Listen Later Jan 1, 2026 32:39


Clinically Related + Hinesights Podcast Collaboration | Aleksei Archer | Dr. Marlon Rollins | EP 168

The Hormone Genius Podcast
S6 Ep. 16: AMH, Fertility, and the Truth Women Need to Hear with OB/GYN Dr. Kristina Pakiz

The Hormone Genius Podcast

Play Episode Listen Later Dec 31, 2025 38:42


In this episode of The Hormone Genius, we are joined by expert OB/GYN Kristina Pakiz, founder of Vivify Women's Health and Fertility, for an honest, evidence-based conversation about fertility testing, specifically AMH (Anti-Müllerian Hormone), and what it does and does not tell women about their ability to conceive naturally. Dr. Pakiz brings years of clinical experience caring for women across the reproductive lifespan, with a special focus on restorative, patient-centered fertility care. Her approach emphasizes education, individualized evaluation, and empowering women with accurate information rather than fear-based lab interpretations. What Is AMH? AMH is a hormone produced by the granulosa cells of small, developing follicles in the ovaries. Clinically, it is often described as a marker of ovarian reserve, meaning it gives an estimate of how many recruitable follicles remain—not how well those eggs function, and not whether a woman can conceive naturally. Because AMH levels tend to decline with age, they are frequently used in fertility clinics to help predict response to ovarian stimulation in assisted reproductive technologies like IVF. Why AMH Is Not a Good Marker of Natural Fertility One of the most important takeaways from this episode is that AMH is often misunderstood and over-applied, especially in younger women. Dr. Pakiz explains that: AMH does not predict whether a woman can get pregnant naturally Women with low AMH can and do conceive spontaneously Women with high AMH may still struggle with ovulation, cycle irregularity, or other fertility barriers AMH does not assess egg quality, ovulation timing, uterine health, cervical mucus, or hormonal balance In other words, AMH reflects quantity, not function, and fertility depends on far more than follicle count. The Harm of Over-Interpreting AMH Dr. Pakiz also addresses the emotional and clinical harm that can occur when AMH is presented as a “fertility score.” Many women are told they are “running out of time” or that pregnancy is unlikely based on AMH alone, messages that are often inaccurate and unnecessarily distressing. Dr. Pakiz describes the alternative of NaproTechnology/Restorative Reproductive Medicine. Exciting NEWS!!! The Fertile Hive is a Buzzing Community designed for women interested in boosting their natural fertility through restored health. The infertility journey requires a guide whose knowledge and expertise can cut through the noise and provide clarity. Dr. Kristina Pakiz and Naomi Davis, PA-C provide this guidance through education. Women are empowered to be "the Queen of their own fertility", and the community provides the support needed for members to confidently choose their path to healing. The Fertile Hive is the ONLY membership community of its kind- a truly safe space where women with infertility can thrive. We are launching this membership community with a contest! The top 20 contestants win a free membership for a year! Each submission includes a short video clip answering a few simple questions. Submit your entry by January 16, 2026 at thefertilehive.com and look for the Queen Bee. Second, our brand-new Perimenopause Course is officially live. For just $97, women can dive into a simple, science-backed approach to navigating hormonal shifts with clarity, confidence, and peace. A big thank-you to our episode sponsor, We Heart Nutrition, a company we love for clean, effective supplements that support whole-body hormone health. Visit www.weheartnutrition.com and use code GENIUS for 20% off your first order. The information presented in The Hormone Genius Podcast is for informational purposes only and is not intended to be a substitute for actual medical or mental health advice from a doctor, psychologist, or any other medical or mental health professional.

In conversation with...
Presented at ASH: API-CAT post-hoc analysis on predictors of clinically relevant bleeding during extended anticoagulation for cancer-associated VTE

In conversation with...

Play Episode Listen Later Dec 31, 2025 9:55


Professor Isabelle Mahé joins us to discuss the results of a post-hoc analysis of the API-CAT trial identifying predictors associated with clinically relevant bleeding during extended anticoagulation for cancer-associated venous thromboembolism.Click here to read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(25)00291-1/fulltextContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

Brawn Body Health and Fitness Podcast
Terris Dior Hightower, Justin Lewis, Mike Lehr: Foot & Ankle Pathomechanics in Sport Performance and Rehabilitation

Brawn Body Health and Fitness Podcast

Play Episode Listen Later Dec 29, 2025 51:02


In the final episode of the 2025 season, Dan is joined by Dr. Terris Hightower, Dr. Justin Lewis and Dr. Mike Lehr to dive into foot and ankle mechanics. Terris Dior Hightower:Terris Dior Hightower, DPT, is a physical therapist and specialist in foot and ankle pathomechanics, with a focus on applied biomechanics, injury mechanisms, and performance optimization. He has worked across professional basketball environments, including the Washington Wizards, Washington Mystics, and Capital City Go-Go, supporting athletes through sports science, rehab, and performance roles. Terris bridges research and real-world application to challenge conventional thinking around lower-extremity injuries and tissue stress. Follow Terris on Instagram: @dr.terrishighpowerMike Lehr: Dr. Lehr is currently an associate professor in the Doctor of Physical Therapy Program at Messiah University. His areas of interest and expertise are in orthopedic and sports physical therapy, teaching and learning, manual therapy for the foot and ankle, movement assessment techniques, and musculoskeletal injury prevention strategies. Dr. Lehr has had extensive higher education teaching experience as a core faculty member in an entry level doctoral physical therapy program. Clinically, he still maintains clinical practice in the outpatient setting. He is an accomplished scholar with numerous peer reviewed scholarly products over the last decade at the national and international level and has been lead instructor for many continuing education courses related to his area of expertise. For more on Dr. Lehr, you can check out his research gate here: www.researchgate.net/profile/Michael-LehrJustin Lewis, DPMJustin Lewis is a surgically trained podiatrist specializing in sports medicine and complex foot and ankle pathology. With a background in exercise physiology, Justin brings a biomechanics-driven approach to athlete care, integrating advanced imaging, gait analysis, and innovative surgical techniques. His clinical interests include sesamoid injuries, bone stress injuries, and athlete-specific treatment strategies focused on preserving performance and long-term foot function.Instagram: ⁠https://www.instagram.com/justinlewis_footsurgery⁠Website: ⁠https://www.mdfootandankle.com⁠Season 6 and 7 of the Braun Performance & Rehab Podcast is brought to you by Pura Health - Bringing ultrasound into every clinician's hand. For more on Pura Health be sure to check out https://www.purahealth.net & @pura.health_ultrasound*SEASON 6 of the Braun Performance & Rehab Podcast is brought to you by Isophit. For more on Isophit, please check out isophit.com and @isophit -BE SURE to use coupon code BraunPR25% to save 25% on your Isophit order!**Season 6 of the Braun Performance & Rehab Podcast is also brought to you by Firefly Recovery, the official recovery provider for Braun Performance & Rehab. For more on Firefly, please check out https://www.recoveryfirefly.com/ or email jake@recoveryfirefly.com***This episode is also powered by Dr. Ray Gorman, founder of Engage Movement. Learn how to boost your income without relying on sessions. Get a free training on the blended practice model by following @raygormandpt on Instagram. DM my name “Dan” to @raygormandpt on Instagram and receive your free breakdown on the model.Episode Affiliates:MoboBoard: BRAWNBODY10 saves 10% at checkout!AliRx: DBraunRx = 20% off at checkout! https://alirx.health/MedBridge: https://www.medbridgeeducation.com/brawn-body-training or Coupon Code "BRAWN" for 40% off your annual subscription!CTM Band: https://ctm.band/collections/ctm-band coupon code "BRAWN10" = 10% off!Ice shaker affiliate link: https://www.iceshaker.com?sca_ref=1520881.zOJLysQzKeMake sure you SHARE this episode with a friend who could benefit from the information we shared!Check out everything Dan is up to by clicking here: https://linktr.ee/braun_prLiked this episode? Leave a 5-star review on your favorite podcast platform

The Jordan Harbinger Show
1263: Near Death Experiences | Skeptical Sunday

The Jordan Harbinger Show

Play Episode Listen Later Dec 28, 2025 53:29


Are near-death experiences proof of an afterlife — or just the brain's final fireworks? Michael Regilio goes into the light to find out on Skeptical Sunday!Welcome to Skeptical Sunday, a special edition of The Jordan Harbinger Show where Jordan and a guest break down a topic that you may have never thought about, open things up, and debunk common misconceptions. This time around, we're joined by skeptic, comedian, and podcaster Michael Regilio!Full show notes and resources can be found here: jordanharbinger.com/1263On This Week's Skeptical Sunday:Near-death experiences are real experiences — but that doesn't make them supernatural. NDEs happen to ordinary people during medical crises, and while skeptics question the metaphysical claims, no one disputes the profound personal impact. These aren't grifts or delusions — they're genuine neurological events that often leave people calmer, kinder, and less afraid of death.The "tunnel of light" isn't universal — it's cultural. Western NDEs feature tunnels and beings of light, but Buddhist and Hindu experiencers often describe rivers, bridges, or ancestors. This cultural filtering suggests NDEs are brain-based events shaped by personal beliefs — not visits to a one-size-fits-all afterlife waiting room."Clinically dead" doesn't mean the brain has completely shut down. Proponents argue NDEs prove consciousness survives death because brains were "flatlining" — but neuroscientists note that minimal brain activity can still occur undetected, and memories may be reconstructed after the fact as the brain "reboots."Dying might actually be a psychedelic experience. When the brain faces extreme stress, it releases a cocktail of DMT, endorphins, and dopamine while electrical hyperexcitation fires neurons en masse — creating vivid, dreamlike experiences that may explain the transcendent feelings people report.You don't need a near-death experience to live like you've had one. People who've had NDEs often return less materialistic, more focused on love, and at peace with mortality. The takeaway? You can adopt that perspective right now — prioritize connection over accumulation, presence over panic — without the terrifying trip to death's door.Connect with Jordan on Twitter, Instagram, and YouTube. If you have something you'd like us to tackle here on Skeptical Sunday, drop Jordan a line at jordan@jordanharbinger.com and let him know!Connect with Michael Regilio at Twitter, Instagram, Threads, Bluesky, and YouTube, and check out War Bar, his new comedy special!And if you're still game to support us, please leave a review here — even one sentence helps! Sign up for Six-Minute Networking — our free networking and relationship development mini course — at jordanharbinger.com/course!Subscribe to our once-a-week Wee Bit Wiser newsletter today and start filling your Wednesdays with wisdom!Do you even Reddit, bro? Join us at r/JordanHarbinger!This Episode Is Brought To You By Our Fine Sponsors: Northwest Registered Agent: Get more at northwestregisteredagent.com/jordanNutrafol: $10 off 1st month: nutrafol.com, code JORDANShopify: 3 months @ $1/month (select plans): shopify.com/jordanApretude: Learn more: Apretude.com or call 1-888-240-0340Homes.com: Find your home: homes.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Authentically ADHD
Your Brain Isn't Broken — It's Patterned (Understanding the AuDHD Brain)

Authentically ADHD

Play Episode Listen Later Dec 27, 2025 32:12


If you're AuDHD (autism + ADHD), life can feel like a constant contradiction: craving routine but rebelling against it, needing stimulation but getting overwhelmed, wanting connection but burning out socially. In this episode, Carmen breaks down what neurodivergence actually means (not a personality test), explains ADHD vs autism vs AuDHD, and gives practical, nervous-system-friendly strategies to build a life that fits your brain.Timestamped Chapters (approx)* 0:00 — Cold open: the AuDHD paradox in one breath* 1:30 — Neurodivergence: what it is (and what it isn't) Autistic Self Advocacy Network+1* 6:00 — ADHD explained: executive function + attention regulation CDC+1* 9:30 — Brain networks + “default mode interference” (why focus leaks) PMC+1* 11:30 — Autism explained: social communication + restricted/repetitive patterns CDC+1* 13:30 — Sensory processing differences + prediction models PMC+2PMC+2* 15:00 — AuDHD: why it's missed + DSM-5 history PMC+1* 18:00 — Co-occurrence and what it means (you're not “rare” or “weird”) PMC+1* 23:00 — The AuDHD Paradox Show: real-life examples* 32:00 — Tools & strategies: rails not cages, rotation menus, sensory-first, scripts* 39:30 — Closing: your brain is patterned + gentle next stepsKey Takeaways* Neurodiversity = natural variation in brains; neurodivergent is a nonmedical identity term. Autistic Self Advocacy Network+1* ADHD centers on executive functioning and attention regulation, not intelligence or effort. CDC+1* Autism centers on social communication differences + restricted/repetitive patterns, often including sensory differences. CDC+1* AuDHD can look contradictory because traits can mask each other; dual diagnosis became formally allowable in DSM-5. PMC+1* Sustainable support = “rails not cages,” rotation menus, sensory regulation, and externalizing executive function.Resources Mentioned* CDC: ADHD diagnosis overview CDC* CDC: ASD clinical diagnostic criteria overview CDC* ASAN neurodiversity explanation Autistic Self Advocacy Network* AuDHD comorbidity review (open access) PMCPredictive processing + prediction differences in autism (review/empirical)PMC+1SCRIPT:Hey there! Welcome or welcome back to another episode of authentically ADHD. I am not going to lie, this year has been hard and im so glad if you have stuck along with me, because the rest of the school year is going to be even busier. So thank you for your patience, and grace as I work through this year and let out episodes when I can. I had some inspo for this one because of the new year coming up, and ive talked about this before but not so much in depth. As I go through this episode, i want to share that ive recently self diagnosed myself as AuDHD, a person who has both ADHD and Autism. What does that mean? Well, lets talk about it!Okay, quick check-in: have you ever felt like your brain is two different people sharing one body— one who's like, “Please, for the love of God, routine. Predictability. Same mug. Same route. Same show on repeat.” and the other who's like, “If I do the same thing twice I will evaporate into dust like a vampire in daylight.”If yes… hi. Welcome. You're in the right place.Today's episode is called: “Your Brain Isn't Broken — It's Patterned.” Because I need you to hear this like it's a bass line in your chest:Your brain is not morally failing. Your brain is not lazy. Your brain is not “too much.”This Substack is reader-supported. To receive new posts and support my work, consider becoming a free or paid subscriber.Your brain is patterned. And if you're AuDHD—autism + ADHD—your pattern can feel like a paradox factory that runs 24/7 with no off switch and a slightly rude customer service department.So… let's talk about what neurodivergence actually is, how ADHD and autism overlap, where they differ, and why AuDHD can feel like living inside a contradiction—and then I'm gonna give you real strategies that don't feel like being yelled at by a productivity guru who thinks “just try harder” is a nervous system plan.[tiny pause]Are you ready? Let's get started.Substack adOkay, tiny intermission—because if this podcast is helping your brain feel a little more understood, I want you to know there's a whole extra layer of support waiting for you on my Substack.That's where I publish Authentically ADHD, and you can usually get the podcast there first—but it's not just a podcast drop. I've started writing blogs there too, which means you get deeper dives, the “ohhh THAT'S what's happening in my brain” explanations, plus practical tools you can actually use when your executive function is doing that thing where it simply… leaves the chat.And here's why I'm obsessed with it: Substack is neurodivergent-friendly by design. You can read posts when you want to skim, you can listen when reading is too much, and I include graphics most of the time because we deserve information in formats that don't require suffering.So here's your invitation: come subscribe on Substack. It's free to join, and if you decide to become a paid member, you'll get even more—bonus resources, extra content, and additional supports I'm building specifically for AuDHD/ADHD brains. Subscribe free… or go paid if you want the “director's cut” plus the toolbox. Either way, I'm really glad you're here.Neurodivergence: What it isSo lets talk about neurodivergence & how it is not a personality test. It's not “Which quirky brain are you?” It's not “I'm such an Aquarius so obviously I can't do laundry.”And I say that as a person who loves a good identity moment.Neurodiversity is the idea that human brains vary—like biodiversity, but for minds. There isn't one “correct” way a brain must work to be worthy. Neurodivergent is a non-medical term people use when their brain develops or functions differently from what society calls “typical.”Now—this matters— Saying “it's a difference” does not erase disability. Some people are deeply disabled by ADHD or autism. Some need significant supports. Some don't. Many fluctuate across seasons of life. But the point is: difference isn't the same thing as defect.A patterned brain can be brilliant and still struggle. Because a lot of suffering isn't just “the brain,” it's the brain + the environment.If the world is built for one nervous system style, and you're running a different operating system, you're going to feel like you're constantly doing life on hard mode.[pause]And if you've spent your whole life trying to “fix” yourself into the version of you that makes other people comfortable— I just want to say: I see you. That's exhausting. That's not personal weakness. That's chronic mismatch.6:00–15:00 — ADHD vs Autism: Overlap and differences (clear, non-weird)Let's do ADHD vs autism without turning it into a simplistic “either/or” checklist, because real humans are not BuzzFeed quizzes.ADHD (core pattern)ADHD is a neurodevelopmental condition where the core struggles involve attention regulation, impulsivity, and executive functioning—planning, starting, stopping, shifting, organizing, time sense, working memory… the invisible stuff that makes life run. Important: ADHD is not “can't pay attention.” It's can't consistently regulate attention—especially when bored, stressed, overwhelmed, under-stimulated, or over-stimulated.One research-heavy way people talk about ADHD is the “default mode interference” idea—basically, brain networks involved in internal thought can intrude when you're trying to stay on task. It's not the only model, but it helps explain why focus can feel like trying to hold water in your hands.Real-life ADHD examples:* You can focus for hours on something you care about… and cannot start the thing you care about that also feels hard.* You lose time like it's a hobby.* You forget what you're doing while you're doing it.* You can be highly intelligent and still struggle with basic tasks because executive function isn't IQAutism (core pattern)Autism is also neurodevelopmental. Clinically, it involves:* differences in social communication and interaction across contexts* and restricted/repetitive patterns (routines, sameness, focused interests, stimming, etc.) Also—and this is big—many autistic people experience sensory processing differences: the world can be too loud, too bright, too unpredictable… or sometimes not enough and you seek sensation.Researchers also explore prediction-based models—how the brain learns patterns and predicts what's next, and how differences in prediction/updating may relate to autistic experience. It's nuanced (and not every study supports every claim), but it's a helpful lens for why uncertainty can feel physically stressful.Real-life autism examples:* Social rules can feel like invisible ink.* You may crave clarity and directness and feel drained by ambiguity.* Transitions can hit like a wall.* You might have deep, intense interests that feel regulating and grounding. So then, hers the overlap, why it's confusing. ADHD and autism can both include:* sensory sensitivity* emotional overwhelm* social exhaustion* executive dysfunction* hyperfocus* stimming/fidgeting* burnoutSo yes, overlap is real. Which brings us to the main character of today's episode…Patreon & focused adAuDHD: The overlap, the “double bind,” and why it's missedAuDHD is shorthand for being both autistic and ADHD. It's not a separate DSM diagnosis label, but it's a very real lived experience.And historically, here's why many adults didn't get recognized: Before DSM-5 (2013), autism could prevent someone from also being diagnosed with ADHD—even though many people clearly had both. DSM-5 changed that, acknowledging the reality of co-occurrence. PMC+1Co-occurrence is common enough that researchers and clinicians have been studying it heavily; some reviews discuss high overlap rates (numbers vary by study and method), but the key point is: this isn't rare. PMC+1Now the AuDHD “double bind” can look like:* ADHD traits can mask autism traits (you seem spontaneous and social… until you crash).* Autism traits can mask ADHD traits (you seem organized because you built rigid systems… until the system breaks and chaos floods the house).* You can be sensory avoidant and sensory seeking.* You can crave routine and crave novelty.AuDHD often feels like living in a brain that says:“I need sameness.” “I need dopamine.” “I need quiet.” “I need stimulation.” “I need certainty.” “I need freedom.”…and they're all yelling at once. [small laugh]So when people say, “But you don't seem autistic,” or “You don't seem ADHD,” sometimes what they're actually noticing is: your traits are playing tug-of-war.23:00–32:00 — The AuDHD Paradox Show (real-life examples)Paradox #1: Routine vs noveltyAutism: “Same breakfast. Same spoon.” ADHD: “If I eat the same breakfast again I will emotionally file for divorce.”Real life: You create the perfect morning routine. It works for four days. On day five your brain wakes up and goes: “Actually, we hate that now.”Not because you're flaky. Because the need for predictability and the need for stimulation are both legitimate.Paradox #2: Social craving vs social costADHD can crave social stimulation. Autism can find social processing costly.Real life: You make plans and feel excited. Then the day arrives and your body feels like you're trying to attend a party wearing jeans made of sandpaper.So you cancel, then feel guilty, then feel lonely, then feel annoyed that humans require maintenance. [pause] Relatable.Paradox #3: Sensory seeking vs sensory painReal life: Loud music helps you focus… until one more sound happens and suddenly you're like, “I live in a cave now.”You can want pressure and weight and deep sensory input while also being destroyed by light touch or fluorescent lights.Paradox #4: Hyperfocus vs shutdownReal life: You can research a niche topic for six hours and forget you have a body… but you cannot reply to a two-sentence text.Because replying requires:* context switching* social interpretation* decision making* emotional energy* working memoryAnd your brain is like, “That's 12 tasks. No thanks.”Paradox #5: Justice sensitivity + impulsivityReal life: You notice something unfair. Your body becomes a courtroom. ADHD makes you say it immediately. Autism makes you say it precisely. And suddenly everyone is uncomfortable and you're like, “What? I brought facts.”Paradox #6: The “I'm fine” lieA lot of AuDHD adults become world-class at looking “fine.” Not because it's fine—because it's practiced.Real life: You hold it together all day. Then you get home and collapse like a puppet whose strings got cut.That is not you being dramatic. That is nervous system math.Strategies: “Rails not cages” + tools that actually workAlright. Let's talk tools—AuDHD-friendly, reality-based, and not built on shame.Rule #1: Build rails, not cagesA cage is a rigid routine that breaks the second you miss a step. Rails are guiding tracks that keep you moving even on messy days.Do this: Create three anchors, not a full schedule.* Anchor 1: Start — water + meds + protein OR any “first 5 minutes” ritual* Anchor 2: Midday reset — sensory check + movement + hydration* Anchor 3: Land — dim lights + predictable wind-down cueIf you miss an anchor, you don't throw away the day. You grab the next rail.Rule #2: Rotate instead of “routine”AuDHD often needs predictability in category and novelty in options.So instead of one rigid breakfast, do a Breakfast Rotation Menu:* 5 safe breakfasts* 3 “no-cook” defaults* 2 “my brain is fried” emergency optionsSame for outfits. Same for playlists. Same for chores.It's not indecision. It's accommodating the paradox.Rule #3: Sensory first, then strategyIf your nervous system is in siren mode, no planner hack will work.2-minute reset:* change input: step away / dim light / earplugs* add steady sensation: pressure, cold sip, gum, textured object* long exhale (longer out than in)You're not “calming down.” You're changing states.Rule #4: Externalize executive function (because willpower isn't storage)Executive function can tank under stress in ADHD and autism. So stop trying to “remember harder.”Externalize:* visual timers* one-step checklists* “landing pads” (keys, meds, bag)* pre-decisions (“If it's Tuesday, I do X”)If it has to live only in your head, it will get evicted.Rule #5: Transition protocol (gentle, not militant)Transitions can be brutal because they require stopping, switching, sensory changes, and decision-making.5-minute bridge:* “Close” the old task: write one sentence: “Next I start by ____.”* body bridge: stand, water, stretch* 2-minute micro-start on the new task (so it's not a cliff)Rule #6: Scripts are accessibility toolsScripts aren't fake. They're scaffolding.Steal these:* “I want to, but my brain can't today. Can we reschedule?”* “What's the plan and how long are we staying?”* “I'm going quiet to regulate, not because I'm mad.”* “I need a minute to process before I answer.”Rule #7: Stop treating burnout like a personal failureBurnout often comes from masking, chronic mismatch, sensory load, and executive demand. You don't fix burnout with hustle. You fix it with less demand and more support.Quick audit:* What drains me that I keep calling “normal”?* Where am I denying myself accommodations because I want to look “easy”?* What would sustainability look like—literally, this week?So here's what I want you to take with you:Your brain isn't broken. It's patterned. And patterned brains don't need shame. They need fit. They need support. They need design.If this episode hit you in the chest a little—breathe. You're not behind. You're not defective. You're learning your pattern. And that's not a small thing. That's a homecoming.If you want, share this episode with the friend who keeps calling themselves “too much.”And if you're new here—welcome. You're safe. You're seen.And as always: this is educational, not medical advice. If you're seeking diagnosis or support, a qualified clinician can help you sort what's AuDHD and what's trauma, anxiety, sleep, hormones, or burnout wearing a trench coat. Until nextt time, stay authentic my friend, & we will talk soon.SubStack Page: Get full access to carmen_authenticallyadhd at carmenauthenticallyadhd.substack.com/subscribe

Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Antihypertensives Test Prep and Practice Pearls; Part 3 – Aldosterone Antagonists and Vasodilators

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Play Episode Listen Later Dec 25, 2025 14:28


Aldosterone antagonists, such as spironolactone and eplerenone, are potassium-sparing diuretics that block aldosterone at the mineralocorticoid receptor in the distal nephron. By reducing sodium and water reabsorption while conserving potassium, they play a key role in heart failure, resistant hypertension, and primary hyperaldosteronism. Clinically, they improve mortality in heart failure with reduced ejection fraction, making them much more than just “add-on” diuretics. From a safety standpoint, the biggest concerns with aldosterone antagonists are hyperkalemia and renal function decline. These risks increase in patients with chronic kidney disease or when combined with ACE inhibitors, ARBs, or potassium supplements. Spironolactone can also cause endocrine-related adverse effects such as gynecomastia and menstrual irregularities, which is why eplerenone may be preferred in some patients. Direct-acting vasodilators, most notably hydralazine and minoxidil, lower blood pressure by relaxing arteriolar smooth muscle and reducing systemic vascular resistance. Hydralazine is commonly used in heart failure in combination with nitrates, particularly in select patient populations, while minoxidil is reserved for severe, refractory hypertension due to its potency. Despite their effectiveness, direct-acting vasodilators come with important clinical trade-offs. Reflex tachycardia and fluid retention are common, so they are typically prescribed alongside a beta blocker and a diuretic. Hydralazine is associated with drug-induced lupus, while minoxidil can cause significant edema and hypertrichosis, making careful patient selection and monitoring essential. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources! NAPLEX Study Materials BCPS Study Materials BCACP Study Materials BCGP Study Materials BCMTMS Study Materials Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101

HINESIGHTS Podcast
The Avengers Of Suicide Loss | Clinically Related | Hinesights Podcast | Clips

HINESIGHTS Podcast

Play Episode Listen Later Dec 23, 2025 1:48


The Avengers Of Suicide Loss | Clinically Related | Hinesights Podcast | Clips

Rehab Science with Tom Walters
SLAP Tears of the Shoulder: What They Are and How They're Treated

Rehab Science with Tom Walters

Play Episode Listen Later Dec 22, 2025 10:46


SLAP tears refer to injuries of the superior labrum of the shoulder, where the long head of the biceps tendon attaches to the glenoid. These tears are commonly identified on imaging, particularly in overhead athletes and aging populations, but their presence does not always explain pain or dysfunction. The shoulder relies heavily on soft tissue structures for stability, and the biceps–labral complex is exposed to significant load during overhead and deceleration activities. Importantly, labral changes are frequently seen in asymptomatic individuals, highlighting that structural findings alone do not equate to symptoms. Clinically, SLAP tears may present with deep shoulder pain, discomfort during overhead activity, clicking sensations, or fatigue with repeated use, though symptoms often overlap with other shoulder conditions. Diagnosis is challenging, as no single clinical test is highly accurate and imaging frequently reveals incidental findings. Meaningful diagnosis requires correlating symptoms, functional limitations, and activity demands rather than relying on imaging alone. From a treatment standpoint, conservative management is the first-line approach for most individuals. Rehabilitation focuses on restoring shoulder strength, scapular control, and load tolerance rather than "fixing" the labrum itself. While surgery may be appropriate in select cases, many people experience meaningful improvement with well-structured physical therapy. This episode explores how education, progressive loading, and evidence-based rehab strategies can help individuals return to function, even in the presence of a diagnosed SLAP tear. Link for my book: https://amzn.to/3Ld7ssd Link for my app: https://rehabscience.com/membership/ YouTube SLAP rehab video: https://youtu.be/FwiDJ6hoaYo?si=924NiLBuqPxBri0g  

Zo Williams: Voice of Reason
What's Mine is MINE and What's Yours is YOURS

Zo Williams: Voice of Reason

Play Episode Listen Later Dec 17, 2025 75:02 Transcription Available


Most people believe emotions happen to them. Clinically speaking, they do not. Emotions arise within the nervous system, shaped by history, attachment, memory, and interpretation. The moment a person treats emotion as something caused by another, authority transfers. That transfer appoints an emotional gatekeeper. This distinction matters because intimacy collapses the moment emotional authority leaves the self. Emotional accountability requires presence. It means staying with bodily sensation, affect, and interpretation long enough to identify one's role in the interaction without collapsing into defense, blame, or self-erasure. Accountability does not ask who caused the feeling. It asks what arose internally and why. This process restores authorship over one's emotional state.

Zo Williams: Voice of Reason
What's Mine is MINE and What's Yours is YOURS

Zo Williams: Voice of Reason

Play Episode Listen Later Dec 17, 2025 75:50


Most people believe emotions happen to them. Clinically speaking, they do not. Emotions arise within the nervous system, shaped by history, attachment, memory, and interpretation. The moment a person treats emotion as something caused by another, authority transfers. That transfer appoints an emotional gatekeeper. This distinction matters because intimacy collapses the moment emotional authority leaves the self. Emotional accountability requires presence. It means staying with bodily sensation, affect, and interpretation long enough to identify one's role in the interaction without collapsing into defense, blame, or self-erasure. Accountability does not ask who caused the feeling. It asks what arose internally and why. This process restores authorship over one's emotional state.

ASCP Esty Talk
Ep 366 – Too Early for Beauty Rituals?

ASCP Esty Talk

Play Episode Listen Later Dec 17, 2025 13:47


Skin care for 4-year-olds? It's the beauty debate that just won't die. Conversations about children and skin care continue to resurface in the media and on social media, and estheticians everywhere have their thoughts about it. In this episode of ASCP Esty Talk, Maggie and Ella break down the controversy, share their own opinions, and compare today's kid "wellness rituals" with the play makeup, glitter gloss, and press-on nails of their own childhoods. ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   Comfort Zone – The Italian, multi-awarded science-led, longevity-focused skincare trusted by professionals worldwide. Founded by Dr Bollati, a pharmacist, and powered by over 60 in-house chemists and skin care experts. Clinically tested formulations blend clinical precision, regenerative botanicals, and biotechnology research to transform skin with intention. Part of The Davines Group, certified B Corp since 2016.   Website: https://us.comfortzoneskin.com/   Instagram: https://www.instagram.com/comfortzoneskin_official/   Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare   

Generations M.D.
NOT CLINICALLY RELEVANT!

Generations M.D.

Play Episode Listen Later Dec 17, 2025 30:27


Today, stephanie and dr. davis talk about step 1 and how many things in medical education are not clinically relevant.

Near Death Experience
PROOF OF THE AFTERLIFE: What Happens When You're Clinically Dead? (True NDE Story)

Near Death Experience

Play Episode Listen Later Dec 17, 2025 118:41 Transcription Available


This episode features a powerful and verified account of a True Near Death Experience (NDE). What happens when you are Clinically Dead? Our guest shares their astonishing journey after their heart stopped—a profound Out-of-Body Experience (OBE) where they observed doctors working on their physical body. They died and then received verifiable Proof of the Afterlife, including a transformative Life Review and an encounter with the Being of Light. This is an essential listen for anyone seeking evidence of Consciousness After Death and understanding what really happens in the moments between life and death.

On Becoming a Healer
Poems about the wretched illness experience when your doctor is"clinically detached"

On Becoming a Healer

Play Episode Listen Later Dec 16, 2025 50:00


Writing about the illness experience, medical sociologist Richard Frank described an unspoken agreement with his doctor that if he adopted their detached and clinical language when discussing his illness, "I would have at least a junior place on the management team." Initially it seemed like "not a bad deal," until he experienced the toll it took, concluding that, "No one should have to stay cool and professional while being told their body is breaking down, though medical patients always have to do just that."  Through three poems selected by our repeat guest, English professor Laura Greene of Augustana College, we see the pain and cost to patients when their doctors and nurses hold them at arm's length, unable or unwilling to see their humanity. We reflect on why, and what to do about it. 

ASCP Esty Talk
Ep 364 – Should It Stay or Should It Go—2025 Beauty and Wellness Trends

ASCP Esty Talk

Play Episode Listen Later Dec 10, 2025 15:08


It's that time of year when we start thinking ahead, so Ella and Maggie are kicking off their annual look at the trends shaping the next season of skin, style, and self-care. In this episode of ASCP Esty Talk, they play a rapid-fire game of "Should It Stay or Should It Go?", weighing in on 2025's most buzzworthy beauty and lifestyle trends. From barrel jeans and skinimalism to tattooed freckles, laminated brows and facial scrubs—nothing is off-limits. ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   Comfort Zone – The Italian, multi-awarded science-led, longevity-focused skincare trusted by professionals worldwide. Founded by Dr Bollati, a pharmacist, and powered by over 60 in-house chemists and skin care experts. Clinically tested formulations blend clinical precision, regenerative botanicals, and biotechnology research to transform skin with intention. Part of The Davines Group, certified B Corp since 2016.   Website: https://us.comfortzoneskin.com/   Instagram: https://www.instagram.com/comfortzoneskin_official/   Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare   

The Dental Hacks Podcast
Very Dental Student: Mo on Boards and Externships!

The Dental Hacks Podcast

Play Episode Listen Later Dec 8, 2025 40:02


In this episode of the Very Dental Student Podcast, host Mohamed Abo-Basha and Dr. Alan Mead discuss his journey through the fall semester of his D4 year. We discuss Mo's recent experiences with dental boards and externships as he approaches graduation. Mo shares that the dental boards have recently changed, moving away from live patient exams to mannequin-based clinical testing (Prosthodontics, Endodontics, Periodontics already completed, Operative to follow) and computer-based written boards. He expresses that this change is a positive step ethically. Clinically, Mo is nearing completion of his requirements, only needing a few more Scaling and Root Planing (SRP) cases. He also details his externships, which provided valuable experience in high-volume operative and extraction procedures at a low-fee clinic and a mobile unit, significantly boosting his speed and confidence in procedures like administering anesthesia and performing quick, effective patient exams. Looking ahead, his final semester will primarily involve a Surgical Implantology class and serving as a Teaching Assistant (TA) for first-year operative students, which he anticipates will be a rewarding experience. Join the Very Dental Facebook Group using one of these passwords: Timmerman, Bioclear, Hornbrook, Gary, McWethy, Papa Randy, or Lipscomb! The Very Dental Podcast Network is and will remain free; please support the people who support us! Crazy Dental has everything you need—from cotton rolls to equipment—at the best prices! Get an free shipping on your order by visiting verydentalpodcast.com/crazy and using coupon code VERYSHIP. Save money and support the show. The Wonderist Agency is your one-stop shop for marketing your dental practice and brand. They cover everything from logo redesign to a full-service marketing plan. Check them out at verydentalpodcast.com/wonderist Enova Illumination makes the very best in loupes and headlights, including their new ergonomic angled prism loupes. They also distribute loupe-mounted cameras and Zumax microscopes! Boost your magnification/headlight game and support the podcast at verydentalpodcast.com/enova. CAD-Ray offers the best service on a wide variety of digital scanners, printers, mills, and their own browser-based design software, Clinux. See the brand new scanner from Shining 3D, the Elf! Get the best service on all things digital dentistry at verydentalpodcast.com/CADRay!

Hip Creative
Why Patient Experience TRUMPS Technology in Orthodontics

Hip Creative

Play Episode Listen Later Dec 8, 2025


Orthodontists pour millions into technology, systems, and clinical training. Those investments matter. But zoom out and look at which practices actually grow year over year. The differentiator is not the scanner, the wire sequence, or the aligner system. The practices that grow treat patients like people, not procedures. In a world full of convenience, automation, and self-checkout everything, genuine human experience has become the rarest competitive advantage in orthodontics. At HIP, we have seen it across hundreds of practices: when your team becomes truly patient centric, your results follow. This is not a nice-to-have. It is the engine behind case acceptance, referrals, and retention. Here is what that actually means and how you build it. The Emotional Side of Orthodontics Orthodontic treatment is not just a mechanical process. Patients carry their smile into every room they walk into for the rest of their lives. Confidence. Insecurity. Pride. Avoidance. Whether someone feels free or guarded, their orthodontic journey shapes all of that. Forget the emotional stakes and you lose the patient. Every interaction with your practice either reinforces their confidence or feeds their fear. In today’s world, where everything is automated and transactional, that emotional experience matters more than ever. Patients expect clinical excellence. They remember how your team made them feel. That feeling brings them back and keeps them talking about you. Technology Does Not Differentiate You. Experience Does. A lot of practices believe their growth will come from their scanner, their bracket system, their aligner protocols, their dashboard, their workflow. Technology matters. It supports efficiency. It shortens treatment times. It allows for predictable outcomes. But patients cannot tell you the difference between wire systems. They have no idea what your software does. They can tell you if your front desk greeted them warmly. They can tell you if your space felt clean and inviting. They can tell you if they felt remembered or forgotten. The truth is simple: technology creates capability, patient experience creates loyalty. Free Growth Session First Impressions — The Moment That Sets the Tone For Everything Before a patient ever sees a TC, an assistant, or the doctor, they are already forming their opinion. They are evaluating whether they feel safe. They are reading whether your team is present or overwhelmed. They are noticing whether they are interrupting you or welcomed. A great first impression includes clear signage and easy navigation so patients know where to go, a clean and bright environment that signals professionalism without feeling sterile, a genuine greeting that acknowledges them immediately, and eye contact plus warmth so they feel seen instead of processed. If this first moment goes sideways, you have already lost ground. If it goes well, everything else becomes easier. The TC Room — Where Trust Is Formed Or Lost The treatment coordinator room is the most pivotal space in the practice. It is where excitement becomes commitment or where uncertainty grows into hesitation. Practices that win in this room keep the handoff tight, smooth, and confident. They remove the left-alone-in-silence moments that create anxiety. They treat the patient as the hero of the story, not the object of a procedure. They engage on a human level before diving into clinical detail. When patients feel known instead of managed, they say yes more often and they stay excited throughout treatment. Free Growth Session Mid-Treatment Visits — The Overlooked Opportunity This is where many practices unintentionally lose the patient experience altogether. Routine appointments easily slide into autopilot. The assistant has done this exact wire change ten times today. The patient knows the drill. Everyone falls into the rhythm. That is the danger. A patient who feels invisible mid-treatment becomes disengaged. They stop wearing rubber bands. They lose excitement. They feel like a number. The practices that maintain loyalty during routine visits do one thing consistently: they never stop seeing the patient. That means personalized notes that allow any assistant to pick up the conversation, asking about the football game or the prom or the test or the birthday or the struggle, staying energetic even in routine appointments, and celebrating small steps toward the end result. Efficiency does not cost empathy. Efficiency creates space for empathy. Retention — The Most Undervalued Stage Of The Entire Journey Many offices treat retention like the checkout lane. Here are your retainers, congrats, call us if something breaks. Retention is where practices lose referrals and where they could be gaining them. Retention works best when the team celebrates the finish line with real enthusiasm, when debond day is treated like a milestone worth cheering for, when the patient leaves feeling proud of what they accomplished, when the team makes the experience fun and memorable and personal, and when you reinforce why wearing retainers matters without guilt or shame. When the final memory is a great one, patients become raving fans. And when they inevitably need retreatment years down the road, they come back to the place that made them feel cared for, not the cheapest or closest option. Free Growth Session Why This Matters — The Human Challenge Your team is human. They get tired. They get overwhelmed. They deal with difficult patients. They have personal stress. When they are stretched thin, the first thing to disappear is the patient experience. That is why the culture has to carry the weight, not individual moods. A consistent patient experience comes from clear standards, strong systems, personal accountability, team cohesion, morning huddles that reinforce connection, and leadership that models presence and empathy. This is not about perfection. It is about direction. A one percent improvement every day builds a culture that becomes unstoppable. The Practices That Win Care The Most At HIP, we say it often: you do not build a great practice by focusing on teeth. You build it by focusing on people. Clinically excellent orthodontists are everywhere. Patient-centric teams are rare. The practices that become market leaders are not the ones with the newest tech or the flashiest marketing. They are the ones patients talk about long after the appointment is over because the experience made them feel something real. If you want to grow, improve your systems, and elevate your team, start with the one thing your competitors cannot copy: the way you make people feel when they walk through your door. Do that consistently and your practice becomes unforgettable. Free Growth Session The post Why Patient Experience TRUMPS Technology in Orthodontics appeared first on HIP Creative.

ASCP Esty Talk
Ep 363 – Freakiest Friday

ASCP Esty Talk

Play Episode Listen Later Dec 3, 2025 14:32


In this episode of ASCP Esty Talk, Ella and Maggie explore the difference between routine and ritual—and why it matters in self-care. Most of us go through the motions of skin care and wellness without truly being present, but when we shift from task to intention, even the simplest steps become transformative. To put this idea into practice, Ella and Maggie swap skin care rituals—each assigning one for the other that blends breathwork, visualization, affirmation, and a healthy dose of humor. The result is a conversation that's both grounding and giggleworthy, reminding us that real self-care isn't just what you do, it's how you do it. ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   Comfort Zone – The Italian, multi-awarded science-led, longevity-focused skincare trusted by professionals worldwide. Founded by Dr Bollati, a pharmacist, and powered by over 60 in-house chemists and skin care experts. Clinically tested formulations blend clinical precision, regenerative botanicals, and biotechnology research to transform skin with intention. Part of The Davines Group, certified B Corp since 2016.   Website: https://us.comfortzoneskin.com/   Instagram: https://www.instagram.com/comfortzoneskin_official/   Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare   

The Self Esteem and Confidence Mindset
Clinically Dead and Back: A Near-Death Experience That Changed Everything with Steve Brown

The Self Esteem and Confidence Mindset

Play Episode Listen Later Nov 28, 2025 36:19


What happens when you die—and come back? In this profound and life-changing episode of The Self Esteem and Confidence Mindset, we sit down with Steve Brown who shares his incredible story of being clinically dead, experiencing the other side, and returning to life with a completely transformed perspective on purpose, fear, and what truly matters.Steve's near-death experience (NDE) is not just a story of survival—it's a powerful lesson about overcoming fear of death, living without regret, finding your life purpose, and building unshakeable confidence when you understand how precious and temporary life really is.In this episode, you'll discover:Steve's incredible story of being clinically dead and what he experiencedWhat happens during a near-death experience and the profound lessons it teachesHow facing death transformed Steve's fear, anxiety, and perspective on lifeWhy most people live in fear and how a brush with death brings clarity and courageThe life-changing insights about purpose, meaning, and what really mattersHow to live with confidence and intention when you understand life's fragilitySteve's journey of recovery, resilience, and rebuilding after a life-altering experienceOvercoming PTSD, trauma, and the emotional aftermath of surviving deathHow to stop wasting time on what doesn't matter and focus on what doesThe spiritual awakening and personal transformation that comes from near-death experiencesThis conversation will challenge everything you think you know about life, death, fear, and purpose. If you've been living on autopilot, afraid to take risks, or wondering what your life is really about, Steve's story will inspire you to wake up and live fully.Grab Steve latest book here:⁠https://www.amazon.ca/Are-Ready-Call-Stephen-Brown/dp/B0FRQFH1KG⁠

Wednesday Night Podcast
James Brown Hot

Wednesday Night Podcast

Play Episode Listen Later Nov 26, 2025 51:05


Send us a textThis week on The Wednesday Night Podcast, we're bringing the heat! James Brown is on the turntable, and we're spinning his smokin' album, Hot, as the soundtrack for our annual (and entirely seasonally confused) Thanksgiving Spooktacular! Forget gravy and stuffing—we're serving up sweet agony.We're testing the panel's mettle with a truly punishing Classic Rock Knowledge Quiz. The quiz starts with easy-listening hits (Queen basics) but quickly escalates into deep-cut, obscure territory (hello, yacht rock trivia and questionable 70s B-sides). The goal is simple: answer correctly, or face the heat!The prize for failure? A spoonful of creamy vanilla ice cream... topped with a generous dash of hot sauce. Here's the catch: the more rock history questions our hosts miss, the hotter the sauce gets! We're escalating the pain in four brutal levels:Level 1 (Mild Regret): Think simple Tabasco or mild cayenne pepper. Easy, but embarrassing.Level 3 (Serious Sweat): We jump to ghost pepper blends. Tears may be shed.Level 5 (Total Disaster): The Last Dab—sauces featuring Apollo Peppers. Clinically certified regret.Find out whose mouth is literally on fire by the end of the episode. Tune in to hear the Godfather of Soul provide the perfect backing track to a symphony of coughing, crying, and desperate pleas for cold dairy products.website: actonmusicproject.comemail: music@actonmusicproject.comCraig's phone number: ‪(978) 310-1613‬

Inspire Change with Gunter
Inspire Change Season 7-310 A Conversation with Greg Downey

Inspire Change with Gunter

Play Episode Listen Later Nov 26, 2025 69:53 Transcription Available


This week on Inspire Change...In this engaging conversation, Gunter Swoboda and Greg Downey, renowned Anthropologist, explore the complexities of masculinity, touching on its evolution, the impact of toxic ideologies, and the importance of emotional health. They discuss the intersection of masculinity with community, politics, and religion, emphasizing the need for a nuanced understanding of men's issues. The dialogue highlights the role of anthropology in providing insights into masculinity and the importance of fostering connections and understanding in addressing these challenges. ChaptersIntroduction to the ConversationShifts in Understanding MasculinityComplexities of Male Violence and VictimhoodToxic Ideologies of MasculinityPsychological Impacts of MasculinityIndividualization in Masculinity DiscussionsNavigating Politics and Religion in MasculinityApolitical Perspectives on Gender and HumanityThe Role of Religion in Community and Morality38:26 Navigating Autocracy and Religious InfluenceMasculinity and Emotional ResponsivenessSomatic Psychotherapy and Emotional AwarenessAggression vs. Assertiveness in Male BehaviorAnthropology's Role in Understanding Human BehaviorTakeawaysMasculinity is embodied and practiced, not just theoretical.The concept of moral injury is crucial in understanding veterans' experiences.The men's movement has evolved, but some ideas remain problematic.Social media influences perceptions of masculinity, often negatively.Understanding domestic violence requires a nuanced view of perpetrators and victims.Toxic ideologies harm both men and women in society.Emotional dysregulation in men is linked to societal expectations.Community and spirituality can provide support for men.The intersection of politics and masculinity complicates discussions.Anthropology can offer valuable insights into the complexities of masculinity.Mid-Episode Break is brought to you by our new sponsor Distil Union.“You know, on this show we talk a lot about living with purpose — slowing down, paying attention, and being intentional about the choices we make every day. Because when we simplify the noise around us, we can better hear what really matters: empathy, connection, and showing up as the best version of ourselves. That's why I'm genuinely pleased to welcome our newest sponsor, Distil Union. Their philosophy aligns beautifully with what we do here.”  “Distil Union creates sleek, thoughtfully designed essentials — wallets, key organizers, phone cases — all built with a ‘less is more' approach. Their Wally wallets, Ferris key organizers… these are everyday tools that make life easier, cleaner, and calmer. And in that simplicity, there's space for clarity. There's space for change.” “As a thank-you to our Inspire Change community, they're offering 20% off any product with the promo code INSPIRECHANGE. Have a look, try them out, and see how simplifying your day can open the door to something deeper.” Visit distilunion.com and enjoy 20% off any product with promo code INSPIRECHANGE. That's distilunion.com with promo code INSPIRECHANGE at check out.”End Sponsor-Break at MoreLabs:So it's that time of the year again! Yes, you heard me, THE HOLIDAYS are fast approaching and we all know what that means…parties, gatherings, work and business socials.  Science has evolved and there is no reason to waste time trying to recover from a night of celebrating. You may know what I mean if you have EVER had a few too many, that dreaded next morning where your head is pounding and you can't fathom the thought of getting up to use the rest room. Horrible! That's why we  believe in the scientific triumph that is Morning Recovery. It's scientifically formulated to help you bounce back after a night of drinking. It's made with ingredients like Milk Thistle and ginseng to help you recover from last night's festivities. Plus it's loaded with electrolytes and B Vitamins that replenish lost nutrients. It is seriously a game changer, your new “drink one before having a good time”, and wake up ready for anything drink!  More Labs' Morning Recovery is the #1 alcohol recovery supplement that helps you wake up clear-headed and refreshed. Clinically proven and trusted by thousands, with 20M+ bottles sold and a 4.9-star rating, it works. Try it risk-free! Enjoy an exclusive discount with our promo code https://www.morelabs.com/discount/INSPIRECHANGE Our code will be applied to your cart and you get a discount at any of the products at MoreLabs.com Their products are loaded with super ingredients—Milk Thistle, Prickly Pear, Red Ginseng, Electrolytes, and B Vitamins. It is Developed with top scientists—including Dr. Fu Chen, a former FDA expert in supplement absorption. MoreLabs products work better than sports drinks—targets toxin buildup and nutrient loss, not just dehydration. Their products are a clean formula—no artificial colors, sweeteners, or preservatives.  It is also portable & TSA-friendly—perfect for travel, work, or big nights out.GRATITUDE MENTIONS & CLOSING -Hello to all our listeners, we thank YOU for tuning in and promoting positive social change.  This makes you a part of Gunter's efforts in transforming not only men's lives but lives in general and we are grateful you have joined us. This week we are taking a look at the Global Listeners List and we would like to share our gratitude with our listeners in the UK. You made it to #3 on our Global Listeners List! And a special shout out to London, Cambridge, Camden, and & Lambeth as well as Falkirk, Scotland for being the top listeners within the UK! CONGRATULATIONS!!!We thank you so much for your continued support and we appreciate your efforts to support positive social change! I, DeVonna Prinzi the Co-Exec Producer and our Show-runner Miranda Spigener-Sapon sincerely thank you and ask that you please take the time to like, follow, subscribe, and share as your efforts make a difference to everyone here at Inspire Change with Gunter.Please remember If you want to share your story of social change, feel free to reach out  to the show directly. Please see the show-notes for our contact information.  As always thank you to each and every one of our listeners, and most importantly please keep Inspiring positive social change.Become a supporter of this podcast: https://www.spreaker.com/podcast/inspire-change-with-gunter--3633478/support.Gunter Swoboda and Lorin Josephson's neo-noir/supernatural thriller novel Amulets of Power, Book I A Brian Poole Mystery is officially ON SALE EVERYWHERE you like to get book, but if you want a discount please consider ording direct. ANY LISTENER who order's direct will get a surprise gift. https://shop.ingramspark.com/b/084?params=3RoOA6kVQ7ZgmqSK9LdnvNyDAZZFsg9IMaLUaprPgXKMake sure you LIKE SUBSCRIBE & FOLLOW our new Official YouTube Channel of Video Shorts series: https://www.youtube.com/@InspireChangewithGunterSwoboda/videos where we will be adding new videos and content every week from Gunter and our guests.  https://www.youtube.com/@InspireChangewithGunterSwoboda/videos

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Glycopyrrolate is an anticholinergic medication commonly used to reduce excessive secretions, particularly in palliative care, postoperative settings, and certain neurologic conditions. It works by blocking acetylcholine at muscarinic receptors, which decreases salivary and respiratory secretions. Clinically, glycopyrrolate is often used to manage terminal respiratory secretions (“death rattle”). Adverse effects of glycopyrrolate are primarily related to its anticholinergic properties. These may include dry mouth, constipation, urinary retention, blurred vision, tachycardia, and decreased sweating. While it has fewer central effects than agents like scopolamine, caution is still warranted in patients with glaucoma, gastrointestinal obstruction, or significant urinary retention risk. Monitoring hydration and bowel function is important, especially in elderly or frail patients. Dosing strategies depend on the clinical need. In palliative care, low doses may be given subcutaneously or intravenously every 4–6 hours as needed, while oral dosing is common for chronic sialorrhea. Clinicians should consider the patient's overall medication burden, as cumulative anticholinergic load can worsen cognitive impairment and contribute to falls or constipation. I discuss drug interactions and other commonly used medications that may contribute to anticholinergic burden.

Darkest Mysteries Online - The Strange and Unusual Podcast 2023
People who have been clinically dead and came back, how was the other side like

Darkest Mysteries Online - The Strange and Unusual Podcast 2023

Play Episode Listen Later Nov 20, 2025 59:56


People who have been clinically dead and came back, how was the other side likeBecome a supporter of this podcast: https://www.spreaker.com/podcast/darkest-mysteries-online-the-strange-and-unusual-podcast-2025--5684156/support.Darkest Mysteries Online

ASCP Esty Talk
Ep 361 - Guilty Pleasures: Food and Skin Health

ASCP Esty Talk

Play Episode Listen Later Nov 19, 2025 16:56


Are wine, cheese, and chocolate really sabotaging your glow—or is it time to stop feeling guilty about what's on your plate? In this episode, Maggie and Ella break down food myths, facts, and what really matters for healthy skin. ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   Comfort Zone – The Italian, multi-awarded science-led, longevity-focused skincare trusted by professionals worldwide. Founded by Dr Bollati, a pharmacist, and powered by over 60 in-house chemists and skin care experts. Clinically tested formulations blend clinical precision, regenerative botanicals, and biotechnology research to transform skin with intention. Part of The Davines Group, certified B Corp since 2016.   Website: https://us.comfortzoneskin.com/   Instagram: https://www.instagram.com/comfortzoneskin_official/   Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare   

Real Talk: Eosinophilic Diseases
Predictors of not using medication for EoE

Real Talk: Eosinophilic Diseases

Play Episode Listen Later Nov 19, 2025 44:35


Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Evan S. Dellon, MD, and Elizabeth T. Jensen, PhD, about a paper they published on predictors of patients receiving no medication for treatment of eosinophilic esophagitis. Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:52] Co-host Ryan Piansky introduces the episode, brought to you thanks to the support of Education Partners GSK, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz.   [1:14] Holly introduces today's topic, predictors of not using medication for EoE, and today's guests, Dr. Evan Dellon and Dr. Elizabeth Jensen.   [1:29] Dr. Dellon is an Adjunct Professor of Epidemiology at the University of North Carolina School of Medicine in Chapel Hill. He is also the Director of the UNC Center for Esophageal Diseases and Swallowing.   [1:42] Dr. Dellon's main research interest is in the epidemiology, pathogenesis, diagnosis, treatment, and outcomes of eosinophilic esophagitis (EoE) and eosinophilic GI diseases (EGIDs).   [1:55] Dr. Jensen is a Professor of Epidemiology with a specific expertise in reproductive, perinatal, and pediatric epidemiology. She has appointments at both Wake Forest University School of Medicine and the University of North Carolina at Chapel Hill.   [2:07] Her research primarily focuses on etiologic factors in the development of pediatric immune-mediated chronic diseases, including understanding factors contributing to disparities in health outcomes.   [2:19] Both Dr. Dellon and Dr. Jensen also serve on the Steering Committee for EGID Partners Registry.   [2:24] Ryan thanks Dr. Dellon and Dr. Jensen for joining the podcast today.   [2:29] Dr. Dellon was the first guest on this podcast. It is wonderful to have him back for the 50th episode! Dr. Dellon is one of Ryan's GI specialists. Ryan recently went to North Carolina to get a scope with him.   [3:03] Dr. Dellon is an adult gastroenterologist at the University of North Carolina at Chapel Hill. He directs the Center for Esophageal Diseases and Swallowing. Clinically and research-wise, he is focused on EoE and other eosinophilic GI diseases.   [3:19] His research interests span the entire field, from epidemiology, diagnosis, biomarkers, risk factors, outcomes, and a lot of work, more recently, on treatments.   [3:33] Dr. Jensen has been on the podcast before, on Episode 27. Holly invites Dr. Jensen to tell the listeners more about herself and her work with eosinophilic diseases.   [3:46] Dr. Jensen has been working on eosinophilic gastrointestinal diseases for about 15 years. She started some of the early work around understanding possible risk factors for the development of disease.   [4:04] She has gone on to support lots of other research projects, including some with Dr. Dellon, where they're looking at gene-environment interactions in relation to developing EoE.   [4:15] She is also looking at reproductive factors as they relate to EoE, disparities in diagnosis, and more. It's been an exciting research trajectory, starting with what we knew very little about and building to an increasing understanding of why EoE develops.   [5:00] Dr. Dellon explains that EoE stands for eosinophilic esophagitis, a chronic allergic condition of the esophagus.   [5:08] You can think of EoE as asthma of the esophagus or eczema of the esophagus, although in general, people don't grow out of EoE, like they might grow out of eczema or asthma. When people have EoE, it is a long-term condition.   [5:24] Eosinophils are a type of white blood cell, specializing in allergy responses. Normally, they are not in the esophagus. When we see them there, we worry about an allergic process. When that happens, that's EoE.   [5:40] Over time, the inflammation seen in EoE and other allergic cell activity causes swelling and irritation in the esophagus. Early on, this often leads to a range of upper GI symptoms — including poor growth or failure to thrive in young children, abdominal pain, nausea, and symptoms that can mimic reflux.   [5:58] In older kids, symptoms are more about trouble swallowing. That's because the swelling that happens initially, over time, may turn into scar tissue. So the esophagus can narrow and cause swallowing symptoms like food impaction.   [6:16] Ryan speaks of living with EoE for decades and trying the full range of treatment options: food elimination, PPIs, steroids, and, more recently, biologics.   [6:36] Dr. Dellon says Ryan's history is a good overview of how EoE is treated. There are two general approaches to treating the underlying condition: using medicines and/or eliminating foods that we think may trigger EoE from the diet.   [6:57] For a lot of people, EoE is a food-triggered allergic condition.   [7:01] The other thing that has to happen in parallel is surveying for scar tissue in the esophagus. If that's present and people have trouble swallowing, sometimes stretching the esophagus is needed through esophageal dilation.   [7:14] There are three categories of medicines used for treatment. Proton pump inhibitors are reflux meds, but they also have an anti-allergy effect in the esophagus.   [7:29] Topical steroids are used to coat the esophagus and produce an anti-inflammatory effect. The FDA has approved a budesonide oral suspension for that.   [7:39] Biologics, which are generally systemic medications, often injectable, can target different allergic factors. Dupilumab is approved now, and there are other biologics that are being researched as potential treatments.   [7:51] Even though EoE is considered an allergic condition, we don't have a test to tell people what they are allergic to. If it's a food allergy, we do an empiric elimination diet because allergy tests aren't accurate enough to tell us what the EoE triggers are.   [8:10] People will eliminate foods that we know are the most common triggers, like milk protein, dairy, wheat, egg, soy, and other top allergens. You can create a diet like that and then have a response to the diet elimination.   [8:31] Dr. Jensen and Dr. Dellon recently published an abstract in the American Journal of Gastroenterology about people with EoE who are not taking any medicine for it. Dr. Jensen calls it a real-world data study, leveraging electronic health record patient data.   [8:51] It gives you an impression of what is actually happening, in terms of treatments for patients, as opposed to a randomized control trial, which is a fairly selected patient population. This is everybody who has been diagnosed, and then what happens with them.   [9:10] Because of that, it gives you a wide spectrum of patients. Some patients are going to be relatively asymptomatic. It may be that we arrived at their diagnosis while working them up for other potential diagnoses.   [9:28] Other patients are going to have rather significant impacts from the disease. We wanted to get an idea of what is actually happening out there with the full breadth of the patient population that is getting diagnosed with EoE.   [9:45] Dr. Jensen was not surprised to learn that there are patients who had no pharmacologic treatment.   [9:58] Some patients are relatively asymptomatic, and others are not interested in pursuing medications initially or are early in their disease process and still exploring dietary treatment options.   [10:28] Holly sees patients from infancy to geriatrics, and if they're not having symptoms, they wonder why bother treating it.   [10:42] Dr. Jensen says it's a point of debate on the implications of somebody who has the disease and goes untreated. What does that look like long-term? Are they going to develop more of that fibrostenotic pattern in their esophagus without treatment?   [11:07] This is a question we're still trying to answer. There is some suggestion that for some patients who don't manage their disease, we very well may be looking at a food impaction in the future.   [11:19] Dr. Dellon says we know overall for the population of EoE patients, but it's hard to know for a specific patient. We have a bunch of studies now that look at how long people have symptoms before they're diagnosed. There's a wide range.   [11:39] Some people get symptoms and get diagnosed right away. Others might have symptoms for 20 or 30 years that they ignore, or don't have access to healthcare, or the diagnosis is missed.   [11:51] What we see consistently is that people who may be diagnosed within a year or two may only have a 10 or 20% chance of having that stricture and scar tissue in the esophagus, whereas people who go 20 years, it might be 80% or more.   [12:06] It's not everybody who has EoE who might end up with that scar tissue, but certainly, it's suggested that it's a large majority.   [12:16] That's before diagnosis. We have data that shows that after diagnosis, if people go a long time without treatment or without being seen in care, they also have an increasing rate of developing strictures.    [12:29] In general, the idea is yes, you should treat EoE, because on average, people are going to develop scar tissue and more symptoms. For the patient in front of you with EoE but no symptoms, what are the chances it's going to get worse? You don't know.   [13:04] There are two caveats with that. The first is what we mean by symptoms. Kids may have vomiting and growth problems. Adults can eat carefully, avoiding foods that hang up in the esophagus, like breads and overcooked meats, sticky rice, and other foods.   [13:24] Adults can eat slowly, drink a lot of liquid, and not perceive they have symptoms. When someone tells Dr. Dellon they don't have symptoms, he will quiz them about that. He'll even ask about swallowing pills.    [13:40] Often, you can pick up symptoms that maybe the person didn't even realize they were having. In that case, that can give you some impetus to treat.   [13:48] If there really are no symptoms, Dr. Dellon thinks we're at a point where we don't really know what to do.   [13:54] Dr. Dellon just saw a patient who had a lot of eosinophils in their small bowel with absolutely no GI symptoms. He said, "I can't diagnose you with eosinophilic enteritis, but you may develop symptoms." People like that, he will monitor in the clinic.   [14:14] Dr. Dellon will discuss it with them each time they come back for a clinic visit.   [14:19] Holly is a speech pathologist, but also sees people for feeding and swallowing. The local gastroenterologist refers patients who choose not to treat their EoE to her. Holly teaches them things they should be looking out for.   [14:39] If your pills get stuck or if you're downing 18 ounces during a mealtime, maybe it's time to treat it. People don't see these coping mechanisms they use that are impacting their quality of life. They've normalized it.   [15:30] Dr. Dellon says, of these people who aren't treated, there's probably a subset who appropriately are being observed and don't have a medicine treatment or are on a diet elimination.   [15:43] There's also probably a subset who are inappropriately not on treatment. It especially can happen with students who were under good control with their pediatric provider, but moved away to college and didn't transfer to adult care.   [16:08] They ultimately come back with a lot of symptoms that have progressed over six to eight years.   [16:18] Ryan meets newly diagnosed adult patients at APFED's conferences, who say they have no symptoms, but chicken gets caught in their throat. They got diagnosed when they went to the ER with a food impaction.   [16:38] Ryan says you have to wonder at what point that starts to get reflected in patient charts. Are those cases documented where someone is untreated and now has EoE?   [16:49] Ryan asks in the study, "What is the target EGID Cohort and why was it selected to study EoE? What sort of patients were captured as part of that data set?"   [16:58] Dr. Jensen said they identified patients with the ICD-10 code for a diagnosis of EoE. Then they looked to see if there was evidence of symptoms or complications in relation to EoE. This was hard; some of these are relatively non-specific symptoms.   [17:23] These patients may have been seeking care and may have been experiencing some symptoms that may or may not have made it into the chart. That's one of the challenges with real-world data analyses.   [17:38] Dr. Jensen says they are using data that was collected for documenting clinical care and for billing for clinical care, not for research, so it comes with some caveats when doing research with this data.   [18:08] Research using electronic health records gives a real-world perspective on patients who are seeking care or have a diagnosis of EoE, as opposed to a study trying to enroll a patient population that potentially isn't representative of the breadth of individuals living with EoE.   [18:39] Dr. Dellon says another advantage of real-world data is the number of patients. The largest randomized controlled trials in EoE might have 400 patients, and they are incredibly expensive to do.   [18:52] A study of electronic health records (EHR) is reporting on the analysis of just under 1,000. The cohort, combined from three different centers, has more than 1,400 people, a more representative, larger population.    [19:16] Dr. Dellon says when you read the results, understand the limitations and strengths of a study of health records, to help contextualize the information.   [19:41] Dr. Dellon says it's always easier to recognize the typical presentations. Materials about EoE and studies he has done that led to medicine approvals have focused on trouble swallowing. That can be relatively easily measured.   [20:01] Patients often come to receive care with a food impaction, which can be impactful on life, and somewhat public, if in a restaurant or at work. Typical symptoms are also the ones that get you diagnosed and may be easier to treat.   [20:26] Dr. Dellon wonders if maybe people don't treat some of the atypical symptoms because it's not appreciated that they can be related to EoE.   [20:42] Holly was diagnosed as an adult. Ryan was diagnosed as a toddler. Holly asks what are some of the challenges people face in getting an EoE diagnosis.   [20:56] Dr. Jensen says symptoms can sometimes be fairly non-specific. There's some ongoing work by the CEGIR Consortium trying to understand what happens when patients come into the emergency department with a food bolus impaction.   [21:28] Dr. Jensen explains that we see there's quite a bit of variation in how that gets managed, and if they get a biopsy. You have to have a biopsy of the esophagus to get a diagnosis of EoE.   [21:45] If you think about the steps that need to happen to get a diagnosis of EoE, that can present barriers for some groups to ultimately get that diagnosis.   [21:56] There's also been some literature around a potential assumption about which patients are more likely to be at risk. Some of that is still ongoing. We know that EoE occurs more commonly in males in roughly a two-to-one ratio. Not exclusively in males, obviously, but a little more often in males.   [22:20] We don't know anything about other groups of patients that may be at higher risk. That's ongoing work that we're still trying to understand. That in itself can also be a barrier when there are assumptions about who is or isn't likely to have EoE.   [23:02] Dr. Dellon says that in adolescents and adults, the typical symptoms are trouble swallowing and food sticking, which have many causes besides EoE, some of which are more common.   [23:18] In that population, heartburn is common. Patients may report terrible reflux that, on questioning, sounds more like trouble swallowing than GERD. Sometimes, with EoE, you may have reflux that doesn't improve. Is it EoE, reflux, or both?   [24:05] Some people will have chest discomfort. There are some reports of worsening symptoms with exercise, which brings up cardiac questions that have to be ruled out first.   [24:19] Dr. Dellon mentions some more atypical symptoms. An adult having pain in the upper abdomen could have EoE. In children, the symptoms could be anything in the GI tract. Some women might have atypical symptoms with less trouble swallowing.   [24:58] Some racial minorities may have those kinds of symptoms, as well. If you're not thinking of the condition, it's hard to make the diagnosis.   [25:08] Dr. Jensen notes that there are different cultural norms around expressing symptoms and dietary patterns, which may make it difficult to parse out a diagnosis.   [25:27] Ryan cites a past episode where access to a GI specialist played a role in diagnosing patients with EoE. Do white males have more EoE, or are their concerns just listened to more seriously?   [25:57] Ryan's parents were told when he was two that he was throwing up for attention. He believes that these days, he'd have a much easier time convincing a doctor to listen to him. From speaking to physicians, Ryan believes access is a wide issue in the field.   [26:23] Dr. Dellon tells of working with researchers at Mayo in Arizona and the Children's Hospital of Phoenix. They have a large population of Hispanic children with EoE, much larger than has been reported elsewhere. They're working on characterizing that.   [26:49] Dr. Dellon describes an experience with a visiting trainee from Mexico City, where there was not a lot of EoE reported. The trainee went back and looked at the biopsies there, and it turned out they were not performing biopsies on patients with dysphagia in Mexico City.   [27:13] When he looked at the patients who ended up getting biopsies, they found EoE in 10% of patients. That's similar to what's reported out of centers in the developed world. As people are thinking about it more, we will see more detection of it.   [27:30] Dr. Dellon believes those kinds of papers will be out in the next couple of months, to a year.   [27:36] Holly has had licensure in Arizona for about 11 years. She has had nine referrals recently of children with EoE from Arizona. Normally, it's been one or two that she met at a conference.   [28:00] Ryan asks about the research on patients not having their EoE treated pharmacologically. Some treat it with food avoidance and dietary therapy. Ryan notes that he can't have applesauce, as it is a trigger for his EoE.   [28:54] Dr. Jensen says that's one of the challenges in using the EHR data. That kind of information is only available to the researchers through free text. That's a limitation of the study, assessing the use of dietary elimination approaches.   [29:11] Holly says some of her patients have things listed as allergies that are food sensitivities. Ryan says it's helpful for the patients to have their food sensitivities listed along with their food allergies, but it makes records more difficult to parse for research.   [30:14] Dr. Dellon says they identify EoE by billing code, but the codes are not always used accurately. Natural Language Processing can train a computer system to find important phrases. Their collaborators working on the real-world data are using it.   [30:59] Dr. Dellon hopes that this will be a future direction for this research to find anything in the text related to diet elimination.   [31:32] Dr. Jensen says that older patients were less likely to seek medication therapy. She says it's probably for a couple of reasons. First, older patients may have been living with the disease for a long time and have had compensatory mechanisms in place.   [32:03] The other reason may be senescence or burnout of the disease, long-term. Patients may be less symptomatic as they get older. That's a question that remains to be answered for EoE. It has been seen in some other disease processes.   [32:32] Dr. Dellon says there's not much data specifically looking at EoE in the older population. Dr. Dellon did work years ago with another doctor, and they found that older patients had a better response to some treatments, particularly topical steroids.   [32:54] It wasn't clear whether it was a milder aspect of the disease, easier to treat, or because they were older and more responsible, taking their medicines as prescribed, and having a better response rate. It's the flip side of work in the pediatric population.   [33:16] There is an increasingly aging population with EoE. Young EoE patients will someday be over 65. Dr. Dellon hopes there will be a cure by that point, but it's an expanding population now.   [33:38] Dr. Jensen says only a few sites are contributing data, so they hope to add additional sites to the study. For some of the less common outcomes, they need a pretty large patient sample to ask some of those kinds of questions.   [33:55] They will continue to follow up on some of the work that this abstract touched on and try to understand some of these issues more deeply.   [34:06] Dr. Dellon mentions other work within the cohort. Using Natural Language Processing, they are looking at characterizing endoscopy information and reporting it without a manual review of reports and codes. You can't get that from billing data.   [34:29] Similarly, they are trying to classify patient severity by the Index of Severity with EoE, and layer that on looking at treatments and outcomes based on disease severity. Those are a couple of other directions where this cohort is going.   [34:43] Holly mentions that this is one of many research projects Dr. Jensen and Dr. Dellon have collaborated on together. They also collaborate through EGID Partners. Holly asks them to share a little bit about that.   [34:53] Dr. Jensen says EGID Partners is an online registry where individuals, caregivers, and parents of children affected with EGIDs can join.   [35:07] EGID Partners also needs people who don't live with an EGID to join, as controls. That gives the ability to compare those who are experiencing an EGID relative to those who aren't.   [35:22] When you join EGID Partners, they provide you with a set of questionnaires to complete. Periodically, they push out a few more questionnaires.   [35:33] EGID Partners has provided some really great information about patient experience and answered questions that patients want to know about, like joint pain and symptoms outside the GI tract.   [36:04] To date, there are close to 900 participants in the registry from all over the world. As it continues to grow, it will give the ability to look at the patient experience in different geographical areas.   [36:26] Dr. Dellon says we try to have it be interactive, because it is a collaboration with patients. The Steering Committee works with APFED and other patient advocacy groups from around the world.    [36:41] The EGID Partners website shows general patient locations anonymously. It shows the breakdown of adults with the condition and caregivers of children with the condition, the symptom distribution, and the treatment distribution.   [37:03] As papers get published and abstracts are presented, EGID Partners puts them on the website. Once someone joins, they can suggest a research idea. Many of the studies they have done have come from patient suggestions.   [37:20] If there's an interesting idea for a survey, EGID Partners can push out a survey to everybody in the group and answer questions relatively quickly.   [37:57] Dr. Dellon says a paper came out recently about telehealth. EoE care, in particular, is a good model for telehealth because it can expand access for patients who don't have providers in their area.   [38:22] EoE is a condition where care involves a lot of discussion but not a lot of need for physical exams and direct contact, so telehealth can make things very efficient.    [38:52] EGID Partners surveyed patients about telehealth. They thought it was efficient and saved time, and they had the same kind of interactions as in person. In general, in-state insurance covered it. Patients were happy to do those kinds of visits again.   [39:27] Holly says Dr. Furuta, herself, and others were published in the Gastroenterology journal in 2019 about starting to do telehealth because patients coming to the Children's Hospital of Colorado from out of state had no local access to feeding therapy.   [39:50] Holly went to the board, and they allowed her to get licensure in different states. She started with some of the most impacted patients in Texas and Florida in 2011 and 2012. They collected data. They published in 2019 about telehealth's positive impact.   [40:13] When 2020 rolled around, Holly had trained a bunch of people on how to do feeding therapy via telehealth. You have to do all kinds of things, like make yourself disappear, to keep the kids engaged and in their chairs!   [40:25] Now it is Holly's primary practice. She has licenses in nine states. She sees people all over the country. With her diagnosis, her physicians at Mass General have telehealth licensure in Maine. She gets to do telehealth with them instead of driving two hours.   [40:53] Dr. Jensen tells of two of the things they hope to do at EGID Partners. One is trying to understand more about reproductive health for patients with an EGID diagnosis. Only a few studies have looked at this question, and with very small samples.   [41:15] As more people register for EGID Partners, Dr. Jensen is hoping to be able to ask some questions related to reproductive health outcomes.   [41:27] The second goal is a survey suggested by the Student Advisory Committee, asking questions related to the burden of disease specific to the teen population.   [41:48] This diagnosis can hit that population particularly hard, at a time when they are trying to build and sustain friendships and are transitioning to adult care and moving away from home. This patient population has a unique perspective we wanted to hear.   [42:11] Dr. Jensen and Dr. Dellon work on all kinds of other projects, too.   [42:22] Dr. Dellon says they have done a lot of work on the early-life factors that may predispose to EoE. They are working on a large epidemiologic study to get some insight into early-life factors, including factors that can be measured in baby teeth.   [42:42] That's outside of EGID Partners. It's been ongoing, and they're getting close, maybe over the next couple of years, to having some results.   [43:03] Ryan says all of those projects sound so interesting. We need to have you guys back to dive into those results when you have something finalized.   [43:15] For our listeners who want to learn more about eosinophilic disorders, we encourage you to visit apfed.org and check out the links in the show notes below.   [43:22] If you're looking to find specialists who treat eosinophilic disorders, we encourage you to use APFED's Specialist Finder at apfed.org/specialist.   [43:31] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at apfed.org/connections.   [43:41] Ryan thanks Dr. Dellon and Dr. Jensen for joining us today. This was a fantastic conversation. Holly also thanks APFED's Education Partners GSK, Sanofi, Regeneron, and Takeda for supporting this episode.   Mentioned in This Episode: Evan S. Dellon, MD, MPH, Academic Gastroenterologist, University of North Carolina School of Medicine   Elizabeth T. Jensen, MPH, PhD, Epidemiologist, Wake Forest University School of Medicine, University of North Carolina at Chapel Hill   Predictors of Patients Receiving No Medication for Treatment of Eosinophilic Esophagitis in the United States: Data from the TARGET-EGIDS Cohort   Episode 15: Access to Specialty Care for Eosinophilic Esophagitis (EoE)   APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections apfed.org/research/clinical-trials   Education Partners: This episode of APFED's podcast is brought to you thanks to the support of GSK, Sanofi, Regeneron, and Takeda.   Tweetables:   "I've been working on eosinophilic gastrointestinal diseases for about 15 years. I started some of the early work around understanding possible risk factors for the development of disease. I've gone on to support lots of other research projects." — Elizabeth T. Jensen, MPH, PhD   "You can think of EoE as asthma of the esophagus or eczema of the esophagus, although in general, people don't grow out of EoE, like they might grow out of eczema or asthma. When people have it, it really is a long-term condition." — Evan S. Dellon, MD, MPH   "There are two general approaches to treating the underlying condition, … using medicines and/or eliminating foods from the diet that we think may trigger EoE. I should say, for a lot of people, EoE is a food-triggered allergic condition." — Evan S. Dellon, MD, MPH   "I didn't find it that surprising [that there are patients who had no treatment]. Some patients are relatively asymptomatic, and others are not interested in pursuing medications initially or are … still exploring dietary treatment options." — Elizabeth T. Jensen, MPH, PhD   "We have a bunch of studies now that look at how long people have symptoms before they're diagnosed. There's a wide range. Some people get symptoms and are diagnosed right away. Other people might have symptoms for 20 or 30 years." — Evan S. Dellon, MD, MPH   "EGID Partners is an online registry where individuals, caregivers, and parents of children affected with EGIDs can join. EGID Partners also needs people who don't live with an EGID to join, as controls." — Elizabeth T. Jensen, MPH, PhD

Darkest Mysteries Online - The Strange and Unusual Podcast 2023
People who have been clinically dead and came back, how was the other side like

Darkest Mysteries Online - The Strange and Unusual Podcast 2023

Play Episode Listen Later Nov 19, 2025 59:56


People who have been clinically dead and came back, how was the other side likeBecome a supporter of this podcast: https://www.spreaker.com/podcast/darkest-mysteries-online-the-strange-and-unusual-podcast-2025--5684156/support.Darkest Mysteries Online

Inspire Change with Gunter
Inspire Change SEASON 7-309 The Man Box for Boys

Inspire Change with Gunter

Play Episode Listen Later Nov 19, 2025 29:10 Transcription Available


This week on Inspire Change...Gunter  #InspireChange #Philosophy #Science #Reflection #Contemplation #SelfDevelopment #Masculinity #MakingGoodMenGreat #stoicism We have now partnered with sponsors that promote well-being, wellness and mental health.So it's that time of the year again! Yes, you heard me, THE HOLIDAYS are fast approaching and we all know what that means…parties, gatherings, work and business socials.  Science has evolved and there is no reason to waste time trying to recover from a night of celebrating. You may know what I mean if you have EVER had a few too many, that dreaded next morning where your head is pounding and you can't fathom the thought of getting up to use the rest room. Horrible! That's why we  believe in the scientific triumph that is Morning Recovery. It's scientifically formulated to help you bounce back after a night of drinking. It's made with ingredients like Milk Thistle and ginseng to help you recover from last night's festivities. Plus it's loaded with electrolytes and B Vitamins that replenish lost nutrients. It is seriously a game changer, your new “drink one before having a good time”, and wake up ready for anything drink!More Labs' Morning Recovery is the #1 alcohol recovery supplement that helps you wake up clear-headed and refreshed. Clinically proven and trusted by thousands, with 20M+ bottles sold and a 4.9-star rating, it works. Try it risk-free! Enjoy an exclusive discount with our promo code https://www.morelabs.com/discount/INSPIRECHANGE Our code will be applied to your cart and you get a discount at any of the products at MoreLabs.com Their products are loaded with super ingredients—Milk Thistle, Prickly Pear, Red Ginseng, Electrolytes, and B Vitamins. It is Developed with top scientists—including Dr. Fu Chen, a former FDA expert in supplement absorption. MoreLabs products work better than sports drinks—targets toxin buildup and nutrient loss, not just dehydration. Their products are a clean formula—no artificial colors, sweeteners, or preservatives.  It is also portable & TSA-friendly—perfect for travel, work, or big nights out.This week we would like to express our gratitude to those of you listening in Alaska. Your continued support has brought Alaska to #8 on the Top 10 Listeners List, for the first time EVER! CONGRATULATIONS!!!  and Thank you to  all our listeners in Anchorage for bringing your state to #8 and our deepest gratitude for promoting positive social change. We now take a list at the Global Listeners, and want to give a big CONGRATULATIONS to Trinidad and Tobago for entering the top 25 Global Listeners List!  We cannot express how grateful we are for your continued support around the world!  Thank you to all of our listeners for tuning in & supporting Positive Global Social Change.   This makes you a part of Gunter's efforts in transforming not only men's lives but lives in general and we are grateful you have joined us.  I, DeVonna Prinzi the Co-Exec Producer and our Showrunner Miranda Spigener-Sapon sincerely thank you and ask that you please take the time to like, follow, subscribe, and share as your efforts make a difference to everyone here at Inspire Change with Gunter.   Please remember If you want to share your story of social change, feel free to reach out  to the show directly. Please see the show-notes for our contact information.  As always thank you to each and every one of our listeners, and most importantly please keep Inspiring positive social change.Become a supporter of this podcast: https://www.spreaker.com/podcast/inspire-change-with-gunter--3633478/support.Gunter Swoboda and Lorin Josephson's neo-noir/supernatural thriller novel Amulets of Power, Book I A Brian Poole Mystery is officially ON SALE EVERYWHERE you like to get book, but if you want a discount please consider ording direct. ANY LISTENER who order's direct will get a surprise gift. https://shop.ingramspark.com/b/084?params=3RoOA6kVQ7ZgmqSK9LdnvNyDAZZFsg9IMaLUaprPgXKMake sure you LIKE SUBSCRIBE & FOLLOW our new Official YouTube Channel of Video Shorts series: https://www.youtube.com/@InspireChangewithGunterSwoboda/videos where we will be adding new videos and content every week from Gunter and our guests.  https://www.youtube.com/@InspireChangewithGunterSwoboda/videos

AJR Podcast Series
How Good is PI-RADS v2.1 in the Detection of Clinically Significant Prostate Cancer on Prostate MRI?

AJR Podcast Series

Play Episode Listen Later Nov 17, 2025 7:52


Full article: PI-RADS Version 2.1 for Prostate MRI Interpretation: Associations of Study Quality and Cancer Detection Metrics—A Systematic Review and Meta-Analysis Research quality can influence the results of studies evaluating PI-RADS performance. Tobi Folami, MD, discusses this AJR article by Nedelcu et al. reporting a meta-analysis of PI-RADS v2.1 performance, with attention to the impact of study quality.

The Jillian Michaels Show
Jillian Michaels: No More Hostage to the Clinically Insane—Exposing Cowardice in Both Parties

The Jillian Michaels Show

Play Episode Listen Later Nov 14, 2025 10:22


Jillian Michaels addresses the pressing issue of cowardice in American politics, arguing that the real problem isn't extremism but the lack of courage to confront it. She discusses how both Democrats and Republicans avoid holding their own extremists accountable, resulting in a more mainstream presence of fringe ideologies. Jillian also calls for responsible leadership, emphasizing the need to marginalize actual hatred and promote a shared standard of decency and accountability.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Jillian Michaels Show
Jillian Michaels: No More Hostage to the Clinically Insane — Extremism & Cowardice in Both Parties 

The Jillian Michaels Show

Play Episode Listen Later Nov 14, 2025 8:11


Jillian Michaels addresses the pressing issue of cowardice in American politics, arguing that the real problem isn't extremism but the lack of courage to confront it. She discusses how both Democrats and Republicans avoid holding their own extremists accountable, resulting in a more mainstream presence of fringe ideologies. Jillian also calls for responsible leadership, emphasizing the need to marginalize actual hatred and promote a shared standard of decency and accountability. 

The Incubator
#375 -

The Incubator

Play Episode Listen Later Nov 12, 2025 20:23


Send us a textThis keynote episode features Dr. Jennifer Sucre (Vanderbilt University Medical Center), whose research bridges bedside observation and molecular biology to uncover why some preterm infants develop severe bronchopulmonary dysplasia (BPD) while others recover. Through innovative live imaging of lung development and mouse and human tissue models, her lab discovered that capillary “guidance” signals—semaphorins—are crucial for lung repair and resilience. Loss of these pathways marks irreversible injury. Dr. Sucre emphasizes “bedside-to-bench” science, finding lessons from resilient infants to inform therapy. Clinically, she urges providers to recognize individual resilience, foster hopeful communication with families, and envision a future where BPD is preventable—not inevitable.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

ASCP Esty Talk
Ep 360– Social Media P's and Q's

ASCP Esty Talk

Play Episode Listen Later Nov 12, 2025 14:12


Think before you post! Maggie and Ella dive into the fine line between authentic and unfiltered on social media. From oversharing and online debates to digital etiquette, they explore how estheticians can protect their reputation and their community—one post at a time.   ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   Comfort Zone – The Italian, multi-awarded science-led, longevity-focused skincare trusted by professionals worldwide. Founded by Dr Bollati, a pharmacist, and powered by over 60 in-house chemists and skin care experts. Clinically tested formulations blend clinical precision, regenerative botanicals, and biotechnology research to transform skin with intention. Part of The Davines Group, certified B Corp since 2016.   Website: https://us.comfortzoneskin.com/   Instagram: https://www.instagram.com/comfortzoneskin_official/   Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare   

Atomic Anesthesia
ETOMIDATE + ADRENAL SUPPRESSION: IS IT CLINICALLY RELEVANT?│ EP64

Atomic Anesthesia

Play Episode Listen Later Nov 12, 2025 15:55


This episode of the Atomic Anesthesia Podcast unpacks the real clinical risk of adrenal suppression after a single dose of etomidate, challenging common debates every anesthesia resident faces. Drawing on the latest studies, listeners will discover exactly which patient groups—cardiac, septic, trauma, pediatric, and elective—are actually vulnerable to etomidate's effects, and when transient adrenal suppression matters for outcomes. The discussion highlights the drug's unique origins, why its hemodynamic stability often outweighs risks in routine cases, and why infusions are off the table. Tune in for practical guidance on using etomidate safely, tips for steroid coverage in critically ill patients, and a sneak peek at promising new etomidate analogs. Whether you're prepping for exams or your next high-stakes induction, this episode helps you make smarter, evidence-based choices in the OR..Want to learn more? Create a FREE account at www.atomicanesthesia.com⚛️ CONNECT:

For the Sake of the Child
Special Education Advocacy for Military Families

For the Sake of the Child

Play Episode Listen Later Nov 11, 2025 28:38


Partners in PROMISE is a nonprofit organization whose mission is to Protect the Rights of Military children in Special Education and disability communities to ensure they receive equal access to an education.  Listen as Dr. Jenna Kremkow and Carla Wyrsch discuss how the PROMISE advocates for military children with special and exceptional needs.   This podcast is made possible by generous funding from the Luke Spouses' Club. To learn more, visit https://www.lukespousesclub.org/.   Audio mixing by Concentus Media, Inc., Temple, Texas.   Show Notes:   Resources:   Partners in PROMISE https://thepromiseact.org/   Partners in PROMISE Special Education & EFMP Binder  https://thepromiseact.org/binder/   Educator Report https://thepromiseact.org/educators-report-partners-in-promise-2022-research-findings/   Bio: Jenna Kremkow is an associate professor in the Department of Communication Sciences and Disorders at Elmhurst University. She completed her MS and PhD at The Pennsylvania State University with an emphasis in autism, augmentative and alternative communication, child language disorders, and stakeholder training and perspectives. Clinically, Jenna has worked as a speech-language pathologist in elementary schools, outpatient clinics, and early intervention settings. Jenna teaches courses in augmentative and alternative communication, autism, language disorders in children, and research methods. One of her research areas focuses on the experiences of military families with children with autism and the use of technology to improve communication outcomes and quality of life for children with autism and their families. Her goal is to use research to support data-driven recommendations and policy changes to improve special education services for military families.     Carla Wyrsch is the spouse of a retired United States Marine and mother of two. She has devoted her career to educating and advocating for children with disABILITIES. Her experience spans a variety of settings, including residential treatment facilities, military bases, public schools, and the Lerner School for Autism at the Cleveland Clinic. Currently, she is a School Operations Director with MIYO Health. In addition to her work with MIYO Health, Carla enjoys volunteering with Best Buddies of Greater Memphis, the Organization for Autism Research, and Partners in PROMISE as a content creator and advisory board member.

The Back Doctors Podcast with Dr. Michael Johnson
306 - Christi Thompson - StretchLab

The Back Doctors Podcast with Dr. Michael Johnson

Play Episode Listen Later Nov 10, 2025 26:23


Christi Thompson from StretchLab shares a story of a nurse who gets back pain relief from one-on-one assisted stretching. Christi Thompson Master Instructor | Area Education Manager | Member, Master Trainer Advisory Council 2025 Christi Thompson is a dedicated Master Instructor at StretchLab and a member of the 2025 Master Trainer Advisory Council. Since joining the StretchLab team in 2019 as a Flexologist in Dilworth (Charlotte, NC), Christi has demonstrated a clear trajectory of growth—progressing to Lead Flexologist in Fort Mill, SC, and achieving the title of Master Instructor in 2022. She currently serves as the Area Education Manager for her local franchise, where she oversees the onboarding and continued education of Flexologists, equipping them with the skills and support necessary to thrive in their roles. Christi holds a Bachelor's degree in Athletic Training from the University of Delaware and a Master's degree in Athletic Training from the University of North Carolina at Chapel Hill. Her academic research focused on functional fatigue and its impact on body mechanics and injury risk. Clinically, she has worked with top-tier Division I athletics programs at UNC-Chapel Hill, including baseball and field hockey. After graduate school, she continued her career at Raleigh Orthopedic's Athletic Performance Center, where she worked with professional and youth athletes, including those affiliated with the Carolina Hurricanes NHL team. Before joining StretchLab, Christi also spent time as a high school teacher in biology and earth and environmental science. She earned her teaching certificate from North Carolina State University, where she studied teaching theory and psychology—skills she applies daily in her current leadership and education roles. Outside of her professional life, Christi is passionate about horseback riding and ultramarathon running. Having grown up in an equestrian household, she has been riding since childhood and currently leases and cares for a quarter horse named Luna. Christi is also a committed endurance athlete, with several ultramarathon finishes—including 50K and 50-mile distances—and plans to pursue 100K and 100-mile races. She values the mental resilience, strategic training, and love of the outdoors that the sport fosters.   Resources: Christi Thompson | Area Education Manager - StretchLab Charlotte & Columbia C: 302.530.0321  - call or text W: stretchlab.com Show sponsor: Haven Medical  

ASCP Esty Talk
Ep 358 – From Ingredients to Outcomes

ASCP Esty Talk

Play Episode Listen Later Nov 5, 2025 16:27


What happens when skin care stops being about "what's in it" and starts being about "what it does?". In this episode of ASCP Esty Talk, Maggie and Ella dive into the industry's shift from ingredient obsession to outcomes, exploring skin health as part of overall wellness and health span. ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   Comfort Zone – The Italian, multi-awarded science-led, longevity-focused skincare trusted by professionals worldwide. Founded by Dr Bollati, a pharmacist, and powered by over 60 in-house chemists and skin care experts. Clinically tested formulations blend clinical precision, regenerative botanicals, and biotechnology research to transform skin with intention. Part of The Davines Group, certified B Corp since 2016.   Website: https://us.comfortzoneskin.com/   Instagram: https://www.instagram.com/comfortzoneskin_official/   Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare   

Naturally Nourished
Episode 468: Sulforaphane

Naturally Nourished

Play Episode Listen Later Nov 3, 2025 40:13


Have you heard of sulforaphane? Want to know how to harness the benefits of this powerful compound? Tune in to learn all about sulforaphane—a powerhouse phytonutrient that activates detox and antioxidant pathways to protect your cells.  In this episode, we will unpack how this potent compound supports the body's natural defense systems, working through the NRF2 pathway to reduce oxidative stress, enhance cellular detoxification, and promote resilience against modern day toxin exposure. We also discuss how food preparation impacts sulforaphane yield, why gut health matters for its conversion, and how to maximize levels through broccoli sprouts, seed extracts, and targeted supplementation.  We also unveil the exciting reformulation of Cellular Antiox, featuring clinically validated broccoli seed extract for enhanced cellular protection alongside glutathione support! Also in this episode:  Shop NEW Cellular Antiox with code CELLULAR15 Naturally Nourished Academy - Now Enrolling with Early Bird Pricing!  What is sulforaphane? Who can benefit from sulforaphane? Sulforaphane in the research Randomized Phase II Clinical Trial of Sulforaphane in Former Smokers at High Risk for Lung Cancer - PubMed Rapid and Sustainable Detoxication of Airborne Pollutants by Broccoli Sprout Beverage: Results of a Randomized Clinical Trial in China - PMC Sulforaphane-rich broccoli sprout extract improves hepatic abnormalities in male subjects - PubMed Effects of broccoli sprout supplements enriched in glucoraphanin on liver functions in healthy middle-aged adults with high-normal serum hepatic biomarkers: A randomized controlled trial Long-lasting beneficial effects of maternal intake of sulforaphane glucosinolate on gut microbiota in adult offspring - ScienceDirect Broccoli or Sulforaphane: Is It the Source or Dose That Matters? - PMC Sulforaphane treatment of autism spectrum disorder (ASD) | PNAS Prep and cooking to maximize sulforaphane Why the gut microbiome matters Probiotic Challenge Protocol How to get sulforaphane in the diet Considerations for BroccoDetox New Cellular Antiox Formulation Setria® Glutathione (250 mg): Clinically studied, reduced form, ready to use N-Acetylcysteine (1,000 mg): A powerful precursor, provides cysteine to fuel internal glutathione production Broccoli Seed Extract 40mg (2mg glucoraphanin): Activates Nrf2 pathway, upregulates endogenous antioxidant production, including glutathione Vitamin B6 (5 mg): Essential cofactor for amino acid metabolism and methylation, supports efficient detox and glutathione recycling New bovine gelatin capsule with silica as an added feature!   Sponsors for this episode:  This episode is sponsored by FOND Bone Broth, your sous chef in a jar. FOND's bone broths and tallows are produced in small batches with premium ingredients from verified regenerative ranches. Their ingredients are synergistically paired for maximum absorption, nutritional benefit, and flavor. Use code NATURALLY to save at fondbonebroth.com 

The ADHD Skills Lab
Understanding ADHD Medication: A Balanced Look at the Science

The ADHD Skills Lab

Play Episode Listen Later Nov 3, 2025 40:01


ADHD medication can be a controversial topic online. Is it safe? Does it change who you are? What does the science actually say?In this episode, Skye talks with Dr. Ryan Sultan, psychiatrist, researcher, and founder of Integrative Psychiatry in NYC, about what medication does in the brain and what decades of studies reveal about its effects. This is not medical advice - it's a clear, evidence-based conversation to help you understand your options.What we cover:How ADHD medication affects dopamine and focusThe difference between stimulant and non-stimulant medicationsWhy safety and addiction concerns often get misunderstoodHow to approach treatment decisions from an informed placeHow to know if your treatment plan needs adjustmentThe role of therapy, structure, and lifestyle alongside medicationDr. Ryan Sultan, MD is a double board-certified psychiatrist, Assistant Professor of Clinical Psychiatry at Columbia, and the Founder & Medical Director of Integrative Psychiatry in Chelsea, NYC, and Miami, FL. He leads NIH-funded research on ADHD and comorbidities and has published in JAMA, The Journal of Adolescent Health, and JAACAP. Clinically, he works with children and adults navigating conditions like anxiety, depression, and substance use.Medical Disclaimer:This episode is for educational purposes only and does not constitute medical advice.Skye Waterson is not a medical doctor and does not make treatment recommendations.Always consult a qualified healthcare professional before making any decisions about diagnosis, medication, or treatment for ADHD or any other condition.P.S. If you feel like the bottleneck in your business and life feels like chaos, click here to apply for a call with me. We'll discuss your struggles and explore systems to support you in growing without the overwhelm.

Naturally Nourished
Episode 467: How to Raise Your Glutathione Stores + New Cellular Antiox

Naturally Nourished

Play Episode Listen Later Oct 27, 2025 50:27


Are you low in glutathione? Feeling sluggish, inflamed, or more sensitive to toxins than you used to be? Maybe you're catching every bug that goes around or noticing your recovery just isn't what it used to be. Today on the Naturally Nourished Podcast, we're talking about the body's master antioxidant, glutathione, and why it's essential for immune resilience, detoxification, energy, and longevity. We'll unpack what glutathione is, why modern life so easily depletes it, and how low levels have been linked to everything from fatigue and joint pain to accelerated aging and chronic disease. Plus, we'll share simple strategies to help you raise your levels naturally and introduce our newly reformulated Cellular Antiox, now featuring NAC, Setria® glutathione, and broccoli seed extract for enhanced cellular protection and glutathione production. Use the code CELLULAR15 to save 15% off our exciting reformulation of Cellular Antiox! Also in this episode:  What is glutathione and what does it do? Episode 325 All About Glutathione Trends of deficiency Micronutrient Panel How the body produces glutathione Cysteine Whey Protect Glycine Pure Collagen Relax and Regulate Glutamate GI Lining Support Do we store glutathione and does it need to be replenished? How to increase glutathione  Sulfur rich veggies Modulation of plasma antioxidant levels, glutathione S‐transferase activity and DNA damage in smokers following a single portion of broccoli: a pilot study Bone broth FOND Bone Broth use code ALIMILLERRD When to supplement with glutathione Will supplementation make my body stop producing it on its own? NEW Cellular Antiox reformulation A 2015 randomized, double-blind, placebo-controlled study published in the European Journal of Nutrition showed that 250–1000 mg of Setria daily for 6 months significantly increased glutathione levels in whole blood, red blood cells, and lymphocytes. Per 2 Capsules: Setria® Glutathione (250 mg): Clinically studied, reduced form, ready to use N-Acetylcysteine (1,000 mg): A powerful precursor, provides cysteine to fuel internal glutathione production Broccoli Seed Extract 40mg (2mg glucoraphanin): Activates Nrf2 pathway, upregulates endogenous antioxidant production, including glutathione Vitamin B6 (5 mg): Essential cofactor for amino acid metabolism and methylation, supports efficient detox and glutathione recyclingNew bovine gelatin capsule with silica as an added feature! Comparison to liposomal and IV glutathione How to dose 1 capsule twice daily for wellness 2 capsules 2-3 times daily for illness or infection Making Medicinal Honey   This episode is sponsored by: This episode is sponsored by Wild Foods, a company that puts quality, sustainability, and health first in all of their products. They have everything from coffee to turmeric to medicinal mushrooms, and every single product is painstakingly sourced from small farms around the globe. They take their mission seriously to fix the broken food system, and believe real food is medicine. They've partnered with us to give you guys an exclusive discount, so use the code ALIMILLERRD for 12% off your order at WildFoods.co! 

Next Level Soul with Alex Ferrari: A Spirituality & Personal Growth Podcast
FLASHBACK FRIDAYS: Clinically DEAD Woman Meets LIGHT BEINGS During PROFOUND Near Death Experience! (NDE) with Susan Dyer

Next Level Soul with Alex Ferrari: A Spirituality & Personal Growth Podcast

Play Episode Listen Later Oct 24, 2025 59:35 Transcription Available


Catholics. During a near-death experience in 2017, Susan merged with an unnamable “God” and has mentored awakening women since.She graduated from Hamilton College with a Bachelor of Arts in Cultural Anthropology. Her work has appeared in Dance Magazine, FOLIO, Burningword, and Evening Street Review.Become a supporter of this podcast: https://www.spreaker.com/podcast/next-level-soul-podcast-with-alex-ferrari--4858435/support.

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Airsupra is a combination inhaler that contains albuterol and budesonide, approved for as-needed use in adults with asthma. It represents the first rescue inhaler to combine a short-acting beta-2 agonist (SABA) with an inhaled corticosteroid (ICS) in a single device. The albuterol component provides rapid bronchodilation by relaxing airway smooth muscle, while budesonide works to reduce airway inflammation and mucus production. This dual mechanism allows Airsupra to not only relieve acute bronchoconstriction but also address the underlying inflammatory process that contributes to asthma exacerbations. Clinically, Airsupra is indicated for as-needed treatment or prevention of bronchoconstriction in adults with asthma, but it is not approved for COPD. The typical dosing is two inhalations as needed, with a maximum of six doses (12 inhalations) in a 24-hour period. The rationale for its use aligns with recent asthma guideline updates, which emphasize minimizing SABA-only use because it fails to address inflammation and may contribute to worse outcomes over time. Common adverse effects include tremor, nervousness, tachycardia, and hypokalemia from albuterol, as well as oral thrush and hoarseness from budesonide. Patients should rinse and spit after each use to reduce the risk of oral candidiasis. Drug interactions can occur with non-selective beta-blockers, which may blunt albuterol's effects. CYP3A4 also plays a role in budesonide metabolism. Systemic absorption typically isn't too much of an issue with infrequent use.

The Model Health Show
The Truth About Red Light Therapy and Using Light as Medicine

The Model Health Show

Play Episode Listen Later Oct 20, 2025 25:44


Red light therapy has started to gain traction in popular culture. From sports medicine recovery to beauty treatments, more and more people are starting to catch on to the benefits of using red light. But why does red light therapy work? And what are its science-backed benefit? On today's show, we're going to dive into the science of red light therapy. You're going to learn how light therapy can help reduce pain, enhance skin quality, improve the symptoms of certain disorders, and so much more! You're also going to learn about other types of light therapy, like ultraviolet and green light therapy. We're going to discuss the health benefits of getting adequate sunlight, why human biology is so responsive to input from light sources, and how to integrate more light into your routine. Enjoy!   In this episode you'll discover:  How red light therapy can help reduce pain. (0:21) The link between red light exposure and wrinkle reduction. (1:22) Which bacteria has been shown to be reduced by far UV light. (2:09) How red light therapy can help with muscle growth. (2:45) The science behind why the human body is so responsive to light. (5:09) How your circadian timing system works. (5:47) The #1 influencer of your circadian clocks. (6:26) How mitochondria respond to red light therapy. (7:38) A fascinating study on hypothyroidism and red light therapy. (11:19) The link between light therapy and fat loss. (17:28) What the ultimate source of light therapy is. (23:09)  Items mentioned in this episode include:  ⁠Thelumebox.com/model⁠  -  Experience the next-level benefits of red light therapy at home? Enjoy an exclusive $260 off the premium LUMEBOX red light therapy system, designed to boost recovery, skin health, and overall vitality. Be sure you are subscribed to this podcast to automatically receive your episodes:   ⁠Apple Podcasts⁠ ⁠Spotify⁠ ⁠Soundcloud⁠ ⁠Pandora⁠ ⁠YouTube⁠   This episode of The Model Health Show is brought to you by Lumebox. Clinically-designed to deliver both red (660 nm) and near-infrared (850 nm) wavelengths in one sleek handheld device.Independently lab-tested for performance: more coverage, higher irradiance, greater effect. Perfect for skin health, pain support, recovery and overall vitality — in your routine, on your terms. Use this link to claim your discount: ⁠thelumebox.com/model⁠ to claim or $260 off your device.   Learn more about your ad choices. Visit megaphone.fm/adchoices

Podcast – CrimsonCast
Ep 1269 - Indiana Football is 7-0 After Clinically Dispatching of Michigan State

Podcast – CrimsonCast

Play Episode Listen Later Oct 19, 2025 65:40


Galen Clavio and Scott Caulfield recap Indiana's 38–13 win over Michigan State — a dominant, businesslike homecoming victory. They break down Fernando Mendoza's near-perfect day, IU's offensive balance, the defense's steady control, and how the Hoosiers continue proving they belong among the nation's best.Presented by Homefield Apparel.

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

In this episode of Real Life Pharmacology, we take a deep dive into daptomycin, a lipopeptide antibiotic primarily used for serious Gram-positive infections, including MRSA and VRE. Daptomycin works by binding to bacterial cell membranes in a calcium-dependent manner, causing rapid depolarization and cell death. One key limitation is that daptomycin should never be used for pneumonia because pulmonary surfactant inactivates the drug. Clinically, it's often reserved for bacteremia, endocarditis, or complicated skin and soft tissue infections. From a pharmacokinetic standpoint, daptomycin is given intravenously and primarily eliminated unchanged by the kidneys, so dose adjustments are necessary in renal impairment. Monitoring creatine kinase (CK) levels is crucial, as one of the major adverse effects is myopathy and, rarely, rhabdomyolysis. Patients on statins have a higher risk of muscle toxicity, and clinicians should consider holding or monitoring statin therapy closely. Eosinophilic pneumonia is another rare but serious adverse reaction that can develop after prolonged therapy. Daptomycin has minimal drug interactions, making it an appealing option when other agents pose risks. Overall, it's a powerful antibiotic when used appropriately, but requires careful monitoring for muscle and respiratory-related side effects.

The Other Side NDE (Near Death Experiences)
Bob Proctor - Clinically Dead Man Shown Shocking Truth About Death And Reincarnation (NDE)

The Other Side NDE (Near Death Experiences)

Play Episode Listen Later Oct 14, 2025 20:49


For The Other Side NDE Videos Visit ▶️ youtube.com/@TheOtherSideNDEYT Purchase our book on Amazon

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Cefepime is a fourth-generation cephalosporin antibiotic with broad-spectrum activity against both gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. It works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins, leading to cell lysis and death. Clinically, cefepime is commonly used in hospital settings for serious infections such as pneumonia, febrile neutropenia, urinary tract infections, skin infections, and intra-abdominal infections. It's typically administered intravenously, with doses often ranging from 1 to 2 grams every 8 to 12 hours depending on the indication and renal function. From a pharmacokinetic standpoint, cefepime is primarily renally eliminated, so dose adjustments are required in patients with impaired kidney function. Failure to reduce the dose appropriately can lead to neurotoxicity — one of the key adverse effects associated with cefepime — manifesting as encephalopathy, confusion, myoclonus, or seizures, particularly in elderly or renally impaired patients. Common side effects include gastrointestinal upset and rash. Cefepime has relatively limited drug interactions, though concurrent nephrotoxic agents can increase the risk of renal injury.

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Midodrine is an oral alpha-1 agonist most commonly used for the treatment of symptomatic orthostatic hypotension. Its mechanism of action is through peripheral vasoconstriction, which helps increase blood pressure. Because of its short duration of action, it is typically dosed three times daily, with the last dose recommended in the late afternoon to reduce the risk of hypertension at night. Clinically, midodrine is often considered when non-pharmacologic strategies for orthostatic hypotension (such as increased salt/fluid intake, compression stockings, or physical counter-maneuvers) are not enough. Pharmacists should also be aware of prescribing cascades—such as urinary retention leading to tamsulosin initiation—that can arise when midodrine is used. Midodrine is generally not metabolized through cytochrome P450 pathways, so significant drug–drug interactions are less common. However, caution should be exercised with other agents that can raise blood pressure (like decongestants) or slow the heart rate (such as beta-blockers). Monitoring parameters include blood pressure, pulse, symptoms of urinary retention, and the patient's overall response to therapy.

American Conservative University
Clinically Dead, Walking with Jesus for 44 Hours - NDE Miracle!: Robert Marshall.

American Conservative University

Play Episode Listen Later Sep 20, 2025 88:30


Clinically Dead, Walking with Jesus for 44 Hours - NDE Miracle!: Robert Marshall. When Robert Marshall went into cardiac arrest, he was clinically dead—no heartbeat, no breath—for 44 hours. During that time, he says he was fully conscious in heaven, with Jesus. What he witnessed was beyond anything imaginable: harmonic trees, divine light, and a mission he didn't want but ultimately accepted.

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Revefenacin (brand name Yupelri) is a long-acting muscarinic antagonist (LAMA) used for the maintenance treatment of chronic obstructive pulmonary disease (COPD). It works by blocking muscarinic receptors, particularly the M3 subtype, in airway smooth muscle. This antagonism reduces cholinergic bronchoconstriction and leads to sustained bronchodilation. Unlike short-acting anticholinergics such as ipratropium, revefenacin provides 24-hour bronchodilation with once-daily dosing. One of the distinguishing features of revefenacin is that it is the first nebulized LAMA approved for COPD maintenance therapy. Many patients with advanced COPD, physical limitations, or difficulty using handheld inhalers benefit from a nebulized formulation, as it allows medication delivery without requiring hand-breath coordination or a forceful inhalation. This makes it a useful option for patients with poor inhaler technique or those transitioning from hospital care. Pharmacokinetically, revefenacin is delivered via nebulization, with peak effects typically observed within a couple of hours. Importantly, systemic absorption is relatively low, but elderly patients or those with hepatic impairment may be more susceptible to anticholinergic side effects. Clinically, revefenacin improves lung function, reduces COPD symptoms, and can decrease exacerbation frequency. Common adverse effects include cough, dry mouth, constipation, and urinary retention. Caution is advised in patients with narrow-angle glaucoma or prostatic hyperplasia due to its antimuscarinic properties. Revefenacin is not intended for acute bronchospasm or rescue therapy—it is strictly for long-term, once-daily maintenance.