POPULARITY
Categories
Send us a textThis episode features Dr. Giulia Lima (Boston Children's Hospital), a CHNC Mentored Fellow, discussing risk factors for morbidity and mortality among preterm infants with congenital heart disease (CHD) using data from over 11,000 NICU admissions. Surprisingly, older gestational age did not predict improved survival once infants survived beyond three days. Major mortality predictors included surgical NEC, bloodstream infection, trisomy 21, airway anomalies, and compromised systemic output lesions. Multiple gestation appeared protective, though reasons remain unclear. Dr. Lima highlights the importance of standardized prenatal steroids, care coordination, and exploring socioeconomic and ethnic disparities to improve outcomes in this uniquely vulnerable CHD population.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!
Todd Love, Psy.D., JD, explores the science linking ADHD and behavioral addictions — from gambling and pornography to gaming and social media. He explains the toll these behaviors take on daily life and highlights strategies that promote recovery. Behavioral Addictions and ADHD: Resources Free Download: Your ADHD Dopamine Menu Template Read: ADHD and Addiction: The Truth About Substance Abuse Read: Video Game Addiction: Signs, Risk Factors, and ADHD Links Read: Never Enough? Why ADHD Brains Crave Stimulation Access the video and slides for podcast episode #583 here: https://www.additudemag.com/webinar/behavioral-addiction-adhd/ Thank you for listening to ADDitude's ADHD Experts podcast. Please consider subscribing to the magazine (additu.de/subscribe) to support our mission of providing ADHD education and support.
The McCullough Report with Dr. Peter McCullough – A comprehensive new report from the McCullough Foundation reveals strong evidence linking early childhood vaccination to increased autism risk. Drawing on over a hundred studies, researchers challenge long-held assumptions about vaccine safety and call for urgent public health reforms, including suspension of vaccine mandates and a reexamination of the National Childhood...
The McCullough Report with Dr. Peter McCullough – A comprehensive new report from the McCullough Foundation reveals strong evidence linking early childhood vaccination to increased autism risk. Drawing on over a hundred studies, researchers challenge long-held assumptions about vaccine safety and call for urgent public health reforms, including suspension of vaccine mandates and a reexamination of the National Childhood...
Contributor: Meghan Hurley, MD Educational Pearls: 1. Initial Assessment Start with a physical examination: Determine if the bleed is anterior or posterior. Perform a primary survey: assess airway, breathing, and circulation (ABCs). Airway compromise = intubation immediately. If the patient is stable, have them blow out any clots, then re-examine the nares. 2. Topical Medications Anesthetics: provide local anesthesia and pain relief. Lidocaine Tetracaine Vasoconstrictors: reduce bleeding. LET (Lidocaine, Epinephrine, Tetracaine) is ideal because it provides anesthesia and vasoconstriction. Cocaine pledgets (less common). Tranexamic acid (TXA). Oxymetazoline (Afrin). Cautery (Chemical): If an anterior bleed is visualized, silver nitrate can be applied for cauterization 3. Technique Tips Use a nasal speculum. Spread up and down rather than side to side to avoid injury to the septum. Place LET-soaked gauze in the nares. Apply a nasal clamp for ~15 minutes to compress the vessels. Note that pledgets may cause upper lip numbness 4. Reassessment After 15 minutes, remove materials and inspect for a source of bleeding. If still bleeding and a source is identified, cauterize the site. Observe for 15 minutes to monitor for recurrence of bleeding. 5. Packing If the above measures fail to control bleeding: Anterior packing: Nasal tampon (Merocel) Convenient for outpatient removal. Balloon device Inflate the anterior balloon for compression. Posterior packing: More complex, should consult ENT for additional assistance. 6. Disposition & Follow-Up Although rare, toxic shock syndrome is a possible complication of nasal packing. Antibiotic prophylaxis is controversial, but may be considered in high-risk patients. Outpatient follow-up if stable: Tampon: The patient can remove it at home. Balloon: Return to ED for removal. 7. Risk Factors for Epistaxis & Prevention Deviated septum, dry environments, and anticoagulant use Advise on humidifier use, nasal saline, and medication review to minimize future episodes. References: Tunkel DE, Anne S, Payne SC, et al. Clinical Practice Guideline: Nosebleed (Epistaxis). Otolaryngology–Head and Neck Surgery. 2020;162(1_suppl):S1-S38. doi:10.1177/0194599819890327 Summarized by Ashley Lyons, OMS3 | Edited by Ashley Lyons and Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/
Send us a message with this link, we would love to hear from you. Standard message rates may apply.We break down osteopenia and osteoporosis with clear steps to protect independence: how bones weaken, how DEXA scoring works, and which daily habits reduce fracture risk. We share nutrition, exercise, lifestyle changes, and home safety that make a measurable difference.• key stats on fracture risk in women and men over 50• definitions of osteopenia and osteoporosis using T-scores• hip, spine and wrist as common fracture sites• why bone loss accelerates after menopause• risk factors including family history, smoking and low weight• DEXA scan basics and when to ask for screening• calcium and vitamin D targets and food sources• Mediterranean diet, protein and supportive micronutrients• weight-bearing, resistance and balance training essentials• Tai Chi and fall risk reduction• home safety changes that prevent falls• when medications like bisphosphonates or denosumab help• practical questions to ask your clinicianReferences1. Osteoporosis: Common Questions and Answers. Harris K, Zagar CA, Lawrence KV. American Family Physician. 2023;107(3):238-246.2. Postmenopausal Osteoporosis. Walker MD, Shane E. The New England Journal of Medicine. 2023;389(21):1979-1991. doi:10.1056/NEJMcp2307353.3. American Association of Clinical Endocrinologists/American College of Endocrinology Clinical Practice Guidelines for the Diagnosis and Treatment of Postmenopausal Osteoporosis-2020 Update. Camacho PM, Petak SM, Binkley N, et al. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 2020;26(Suppl 1):1-46. doi:10.4158/GL-2020-0524SUPPL.4. Global, Regional Prevalence, and Risk Factors of Osteoporosis According to the World Health Organization Diagnostic Criteria: A Systematic Review and Meta-Analysis. Xiao PL, Cui AY, Hsu CJ, et al. Osteoporosis International : A Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2022;33(10):2137-2153. doi:10.1007/s00198-022-06454-3.5. Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement. Curry SJ, Krist AH, Owens DK, et al. JAMA. 2018;319(24):2521-2531. doi:10.1001/jama.2018.7498.6. The Cost of Osteoporosis, Osteopenia, and Associated Fractures in Australia in 2017. Tatangelo G, Watts J, Lim K, et al. Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research. 2019;34(4):616-625. doi:10.1002/jbmr.3640.7. The Prevalence and Treatment Rate Trends of Osteoporosis in Postmenopausal Women. Zhang X, Wang Z, Zhang D, et al. PloS One. 2023;18(9):e0290289. doi:10.1371/journal.pone.0290289.8. Osteopenia: A Key Target for Fracture Prevention. Reid IR, McClung MR. The Lancet. Diabetes & Endocrinology. 2024;12(11):856-864. doi:10.1016/S2213-8587(24)00225-0.9. Effectiveness and Safety of Treatments to Prevent Fractures in People With Low Bone Mass or Primary Osteoporosis: A Living Systematic Review and Network Meta-Analysis for the American College of Physicians. Ayers C, Kansagara D, Lazur B, et al. Annals of Internal Medicine. 2023;176(2):182-195. doi:10.7326/M22-0684.Support the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski
Dr. Mary Maish discusses how a spontaneous pneumothorax or collapsed lung occurs, as well as risk factors and the latest treatment options.
In this episode of One in Ten, host Teresa Huizar talks with Dr. Matt Kafafian from George Washington University about his research on how the COVID-19 pandemic has reshaped the nature of the characteristics of exploited youth served by a Children's Advocacy Center. Dr. Kafafian discusses significant findings from studies examining post-pandemic changes in the identification and referral of commercially sexually exploited children and youth. They explore how shifts to online environments and evolving police and social service practices have impacted the demographics and types of exploitation cases being reported. Key points include the new challenges facing child abuse professionals, changes in risk factors, and the implications for screening tools designed to identify vulnerable youth. Dr. Kafafian also discusses emerging trends related to gender differences and mental health issues among exploited youth, highlighting the need for updated tools and approaches in the field. Time Stamps Time Topic 00:00 Introduction and Episode Overview 00:17 Guest Introduction: Dr. Matt Kavian 00:48 Impact of the Pandemic on Youth Exploitation 04:29 Pre-Pandemic Vulnerabilities and Risk Factors 06:53 Changes in Youth Exploitation During the Pandemic 08:39 Study Findings and Hypotheses 24:20 Implications for Child Abuse Professionals 26:35 Future Research Directions 29:17 Acknowledgments and Conclusion ResourcesChanging Profiles of Youth Referred for Commercial Sexual Exploitation before and since the Onset of COVID-19 in the United States - Matthew Kafafian, Ieke de Vries, Amy Farrell, Christen Asiedu, Elizabeth Bouchard, 2025Support the showDid you like this episode? Please leave us a review on Apple Podcasts.
Summary In this episode, Andy talks with Amireh Amirmazaheri, CEO of PMO Solutions and a leading voice in the global PMO community. From growing up in Iran during a time of war to building a respected consultancy in Australia, Amireh shares how resilience and curiosity shaped her approach to leadership and enabling project success. You'll hear how PMOs have evolved from administrative hubs to strategic influencers, what it means to truly "speak the language of executives," and how to recognize when a PMO is at risk of drifting into irrelevance. We also explore how AI is transforming the work of PMOs and what leaders can do to stay ahead of the curve. Plus, Amireh offers practical advice on leading as a woman in project management and applying PMO principles at home as a parent. If you're looking for insights on elevating PMO impact, executive communication, and leading through change, this episode is for you! Sound Bites "Limitations aren't always bad. They push us into the creativity zone." "Executives don't want red or amber. They want to know where the ship is heading." "When PMOs chase BAU firefighting, they lose their strategic brain." "If PMOs stay educated and ahead of the game, they can influence the AI journey." "It's okay to cry. Then think, learn, and lead." "Um, should I tell you that my little one has a kanban board?" Chapters 00:00 Introduction 01:31 Start of Interview 01:42 Early Life in Iran and Resilience 12:56 Lessons About Enablement 15:02 How PMOs Have Changed 18:55 Speaking the Language of Executives 21:22 Failure Clues and PMO Drift 25:11 Sponsorship as a Risk Factor 26:08 Using AI and Its Near-Term Impact on PMOs 32:25 Leading as a Woman 37:44 Applying PM and PMO Ideas at Home 40:22 PMO Global Alliance Overview 42:15 End of Interview 42:50 Andy Comments After the Interview 46:22 Outtakes Learn More You can learn more about Amireh and her work at PMOSol.com, or connect with her on LinkedIn. For more learning on this topic, check out: Episode 436 with Laura Barnard, about the IMPACT Engine Episode 429 with Bill Dow, about PMO insights Episode 187 with Peter Taylor, Bill Dow, and others, about the State of PMOs Level Up Your AI Skills Join other listeners from around the world who are taking our AI Made Simple course to prepare for an AI-infused future. Just go to ai.PeopleAndProjectsPodcast.com. Thanks! Pass the PMP Exam This Year If you or someone you know is thinking about getting PMP certified, we've put together a helpful guide called The 5 Best Resources to Help You Pass the PMP Exam on Your First Try. We've helped thousands of people earn their certification, and we'd love to help you, too. It's totally free, and it's a great way to get a head start. Just go to 5BestResources.PeopleAndProjectsPodcast.com to grab your copy. I'd love to help you get your PMP! Join Us for LEAD52 I know you want to be a more confident leader—that's why you listen to this podcast. LEAD52 is a global community of people like you who are committed to transforming their ability to lead and deliver. It's 52 weeks of leadership learning, delivered right to your inbox, taking less than 5 minutes a week. And it's all for free. Learn more and sign up at GetLEAD52.com. Thanks! Thank you for joining me for this episode of The People and Projects Podcast! Talent Triangle: Ways of Working Topics: PMOs, Executive Communication, Leadership, AI in Projects, Change Management, Strategic Thinking, Women in Leadership, Organizational Influence, Resilience, Stakeholder Engagement, Career Growth, Continuous Improvement The following music was used for this episode: Music: Brooklyn Nights by Tim Kulig License (CC BY 4.0): https://filmmusic.io/standard-license Music: Tuesday by Sascha Ende License (CC BY 4.0): https://filmmusic.io/standard-license
PodChatLive 203: Patients trust imaging more than clinicians, lower limb apophysitis incidence & risk factors, and The Centre for Podiatry HistoryContact us: getinvolved@podchatlive.comLinks from this episode:“It's hard to trust an individual, it's easier to trust an image”—patients with low back pain want imaging as a means of coping with uncertaintyIncidence of and Risk Factors for Lower Extremity Apophysitis in Children and Adolescents
In this episode of the Brain and Life podcast, co-host Dr. Katy Peters is joined by Dr. Laurel Cherian, an associate professor in the Department of Neurological Sciences at Rush University Medical Center and Assistant Dean of Advising, Medical Student Affairs for Rush Medical College to discuss stroke awareness, prevention, and treatment for World Stroke Day. They answer listener-submitted questions about stroke risk factors, symptoms, and recovery strategies, emphasizing the importance of recognizing stroke signs and maintaining a healthy lifestyle Additional Resources Get Smart about Stroke Navigating the Complexities of Stroke Stroke: Symptoms, Risk Factors, and Treatments Other Brain & Life Podcast Episodes on These Topics Matt and Kanlaya Cauli on Rebuilding Life After Stroke Timothy Omundson on Stroke Recovery and His Return to Television Peloton Instructor Bradley Rose on Returning to Life After Stroke We want to hear from you! Have a question or want to hear a topic featured on the Brain & Life Podcast? · Record a voicemail at 612-928-6206 · Email us at BLpodcast@brainandlife.org Social Media: Guests: Dr. Laurel Cherian @rushmedical Hosts: Dr. Daniel Correa @neurodrcorrea; Dr. Katy Peters @KatyPetersMDPhD
Drs Harrington, Rodriguez, and Ridker discuss the changing field of cardiac prevention, where imaging fits in, and the new concept of standard modifiable risk factor-less patients. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association https://doi.org/10.1161/CIR.0000000000001078 Development and Validation of the American Heart Association's PREVENT Equations https://doi.org/10.1161/CIRCULATIONAHA.123.067626 C-Reactive Protein and Cardiovascular Risk Among Women With No Standard Modifiable Risk Factors: Evaluating the 'Smurf-Less but Inflamed' https://doi.org/10.1093/eurheartj/ehaf658 Mortality in STEMI Patients Without Standard Modifiable Risk Factors: A Sex-Disaggregated Analysis of SWEDEHEART Registry Data https://doi.org/10.1016/S0140-6736(21)00272-5 Inflammation, Cholesterol, Lipoprotein(a), and 30-Year Cardiovascular Outcomes in Women https://www.nejm.org/doi/10.1056/NEJMoa2405182 Statins for the 'SMuRFLess But Inflamed': Silent Vascular Inflammation and the Challenge of Translational Science https://doi.org/10.1016/j.jacbts.2025.101318 VERVE-101: A Promising CRISPR-Based Gene Editing Therapy That Reduces LDL-C and PCSK9 Levels in HeFH Patients https://academic.oup.com/ehjcvp/article/10/2/89/7492807 You may also like: Hear John Mandrola, MD, give a summary and his perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net
Dementia is a major challenge for the NHS, with one in six people in their eighties developing the condition. For many people, fear and stigma surrounds the condition, so the GP's role as the first port of call is crucial.In this episode of the Clinical Update podcast, MIMS Learning's Rhiannon and Sangeeta draw on the expertise of MIMS Learning's professional clinical writers and speakers to discuss how primary care can approach the initial assessment process, key differentials such as delirium and depression, and important modifiable risk factors, including hearing loss.This episode also covers the challenge of 'therapeutic nihilism', latest research on antipsychotic use, and practical approaches to polypharmacy in patients with cognitive impairment.Educational objectivesAfter listening to this podcast, healthcare professionals should be better able to:Describe the GP's role in the initial assessment of suspected dementia, including history taking and cognitive assessment tools.Distinguish presentations of dementia from key differentials, including delirium and depression.Recall key modifiable risk factors for dementia, such as smoking, social isolation, and unmanaged hearing loss.Understand the risks associated with antipsychotic use in people with dementia and NICE recommendations for their use.Recognise 'therapeutic nihilism' and how primary care can support patients and carers through positive language and use of social prescribing.Apply a structured approach to medication reviews for patients with dementia.PresentersRhiannon AshmanDeputy editor, MIMS LearningSangeeta KrishnanMedical editor, MIMS LearningYou can access the website version of this podcast, along with a list of key learning points, on MIMS Learning - and make notes for your appraisal. MIMS Learning offers hundreds of hours of CPD for healthcare professionals, along with a handy CPD organiser.Please note: this podcast is presented by medical editors and discusses educational content written or presented by doctors, nurses and other healthcare professionals on the MIMS Learning website and at live events.MIMS LearningSubscribe to MIMS LearningGuidance update: SIGN guidelines for support of people with dementia and their carersDelirium: clinical reviewCase series: polypharmacy in older people with mental health conditions Hosted on Acast. See acast.com/privacy for more information.
Episode topics: arm injuries, a food-for-thought World Series viewing assignment, and new research on UCL injury risk factors In anticipation of Dr. Glenn Fleisig's guest appearance on my next podcast, his most recent elbow injury research is discussed. We wrap up the Coaching the Coaches series and finish with a food-for-thought observation assignment for you during this week's games. Email Angel at angel@gymscience.com https://AngelBorrelliPitching.com
Send us a textRisk factors associated with the development of necrotizing enterocolitis in preterm infants on an exclusive human milk diet: a single-center case-control study.Ailumerab H, Miller JL, DeShea L, Beasley WH, Chaaban H, Bergner EM.J Perinatol. 2025 Aug 30. doi: 10.1038/s41372-025-02401-2. Online ahead of print.PMID: 40885806Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!
CoROM cast. Wilderness, Austere, Remote and Resource-limited Medicine.
This week, Aebhric talks with Jason Jarvis, a former Special Forces medic and current PhD candidate, and discusses Chagas disease, a tropical disease transmitted by the kissing bug. He explains the life cycle of the bug, the transmission of the disease, its clinical presentation, and the challenges in diagnosis and treatment. The conversation emphasises the importance of awareness and preventive measures, especially as Chagas disease is spreading to new regions, including parts of the United States. The discussion concludes with key take-home messages for healthcare providers and the need for ongoing education in tropical medicine.TakeawaysChagas disease is transmitted by the kissing bug, primarily in Central and South America.The life cycle of the kissing bug involves several stages, including the transmission of the parasite through its faeces.Clinical diagnosis is essential, especially in endemic areas where the disease is prevalent.The acute phase of Chagas disease is easier to treat than the chronic phase, which can lead to severe complications.Preventive measures include avoiding exposure to kissing bugs and ensuring blood products are screened for the disease.Chagas disease can also be transmitted through blood transfusions and organ transplants.Healthcare providers should be aware of the symptoms and risk factors associated with Chagas disease.The disease is now spreading to parts of the continental US, raising public health concerns.Ongoing education and awareness of tropical diseases are crucial for healthcare providers.The conversation highlights the importance of understanding the global health implications of diseases like Chagas. Chapters00:00 Introduction to Chagas Disease and Its Relevance02:36 Life Cycle of the Kissing Bug and Transmission of Chagas Disease04:58 Understanding the Pathophysiology of Chagas Disease07:31 Clinical Presentation and Diagnosis of Chagas Disease10:18 Chronic Phase and Long-term Effects of Chagas Disease12:41 Treatment Options and Challenges in Managing Chagas Disease14:51 Preventive Measures and Risk Factors for Chagas Disease17:39 Chagas Disease in the Context of Global Health19:42 Take-Home Messages for Healthcare Providers22:20 Future Considerations and Closing Thoughts
n the News.. COVID-19 & T1D, Ozempic Pill Progress, Faster Insulin, “Beyond Misconceptions,” and More It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: A new study looks at the link between COVID-19 and very young children, Lilly moves ahead with their Ozempic oral pill, ultra-rapid insulin clears another hurdle, Beyond Type 1 launches a new campaign and more! Find out more about Moms' Night Out Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX https://www.scientificamerican.com/article/advances-in-type-1-diabetes-science-and-tech/ This article is part of “Innovations In: Type 1 Diabetes,” an editorially independent special report that was produced with financial support from Vertex. XX More evidence linking COVID 19 to type 1 diabetes.. but still exactly why is a mystery. During the COVID-19 pandemic, there was an unexpected increase in the number of cases of type 1 diabetes in Sweden, particularly among children under 5 and young adult men. The infection accelerated the onset of diabetes among children between the ages of 5 and 9. The researchers looked at data from a 17-year period on the incidence of type 1 diabetes among all people under the age of 30 in Sweden. In addition, they compared the risk of developing diabetes among 720,000 individuals with positive COVID-19 tests against a control group of 3.5 million people. The findings are published in the journal Diabetologia. The number of diabetes cases increased by 12% in 2021 and 9% in 2022 compared with previous years. In 2023, the number of cases was back to a normal level. Despite this, the researchers cannot distinguish a clear connection between COVID-19 infection and diabetes, except for children between 5 and 9 years old. They had an increased risk of type 1 diabetes about one month after a COVID-19 infection even though their total risk did not increase. "However, it's clear that the COVID-19 vaccine can be ruled out as a cause of the increase in diabetes cases. The recommendation for the age group where we saw the strongest increase was not to get vaccinated. In addition, other studies on adults have shown that vaccination reduces the risk of developing type 1 diabetes after a COVID infection." https://medicalxpress.com/news/2025-10-diabetes-young-people-pandemic.html XX A new gene therapy approach aimed at protecting people with type 1 diabetes from developing diabetic kidney disease—a serious and common complication of the condition, has shown promising results in a University of Bristol study. Findings from this new study, published in Molecular Therapy, demonstrated a 64% reduction in a damage indicator for kidney disease, paving the way for a potential new treatment. The study, explored the potential of delivering a protein called VEGF-C directly into kidney cells. Previous studies have shown VEGFC could protect against kidney disease as it helps keep blood vessels in the kidney filter healthy, repairing early signs of diabetes-related kidney damage. https://medicalxpress.com/news/2025-10-gene-therapy-kidney-disease-diabetes.html XX The FDA has agreed to consider Afrezza inhaled insulin for children and teens. The company said in August that it submitted a supplemental Biologics License Application (sBLA) for Afrezza in the pediatric population and it's been assigned a decision deadline date of the end of May, 2026. Afrezza first recieved FDA approval for adults (age 18 and up) in June 2014 https://www.drugdeliverybusiness.com/fda-accepts-application-mannkind-inhaled-insulin-kids/ Update on inhaled insulin for kids.. in the open-label, randomized, phase 3 INHALE-1 clinical trial Afrezza demonstrated safe and effective replacement for rapid-acting meal insulin in children with type 1 diabetes (T1D and demonstrates comparable glycemic control to injected rapid-acting insulin. The INHALE-1 clinical trial assessed the safety and efficacy of Afrezza among children and adolescents with T1D, including a total of 230 patients aged 4 to 17 years. Researchers used basal injected insulin and randomly assigned inhaled insulin or rapid-acting analogue for meals, evaluating the change in hemoglobin A1c levels at 26 weeks. After completing 26 weeks of randomly assigned treatment with either Afrezza or rapid-acting insulin injections combined with basal insulin, participants continued receiving the inhaled insulin until week 52 for an extension phase to evaluate the safety and effectiveness of Afrezza with continued use.1,2 https://www.pharmacytimes.com/view/inhaled-insulin-demonstrates-comparable-safety-lung-function-and-efficacy-to-injectable-insulin-in-type-1-diabetes XX Eli Lilly released the results of two new Phase 3 trials of an experimental GLP-1 pill that the company says could become a “foundational treatment” for type 2 diabetes. The Indianapolis-based drugmaker plans to submit global regulatory applications for orforglipron in the treatment of type 2 diabetes next year. The company said it will seek approval of the drug as an obesity medication by the end of 2025. Lilly is trying to build on the success of its Mounjaro/Zepbound franchise by offering patients a pill instead of an injection. But the company is trailing behind rival Novo Nordisk in developing an oral alternative, and data released so far has raised some skepticism among investors. A study released in August showed that orforglipron could help patients lose an average of about 12% of their body weight. Wall Street had been expecting more; Lilly's injectable drug Zepbound produced weight loss of as much as 21%, and Novo Nordisk has achieved 15% weight loss percentages for both oral and injectable versions of its Wegovy medication. https://www.fiercebiotech.com/biotech/eli-lillys-orforglipron-bests-farxiga-padding-oral-glp-1-case-pair-phase-3-diabetes-wins XX XX UF Health Cancer Center researchers have found a surprising culprit behind common health problems such as obesity, diabetes and fatty liver disease: silent genetic glitches in the blood system that occur naturally as people age. The findings, published in the Journal of Clinical Investigation, mean that in the future, simple blood tests could be developed to identify people most at risk early on, helping prevent chronic illnesses and cancer through strategies like diet or lifestyle changes. As people age, stem cells in the bone marrow that produce blood cells gradually accumulate mutations in their DNA. Most mutations don't cause any issues, but sometimes blood stem cells with a mutation can start crowding out their peers. Called clonal hematopoiesis, this condition affects about 10% of older people and is associated with an increased risk of blood cancers like leukemia. It's also linked to a higher risk of obesity and diabetes. But the prevailing thinking was that obesity and related conditions promoted blood cell changes, not the other way around. The new study reverses that. The implications could be far-reaching, particularly as obesity has now overtaken smoking as the most significant and preventable risk factor for cancer. The team is studying how the mutations drive disease. Next, they plan to test how drugs like those commonly used to treat diabetes and new popular weight loss drugs might help reverse or prevent diseases caused by blood cell changes. https://medicalxpress.com/news/2025-10-hidden-blood-mutations-obesity-diabetes.html XX A new ultra rapid insulin continues to move forward. A phase 3 clinical trial of BioChaperone Lispro (liss-pro) conducted in China found it safe and effective compared with Humalog along with a significant reduction of the rise of blood glucose after a test meal. These results complete and confirm the positive outcomes previously obtained with THDB0206 injection in people with Type 2 Diabetes It combines Adocia's proprietary BioChaperone® technology with insulin lispro, the active ingredient in the standard of care, Humalog® (Eli Lilly). This innovative formulation acts significantly faster https://pharmatimes.com/news/ultra-rapid-insulin-shows-promise-in-phase-3-trial-for-type-1-diabetes/ Poor blood sugar control in adolescent patients with type 1 diabetes (T1D) may be associated with a higher risk of neuropathy in adulthood, according to recent research from the University of Michigan.1 The study included children diagnosed with T1D between 1990-1992 who were recruited into the Cognition and Longitudinal Assessment of Risk Factors over 30 Years cohort study in Australia. Investigators collected HbA1c from medical records, and microvascular complications were assessed through self-reports, clinical screenings, retinal photographs, and urinary albumin-creatinine testing.3 A total of 30 children were recruited from the original cohort with a mean diagnosis age of 2.9 years. After an average of 29.7 years (standard deviation [SD]: 3.9 years), 33% of participants (n = 13) developed neuropathy, 63% (n = 19) developed diabetes-related eye disease, and 10% (n = 3) developed neuropathy.3 Mean HbA1c estimates during adolescence (9% [74.9 mmol/mol]; 95% CI, 8.6-9.3 [70.5-78.1]) were substantially higher than childhood (8.2% [66.1 mmol/mol]; 95% CI, 7.8-8.5 [61.7-69.4]; P
Get your free 5-step plan for hearing loss diagnosis and treatment: click here Hearing loss affects 1 in 5 people globally, increases the risk of developing dementia, and has no cure. An astonishing half a billion people have hearing loss, which impacts their ability to communicate and connect with others. Hearing loss cases are increasing fast, especially among younger people. For many, hearing aids and cochlear implants can be life-changing, but they can't help everyone. But there is hope: Scientists around the world have been working tirelessly to develop NEW treatments for hearing loss. In this episode, Jonathan speaks to Dr. Marcelo Rivolta, a professor of sensory stem cell biology at Sheffield University. He's on the cusp of a major breakthrough that could mean hearing loss becomes a thing of the past. What you'll learn: Why hearing loss is becoming more common The shocking link between hearing loss and a 500% increased risk of dementia How modern headphones and loud concerts cause permanent, irreversible damage Why hearing loss can be more isolating than blindness The simple ways you can protect your hearing today How current technologies like hearing aids and cochlear implants work About the groundbreaking new science that could cure deafness using stem cells About Marcelo Rivolta Marcelo Rivolta is a Professor of Sensory Stem Cell Biology at the University of Sheffield. For over two decades, his research has focused on the use of human stem cells for the understanding and treatment of hearing loss. His lab was the first to demonstrate that it was possible to create both auditory hair cells and neurons from stem cells, and his pioneering work is now moving towards clinical trials in humans. Timecodes: 00:00 Introduction 00:26 Does hearing loss only affect older adults? 03:37 Is permanent hearing loss reversible? 06:03 At what volume do headphones start to cause hearing loss? 08:26 Why hearing loss is more isolating than blindness 09:41 The shocking link between hearing loss and dementia 12:00 Can hearing aids reduce your dementia risk? 13:13 How do we hear? A simple explanation 15:15 Why is your microphone just like your ear? 18:07 What goes wrong in your ear to cause hearing loss? 19:20 The cells in your body you're born with that have to last a lifetime 20:51 Why does loud noise cause irreversible damage? 23:15 Do hearing aids solve hearing loss for everybody? 24:08 The difference between a hearing aid and a cochlear implant 26:20 Is the hearing from a cochlear implant natural? 32:25 Can we find a cure for hearing loss? 34:15 Using stem cells to create new hearing cells 37:32 Can we reverse deafness? Groundbreaking study in animals 38:45 When will a cure for hearing loss be available? 42:25 What is auditory neuropathy? 45:06 What is tinnitus and could this research cure it? 46:46 Top tips to protect your hearing 50:03 Jonathan's summary Episode transcripts are available here: https://zoe.com/learn/category/podcast
In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden interviews Khoshal Latifzai, who transitioned from emergency medicine to regenerative medicine. They discuss the challenges of traditional medical practices, the importance of patient-centered care, and the innovative approaches in longevity and health optimization, including stem cell therapy. Koshal shares insights on the impact of genetics on athletic performance and the significance of understanding patient needs to minimize health risks. The conversation highlights the future of health technologies and the potential for optimizing health and longevity. For Audience · Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ ! Takeaways Khoshal transitioned from emergency medicine to regenerative medicine for a more fulfilling practice. Patient interactions in emergency medicine were limited and unsatisfying. Building a patient-centric practice allows for deeper connections and better care. Removing insurance from the equation can enhance patient engagement and satisfaction. Understanding risk factors is crucial for effective health optimization. Stem cell therapy is evolving with a focus on using patients' own cells. Athletes may face health issues due to overtraining and genetics. Innovations in health technologies are paving the way for longevity. The aging process can be viewed as a mosaic of different ages. Optimizing health today is essential for a better future. Chapters 00:00 Introduction to Regenerative Medicine 03:10 Transition from Emergency Medicine to Regenerative Medicine 05:55 Building a Patient-Centric Practice 09:01 Approach to Longevity and Health Optimization 11:47 Understanding Patient Needs and Risk Factors 15:05 Innovations in Stem Cell Therapy 18:07 The Role of Genetics in Athletic Performance 21:06 Navigating Overtraining and Health 23:59 The Future of Longevity and Health Technologies To learn more about Khoshal Latifzai: Website: rmrmco.com Instagram: @rmrmboulder Facebook: facebook.com/RMRMBoulder Got a question for Dr. Gladden? Submit it using the link below and it might be answered in our next Q&A episode! https://form.typeform.com/to/tIyzUai7? Reach out to us at: Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options. Use of information from this podcast and any linked materials is at the listener's own risk. Podcast Guest Disclosures Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team. Sponsorships & Affiliate Disclosures To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes. We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented. Additional Note on Content Integrity All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.
The Immigration Lawyers Podcast | Discussing Visas, Green Cards & Citizenship: Practice & Policy
In Episode 429 of the Immigration Lawyers Toolbox® Podcast, host John Q. Khosravi, Esq. sits down with Nick Pardini, financial analyst and founder of Davos Global, to discuss investment-based immigration, global economic trends, and what investors should know before pursuing E-2 and EB-5 visas. Nick shares his deep insight into emerging markets, foreign investment flows, and how U.S. immigration policy intersects with global finance. Together, John and Nick explore how attorneys can better serve investor clients by understanding both the legal framework and economic realities shaping investment migration today.
Dr. Allison Zielinski, cardiology at Northwestern Medicine Bluhm Cardiovascular Institute, joins John Williams to talk about the importance of getting your heart health checked, why you should know your risk factors, and the most common signs of a heart attack. What are the symptoms that we should be aware of?
Dr. Allison Zielinski, cardiology at Northwestern Medicine Bluhm Cardiovascular Institute, joins John Williams to talk about the importance of getting your heart health checked, why you should know your risk factors, and the most common signs of a heart attack. What are the symptoms that we should be aware of?
Dr. Allison Zielinski, cardiology at Northwestern Medicine Bluhm Cardiovascular Institute, joins John Williams to talk about the importance of getting your heart health checked, why you should know your risk factors, and the most common signs of a heart attack. What are the symptoms that we should be aware of?
QFF: Quick Fire Friday – Your 20-Minute Growth Powerhouse! Welcome to Quick Fire Friday, the Grow A Small Business podcast series that is designed to deliver simple, focused and actionable insights and key takeaways in less than 20 minutes a week. Every Friday, we bring you business owners and experts who share their top strategies for growing yourself, your team and your small business. Get ready for a dose of inspiration, one action you can implement and quotable quotes that will stick with you long after the episode ends! In this episode of Quick Fire Friday, host Rob Cameron interviews Nic McGrue, founder of Polymath Legal, reveals how he helps real estate investors and business owners legally raise capital while protecting their interests under U.S. securities laws. He shares insights on common mistakes to avoid, the importance of proper legal documentation, and how strategic compliance can unlock growth opportunities. Nic also highlights inspiring success stories, including turning around a family-owned winery and helping a client expand from 30 single-family homes to over 800 multifamily units. This episode is packed with practical, real-world advice for anyone serious about raising funds the right way and building lasting generational wealth. Key Takeaways for Small Business Owners: Organize your finances early – Clean, accurate financials make you more credible and attractive to investors. Start networking before you need capital – Build relationships and trust so investors are ready when opportunities arise. Understand securities laws – Know the legal side of raising funds to avoid costly compliance mistakes. Our hero crafts outstanding reviews following the experience of listening to our special guests. Are you the one we've been waiting for? Assemble a strong support team – Partner with skilled legal, financial, and underwriting professionals for smoother deals. Disclose risks honestly – Transparent communication builds investor confidence and protects you legally. Plan for growth, not just funding – Focus on long-term strategy, scalability, and creating generational wealth through smart investments. One action small business owners can take: According to Nic McGrue, one action small business owners can take is to get their financials in order — by maintaining clean, accurate records and proper documentation, they can build investor confidence and be fully prepared when it's time to raise capital. Do you have 2 minutes every Friday? Sign up to the Weekly Leadership Email. It's free and we can help you to maximize your time. Enjoyed the podcast? Please leave a review on iTunes or your preferred platform. Your feedback helps more small business owners discover our podcast and embark on their business growth journey.
Kara Vavrosky, RDHEP, sat down with Dr. Kim Milleman, a hygienist and researcher, and Dr. Kumar Shah, prosthodontist and professor of clinical dentistry at UCLA, where they discussed the risk factors for periodontal disease and the adjunctive role of mouthrinse.A big thank you to LISTERINE® for sponsoring this video and for being such a champion of clinical research.Learn more about the impact of diabetes on oral health at https://kenvuepro.com/en-us/clinical-resources/diabetes-oral-health-connectionNeed CE? Start earning CE credits today at https://rdh.tv/ceGet daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Jeremy Maldonado breaks down cybersecurity fundamentals from a real-world IT operations perspective. From phishing and social engineering to patching best practices and zero trust, Jeremy shares practical insights to help you protect your organization — starting with your own behavior.He covers:Why the human factor is still your biggest vulnerabilityThe basics of zero trust in everyday communicationSocial engineering red flags to watch forHow to think strategically about patch prioritizationWhy most orgs still struggle with timely patchingTips for human-controlled automation using the Automox consoleWhether you're new to cybersecurity or want to tighten your patching strategy, this episode gives you a tactical refresh on where to focus your attention.
In this episode, Holly Niven and Taya Forde speak with Euan Bennet, Lecturer in Research and Numerical Skills at the University of Glasgow and expert in risk factor analysis in Equine Sports. He introduces us to common fatal horse racing injuries and talks about his most recent paper https://doi.org/10.1111/evj.14503 where he uncovered novel risk factors […]
Send us a textUnderstanding the Sacroiliac Joint: Causes, Diagnosis, and TreatmentIn this episode of PTs Snacks podcast, we cover the often misunderstood sacroiliac (SI) joint, explaining its anatomy and function. Listeners will learn about the causes of SI joint pain and the risk factors associated with it. We also discuss methods for diagnosing SI joint pain and effective treatments.00:00 Introduction to PTs Snacks Podcast00:58 Overview of the Sacroiliac (SI) Joint01:28 Anatomy and Function of the SI Joint02:59 Causes and Risk Factors of SI Joint Pain04:13 Symptoms and Differential Diagnosis06:48 Provocative Tests for SI Joint Pain09:31 Imaging and Injections for Diagnosis10:43 Treatment Options for SI Joint Pain11:32 Conclusion and Additional ResourcesResources:Nejati P, et al. Effectiveness of exercise therapy and manipulation on sacroiliac joint dysfunction: a randomized controlled trial. Pain Physician. 2019;22(1):53-61.Trager R, et al. Efficacy of manual therapy for sacroiliac joint pain syndrome: a systematic review and meta-analysis of randomized controlled trials. Musculoskelet Sci Pract. 2024;67:102815.Doğan N, et al. Effects of mobilization treatment on sacroiliac joint dysfunction syndrome. Pain Res Manag. 2021;2021:6613629.Javadov A, et al. The efficiency of manual therapy and sacroiliac and lumbar exercises in patients with sacroiliac joint dysfunction syndrome. Turk J Phys Med Rehabil. 2021;67(2):129-36.Cerasoli T, et al. Injective therapies for managing sacroiliac joint pain in spondyloarthropathy: a systematic review and meta-analysis. 2025.Gartenberg A, et al. Sacroiliac joint dysfunction: pathophysiology, diagnosis, and treatment. Curr Rev Musculoskelet Med. 2021;14(6):414-21.Liu Y, et al. Comparative efficacy of clinical interventions for sacroiliac joint pain: systematic review and network meta-analysis with preliminary design of treatment algorithm. Pain Physician. 2023;26(2):123-34.Polly D, et al. Two-year outcomes from a randomized controlled trial of minimallGo to PT Final Exam using this link to access great studying options to conquer the NPTE!Support the showStay Connected! Make sure to hit follow now so you don't miss an episode! Got questions? Email me at ptsnackspodcast@gmail.com or leave feedback HERE. You can also join the email list HERE Need CEUs Fast?Time and resources short? Medbridge has you covered: Get over $100 off a subscription with code PTSNACKSPODCAST: Medbridge Students: Save $75 off a student subscription with code PTSNACKSPODCASTSTUDENT—a full year of unlimited access for less! Prepping for the NPTE? Get all the study tools you need to master it at PT Final Exam. Use code PTSnacks at checkout to get a discount! Want to Support the Show?Help me keep creating free content by: Sharing the podcast with someone who'd benefit. Contributing directly via the link...
Welcome to the Urban Property Investor! In "The Risk Factor," we unpack the complexities of real estate investment. Learn to navigate common pitfalls, understand hidden costs, and think long-term. We'll explore tools like the Kelly Criterion, compare new vs. established properties, and tackle market risks and investment psychology. Discover why a low-risk strategy is key to sustainable wealth in real estate. Tune into episode 273 now! I discuss - 00:00 - Introduction to Real Estate Investment 03:04 - Understanding Risk in Real Estate 05:47 - The Importance of Long-Term Thinking 08:25 - Evaluating Property Value and Hidden Costs 11:07 - The Kelly Criterion and Risk Assessment 14:14 - New vs. Established Properties 17:05 - Market Risk and Its Implications 19:49 - Delivery Risk in Real Estate Investment 22:29 - Behavioural Finance and Risk Tolerance 25:01 - Strategies for Successful Real Estate Investment 27:41 - Conclusion and Key Takeaways Don't hesitate to hit me up on Facebook @SamSaggers. DM me with any of your questions :) If you're yet to subscribe, be sure to do so on your favourite channel. Apple - https://pre.fyi/upi-apple Spotify - https://pre.fyi/upi-spotify YouTube - https://pre.fyi/upi-youtube And remember, I'm really good on 1.25 or 1.5 speed :) Take care, Sam Hey Investors! It's great to see you here. To get you started on your journey we've popped a few educational resources below for FREE! ➡️ DOWNLOAD The Part Time Property Investor ebook-https://pre.fyi/yt-part-time-investor-ebook ➡️ DOWNLOAD The Property Investor's Cashflow Calculator- https://pre.fyi/yt-cashflow-calculator ➡️ REGISTER for a Property Investing Webinar - https://positivere.events/learn-to-invest Positive Real Estate's Property Investor Masterclass
Interview with Helen Kim, PhD, author of Risk of Future Hemorrhage From Unruptured Brain Arteriovenous Malformations: The Multicenter Arteriovenous Malformation Research Study (MARS). Hosted by Cynthia E. Armand, MD. Related Content: Risk of Future Hemorrhage From Unruptured Brain Arteriovenous Malformations
Interview with Helen Kim, PhD, author of Risk of Future Hemorrhage From Unruptured Brain Arteriovenous Malformations: The Multicenter Arteriovenous Malformation Research Study (MARS). Hosted by Cynthia E. Armand, MD. Related Content: Risk of Future Hemorrhage From Unruptured Brain Arteriovenous Malformations
We review the diagnosis, risk stratification, & management of acute pulmonary embolism in the ED. Hosts: Vivian Chiu, MD Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Acute_Pulmonary_Embolism.mp3 Download Leave a Comment Tags: Pulmonary Show Notes Core Concepts and Initial Approach Definition: Obstruction of pulmonary arteries, usually from a DVT in the proximal lower extremity veins (iliac/femoral), but may be tumor, air, or fat emboli. Incidence & Mortality: 300,000–370,000 cases/year in the USA, with 60,000–100,000 deaths annually. Mantra: “Don't anchor on the obvious. Always risk stratify and resuscitate with precision.” Risk Factors: Broad, including older age, inherited thrombophilias, malignancy, recent surgery/trauma, travel, smoking, hormonal use, and pregnancy. Clinical Presentation and Risk Stratification Presentation: Highly variable, showing up as anything from subtle shortness of breath to collapse. Acute/Subacute: Dyspnea (most common), pleuritic chest pain, cough, hemoptysis, and syncope. Patients are likely tachycardic, tachypneic, hypoxemic on room air, and may have a low-grade fever. Chronic: Can mimic acute symptoms or be totally asymptomatic. Pulmonary Infarction Signs: Pleuritic pain, hemoptysis, and an effusion. High-Risk Red Flags: Signs of hypotension (systolic blood pressure < 90 mmHg for over 15 minutes),
Send us a textIn this episode, I had the pleasure of speaking with Dr Isabella Eiler from the Medical College of Wisconsin, Milwaukee, Wisconsin. She is originally from the Milwaukee area and first attended the Medical College of Wisconsin for medical school. She then went on to complete her pediatric residency at the Indiana University School of Medicine. In this episode of Rupa's Fellows Friday, Dr. Isabella Eiler discusses her journey in neonatology, particularly her interest in NeuroNICU and hypoxic ischemic encephalopathy (HIE). She shares insights from her research on missed opportunities for neonatal assessments and the importance of multidisciplinary collaboration in improving patient care. Dr. Eiler emphasizes the significance of mentorship during fellowship and the impact of social determinants on neonatal follow-up care. She also reflects on the challenges faced in research and offers valuable advice for future neonatology fellows. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!
Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Trends in Risk Factor Prevalence and Incidence of Acute Myocardial Infarction in Young Adults.
Each year, more than 20 million people worldwide are diagnosed with cancer—an already high number that is expected to increase...[…]
Each year, more than 20 million people worldwide are diagnosed with cancer—an already high number that is expected to increase...
Dr Ankur Vermur sees heart attack patients daily in his emergency room in New Delhi, India, almost all of them with normal cholesterol levels. We discuss the key, underappreciated metabolic risk factors for aetherosclerosis (ASCVD) and how you can avoid them with lifestyle changes.SUPPORT MY WORK
Tommy John is a name associated with the game of baseball not just because of the pitcher's Hall of Fame career, but because it has become synonymous with a devastating injury to the Ulnar Collateral Ligament of the elbow that continues to plague baseball pitchers often resulting in reconstructive surgery colloquially known as the Tommy John Surgery. Multiple risk factors have been postulated to put the UCL at risk of rupture including increased velocity, torque across the elbow, baseline stiffness in the shoulder and/or elbow, pitch volume, and pitch type. Well known for their extensive work in baseball science, Dr. Glenn Fleisig, PhD from the famed American Sports Medicine Institute in Birmingham, AL and Dr. Peter Chalmers, MD from the University of Utah in Salt Lake City join us to discuss their study that looks at these risk factors in professional baseball pitchers.
Susan shares her deeply personal connection to breast cancer, having both lost grandmothers to the disease and supporting her sister through her own diagnosis. Drawing from years of experience in healthcare and her own journey navigating high-risk screenings, Susan gets candid about the gaps in breast health education, especially around dense breast tissue, and underscores the importance of self-advocacy, persistence, and community support. Together, Lisa and Susan break down the barriers that so many women face, discussing why knowing your breast density matters, why speaking up in the doctor's office can be lifesaving, and the simple yet powerful actions—like sharing information and writing to lawmakers—that can make a difference. Whether you're a survivor, advocate, healthcare professional, or just searching for honest conversations about women's health, this episode is packed with insight, hope, and practical advice for taking charge of your wellbeing. So grab a cup, tune in, and join us on the path toward early detection, empowered choices, and a community dedicated to women's health equity. TIMESTAMPS: 00:00 Clear Voices: Breast Cancer Stories 04:20 Discovering Dense Breast Awareness 07:20 Importance of Advanced Breast Screening 12:04 Self-Advocacy in Women's Health 13:56 "Consider Ultrasound for Breast Density" 19:04 "Empowering Women: Support and Voice" 20:54 Reevaluating Hormone Replacement Therapy 25:21 Empowering Women in Healthcare Innovation 29:05 Empowering Survivors' Voices in Advocacy 30:23 Heartfelt Stories & Support Advocacy 35:13 "Dense Breast Tissue Risk Factor" 37:11 Empowering Advocacy and Community Support Susan Willig, CEO True North Accomplished and creative marketing executive with cross-industry experience (medical device, education, information services and technology). Proven and accomplished career of exceeding business objectives by creating relevant brand strategy and translating to effective marketing plans and through to execution. I build meaningful and lasting customer experiences and relationships to increase brand equity and revenue. As a strong leader and team builder both inside and outside the company, I create a consistent meaningful global experience for customers, while being mindful of regional nuances. Follow Susan: LinkedIn: https://www.linkedin.com/in/susanwillig/ Website: https://www.truenorthsw.com/ Learn More About The Clear Pathways Program: https://www.breastdensitysummit.org/ Follow Lisa Malia: LinkedIn: https://www.linkedin.com/in/lisamalianorman/ Instagram: https://www.instagram.com/lisamalia.evoke/ Feminine Leadership Community: https://circle.lisamalia.co/join?invitation_token=4aa1b4081e801124df7210b1a84e18ecfbbd2e21-7b7ac858-46a9-47ff-b281-514108ce92d8 Write your representative with pre drafted letters on current topic at Women's Health Advocates: https://womenshealthadvocates.org/write-to-congress/#/
Dr. Kelly Arps, Dr. Naima Maqsood, and Dr. Sahi Allam discuss modifiable risk factors and lifestyle management of atrial fibrillation with Dr. Prash Sanders. Atrial fibrillation is becoming more prevalent across the world as people are living longer with cardiovascular disease. While much of our current focus lies on the pharmacological and procedural management of atrial fibrillation, several studies have shown that targeted reduction of risk factors, such as obesity, sleep apnea, hypertension, and alcohol use, can also significantly reduce atrial fibrillation burden and symptoms. Today, we discuss the data behind lifestyle management and why it is considered the “4th pillar” of atrial fibrillation treatment. We also explore ways to incorporate prevention strategies into our general cardiology and electrophysiology clinics to better serve the growing atrial fibrillation population. Audio editing for this episode was performed by CardioNerds Intern, Julia Marques Fernandes. CardioNerds Atrial Fibrillation PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls More people have atrial fibrillation because it is being detected earlier using wearable technology, and patients are living longer with subclinical or clinical cardiovascular disease There are 3 components of atrial fibrillation: an electrical “trigger” + a susceptible substrate (due to age, sex, genetics) + “perpetuators” that cause the trigger to continue stimulating the substrate (lifestyle risk factors such as obesity, smoking, diabetes, etc.) Obesity is the highest attributable risk factor for atrial fibrillation. Treating obesity often helps to treat other risk factors, such as hypertension and sleep apnea. Counseling is patient-dependent. Most patients are unable to make major behavioral changes cold-turkey and will need to make small, incremental changes. Dr. Sanders' tip: He tells his own patients that “atrial fibrillation is the body's response to stress.” The key to treating atrial fibrillation is to control your underlying stressors - procedures and medications are simply band-aids that do not fix the root of the problem. Notes Notes drafted by Dr. Allam. 1. How common is atrial fibrillation? Atrial fibrillation is the most common sustained arrhythmia. Currently, an estimated 50-60 million individuals worldwide are estimated to have atrial fibrillation, or roughly 1 in 4 individuals over the age of 45.1 The rising global prevalence of atrial fibrillation can be attributed to the aging of the population, increased rates of obesity, and greater accumulation of cardiovascular risk factors and survival with clinical cardiovascular disease.2 Atrial fibrillation is also being detected earlier through digital and wearable devices.2 Annually, we spend approximately $5,312 per adult on the management of atrial fibrillation in the United States.3 2. What is the underlying pathophysiology of atrial fibrillation? How do risk factors like sleep apnea or obesity “trigger” atrial fibrillation? For atrial fibrillation to occur, there is an electrical “trigger”, a susceptible substrate (due to age, sex, genetics), and “perpetuators” that allow the trigger to continue stimulating the substrate.2 90% of electrical “triggers” come from the pulmonary veins “Perpetuators” influence how the autonomic nervous system interacts with the triggers and substrate to perpetuate atrial fibrillation. Sleep apnea, obesity, and other risk factors are the “perpetuators” Over time, as atrial fibrillation recurs, the substrate remodels to result in persistent atrial fibrillation. 3. What are some of the risk factors for atrial fibrillation and what are the possible benefits of controlling them?
Step 1 QBank: step1.mehlmanmedical.comStep 2CK QBank: step2.mehlmanmedical.comStep 3 QBank: step3.mehlmanmedical.comIG: https://www.instagram.com/mehlman_medical/Telegram: https://mehlmanmedical.com/subscribe/
Dr. Brittany Bruggeman joins host Dr. Edith Bracho-Sanchez to talk about diabetes. They go over the differences between Type 1 and Type 2 Diabetes, causes and risk factors, and how diet and exercise can make a difference. They also talk about the importance of destigmatizing weight and how early screenings can help with prevention. For resources go to healthychildren.org/podcast.
Nutritionist Leyla Muedin discusses recent advancements in the detection and prevention of Alzheimer's disease. Topics include the new FDA-approved Lumipulse blood test, the role of a ketogenic diet in improving mitochondrial health, and the significance of lifestyle changes such as social and cognitive activities. The episode also highlights promising research from the University of California Irvine on using natural compounds like nicotinamide and EGCG to rejuvenate aging brain cells and address the buildup of Alzheimer's-associated proteins. Leyla also provides insights into the difference between Alzheimer's and general dementia and emphasizes the importance of accurate diagnosis and appropriate treatments.
Dr. Bruce Baird reveals how shifting responsibility back to patients through education and clear communication frees dentists from unnecessary stress and builds a stronger practice.
Gestational diabetes (GDM) is one of the most common health issues during pregnancy, and diagnosing it is more complicated than you might think. In this episode, Dr. Dekker is joined by EBB Research Team member Dr. Morgan Richardson Cayama to cover the newly updated evidence on how GDM is diagnosed. They walk through the physiology behind GDM, current testing methods, and why there's still international disagreement about how to screen. Together, they examine the results of large randomized trials comparing the one-step and two-step screening methods, the research on early screening with hemoglobin A1C, and the evidence on alternatives to the Glucola drink, including candy and home blood sugar monitoring. They also review the risks of skipping screening entirely, and how weight bias and other systemic factors can impact diagnosis and care. (02:28) What is Gestational Diabetes and Why Is It So Common? (06:30) Risk Factors, Size Bias, and the Role of Race and Ethnicity (10:40) Why We Screen and the Origins of the Controversy (13:17) Comparing the One-Step and Two-Step Methods (19:55) What New Research Says About Health Outcomes (23:45) Should We Screen for GDM Earlier in Pregnancy? (28:11) Can Hemoglobin A1C Replace the Glucola Drink? (32:44) Alternatives: Candy, Food, and Home Monitoring (40:04) What International Guidelines Recommend (43:07) Declining GDM Testing: What the Evidence Shows (47:47) Is Sperm Linked to Gestational Diabetes Risk? (51:29) Takeaways and the Future of GDM Diagnosis Resources Download the free two-page handout in English or Spanish [NEED LINK] Explore Real Food for Gestational Diabetes by Lily Nichols: realfoodforgd.com For a full list of resources, visit ebbirth.com/inducinggdm For more information about Evidence Based Birth® and a crash course on evidence based care, visit www.ebbirth.com. Follow us on Instagram and YouTube! Ready to learn more? Grab an EBB Podcast Listening Guide or read Dr. Dekker's book, "Babies Are Not Pizzas: They're Born, Not Delivered!" If you want to get involved at EBB, join our Professional membership (scholarship options available) and get on the wait list for our EBB Instructor program. Find an EBB Instructor here, and click here to learn more about the EBB Childbirth Class.
We break down pneumothorax: risks, diagnosis, and management pearls. Hosts: Christopher Pham, MD Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Pneumothorax.mp3 Download Leave a Comment Tags: Chest Trauma, Pulmonary, Trauma Show Notes Risk Factors for Pneumothorax Secondary pneumothorax Trauma: rib fractures, blunt chest trauma (as in the case). Iatrogenic: central line placement, thoracentesis, pleural procedures. Primary spontaneous pneumothorax Young, tall, thin males (10–30 years). Connective tissue disorders: Marfan, Ehlers-Danlos. Underlying lung disease: COPD with bullae, interstitial lung disease, CF, TB, malignancy. Technically, anyone is at risk. Symptoms & Differential Diagnosis Typical PTX presentation: Dyspnea, chest pain, pleuritic discomfort. Exam clues: unilateral decreased breath sounds, focal tenderness/crepitus. Red flags (suggest tension PTX): JVD Tracheal deviation Hypotension, shock physiology Severe tachycardia, hypoxia Differential diagnoses: Pulmonary: asthma, COPD, pneumonia, pulmonary edema (SCAPE), ILD, infections. Cardiac: ACS, CHF, pericarditis. PE and other acute causes of dyspnea. Diagnostics Bloodwork: limited role, except type & screen if intervention likely. EKG: reasonable given chest pain/shortness of breath.
As you draft your fantasy football squad this weekend, we want you to relax, have fun, and realize that all the touts who seem so *certain* about everything will be proven wrong in under a week. Draft players you like, the ones you think are good -- you will make mistakes because we all do, but then we'll spend the entire season reviewing tape and fixing them. For today, we'll talk about roster construction early in drafts by rating each player in the ADP top 36 from 1-to-10: how *risky* are they? Plus a heavily revised Joe Mixon profile from the August 29 Almanac Update. Phew! Guest: Jeff Bell from FootballGuys.com. NOTES: Sponsor - www.HungryRoot.com/harris for 40% off your first delivery (and free veggies for life) of healthy groceries and recipes that fit your family's lifestyle Sponsor - www.shopify.com/harris for an e-commerce platform that'll make your small business feel like it's selling like a Fortune 500 company Sponsor - www.fantrax.com/harris for the most customizable, yet simplest fantasy sports platform around Follow Jeff Bell - https://bsky.app/profile/4whomjbelltolls.bsky.social Follow our show on Bluesky - https://bsky.app/profile/harrisfootball.com Follow on Twitter - @HarrisFootball Become a patron - www.patreon.com/harrisfootball Become a Person of the Book - https://www.amazon.com/Christopher-Harris/e/B007V3P4KK Watch the YouTube channel - www.youtube.com/harrisfootball Harris Football Yacht Club Dictionary - https://harrisfootball.github.io/dictionary.html Join the Harris Football Subreddit - www.reddit.com/r/HarrisFootball Subscribe To the Yacht Club Premium Podcast - https://harrisfootball.supportingcast.fm/ Jeff's Risk Factors For The First Three ADP Rounds: 1. Ja'Marr Chase - 1 2. Bijan Robinson - 4 3. Saquon Barkley - 4 4. Jahmyr Gibbs - 3 5. Justin Jefferson - 5 6. CeeDee Lamb - 1 7. Christian McCaffrey - 3 8. Amon-Ra St. Brown - 5 9. Malik Nabers - 4 10. Nico Collins - 2 11. Derrick Henry - 2 12. Ashton Jeanty - 4 13. Puka Nacua - 6 14. Brian Thomas - 5 15. De'Von Achane - 7 16. Drake London - 1 17. Brock Bowers - 2 18. A.J. Brown - 6 19. Jonathan Taylor - 1 20. Bucky Irving - 6 21. Josh Jacobs - 1 22. Chase Brown - 4 23. Lamar Jackson - 6 24. Josh Allen - 6 25. Ladd McConkey - 3 26. Trey McBride - 2 27. Kyren Williams - 4 28. Tee Higgins - 3 29. Tyreek Hill - 10 30. James Cook - 4 31. Jayden Daniels - 7 32. Jaxon Smith-Njigba - 4 33. Omarion Hampton - 4 34. George Kittle - 3 35. Garrett Wilson - 8 36. Mike Evans - 8 Chris's Risk Factors For The First Three ADP Rounds: 1. Ja'Marr Chase - 1 2. Bijan Robinson - 3 3. Saquon Barkley - 2 4. Jahmyr Gibbs - 4 5. Justin Jefferson - 3 6. CeeDee Lamb - 2 7. Christian McCaffrey - 8 8. Amon-Ra St. Brown - 3 9. Malik Nabers - 4 10. Nico Collins - 3 11. Derrick Henry - 3 12. Ashton Jeanty - 7 13. Puka Nacua - 6 14. Brian Thomas - 4 15. De'Von Achane - 8 16. Drake London - 3 17. Brock Bowers - 8 18. A.J. Brown - 4 19. Jonathan Taylor - 4 20. Bucky Irving - 7 21. Josh Jacobs - 2 22. Chase Brown - 4 23. Lamar Jackson - 3 24. Josh Allen - 3 25. Ladd McConkey - 3 26. Trey McBride - 5 27. Kyren Williams - 3 28. Tee Higgins - 5 29. Tyreek Hill - 9 30. James Cook - 4 31. Jayden Daniels - 4 32. Jaxon Smith-Njigba - 3 33. Omarion Hampton - 6 34. George Kittle - 2 35. Garrett Wilson - 7 36. Mike Evans - 6
Tired of Toilets & Trash? Notes vs. Rentals: The Ultimate Investor Showdown!