Podcasts about GI

Midtøsten står i brann, renta har gått ned og Riksrevisjonen slakter det offentlige Norges innsats mot vold og kriminalitet blant unge mennesker. Med Hanne Skartveit, Shazia Majid og Sindre Heyerdahl. Produsent Marcus Møller Pedersen og Fredrik Johansen. Ansvarlig redaktør Gard Steiro. Kontakt redaksjonen på giaeveroggjengen@vg.no. Giæver & gjengen gir deg de viktigste nyhetene hver dag på drøye 20 minutter når du skal hjem fra jobb. Hør «Mediebobler» hver lørdag om feilene pressen gjør og dilemmaer VG står i. Hør «Skartveit» med interessante personer om aktuelle temaer hver søndag. Alltid på Podme.

"I think runners specifically are convinced that sh*tting your pants is normal...I see stuff all the time online of people saying, 'Oh, running causes me to have GI issues.' No, running plus your nutrition is the cause."  Grace Kelley really wants you to be able to run without sh*tting your pants. And she's got the myth-busting reels on Instagram to help! Kelley is a sports dietitian, part of the Lane 9 Directory, and a runner training for her first marathon, Fall 2025. Throughout the process, she's testing out a variety of gels so you don't have to, and keeping a spreadsheet with the facts. She's also making reel after reel of objectively bad nutrition advice from the internet, to save your gut and your run from an ill-informed fueling strategy.  We had a great time chatting with Grace about how she started running on Dry Land (IYKYK) after swimming through high school, how an appointment with a dietitian changed her career path and her own relationship with food, and more about her private practice.  Then we dig into some nutrition trends that may be affecting YOUR gut, and what might help.  Follow her @GraceKelleynutrition on Instagram. And send her bad nutrition things! For the content! Connect with a registered dietitian near you, and find your full team of women's health and sport clinicians, by going to Lane9Project.org/Directory. If you dont' see what you're looking for, fill out our Athlete Match Form, and we'll find someone for you! Follow Lane 9 Project on Instagram @Lane9Project. Subscribe to our weekly newsletter via Lane9Project.Substack.com, and go to Lane9project.org to get in touch if you'd like to send us a note!

In this week's episode, Katie and Elena welcome Alex Larson, RD to the podcast to talk all things fueling and hydration. Alex's mission is to support endurance athletes with practical and simple nutrition advice for lifelong health and performance. She shares valuable insights related to: the biggest mistakes endurance athletes make when it comes to fueling, how to know if you are not fueling enough, how to safely approach changes in body composition (and how to evaluate whether you even should be focusing on body composition changes in the first place), fueling through life stages, meal and snack ideas to support workout timing throughout the day, how and when use supplements, how to properly hydrate, how to calculate your sweat rate, how to manage and avoid GI issues especially in running, and how to effectively carb-load before a big event. This episode is jam-packed full of useful insights that will help you perform in both sport and life. Check it out!View extended show notes for this episode here.To share feedback or ask questions to be featured on a future episode, please use ⁠this form⁠ or email: Katie@TheEnduranceDrive.com.

A listener asks if being eligible for the GI Bill might reduce his merit aid. Ben and Nathan say it's possible schools assume GI benefits mean guaranteed payment, but it shouldn't stop him from getting great offers if he applies broadly with a strong LSAT. Read more on our website. Email daily@lsatdemon.com with questions or comments. Watch this episode on YouTube!

Dr. John Sweetenham and Dr. Erika Hamilton highlight key abstracts that were presented at ASCO25, including advances in breast and pancreatic cancers as well as remarkable data from the use of structured exercise programs in cancer care. Transcript Dr. Sweetenham: Hello, and welcome to the ASCO Daily News Podcast. I'm your host, Dr. John Sweetenham. Today, we'll be discussing some of the key advances and novel approaches in cancer care that were presented at the 2025 ASCO Annual Meeting. I'm delighted to be joined again by the chair of the Meeting's Scientific Program, Dr. Erika Hamilton. She is a medical oncologist and director of breast cancer and gynecologic cancer research at the Sarah Cannon Research Institute in Nashville, Tennessee.  Our full disclosures are available in the transcript of this episode. Dr. Hamilton, congratulations on a fantastic meeting. From the practice-changing science to the world-renowned speakers at this year's Meeting, ASCO25 really reflected the amazing progress we're seeing in oncology today and the enormous opportunities that lie ahead of us. And thanks for coming back on to the podcast today to discuss some of these advances. Dr. Hamilton: Thanks, Dr. Sweetenham. I'm happy to join you today. It really was an impactful ASCO Annual Meeting. I probably am biased, but some great research was presented this year, and I heard lots of great conversations happening while we were there. Dr. Sweetenham: Yeah, absolutely. There was a lot of buzz, as well as a lot of media buzz around the meeting this year, and I think that's probably a good place to start. So I'd like to dive into abstract number LBA3510. This was the CHALLENGE trial, which created a lot of buzz at the meeting and subsequently in the media. This is the study that was led by the NCI Canada Clinical Trials Group, which was the first randomized phase 3 trial in patients with stage III and high-risk stage II colon cancer, which demonstrated that a post-treatment structured exercise program is both feasible and effective in improving disease-free survival in this patient group. The study was performed over a long period of time and in many respects is quite remarkable. So, I wonder if you could give us your thoughts about this study and whether you think that this means that our futures are going to be full of structured exercise programs for those patients who may benefit. Dr. Hamilton: It's a fantastic question. I think that this abstract did create a lot of buzz. We were very excited when we read it. It was highlighted in one of the Clinical Science Symposium sessions. But briefly, this was a phase 3 randomized trial. It was conducted at 55 centers, so really a broad experience, and patients that had resected colon cancer who completed adjuvant therapy were allowed to participate. There were essentially 2 groups: a structured exercise program, called ‘the exercise group,' or health education materials alone, so that was called just ‘the health education group.' And this was a 3-year intervention, so very high quality. The primary end point, as you mentioned, was disease-free survival. This actually accrued from 2009 to 2024, so quite a lift, and almost 900 patients underwent randomization to the exercise group or the health education group. And at almost 8 years of follow-up, we saw that the disease-free survival was significantly longer in the exercise group than the health education group. This was essentially 80.3% of patients were disease-free in exercise and 73.9% in the health education group. So a difference of over 6 percentage points, which, you know, at least in the breast cancer world, we make decisions about whether to do chemotherapy or not based on these kind of data. We also looked at overall survival in the exercise group and health education group, and the 8-year overall survival was 90.3% in the exercise group and 83.2% in the health education group. So this was a difference of 7.1%. Still statistically significant. I think this was really a fantastic effort over more than a decade at over 50 institutions with almost 900 patients, really done in a very systematic, high-intervention way that showed a fantastic result. Absolutely generalizable for patients with colon cancer. We have hints in other cancers that this is beneficial, and frankly, for our patients for other comorbidities, such as cardiovascular, etc., I really think that this is an abstract that deserved the press that it received. Dr. Sweetenham: Yeah, absolutely, and it is going to be very interesting, I think, over the next 2 or 3 years to see how much impact this particular study might have on programs across the country and across the world actually, in terms of what they do in this kind of adjuvant setting for structured exercise. Dr. Hamilton: Absolutely.  So let's move on to Abstract 3006. This was an NCI-led effort comparing genomic testing using ctDNA and tissue from patients with less common cancers who were enrolled in but not eligible for a treatment arm of the NCI-MATCH trial. Tell us about your takeaways from this study. Dr. Sweetenham: Yeah, so I thought this was a really interesting study based, as you said, on NCI-MATCH. And many of the listeners will probably remember that the original NCI-MATCH study screened almost 6,000 patients to assess eligibility for those who had an actionable mutation. And it turned out that about 60% of the patients who went on to the study had less common tumors, which were defined as anything other than colon, rectum, breast, non–small cell lung cancer, or prostate cancer. And most of those patients lacked an eligible mutation of interest and so didn't get onto a trial therapy. But with a great deal of foresight, the study group had actually collected plasma samples from these patients so that they would have the opportunity to look at circulating tumor DNA profiles with the potential being that this might be another way for testing for clinically relevant mutations in some of these less common cancer types. So initially, they tested more than 2,000 patients, and to make a somewhat complicated story short, there was a subset of five histologies with a larger representation in terms of sample size. And these were cholangiocarcinoma, small cell lung cancer, esophageal cancer, pancreatic, and salivary gland cancer. And in those particular tumors, when they compared the ctDNA sequencing with the original tumor, there was a concordance there of around 84%, 85%. And in the presentation, the investigators go on to list the specific mutated genes that were identified in each of those tumors. But I think that the other compelling part of this study from my perspective was not just that concordance, which suggests that there's an opportunity there for the use of ctDNA instead of tumor biopsies in some of these situations, but what was also interesting was the fact that there were several clinically relevant mutations which were detected only in the circulating tumor DNA. And a couple of examples of those included IDH1 for cholangiocarcinoma, BRAF and p53 in several histologies, and microsatellite instability was most prevalent in small cell lung cancer in the ctDNA. So I think that what this demonstrates is that liquid biopsy is certainly a viable screening option for patients who are being assessed for matching for targeted therapies in clinical trials. The fact that some of these mutations were only seen in the ctDNA and not in the primary tumor specimen certainly suggests that there's some tumor heterogeneity. But I think that for me, the most compelling part of this study was the fact that many of these mutations were only picked up in the plasma. And so, as the authors concluded, they believe that a comprehensive gene profiling with circulating tumor DNA probably should be included as a primary screening modality in future trials of targeted therapy of this type. Dr. Hamilton: Yeah, I think that that's really interesting and mirrors a lot of data that we've been seeing. At least in breast cancer, you know, we still do a biopsy up front to make sure that our markers, we're still treating the right disease that we think we are. But it really speaks to the utility of using ctDNA for serial monitoring and the emergence of mutations. Dr. Sweetenham: Absolutely. And you mentioned breast cancer, and so I'd like to dwell on that for a moment here because obviously, there was a huge amount of exciting breast cancer data presented at the meeting this year. And in particular, I'd like to ask you about LBA1008, the DESTINY-Breast09 clinical trial, which I think has the potential to establish a new first-line standard of care for metastatic HER2+ breast cancer. And that's an area where we haven't seen a whole lot of innovation for around a decade now. So can you give us some of the highlights of this trial and what your thinking is, having seen the results? Dr. Hamilton: Yeah, absolutely. So this was a trial in the first-line metastatic HER2 setting. So this was looking at trastuzumab deruxtecan. We certainly have had no shortage of reports around this drug, initially approved for later lines. DESTINY-Breast03 brought it into our second-line setting for HER2+ disease and we're now looking at DESTINY-Breast09 in first-line. So this actually was a 3-arm trial where patients were randomized 1:1:1 against standard taxane/trastuzumab/pertuzumab in one arm; trastuzumab deruxtecan with pertuzumab in another arm; and then a third arm, trastuzumab deruxtecan alone. And what we did not see reported was that trastuzumab deruxtecan-alone arm. But we did have reports from the trastuzumab deruxtecan plus pertuzumab versus the chemo/trastuzumab/pertuzumab. And what we saw was a statistically significant improvement in median progression-free survival, 26.9 months up to 40.7, so an improvement of 13.8 months, over a year in PFS. Not to mention that we're now in the 40-month range for PFS in first-line disease. Really, across all subgroups, we really weren't able to pick out a subset of patients that did not benefit. We did see about a 12% ILD rate with trastuzumab deruxtecan. That really is on par with what we've seen in other studies, around 10%-15%. I think that this is going to become a new standard of care in the first-line. I think it did leave some unanswered questions. We saw some data from the PATINA trial this past San Antonio Breast, looking at the addition of endocrine therapy with or without a CDK4/6 inhibitor, palbociclib, for those patients that also have ER+ disease, after taxane has dropped out in the first-line setting. So how we're going to kind of merge all this together is, I suspect that there are going to be patients that we or they just don't have the appetite to continue 3 to 4 years of trastuzumab deruxtecan. And so we're probably going to be looking at a maintenance-type strategy for them, maybe integrating the PATINA data there. But how we really put this into practice in the first-line setting and if or when we think about de-escalating down from trastuzumab deruxtecan to antibody therapy are some lingering questions. Dr. Sweetenham: Okay, so certainly is going to influence practice, but watch this space for a little bit longer, it sounds as though that's what you're saying. Dr. Hamilton: Absolutely.  So let's move on to GI cancer. Abstract 4006 reported preliminary results from the randomized phase 2 study of elraglusib in combination with gemcitabine/nab-paclitaxel versus the chemo gemcitabine/nab-paclitaxel alone in patients with previously untreated metastatic pancreatic cancer. Can you tell us more about this study? Dr. Sweetenham: Yeah, absolutely. As you mentioned, elraglusib is actually a first-in-class inhibitor of GSK3-beta, which has multiple potential actions in pancreatic cancer. But the drug itself may be involved in mediating drug resistance as well as in some tumor immune response modulation. Some of that's not clearly understood, I believe, right now. But certainly, preclinical data suggests that the drug may be effective in preclinical models and may also be effective in combination with chemotherapy and potentially with immune-modulating agents as well. So this particular study, as you said, was an open-label, randomized phase 2 study in which patients with pancreatic cancer were randomized 2:1 in favor of the elraglusib plus GMP—gemcitabine and nab-paclitaxel—versus the chemotherapy alone. And upon completion of the study, which is not right now, median overall survival was the primary end point, but there are a number of other end points which I'll talk about in just a moment. But the sample size was planned to be around 207 patients. The primary analysis included 155 patients in the combination arm versus 78 patients in the gemcitabine/nab-paclitaxel arm. Overall, the 1-year overall survival rate was 44.1% for the patients in the elraglusib-containing arm versus 23.0% in the patients receiving gemcitabine/nab-paclitaxel only. When they look at the median overall survival, it was 9.3 months for the experimental arm versus 7.2 months for chemotherapy alone. So put another way, there's around a 37% reduction in the risk of death with the use of this combination arm. The treatment was overall well-tolerated. There were some issues with grade 1 to 2 transient visual impairment in a large proportion of the patients. The most common treatment-related adverse effects with the elraglusib/GMP combination was transient visual impairment, which affected around 60% of the patients. Most of the more serious treatment-related adverse events included neutropenia, anemia, and fatigue in 50%, 25%, and 16% of the patients, respectively. So the early results from this study show a significant benefit for 1-year overall survival and for median overall survival with, as I mentioned above, a significant reduction in the risk of death. The authors went on to mention that the median overall survival for the control arm in this study is somewhat lower than in other comparable trials, but they think that this may be related to a more advanced disease burden in this particular study. Of interest to me was that right now: there is no apparent difference in progression-free survival between the 2 arms of this study. The authors described this as potentially indicating that this may be related in some way to immune modulation and immune effects on the tumor, which, if I'm completely honest, I don't totally understand. And so, the improvement in overall survival, as far as I can see at the moment, is not matched by an improvement in progression-free survival. So I think we probably need to wait for more time to elapse to see what happens with the study. And so, I think it certainly is an interesting study, and the results are intriguing, but I think it's probably a little early for it to actually shift the treatment paradigm in this disease. Dr. Hamilton: Fantastic. I think we've been waiting for advances in pancreatic cancer for a long time, but this, not unlike others, we learn more and then learn more we don't realize, so. Dr. Sweetenham: Right. Let's shift gears at this point and talk about a couple of other abstracts in kind of a very different space. Let's start out with symptom management for older adults with cancer. We know that undertreated symptoms are common among the older patient population, and Abstract 11002 reported on a randomized trial that demonstrated the effects of remote monitoring for older patients with cancer in terms of kind of symptoms and so on. Can you tell us a little bit about this study and whether you think this approach will potentially improve care for older patients? Dr. Hamilton: Yeah, I really liked this abstract. It was conducted through the Veterans Affairs, and it was based in California, which I'm telling you that because it's going to have a little bit of an implication later on. But essentially, adults that were 75 years or older who were Medicare Advantage beneficiaries were eligible to participate. Forty-three clinics in Southern California and Arizona, and patients were randomized either into a control group of usual clinic care alone, or an intervention group, which was usual care plus a lay health worker-led proactive telephone-based weekly symptom assessment, and this was for 12 months using the validated Edmonton Symptom Assessment System. So, there was a planned enrollment of at least 200 patients in each group. They successfully met that. And this lay health worker reviewed assessments with a physician assistant, who conducted follow-up for symptoms that changed by 2 points from a prior assessment or were rated 4 or greater. So almost a triage system to figure out who needed to be reached out to and to kind of work on symptoms. What I thought was fantastic about this was it was very representative of where it enrolled. There were actually about 50% of patients enrolled here that were Hispanic or Latinos. So some of our underserved populations and really across a wide variety of tumor types. They found that the intervention group had 53% lower odds of emergency room use, 68% lower odds of hospital use than the control group. And when they translated this to actual total cost of care, this was a savings of about $12,000 U.S. per participant and 75% lower odds of a death in an acute care facility. So I thought this was really interesting for a variety of reasons. One, certainly health care utilization and cost, but even more so, I think any of our patients would want to prevent hospitalizations and ER visits. Normally, that's not a fantastic experience having to feel poorly enough that you're in the emergency room or the hospital. And really showing in kind of concrete metrics that we were able to decrease this with this intervention. In terms of sustainability and scalability, I think the question is really the workforce to do this. Obviously, you know, this is going to take dedicated employees to have the ability to reach out to these patients, etc., but I think in value-based care, there's definitely a possibility of having reimbursement and having the funds to institute a program like this. So, definitely thought-provoking, and I hope it leads to more interventions. Dr. Sweetenham: Yeah, we've seen, over several years now, many of these studies which have looked at remote symptom monitoring and so on in this patient population, and many of them do show benefits for that in kinds of end points, not the least in this study being hospitalization and emergency room avoidance. But I think the scalability and personnel issue is a huge one, and I do wonder at some level whether we may see some AI-based platforms coming along that could actually help with this and provide interactions with these patients outside of actual real people, or at least in combination with real people. Dr. Hamilton: Yeah, that's a fantastic point.  So let's talk a little bit about clinical trials. So eligibility assessment for oncology clinical trials, or prescreening, really relies on manual review of unstructured clinical notes. It's time-consuming, it's prone to errors, and Abstract 1508 reported on the final analysis of a randomized trial that looked at the effect of human-AI teams prescreening for clinical trial eligibility versus human-only or AI-only prescreening. So give us more good news about AI. What did the study find? Dr. Sweetenham: Yeah, this is a really, a really interesting study. And of course, any of us who have ever been involved in clinical trials will know that accrual is always a problem. And I think most centers have attempted, and some quite successfully managed to develop prescreening programs so that patients are screened by a health care provider or health care worker prior to being seen in the clinic, and the clinical investigator will then already know whether they're going to be eligible for a trial or not. But as you've already said, it's a slow process. It's typically somewhat inefficient and requires a lot of time on the part of the health care workers to actually do this in a successful way. And so, this was a study from Emory University where they took three models of ways in which they could assess the accuracy of the prescreening of charts for patients who are going to be considered for clinical trials. One of these was essentially the regular way of having two research coordinators physically abstract the charts. The second one was an AI platform which would extract longitudinal EHR data. And then the third one was a combination of the two. So the AI would be augmented by the research coordinator or the other way around. As a gold standard, they had three independent oncology reviewers who went through all of these charts to provide what they regarded as being the benchmark for accuracy. In a way, it's not a surprise to me because I think that a number of other systems which have used this combination of human verification of AI-based tools, it actually ultimately concluded that the combination of the two in terms of chart accuracy was for the most part better than either one individually, either the research coordinator or the AI alone. So I'll give you just a few examples of where specifically that mattered. The human plus AI platform was more accurate in terms of tumor staging, in terms of identifying biomarker testing and biomarker results, as well as biomarker interpretation, and was also superior in terms of listing medications. There are one or two other areas where either the AI alone was somewhat more accurate, but the significant differences were very much in favor of a combination of human + AI screening of these patient charts. So, in full disclosure, this didn't save time, but what the authors reported was that there were definite efficiency gains, and presumably this would actually become even more improved once the research coordinators were somewhat more comfortable and at home with the AI tool. So, I thought it was an interesting way of trying to enhance clinical trial accrual up front by this combination of humans and technology, and I think it's going to be interesting to see if this gets adopted at other centers in the future. Dr. Hamilton: Yeah, I think it's really fascinating, all the different places that we can be using AI, and I love the takeaway that AI and humans together are better than either individually. Dr. Sweetenham: Absolutely.  Thanks once again, Dr. Hamilton, for sharing your insights with us today and for all of the incredible work you did to build a robust program. And also, congratulations on what was, I think, a really remarkable ASCO this year, one of the most exciting for some time, I think. So thank you again for that. Dr. Hamilton: Thanks so much. It was really a pleasure to work on ASCO 2025 this year. Dr. Sweetenham: And thank you to our listeners for joining us today. You'll find links to all the abstracts we discussed today in the transcript of this episode. Be sure to catch up on all of our coverage from the Annual Meeting. You can catch up on my daily reports that were published each day of the Annual Meeting, featuring the key science and innovations presented. And we'll have wrap-up episodes publishing in June, covering the full spectrum of malignancies from ASCO25. If you value the insights you hear on the ASCO Daily News Podcast, please remember to rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.   More on today's speakers: Dr. John Sweetenham   Dr. Erika Hamilton @erikahamilton9   Follow ASCO on social media:  @ASCO on Twitter  ASCO on Bluesky  ASCO on Facebook   ASCO on LinkedIn     Disclosures:     Dr. John Sweetenham:     No relationships to disclose    Dr. Erika Hamilton: Consulting or Advisory Role (Inst): Pfizer, Genentech/Roche, Lilly, Daiichi Sankyo, Mersana, AstraZeneca, Novartis, Ellipses Pharma, Olema Pharmaceuticals, Stemline Therapeutics, Tubulis, Verascity Science, Theratechnologies, Accutar Biotechnology, Entos, Fosun Pharma, Gilead Sciences, Jazz Pharmaceuticals, Medical Pharma Services, Hosun Pharma, Zentalis Pharmaceuticals, Jefferies, Tempus Labs, Arvinas, Circle Pharma, Janssen, Johnson and Johnson   Research Funding (Inst): AstraZeneca, Hutchison MediPharma, OncoMed, MedImmune, Stem CentRx, Genentech/Roche, Curis, Verastem, Zymeworks, Syndax, Lycera, Rgenix, Novartis, Millenium, TapImmune, Inc., Lilly, Pfizer, Lilly, Pfizer, Tesaro, Boehringer Ingelheim, H3 Biomedicine, Radius Health, Acerta Pharma, Macrogenics, Abbvie, Immunomedics, Fujifilm, eFFECTOR Therapeutics, Merus, Nucana, Regeneron, Leap Therapeutics, Taiho Pharmaceuticals, EMD Serono, Daiichi Sankyo, ArQule, Syros Pharmaceuticals, Clovis Oncology, CytomX Therapeutics, InventisBio, Deciphera, Sermonix Pharmaceuticals, Zenith Epigentics, Arvinas, Harpoon, Black Diamond, Orinove, Molecular Templates, Seattle Genetics, Compugen, GI Therapeutics, Karyopharm Therapeutics, Dana-Farber Cancer Hospital, Shattuck Labs, PharmaMar, Olema Pharmaceuticals, Immunogen, Plexxikon, Amgen, Akesobio Australia, ADC Therapeutics, AtlasMedx, Aravive, Ellipses Pharma, Incyte, MabSpace Biosciences, ORIC Pharmaceuticals, Pieris Pharmaceuticals, Pieris Pharmaceuticals, Pionyr, Repetoire Immune Medicines, Treadwell Therapeutics, Accutar Biotech, Artios, Bliss Biopharmaceutical, Cascadian Therapeutics, Dantari, Duality Biologics, Elucida Oncology, Infinity Pharmaceuticals, Relay Therapeutics, Tolmar, Torque, BeiGene, Context Therapeutics, K-Group Beta, Kind Pharmaceuticals, Loxo Oncology, Oncothyreon, Orum Therapeutics, Prelude Therapeutics, Profound Bio, Cullinan Oncology, Bristol-Myers Squib, Eisai, Fochon Pharmaceuticals, Gilead Sciences, Inspirna, Myriad Genetics, Silverback Therapeutics, Stemline Therapeutics

VOV1 - Dịp kỷ niệm 50 năm Giải phóng miền Nam, thống nhất đất nước là dấu mốc lịch sử và trải nghiệm khó quên với những nhà báo tham gia tác nghiệp. Hòa mình vào dòng chảy sự kiện, họ đã ghi lại khoảnh khắc, cảm nhận sâu sắc nhịp đập tự hào của dân tộc.

What if your bloating, bowels, or other stomach symptoms were more than just a nuisance—and were actually holding you back from getting pregnant or having regular cycles? On this episode of Cycle Wisdom, Dr. Monica Minjeur explores how gut health can silently sabotage fertility and reproductive hormones. From the gut-immune-hormone axis to the estrobolome, we break down what the science actually says about GI symptoms, inflammation, and their link to conditions like endometriosis, PCOS, and even miscarriage risk.You'll hear Wendy's story—a night-shift nurse whose infertility journey turned around after treating gut inflammation—and walk away with practical, hopeful strategies to improve your gut and your cycle. We'll also explain the role of testing, including looking for bacterial overgrowth and food sensitivities, and how Restorative Reproductive Medicine can help women restore hormonal health from the inside out.

Send us a textIn this episode, Alyssa Simpson a Gut Health Dietitian and Food-first digestive health coach, dives into how to make greens your gut's best friend. Instead of focusing on what to eliminate from your diet, Alyssa emphasizes how to include greens in ways that support gut health without discomfort. Whether you're navigating IBS, SIBO, or histamine intolerance, this episode is packed with practical tips to help you embrace the power of greens.Resources Mentioned:Download Alyssa's Low FODMAP Green Goddess Salad Recipe.Try her Veggie Mash GuideDM “GUT CHECK” on Alyssa's Instagram for a personalized quiz and free meal plans & resources to kickstart your gut healing journey.Check out Alyssa's FREE Masterclass “Why your gut still isn't better - the real reason you feel stuck here. Find Alyssa on: Instagram, LinkedIn, Facebook, Pinterest  -If you're enduring uncomfortable, painful, and embarrassing GI symptoms and feel like you've tried everything, Alyssa uses a specialized approach to help people who've gone from doctor to doctor finally find relief. Book your 15-minute strategy call for FREE here.Tune in and subscribe to "The Gut Health Dialogues" for inspiring client transformation stories and expert insights into gut health. Leave a review—Your support will help Alyssa empower more people with the knowledge and tools to take control of their gut health and reclaim their lives. Looking for a supportive Gut Health community? Alyssa is building a community committed to helping people overcome their digestive symptoms by addressing the root cause using food and nutrition. Join Alyssa's FREE Facebook Community here.

In celebration of Father's day, Gi's been digging through the archives again! She's put together some of her favourite chats from some of her favourite dads, including:Tom Fletcher on how miscarriage affects dads tooJeff Brazier on trying to give his kids what he didn't have growing upPaul C Brunson on men's emotional healthMatt Willis on how fatherhood was a turning point in fighting addictionJames Buckley on having an open dialogue with his teensPlus, keep listening to hear a VIP guest - Max Fletcher talks about what makes a great dad! Hosted on Acast. See acast.com/privacy for more information.

Picture this: A new parent is changing the diaper of their one-month-old infant when they notice streaks of blood. That's when panic sets in, followed by frantic calls to the pediatrician's office. But is this always a cause for alarm? In this episode, our gastroenterologists are on the case. We're talking about allergic proctitis in infants. They will help you recognize and manage this common newborn issue so you can support families. Joining us for this episode is Mason Nistel, MD. He specializes in gastroenterology at Children's Hospital Colorado and is an Assistant Professor of pediatric GI, hepatology and nutrition at the University of Colorado School of Medicine.   Some highlights from this episode include:  How a typical case of allergic proctitis presents  Key differences between problematic blood and ‘normal' blood in the stool  The importance of tapping into empathy as this can be a scary experience for parents  Additional considerations for primary care providers when evaluating blood in stool   For more information on Children's Colorado, visit: childrenscolorado.org. 

Discover why the GUT Zoomer 3.0 is revolutionizing functional medicine GI testing! Dr. Eric Balcavage interviews Adair Anderson, RD from Vibrant Labs, for an in-depth analysis of this comprehensive stool test that goes far beyond basic bacterial balance. Key Topics Covered: ✅ GUT Zoomer vs Traditional Testing: Why gastroenterologist tests miss root causes ✅ Advanced Testing Technology: RT-PCR, biofilm disruption, and LC-MS/MS methodology ✅ Complete Gut Assessment: Commensals, pathogens, metabolites, and digestive markers ✅ Short-Chain Fatty Acids: Critical role in gut barrier function and immune regulation ✅ Zonulin & Intestinal Permeability: Understanding leaky gut and systemic inflammation ✅ Secretory IgA Interpretation: Why total IgA levels don't tell the whole story ✅ Testing Protocol: Why to test without supplements for accurate baseline results ✅ Molecular Mimicry: Cross-reactivity concerns with gluten and other proteins Perfect for: Thyroid patients with persistent digestive issues Practitioners seeking comprehensive functional GI testing Anyone struggling with chronic GI problems despite normal colonoscopy results Patients wanting to understand root causes before disease develops Expert Insights on:  When standard GI tests fail to identify problems - How stress impacts pancreatic enzyme production Why biofilm disruption matters for accurate results Post-colonoscopy testing recommendations (wait 2 weeks!) Learn why the GUT Zoomer 3.0's evidence-based methodology and comprehensive analysis make it superior to direct-to-consumer tests and traditional stool testing. Timestamps: [00:00] Introduction & Adair's Background [05:30] Standard vs Functional GI Testing [12:15] GUT Zoomer Advantages & Technology [18:45] Direct-to-Consumer Test Limitations [24:20] Biofilm Disruption Critical Process [31:10] Commensals vs Pathogens Deep Dive [38:25] Factors Affecting Gut Health [45:50] Interpreting GUT Zoomer Results [52:30] Short-Chain Fatty Acids (SCFAs) Role [58:15] Intestinal Permeability & Zonulin [64:40] Cross-Contamination & Gluten Exposure [69:20] Molecular Mimicry & Test Specificity [74:35] Secretory IgA Interpretation [80:10] Testing Protocol Best Practices [85:45] Final Tips for Chronic GI Issues Adair Anderson is a Registered and Licensed Dietitian Nutritionist. She holds a Master's degree in Clinical Nutrition from Bastyr University and has a strong background in biochemistry, having earned a Bachelor's degree in Biochemistry from Earlham College. Adair has extensive experience in the field and has served on the boards of various nutrition and dietetics organizations. She specializes in helping clients overcome gastrointestinal conditions and focuses on resolving root-cause digestive issues using evidence-based, functional testing. Adair lives in Washington, DC with her husband, five bikes, and a growing succulent collection. When not working, she enjoys cycling, rock climbing, weightlifting, and yoga. #GutHealth #FunctionalMedicine #ThyroidGutConnection #GITesting #LeakyGut #Microbiome #ThyroidRecovery"

Send us a textIn this episode of the IBS Nutrition Podcast, I'm joined by Dr. Ali Navidi — a licensed clinical psychologist and co-founder of GI Psychology — to explore how the gut-brain connection drives IBS symptoms, and how targeted psychological treatment can lead to lasting relief.We dive into what the gut-brain axis really is (without the medical jargon), when to seek support from a GI psychologist, and how tools like gut-directed CBT and clinical hypnosis can break the vicious cycle of symptom-anxiety-symptom. Whether you've been told “it's all in your head” or you're feeling stuck after trying diet changes alone, this episode will show you that IBS relief is possible with the right care team.In This Episode, You'll Learn:✔ What the gut-brain axis is and how it fuels IBS symptoms✔ Why IBS isn't “just in your head” (and how to break the shame cycle)✔ When to seek support from a GI psychologist — and why sooner is better✔ How treatment works: CBT, hypnotherapy, and tailored assessment✔ The role of food fear, avoidance, and nervous system dysregulation✔ Dr. Navidi's top 3 actionable tips to calm your gut and mind right nowTimestamps:[00:00] Welcome & intro to Dr. Ali Navidi[01:32] What is the gut-brain connection?[04:18] Why IBS isn't "just in your head"[07:37] Hypervigilance and the anxiety feedback loop[09:39] When to seek GI psych support[13:01] How assessments & treatment work[15:39] Gut-directed CBT vs. clinical hypnosis[17:53] Avoidance behaviours in IBS[20:55] Key takeaways for managing IBS[21:07] Dr. Navidi's 3 actionable steps for symptom relief[26:05] Final message to IBS sufferers[27:36] How to access more supportResources Mentioned:

#Bàigiảng của #ĐứcTGMGiuseNguyễnNăng trong thánh lễ mừng kính Thánh Tâm Chúa Giêsu - Bổn mạng Gia đình Phạt Tạ Thánh Tâm Chúa Giêsu #TGPSG

VOV1 - Sáng nay (17/6), tại Hà Nội, Học viện Chính trị quốc gia HCM tổ chức Đại hội thi đua yêu nước lần thứ VI (2025-2030). Giáo sư- Tiến sĩ Nguyễn Xuân Thắng, Ủy viên Bộ Chính trị, Giám đốc Học viện chính trị quốc gia HCM, Chủ tịch Hội đồng Lý luận Trung ương dự và phát biểu chỉ đạo Đại hội.

VOV1 - Tại diễn đàn “Thực thi ESG trong bất động sản tại Việt Nam – Cơ hội và Giải pháp tài chính bền vững”, các chuyên gia cho rằng, ESG đang ngày càng nhận được sự quan tâm của Chính phủ, các doanh nghiệp và nhà đầu tư và là xu hướng không thể đảo ngược.

As a huge fan of the original Squid Game, cinematographer Kim Ji-yong jumped at the opportunity to shape the visual language for the show's second and third seasons. Ji-yong has masterfully evolved the show's aesthetic, continuing to play with jarring camera perspectives. He uses disorienting low angles looking up and god-like high angles looking down to immerse the viewer in the drama. For him, color and light are the key to unlocking the show's central theme: the tension between childlike innocence and deadly menace. Squid Game Season 2 follows the first season's winner, Seong Gi-hun, as he seeks revenge and tries to uncover the mystery behind the games. In the first episode, Gi-hun and his friends chase a recruiter through a subway and a park, a pursuit that ends in a tense game of Russian roulette. For this pivotal scene, Ji-yong wanted a look that was both realistic and expressionistic. He bathed the game in the glow of a red neon light from a nearby window, establishing a color motif that would echo throughout the season. This powerful visual cue returns in other key episodes, most notably in a harrowing new voting scene where the players must once again decide their own fate. “When our main actor is facing a moment of choice, a moment of making a decision, I wanted to bring that red and blue light every time they faced that situation, just like earlier in the Russian roulette game,” Ji-yong explains. The sheer scale of the sets presented unique lighting challenges, particularly the massive, white-walled dorm room filled with hundreds of extras. "I tried to cut off the spill to the white walls as much as I could," Ji-yong says. "We also had stacks of beds so I could use some shadowy areas, so we had a little variety on the set." All the room's illumination came from a lighting grid above, making it feel as oppressive and controlled as the games themselves, which also served the actors. "I want them to feel as if they're actually playing this game," he notes. To capture the chaos, Ji-yong relied on an intimate two-camera setup. One camera stayed close, capturing the raw emotion on the characters' faces, while the other—often handheld—followed the action from the perspective of a frantic player. Though each episode was meticulously storyboarded and shot over 12 to 15 days, he finalized camera positions after blocking each scene, trusting his intuition to find the most impactful angles. Ji-yong embraced the vibrant, candy-colored sets, finding creative energy in the contrast between their playful hues and the brutal violence of the games. He worked closely with the production designer, running camera tests to find the perfect shade of pink that would pop on screen. While not typically a fan of modern LED RGB lights, he found them essential for this project. The results are unforgettable, especially in the strobing, kaleidoscopic lighting of the "Mingle Game" featuring a carousel. "I have never used this much color in my career,” he laughs. The Cinematography Podcast website: www.camnoir.com YouTube: @TheCinematographyPodcast Facebook: @cinepod Instagram: @thecinepod Blue Sky: @thecinepod.bsky.social

Cậu biết không, rằng tình yêu vốn không thể sụp đổ ngay lập tức chỉ vì một câu nói, mà tình yêu sụp đổ vì rất nhiều câu nói trước đó, cộng với câu nói cuối cùng, ở giây phút cuối cùng.Giá như ngày ấy mình đủ bình tĩnh để nói một lời khác, đủ thấu đáo để hành động khác, hoặc đủ dũng khí để rẽ sang một lối đi khác… thì liệu mọi thứ có còn dừng lại ở hai chữ "kết thúc"? Giá như mình mạnh mẽ hơn một chút để giữ lấy người, và người cũng đủ kiên định để ở lại… thì có lẽ giờ đây chúng mình đã không chỉ là ký ức trong nhau. Nhưng tiếc thay, cuộc đời không vận hành bằng những điều “giá như”. Nó chỉ để lại những tiếng thở dài, những đêm thao thức và những trái tim vẫn chưa thôi tìm cách để níu giữ.Trong tập phát sóng tới đây, Visaothenhi!Radio đã nhận được nhiều dòng tâm sự đến từ những người từng yêu rất sâu, từng đau rất nhiều và mang cho mình những “giá như”. Họ viết cho những người từng là tất cả, gửi đến những mảnh ký ức chưa trọn vẹn một lời kết. Cùng chúng mình ngồi xuống một chút, lắng nghe những mẩu chuyện ấy, và xem thử đằng sau mỗi chữ "giá như" ấy, rốt cuộc là điều gì còn day dứt trong tim nhé.

Năm Thanh Lọc – Ai sống sót, ai lặng lẽ rời đi?Tui vừa thu xong một tập mà… ngồi thu xong vẫn thấy nghèn nghẹn trong lòng.96.500 doanh nghiệp đóng cửa chỉ trong quý I/2025. Không ồn ào, không drama, chỉ là từng cửa hàng lặng lẽ tắt đèn, từng giấc mơ biến mất không một tiếng động. Li do không phải vì cú sốc lớn, mà vì những vết cắt nhỏ: hóa đơn không trả nổi, đơn hàng bị hủy, mở cửa không ai tới. Họ đã chiến đấu, đã chờ đợi, mòn mỏi đến khi kiệt sức.Còn những ai sống sót? Thì cũng thoi thóp. Một triệu lao động trẻ thất nghiệp, con số cao nhất 5 năm. Nỗi sợ bị bỏ lại, bị đào thải len vào từng cuộc trò chuyện, và cả trong những đêm mất ngủ. Ngay cả tui, làm chủ 20 năm, cũng có lúc thầm lo: “Không biết mình còn trụ nổi bao lâu?”Tui gọi giai đoạn này là Năm Thanh Lọc – một chu kỳ nghiệt ngã nhưng cần thiết. Không chỉ là khủng hoảng, đây là quá trình thị trường làm mới. Những ai yếu kém, ăn xổi, sống nhờ may mắn… thì khó mà sống sót. Nhưng ai đủ bản lĩnh, đủ dũng khí nhìn lại và đổi mới sẽ lột xác. Kinh tế học gọi là “Phá huỷ sáng tạo”. Tâm linh gọi là năm Tỵ – năm con rắn lột da để tái sinh.Điều thứ hai: khách hàng không biến mất, nhưng họ thay đổi. Giờ họ kỹ tính, lý trí và thực tế hơn. Họ mua ít hơn, nhưng chọn kỹ hơn. Và nghịch lý là, khi kinh tế khó khăn, họ lại sẵn sàng chi cho những liều thuốc tinh thần nhỏ bé: món ăn vặt, game thư giãn, dịch vụ giải toả stress. Nếu bạn làm kinh doanh, hãy nhìn sâu hơn: khách hàng vẫn cần bạn – chỉ là họ cần một bạn khác đi.Điều cuối cùng, và có lẽ quan trọng nhất: chủ doanh nghiệp phải giữ vững tinh thấn. Đội ngũ cần bạn như cần ngọn hải đăng giữa bão. Chúng ta đã và sẽ trải qua những đợt sóng như thế và từ đó rất nhiều doanh nghiệp đã lột xác thành công, rất nhiều sản phẩm mới mẻ sáng tạo giải quyết những nhu cầu tân tiếng nhất ra đời… Họ không phải may mắn. Họ đơn giản là không bỏ cuộc, và đổi mới liên tục.Nếu bạn đang thấy bất an, mất phương hướng, tập này không phải để “trấn an”, mà để giúp bạn tỉnh táo hơn, quyết liệt hơn. Vì sau cơn mưa, chỉ những người kiên cường mới thấy được cầu vồng.Mời bạn nghe tập mới và chia sẻ góc nhìn cùng Tùng BT nhé!

Kåre Aas er en av Norges fremste diplomater, nå pensjonert. Han kjenner Midtøsten bedre enn de fleste, derfor er han et naturlig valg når Israel angriper Iran og et Midtøsten i brann kan ta full fyr. Lydmastring av Andreas Røen Pettersen. Ansvarlig redaktør Gard Steiro. Kontakt redaksjonen på giaeveroggjengen@vg.no. Giæver & gjengen gir deg de viktigste nyhetene hver dag på drøye 20 minutter når du skal hjem fra jobb. Hør «Mediebobler» hver lørdag om feilene pressen gjør og dilemmaer VG står i. Hør «Skartveit» med interessante personer om aktuelle temaer hver søndag. Alltid på Podme. (Episoden ble tatt opp fredag ettermiddag, før Iran svarte på Israels angrep)

Welcome to another episode of the Oncology Brothers podcast! In this episode, Drs. Rahul and Rohit Gosain are joined by Dr. Cathy Eng, a renowned GI medical oncologist from the Vanderbilt Ingram Cancer Center, to discuss the most impactful updates from the ASCO 2025 annual meeting, specifically focusing on gastrointestinal (GI) malignancies. Join us as we dive into five pivotal abstracts that are set to change the landscape of GI cancer treatment: 1.⁠ ⁠DYNAMIC III: Discover how ctDNA-guided adjuvant chemotherapy in stage 3 colon cancer did not improve outcomes, highlighting questionable role of escalating approach with ctDNA positivity. 2.⁠ ⁠ATOMIC: Learn about the addition of atezolizumab to FOLFIRI in MSI-H disease stage 3 colon cancer, which improved disease-free survival with a hazard ratio of 0.50. 3.⁠ ⁠BREAKWATER: Explore how the combination of encorafenib, cetuximab, and FOLFOX has established a new standard of care for BRAF V600E mutant metastatic colorectal cancer, doubling overall survival from 15 months to 30.3 months. 4.⁠ ⁠MATTERHORN: Understand the use of durvalumab in the perioperative and postoperative setting with the FLOT regimen for resectable gastric and GE junction adenocarcinoma, showing significant improvements in event-free survival. 5.⁠ ⁠DESTINY Gastric04: Delved into the findings that confirm TDXd as a preferred option in the second line and beyond for HER2 positive metastatic gastric cancer or GE junction adenocarcinoma. YouTube: https://youtu.be/hllyI5S2Dqg Follow us on social media: •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ Tune in for an insightful discussion that will keep you updated on the latest advancements in GI oncology! Don't forget to subscribe for more episodes on treatment algorithms, FDA approvals, and conference highlights.

Tựa Đề: Ngày Lễ Cha, Nghĩ Về... Một Người Cha Tuyệt Vời Tên Gióp; Tác Giả: Mục Sư Nguyễn Đình Liễu; Loạt Bài: Ngày Từ Phụ

Et bilde fra drapet i Hønefoss denne uka inneholdt mer informasjon enn mediene først skjønte. En bauta i norsk utenriksjournalistikk takker av. Æresgjest: Per Olav Ødegård, VG-journalist! Med Anders Giæver og Gard Steiro. Produsent Andreas Røen Pettersen og Magne Antonsen. Ansvarlig redaktør Gard Steiro. Kontakt redaksjonen på giaeveroggjengen@vg.no. Giæver & gjengen gir deg de viktigste nyhetene hver dag på drøye 20 minutter når du skal hjem fra jobb. Hør «Mediebobler» hver lørdag om feilene pressen gjør og dilemmaer VG står i. Hør «Skartveit» med interessante personer om aktuelle temaer hver søndag. Alltid på Podme.

Bí Quyết Trở Nên Giàu Có Của Người Do Thái - Phần 2: Kiếm Tiền Là Tốt Lành Diễn Giả: Rabbi Daniel LapinDịch và lồng tiếng: Ánh Sáng Nơi Thương TrườngMọi người thường hay bị ảnh hưởng bởi niềm tin rằng kiếm tiền là xấu xa, rằng khi kiếm tiền thì tức là chúng ta đang lấy đi của mọi người, trong bài học này Rabbi Daniel Lapin chứng mình cho chúng ta thấy tiền bạc là thuộc linh và kiếm tiền là tốt lành như thế nào.Rabbi Daniel Lapin là một học giả Do Thái người Mỹ gốc Nam Phi, sinh ngày 1 tháng 1 năm 1947 tại Johannesburg. Ông nổi tiếng với biệt danh "Rabbi của nước Mỹ" nhờ những đóng góp trong việc giảng dạy tri thức Do Thái cổ đại và kết nối các giá trị Do Thái - Cơ Đốc trong đời sống hiện đại.The Workplace Ministry (Muc Vu Noi Lam Viec) Youtube channel provides inspiring sermons and messages from Christian speakers, specifically designed to uplift and support the Christian community within Vietnam's professional landscape, where resources for Christian teaching are often limited. As a non-profit initiative, our mission is to offer encouragement and spiritual guidance for believers striving to serve God in their workplaces.Please note that some videos may not have obtained formal copyright permissions prior to translation. We appreciate the understanding and forgiveness of copyright holders. If you have any concerns, please do not hesitate to contact us at mygenvn@gmail.com.Thank you for your support!#RabbiDanielLapin #kinhdoanh #anhsangnoithuongtruong #dothai #giauco #kiemtien

Bí Quyết Trở Nên Giàu Có Của Người Do Thái - Phần 2: Kiếm Tiền Là Tốt Lành Diễn Giả: Rabbi Daniel LapinDịch và lồng tiếng: Ánh Sáng Nơi Thương TrườngMọi người thường hay bị ảnh hưởng bởi niềm tin rằng kiếm tiền là xấu xa, rằng khi kiếm tiền thì tức là chúng ta đang lấy đi của mọi người, trong bài học này Rabbi Daniel Lapin chứng mình cho chúng ta thấy tiền bạc là thuộc linh và kiếm tiền là tốt lành như thế nào.Rabbi Daniel Lapin là một học giả Do Thái người Mỹ gốc Nam Phi, sinh ngày 1 tháng 1 năm 1947 tại Johannesburg. Ông nổi tiếng với biệt danh "Rabbi của nước Mỹ" nhờ những đóng góp trong việc giảng dạy tri thức Do Thái cổ đại và kết nối các giá trị Do Thái - Cơ Đốc trong đời sống hiện đại.The Workplace Ministry (Muc Vu Noi Lam Viec) Youtube channel provides inspiring sermons and messages from Christian speakers, specifically designed to uplift and support the Christian community within Vietnam's professional landscape, where resources for Christian teaching are often limited. As a non-profit initiative, our mission is to offer encouragement and spiritual guidance for believers striving to serve God in their workplaces.Please note that some videos may not have obtained formal copyright permissions prior to translation. We appreciate the understanding and forgiveness of copyright holders. If you have any concerns, please do not hesitate to contact us at mygenvn@gmail.com.Thank you for your support!#RabbiDanielLapin #kinhdoanh #anhsangnoithuongtruong #dothai #giauco #kiemtien

Cory improved digestion, sleep quality, body composition, sun tolerance, and regulated hunger with a carnivore diet.  Timestamps: 00:00 Trailer 00:38 Introduction 05:11 Ketogenic diet and GI distress 07:12 Improved sleep on carnivore diet 12:55 Golf and mental resiliency 18:38 Human weaning patterns and brain size 23:05 Weight fluctuations on carnivore diet 25:23 Cyclical dieting with fat reloads 30:16 Sharing diet advice 36:27 Sun exposure and tolerance 40:09 Dabbling with dairy Join Revero now to regain your health: https://revero.com/YT Revero.com is an online medical clinic for treating chronic diseases with this root-cause approach of nutrition therapy. You can get access to medical providers, personalized nutrition therapy, biomarker tracking, lab testing, ongoing clinical care, and daily coaching. You will also learn everything you need with educational videos, hundreds of recipes, and articles to make this easy for you. Join the Revero team (medical providers, etc): https://revero.com/jobs ‪#Revero #ReveroHealth #shawnbaker  #Carnivorediet #MeatHeals #AnimalBased #ZeroCarb #DietCoach  #FatAdapted #Carnivore #sugarfree Disclaimer: The content on this channel is not medical advice. Please consult your healthcare provider.

Broadcast from KSQD, Santa Cruz on 6-12-2025: Dr. Dawn opens with alarming news about NIH budget cuts devastating cancer research just as breakthrough CAR-T cell therapy shows promise for gastrointestinal cancers. This personalized immunotherapy extracts patients' T cells, engineers them to target specific cancer antigens, and makes them essentially immortal before reinfusion. While previously successful only for blood cancers like leukemia and lymphoma, researchers achieved tumor shrinkage in 25% of solid GI tumor patients. However, devastating layoffs forced removal of two patients from trials due to staff shortages and supply chain disruptions. Dr. Dawn emphasizes how pregnancy can worsen hidden cancers due to immune suppression, explaining why aggressive metastasized cancers often appear shortly after childbirth. Dr. Dawn takes a call from Bob about concerning forehead growths his dermatologist examined. She speculates they're likely seborrheic keratoses - benign, stuck-on appearing growths common in sun-exposed areas that look like crumpled brown paper "spit-wads". These aging-related changes are harmless and can even be picked off, though she warns against repeatedly traumatizing any skin area as this increases cancer risk through accumulated DNA damage. She explains how repetitive trauma in occupational settings creates statistically higher cancer risks, comparing it to filling a bingo card of cellular errors. She addresses an email about Joe Tippens' cancer cure protocol involving fenbendazole, an anti-parasitic drug. Dr. Dawn explains this viral social media phenomenon began when Tippens claimed his lung cancer was cured by fenbendazole, but he was simultaneously receiving Keytruda immunotherapy at MD Anderson. The story spread rapidly in South Korea, causing pharmacy shortages. Unvalidated internet health information can spread dangerously. Dr. Dawn compares it to old-fashioned medicine show scams. trend Dr. Dawn warns about a recent vitamin B6 toxicity misdiagnosis trend affecting her patients who were told they had dangerous levels of B6 despite lacking neuropathy symptoms. Accuracy requires fasting 12 hours before blood draws, otherwise creating false elevations from recent vitamin consumption. More critically, she alerts listeners about biotin(Vitamin B7) interference with laboratory tests using biotin-streptavidin techniques. High-dose biotin supplements are often used in hair and nail health growth formulas. This can falsely alter tests for thyroid hormones, vitamin D, sex hormones, cortisol and dangerously, troponin levels that diagnose heart attacks. This could lead to missed myocardial infarctions in emergency rooms, potentially causing fatal outcomes. Dr. Dawn takes a call from Richard seeking information about a previous radio program guest. She guides him to use on-line resources at ksqd.org to find program details, pivoting into praise for libraries as community centers offering far more than internet access. She emphasizes libraries provide serendipitous discovery that algorithms can't match, encouraging people to explore their local library systems for events, historical collections, and personal assistance from knowledgeable librarians eager to help visitors navigate both physical and digital resources. She discusses the concerning trend of giving melatonin to children, calling it "the Grinch that stole children's bedtime." While used prescription-only for severe developmental disorders in Denmark and EU countries, American children receive melatonin gummies regularly, with one in five preteens using it occasionally. Dr. Dawn explains melatonin is a hormone affecting pancreas, heart, fat tissue, and reproductive organs still developing in children. Supplemental doses create blood levels 10 times higher than natural peaks, representing an uncontrolled medical experiment on developing brains and bodies. Poison control calls for melatonin ingestion increased 530% between 2012-2021, with one tragic case involving a three-month-old death where 20 melatonin bottles were found in the home. Dr. Dawn concludes by debunking food expiration date myths, explaining that Americans waste a third of food ($7 billion annually) due to misunderstanding labels. Most shelf-stable foods simply degrade in quality rather than becoming dangerous after printed dates. She notes acidic dairy products like yogurt resist bacterial contamination due to protective bacteria,and even surface mold can be scraped off safely. However, she emphasizes trusting expiration dates on lunch meats and deli products, which pose real listeria risks when stored improperly. California will soon simplify labeling laws to reduce confusion between quality and safety dates.

Tựa Đề: Hòn Đá Sống; Tác Giả: M. Jeudi; Loạt Bài: Hạt Giống Tốt

Tựa Đề: Người Chăn Chiên Hiền Lành; Kinh Thánh: Giăng 10:11-18; Tác Giả: Mục Sư Lê Thanh Liêm; Loạt Bài: Hội Thánh Báp-Tít Trung Tâm

Đại Lễ 18 Tháng 5, Ngày Khai Sáng Đạo Phật Giáo Hoà Hảo lần thứ 86, sẽ được long trọng tổ chức tại Hội Quán 91 Knight Ave, North Sunshine VIC 3019 Lúc 10:30 vào Ngày Chủ Nhật, 15 Tháng 6 Năm 2025 (Nhằm ngày 20 Tháng 5 năm Ất Tỵ).

Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/

Dagens episode kommer utelukkende til å handle om den nye eskalerte krisen i Midtøsten. Med Anders Giæver og Hanne Skartveit og Sindre Heyerdahl. Produsent Martin Frogner. Ansvarlig redaktør Gard Steiro. Kontakt redaksjonen på giaeveroggjengen@vg.no. Giæver & gjengen gir deg de viktigste nyhetene hver dag på drøye 20 minutter når du skal hjem fra jobb. Hør «Mediebobler» hver lørdag om feilene pressen gjør og dilemmaer VG står i. Hør «Skartveit» med interessante personer om aktuelle temaer hver søndag. Alltid på Podme.

Nghe Kinh Thánh Tân Ước Trong Ba Tháng: Giăng 21

Bài Giảng: Không Gì Có Thể Cướp Lấy Sự Bình An Của BạnDiễn giả: Mục sư Stuart OllyotChuyển ngữ: Đội ngũ Ba-rúcMục sư Stuart Ollyot, tác giả của cuốn sách "Preaching Pure and Simple" - (tạm dịch "Giảng dạy chân thật và giản dị"), nổi tiếng với những bài giảng sâu sắc nhưng vô cùng chân thành và giản dị của mình. Lời Chúa phán qua sứ đồ Phao-lô trong thư Phi-lip chương 4: 6-7 sẽ mở ra cho bạn cách thức để tiếp nhận và mãi mãi nắm lấy "sự bình an vượt quá mọi sự hiểu biết" của Đức Chúa Trời.-----------------------------The Giang Luan Kinh Thanh (Biblical Preaching) YouTube channel is dedicated to providing biblically faithful sermons and messages from respected Christian speakers. Our content is specifically designed to uplift and support pastors and believers in Vietnam, where access to resources for Christian teaching can be limited. As a non-profit initiative, our mission is to offer encouragement and spiritual guidance to believers striving to serve God in their communities.We would like to inform you that some videos may not have obtained formal copyright permissions prior to translation. We sincerely appreciate the understanding and forgiveness of copyright holders regarding this matter. If you have any concerns or inquiries, please feel free to reach out to us at giangluankinhthanh@gmail.com.---------------------------------Anh chị em có thể nghe bài giảng audio của Giảng Luận Kinh Thánh tại địa chỉ sau:Spotify: https://sum.vn/HybEqApple podcast: https://sum.vn/SccJBGiảng Luận Kinh Thánh là dự án dịch thuật/lồng tiếng sang tiếng Việt các bài giảng, thông điệp Cơ Đốc kinh điển của những diễn giả đã được thời gian khẳng định và cộng đồng Cơ đốc chung xác nhận. Đây là dự án phi lợi nhuận nhằm cung cấp nguồn tư liệu cho các tôi tớ cùng con dân Chúa tham khảo và sử dụng miễn phí. Để hiểu hơn về chúng tôi vui lòng truy cập website :https://giangluankinhthanh.net/Đội ngũ Giảng Luận Kinh Thánh hoan nghênh mọi đề nghị cộng tác của quý con cái Chúa khắp nơi trong các lĩnh vực như dịch thuật, lồng tiếng, quảng bá, cầu thay, v.v. Nếu quý con cái Chúa sẵn lòng đóng góp công sức của mình vào bất cứ lĩnh vực nào, cùng đồng công trong những sứ điệp giúp tỉnh thức nhiều người.Xin vui lòng điền thông tin cá nhân vào biểu mẫu sau: Kênh Giảng Luận Kinh Thánh hoạt động vì các mục tiêu phi lợi nhuận, không phát quảng cáo. Vì vậy, chúng tôi mong tiếp tục nhận được sự dâng hiến và ủng hộ của quý con cái Chúa khắp nơi trong việc phát triển kênh. Quý vị có thể dâng hiến theo thông tin trong biểu mẫu sau: https://sum.vn/ZZ19mNếu bạn muốn dâng hiến cho các hoạt động của Kênh, xin vui lòng chuyển khoản cho chúng tôi vào số tài khoản dưới đây:Tên tài khoản: Nguyen Thanh Tung - Nguyen Dinh HungSố tài khoản VND: 0010174709250 Số tài khoản USD: 0200143705194 Tên ngân hàng: Ngân hàng MB Bank – Chi nhánh Hoài Đức (Military Commercial Joint Stock Bank - Hoai Duc Branch)SWIFT CODE: MSCBVNVXXin chân thành cảm ơn!#Giangluankinhthanh #binhan #StuartOllyot #baigiangkinhthanh #baigiangtinlanh #sudiepcodoc

The Gi team return to talk Expedition 33, Elden Ring Nightreign, Summer Games fest, the Nintendo Switch 2 launch and more!

The Gi team return to talk Expedition 33, Elden Ring Nightreign, Summer Games fest, the Nintendo Switch 2 launch and more!

Send us a textWelcome back Rounds Table Listeners! Today we're introducing a new format—the first episode in our Trial Files series, where we provide an overview of a recent Trial Files issue. This week, Dr. Mike Fralick discusses three trials included in a recent throwback issue: opioids versus non-opioids for chronic pain; IV albumin for renal impairment and mortality; and omeprazole before endoscopy in patients with GI bleed. Three trials, 9 minutes, here we go!1. Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Trial (00:00 - 2:46)2. Effect of Intravenous Albumin on Renal Impairment and Mortality in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis (2:47 - 4:50)3. Omeprazole before Endoscopy in Patients with Gastrointestinal Bleeding (4:51 - 7:39)What is Trial Files?A free monthly newsletter on practice-changing trials, delivered straight to your inbox-- sign up here! (7:40 - 8:40)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textWelcome to the Hotflash inc Podcast! I'm Ann Marie McQueen, journalist and founder of Hotflash Inc, and today I'm joined by Dr Tiffany Duffing, PhD, a licensed clinical psychologist, US Army Veteran, and co-founder of GI Psychology. Dr Duffing is an expert in the gut–brain connection, integrative therapy and clinical hypnosis for GI disorders, chronic pain, insomnia, and anxiety. There is such an intersection with everything we are facing in perimenopause, so stay tuned as we dive into the science behind one of the most  practical tools for healing.HighlightsDr Duffing's path to GI Psychology and clinical hypnosisOvercoming skepticism: “If you don't show me the data, I'm gonna go collect some information.”Dr Duffing's personal experience with gut issues and family historyThe emotional and mental toll of GI distressPerimenopause, menopause, and the gut: what the research saysThe gut–brain connection explained: enteric nervous system, vagus nerve, and moreHow stress, trauma, and hypervigilance affect gut healthThe power of clinical hypnosis and how it worksSelf-hypnosis, apps, and how to find a qualified providerDr Duffing's advice: “If you have physical distress, Google Scholar that and see how clinical hypnosis can help. Boom.”Sponsor shoutout: Has your doctor told you that you're too young for peri/menopause, but you know you just don't feel like yourself? You're not alone – perimenopause can start earlier than you think. That's why MenoLabs is here, to support you with a range of products and the information you need to confidently speak up and get the care you deserve. They also offer science-backed solutions like their best-seller, MenoFit, a probiotic designed to help relieve symptoms like hot flashes and night sweats and more – all while supporting your overall health and wellness. Don't settle for less during this season of your life. Visit Menolabs.com and get the support you need today! Hotflash inc listeners get 20% off with code: HOTFLASH20Where to find Dr Tiffany:Website: gipsychology.comIG: duffing4gastrohealthLinkedIn: Dr. DuffingAmerican Society of Clinical Hypnosis (ASCH)Society for Clinical and Experimental Hypnosis (SCEH)Halfway To Dead, A Midlife Spiritual JourneyMidlife is freaking hard. Let's flip the script. Listen on: Apple Podcasts SpotifyJoin the Hotflash inc perimenoposse: Web: hotflashinc.comNewsletter: Hotflash inc. on SubstackTikTok: @hotflashincInstagram: @hotflashincX: @hotflashinc Episode website: Hotflashinc Listen on: Apple Podcasts | Spotify | Google Podcasts | YouTube | Substack See hotflashinc.com/privacy-policy for privacy information

Tune in to this engaging VetFolio Voice podcast episode with host Dr. Cassi and her guest, Dr. Alison Manchester, to learn about clinically relevant information applicable to dietary management of GI upset, including recent updates—from clinical research to real-life cases—that are commonly seen in practice. The conversation encompasses a review of different dietary strategies, including their potential mechanisms of action. Special attention will be paid to the impact of diet and other interventions on the gut microbiome. You'll also explore the differences in dietary interventions for dogs and cats and get tips for client communication tactics that help maximize compliance.

✅Link YouTube: https://youtu.be/abjb7XxBmbw Tham gia làm hội viên của kênh này để ủng hộ chúng tôi: https://www.youtube.com/channel/UCtoQh7mQikZsztA1OQRSFvw/join

Welcome to a Poetic Tea & Trails Podcast, This week brings a slight format shake-up, but nothing drastic, don't panic!Expect stories of epic Scottish mountain runs, unexpected GI battles, and a bit of dog poop too. But it's not all a struggle! There's ice cream fueled Swaledale Marathon fun, moments of triumph, and a bit of Strava inspiration to keep us all motivated. Also, our coaches talk about how do you track your running? Miles or time on feet?So lace up, breath & believe, and we hope you enjoy episode 125 of the Tea & Trails Podcast.XMILES UK - 10% discount via the link below.https://xmiles.avln.me/c/RiwxnARvfHeRRunderwear - Use code TEATRAILS15 for 15% off your orderhttps://runderwear.avln.me/c/GPVNMgMfYfLPSHOKZ - Use code TEA102025 to receive £10 off.https://uk.shokz.com?sca_ref=7394994.MfsDQZBAeLQihiPrecision Fuel & Hydration https://visit.pfandh.com/3GKxHjUPrecision Fuel & Hydration Planner https://visit.pfandh.com/3RuP25zHarrier - Use code TEA10 for 10% off. https://harrierrunfree.co.uk/Fenixlight Limited - Use code T&T5 for 5% off your order.https://www.fenixlight.co.uk/Protein Rebel - Use code Tea15 for 15% off your first order. https://proteinrebel.com/Centurion Running - Use code TEAANDTRAILS10 to receive 10% off *Excluding Sale Items.https://centurionrunning.com/GOODR - Use code GOTEAANDTRAILS to reveive 10% off your order.https://goodr.avln.me/c/VLEmsAIZCDtmLIFE JACKET SKIN PROTECTION - Use code GOTYOURBACK for 10% off your first order.https://lifejacketskin.com/PRIMUS UK - Use code TT-PRIMUS-20 for 20& off.https://primusuk.avln.me/c/kBWmOJaEiByDContent may contain affiliate links which can help support and grow this channel at no extra cost to you. Thanks for your continued support!Brew with the Coaches - CLICK HEREKeeping Dry & Staying Warm - https://amzn.to/42JCexqFix Your Feet - https://amzn.to/3FE4nf0Running Challenges by Keri Wallace - https://amzn.to/3KGdU7eROAR - https://amzn.to/3WU7xB2NEXT LEVEL - https://amzn.to/3Hu15LrUltra Trails - https://www.ultratrails.co.uk/Greener Miles - https://greenermilesrunning.co.uk/Hannah Walsh - https://www.hannahwalsh.co.uk/Punk Panther - https://www.punkpanther.co.uk/Pen Llyn Ultra - https://penllyn.niftyentries.com

Nghe Kinh Thánh Tân Ước Trong Ba Tháng: Giăng 20

Are you struggling with unexplained allergic reactions, chronic inflammation, rashes, fatigue, anxiety, or gut issues? You may be dealing with Mast Cell Activation Syndrome (MCAS)—a complex and often misunderstood immune system condition.In this episode of Root Cause Radio, functional medicine dietitian and hormone specialist Lacey Dunn and Anya Rosen dive deep into:What is MCAS and how it differs from histamine intoleranceCommon MCAS symptoms like hives, flushing, brain fog, IBS, POTS, and moreKey root causes including mold toxicity, chronic infections (like Lyme or EBV), SIBO, stress, and traumaHow to identify triggers and reduce mast cell degranulationThe best natural supplements and low-histamine diet tips to stabilize mast cellsHow to start to address gut health, detox , and nervous system dysregulationHere is a time-stamped outline of the key points discussed in the meeting, organized by minutes:0-1 minute: Introduction to the topic of mast cell activation syndrome (MCAS)1-2 minutes: Anya discusses the increasing prevalence of MCAS diagnoses and the differences between histamine intolerance and MCAS2-3 minutes: Lacey defines what mast cells are and how MCAS develops, as well as the differences between histamine intolerance and MCAS3-5 minutes: Lacey outlines the wide range of MCAS symptoms across different body systems5-7 minutes: Anya discusses the diagnostic criteria for MCAS7-8 minutes: Lacey and Anya discuss mold as a common root cause for MCAS8-9 minutes: Lacey identifies other potential root causes like infections, GI issues, genetics, and trauma/stress9-10 minutes: Anya emphasizes the importance of stabilizing the nervous system before addressing root causes10-12 minutes: Lacey and Anya recommend various natural supplements and medications for MCAS management12-13 minutes: Lacey cautions about potential side effects of certain supplements like quercetin13-15 minutes: Anya and Lacey discuss the role of lifestyle factors like reducing toxic exposures15-17 minutes: Lacey notes connections between MCAS, POTS, and Ehlers-Danlos Syndrome, and advises against what can hold you back from healing17-18 minutes: Lacey and Anya wrap up and encourage listeners to reach out for supportIdentifying root causes beyond just mold @ 15:07Emphasizing stabilizing the nervous system first @ 16:40Discussing connections to other conditions like POTS and EDS @ 30:09Need one on one help?Lacey's info:My Website & Work with Me: Instagram: ⁠www.instagram.com/faithandfit⁠⁠www.upliftfitnutrition.com⁠Email for coaching & phone consults: laceydunn@upliftfitnutrition.com & fitandfaith@gmail.comMy Supplement Company:Order my book "The Women's Guide to Hormonal Harmony" on amazon! Anya Rosen's info:Website: Instagram: Email: anya@birchwell.clinic

From constipation to hepatorenal syndrome. Fan favorite Elliot Tapper (@ebtapper, @ebtapper), gastroenterologist, transplant hepatologist, academic chief of hepatology, and director of the cirrhosis program at the University of Michigan, returns to answer a grab-bag of GI questions. Learn more at the Intensive Care Academy! Takeaway lessons

Send us a textIn this engaging conversation, Thomas and his guest Zach Smart discuss the deep love and commitment that comes with years of training. They delve into the infinite nature of jiu-jitsu, the balance between fun and fundamentals, and the importance of learning from failure. Zach shares his personal journey from aspiring MMA fighter to dedicated jiu-jitsu practitioner, emphasizing the community and camaraderie he found on the mats. The conversation also delves into the evolution of jiu-jitsu, comparing the technical aspects of gi and no-gi, and the future of the sport in terms of entertainment and professionalism. Here is the 250th episode of The RŌL Radio with a jiu-jitsu content creator and Black belt under Ross Nicholls at London Grapple, Zach Smart.www.rolacademy.tv 30% discount with ROLRADIO code at checkout. Over 1500 videos for your Jiu-Jitsu journey.FREE Access to ROL TV - https://rolacademy.tv/yt/269-the-rol-radiohttp://www.therolradio.comhttps://www.instagram.com/therolradiohttps://www.facebook.com/therolradio/https://www.instagram.com/zachsmart/?hl=enhttps://www.instagram.com/london_grapple/?hl=enhttps://londongrapple.co.uk/Episode Highlights:3:13 Loving Jiu-Jitsu Now More Than Ever5:27 Jiu-Jitsu is Infinite13:57 Finding the Balance Between Fun and Effort18:29 Making It Harder Than It Needs To Be20:23 Keeping an Open Mind22:33 Why Jiu-Jitsu27:50 The Resposibility of Learning32:06 The Structure and Freedom Within Jiu-Jitsu36:00 GI vs NOGI45:54 The Professional Future of Jiu-Jitsu52:45 Importance and Meaning of Promotions1:03:24 Zach Gets His Black BeltSupport the show

Struggling with GI distress during training or racing? You're definitely not alone and the good news is, it's fixable. In this episode, Bob and Dina break down the three main contributors to gastrointestinal issues and explore some of the nuances within each area. Whether you're dealing with bloating, cramping, or worse, this discussion will give you a clear starting point to identify what's triggering your symptoms and develop targeted strategies that actually work.Find Bob's “Metabolic Efficiency Training” 3rd edition book that we refer to in the episode here. -------Don't forget to subscribe to the podcast to get the free weekly episodes and also check out the YouTube channel.You can also support the podcast, help us to remain 100% ad-free, and get access to exclusive bonus content and behind-the-scenes conversations with Bob and Dina. Join our Patreon community or find us in the Patreon app by searching ISNPodcast.We'd love to connect with you on Instagram @isnpodcast and on Facebook And when you're ready to level up your health and performance even more, check out the services offered by Bob and Dina at their respective businesses.

Ilana Kersch was 31, healthy, and working as a dietitian—then she was diagnosed with hereditary stomach cancer and told she needed a total gastrectomy.In this powerful episode, Ilana shares what it's really like to live without a stomach—from managing dumping syndrome and rapid weight loss to navigating survivorship and identity after cancer. As both a clinician and a patient, her insights will change how you counsel your own.Whether you work in GI or not, this one will stay with you.Resources:Connect with AlanaMonash University 49 | The Biggest Cancer Nutrition Myths56 | Ask the Dietitian: Cancer Nutrition Strategies57 | Ask the Dietitian: Cancer Survivorship and NutritionAny Questions? Send Me a MessageSupport the showConnect with Colleen:InstagramLinkedInSign up for my FREE Newsletter - Nutrition hot-topics delivered to your inbox each week. Disclaimer: This podcast is a collection of ideas, strategies, and opinions of the author(s). Its goal is to provide useful information on each of the topics shared within. It is not intended to provide medical, health, or professional consultation or to diagnosis-specific weight or feeding challenges. The author(s) advises the reader to always consult with appropriate health, medical, and professional consultants for support for individual children and family situations. The author(s) do not take responsibility for the personal or other risks, loss, or liability incurred as a direct or indirect consequence of the application or use of information provided. All opinions stated in this podcast are my own and do not reflect the opinions of my employer.

Could neuroinflammation be driving your child's symptoms? This episode will change how you think about autism and health. In this two-part series of The Autism Dad Podcast, I sit down with Dr. Theoharis Theoharides, one of the world's leading experts in neuroimmune medicine and mast cell research. We dig deep into how inflammation in the brain—driven by overactive mast cells—can contribute to the struggles many autistic and neurodivergent kids face, including sensory issues, eczema, gut problems, chronic sinus issues, and even regression. Dr. Theo doesn't just talk theory—he shares actionable steps and science-backed insights that have the potential to improve quality of life for families like ours. I even share some personal stories about my sons, and how this research explains things we've experienced for years. Whether your child is dealing with eczema, unexplained aggression, or GI issues, this episode may offer a new lens on what's going on under the surface—and what you can do about it. In this episode, we discuss: What mast cells are and how they can impact the brain How neuroinflammation may be linked to autism, ADHD, and chronic conditions The surprising connection between eczema and autism Why symptoms like gut issues and behavior changes are often misunderstood The role of vitamin D, folinic acid, and glutathione in autism support How stress can trigger mast cell activation and impact behavior What testing and natural interventions parents can explore How to think critically about supplements and avoid misleading claims This episode is sponsored by Safe Place Bedding Safe Place Bedding provides medically necessary, insurance-covered safety beds that help neurodivergent children sleep safely and securely—at home or while traveling. They've just launched the Safe Place 300, a permanent safety bed option with integrated monitoring. Visit https://safeplacebedding.com/theautismdad to learn more. If you found this episode helpful, please subscribe on Apple Podcasts, Spotify, or your favorite podcast app. You can also visit listen.theautismdad.com for more episodes, resources, and to leave feedback.

Our guest this week is personal trainer, podcaster, and former Made in Chelsea star Ryan Libbey!When Ryan's partner Louise Thompson gave birth to their son Leo, she faced severe complications and trauma that turned their worlds upside down. We spoke to Louise last year on the podcast and now it's Ryan's turn to share his story. Ryan opens up to Gi about letting go of the pressure to always be the strong one in his family, and how showing up for himself was actually the key to showing up for Louise and Leo. Hosted on Acast. See acast.com/privacy for more information.

On today's episode of The Wholesome Fertility Podcast, I am joined by Hannah Davis (@rooted.with.hannah), a Registered Dietitian and certified meditation teacher who specialises in women's health, hormones, and autoimmune conditions. After being diagnosed with Hashimoto's while navigating early motherhood, Hannah shifted her clinical nutrition practice to focus on uncovering the deeper root causes of symptoms like fatigue, cycle irregularities, and PCOS. We dive into how nervous system dysregulation often underlies hormonal imbalances and why functional testing, mineral status, and emotional safety are crucial for true healing. From decoding PCOS types to understanding thyroid antibodies and the connection between trauma and calcium retention, Hannah offers a deeply integrative and compassionate lens for supporting women on their fertility and healing journeys. This conversation is packed with practical tools and fresh insights—don't miss it! Key Takeaways: PCOS is not just about ovarian cysts—it's a metabolic and inflammatory condition with many root causes. Nervous system regulation is foundational for hormone balance, digestion, and fertility. Functional lab testing (like Dutch and HTMA) reveals hidden patterns traditional labs may miss. Excess calcium in tissues may indicate trauma or over-supplementation with Vitamin D. Diet, stress, sleep, and gut health all influence autoimmune and hormonal symptoms. Guest Bio: Hannah Davis, RD (@rooted.with.hannah) is a Registered Dietitian and certified meditation teacher with advanced training in functional nutrition, lab testing, and spiritual psychology. She specialises in supporting women with hormonal imbalances, autoimmune conditions like Hashimoto's, and chronic fatigue through an integrative approach that blends clinical science with deep nourishment and nervous system healing. After navigating her own health challenges postpartum, Hannah now helps women reclaim their energy, resilience, and sense of safety through 1:1 coaching and group programs at Pivot Nutrition Coaching. She's especially passionate about working with mothers, self-healers, and cycle-breakers who are ready to feel like themselves again. Links and Resources: Follow Hannah on Instagram Visit the Pivot Nutrition Coaching website Book Mentioned: The Body Keeps the Score by Bessel van der Kolk   For more information about Michelle, visit www.michelleoravitz.com  To learn more about ancient wisdom and fertility, you can get Michelle's book at: https://www.michelleoravitz.com/thewayoffertility  The Wholesome Fertility facebook group is where you can find free resources and support: https://www.facebook.com/groups/2149554308396504/  Instagram: @thewholesomelotusfertility Facebook: https://www.facebook.com/thewholesomelotus/  Disclaimer: The information shared on this podcast is for educational and informational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health or fertility care. ------------- Transcript: # Audio: TWF 340- Hannah [00:00:00] [00:01:00] Welcome to the Wholesome Fertility Podcast. I'm Michelle, a fertility acupuncturist here to provide you with resources on how to create a wholesome approach to your fertility journey. **Michelle:** Welcome to the podcast, Hannah.  **Hannah:** thanks for having me. **Michelle:** So I'm very excited to have you on. We're gonna be talking about a lot of really cool topics, but before we get started, I always like to start out with kind of like an origin story and learn how you got into the work that you're doing.  **Hannah:** Yeah. I am a registered dietician. I've been mainly practicing medical nutrition therapy for the last 10 years in a more clinical setting. And you know, and then [00:02:00] I became a mom. I have two. One's almost eight, you gotta say almost eight. And the other one's, and the other one's nine. So they're really, they're really young and I, you know, working at the hospital part-time and I started noticing. **Hannah:** My own symptoms of, of things that just felt like off. And simultaneously I was also becoming more interested in learning about more integrative functional nutrition. And so that really led me down. It, it started off as, oh. A way for me to kind of figure out what was going on with me, because of course, like so many of my, the clients I work with now you know, you go to the doctors, you ask for some labs to be done and they just say, oh, you're absolutely fine. **Hannah:** You might just be stressed. You're stressed out, you're a young mom. Of course it's normal to feel exhausted all of the time and stuff like that. So, I just was like really interested [00:03:00] in doing more digging and so I, we got some training in advanced lab testing and more like integrative functional nutrition. **Hannah:** And so. From there I was able to figure out what's going on with me, and I, I actually have an autoimmune condition. It's called Hashimotos. And so that really affects, you know, your, your energy levels, your, your gut health, your immune system obviously is involved. So I, it was so incredibly validating and it really excited me. **Hannah:** I was like, I feel. If I can figure out a way to use advanced lab testing and combine that with my. More of my more clinical, you know, expertise and combine that together to really like, help women feel empowered about how to support their health and, and how they feel and their showing up in their lives every [00:04:00] day. **Hannah:** And so it just really, really excited me. So that's kind of what got me started with that. And then I, I pivoted towards, towards that about three years ago started my own virtual practice working more in like the women's health space. So like hormones, gut health, autoimmune conditions. **Hannah:** And then I, as I was doing more of that work, I was like, okay, there's. I'm seeing a common theme here. These women at their root, cause a lot of the time is nervous system dysregulation. And I got really. Tired of just saying over and over again. You know, you need to manage your stress a little bit better. **Hannah:** I wanted to be able to give them so much more than that. And obviously I knew that from my own journey. I really had to integrate that. And so, but I wanted to like, figure out how to help my, my clients integrate that. So then I became a certified meditation [00:05:00] teacher. And spent a year studying spiritual psychology, which is like a blend of Eastern ritual and practices with western psychology. **Hannah:** That, yeah. Yeah, yeah. So now I really like to supplement my, programs with giving my clients tools on how to regulate their nervous systems as well. And so, we'll, you know, you know, it's more of like life coaching almost. And then maybe we'll integrate some, some things like, meditation or breath work together. **Hannah:** It really just depends on what the, how the client wants to be supported. So  **Michelle:** Awesome.  **Hannah:** Yeah.  **Michelle:** You know it's interesting 'cause I  **Hannah:** Yeah. **Michelle:** an episode on. Nervous system. Really the vagal tone and  **Hannah:** Yes. **Michelle:** there's a link with a weaker vagal tone and things like endometriosis or  **Michelle:** PCOS, and I thought that was just fascinating. [00:06:00]  **Michelle:** So, yeah, I'd love to really kind of dig deep on all of these things. So just for people listening and they're kind of like hearing nervous system for the first time. 'cause well maybe they've listened to my podcast, maybe not when I talked about the nervous system. But what should people, like, explain the nervous system, explain how the nervous system ties into certain conditions. **Hannah:** I mean, that's a very, like, that's pretty broad because it's like, you know, it really depends on what. **Michelle:** the nervous system like tie into certain conditions?  **Hannah:** I don't know what condition it doesn't, honestly. Uh, the more, the more I get like deep in the weeds with this, so, you know, a lot of my clients we, you know, so I am typically working with people with autoimmune conditions and hormone. I balances gut health, that kind of stuff. And I, you know, I would say the nervous system impacts all of those areas [00:07:00] because ideally, especially when we're talking about women's health and like hormones, things like that we really just want to create safety in the body, right? **Hannah:** So that we can. Manufacture hormones and ovulate naturally and things like that. So, and then, you know, inflammation's another, another piece of that. It really just, it's a great way to, like, it just connects to everything right. **Michelle:** Yeah, well the vagus nerve is incredibly important when it comes to gut health. the stronger the vagal tone, the better the vagus nerve, the better. It's able to lower inflammation in the body.  **Hannah:** Mm-hmm. Mm-hmm. **Michelle:** fascinating and interesting. And so what are some of the things that you do suggest for people. they wanna regulate their nervous system and support that aspect.  **Hannah:** So First of all, I think it's important to just figure out what are the systems for that client? What are [00:08:00] the systems that are working for them and what's not? And really get really honest about that. And then, you know, it could be something like starting a. **Hannah:** Very doable meditation practice or some breath work like before, before meals, right? Getting into rest and digest me activating that vagus nerve so that we can digest our food properly. So it really just depends on what is feels a lot most aligned for the client and, and is doable for them. But also I think another big piece of this, which is not really talked about often is eating for blood sugar balance. **Hannah:** Because even like blood sugar swings throughout the day can cause fluctuations in your mood and your anxiety and cravings and all, all of, and even inflammation as well. So  **Michelle:** that  **Hannah:** like a whole body [00:09:00] approach. Mm-hmm. **Michelle:** It's such a good point. And I remember like looking into this and researching like just really the gut brain connection and. And it's interesting 'cause you can see it really go both ways. So if you have imbalanced gut microbiome that can ima impact your brain and your mood and your state and your emotions. **Michelle:** And it actually is linked with certain emotional um, imbalances or like mental disorders. It's really fascinating. And then they found. On the flip side that people who meditated for many years, like Tibetan monks, they had a really vast microbiome that was a lot more enriched and had a lot more diversity. **Michelle:** So it's really fascinating how you really can literally get it at both ends or either end.  **Hannah:** yeah. Like I tell my clients all the time, if you're breathing into your shoulders, the majority of the time it's gonna signal, [00:10:00] or that's gonna signal to the brain that you're in fight or flight. So it's gonna send all the blood to your extremities. It's not gonna be sending the blood to, you know, your, your GI track and your, you know, your organs there. **Hannah:** And so. it's gonna be a lot harder to digest your foods, whereas if you are really taking these deep breaths into your belly, it's sending all the blood there. And that's, that's a, and I mean, I often get skipped, you know, people are just like, no, just gimme a, just gimme a meal plan. I wanna feel better. **Hannah:** I wanna lose weight, or I wanna, you know, but it's like, you really gotta think about not just what you're eating, but how you're eating, like what your nervous system state is. You know, when you're, when you're eating food.  **Michelle:** That's so true. It's  **Hannah:** Mm-hmm. **Michelle:** true. And it was funny 'cause I was reading about that and it was one of the things to do is just stand. This is why they say like, don't drive and eat at the same time. Because when you're driving naturally, you're gonna be in a little bit more of a fight or flight or kind of ready for anything and. Also just to kind of throw it out [00:11:00] there, it's not bad to be in that state, in that sympathetic state. It's part of life. It's just that sometimes you need that and then sometimes you need the other. But what you're saying is so true, like it's actually like becoming mindful of getting yourself into that state and maybe  **Michelle:** doing those exercises to get yourself in more parasympathetic state, which is more of  **Michelle:** the rest and digest, so that you're priming your body when you do eat. To digest better. So I think  **Hannah:** Yeah. Of course, and, you know, if you're digesting better, you're absorbing nutrients better, which is gonna impact your energy levels, your mood, your hormones, everything. So yeah, there really, I feel like the more I get into it, the, more I see that there really isn't an aspect of our health, our med, our metabolic health, everything that is not touched by, your nervous system. **Michelle:** Yeah, it's really fascinating. I like, the more I dig into this, the more I'm just like so [00:12:00] amazed at how Willy, you know, it's the nervous system is kind of like this wiring of like. Information.  **Michelle:** It's almost like information that kind of signals to your body, all kinds of different states, but especially that safety. **Michelle:** I agree with you. You know, when you, when you feel safe, you can be more creative. And what does that mean really in the body fertility and it also regeneration growth.  **Michelle:** So yeah, it's pretty cool,  **Hannah:** Yeah. And I mean, hormones, that's how hormones work too. They're just chemical messengers in your body. **Michelle:** right? and so talk about PCOS, 'cause I know that you work with P-C-O-S-A lot just to cover. 'cause I think of people don't really understand it fully because it is you know, there's so many different types of PCOS and people get confused and sometimes people show PCOS symptoms, but then some doctors, and we don't know if they're just not like looking. Thoroughly into it. Dismiss it. Oh, that's not PCOS. So  **Hannah:** Right.  **Michelle:** that and just kind of, **Hannah:** Yeah.  **Michelle:** [00:13:00] it is,  **Hannah:** Okay, well, we'll just start what, like, so what is PCOS? So PCOS stands for polycystic ovarian syndrome. So a lot of people get confused by that right off the bat. They think, oh, so that mean I have cysts on my ovaries. Does that mean that I have it? So it's actually not a physical ovarian condition, like of the presence of cyst, but it's rather a hormonal condition and it's a, what I like to call a spectrum condition. **Hannah:** You know, 'cause there's different varieties and there's different root causes. It's important to understand, first of all what kind of PCOS you have and what the root causes are which is why we, we use functional lab testing in practice. But but yeah, I think a lot of women often it's like a long confusing road full of mixed messages of like just lose weight advice,  **Michelle:** Yeah,  **Hannah:** [00:14:00] you know. **Michelle:** really thin. PCOS patients, so that's where it can get so confusing for  **Hannah:** Right, right, right. And so, A-P-C-O-S isn't in an ovarian condition, you know, what exactly is going on? I mean, in a nutshell, it's basically, blood sugar issues plus inflammation, plus genetic susceptibility, which is going to lead to the ovaries to begin to produce large amounts of androgens. **Hannah:** So, you know, and I say genetic susceptibility because, you know, just because you have like insulin sensi or insulin resistance or diabetes, that doesn't mean you automatically are gonna get PCOS. Some people just have really sensitive ovaries right. And so they're, they're going to develop the, the condition, so I like to talk to my clients about well first of all, we start by running some tests [00:15:00] to find out, you know, what what their root causes are. And then we're gonna really go deep with, you know, working on the blood sugar issues with the inflammation, real food strategies lifestyle interventions, things like that. **Michelle:** One of the things that I find is pretty common just in my own practice, is that. **Michelle:** there's a huge link of gut imbalance  **Michelle:** or, you know, gut microbiome  **Michelle:** imbalance and inflammation, you know, that is part of the contributor to the inflammation and can really impact PCOS conditions.  **Hannah:** Yeah. Because you know, if we, if that inflammation in the gut is going unchecked you know, that's also gonna drive that insulin resistance even more.  **Michelle:** Yeah.  **Michelle:** what are some of the tests that you do for PCOS? Functional  **Hannah:** Well, yeah. Well, first of all, I, I like to start with a Dutch test. It's a, have you heard of [00:16:00] Dutch? The Uhhuh? Yeah. Oh, you do? Okay. Yeah. So I would run a Dutch you know, so that we,  **Michelle:** out just for people  **Hannah:** yeah. Yes, **Michelle:** I've never heard of it before. So it's dried urine testing for comprehensive, or I forget  **Hannah:** it's a Dr. It's a. Yeah, yeah. Dried urine test for comprehensive hormones. I know I used to think, oh, it's of Dutch, like it's from the Dutch, like, you know, but it's just an abbreviation.  **Michelle:** right, right.  **Hannah:** But yes, it's a very unique way to look at hormones. 'cause traditionally before this test was available, you would have to rely on blood work for hormones. **Hannah:** And, you know, saliva for cortisol, which is okay, but it's just not great. So this test really helps us get a lot more specific, a lot more personalized, and helps us get some answers that would probably. Be left unanswered if we were just, you know, looking at, at blood work alone. So, you know, it's gonna tell us, you know, give us a snapshot [00:17:00] of all three sex hormones, estrogen, progesterone, testosterone. **Hannah:** It's gonna show us how they're being metabolized in the liver. And then what I really like is it looks at your cortisol awakening response. So someone is struggling with sleep, mood, energy levels. Things like that that could also be driving your symptoms and, and your inflammation as well. So I, mm-hmm. **Michelle:** cortisol is your friend in the morning.  **Hannah:** Yes. Yeah. Yeah. And then I like that it also has that organic acid test at the end there, which some of those other markers are gonna be important for looking at, for hormone production. So it's nice if they include that. So I, I like to do a Dutch, I also like to do HTMA testing, which stands for hair tissue mineral analysis. **Hannah:** Because, you know, you know, when we're looking at hormones it's, you know, we, we also wanna be, look thinking about minerals too because and not just like, our minerals through blood [00:18:00] work, but more on a cellular level. Like what is the body doing with those minerals? And how is your body utilizing them? **Hannah:** Are they even getting up into the cell? So, and we can, you know, you know, minerals, they impact hormones, which means they're gonna impact PCOS. So I like that one too. And it's like a little, it's a, it's a nice way to, I like it 'cause it's, it shows your body's like, it's like a blueprint. It shows you your stress pattern. **Hannah:** know how your body is using minerals after you've maybe gone through a season of. Really high stress and you know, the fertility journey too is so stressful on its own that I'm like, yeah, let's look at what your body does with all this stress and how we can really like, you know, deeply nourish your body and, you know, make it feel safe for ovulation. **Michelle:** Yeah, I know that there's a lot of minerals that you can't really test in blood and for example, magnesium. That's a **Hannah:** Mm-hmm. **Michelle:** one to test for. So does this test for magnesium as well, like all [00:19:00] minerals or,  **Hannah:** yeah, yeah. It looks at all of the minerals. Specifically the ones that I'm gonna be focusing on. The minerals that impact PCS would be magnesium, zinc, calcium, iron selenium iodine. So, you know, and in a nutshell, you know, these, these minerals. they can exacerbate insulin resistance, hormonal imbalances, oxidative stress, which is important for like egg quality, sperm quality, things like that. **Hannah:** So women, get your men to your partner.  **Michelle:** Yes.  **Michelle:** So, so this is a hair test.  **Hannah:** yeah, it's a hair. They're using just like a teaspoon amount of your hair to analyze the mineral content in your tissues. **Michelle:** Fascinating. I know they've done those for like heavy metals and, and just testing the  **Hannah:** Yeah, yeah,  **Michelle:** I haven't heard of the mineral testing yet.  **Hannah:** yeah. And this, yeah. And this test does include heavy metals and we look at, mm-hmm.  **Michelle:** heavy metals. Oh, [00:20:00] okay.  **Hannah:** Mm-hmm. Mm-hmm. **Michelle:** it's really high. Just like for people that don't have symptoms sometimes I almost feel like it's like high for everybody.  **Hannah:** The heavy metals. Yeah. Yeah. You know, and  **Michelle:** somebody who's not, who doesn't have like,  **Hannah:** yeah, and I mean, we we're exposed to heavy metals all of the time. It's, you know, it's, there's, it's kind of impossible to get around it, you know? It's in our food, our water, the soil, you know. And so my approach is, you know, we might see like an acute. **Hannah:** Exposure to the heavy metals. But what we wanna see is that you, you're able to detox and excrete those heavy metals safely. You know, that's why, you know, we have our detox organs, our liver, right? And so if I ever see those metals like pushing into the tissues, it's just a really good indication that, hey, your liver needs some. **Hannah:** Some attention, like we need to work on supporting that. And also working on not just our [00:21:00] detoxification organs, but our drainage pathways. So like our lymphatic system you know, making sure we're having daily bowel movements that we're sweating all of that. All of that stuff. Yeah.  **Michelle:** Yeah. **Michelle:** for sure. I think that that's key is really detoxifying, and I think that it, you had a good point. You mentioned the word safely because  **Michelle:** that can be an issue, like if you detoxify too harshly. I'm really big on that, especially when you're trying to conceive and you're actively trying, you definitely don't wanna do something that's so strong that it actually circulates more toxins in your bloodstream.  **Hannah:** That's right. Yeah. **Michelle:** So they have like binders, right? Or things  **Hannah:** Yeah, That is one approach for me. I rarely will do like a heavy metal detox with somebody. I will just wanna work with them on, you know, first the foundational things of, are we optimizing the gut health, the, you know, the liver function are we getting those drainage pathways [00:22:00] open? **Hannah:** Because your body should be able to do all that on its own if it's, you know, optimal. but I mean, if someone's already doing like a gut protocol or something with me, then yeah, they, they'll be taking like those types of supplements and then it'll, it'll still act on the heavy metals and things like that, as. **Michelle:** Interesting. So, what are some of the nutrient and lifestyle interventions specifically that you would do for PCOS? Or have you seen, because I, I do know that  **Hannah:** yeah.  **Michelle:** different types, so that could  **Hannah:** Yes.  **Michelle:** the type,  **Hannah:** Yes. Yeah. **Michelle:** the things that people should kind of like look out for, think about?  **Hannah:** Yeah. Yeah. So the first step is, is gonna be improving the quality of your food choices. So, you know, removing inflammatory oils, added sugars a lot of like processed, like ultra processed carbohydrates and, you know, with chemical and artificial additives. Things like that, you wanna replace them with whole real foods. **Hannah:** It's really that simple.  **Michelle:** Yeah. I [00:23:00] know,  **Hannah:** Yeah. Yeah. And then also, you know, the goal is to eat a sufficient amount of carbohydrates to promote ovulation, but while still focusing on those whole real. Food sources, like starchy veggies fruits and then unprocessed whole grains and legumes.  **Michelle:** So really from natural sources,  **Michelle:** complex car carbs. So it's not like simple carbs, not white, you know, avoid those like.  **Hannah:** Yeah. Right. So you, and you would want to make sure you're getting adequate amount of carbohydrates, but you know, if we're also dealing with insulin resistance, then we also need to be talking about you know, maintaining adequate calorie intake and just aiming for. Balance across all the macronutrients. **Hannah:** So, you know, we're pairing those carbohydrates with good quality sources of protein and healthy fats. And, if you're eating a more whole food carbs diet like. Your carbs are coming [00:24:00] from fruits like, and like root vegetables and things like that, then those foods are naturally gonna have more fiber in them, which is also gonna help with things like insulin resistance. **Hannah:** And then I would also be focusing on gut nourishing foods, like, bone broth probiotics from fermented foods, cultured. Products. And then lots of prebiotic fibers. So it also just making sure you're eating a wide range of, plant fibers. Like we're not just eating the same, spinach every day. **Hannah:** You know, let's really mix that up. Maybe like arugula, kale, you know. So that would be the where, where I would start with foods strategies. And then for lifestyle I would be really focusing on exercise. This is a really crucial tool in repairing insulin sensitivity and managing blood sugar levels. **Hannah:** So first I would just focus on increasing your daily movement. So, you know, maybe try tracking your steps. And then maybe you would wanna consider adding in some resistance [00:25:00] training and some short hit style workouts. Since those really show the most metabolic improvements. In general I would avoid, I would avoid like, really long duration cardio on a regular baseball basis, since that's like very stressful on the body. **Hannah:** So exercise is number one. Stress management is key. I know we've already kind of touched on that a little bit. You know, that's a big piece of hormonal. Balance balance since the, your adrenal health, you know, has the ability to impact the function of your sex hormones. I would just evaluate the sources of your stress. **Hannah:** You know, I like to think of it like a bucket, like a stress bucket, and we have all these different inputs pouring in. Some of those things we can't really remove, but some things we can, you can control your nutrition and your sleep quality. You know, you can maybe work on energetic boundaries, right? **Hannah:** Maybe you wanna include things like meditation or [00:26:00] journaling, acupuncture, right? Those are all really nice ways to support yourself. And then sleep. Sleep is also like so major. That's when you know when you're, you can get good quality sleep at night. That's when your, your body's repairing tissue. **Hannah:** And it, it has a lot to do with your hormones, like in like your like your hunger hormones, those ones and then also like cortisol, melatonin, things like that. Everything that just keeps all of the systems working together smoothly. So, yep. Do you. **Michelle:** of sleep. There's a, there like a lot of times we'll increase sugar cravings 'cause you want that quick energy. So  **Hannah:** Yes, **Michelle:** that's one example of how that can impact  **Hannah:** exactly. Yeah. Yeah. If you have like one poor night of sleep, it increases your hunger hormone levels pretty significantly. So we'll see that that issue popping up time and time again. Yeah, so.[00:27:00]  **Michelle:** yeah. And I also have heard, in some  **Michelle:** of like go, literally pivot into autoimmune and how you can address that in the case of Hashimoto's? **Michelle:** 'cause it is so prevalent and a lot of people have it. The first thing that I say is, cut out gluten, corn, and dairy and soy if you can. Now, I always say if you can't do all of them, at least cut out the gluten entirely and talk to us about like what you've done and what you've found to be helpful. **Michelle:** 'cause it is something that if you catch early, you really can sh shift a lot just from diet alone.  **Hannah:** Oh, yes. Yeah, and I've helped. Hundreds of women with that. Exactly. Just you know, we [00:28:00] see, I've seen different stages of, Hashimoto's. You know, so if it's like, you know, stage one where we're seeing the presence of antibodies and maybe they have symptoms, maybe they don't. A lot of those women typically will present with like subclinical hypothyroidism. **Hannah:** So like their thyroid labs look fine. But they're like, I, feel tired all the time. I'm constipated. I can't lose weight, you know? So the first thing I would start with is kinda getting ahead of things with, 'cause the majority of your immune system is in your gut. So I would be doing a GI would run a stool sample, a GI map and see what's going on there. **Hannah:** Because there's different things that could be driving. That immune response. Yeah. It could be coming from things in the diet like gluten. And that test certainly will show us if you're having an immune response to gluten. So in those cases, I would have those clients cut, cut that out. And some people they, they don't, they don't run the test and they [00:29:00] cut out gluten, but they just feel better without it. **Michelle:** See that a lot.  **Hannah:** mm-hmm. I do too. Just kind of anecdotally. I was just gonna say that I think it is because of like, what, what they're spraying on our crops.  **Michelle:** Yeah, **Hannah:** Yep. know that it can impact hormones like big time, that's  **Hannah:** Mm-hmm.  **Michelle:** one for sure.  **Hannah:** Yeah. So, and then, you know, obviously if there's a inflammation or like leaky gut.  **Hannah:** You know, we're gonna wanna address that anyway because that could be driving that immune response and making your symptoms worse, making the antibodies levels worse, right? So I really wanna just get ahead of it with the gut number one. **Hannah:** And then I like to do mineral testing as well, since so many minerals, not only impact PCOS, but they impact your thyroid.  **Michelle:** That's a huge  **Hannah:** Yes, selenium. This is a common thing that I see. I'll see really high amounts of calcium in the [00:30:00] tissues. And that's gonna block your thyroid hormone from getting up into the cell. **Hannah:** So like maybe their thyroid panel looks great, but that, or they're already taking a thyroid medication, but they're, they feel like it's not doing anything for them. I'm like, look, you have a lot of calcium in your tissues. And so like, that's your thyroid hormone's not even getting up into the cell. So of course you wouldn't feel an impact there. **Hannah:** And that also is. **Michelle:** actually? What causes that? Calcification?  **Hannah:** So, I typically see that from over supplementing with vitamin D. So, that will pull the calcium out of the bone and teeth. And put it into the tissues. Yeah. A lot of people get put on vitamin D by their doctor, like maybe they had low levels at one point, and then their doctor never talked to them about weaning off of the vitamin D. **Hannah:** They just kept taking it.  **Michelle:** too high. Yeah.  **Hannah:** Yeah. Or they'll start them off like a really high dose, like I've seen like 50,000 units of, of vitamin. Yeah. [00:31:00] And they, and they just keep taking it like, then they're never told like, Hey, you're actually supposed to tapered off of that after a couple months. I've also seen an influx of people on vitamin D, zinc you know, ever since the pandemic. **Hannah:** So they just kept taking it and they don't know how that's impacted their. Mine. So, so yeah, that's one culprit. I, I'll see. The other thing that I notice, and this is pretty prevalent in the autoimmune community is, and I don't think it's talked about a lot, is significant trauma and certain types of trauma. **Hannah:** It, it's like we call when we see this pattern on an htm. It, we call it a calcium shell where the calcium and the magnesium levels are really high in the tissues. And then we are like really depleted in things like potassium and sodium and other secondary minerals. And it's kind of like the body's way of shielding itself from feeling [00:32:00] big, like feeling really big emotions. **Hannah:** So like a lot of these clients, I, I'll talk to them about this and they have such a flat effect, like with the then we start moving the calcium out of the tissues and then they become, they're, it's like they really need more emotional support throughout that process. It's very interesting. I'm about to actually do an HTMA on myself. **Hannah:** It's been a couple of years, but I've just gone, I'm grieving my mom right now and I, yeah, and it's just been a really rough couple of months. I've just been just going through the motions and kind of in that, like taking care of her, taking care of my girls. Like just everything that we've gone through leading up to this point. **Hannah:** And I'm like, I am so curious to know what's going on with my minerals right now. I would not be surprised if I was having calcium going into my tissues. 'cause I believe that's what was my pattern last [00:33:00] time I ran the test a few years ago. So.  **Michelle:** Oh, that's interesting.  **Hannah:** It's like, yeah, this is my, my unique pattern, you know, so I see that a lot with Hashimoto's and yeah, and, and it's interesting because that pattern, like the high calcium in the tissues and the low potassium, that's really really common with like thyroid stuff in general because, you know, first of all, that calcium's blocking the thyroid. **Hannah:** Hormone from getting up into the cell. It's also gonna be blocking insulin signaling. So there is gonna be a lot of blood sugar swings, and that's gonna be driving the inflammation, making that worse. And then the low potassium, well, you know, potassium is needed for thyroid function as well. So, I see that pattern a lot with that population and it's so fascinating. **Hannah:** And I would just say like, I wouldn't say it's like. It's more like anecdotal, right? Like and you probably see that too in your practice. Yeah. Yeah.  **Michelle:** For different things, not this [00:34:00] specifically, but Yeah. **Michelle:** I mean, you see a lot of that and that's, that matters just because studies are very expensive to have and you can't  **Hannah:** Mm-hmm. **Michelle:** rely just on studies. You have to really rely on data in general, like your own experience  **Hannah:** Oh, absolutely. **Michelle:** there's so much information that you can get just from that. And then, couple of things. One of the things is, I know that Zyme has been shown to really help, it's an enzyme, it's a pro oleic enzymes that break apart, like fibrous tissue. So I'm curious to  **Hannah:** Oh **Michelle:** if it would help with excess calcium or, you know, deposits because it, it works to break down  **Hannah:** yeah,  **Michelle:** really needed in the body.  **Hannah:** yeah. Yeah.  **Michelle:** up.  **Hannah:** Yeah. That is interesting. Yeah, because when we see, usually the calcium in the tissues is also associated with things like restless leg syndrome, kidney stones, gallstones, all that stuff, you know, because it's just calcification of the tissues. [00:35:00] Right. What I do is I'll get, if that person is, has actually been on vitamin D what I'll do is I'll say, okay, let's just pause on the vitamin D and then I'll get them on, a form of vitamin K two that will target that calcium in the tissues and, and bring it, redirect it back to the bones. So we'll do that for several months. And if that person's still concerned about their, their vitamin D levels and say, let's just get that checked, you know, and depending on where you're at with that, you, you either, you know, probably need supplementation time from time to time, or maybe just during the winter, right? **Hannah:** But it's not a long term. You know, supplement for you because of this pattern, this pattern that you typically have. **Michelle:** Another thing that I was gonna mention is, we were talking about like, antibodies.  **Michelle:** I remember, One of my patients mentioning she had like a, 'cause I was talking to an REI and I was gonna have him, I had him on the podcast and so she had some questions and she had a very low amount of [00:36:00] antibodies that are considered normal. And he said no, because the presence of any antibody, and that's what's crazy to me.  **Hannah:** Mm-hmm.  **Michelle:** normal in labs  **Hannah:** Yeah. Well, yeah. Yeah. The reference ranges for conventional labs or like in more like conventional healthcare settings. They're not, they're designed to show like if you have a chronic disease or not. Not necessarily if you're optimal. Right. Like thriving, you know? **Michelle:** have any, even if it's like minute, it means that there's an autoimmune, like  **Hannah:** Right. And.  **Michelle:** your thyroid.  **Hannah:** Yeah, and I mean, my first thought is like, and just because I've worked in that arena for so long, is I think it's just because they need to have a diagnose, a diagnosis for a chronic disease, number one, so that they can build insurance and blah, blah, blah.  **Michelle:** Yeah, yeah, yeah.  **Hannah:** So they typically can't treat you. They can't, they [00:37:00] technically can't treat you. **Hannah:** Like they don't really run on a, it's more of like a sick care model. It's not really, they can't really treat you for like prevention. Right. That's not like that that's not how insurance companies work. So, I think that that's, that's my theory on that. But, you know, but to, to answer your question, yes, I, I see, low levels that aren't considered Hashimoto's,  **Michelle:** Right?  **Hannah:** but I would label that early stages or stage one, and I would say, let's work, let's, let's order GI Map. **Hannah:** Let's look at what your minerals are doing like that impact your thyroid. Let's just, just start helping you feel better right away so that we can go into remission. I would much rather my client like, just go ahead and work on those things instead of waiting until it's like, you know, now we're seeing tissue damage, you know, and there's a lot of practices. **Hannah:** I don't,  **Michelle:** it if it's early enough, like, but if it's  **Hannah:** yeah.  **Michelle:** really like far gone,  **Hannah:** Yeah. It can, and I don't know if you've run [00:38:00] across this a lot in your practice or with your clients, but I've been told a lot of times that they weren't even able to request or see a specialist or an endocrinologist, I guess, until they were able to see tissue damage. And it's like, wouldn't you wanna just prevent the tissue damage? **Michelle:** crazy to me. Yeah.  **Hannah:** Mm-hmm. Yeah, so I'm, you know, I just like to get on it like right away, even if it's like, you know, your antibodies are like five, you know?  **Michelle:** yeah, yeah, yeah, yeah. Really low, but still,  **Hannah:** Yeah. Really low. Yeah. It's worth working on. Yeah. **Michelle:** I had actually just recently, I had a case where her TSH was like five and she's young, she's in her twenties. And I'm  **Hannah:** Mm-hmm.  **Michelle:** not normal.  **Hannah:** Mm-hmm. **Michelle:** just a little abnormal. **Michelle:** But that's not a little abnormal for try somebody trying to conceive.  **Hannah:** Yeah.  **Michelle:** and under. So if you  **Hannah:** Mm-hmm. **Michelle:** the thing. If you go to a general doctor or even an ob, they are a little more general in women's health.  **Hannah:** Yeah. **Michelle:** they're not going [00:39:00] to look at it the same way as an REI is gonna look at it, which is a reproductive endocrinologist and they're gonna  **Hannah:** Right.  **Michelle:** it a completely different perspective.  **Michelle:** Yeah, so it's, so those things I think a lot of people just don't realize and they're going in and they get the wrong information or they don't get like the full information and many years go by and it's kind of like, you know, that's why it's so important to really get ahead of it. **Hannah:** Yeah, absolutely. I think you're, you're worthy of feeling better, you know, if, does it have to be something that's chronic or.  **Michelle:** Right.  **Hannah:** Like full on disease state before just feeling better. **Michelle:** Yeah, for sure. So for people who, you know, are curious and wanna learn more about what you do,  **Michelle:** um, what are some of the things that you offer online? Where can people find you? I.  **Hannah:** So for people who are wanting to work one-on-one with me or maybe just start off with [00:40:00] a consultation or some have some labs done you can find me at through Pivot Nutrition Coaching. So the website is pivot nutrition coaching com. And then if, for my social media, I'm on Instagram with Hannah. **Michelle:** Awesome. I'll have all the notes anyway. If anybody like is curious or wants to know exactly how it's written out or find the link, you can find those on the episode notes. So Hannah, thank you so much for coming on today. It was a great conversation. I love really digging deep on just what goes on with these conditions that so many people hear about that are trying to conceive, but they don't really understand it. **Michelle:** And I think. There's so much power and knowledge and understanding and kind of like going beneath the surface. So I think this is one of the things that I like to do on the show is really to educate people on like really what's going on. So you've really shared some great, valuable information, so thank you so much, Hannah.[00:41:00]  **Hannah:** Thank you so much for having me and I, I think that this is such an important, important conversation to have and a valuable platform, so it's really an honor to be here. And hope we can chat again soon. **Michelle:** Thank you.