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Send us Fan MailOne tiny tick can change what you can safely eat for years, and sometimes the reaction doesn't show up until hours after dinner. From the Speaking of Women's Health Sunflower House, host Dr. Holly Thacker walks through summer health essentials, then goes deep on tick-borne illness and the fast-growing concern of alpha-gal syndrome, a red meat allergy that can follow a bite from the lone star tick and other species.She covers the practical stuff first: hydration and heat safety, UV protection for skin and eyes, smart ways to keep exercising in hot weather, mosquito control, and what to do (and not do) when poison ivy shows up. She also revisits water safety rules that saves lives, especially for children, including swimming lessons, life jackets, and why alcohol and water activities do not mix.Then she shifts to ticks: why people often never notice a bite, how ticks spread multiple pathogens, and why Lyme disease is still a major threat. She breaks down alpha-gal symptoms that can look “random” because they may appear two to six hours after eating mammalian meat or dairy, from hives and GI distress to swelling, wheezing, fainting, and anaphylaxis. Finally, she shares timely updates on new federal momentum to combat Lyme disease and accelerate alpha-gal research, plus intriguing early data on an unusual auricular allergy treatment approach that deserves careful study.Support the show
This week, we're so excited to welcome Lauren Cowell for her first ever podcast interview!After years of keeping a low profile while navigating public scrutiny, Lauren opens up to Gi about life after divorce, co-parenting, and how she handled the intense media attention surrounding her pregnancy with partner Simon Cowell.Lauren also shares more about her involvement in the ‘Raise the Age' campaign — and since recording this episode, Keir Starmer has announced plans for under-16s to be banned from social media by spring 2027
This episode is sponsored by Bluesky CBD and Alloy. Bluesky CBD: Get to sleep faster, experience more restorative sleep and save 30% with code FLIPPING50 at https://www.bluesky-cbd.com/discount/Flipping50. Alloy - Get your menopause treatment plan today. Visit https://myalloy.com and use code FLIPPING50 for $20 off your first order! #AgeGracefully Other Episodes You Might Like: Previous Episode - 25 Simple Rules for Optimal Health, Wellness & Fitness over 50 Next Episode - Muscle and Strength Loss Prevention After 50: A Checklist More Like This - What Is Sarcopenia and How to Avoid Sarcopenia In Menopause Resources: Get YOLKED with Fortetropin, a revolutionary supplement that helps fuel muscle growth and enhance recovery. Get powered by Mitopure®! The nutrient that can re‑energize cells with a breakthrough for healthy aging. Use code FLIPPING50 to claim your 20% discount. Collagen Boost is an unflavored source of bioactive collagen peptides designed to support skin and nails as well as healthy joints, bones, ligaments, and tendons. Use code PODCOLLAGEN10 to claim your 10% discount. Try the Lofta Home Sleep Test for sleep apnea in the comfort of your own home. Use Flipping 50 Scorecard & Guide to measure what matters with an easy at-home self-assessment test you can do in minutes. Muscle loss and sarcopenia have been synonymous with aging in previous generations. Muscle loss impacts osteoporosis, balance, stability, independence, and hormone balance. In this episode we'll talk about the 3 M's and how to bank muscle looking forward to a time off your fee as well as how to get it back if you have muscle loss and sarcopenia. My Guest: Dr. Chris Meletis is an internationally recognized educator, author, lecturer, and functional medicine practitioner with more than 33 years of clinical experience. He has authored 18 books and over 200 scientific articles, contributing extensively to the fields of naturopathic and integrative medicine. Formerly the Dean of Naturopathic Medicine and Chief Medical Officer at the National College of Naturopathic Medicine, he was honored as Physician of the Year by the American Association of Naturopathic Physicians. Passionate about accessible healthcare, he helped establish 16 free natural medicine clinics and continues to focus on the GI microbiome, mitochondrial health, nutritional biochemistry, and botanical medicine. Questions We Answer in This Episode: What trends have you seen in aging, and why does muscle become such a critical issue for women in midlife and beyond? Are physicians beginning to use muscle-related assessments as vital signs, and should strength be monitored more routinely as we age? What does grip strength actually measure, and why is it such a powerful indicator of overall strength and future health? What happens when you need a bunion surgery, joint replacement, or another procedure that temporarily limits activity? Will you lose muscle, and how can you prepare for it? If you're told to lose weight before a knee or hip replacement, how do you protect muscle mass while improving your health outcomes? Are we eating enough protein, and is our digestion allowing us to actually absorb and utilize it as we age? How can muscle-support strategies help during periods of bed rest, illness, pain, long COVID, or other situations that increase the risk of sarcopenia? What should active women do when they're already exercising but still struggle with maintaining muscle, energy, or lean body mass? If this episode made you flip your workout routine — share it!
BGVV-1766_Phụ Ái Mẫu Ái - Kỳ 3 Hồi Tưởng Cha Lành Tam Thuc Giac_Montreal, Canada_25-01-1980 Vô Vi Podcast-Vấn Đạo Vô Vi Podcast-Bài Giảng Vô Vi Podcast-Nhạc Thiền
The Gi crew discuss the new Titanfall 2 clone called Empulse, if you can be a fan without actually playing the game, Fable's new 30 minute demo, no wall bouncing in Gears, Xbox on the verge of collapse and more!
On this episode of the podcast, we are joined by BJJ Black Belt and former professional MMA fighter Josh Longood. Josh has gotten recent attention due to a video circulating of him apprehending a disruptive passenger on a flight. He shares his experience and gives an in-depth breakdown of how he was able to apprehend and control the passenger using his Jiu-Jitsu. Josh also discusses if anything has changed in his life since all of the social media attention, what level of Jiu-Jitsu skill was necessary to control the resisting individual, why Josh started training Jiu-Jitsu, why he quit fighting MMA, training sport vs. self-defense jiu-jitsu, competing in Gi vs. No-Gi, how to adjust training as you get older, rolling vs. drilling, and how you improve when rolling with less skilled grapplers. Thanks to the podcast sponsors: Datsusara, head over to https://www.dsgear.com/ and use the code Chewjitsu10 to get 10% off of the highest quality hemp gear for BJJ. Check out "Athlethc" at https://athlethc.com/ and use the code Chewjitsu10 to get 10% off of your order of hemp-derived THC performance mints. Charlotte's Web CBD. Head over to https://bit.ly/chewjitsu30 and use the promo code Chewjitsu30 to get 30% off of your total purchase. Epic Roll BJJ. Check out https://epicrollbjj.com/ and use the promo code Chewjitsu20 to get 20% off of your total purchase. Check out podcast exclusives including conversations with guests, Q&A sessions, and tons more at https://patreon.com/thechewjitsupodcast
In this episode of All Talk Oncology, host Kenny Perkins speaks with Dr. Shruti Patel, a GI medical oncologist from Stanford University, about the rising rates of early-onset colorectal and GI cancers and what they mean for patients today. Dr. Patel explains why more younger patients are being diagnosed, explores possible contributing factors like lifestyle and environmental changes, and emphasizes that there is no single cause of cancer. She also breaks down how clinical trials work, why patient advocacy matters, and how resources like clinicaltrials.gov can help guide treatment decisions. The conversation also dives into survivorship care and why life after cancer should be viewed as “life with a cancer history,” highlighting the ongoing physical, emotional, and financial challenges patients may face. In this episode, Dr. Patel discusses: The rising rates of early-onset colorectal and GI cancers Why younger patients are increasingly being diagnosed Possible contributing factors (diet, lifestyle, environmental influences) Why no single “smoking gun” explains cancer development How clinical trials work (Phase I, II, and III differences) Why patients should use clinicaltrials.gov and advocate for themselves The importance of second opinions in cancer care Why survivorship should be viewed as “life with a cancer history” Physical, emotional, and financial challenges after treatment The problem of patient guilt and blaming lifestyle choices Dr. Patel's insights offer a clear, compassionate, and empowering look into modern cancer care helping patients, caregivers, and clinicians better understand both the science and the human experience behind a diagnosis. Immortalize your voice by being an ALL TALK ONCOLOGY GUEST! Just fill-out this FORM. Invite Kenny Perkins to Speak or Participate on your event. Just fill-out this FORM. SOCIAL MEDIA LINKS: All Talk Oncology: Instagram & Facebook JOIN OUR FREE COMMUNITY: Facebook Community WEBSITE: www.alltalkoncology.com
This episode originally aired in 2025 and, as one of our most-loved conversations, we're sharing it again with you today.Today Erin and Sasha continue the exploration of the chakras with Manipura - the third of the seven chakras - which translates as “the shining sacred jewel.” It is associated with the Fire element, the planet Mars, the color Yellow, and the “Ishta Devata” Hanuman. It is located just above the navel and below the sternum, at our solar plexus — also called the celiac plexus — which is a complex system of radiating nerves and ganglia. It is found in the pit of the stomach in front of the aorta. It is part of the sympathetic nervous system and plays an important role in the functioning of the stomach, kidneys, liver, and adrenal glands. This chakra brings Prana to the digestive system, also known as our second brain. From a Western perspective, this is known and expressed as the gut-brain axis (or GBA) - the network of nerves and biochemical signals that connect the brain and the gastrointestinal (GI) tract. It's a two-way communication system that helps maintain homeostasis. The vagus nerve is one of the main nerves that connects the brain and gut, sending signals in both directions. From a clinical perspective, the GBA can impact disorders like irritable bowel syndrome (IBS), mood disorders, anxiety, depression, and memory loss. The GBA can also be linked to conditions like autism, obesity, schizophrenia, Parkinson's disease, and Alzheimer's disease. The Manipura chakra is directly linked to our sense of self, self-esteem, sense of purpose, the seat of clear decisive action, vision, dynamic action, assertiveness, discipline, determination, passion, deepest willingness to go beyond, strong will power, courage, resilience, and vitality. When balanced, there is energy and insight, will power and and follow-through, self-reliance, vitality and health. It can only be as balanced as the first 2 chakras. When imbalanced, there is a state of self-doubt, fear, insecurity, wanting, anger, blame, victimhood, depression, and lethargy. Positive affirmations, yoga postures that engage the core such as bow pose, cobra pose, or revolved triangle pose, and kapalabhati pranayama (or breath of fire) help strengthen Manipura when it is weak. We also get into ways of balancing an overactive Manipura, as Pitta-type individuals are prone to over exercising, overworking, and burnout. We hope today's conversation illuminates the ways in which we can reclaim and maintain our personal power, and that it is not as much a process of creating it, as it is discovering that which has always been there and removing what blocks us from experiencing it. Send us Fan MailThis episode is brought to you by Ojas Oasis Ayurveda, Sasha's private clinical practice. Schedule a 30-minute strategy session here. For 10% off Kerala Ayurveda, use code OjasOasis. For 20% off GarryNSun, code OJASOASIS20. For 10% off Ora Cacao, code OjasOasis10. Support the showTo learn more about working with us, please visit www.OjasOasis.com Connect with us @ojasoasis on Instagram, X, TikTok, and YouTube
The Gi crew discuss the new Titanfall 2 clone called Empulse, if you can be a fan without actually playing the game, Fable's new 30 minute demo, no wall bouncing in Gears, Xbox on the verge of collapse and more!
Welcome back to the Oncology Brothers podcast! In this episode we are joined by Dr. Neena Vijayvergia from Fox Chase Cancer Center to discuss the latest highlights from ASCO 2026, focusing on gastrointestinal (GI) studies. We discussed key studies: EMERALD-3 in HCC: Exploring the findings on combining TACE with Durvalumab and Tremelimumab, and the implications for patient outcomes. FIGHT-302 in Cholangiocarcinoma: The potential of FGFR inhibitors in frontline settings and the challenges of biomarker testing. CIRCULATE Update: The role of ctDNA in stage 2 colon cancer and how it influences treatment decisions. MATTERHORN Update: Benefits of perioperative chemotherapy and the importance of maintaining treatment regimens for better patient outcomes. We also touched on the evolving landscape of GI malignancies and the significance of multidisciplinary approaches in treatment planning. Tune in for an informative discussion that aims to enhance your understanding of the latest advancements in oncology and their practical applications in the clinic. Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o Apple Podcast: https://podcasts.apple.com/us/podcast/oncology-brothers-practice-changing-cancer-discussions/id1653340966 Follow us on social media: X/Twitter: https://twitter.com/oncbrothers Instagram: https://www.instagram.com/oncbrothers Website: https://oncbrothers.com/ Don't forget to subscribe for more updates on treatment algorithms, challenging cases, and conference highlights! #ASCO2026, #GIOncology, #ctDNA, #FGFRinhibitor, #OncologyBrothers
Can retatrutide finally be the breakthrough obesity treatment we've been waiting for? The answer is yes—and the data is stunning. In this episode I'm walking you through the biggest obesity medicine discovery from the ADA's 86th Scientific Session: retatrutide, a triple hormone receptor agonist showing weight loss results that rival bariatric surgery. You'll learn what makes retatrutide different from Wegovy and Zepbound, the stunning results from the Triumph 1 trial, what the side effects actually look like, and when this medication will finally be available. Weight loss medications are evolving faster than ever. But what you really need to know is what these results mean for your health. Listen now! Episode Highlights: Retatrutide is a triple hormone agonist that targets GLP-1, GIP, and glucagon receptors Participants lost an average of 28.3% of their body weight in 80 weeks Two-thirds of participants achieved a normal BMI—moved from obese to healthy weight Nearly everyone with prediabetes reversed it and returned to normal blood sugar Over 70% reduction in knee osteoarthritis pain and 60% reduction in sleep apnea severity The highest discontinuation rate due to side effects was only 11%—mainly GI issues Retatrutide is not yet FDA approved but anticipated to launch early 2027 Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
Tựa Đề: Cảnh Giác Với Ma Quỷ; Kinh Thánh: 1 Phi-e-rơ 5:8-11; Tác Giả: VPNS; Loạt Bài: Sống Với Thánh Kinh, Bài Học Kinh Thánh Hằng Ngày, Tĩnh Nguyện Hằng Ngày, Sống Với Thánh Kinh
Iran và Mỹ xác nhận đạt thỏa thuận hòa bình sau hơn 100 ngày xung đột. Giá dầu bắt đầu giảm khi thị trường kỳ vọng Eo biển Hormuz sẽ được mở lại và nguồn cung năng lượng toàn cầu ổn định hơn.
Tựa Đề: Cảnh Giác Với Ma Quỷ; Kinh Thánh: 1 Phi-e-rơ 5:8-11; Tác Giả: VPNS; Loạt Bài: Sống Với Thánh Kinh, Bài Học Kinh Thánh Hằng Ngày, Tĩnh Nguyện Hằng Ngày, Sống Với Thánh Kinh
BGVV-1765_Phụ Ái Mẫu Ái - Kỳ 2 Quy Hình Chơn Trạng_Montreal, Canada_19-01-1980 Vô Vi Podcast-Vấn Đạo Vô Vi Podcast-Bài Giảng Vô Vi Podcast-Nhạc Thiền
#Bàigiảng của Lm #GBPhươngĐìnhToại (MI) trong thánh lễ Kính trọng thể Thánh Tâm Chúa Giêsu năm A, cử hành lúc 19:00 ngày 14-6-2026 tại Nhà thờ Chính Tòa Đức Bà #TGPSG
Skaper AI et nytt klasseskille blant mediebrukerne, hvor mye må man egentlig betale for å slippe personrettet reklame i VG og det har vært mye debatt rundt mediedekningen av Marius Borg Høiby-saken, hvordan oppsummerer VG sin egen dekning? Med Gard Steiro og Anders Giæver. Produsent Simon Lynau. Ansvarlig redaktør Gard Steiro. Kontakt redaksjonen på giaeveroggjengen@vg.no. Giæver & gjengen gir deg de viktigste nyhetene hver dag på drøye 20 minutter når du skal hjem fra jobb. Hør «Mediebobler» hver lørdag om feilene pressen gjør og dilemmaer VG står i. Alltid på Podme.
#Bàigiảng của Lm #IgnatioHồVănXuân trong thánh lễ Kính trọng thể Thánh Tâm Chúa Giêsu năm A, cử hành lúc 17:30 ngày 13-6-2026 tại Nhà thờ Chính Tòa Đức Bà #TGPSG
Nghe Kinh Thánh Tân Ước Trong Ba Tháng: Giăng 21
Nghe Kinh Thánh Tân Ước Trong Ba Tháng: Giăng 21
#Bàigiảng của ĐGM #GiuseĐỗQuangKhang trong Thánh lễ Tạ ơn và cầu nguyện cho Tân Linh mục Gioan Bùi Hoài Bảo và Tân Linh mục Giuse Nguyễn Tiến Hải, cử hành lúc 9:30 thứ Bảy ngày 13-6-2026 tại Nhà thờ Giáo xứ Bình An.
Send us Fan MailKyle Peche became severely ill at the age of 18, when people should be filled with energy and good health. He was experiencing extreme brain fog, debilitating fatigue, severe constipation, GI issues, joint pain, skin rashes, and dozens of other symptoms. After many years of obsessive research, he finally found his way to health through systematic, step-by-step detoxification & Mineral-Balancing.Mineral Balancing is a holistic healing science that heals most ailments without the use of drugs. It uses Hair Tissue Mineral Analysis (HTMA) as a compass, which guides directions regarding precise supplement, detoxification, diet, and lifestyle recommendations based on the HTMA that move the body towards more balanced biochemistry, which maximizes the body's cellular energy. The body in turn heals itself, which causes not only elimination of symptoms, but also better quality of life!With a passion ignited from his own suffering, Kyle has now coached hundreds of people to higher health through proper full body detoxification & cellular rejuvenation.Find Kyle at-https://www.jyotimineralbalancing.com/IG- @kyle_pecheYT- @Jyoti Mineral BalancingTHE REJUVINATION ROADMAP MASTERCLASS! Sign up here for FREE!https://www.jyotimineralbalancing.com/masterclass-sign-upFind Boundless Body at-myboundlessbody.comBook a session with us here!
Giải vô địch bóng đá thế giới FIFA 2026 khởi tranh vào thứ Sáu hôm nay, với trận khai mạc diễn ra tại sân vận động Azteca huyền thoại, ở Thành phố Mexico. Giữa những tranh cãi về cách xử lý các vấn đề thị thực, mà các đội bóng và trọng tài gặp phải trước giải đấu, Chủ tịch FIFA đã bảo vệ cách giải quyết vấn đề này. Trong ba quốc gia chủ nhà, Mexico là quốc gia cuồng bóng đá nhất, nhưng vẫn có những tranh cãi về giá vé và những lo ngại về an ninh.
BGVV-1764_Phụ Ái Mẫu Ái - Kỳ 1 Chánh Tâm Trụ Hóa_Montreal, Canada_12-01-1980 Vô Vi Podcast-Vấn Đạo Vô Vi Podcast-Bài Giảng Vô Vi Podcast-Nhạc Thiền
Trump har erklært at han har en fredsavtale med Iran over 20 ganger, men denne gangen kan han få rett. Terrorfaren krigen har ført til, gjør at Hans Majestet Kongens Garde skal vikariere som politi i Oslo i sommer. SpaceX-noteringen på Nasdaq vil gjøre Elon Musk til verdens første dollar-billionær. Med Anders Giæver, Hanne Skartveit, Sindre Heyerdahl og Frøy Gudbrandsen. Produsent Simon Lynau. Ansvarlig redaktør Gard Steiro. Kontakt redaksjonen på giaeveroggjengen@vg.no. Giæver & gjengen gir deg de viktigste nyhetene hver dag på drøye 20 minutter når du skal hjem fra jobb. Hør «Mediebobler» hver lørdag om feilene pressen gjør og dilemmaer VG står i. Alltid på Podme.
Nghe Kinh Thánh Tân Ước Trong Ba Tháng: Giăng 20
Nghe Kinh Thánh Tân Ước Trong Ba Tháng: Giăng 20
#Bàigiảng của linh mục #GiuseTrầnHoàngQuân trong #thánhlễ kính Thánh Tâm Chúa Giêsu năm A, cử hành lúc 17:30 ngày 12-6-2026 tại Nhà nguyện Trung tâm Mục vụ #TPGSG
Un altro caso di cronaca nera riporta in primo piano il disagio mentale.Nel milanese, un uomo affetto da disturbi psichici, ha dato fuoco al padre. Già nel 2015 aveva provocato la morte di una persona per le conseguenze di un cazzotto sferratogli senza motivo.Ne parliamo con Alessia Cicolini, direttore delle Rems di Castiglione delle Stiviere (Mn) e Antonella Zarri, madre di Alice Scagni, uccisa dal fratello, Alberto Scagni.
VOV1 - Nhằm kịp thời tháo gỡ khó khăn, vướng mắc cho cộng đồng doanh nghiệp, ngày 11/6, Thuế tỉnh Đắk Lắk tổ chức “Hội nghị tuyên dương và đối thoại với người nộp thuế là chủ doanh nghiệp khối tư nhân năm 2026”.Toàn tỉnh Đắk Lắk hiện có 19.575 doanh nghiệp tư nhân đang hoạt động, kê khai và nộp thuế tại địa phương. Tại hội nghị, đại diện Thuế tỉnh Đắk Lắk đã phổ biến các nội dung mới về Luật Thuế thu nhập cá nhân, Luật Thuế thu nhập doanh nghiệp, Luật Thuế giá trị gia tăng; chính sách thuế đối với hộ kinh doanh chuyển lên mô hình doanh nghiệp; quy định nâng ngưỡng doanh thu chịu thuế của hộ kinh doanh lên trên 1 tỷ đồng; chuyển đối số thanh toán không dùng tiền mặt và một số nội dung liên quan khác.Nhiều doanh nghiệp nêu ý kiến, thắc mắc về chính sách miễn, giảm tiền thuê đất khi gặp rủi ro do thiên tai; việc kê khai trước kinh phí sửa chữa tài sản để khấu trừ trước khi hoàn thành sửa chữa tài sản; thủ tục xử lý hóa đơn khi bên mua không có nhu cầu sử dụng hoặc bị lợi dụng mã số thuế để xuất cho đơn vị khác nhằm trục lợi; và mức ưu đãi thuế khi chuyển từ hộ kinh doanh lên doanh nghiệp.Liên quan đến vấn đề nộp tiền thuê đất, ông Nguyễn Minh Cương, Giám đốc Công ty CP Vina Cà phê Sơn Thành, xã Sơn Thành, tỉnh Đắk Lắk, nêu kiến nghị: “Tháng 11/2025, các xã phía Đông tỉnh Đắk Lắk, trong đó có xã Sơn Thành, và công ty cà phê chúng tôi bị thiệt hại quá lớn. Riêng công ty chúng tôi bị thiệt hại trên 100 tỷ đồng, và đa số là tài sản của người lao động nhận khoán. Chúng tôi mong muốn đề xuất xin miễn, giảm tiền thuê đất cả năm 2025 thay vì chỉ miễn 4 tháng theo Nghị định 230/NĐ-CP. Và nếu duy trì mức hỗ trợ 4 tháng như hiện nay thì rất thiệt thòi cho người lao động.”Ông Nguyễn Anh Tuấn, Trưởng Thuế tỉnh Đắk Lắk, ghi nhận việc chấp hành nghĩa vụ thuế của nhiều doanh nghiệp trên địa bàn tỉnh. Trưởng Thuế tỉnh Đắk Lắk cho biết cơ quan thuế sẽ rà soát từng trường hợp miễn, giảm tiền thuê đất cụ thể, đối chiếu quy định hiện hành để giải quyết; trường hợp vượt thẩm quyền sẽ báo cáo UBND tỉnh, Cục Thuế hoặc Bộ Tài chính xem xét. Các vướng mắc phát sinh liên quan đến việc chậm phản hồi sẽ được cơ quan thuế làm việc trực tiếp với doanh nghiệp để kịp thời tháo gỡ.“Buổi đối thoại hôm nay nhằm giúp cho doanh nghiệp nắm được nghĩa vụ cũng như quyền lợi của mình trong lĩnh vực thuế. Đối với các doanh nghiệp mới thành lập, cơ quan thuế sẽ hướng dẫn để họ tự xác định mức thuế được ưu đãi, miễn giảm thụ hưởng. Ngành Thuế tỉnh cũng đang tập trung ứng dụng công nghệ thông tin trong công tác quản lý thuế nhằm giảm thủ tục hành chính, tăng tính minh bạch; trong đó, đẩy mạnh áp dụng hóa đơn điện tử, kê khai điện tử, hoàn thuế điện tử để hỗ trợ doanh nghiệp và người dân.”Dịp này, UBND tỉnh Đắk Lắk đã tặng bằng khen 7 chủ doanh nghiệp có thành tích xuất sắc trong thực hiện nghĩa vụ nộp thuế; Thuế tỉnh Đắk Lắk cũng biểu dương 43 trường hợp hoàn thành xuất sắc nghĩa vụ nộp thuế./.Tuấn Long/VOV Tây NguyênCán bộ thuế ở Đắk Lắk giải đáp thắc mắc liên quan đến Luật Thuế mới cho hộ kinh doanh và chủ doanh nghiệp tại phường Buôn Ma Thuột, tỉnh Đắk Lắk.Cùng với biểu dương, Thuế tỉnh Đắk Lắk đã tìm cách tháo gỡ những vướng mắc cho người nộp thuế là chủ doanh nghiệp tư nhân.
Laudetur Jesus Christus - Ngợi khen Chúa Giêsu KitôRadio Vatican hằng ngày của Vatican News Tiếng Việt.Nội dung chương trình hôm nay:0:00 Đức Thánh Cha gặp người di dân tại trung tâm “Las Raíces”13:48 Đức Thánh Cha gặp các tổ chức hỗ trợ hội nhập người di dân tại “Plaza del Cristo de La Laguna”28:25 Đức Thánh Cha chủ sự Thánh Lễ tại cảng Santa Cruz de Tenerife---Những hình ảnh này thuộc Bộ Truyền Thông của Toà Thánh. Mọi sử dụng những hình ảnh này của bên thứ ba đều bị cấm và dẫn đến việc đánh bản quyền, trừ khi được cho phép bằng giấy tờ của Bộ Truyền Thông. Copyright © Dicasterium pro Communicatione - Giữ mọi bản quyền.
We're dropping this bonus episode because something genuinely historic happened in oncology and we couldn't wait until our regular schedule to talk about it. Dr. Mark Lewis, GI medical oncologist, pancreatic cancer survivor, and one of our absolute favorite guests. He just got back from ASCO, the Super Bowl of oncology, where a new drug called daraxonrasib received one of only about six standing ovations in the conference's history, including applause that broke out mid-sentence when researchers showed the survival data on-screen. The drug targets a mutation that drives the vast majority of pancreatic cancer and has been considered "undruggable" for decades and it works not by attacking the mutation directly, but by cutting off the downstream signals it sends, like snipping the wire instead of fighting with the switch. The results are remarkable. In patients who had already received standard chemotherapy, daraxonrasib roughly doubled survival time and delivered it in pill form rather than an IV every two weeks, a meaningful quality-of-life difference for people who are already facing the hardest year of their lives. Mark walks us through the science, the side effects (rash, because RAS proteins live in skin too), the path to FDA approval, and what this means beyond pancreatic cancer, the same KRAS mutations show up in about 30% of lung cancers and 40% of colon cancers. Takeaways: Pancreatic cancer has been devastatingly hard to treat, 85% of patients are incurable at diagnosis because it spreads silently and there's no good screening, leaving most patients with a median survival of about a year on IV chemotherapy. KRAS, the mutation driving nearly all pancreatic cancer, was long considered "undruggable", the protein was so smooth and spherical that no drug could bind to it, and researchers were actively discouraged from pursuing it as a target. Daraxonrasib works by cutting the power rather than fighting the switch, instead of binding to the KRAS protein itself, it uses molecular glue to interrupt the downstream growth signals the mutation sends, an approach that took decades to develop and wasn't taken seriously until now. The trial results roughly doubled survival and the treatment is a daily pill, not an IV, patients who had already been treated with chemotherapy gained approximately an additional year of life with improved quality of life, which represents one of the most significant advances in pancreatic cancer treatment in decades. This breakthrough has implications far beyond the pancreas, KRAS mutations drive about 30% of lung cancers and 40% of colon cancers too, and proving the target is druggable opens the door to a new generation of treatments across multiple cancer types. Want more Dr. Mark Lewis? X: @marklewismd To Get Tickets to Wife & Death: You can visit Glaucomflecken.com/live We want to hear YOUR stories (and medical puns)! Shoot us an email and say hi! knockknockhi@human-content.com Can't get enough of us? Shucks. You can support the show on Patreon for early episode access, exclusive bonus shows, livestream hangouts, and much more! – http://www.patreon.com/glaucomflecken Also, be sure to check out the newsletter: https://glaucomflecken.com/glauc-to-me/ If you are interested in buying a book from one of our guests, check them all out here: https://www.amazon.com/shop/dr.glaucomflecken If you want more information on models I use: Anatomy Warehouse provides for the best, crafting custom anatomical products, medical simulation kits and presentation models that create a lasting educational impact. For more information go to Anatomy Warehouse DOT com. Link: https://anatomywarehouse.com/?aff=14 Plus for 15% off use code: Glaucomflecken15 -- A friendly reminder from the G's and Tarsus: If you want to learn more about Demodex Blepharitis, making an appointment with your eye doctor for an eyelid exam can help you know for sure. Visit http://www.EyelidCheck.com for more information. Produced by Human Content Learn more about your ad choices. Visit megaphone.fm/adchoices
HEALTH NEWS Ginger Supplementation Reduces Muscle Soreness, Review Finds Artificially sweetened and sugar-sweetened beverage intake and risk of liver cancer Plant-based quinoa burgers reduce post-meal blood sugar spikes Sleep and exercise may curb heart risk from mutant white blood cells Pregnant women may reduce key health risk through less sitting, more light exercise Ginger Supplementation Reduces Muscle Soreness, Review Finds Old Dominion University, June 4 2026 (Natural News) A review published in Nutrition Reviews found that consuming 2 grams of ginger daily for 11 consecutive days before exercise reduced delayed-onset muscle soreness (DOMS) by 23% to 25%. The review examined multiple placebo-controlled studies and found that single doses taken just before exercise did not produce significant pain reduction, but consistent daily intake over the 11-day period yielded measurable results. DOMS typically occurs 24 to 72 hours after exercise and is a common reason individuals skip subsequent workouts. In two placebo-controlled studies reviewed, participants consumed 2 grams of either raw or heat-treated ginger daily for 11 days before performing eccentric exercise, which lengthens muscles under tension. The effective dose identified in the review was 2 grams per day, roughly equivalent to one teaspoon of fresh grated ginger. Artificially sweetened and sugar-sweetened beverage intake and risk of liver cancer Yale University, National Cancer Institute, Boston University, June 10 2026 (Eurekalert) Are artificially sweetened beverage (ASB) and sugar-sweetened beverage (SSB) intakes associated with risk of liver cancer overall and by subtype (hepatocellular carcinoma [HCC] and intrahepatic cholangiocarcinoma [ICC])? In this pooled analysis of 11 prospective cohort studies comprising 1,518,411 adults, SSB intake per 1-beverage/day increment was associated with increased risk of HCC and ICC, whereas ASB intake was not associated with liver cancer overall or by subtype. There was no evidence of effect modification by diabetes status. Plant-based quinoa burgers reduce post-meal blood sugar spikes Federal University of Golas (Brazil), June 10 2026 (News-Medical) A study published in ACS Nutrition Science suggests that a plant-based burger made from baru pulp and red quinoa could reduce post-meal blood glucose responses in healthy adults. Red quinoa (Chenopodium quinoa Willd.) is a pseudocereal that is rich in protein, fiber, and micronutrients. It provide spolyphenols that have been shown to slow gastric emptying and overall digestion, and may reduce enzymatic degradation of carbohydrates in the gut. This would influence the rate at which glucose is absorbed into the bloodstream after a meal, altering the GI. The authors of this pilot study examined GI in a small sample of eight volunteers after consuming two plant-based burgers: one made with baru pulp and red quinoa, and the other with red quinoa alone. All three foods produced their highest blood glucose levels 30 minutes after consumption. The glucose reference food generated the largest peak at 174 mg/dL, while the baru pulp–red quinoa and red quinoa burgers reached substantially lower peaks of 118 mg/dL and 120 mg/dL, respectively. By 120 minutes, blood glucose levels had declined in all groups. Compared with the glucose reference, both plant-based burgers caused only modest increases in blood glucose relative to fasting levels: 15.5% for the red quinoa burger and 18% for the baru pulp–red quinoa burger. Sleep and exercise may curb heart risk from mutant white blood cells Mount Sinai Hospital, June 10. 2026 (Medical Xpress) Healthy sleep and regular exercise can work to counteract genetic mutations in white blood cells that are associated with cardiovascular disease and are most common among older people, Mount Sinai researchers have found. In a study published in Nature, the team reported for the first time that sufficient sleep and exercise can help reduce the cancer-like cell expansion and atherosclerotic risk linked to mutations that spontaneously occur in white blood cells. These mutations accumulate over our lifetimes and occur most often in hematopoietic stem cells, which are the cells in bone marrow that make blood cells, including macrophages and monocytes, immune cells that help defend the body. When these cells develop mutations, they start to proliferate, multiplying faster than they should, and become more inflammatory, irritating or damaging tissues in the body. This condition, known as clonal hematopoiesis (CH), is detectable in a quarter of people over age 70 and half of people over 80, though it is infrequent in young, healthy people. Healthy sleep and exercise was found to selectively influence immune cells with clonal hematopoiesis mutations, repressing their proliferative programming and expansion, as well as their ability to promote the formation of harmful plaque in the arteries of the heart. The findings reveal that CH mutant cells are malleable and selectively responsive to lifestyle behavior in a way that can mitigate atherosclerotic risk. Mount Sinai researchers discovered that moderate-to-vigorous physical activity was associated with a reduced incidence of gene-specific CH and fewer mutant cells in the blood. Sufficient sleep and exercise "turned off" the detrimental effects of rogue Jak2 and Tet2 mutant CH hematopoietic stem cells in the bone marrow, decreasing their ability to proliferate and grow, a precancerous process known as "clonal expansion. Pregnant women may reduce key health risk through less sitting, more light exercise University of Iowa, June 10 2026 (Eurekalert) Women who engage in light physical activity and lessen their sedentary time may significantly reduce the risk of key health problems during pregnancy, according to a new University of Iowa-led study. Researchers examined the daily behaviors of 470 pregnant women across all stages of pregnancy. Each participant wore a monitor that measured physical activity in 24-hour cycles and another monitor that recorded the time they spent asleep. Based on observational data collected from the study's participants, the researchers propose a “Goldilocks Day”-like guide for pregnant women that could reduce by nearly 30% the risk of developing hypertensive disorders of pregnancy (HDP), commonly occurring complications of pregnancy that include chronic hypertension, gestational hypertension, and preeclampsia. Those recommendations are: • Reduce sedentary time to fewer than eight hours each day. • Engage in light physical activity for at least seven hours each day. • Engage in approximately 22 minutes of moderate to vigorous physical activity, such as a brisk walk, each day. • Get nearly nine hours of sleep each night.
First, a huge congratulations to Grayson and her husband on the recent birth of their daughter, Violet! At the time of recording, she was just days away from becoming a first-time mom, and I couldn't be more excited for them.In episode 139 of The Eat for Endurance Podcast, I'm joined by professional trail runner and two-time World Mountain Running Champion Grayson Murphy.Grayson has dealt with her fair share of challenges as an athlete, including an eating disorder in high school, years of unexplained GI issues that ultimately led to a Crohn's disease diagnosis, performance anxiety, and most recently, training and fueling through pregnancy as a professional runner.Despite all of that, she has kept showing up to start lines, and winning, while learning how to fuel better, advocate for her health, and navigate the ups and downs that come with being human.Grayson and I discuss:Her transition from soccer to collegiate and eventually professional runningYears of unexplained GI symptoms, misdiagnoses, and the road to finally getting answersTraining and race-day fueling strategies, including for athletes with Crohn's diseaseTried and tested strategies to alleviate performance anxietyTherapy, medication, and other mental health tools that have helped herHer move from sub-ultra distances to the 50KTraining and fueling through pregnancy as a professional athleteWhether you're navigating a chronic illness, have felt dismissed by a healthcare provider, or want to fuel smarter and show up to race day with less anxiety, this episode is for you.
STRONGER BONES LIFESTYLE: REVERSING THE COURSE OF OSTEOPOROSIS NATURALLY
In this eye-opening conversation, Debi Robinson and Dr. John Neustadt expose a fundamental flaw in how we approach bone health: we've been focusing on bone density instead of actual fracture risk.Drawing from 20+ years of research and clinical practice, Dr. Neustadt reveals that only four nutrients have been proven in clinical trials to reduce fractures—calcium, vitamin D, vitamin K2 (MK-4 specifically), and magnesium. He challenges the one-size-fits-all approach to supplementation and explains why popular supplements like MK-7 and strontium fall short of their marketing claims.The episode deep-dives into why bone density tests are poor predictors of fracture risk, how supplement companies mislead consumers with marketing claims that don't align with clinical data, and the critical role of gut health, sleep, hormones, and lifestyle in fracture prevention.Most importantly, Debi and Dr. Neustadt provide actionable, evidence-based strategies that women can implement immediately to actually protect their bones—without fear-based messaging.WHAT YOU'LL LEARN✓ Why bone density scores are not reliable predictors of fracture risk✓ The 4 nutrients with clinical trial evidence for fracture reduction (and the doses that actually work)✓ Why MK-7 vitamin K2 doesn't improve bone strength (and why MK-4 does)✓ How to assess YOUR individual calcium needs (most women are over-supplementing)✓ The vitamin D target range for optimal fracture protection✓ Why strontium supplements mislead consumers (and the hidden risks)✓ The role of melatonin receptors in bone health and sleep deprivation's link to fractures✓ How gut health directly impacts bone strength✓ The importance of serotonin, melatonin, and the gut-bone axis✓ HRT and testosterone replacement as part of a comprehensive bone health strategy✓ How to evaluate supplement companies and ensure they have fracture outcome data✓ Red flags when choosing bone health supplements✓ The gap between conventional medicine's approach (DEXA + medication) and integrative bone health✓ Why doctors are confused about osteoporosis (and how to advocate for yourself)ACTION STEPSGet your vitamin D tested. Aim for 30–44 ng/mL for optimal fracture protection (different from immune health recommendations).Assess your dietary calcium intake before adding supplements. If you're eating well, you may only need 400 mg as a supplement, not the standard 1,200 mg recommendation.Switch MK-7 supplements to MK-4. If you're taking a vitamin K2 supplement, verify it's MK-4 at 45 mg per day in divided doses. MK-7 doesn't reduce fractures.Check your supplement labels for strontium. If it's there, especially if the company markets it as "proven to improve bone density," consider switching to a formula without it.Prioritize gut health. Work with a practitioner to run stool tests if you have bloating, constipation, postnasal drip, or other GI symptoms. Gut inflammation accelerates bone loss.Track your sleep quality. Sleep deprivation is linked to 17% of fractures. If you're sleeping less than 6 hours nightly, prioritize this.Ask supplement companies the right questions:"Do you have fracture outcome data from clinical trials?""Will you provide a certificate of analysis showing purity and potency?""What guarantee do you offer?"Evaluate your medications. Check with your doctor: Are any of your current prescriptions contributing to bone loss? (SSRIs, certain blood pressure meds, proton pump inhibitors, corticosteroids, etc.)Consider HRT or bioidentical hormone replacement, especially if you're post-menopausal. Research shows a 40% reduction in osteoporotic fracture risk with appropriate hormone therapy.Build lifestyle foundations: Prioritize whole-food nutrition, strength training, stress management, and community connection. Oxytocin (released through physical contact) supports bone health.RESOURCES & LINKSDr. John Neustadt's Website: nbihealth.com and book Fracture-Proof Your Bones: A Comprehensive Guide to OsteoporosisDebi's website: https://debirobinson.comHealthy Gut Healty Bones Program: https://debirobinson.com/healthy-gut-healthy-bones-program-v2/Join the Community: https://debirobinson.com/the-stronger-bones-lifestyle-community/Yoga Therapy MasterClass: https://debirobinson.com/yoga-therapy-for-bones-health-mc/28-Day Stronger Bones Method: https://debirobinson.com/28-day-stronger-bonesmorning-method/Instagram: https://www.instagram.com/debirobinsonwellness/Youtube Channel: https://www.youtube.com/@debirobinsonwellness/DEBI'S TAKEAWAY"Fracture-proofing your bones isn't about chasing a higher DEXA score. It's about building the internal biochemical balance that actually prevents fractures. You have the research, you have the tools, and you have the power to take control of your bone health naturally. Use that power."
Nghe Kinh Thánh Tân Ước Trong Ba Tháng: Giăng 19
Nghe Kinh Thánh Tân Ước Trong Ba Tháng: Giăng 19
Nghe Kinh Thánh Tân Ước Trong Ba Tháng: Giăng 19
Bài của Anh Cả Stephen W. Dyer, Thầy Bảy Mươi Có Thẩm Quyền Giáo Vùng, Giáo Vùng Châu Á của Giáo Hội Các Thánh Hữu Ngày Sau của Chúa Giê Su Ky Tô “Thưa Cha Thiên Thượng, Ngài có thật sự ở đó không? Và Cha có nghe và đáp ứng lời cầu nguyện của […] The post Podcast số 579 – Trang Mạng tháng 6, 2026 – Thượng Đế Nghe Những Lời Cầu Nguyện của Chúng Ta – Stephen W. Dyer appeared first on Thánh Hữu Việt Nam.
Are you an athlete or fitness enthusiast looking to maximize your performance, accelerate recovery, and break through plateaus?In this must-watch episode of the NASM “Peak Physique Podcast,” host Andre Adams (IFBB Olympian & NASM Master Trainer) sits down with expert Dr. Indy Vasquez to reveal the untapped power of gut health and its direct impact on metabolism and physique transformation.
The Original Southern Remedy is hosted by Dr. Jimmy Stewart, professor of internal medicine and pediatrics at UMMC. If you have a question for Dr, Jimmy, email it to remedy@mpbonline.org. In this episode, Dr. Jimmy talks about chest pain, GI tract issues and staying healthy during the hot summer months.If you enjoy listening to this podcast, please consider contributing to MPB. https://donate.mpbfoundation.org/mspb/podcast. Hosted on Acast. See acast.com/privacy for more information.
Một nghịch lý chấn động vừa được Nha Thống kê Úc (ABS) công bố: người dân quốc gia này hiện đang cảm thấy kém hạnh phúc hơn cả giai đoạn khủng hoảng năm 2020. Khi những rào cản giãn cách được gỡ bỏ, thứ chờ đợi họ không phải là sự tự do trọn vẹn, mà là làn sóng âm thầm của cuộc khủng hoảng chi phí sinh hoạt, lạm phát phi mã và sự sụt giảm tiền lương thực tế. Giờ đây, những góc khuất đầy áp lực, nơi việc duy trì cuộc sống thường nhật đang trở thành thử thách gian nan nhất.
This week Giovanna welcomes legendary singer-songwriter Laura Marling to the studio!Laura tells Gi about her early fears that becoming a mother might stifle her creativity, and shares her experiences of having two home births.She also discusses her mission to create children's music that parents can genuinely enjoy, and introduces her new venture, 'Laura Sings Raffi,' a 17-track cover album of beloved children's songs. Each song is brought to life with videos illustrated by Laura and animated by Rob Shuttleworth. Out now at Laurasings.co Hosted on Acast. See acast.com/privacy for more information.
Summary Ali Damron discusses the five pillars of hormone health, emphasizing a nuanced, personalized approach to women's health that integrates neuroplasticity, stress management, nutrition, and functional medicine testing. Key Topics The five pillars of hormone health: neuroplasticity, stress, nutrition, testing, and mindset The role of the nervous system in hormonal and overall health Limitations and benefits of functional medicine testing like Dutch test and GI map The importance of a personalized, nuanced approach over one-size-fits-all protocols The impact of stress, mindset, and perception on physical health and symptoms Takeaways Chronic symptoms often stem from neuroplastic and nervous system dysregulation, not just biochemical imbalances. Functional medicine testing can be valuable but should be used judiciously to avoid overwhelm and over-treatment. A neuroplastic approach can help treat chronic pain, anxiety, and hormonal issues by addressing the brain-body connection. Stress and perception of danger are central to hormonal imbalance; managing these can improve health outcomes. Healthcare should be personalized, with a focus on trust, validation, and understanding patient lifestyle and history. Sound Bites "The mind and body are not different." "Most symptoms are your body's communication." "Your brain perceives your world as dangerous." Chapters 00:00 Introduction to Hormone Health 02:46 Understanding Functional Medicine Testing 05:57 The Role of Stress in Health 08:49 Navigating Dietary Protocols 11:48 The Importance of Individualized Care 14:58 The Impact of AI on Healthcare 17:48 The Nervous System's Role in Health 20:59 The Interconnection of Mind and Body 23:47 Practical Approaches to Nutrition and Sleep 27:00 Conclusion and Call to Action Ali's Resources: Consults with Ali BIOptimizers Magnesium Breakthrough 10% off using code ALIDAMRON10 www.alidamron.com/magnesium Master Your Perimenopause Course + Toolkit "Am I in Perimenopause?" Checklist. What Hormone is Imbalanced? Quiz! Fullscript (Get 25% off all supplements) "How To Balance Your Hormones For Better Sleep, Mood, Periods and Energy" Free, On Demand Training Website Ali's Instagram Ali's Facebook Group: Holistic Health with Ali Damron
Host: Mindy McCulley, MS Extension Specialist for Instructional Support, Family and Consumer Sciences Extension, University of Kentucky Guest: Anna Cason, Senior Extension Associate, Polk-Dalton Clinic Season 8 | Episode 52 Join Talking FACS host Mindy McCulley and guest Anna Cason, Extension Associate with Family and Consumer Sciences, as they unpack the overlooked importance of fiber in the era of high‑protein trends. The episode explains what fiber is, why most Americans fall short (about 25 g/day for women and 38 g/day for men), and how fiber supports heart health, blood sugar control, digestion, and weight management. Anna offers practical, affordable tips: add fiber gradually and hydrate, choose plant proteins (beans, lentils, nuts, seeds, oats, quinoa) that supply both protein and fiber, favor whole fruit over juice, swap refined grains for whole grains, and use beans or oats to stretch meals. The episode also reviews a simple plate model for balanced meals and troubleshooting for GI discomfort when increasing fiber. Key takeaway: don't put one nutrient on a pedestal—aim for balanced meals that include fiber alongside protein for better overall health. Connect with FCS Extension through any of the links below for more information about any of the topics discussed on Talking FACS. Kentucky Extension Offices UK FCS Extension Website Facebook Instagram FCS Learning Channel
Trong kiệt tác “Kiêu hãnh và Định kiến”, Jane Austen đã khắc họa sống động 5 kiểu hôn nhân với những diện mạo và bản chất khác nhau. Qua từng câu chuyện ấy, bạn có thể cho mình thêm một góc nhìn sâu sắc hơn về những kiểu hôn nhân thường gặp. Và đó cũng là cơ hội tự vấn: Ta đang ở đâu và sẽ ở đâu trong những nấc thang hôn nhân ấy? Nếu tiếp tục lựa chọn như hiện tại, ta liệu có hạnh phúc hay chỉ quay lại với chính những vòng lặp khổ đau? Hy vọng những câu chuyện từ cuốn tiểu thuyết bất hủ này sẽ cho bạn những phút giây lắng đọng, để suy ngẫm, để tự vấn về tình yêu, về sự lựa chọn và về chính hạnh phúc của đời mình.Và bây giờ mời bạn cùng lắng nghe chia sẻ ngày hôm nay của Better Version-------------------------Nếu bạn muốn mua sách giấy để đọc, có thể ủng hộ Better Version bằng cách mua qua đường link này nhé, cám ơn các bạn! Link shopee: https://shorten.asia/GGtywzWMLink Tiki: https://shorten.asia/nzcgaVRM❤️ Link tổng hợp các cuốn sách trong tất cả video: https://beacons.ai/betterversion.vn/books ❤️ ỦNG HỘ KÊNH TẠI: https://beacons.ai/betterversion.donate
The Gi crew discuss all the major reveals from Summer Games Fest, State of Play, Xbox Showcase and every other showcase. Games such as God of War Laufey, Wolverine, FF7 Part 3, Metro 2039, Resonance Plaque's Tale, Onimusha, Spyro, Guild Wars 3 and more.
Dr. Spencer and Karl Nadolsky sit down with David W, a nurse practitioner and one of the actual patients enrolled in the Triumph 1 retatrutide phase 3 trial, to break down the data that was just presented at the American Diabetes Association conference and explain why everyone in obesity medicine is paying very close attention. In this episode they cover what retatrutide actually is and why adding glucagon agonism to the GLP-1 and GIP dual agonism of tirzepatide creates a meaningfully different drug with direct effects on liver lipid metabolism, insulin sensitivity, blood pressure, and fat catabolism that you do not see with semaglutide or tirzepatide alone, what David's personal experience in the 12 milligram arm looked like from dose escalation through steady state including the GI side effects that faded by month seven and the heartburn that a low dose PPI fixed quickly, how David went from 240 pounds and a BMI of 35 down to 167 pounds by the end of the trial representing roughly 30 percent weight loss which is right at the trial average, what the Triumph 1 obesity trial found at 80 weeks with the nine and 12 milligram doses delivering nearly 26 and 28 percent average weight loss respectively and almost half of patients on the highest dose losing 30 percent or more, why the 104 week extension data showing patients who stayed on 12 milligrams reaching 30.3 percent average weight loss is being compared to bariatric surgery outcomes, what the Transcend type 2 diabetes trial showed with average A1C dropping to 5.9 percent on the 12 milligram dose in patients who were on no other diabetes medication, why the 41 percent triglyceride reduction and 20 percent LDL reduction are particularly interesting given that the mechanism appears to involve multiple pathways in the liver that tirzepatide and semaglutide do not touch, what the 70 percent reduction in WOMAC knee arthritis pain scores and 60 percent reduction in sleep apnea events mean for patients who have been told their only option is surgery, how Spencer plans to use retatrutide clinically once it is approved and which patients he thinks are the right candidates, why the gray market research peptide version currently circulating is something both doctors strongly advise against, and what Triumph 2 and Triumph 3 are measuring and when that data is expected. The Docs Who Lift podcast distills and simplifies the complexities of exercise, medicine, and weight loss. Subscribe so you never miss an episode. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.