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Fecal transplants have become more and more popular in the gut health communities - especially for those with bowel diseases like Crohn's or colitis. But they can costs tens of thousands of dollars, and most of them don't work... but no one will tell you that. This episodes covers everything you need to know about FMTs, the pros, cons, risk factors and all the things no one has told you before. TOPICS DISCUSSED: What FMT is and how it's delivered to your gut How they came to be legal in the US Risk factors (people have died) What conditions they do and do not work on How to ensure an FMT actually works If you have Crohn's, Colitis or Diverticulitis, be sure to check out my second podcast: Reversing Crohn's and Colitis Naturally. Leave us a Review: https://www.reversablepod.com/review Need help with your gut? Visit my website gutsolution.ca to join a program: Get help now Contact us: reversablepod.com/tips FIND ME ON SOCIAL MEDIA: Instagram Facebook YouTube
Naturally Healthy Pets: Whole-Food Diets, Microbiome Repair, and Integrative Therapies with integrative veterinarian Dr. Judy Morgan, DVM, CVA, CVCP, CVFT. She argues that pet ownership benefits human wellbeing and that pets concentrate household toxins, warning against routine pesticide-based flea/tick and other veterinary drugs due to environmental contamination and adverse events. She recommends species-appropriate whole-food diets (cats as obligate carnivores; dogs mostly meat) and criticizes ultra-processed pet foods, synthetic nutrient premixes, grains/legumes in kibble, and high-carb diets that fuel yeast and inflammation; she discusses safe calcium, zinc, and vitamin D sources. In part two, she describes veterinary acupuncture, chiropractic, and laser/red-light therapies with case examples, links skin/ear “allergies” to gut dysbiosis, uses microbiome testing, FMT capsules, and detox support, highlights omega-3s, PEA for pain, and CBD for seizures/anxiety, and outlines multi-layered natural flea/tick prevention. Intelligent Medicine listeners can get 50% off Dr. Judy authored books found on NaturallyHealthyPets.com. Just use the coupon code INTELLIGENT50.
Once again @thejebaroo & @deeboiplays have been left in charge so they went rogue and did a live Q&A over on Jebs Twitch.Expect chats about FM World Cup Mode, FM What Ifs?Then questions with a very vast range, from a blind rank of FMT Hosts to best and worst movie, to which TNMT would be each FMT member, to whats the weirdest combo of food to lots of FM related and unrelated questions!It was a fun hour or so and we might threaten to do it again!https://tiktok.com/@deeboiplays - Deeboi's TiktokVIVA LA FMT! https//linktr.ee/fmtpod - All our Links
Welcome to Episode 307 of Autism Parenting Secrets. Many children struggling with neurological, immune, behavioral, and developmental challenges also show signs of significant microbiome disruption. Jason Klop from Novel Biome joins the show to explain why the microbiome may play a foundational role in overall health and why restoring missing microbes is becoming an increasingly important area of research and clinical care. As the CEO and Founder of Novel Biome, Jason has spent years focused on fecal microbiota transplantation (FMT), donor screening, microbial diversity, and the emerging science behind rebuilding the microbiome. In this conversation, we explore the connection between the gut and the brain, why probiotics often fail to create lasting change, what engraftment means, and how restoring microbial diversity may help support healthier immune and neurological function. The secret this week is… The Microbiome CAN Be Rebuilt You'll Discover: Why many children may be missing critical microbes entirely (9:36) The connection between microbiome disruption and neurological symptoms (2:04) Why probiotics often fail to create lasting change (20:12) What engraftment means and why it matters (25:21) Why rebuilding the microbiome may improve outcomes from other therapies (31:23) About Our Guest: Jason Klop is the CEO and Founder of Novel Biome, a Health Canada-licensed manufacturer of high-quality FMT products. A retired Naturopathic Doctor, Jason entered the FMT field in 2018 and has since built Novel Biome into a trusted source of on-demand fecal microbiota transplant products for clinicians, hospitals, and researchers worldwide. Website: https://novelbiome.com Additional Resources: To learn more about personalized 1:1 support go to www.elevatehowyounavigate.com Take The Quiz: What's YOUR Top Autism Parenting Blindspot? If you enjoyed this episode, share it with your friends.
Gut health is at the centre of so many health concerns, yet most women are still told to “eat more fibre” and move on. When symptoms like bloating, fatigue, and inflammation persist, it's often a sign there's more going on. I am talking to holistic nutritionist Nicole Inwentash about her personal journey with ulcerative colitis, the role of food sensitivities, and her experience with fecal microbiota transplantation (FMT). We also cover simple ways to support gut health, reduce overwhelm in the kitchen, and make realistic nutrition changes that actually stick. Nicole and I talk about: How early digestive symptoms like bloating and low energy can signal deeper gut issues• Why food sensitivities like gluten and dairy can significantly impact inflammation• What fecal microbiota transplantation (FMT) is and how it works in real life• Nicole's experience healing ulcerative colitis through FMT after conventional treatments failed• Why chronic stress and antibiotics can disrupt the gut microbiome• How to recognize when bloating is not normal and what to look for instead• Simple daily habits that support gut health including hydration, sleep, and movement• How to reduce processed foods without overhauling your entire lifestyle• Easy, realistic ways to make healthier swaps when cooking and baking at home• How to simplify meals by focusing on protein to reduce overwhelm for busy moms• Practical tips for feeding picky eaters while increasing nutrient density• How to make cooking feel easier and more enjoyable with simple recipes and batch prep Nicole Inwentash is a Toronto-based holistic nutritionist with over a decade of experience working with clients on digestion, weight loss, and overall health. She works in both clinical and private practice settings and is also a recipe creator focused on simple, gluten-free and dairy-free meals. Nicole shares practical nutrition strategies to help people feel better without overwhelm. Episode Links Follow Nicole on InstagramLearn more about Nicole and try her delicious recipes at Nutritiously Nicole Come say hi to me on Instagram Free Motherhood Manifestation: Your Vibrant Life Manifestation Books to thrive in Motherhood: Dive into The Motherhood Reset, Nourished Mama, and Mama Let It Go to overcome burnout and become a healthy, energized mom. Picky Eating Guide: Learn about common but lesser-known reasons kids are picky eaters and practical strategies to help children enjoy healthy foods. Resources I Am Loving Squat Seat – Comfortable seat to increase mobility and deep squat. Use code WILD5 for a discount. Ananda Elixirs – Delicious functional mushroom wellness elixirs. Get 20% off BON CHARGE – Red light devices. Get 15% off with the code: WILDANDWELL Fertility & Beyond – Natural solutions for your fertility struggles I would never recommend anything I don't regularly use myself or trust completely. Some of the links are affiliate links, and others are special discount codes. Either way, all of these are products and resources I genuinely love and recommend. Wild and Well with Dr Hilary Claire is a podcast dedicated to holistic health for moms, postpartum recovery, and children's wellness. We explore everything from functional health for women and gut health to pregnancy and postpartum wellness to nervous system regulation and motherhood burnout. Each episode offers practical tips for self-care for new moms, guidance on picky eating and parenting, and strategies to support your family's natural kids' health, so you can feel healthy, strong, and vital in motherhood.
Matters Microbial #128: C. diff from Nursery to Nursing Home April 20, 2026 Today Dr. Joseph Zackular, Assistant Professor of Pathology and Laboratory Medicine at the Perelman School of Medicine at the University of Pennsylvania, joins the #QualityQuorum to discuss some fascinating microbiology involving the bacterium Clostridiodes difficile (also known as C. diff), which can cause disease in infants, the elderly, and the immunocompromised. Host: Mark O. Martin Guest: Joseph Zackular Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An essay about siderophores in bacteria. The Giant Microbes "Cdiff" toy. The website of Dr. Patrick Schloss. A link to the #MattersMicrobial podcast with Dr. Schloss. An overview of Clostridioides difficile from a patient / physician perspective. A review article of research involving Clostridioides difficile. An overview on polymicrobial diseases. A wonderful opinion piece by Dr. Arturo Casadevall regarding the term "pathogen." An overview of Enterococcus in the gut microbiome. The technology of imaging mass spectrometry. An article on Stickland fermentation of amino acids among gut bacteria. Work by Dr. Zackular and colleagues discussed in this podcast, describing how FMT can be used as a treatment. Work by Dr. Zackular and colleagues discussed in this podcast, describing how different members of the host microbiome interact, and how that relates to disease. Work by Dr. Zackular and colleagues discussed in this podcast, describing the role of amino acid metabolism to changes in microbiome structure. Work by Dr. Zackular and colleagues discussed in this podcast, describing how Enterococcus can modulate the disease causing characteristics of C. difficile. An interesting paper showing that polymicrobial effects are more common than expected. An article arguing that there is no single "healthy" microbiome. A lovely primer on this topic for most nonmicrobiologists. An overview on fecal microbiome transplants and the treatment of human disease. The website for the Center for Microbial Medicine at the University of Pennsylvania. A great video by Dr. Zackular and colleagues, well worth your time. Dr. Zackular's academic website. Dr. Zackular's laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
The Perfect Stool Understanding and Healing the Gut Microbiome
Learn how the infant gut microbiome is shaped at birth, why many babies today are missing key Bifidobacteria and how it connects to eczema, food allergies and asthma. We discuss how delivery method, breast milk, antibiotics and early-life exposures influence immune development and long-term health, along with emerging research on restoring the infant microbiome through targeted probiotics and prebiotics, and FMT and cancer treatment. Lindsey Parsons, your host, helps clients solve gut issues and reverse autoimmune disease naturally. Take her quiz to see which stool or functional medicine test will help you find out what's wrong. She's a Certified Health Coach at High Desert Health in Tucson, Arizona. She coaches clients locally and nationwide. You can also follow Lindsey on Facebook, Tiktok, Instagram, Pinterest, Mastodon or X, or reach her via email at lindsey@highdeserthealthcoaching.com to set up your free 30-minute Gut Healing Breakthrough Session. Show Notes
Full Show Notes: bengreenfieldlife.com/fmt In this episode, you'll get to uncover one of the most intriguing developments in gut health—fecal microbiota transplants (FMTs). Joining me is Jason Klop, CEO of Novel Biome, who brings cutting-edge insight into how FMT is transforming from an obscure, hospital-based procedure into an accessible, precise, and surprisingly simple tool for optimizing your microbiome at home. We’ll break down how FMT is now being used for everything from irritable bowel issues to food sensitivities, and why the technology has advanced well beyond its origins. You'll also hear about the meticulous screening behind “super donors,” the science of oral FMT capsules, and the real-world results you can expect—including my own personal experience. Whether you’re looking to boost your gut health, support your immune system, or simply curious about the connection between your microbiome and overall vitality, this episode has what you need to stay on the cutting edge of holistic wellness. Jason Klop brings a clinical background in naturopathic medicine to his role as founder and CEO of Novel Biome, Canada's first licensed manufacturer of Fecal Microbiota Transplant (FMT) products. Having personally treated hundreds of patients with FMT in clinical practice, Jason saw a gap in the availability of safe, standardized microbiome restoration therapies and set out to build the infrastructure himself. Today, Novel Biome supplies FMT products to clinics, hospitals, and clinical trials around the world. Episode Sponsors: Take Ultra: Take Ultra is a clean, nicotine-free and caffeine-free pouch designed to deliver smooth, sustained energy and focus using clinically backed nootropics and adaptogens without the jitters, crashes, or sleep disruption. With flavors like their new Blue Razz, it’s a simple, effective way to stay sharp throughout the day. Visit takeultra.com and use code BENGREENFIELD for 15% off. Qualia Stem Cell: Qualia Stem Cell is a science-backed supplement designed to support your body’s natural repair system by enhancing stem cell function - helping you recover, renew, and maintain healthy tissues as you age. Taken just four days per month and formulated with premium, clinically supported ingredients, it’s an easy way to support long-term healing and vitality. Visit qualialife.com/boundless and use code BOUNDLESS for 15% off. Young Goose: Young Goose: To experience the transformative power of Young Goose's cutting-edge products, visit younggoose.com and use code BEN10 at checkout to enjoy a 10% discount on your first order. BlockBlueLight: BlockBlueLight: BlockBlueLight BioLights are the only lights extensively tested and recommended by building biologist Brian Hoyer as truly flicker-free, ultra-low EMF, and circadian-friendly, with three modes (day, evening, night) that support natural rhythms and optimize sleep quality. Get 10% off your first order at blockbluelight.com/Ben (discount autoapplied at checkout). See omnystudio.com/listener for privacy information.
Today, I'm joined by Dr. Grace Liu, often known as the “Gut Goddess,” a trailblazer in the world of microbiome science and founder of The Gut Institute. In this conversation, we take a bold dive into an often-overlooked pillar of longevity: your poop. That's right—Dr. Liu unpacks the fascinating and sometimes surprising science showing how gut health shapes everything from your immune system and brain to your lifespan itself. Episode Timestamps: Introduction to host ... 00:00:00 Dr. Grace Liu on the gut as a hallmark of aging ... 00:04:06 Peptides, FMT, and evidence for gut-driven regeneration ... 00:05:04 FMT safety, immune education, and the environmental “microdosing” effect ... 00:07:07 Links between gut aging, the immune system, and mental health ... 00:08:13 Diet, ancestry, and resistant starch for butyrate production ... 00:15:01 Ancestral diet, microbiome differences, and pitfalls of shortcuts ... 00:18:53 Fiber, polyphenols, and the key longevity bacteria ... 00:24:09 Gut markers, loss of diversity, and ABC species signature ... 00:25:15 Risks of overhyped probiotics, strep, and broad interventions ... 00:36:29 Peptides, bioregulators, and repairing the gut ... 01:12:01 Practical longevity: movement, daily habits & where to learn more ... 01:22:46 Our Amazing Sponsors: Tro Zzz by Troscriptions – A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Head to troscriptions.com and use code NAT10 for 10% off your first order. O₃RACLE by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off. CP1 Pure Collagen Peptides by Puori — a clean, unflavored collagen that supports connective tissue, joints, and skin elasticity with a unique amino acid profile your body actually uses, plus full third-party testing; go to puori.com/NAT and use code NAT for 32% off when you start a subscription. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode
Send us Fan MailWhat if one of the biggest reasons people stay stuck in chronic illness recovery is mold?In this episode of Never Been Sicker, Michael Rubino sits down with integrative medicine practitioner Michelle McKeon to talk about the overlap between mold exposure, Lyme disease, mast cell activation syndrome (MCAS), long COVID, immune dysregulation, and personalized treatment.Michelle shares why more patients today need customized care, how mold can suppress the immune system and complicate recovery, and why treatment order matters so much for sensitive people. Michael also explains why proper home investigation and remediation are essential if someone wants real, sustainable progress.In this episode, they cover:- Why mold is often a major missing piece in recovery- The connection between mold, Lyme, and MCAS- Why some people flare from supplements and detox protocols- How long COVID and environmental exposure may overlap- Why generalized testing and treatment often miss the full picture- How personalized care can help sensitive patients move forwardIf you've been dealing with mold illness, chronic inflammation, Lyme, long COVID, or MCAS, this episode connects many of the dots.Timestamps0:00 Intro0:31 Michelle introduces her background and work2:54 Personalized medicine and personalized remediation4:16 Why some patients need a more customized approach5:16 FMT and gut microbiome support for sensitive patients7:08 Blood cleansing therapies and lingering inflammatory burdens11:28 Michael asks about long COVID and indoor air quality13:10 Toxic bucket theory, mold exposure, and MCAS15:16 Why mold is a major factor for so many chronic illness patients16:58 The problem with poor inspections and bad remediation18:42 Why drainage pathways and sequencing matter in recovery21:18 Michael explains why center-of-room air sampling is flawed24:08 Why thorough remediation matters26:25 Why more patients now understand mold is serious28:13 Michelle shares her own experience with humidity and VOCs30:48 Looking at the body and home holistically31:14 The Lyme and mold connection34:47 Why aggressive treatment can backfire in sensitive patients36:58 Nervous system regulation and trauma in chronic illness37:23 The emotional cost of getting dismissed by doctors38:42 Do you need to treat mold before Lyme?40:38 Mold's impact on psychiatric symptoms and brain inflammation42:56 Mold, anxiety, depression, and root cause medicine47:00 What MCAS is and why it matters53:24 Michael asks the biggest lie Michelle has uncovered54:25 Michelle says the biggest lie is that mold is not that serious55:58 Michael explains why “mold is everywhere” is misleading1:05:22 Wrap-up and where to find Michelle-----------------------------------------------------------------------------------------------
In this episode of The Turd Nerds, the Turds are joined by Dr. Mark Davis, ND and we take a deep dive into the strange but powerful world of fecal microbiota transplantation (FMT)—what happens when you transplant an entire microbial ecosystem into the human gut and why it can be so effective for certain diseases. We explore why FMT is nearly curative for C. difficile, how dosing and delivery affect outcomes in ulcerative colitis and Crohn's disease, and share striking clinical stories of severe inflammatory bowel disease improving after repeated treatments. Music provided by Blue Dot.
Krunching Gears - The Rally Podcast. 2026 Season, episode 9. In this episode, we're joined by Niall McGonigle to reflect on his victory at the Fivemiletown Spring Stages Rally. We also review the Mayo Stages Rally with overall winner David Kelly, plus the two-wheel-drive victors Brian Lavelle and Jack Kelly. Finally, we look ahead to the upcoming Northern Ireland Rally Championship season with Championship Coordinator Gavin Campbell, discussing what competitors and fans can expect in the months ahead. Chapters Start 00:00:00 FMT with Niall McGonigle 00:02:20 Mayo - David Kelly 00:19:50 Mayo Brian Lavelle & Jack Kelly 00:28:50 NI Championship - Gavin Campbell 00:45:40 End 01:02:09
Hi gang!After a week of illness, FMT is BACK!Join Rich, Dee and Steaky as they talk you through what's been going on in their vitual worlds.This week, the FMTeam have a job on their hands - talking Rich down from the edge of the abyss. After news of Barry Bannan's impending departure has broken this wek, the gang talk losing a club legend, where you go next and how you cope when it happens on FM.We've also got a spicy FMT One Season Challenge update and a luttle bit of AFCON trivia.It's good to be back.God I'll miss Barry.VIVA LA FMT!Our links:https://linktr.ee/fmtpodhttps://twitch.tv/richowensfmhttps://twitch.tv/jebaroohttps://twitch.tv/deeboiplayshttps://twitch.tv/the_steak_bakeCupburger: https://www.cupburger.org#FMT #FootballManager #Football #Soccer #FM26 #FM
“They're kind of like a hidden superhero in your body and we just didn't know they existed. Muse cells eat the damaged cells, and they can actually turn into new cells using the cellular machinery.”Dr. Adeel Khan is a global thought leader in regenerative medicine. He is the CEO and Founder of and founder of Eterna Health, whose work with MUSE cell therapy—developed in collaboration with its discoverer, Professor Mari Dezawa—has made him the go-to expert for world leaders, athletes, and celebrities Chris Hemsworth, Kim Kardashian, and Tony Robbins. In this episode, we move beyond the hype of "anti-aging" to explore the hard science of Muse cells (Multilineage-differentiating Stress-Enduring cells). Dr. Khan breaks down how these unique cells differ from the "medicinal signaling cells" (MSCs) found in most clinics and how they act as a bridge to a future where tissue regeneration is standard care.(0:00) The "Repair Guys" & The Muse Difference Dr. Khan explains why traditional stem cells (MSCs) often disappoint and how Muse cells offer the "best of both worlds": safety and pluripotency.(2:19) Smart Cells: How They Find the Damage Understanding the "homing mechanism" that allows Muse cells to sense inflammation and instinctively travel to injured areas like the brain or heart.(3:11) Curing the Incurable: Diabetes & Alzheimer's The potential of the "cure triad"—stem cells, gene therapy, and FMT—to treat complex autoimmune diseases within the next decade.(4:40) Biological Noise & The Symphony of Health How "static" in our gene expression indicates aging, and how cellular therapy can reduce this noise to restore the body's harmony.(6:40) The Viral Monkey Study Dr. Khan discusses a recent study showing significant de-aging in monkeys through high-frequency cell dosing.(7:32) Unshakeable Foundations: Lifestyle as MedicineWhy advanced therapies must be paired with purpose, community, and mindfulness to create a "bulletproof" body.(8:44) From Sketchy to StandardizedNavigating the regulatory landscape: why Muse cells are being classified as a drug in regions like the UAE and the path toward FDA approval.(12:24) A Personal MissionDr. Khan shares the origin of his journey: trying to find solutions for his mother's chronic illness when traditional medicine failed.(14:16) The Cancer HunterUnlike other pluripotent cells that risk tumor growth, Muse cells have a unique mechanism that can detect cancer cells and trigger their death.(18:30)Future Outlook: AI, Nature & Blue Zones Reflections on the risks of AI, the importance of "Blue Zone" city design, and reconnecting with nature in a post-human world.Episode Websitewww.creativeprocess.info/podInstagram:@creativeprocesspodcast
The Creative Process in 10 minutes or less · Arts, Culture & Society
“They're kind of like a hidden superhero in your body and we just didn't know they existed. Muse cells eat the damaged cells, and they can actually turn into new cells using the cellular machinery.”Dr. Adeel Khan is a global thought leader in regenerative medicine. He is the CEO and Founder of and founder of Eterna Health, whose work with MUSE cell therapy—developed in collaboration with its discoverer, Professor Mari Dezawa—has made him the go-to expert for world leaders, athletes, and celebrities Chris Hemsworth, Kim Kardashian, and Tony Robbins. In this episode, we move beyond the hype of "anti-aging" to explore the hard science of Muse cells (Multilineage-differentiating Stress-Enduring cells). Dr. Khan breaks down how these unique cells differ from the "medicinal signaling cells" (MSCs) found in most clinics and how they act as a bridge to a future where tissue regeneration is standard care.(0:00) The "Repair Guys" & The Muse Difference Dr. Khan explains why traditional stem cells (MSCs) often disappoint and how Muse cells offer the "best of both worlds": safety and pluripotency.(2:19) Smart Cells: How They Find the Damage Understanding the "homing mechanism" that allows Muse cells to sense inflammation and instinctively travel to injured areas like the brain or heart.(3:11) Curing the Incurable: Diabetes & Alzheimer's The potential of the "cure triad"—stem cells, gene therapy, and FMT—to treat complex autoimmune diseases within the next decade.(4:40) Biological Noise & The Symphony of Health How "static" in our gene expression indicates aging, and how cellular therapy can reduce this noise to restore the body's harmony.(6:40) The Viral Monkey Study Dr. Khan discusses a recent study showing significant de-aging in monkeys through high-frequency cell dosing.(7:32) Unshakeable Foundations: Lifestyle as MedicineWhy advanced therapies must be paired with purpose, community, and mindfulness to create a "bulletproof" body.(8:44) From Sketchy to StandardizedNavigating the regulatory landscape: why Muse cells are being classified as a drug in regions like the UAE and the path toward FDA approval.(12:24) A Personal MissionDr. Khan shares the origin of his journey: trying to find solutions for his mother's chronic illness when traditional medicine failed.(14:16) The Cancer HunterUnlike other pluripotent cells that risk tumor growth, Muse cells have a unique mechanism that can detect cancer cells and trigger their death.(18:30)Future Outlook: AI, Nature & Blue Zones Reflections on the risks of AI, the importance of "Blue Zone" city design, and reconnecting with nature in a post-human world.Episode Websitewww.creativeprocess.info/podInstagram:@creativeprocesspodcast
“They're kind of like a hidden superhero in your body and we just didn't know they existed. Muse cells eat the damaged cells, and they can actually turn into new cells using the cellular machinery.”Dr. Adeel Khan is a global thought leader in regenerative medicine. He is the CEO and Founder of and founder of Eterna Health, whose work with MUSE cell therapy—developed in collaboration with its discoverer, Professor Mari Dezawa—has made him the go-to expert for world leaders, athletes, and celebrities Chris Hemsworth, Kim Kardashian, and Tony Robbins. In this episode, we move beyond the hype of "anti-aging" to explore the hard science of Muse cells (Multilineage-differentiating Stress-Enduring cells). Dr. Khan breaks down how these unique cells differ from the "medicinal signaling cells" (MSCs) found in most clinics and how they act as a bridge to a future where tissue regeneration is standard care.(0:00) The "Repair Guys" & The Muse Difference Dr. Khan explains why traditional stem cells (MSCs) often disappoint and how Muse cells offer the "best of both worlds": safety and pluripotency.(2:19) Smart Cells: How They Find the Damage Understanding the "homing mechanism" that allows Muse cells to sense inflammation and instinctively travel to injured areas like the brain or heart.(3:11) Curing the Incurable: Diabetes & Alzheimer's The potential of the "cure triad"—stem cells, gene therapy, and FMT—to treat complex autoimmune diseases within the next decade.(4:40) Biological Noise & The Symphony of Health How "static" in our gene expression indicates aging, and how cellular therapy can reduce this noise to restore the body's harmony.(6:40) The Viral Monkey Study Dr. Khan discusses a recent study showing significant de-aging in monkeys through high-frequency cell dosing.(7:32) Unshakeable Foundations: Lifestyle as MedicineWhy advanced therapies must be paired with purpose, community, and mindfulness to create a "bulletproof" body.(8:44) From Sketchy to StandardizedNavigating the regulatory landscape: why Muse cells are being classified as a drug in regions like the UAE and the path toward FDA approval.(12:24) A Personal MissionDr. Khan shares the origin of his journey: trying to find solutions for his mother's chronic illness when traditional medicine failed.(14:16) The Cancer HunterUnlike other pluripotent cells that risk tumor growth, Muse cells have a unique mechanism that can detect cancer cells and trigger their death.(18:30)Future Outlook: AI, Nature & Blue Zones Reflections on the risks of AI, the importance of "Blue Zone" city design, and reconnecting with nature in a post-human world.Episode Websitewww.creativeprocess.info/podInstagram:@creativeprocesspodcast
"Mojo Mentor" Loz Antonenko. Loz shares her raw and unmasked journey of surviving a "trauma plot twist" that reads like a binge-worthy series. Over the last 20 years, she has spent over $600,000 on her health journey simply to stay alive.Key topics discussed in this episode:The Radical Truth: Loz details the reality of undergoing a $20,000 fecal microbiota transplant (FMT), which involved self-infusing frozen enemas for six months.The Biohacking Trap: Why Loz believes you cannot "out-hack" the unsexy basics of eating, breathing, sleeping, moving, and hydrating.The Survival Mindset: Navigating life while managing two active brain tumors and a history of chronic inflammatory conditions.Handbrake Habits: How high-performers can stop running on fumes by identifying the habits that are actually slowing them down.Neurodiversity: Embracing life as a "neuro-spicy" individual with unmasked ADHD.The Cost of Ambition: Why burnout is not a sign of ambition, but rather an "unpaid health debt".Loz challenges the "standard Australian diet" (SAD) and the system of "subsidized dependency," offering a pragmatic, science-based approach to reclaiming your joy and your health.Connect with Loz here:FB: https://www.facebook.com/LozAntonenkoIG: https://www.instagram.com/lozantonenko/X: https://x.com/lozantonenkoYouTube: https://www.youtube.com/lozlifeLinkedIn: https://www.linkedin.com/in/lozantonenko/
Singer-songwriter and Lyme disease advocate Jesse Ruben joins the Tick Boot Camp Podcast for an incredibly honest, emotional, and deeply educational conversation about chronic Lyme disease, identity loss, treatment failure, unconventional healing, relapse, nervous system trauma, and the role of music and community in survival. Jesse's journey spans more than a decade and includes misdiagnosis, years of antibiotic treatment, experimental therapies, remission, relapse during the pandemic, gut microbiome restoration, nervous system healing, and ultimately a renewed sense of purpose through advocacy and art. This episode is essential listening for anyone navigating chronic Lyme disease, supporting someone who is sick, or questioning whether healing is still possible. Jesse Ruben's Early Life and Music Career Jesse grew up outside Philadelphia, surrounded by music, creativity, and curiosity. While he jokes that his songwriting degree was “a very expensive, useless piece of paper,” the competitive creative environment of music school helped sharpen his storytelling voice. By his early 20s, Jesse was living in New York City, touring, running marathons, and building momentum as an independent musician. He had just completed his third New York City Marathon, was in peak physical condition, and his career was accelerating—until his health began to unravel. The Onset of Illness: When Lyme Disease Took Everything Jesse's first red flag appeared when he became short of breath climbing subway stairs, despite being a marathon runner. Soon after, nausea, dizziness, headaches, neurological symptoms, and crushing fatigue followed. On Christmas Day 2012, Jesse developed what seemed like a flu that never went away. Over the following months, symptoms escalated dramatically: Severe fatigue that made basic movement impossible Brain fog and memory loss Crawling sensations under the skin Air hunger and dizziness Anxiety, depression, and mood changes Weight loss and neurological dysfunction Despite seeing 15 doctors over nine months, Jesse received conflicting diagnoses ranging from vitamin deficiencies to fibromyalgia and lupus. Every test came back “normal.” Insurance denied coverage. Doctors told him he would “have to live with it.” During a national tour, Jesse was so debilitated that a friend physically lifted him onto the stage to perform, then carried him back to the van afterward. Eventually, through relentless self-research, Jesse discovered a symptom list online that finally connected the dots: Lyme disease. Diagnosis and Early Treatment Failure Jesse was ultimately diagnosed at the Morrison Center in New York City, where testing confirmed: Lyme disease Babesia Mycoplasma His initial treatment path included: 6 months of oral doxycycline 18 months of IV azithromycin Antiparasitics Mepron (for Babesia) Antifungals, antivirals, supplements, and Chinese herbs Despite years of treatment, nothing produced lasting improvement. Jesse describes his life during this period as being reduced to pill schedules, doctor visits, and survival mode. The Game Changer: Chelation and Ozone Therapy After nearly three years with minimal progress, Jesse's provider, Dr. Gerald (“Jerry”) T. Simons at the Morrison Center, suggested a more experimental approach: chelation combined with ozone therapy. Jesse underwent IV chelation and ozone therapy multiple times per week for several months. The results were dramatic. Nearly all of Jesse's symptoms resolved, and for the first time, he felt like himself again. Even years later, booster ozone treatments helped stop symptom flares before they escalated.
Hi gang!FMT is back again and we;re repeating ourselves in a really good way!This weeks episode is class for 3 reasons:1) STEAKY IS BACK, meaning it's the first full FMTeam line-up in AGES,2) Ledley Kings League is back, and3) tangents. So many tangents.Thisa week, the gang are drafting 5-a-side teams based on past and present Premier League players. Rich and Jeb are old hands at this, Dee and Steaky are LKLV's.Who did the best job? You decide! Vote in our twitter poll, let your voice be heard and your chosen winner crowned.It's good to be back.VIVA LA FMT!Our links:https://linktr.ee/fmtpodhttps://twitch.tv/richowensfmhttps://twitch.tv/jebaroohttps://twitch.tv/deeboiplayshttps://twitch.tv/the_steak_bakeCupburger: https://www.cupburger.org#FMT #FootballManager #Football #Soccer #FM26 #FM
Hi gang!HAPPY NEW YEAR!FMT are BACK for another instalment of dutty podcastin'.On this weeks eposide, the gang take a dive into the world of FM appropriate music. What song is Rich playing to fire his team up? What is Dee spinning when his side are down at half time? What's Jeb whacking on when his team win?We also see the return on the classic FMT community one save challenge - Yokohama FC aren't going to manage themselves...This weeks episode was inspired by our very own Sweet Dee's 26 in 26 song challenge WHERE HE'S RELEASING 26 SINGLES IN 2026 - the incredible first installment Avalance is avalible to stream NOW!Go listen to that, then this and then that again.In that order.VIVA LA FMT!Our links:https://linktr.ee/fmtpodhttps://twitch.tv/richowensfmhttps://twitch.tv/jebaroohttps://twitch.tv/deeboiplayshttps://twitch.tv/the_steak_bakeCupburger: https://www.cupburger.org#FMT #FootballManager #Football #Soccer #FM26 #FM
Faecal transplant, also known as faecal microbiota transplantation or FMT, is the transfer of stool from a healthy donor to a patient with a disease. The idea is to restore the balance of bacteria in the gut, which can be disrupted by factors such as antibiotics, diet, or infection but it could potentially help with a range of problems from irritable bowel syndrome to Alzheimer's. Why is faecal transplant used? How does faecal transplant work? How is faecal transplant performed? What are the risks of faecal transplant? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: Could Britain ever rejoin the EU? What 5 foods can improve brain performance? What is pandemic skip? A podcast written and realised by Joseph Chance. First broadcast: 10/8/2023 Learn more about your ad choices. Visit megaphone.fm/adchoices
You've heard it before- the gut plays an extremely important and vast role in our behavior and health. In today's episode, I, and my guest Melissa, dive even deeper into the importance of the gut microbiome and discuss FMT or Fecal Microbiota Transplants. That's right, take someone else's poo and shove it up your dog's booty to transfer all the good bugs into your pup's gut microbiome. Check out FMT products at 15% off here. Your discount is automatically applied at checkout.
The Perfect Stool Understanding and Healing the Gut Microbiome
Learn about Novel Biome's purified capsule and powdered FMT (fecal microbiota transplant) products, the donor screening process, why pretreatment and protocol design matter and what kinds of conditions respond best to FMT beyond C diff, including IBS, IBD, neurological disorders and cancer with Dr. Jason Klop. Jason also talks about the pitfalls of DIY FMT, what stool testing can and can't tell you and how microbiome banking could help people protect their gut health long-term. Lindsey Parsons, your host, helps clients solve gut issues and reverse autoimmune disease naturally. Take her quiz to see which stool or functional medicine test will help you find out what's wrong. She's a Certified Health Coach at High Desert Health in Tucson, Arizona. She coaches clients locally and nationwide. You can also follow Lindsey on Facebook, Tiktok, X, Instagram or Pinterest or reach her via email at lindsey@highdeserthealthcoaching.com to set up your free 30-minute Gut Healing Breakthrough Session. Show Notes
Show notes: (0:00) Intro (1:11) Mary's global travels and ancestral healing approach (2:18) Exploring microbes and FMT in Norway (3:14) Why "fun" is vital to healing (5:17) How dance restores the body and mind (7:27) Why many tribes don't get diseases (9:54) The healing power of sunlight (12:47) Mayan culture's built-in gratitude practice (14:37) Birth microbes and their role in immunity (17:00) The Chaga tribe's joyful, nutrient-rich lifestyle (19:57) How modern diets are failing and why (26:47) Safe carbohydrates depending on health issue (30:04) C-section births and rebuilding microbiomes (32:08) Determining which diet is for whom (34:21) The Quechua's diet and culture (38:41) Animal-based glyconutrients and healing soups (43:16) How "helping" can harm indigenous cultures (46:45) Rethinking charity and sustainable support (48:44) Where to find Mary and her work (49:43) Outro Who is Mary Ruddick? Mary Ruddick is a Human Ecologist and microbiome expert known for reviving the ancestral human microbiome. Part researcher, part explorer, she has traveled through deserts, jungles, highlands, Arctic regions, and even conflict zones to study the diets and microbial patterns of the world's last traditional cultures. Her work reveals how these untouched tribes maintain extraordinary health across generations without modern medicine. From scientific stages to remote ceremonial sites, Mary is sought after to explain why modern health is declining and how to restore what humans have lost. Her approach blends neurobiology with microbial science, using ancestral "birthright" microbes to rebuild resilience. Through her global practice, teachings, and 100+ podcast appearances, she guides people back to the original human blueprint—symbiotic, sovereign, and vibrantly alive. Connect with Mary: Website: https://www.maryruddick.com/ Minnect: https://app.minnect.com/expert/MaryRuddick Links and Resources: Peak Performance Life Peak Performance on Facebook Peak Performance on Instagram
Dr. Ihor Basko, a holistic veterinarian from Hawaii, discusses with Dr. Judy his approach to aging in pets, emphasizing the importance of nutrition and supplementation. He highlights the role of antioxidants, particularly CoQ10, in supporting heart, kidney, and brain health. He also recommends cruciferous vegetables, clover sprouts, and chlorella for detoxification. Dr. Basko is a huge fan of medicinal mushrooms like Reishi, Cordyceps, and Lion's Mane for overall health and cognitive support. Additionally, he stresses the benefits of massage and bathing for senior pets, aiming to improve circulation, mobility, and skin health. Lots to learn! Website: www.drbasko.com Social Media URLs Facebook: https://www.facebook.com/FreshFoodAncientWisdom https://www.facebook.com/drbasko https://www.facebook.com/ihorbasko/ PRODUCT SPOTLIGHT #1 13:37 At Treatibles. We understand that every pet is unique, so we offer a range of products to meet their specific needs, all packed with the same powerful five in one benefits for a balanced, healthy lifestyle, whether it's easing stress, supporting joints, boosting immunity, balancing digestion or bringing calm to the day. Treatibles products are designed with these five essential benefits in mind. For pets who prefer a crunchier option, our hard chewables are crafted to be both satisfying and beneficial. Our soft chewables provide all the same benefits in an easy to enjoy form that's easier on teeth for senior pets. If you're looking for flexibility, our oil droppers let you control the dosage with ease and for targeted relief. Our transdermal cream works directly on the skin, providing a soothing, direct application for aches and stresses, but can also be used for general purposes by applying to the tips of the ear. A healthy, happy pet means harmony for the whole family. Go to https://treatibles.com/ and use discount code DRJUDY40 for 40% off. PRODUCT SPOTLIGHT #2 You've heard me say it many times, gut health is the foundation of overall health for both dogs and cats, and sometimes probiotics and diet changes just aren't enough. That's where Legacy Biome comes in. Legacy Biome offers fecal microbiota transplant products, FMT for Dogs and cats. Made from carefully raised donors on clean, natural diets with no antibiotics, pesticides or chemicals. That means every product delivers a healthy, resilient microbiome that you can trust. What I love is that you can get Legacy Biome directly for your pet or through your veterinarian, either way, you're giving your pet the very best support for gut health. Visit legacybiome.com to learn more and see how FMT can help your dog or cat live a healthier, happier life.
Hi gang!FMT is BACK, baby! Weekly episodes are here again. What a time to be aliveRich is also back, but that's less exciting.On this weeks episode, there's more good and bad from that FM26 you've heard so much about, some Brighton Women's updates (j'adore Kiko Seike), agent sackings, unclickable X's and some good old fashioned football trivia.What's not to love?VIVA LA FMT!Our links:linktr.ee/fmtpod
I denne episoden møter jeg lege og allmennspesialist Frank Hilpüsch. Han er forsker og en av pionerene innen fekal mikrobiota transplantasjon, FMT, som behandling for blant annet irritabel tarm syndrom.Vi snakker om hvordan moderne livsstil, antibiotikabruk og miljøet rundt oss påvirker tarmfloraen, og hvorfor mikrobiomet kan være nøkkelen til alt fra bedre fordøyelse til psykisk helse og forebygging av nevrodegenerative sykdommer.Frank deler også hvordan kosthold spiller en viktig rolle for å bevare en sunn tarmflora, men forklarer hvorfor mange pasienter likevel ikke klarer å spise seg ut av mageproblemene sine. Du får høre hva FMT egentlig er, og hvorfor dette har svært god effekt hos mange pasienter. For mer fra Frank:Spesialist klinikkenVil du teste BookBeat? Nå får du 60 dager gratis. Gå inn på bookbeat.no og bruk koden legeromlivet i et ord, eller gå inn på bookbeat.no/legeromlivet.Tusen takk til ukens sponsor IF forsikring, if.no/kritisksykdom.Ønsker deg en nydelig uke!AnnetteFølg meg gjerne på:Instagram.com/dr.annettedraglandFacebook.com/drannettedraglandhttps://youtube.com/@drannetteDisclaimer: Innholdet i podcasten og på denne nettsiden er ikke ment å utgjøre eller være en erstatning for profesjonell medisinsk rådgivning, diagnose eller behandling. Søk alltid råd fra legen din eller annet kvalifisert helsepersonell hvis du har spørsmål angående en medisinsk tilstand. Hosted on Acast. See acast.com/privacy for more information.
On this weeks episode @thejebaroo & @deeboiplays go over everything that's happened in the last few days since the @footballmanager FM26 Advamced Early Access Beta dropped (does anyone know the actual name?!)In classic FMT fashion and with the thought of Kev judging us we've kept it as fair and balanced as we can by listing off our 3 GOOD things about FM26 and 3 BAD things about FM26 (spoilers there's at least 2 on the thumbnail)We also delve into how far we've got with our official Advanced Early Access Beta Preview Save at Brighton Womens in the WSL!VIVA LA FMT!Our links: https://linktr.ee/fmtpod
Dr. Sean O'Mara shares his mission to reverse chronic disease for humanity. Dr. O'Mara has worked with high-ranking government officials, elite performers, and everyday people, helping them optimise their health through natural lifestyle choices. He opens up about his own journey of reversing multiple chronic diseases, his groundbreaking researchon disease reversal in Americans, and what he's learned about the root causes of modern illness. We cover:
On this episode of Vitality Radio, Jared sits down with Dr. Jason Klop, founder of Novel Biome, to explore one of the most fascinating and misunderstood frontiers in health: fecal microbiota transplant (FMT). Often misnamed “fecal matter transplant,” FMT is a highly purified process that restores microbial diversity in the gut—far beyond what probiotics alone can achieve. Jared and Dr. Klop discuss why FMT is gaining traction in digestive health, neurological conditions, and immune balance, and how it differs from traditional probiotic supplementation. You'll learn about the rigorous donor screening process, oral vs. rectal delivery methods, and why gut microbiome diversity is critical for overall vitality. The potential applications of FMT are broad and promising. This conversation pulls back the curtain on how supporting the gut ecosystem could impact everything from digestion and inflammation to mood and longevity.Additional Information:Novel BiomeNovel Biome - InstagramPodcast – Biome Breakthroughs (Spotify): Listen hereVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
Send us a textWelcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining fecal microbiota transplantation (FMT) in primary C. difficile infection. Here we go!Fecal Microbiota Transplantation Versus Vancomycin for Primary Clostridioides difficile Infection: A Randomized Controlled Trial (0:00 – 4:47).The Good Stuff (4:48 – 5:36):The I'm Pharmacy podcast, now featured on https://medicinepods.com/im-pharmacy/.Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods
The cause of autism revealed—is it Tylenol? Is there an ideal probiotic for Crohn's Disease? Treating constipation by modifying the microbiome with botanicals; ACTION ALERT: If Congress has its way, 95% of natural hemp products with CBD/THC may be banned by year's end! The popular diet that reverses psoriasis; A daily habit that could save you from chronic back pain.
Fecal microbiota transplantation (FMT) is a therapy that restores balance in the gut by transferring healthy bacteria, helping patients escape the cycle of repeated antibiotic failures and infections A recent clinical trial found that FMT was safe and well tolerated in frail long-term care patients, showing fewer bloodstream infections and less antibiotic use than standard care Even though transplant recipients still carried resistant bacteria, they experienced fewer serious infections, proving that restoring microbiome diversity strengthens the body's defenses against harmful microbes A national registry of 259 patients showed 90% were cured of recurrent Clostridioides difficile (C. difficile) infection after just one FMT treatment, with results lasting beyond six months FDA-approved products like Vowst and Rebyota now make FMT accessible in oral capsule and rectal forms, offering new hope for those facing stubborn gut infections
Alternatives to surgery for venous insufficiency; AI “hallucinates” a never-before-seen brain region in crucial test; Vegetarian complains she is prone to falling; Could tinnitus be triggered by electromagnetic fields from lighting, devices? Cannabis derivatives improve sleep where drugs fail; A novel way of treating chronic nasal infections—with snot transplants! Mitochondrial dysfunction found to be the key to heart, brain problems.
Introduction In this solo episode, Darin dives into a practice that has been both revered and misunderstood across history: the enema. From ancient Egypt and Mayan rituals to Ayurveda and modern biohacking, enemas have long been used as tools for cleansing, hydration, and targeted healing. Darin shares his own two-decade experience with enemas — from parasite cleanses to coffee enemas — and explores the science, history, and red flags you need to know. This is not medical advice, but an invitation to learn from ancient wisdom and consider how these practices might support your own healing journey. What You'll Learn 00:21 – Why enemas have been used for thousands of years, from Egypt to the Maya 01:33 – Parasite cleansing, hydration, and creating an environment for balance 02:38 – Pharaohs' “shepherds of the king's rectum” and enemas in ancient medical texts 03:20 – Ayurveda protocols for cleansing, oils, and elimination support 04:25 – The Maya's ritual use of enemas, including psychoactive delivery 05:22 – Enemas as lifesaving hydration in medical history (Murphy's Drip) 06:30 – FDA-approved microbiome enemas and rapid constipation relief 07:24 – Parasite cleanses, detox protocols, and Darin's own experiences 08:38 – Why we all live with parasites and how enemas help restore balance 09:19 – Ancient wisdom vs. modern medicine: why we need both 10:19 – Coffee enemas, liver support, detox, and peristalsis stimulation 11:20 – Lights turning back on: Darin's personal benefits from enemas 12:20 – Red flags: who should not do enemas (IBD, bleeding, surgeries, etc.) 13:47 – The importance of fiber, microbiome support, and daily practices 15:21 – Why Darin does two enemas a week and how they “turn the lights back on” 16:32 – Closing reflections: enemas as ancient tools for hydration, cleansing, and microbiome health Thank You to Our Sponsors: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Our Place: Toxic-free, durable cookware that supports healthy cooking. Use code DARIN for 10% off at fromourplace.com. Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Website: https://superlife.com Book: Fatal Conveniences Key Takeaway “From the pharaohs to Ayurveda to modern biohacking, enemas have always been about accessing the body in powerful ways. Used with care and wisdom, they can reawaken ancient practices of cleansing, hydration, and healing.” Bibliography & Sources Egypt / Antiquity: Hektoen Int'l on the Shepherd of the Rectum; overview of Egyptian proctology terms. Encyclopedia Pub Ayurveda (Basti): Classical reviews and practitioner summaries of Nirūha/Anuvāsana, indications, and protocols. IJRAPCalifornia College of Ayurveda Maya ritual enemas: Carod-Artal review (2015) and De Smet et al. on ritual enemas/psychoactives; museum/archaeological overviews with ceramic scenes. ScienceDirect+1 Rectal rehydration / proctoclysis: Wilderness case report of successful rectal ORS in hemorrhagic shock; historical review of proctoclysis as standard therapy (late 19th–early 20th c.). SAGE JournalsPMC Constipation/impaction patient education: Cleveland Clinic guidance on when/how enemas are used. Cleveland Clinic Parasite obstruction (Ascaris): pediatric surgical series noting hypertonic saline enemas for colonic worm disentanglement; newer case discussions. Lippincott JournalsPMC Microbiome therapy (powerful modern rectal route): FDA approval docs and clinical literature for REBYOTA(enema) and FMT efficacy. U.S. Food and Drug AdministrationCleveland Clinic Journal of Medicine Risks & what to avoid: FDA safety communication on phosphate enemas; case report of coffee-enema proctocolitis; reviews cautioning routine “colon cleansing.” U.S. Food and Drug AdministrationPMC
The Perfect Stool Understanding and Healing the Gut Microbiome
What happens when a preventable infection takes the life of someone you love? In this episode, Christian John Lillis shares the heartbreaking story of losing his mom to C. difficile, a bacterial infection, and how that loss inspired his mission to fight back. He talks about what everyone needs to know about C. diff: the warning signs, how it spreads, the importance of early treatment and steps we can all take to prevent it becoming more serious. This is more than a story of loss—it's a call to action for awareness, advocacy and protecting our loved ones. Lindsey Parsons, your host, helps clients solve gut issues and reverse autoimmune disease naturally. Take her quiz to see which stool or functional medicine test will help you find out what's wrong. She's a Certified Health Coach at High Desert Health in Tucson, Arizona. She coaches clients locally and nationwide. You can also follow Lindsey on Facebook, Tiktok, X, Instagram or Pinterest or reach her via email at lindsey@highdeserthealthcoaching.com to set up your free 30-minute Gut Healing Breakthrough Session. Show Notes
In this VETgirl online veterinary continuing education podcast, we chat with Jenessa A. Winston, DVM, PhD, DACVIM (SAIM), Associate Professor of Small Animal Medicine at the Ohio State University about the importance of microbiome for and beyond, gut health. What is the microbiome, and what type of gastrointestinal (GI) microorganisms are we talking about? How does GI microbiome apply to us in clinical daily practice? What role does the GI microbiome play with acute hemorrhagic diarrheal syndrome to chronic enteropathy to parvovirus, and does fecal microbiota transplantation (FMT) help too? Tune in to learn about how you can support microbiome and the whole patient's health!Sponsored By: Hills
In this VETgirl online veterinary continuing education podcast, we chat with Jenessa A. Winston, DVM, PhD, DACVIM (SAIM), Associate Professor of Small Animal Medicine at the Ohio State University about the importance of microbiome for and beyond, gut health. What is the microbiome, and what type of gastrointestinal (GI) microorganisms are we talking about? How does GI microbiome apply to us in clinical daily practice? What role does the GI microbiome play with acute hemorrhagic diarrheal syndrome to chronic enteropathy to parvovirus, and does fecal microbiota transplantation (FMT) help too? Tune in to learn about how you can support microbiome and the whole patient's health!Sponsored By: Hills
Dr. Sumanta (Monty) Pal and Dr. Arielle Elkrief discuss the clinical relevance of the gut microbiome in cancer immunotherapy and the importance of antibiotic stewardship, as well as interventions currently being explored to treat gut dysbiosis and optimize immunotherapy response. TRANSCRIPT Dr. Sumanta (Monty) Pal: Hi everyone, I'm Dr. Monty Pal, welcoming you to the ASCO Daily News Podcast. I'm a medical oncologist. I'm a professor and vice chair of academic affairs at the City of Hope Comprehensive Cancer Center in Los Angeles. Today we're here to discuss one of my favorite topics, which is the gut microbiome. It's almost hard to avoid the gut microbiome nowadays if you look at medical literature within oncology. It's an emerging phenomenon, but there are a couple of individuals that I would really define as pioneers in the field. And one of them is actually with me today, Dr. Arielle Elkrief, to discuss the clinical relevance of the gut microbiome, particularly amongst patients receiving immunotherapy, although I imagine our conversation today will take many twists and turns. Arielle is an assistant professor and clinician scientist in the Department of Oncology at the University of Montreal, and she is co-director of the CHUM Microbiome Center there. FYI for the listeners, we have our full disclosures in the transcript of this episode. Arielle, thank you so much for joining us today. Dr. Arielle Elkrief: Thanks so much, Monty. This is going to be amazing. Dr. Sumanta (Monty) Pal: Well, I have to tell you what sort of inspired me to bring you on as a guest. It was one of many things, but it was this really terrific ASCO Educational [Book] article that you wrote. Now, I have to tell you, I've read all the articles sort of cover to cover in the book, and they're always a wonderful primer, so if our audience is studying for board research or something of that sort, it's a terrific resource to go through. I have to tell you, this piece on the gut microbiome that you wrote is nothing short of a masterpiece. If you read this cover to cover, it's actually going to give you, I think, a sense of the current state and future state of the field. I wanted to start by just sort of beginning with sort of the origin story for a lot of this, which is this association between the gut microbiome and immunotherapy response. This takes us back several years to this pivotal series of papers in Science. Maybe you could walk our audience through that. Dr. Arielle Elkrief: Absolutely. Well, thank you so much for your kind words about the ASCO [Educational] Book. It was a team effort with a lot of key opinion leaders in the field, so I'm really glad to learn that you've liked it. Moving backwards in terms of how we came to understand that the gut microbiome is essential to priming a response to cancer immunotherapy actually goes back to 2015 and seminal papers that looked at what happens when we take mice that are germ-free mice that have never been exposed to a microbiome. These are mice that are born by cesarean section and essentially live in a bubble. And when we give those mice tumors and treat them, in the first papers with anti-CTLA-4 treatment, we realized that these antibodies don't work at all. And that was the first observation that the presence of a gut microbiome was essential to mounting an anti-cancer immune response. When we supplemented those same mice with beneficial bacteria or feces from responder patients, we were able to restore the response to immunotherapy. And so those were really the first preclinical observations that made us understand the critical role of the microbiome in immunotherapy response. Moving a little bit in the future, we examined the fecal microbiome composition using shotgun metagenomic sequencing in different cohorts of patients with solid tumors, namely lung cancers, kidney cancers, and also skin tumors like melanoma, and found that patients who responded to immunotherapy had a distinct microbiome that was characterized by beneficial bacteria compared to patients who experienced resistance to immunotherapy that had a dysbiotic or diseased microbiome. Dr. Sumanta (Monty) Pal: So, you know, it's interesting, these techniques that we're using to sequence the gut, they're a little bit different. So I wonder if you can give the audience a quick primer on these techniques that you're so well versed in, shotgun metagenomic sequencing, 16S rRNA sequencing. If you had to describe this in 30 seconds, which is a tall task, how would you do that? Dr. Arielle Elkrief: That's a tall task. Much of what we know about the microbiome initially came from a technique called 16S rRNA sequencing. This is a technique that amplifies the 16S region and basically tells you at the genus level what's going on at the level of bacterial composition. This technique is fast, relatively cheap, and can be performed on a laptop computer, which is excellent. The problem is that it's prone to a lot of technical variations. Different primers might give you different results, and you're really limited at the genus resolution. You can't get a good resolution in terms of species, and we're learning that different species from the same genus might have different physiological properties, and the same thing goes at the strain level. So when we really zone in and look at inter-species changes, we're seeing that these actually have specific functions in the host. So that brings us to metagenomic sequencing, which is a whole genome sequencing, next-generation sequencing based method that looks at the whole composition and gives you information not only on bacteria, but you might also get fungal and viral properties. You can zoom in on the strain level. You can also get functional output, so we can examine what the metabolic properties of specific species or strains might look like. The negative aspects of shotgun metagenomic sequencing is that it takes a lot of computational power in order to analyze the results and it might take a little bit longer. And certainly, within the clinical setting, not something that's feasible yet. And that brings us to more novel point-of-care biomarker tools that we've collaborated in developing along with Dr. Laurence Zitvogel and Dr. Lisa Derosa at Gustave Roussy, that learning from the shotgun metagenomics results designed a probe using quantitative PCR which looks for this specific bacteria we know to be important and developed a ratio of harmful bacteria to beneficial bacteria. This is called the TOPOSCORE, and it actually is able to predict quite nicely the response to immunotherapy using a stool sample and a really good turnaround time of almost 72 hours. Dr. Sumanta (Monty) Pal: That was a perfect overview and a lot of information in a short amount of time. It also makes you take out your high school biology textbooks, doesn't it, to understand that the bacterial ribosome, right, is a different size and shape, and that's what we're sequencing here. But these techniques I think are incredibly important, and I'm glad you actually discussed this, this RT-PCR based strategy of calculating the TOPOSCORE. It lends itself to this phenomenon of dysbiosis, and I think for our audience, that's going to be an important term to understand as time goes on. There's the normal healthy gut and then there's this phenomenon of dysbiosis, which is, I guess, simply put, an unhealthy gut. But tell us about, you know, how often you see dysbiosis in a cancer patient, maybe versus a normal healthy adult. Dr. Arielle Elkrief: So, I think we can split up your question into two parts. One is we know from cohort studies and population level-based studies that the microbiome of patients with cancer is distinct from healthy patients or healthy people. And we know that because of the global composition. We also think that there are diversity metrics that lend themselves to being described as dysbiotic. But we do know that the microbiome of people with cancer is distinct from healthy volunteers. That's the first point. In terms of how frequently dysbiosis occurs in patients with cancer, it's not very well defined. We know that even among healthy people, there is a certain level of dysbiosis. Laurence in her talk mentioned that to be about 10% to 20%. And the other fascinating component is that when we're thinking about dysbiosis and the cancer associated microbiome, in terms of the species that are enriched, it's quite striking that a lot of these dysbiotic or negative bacteria are also found to be enriched in patients with metabolic disease, like cardiovascular disease, for example. And so it's unclear if dysbiosis is the cause or consequence, but there definitely seems to be a general pattern of disease when looking at the microbiome compared to healthy people. Dr. Sumanta (Monty) Pal: That's interesting. So, I'll tell you, my second favorite portion of your article, and I'll tell you my favorite portion as well in the context of this podcast, but my second favorite part was the section around antibiotic stewardship. You know, the utilization of antibiotics in a very pragmatic fashion amongst our patients. Can you describe why that's so critical in the context of the microbiome? Dr. Arielle Elkrief: Antibiotics can disrupt the gut microbiome composition. We know this from mouse studies, but also cohort studies of patients that are exposed to antibiotics. And most importantly, we know that patients who are exposed to antibiotics, either before or during the immunotherapy period, have significantly worse progression-free survival and overall survival to immunotherapy. And this is true for immunotherapy in the monotherapy setting, but also when combined with chemotherapy. What's striking is that when we look at patients who are just treated with chemotherapy, we don't see the negative outcome of antibiotics on outcome and progression-free survival and overall survival, suggesting that the negative impact of antibiotics on outcomes is really specific to immunotherapy backbones. The other important point is that this negative signal is maintained even after adjusting for standard prognostic variables in the specific malignancies that we're looking at. And then most importantly, at the mechanistic level, we were able to actually pinpoint the mechanism behind this antibiotic related dysbiosis. And we see this with a bloom of negative bacteria which induces a loss of MAd-CAM, which is an endothelial gut checkpoint immune marker, and that causes an efflux of immunosuppressive T cells, which are usually in the gut, to go straight into the tumor where they make the tumor unamenable to an immunotherapy response. And so now we finally have the mechanism as to why antibiotics are harmful and why we need to practice antibiotic stewardship. Dr. Sumanta (Monty) Pal: And just to be clear for the audience, I mean, if a patient needs antibiotics, they need antibiotics. But perhaps it just suggests that, and we have, I suppose, this predilection as oncologists, just for the minor cold or cough or what have you, we maybe should be a little bit more cognizant of whether or not antibiotics are truly necessary. Is that fair? Dr. Arielle Elkrief: Absolutely. So what we're advocating for is antibiotic stewardship, and this is the clear recommendation that we can make. So that means confirming a bacterial infection. If it's there and antibiotics are indicated, to choose the most narrow spectrum for the shortest course and constantly re-evaluate the indication of antibiotics. And of course, we need to work with our colleagues in infectious diseases who've done incredible work in antibiotic stewardship. And all along this process we also need to be mindful of other medications and polypharmacy, such as proton pump inhibitors or narcotics, for example, we think that these other medications which are frequently prescribed in our cancer population can also potentially have negative impacts on the microbiome and immunotherapy response. Dr. Sumanta (Monty) Pal: I think that's a terrific summary and big guidance for the audience. I promised you I'd tell you my favorite part of your article, and this is this huge table. I think the table is two and a half pages long, if I remember correctly, but it's an awesome table, and I highly recommend our audience to check this out. It lists literally every therapeutic trial for the microbiome under the sun. And so it begins with the approach of fecal microbiota transplant, which I'm going to ask you to tell us about in a second, but it also hinges on a lot of really cool sort of novel therapies, live bacterial products, mixes of different microbial products. Maybe take us through this whole approach of FMT (fecal microbiota transplantation). I actually wasn't aware of the dozens of trials that you listed there in this space. It seems like it's a very active area of research. Dr. Arielle Elkrief: Definitely. So, as you alluded to, FMT or fecal microbiota transplantation is the most well studied and direct way to modify the patient's microbiome. This technique aims to replace the patient's dysbiotic microbiome with that of a healthy microbiome, either from a healthy donor volunteer that's been heavily screened, or from a patient who experienced response to immunotherapy. And, as three landmark studies so far that have been published demonstrated the potential of FMT to reduce primary resistance or secondary resistance to immunotherapy, and this has been in melanoma. We also recently reported on the results of our FMT-LUMINate trial, which looked at patients with lung cancer and melanoma. Once again, FMT, when combined with immunotherapy was safe and led to a higher proportion of responses than we would normally expect. We're now also looking at randomized trials that have come out. So the first being the TACITO trial in kidney cancer, which compared FMT plus pembrolizumab and axitinib to placebo in patients with RCC, and again, FMT was safe and feasible and also led to an increased progression-free survival at one year, meeting the study's primary endpoint. And so, so far, there's a wealth of data really showing the promise of FMT when combined with immunotherapy, and we're now in the process of conducting larger randomized trials, including in melanoma with the CCTG (Canada Cancer Trials Group) in our ME17 or Canbiome2 trial, where we're going to be enrolling 128 patients with metastatic melanoma to receive FMT and standard of care immunotherapy compared to standard of care immunotherapy alone. Dr. Sumanta (Monty) Pal: You're very humble, so I've got to highlight for our audience. This was a mega grant that Arielle received to fund really the largest prospective exploration of FMT that will exist to date. So I'm really excited about that. I wish this was something we could participate in stateside. Before we jump into the other approach, which is live bacterial products and mixes thereof, where do you see FMT going? I think that one of the perceived challenges with FMT is that it's hard to implement, right? You need to have a really robust framework when it comes to gastroenterology, the preparation's challenging. Is there a way to envision FMT use being more generalized? Dr. Arielle Elkrief: Those are great questions. So we're lucky in Canada to work with pioneers in FMT, Michael Silverman, Saman Maleki, and John Lenehan in London, Ontario, who had this really robust FMT healthy donor screening program, which literally screens for every pathogen under the sun, and we haven't had any problems with feasibility or implementing FMT in Canada. But I think that once we're going to hopefully start doing larger scale, randomized phase three studies, that we might run into problems with scalability. And I think also with regards to reproducibility, and that's the feedback that we're getting from some regulatory authorities, especially at the level of the FDA, where there are some concerns around inter- and intra-donor variability because, of course, we can't guarantee that every fecal sample is going to be the same. So that has really pushed the field to think about other strategies, such as live biotherapeutic products which take modified FMT or bacteria from stools from either healthy donors or from responder patients and basically turn them into drugs that are regulated as drugs and can then be studied in the context of investigational new drugs or products. Dr. Sumanta (Monty) Pal: I like this and, you know, I do think that there's a future for it. We just have to kind of put our heads together and figure out how to get over all of these logistical hurdles, but, you know, I agree, I think your group and others have demonstrated, especially with this trial that you're fanning out all throughout Canada, that it can potentially be done. This is a topic that could probably go on for another couple of hours, right, especially based on the size of the table that you put together in this brilliant article, but tell us about live bacterial products or LBPs, as we call them these days. What's the current status, what's the future there? And maybe I'll give you less than two minutes here, although again, I realize it's a two-hour topic. Dr. Arielle Elkrief: You're probably better suited to speak about that because you've been one of the pioneers in terms of this. So we can think about LBPs in terms of single strain organisms, like CBM588 for an example, which your group did some amazing work in showing that, in a randomized setting, that this led to better responses than we would expect compared to just work with controls. We also know that LBPs can have multiple strains, up to 30. We're collaborating with a company called Cannabis Bioscience that is actually working on much larger communities of consortia. And so we're really excited about the direction that that's taking in terms of taking these LBPs and developing them from the drug perspective. In addition to LBPs, we know that there are other ways that we can change the microbiome, notably prebiotics, which are compounds which can have a beneficial impact on the microbiome. And one of these is camu camu, which I know your group is leading a clinical trial looking at camu camu and kidney cancer, and we're excited to see how that compares to FMT or LBPs, because that might be a potentially scalable alternative. Dr. Sumanta (Monty) Pal: That's awesome. What a terrific overview, and that was less than two minutes. I don't know how you did it. That's terrific. Arielle, this has been such an insightful conversation. I just want to thank you for, again, a terrific article in the ASCO Educational Book. I highly recommend all of our listeners to go there and check it out, and also for sharing all these terrific insights on the podcast today. Dr. Arielle Elkrief: Thank you so much, Monty. Dr. Sumanta (Monty) Pal: And thanks to our listeners, too. If you value the insights that you heard today on the ASCO Daily News Podcast, please rate, review, and subscribe wherever you get your podcasts. Thanks, everyone. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Find out more about today's speakers: Dr. Sumanta (Monty) Pal @montypal Dr. Arielle Elkrief Follow ASCO on social media: @ASCO on Twitter ASCO on Bluesky ASCO on Facebook ASCO on LinkedIn Disclosures: Dr. Sumanta (Monty) Pal: Speakers' Bureau: MJH Life Sciences, IntrisiQ, Peerview Research Funding (Inst.): Exelixis, Merck, Osel, Genentech, Crispr Therapeutics, Adicet Bio, ArsenalBio, Xencor, Miyarsian Pharmaceutical Travel, Accommodations, Expenses: Crispr Therapeutics, Ipsen, Exelixis Dr. Arielle Elkrief: Honoraria: AstraZenica, Bristol-Myers Squibb, Merck, EMD Serono Consulting or Advisory Role: Bristol-Myers Squibb Research Funding (Inst.): Kanvas Bioscience, AstraZeneca, Merck Other Relationship: Royal College of Surgeons and Physicians of Canada, Cedar's Cancer Center (Henry R. Shibata Fellowship), Canadian Institutes of Health Research (CIHR)
In this episode of the Ageless Future podcast, host Cade Archibald dives deep into the gut-brain connection and how detoxing the digestive system can revitalize the immune system, boost energy, and improve mental clarity. Cade explains how gut imbalances, toxin overload, and vagus nerve dysfunction can lead to chronic fatigue, inflammation, neurodegeneration, and other health challenges. He shares practical strategies such as targeted peptides, mitochondrial support, and anti-inflammatory nutrition, along with a four-week gut-brain detox action plan to heal the gut lining, restore microbial balance, and optimize detox pathways. Listeners also learn about advanced treatments like umbilical cord plasma therapy and fecal microbiota transplants, as well as simple daily habits to strengthen the gut-brain axis for long-term vitality. www.agelessfuture.com
Dominate C. diff! Learn to distinguish colonization from infection, select first-line therapies, and counsel patients on recurrence prevention and microbiome recovery. We're joined by IDSA past president and expert on foodborne and intestinal infections, Dr. Cindy Sears (Johns Hopkins University) for a comprehensive update on Clostridioides difficile (C. diff, Cdiff, CDAD, CDI). Claim CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Show Segments 00:00 Intro 03:00 Guest bio and hobby 04:25 Case of Charles Fleur Fontaine 06:00 Risk factors and epidemiology 08:00 Antibiotic hierarchy of risk 10:00 Diagnosis, testing strategies 14:00 Defining severity 17:30 Treatment options 20:00 Microbiome recovery strategies 24:00 Probiotics and postbiotics 27:00 Infection control counseling 30:00 C. diff and colon cancer 32:00 Recurrent C. diff strategies 35:00 Why some FMT and bezlotoxumab were discontinued 38:00 Microbiota replacement therapies 43:00 Prophylaxis strategies 45:00 Future therapies and ongoing research 47:00 Audience Q&A 52:00 Outro Credits Written and Produced by: Matthew Watto, MD, FACP Cover Art and Infographic by: Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP Reviewer: Sai S Achi MD,MBA,FACP Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Cynthia Sears MD Disclosures Dr. Sears reports no relevant financial disclosures. Dr. Williams financial relationships disclosed include a Merck grant or research support. This relationship has not ended. Sponsor: Mint Mobile This year, skip breaking a sweat AND breaking the bank. Get this new customer offer and your 3-month Unlimited wireless plan for just 15 bucks a month at mintmobile.com/CURB Sponsor: Panacea Financial Let Panacea Financial take the financial stress off your plate,so you can get back to doing what matters most. Visit panaceafinancial.com Sponsor: FIGS Get15% off your first order at wearfigs.com with the code FIGSRX
#300 Today's guest is Dr. Andrea McBeth, a trailblazer in the world of microbiome therapeutics and the founder and CEO of Thaena — a company pioneering human-derived postbiotic solutions to support gut and whole-body health. Andrea holds a Bachelor's in Biochemistry with a focus on molecular biology from the University of San Diego, and earned her Doctorate in Naturopathic Medicine from the National University of Natural Medicine. Her early clinical work focused on functional GI disorders and autoimmunity, and she went on to launch one of the first stool banks for fecal microbiota transplantation to treat Clostridioides difficile infections. She's served as President of GastroANP and as adjunct faculty at NUNM, where she developed and taught graduate courses on the microbiome's role in nutrition. Passionate about bridging science and real-world healing, Andrea invented ThaenaBiotic, the first human-derived postbiotic supplement — and now leads the charge at Thaena to bring safe, scalable microbiome-based treatments to the world. In this episode, we explore: What regenerative health means in the context of human biology Why the microbiome is central to regeneration — and what a truly resilient gut ecosystem looks like How the microbiome supports repair and renewal throughout the body — from gut lining to immunity and even mood Which microbial species and metabolites stand out for their regenerative potential Daily habits and exposures that best nourish the microbiome and enhance its regenerative power Common lifestyle and environmental disruptors that undermine microbial diversity and function Whether the traditional health model focuses too heavily on eradicating pathogens (e.g., antibiotics, cleanses) instead of cultivating regeneration How Thaena is flipping the script through their unique product philosophy You'll also hear from Dr. McBeth about the innovative postbiotics she's developed — including how Thaena sources and processes human-derived microbiome metabolites, what makes them safe, and how they differ from prebiotics, probiotics, and even FMT “crapsules.” And so much more.
Dr. Sabine Hazen is a Gastroenterologist, Researcher, & CEO of Progena Biome. In this episode, she explains how fecal microbiota transplants (FMT) have the potential to treat Alzheimer's, Autism, Crohn's, Anxiety, Depression & Alopecia. She explains how it works, why mapping the microbiome is like mapping the human genome & interesting cases of personality changes post transplant. If you like this episode, you'll also like episode 188: BIOHACKING FOR DUMMIES: SUNSHINE, SLEEP & SHIVERS Guest: https://sabinehazanmd.com/ | https://x.com/SabinehazanMD | https://www.facebook.com/DoctorSabineHazan | https://www.instagram.com/dr.sabinehazan/ | https://www.linkedin.com/in/sabine-hazan-steinberg-md-5343b241/ | https://biomeboosters.com/ | https://progenabiome.com/ Host: https://www.meredithforreal.com/ | https://www.instagram.com/meredithforreal/ | meredith@meredithforreal.com | https://www.youtube.com/meredithforreal | https://www.facebook.com/meredithforrealthecuriousintrovert Sponsors: https://www.jordanharbinger.com/starterpacks/ | https://uwf.edu/university-advancement/departments/historic-trust/
Fecal transplants are an emerging new medical therapy that has been show to CURE cancer, Parkinson's, depression and anxiety, fibromyalgia, colitis and many more diseases both inside and outside of the gut. But this incredible (and kind of gross) procedure is taking the world by storm. It turns out that transplanting a healthy gut microbiome from one person to another can radically change their entire body, metabolism and even their personality. TOPICS DISCUSSED: What fecal transplants are and how they work Diseases they can cure or mediate and why they're so effective How these came about (with some funchistory facts) Why they're so effective and how they work to alter your biology The benefits of FMT and how much it costs Safety vs efficacy The potential doors this unlocks in the future Leave us a Review: https://www.reversablepod.com/review Need help with your gut? Visit my website gutsolution.ca to join a program: Get help now Contact us: reversablepod.com/tips FIND ME ON SOCIAL MEDIA: Instagram Facebook YouTube Watch the Designer $hit documentary: Website: designershitdocumentary.com Watch the film: Buy or Rent Studies on risks of FMT: PMC4986962
Fan Favorite: This episode originally aired on July 8, 2021. It's easy to quietly go through life never really facing yourself, your struggles and your fears. There is a solution to numb the pain of reality and move towards comfort where it's easier to accept things as they are no matter where you are. Mikhaila Peterson gracefully embodies the struggle of what it means to face yourself and all of your inadequacies and continue to push and explore through discomfort in pursuit of finding meaning while protecting what it means to be human, be a mother, be sexy and a successful business woman. SHOW NOTES: Accidental | Mikhaila talks about unplanned pregnancy at 23, career, & marriage [2:03] Anxiety & Chaos| Navigating stress from relationships and reducing chaos [7:17] Marriage | Mikhaila on the challenges of marriage before building foundation [10:12] Having Children | Is there a “right” time to have kids or only trade-offs to consider [14:54] Parenting Balance | How to balance an ambitious career and guilt free mothering [18:15] Criticism | Mikhaila on identifying where she could be wrong & being even keeled [25:28] Volatility | Mikhaila on how she's navigating her triggers and stress response [28:32] Self-Awareness | How Mikhaila began to notice her symptoms and reactions [33:18] Sex Appeal | Mikhaila on embracing her sex appeal and growing her business [38:12] Confidence | Having confidence & the borderline of being overly self conscious [51:12] Being Hardcore | What it takes to push self-limits and see what you can achieve [56:18] Having Impact | Mikhaila on getting “greedy” wanting to help many people [1:01:39] Pushing Limits | Finding balance to push too hard or being more reasonable [1:04:34] Burnout | Mikhaila on pushing through work you don't enjoy doing, outsourcing [1:10:18] Order & Chaos | Mikhaila on the navigating the balance of order and chaos [1:16:55] Discomfort | How to explore discomfort while building a brand vs. individual [1:19:46] Healthy Diets | Mikhaila on how she regulates diet chooses for her daughter [1:23:33] Carnivore Diet | Mikhaila on the benefits of an all beef diet on her body [1:29:00] FMT Experience | Mikhaila shares her experience with 10 FMT transplants [1:32:43] CHECK OUT OUR SPONSORS Vital Proteins: Get 20% off by going to https://www.vitalproteins.com and entering promo code IMPACT at check out Monarch Money: Use code THEORY at https://monarchmoney.com for 50% off your first year! Shopify: Sign up for your one-dollar-per-month trial period at https://shopify.com/impact Netsuite: Download the CFO's Guide to AI and Machine Learning at https://NetSuite.com/THEORY iTrust Capital: Use code IMPACTGO when you sign up and fund your account to get a $100 bonus at https://www.itrustcapital.com/tombilyeu Mint Mobile: If you like your money, Mint Mobile is for you. Shop plans at https://mintmobile.com/impact. DISCLAIMER: Upfront payment of $45 for 3-month 5 gigabyte plan required (equivalent to $15/mo.). New customer offer for first 3 months only, then full-price plan options available. Taxes & fees extra. See MINT MOBILE for details. ********************************************************************** LISTEN TO IMPACT THEORY AD FREE + BONUS EPISODES on APPLE PODCASTS: apple.co/impacttheory ********************************************************************** FOLLOW TOM: Instagram: https://www.instagram.com/tombilyeu/ Tik Tok: https://www.tiktok.com/@tombilyeu?lang=en Twitter: https://twitter.com/tombilyeu YouTube: https://www.youtube.com/@TomBilyeu Learn more about your ad choices. Visit megaphone.fm/adchoices
Fan Favorite: This episode originally aired on July 8, 2021. It's easy to quietly go through life never really facing yourself, your struggles and your fears. There is a solution to numb the pain of reality and move towards comfort where it's easier to accept things as they are no matter where you are. Mikhaila Peterson gracefully embodies the struggle of what it means to face yourself and all of your inadequacies and continue to push and explore through discomfort in pursuit of finding meaning while protecting what it means to be human, be a mother, be sexy and a successful business woman. SHOW NOTES: Accidental | Mikhaila talks about unplanned pregnancy at 23, career, & marriage [2:03] Anxiety & Chaos| Navigating stress from relationships and reducing chaos [7:17] Marriage | Mikhaila on the challenges of marriage before building foundation [10:12] Having Children | Is there a “right” time to have kids or only trade-offs to consider [14:54] Parenting Balance | How to balance an ambitious career and guilt free mothering [18:15] Criticism | Mikhaila on identifying where she could be wrong & being even keeled [25:28] Volatility | Mikhaila on how she's navigating her triggers and stress response [28:32] Self-Awareness | How Mikhaila began to notice her symptoms and reactions [33:18] Sex Appeal | Mikhaila on embracing her sex appeal and growing her business [38:12] Confidence | Having confidence & the borderline of being overly self conscious [51:12] Being Hardcore | What it takes to push self-limits and see what you can achieve [56:18] Having Impact | Mikhaila on getting “greedy” wanting to help many people [1:01:39] Pushing Limits | Finding balance to push too hard or being more reasonable [1:04:34] Burnout | Mikhaila on pushing through work you don't enjoy doing, outsourcing [1:10:18] Order & Chaos | Mikhaila on the navigating the balance of order and chaos [1:16:55] Discomfort | How to explore discomfort while building a brand vs. individual [1:19:46] Healthy Diets | Mikhaila on how she regulates diet chooses for her daughter [1:23:33] Carnivore Diet | Mikhaila on the benefits of an all beef diet on her body [1:29:00] FMT Experience | Mikhaila shares her experience with 10 FMT transplants [1:32:43] CHECK OUT OUR SPONSORS Vital Proteins: Get 20% off by going to https://www.vitalproteins.com and entering promo code IMPACT at check out Monarch Money: Use code THEORY at https://monarchmoney.com for 50% off your first year! Shopify: Sign up for your one-dollar-per-month trial period at https://shopify.com/impact Netsuite: Download the CFO's Guide to AI and Machine Learning at https://NetSuite.com/THEORY iTrust Capital: Use code IMPACTGO when you sign up and fund your account to get a $100 bonus at https://www.itrustcapital.com/tombilyeu Mint Mobile: If you like your money, Mint Mobile is for you. Shop plans at https://mintmobile.com/impact. DISCLAIMER: Upfront payment of $45 for 3-month 5 gigabyte plan required (equivalent to $15/mo.). New customer offer for first 3 months only, then full-price plan options available. Taxes & fees extra. See MINT MOBILE for details. ********************************************************************** LISTEN TO IMPACT THEORY AD FREE + BONUS EPISODES on APPLE PODCASTS: apple.co/impacttheory ********************************************************************** FOLLOW TOM: Instagram: https://www.instagram.com/tombilyeu/ Tik Tok: https://www.tiktok.com/@tombilyeu?lang=en Twitter: https://twitter.com/tombilyeu YouTube: https://www.youtube.com/@TomBilyeu Learn more about your ad choices. Visit megaphone.fm/adchoicesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Support your health journey with our private practice! Explore comprehensive lab testing, functional assessments, and expert guidance for your wellness journey. Find exclusive offers for podcast listeners at nutritionwithjudy.com/podcast. _____Dr. Neil and I dive into the complexity of the gut microbiome, challenging the notion that a single probiotic strain can fix everything. We explore how diversity—not one 'superbug'—may be the real key to gut health. We also unpack how fecal transplants work, why antibiotics often do more harm than good, and if fermented foods are necessary or ideal.Dr. Neil Stollman is a practicing gastroenterologist based in Oakland, California, and serves as voluntary faculty at UCSF. A pioneer in the field of fecal microbiota transplantation (FMT), he has been involved in gut microbiome research and treatment for over two decades. Known for his work with Clostridium difficile infection (CDI) and broader gut health issues, Dr. Stollman brings a balanced and often humorous perspective to microbiome science.We discuss the following:All about Dr. Neil StollmanThe importance of gut healthAll about AkkermansiaGlyphosate and other antimicrobial foodsFMT (Fecal Microbiota Transplantation)Getting sick from C. diff (Clostridioides difficile)Strengthening the MicrobiomeDo we need FermentsThoughts on giving antibiotics to people with C. diffSymptoms of H. pyloriThoughts on long-term PPI useWhy gut doctors prescribe PPIsThoughts on colon testsWhere to find Dr. Neil Stollman_____EPISODE RESOURCESWebsiteTwitterThe Sonnenburgs Fermented Food StudyOpenBiome (Stool Bank)NwJ Complete Wellness PanelComplete GI Map Stool Test_____WEEKLY NEWSLETTER
“Fecal microbial transplants” treat someone's unhealthy gut with poop from someone else's healthy gut, and proponents of FMT claim it can help treat everything from IBS to autism. But if your doctor isn't ready to fill you up with someone else's poop, the internet will happily oblige. Guest: Luke Winkie, Slate staff writer who published “The Poop Broker.”Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.Disclosure in Podcast Description: A Bond Account is a self-directed brokerage account with Public Investing, member FINRA/SIPC. Deposits into this account are used to purchase 10 investment-grade and high-yield bonds. As of 9/26/24, the average, annualized yield to worst (YTW) across the Bond Account is greater than 6%. A bond's yield is a function of its market price, which can fluctuate; therefore, a bond's YTW is not “locked in” until the bond is purchased, and your yield at time of purchase may be different from the yield shown here. The “locked in” YTW is not guaranteed; you may receive less than the YTW of the bonds in the Bond Account if you sell any of the bonds before maturity or if the issuer defaults on the bond. Public Investing charges a markup on each bond trade. See our Fee Schedule. Bond Accounts are not recommendations of individual bonds or default allocations. The bonds in the Bond Account have not been selected based on your needs or risk profile. See https://public.com/disclosures/bond-account to learn more. Hosted on Acast. See acast.com/privacy for more information.
“Fecal microbial transplants” treat someone's unhealthy gut with poop from someone else's healthy gut, and proponents of FMT claim it can help treat everything from IBS to autism. But if your doctor isn't ready to fill you up with someone else's poop, the internet will happily oblige. Guest: Luke Winkie, Slate staff writer who published “The Poop Broker.”Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.Disclosure in Podcast Description: A Bond Account is a self-directed brokerage account with Public Investing, member FINRA/SIPC. Deposits into this account are used to purchase 10 investment-grade and high-yield bonds. As of 9/26/24, the average, annualized yield to worst (YTW) across the Bond Account is greater than 6%. A bond's yield is a function of its market price, which can fluctuate; therefore, a bond's YTW is not “locked in” until the bond is purchased, and your yield at time of purchase may be different from the yield shown here. The “locked in” YTW is not guaranteed; you may receive less than the YTW of the bonds in the Bond Account if you sell any of the bonds before maturity or if the issuer defaults on the bond. Public Investing charges a markup on each bond trade. See our Fee Schedule. Bond Accounts are not recommendations of individual bonds or default allocations. The bonds in the Bond Account have not been selected based on your needs or risk profile. See https://public.com/disclosures/bond-account to learn more. Hosted on Acast. See acast.com/privacy for more information.
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