Podcasts about Annals

BONUS: From Waterfall to Flow—Rethinking Mental Models in Software Delivery With Henrik Mårtensson In this BONUS episode, we explore the origins and persistence of waterfall methodology in software development with management consultant Henrik Mårtensson. Based on an article where he details the history of Waterfall, Henrik explains the historical context of waterfall, challenges the mental models that keep it alive in modern organizations, and offers insights into how systems thinking can transform our approach to software delivery. This conversation is essential for anyone looking to understand why outdated methodologies persist and how to move toward more effective approaches to software development. The True Origins of Waterfall "Waterfall came from the SAGE project, the first large software project in history, where they came up with a methodology based on an economic analysis." Henrik takes us on a fascinating historical journey to uncover the true origins of waterfall methodology. Contrary to popular belief, the waterfall approach wasn't invented by Winston Royce but emerged from the SAGE project in the 1950s. Bennington published the original paper outlining this approach, while it was Bell and Tayer who later named it "waterfall" when referencing Royce's work. Henrik explains how gated process models eventually led to the formalized waterfall methodology and points out that an entire generation of methods existed between waterfall and modern Agile approaches that are often overlooked in the conversation. In this segment we refer to:  The paper titled “Production of Large Computer Programs” by Herbert D. Benington (direct PDF link) Updated and re-published in 1983 in Annals of the History of Computing ( Volume: 5, Issue: 4, Oct.-Dec. 1983) Winston Royce's paper from 1970 that erroneously is given the source of the waterfall term. Direct PDF Link. Bell and Thayer's paper “Software Requirements: Are They Really A Problem?”, that finally “baptized” the waterfall process. Direct PDF link.   Mental Models That Keep Us Stuck "Fredrik Taylor's model of work missed the concept of a system, leading us to equate busyness with productivity." The persistence of waterfall thinking stems from outdated mental models about work and productivity. Henrik highlights how Frederick Taylor's scientific management principles continue to influence software development despite missing the crucial concept of systems thinking. This leads organizations to equate busyness with productivity, as illustrated by Henrik's anecdote about 50 projects assigned to just 70 people. We explore how project management practices often enforce waterfall thinking, and why organizations tend to follow what others do rather than questioning established practices. Henrik emphasizes several critical concepts that are often overlooked: Systems thinking Deming's principles Understanding variation and statistics Psychology of work Epistemology (how we know what we know) In this segment, we refer to:  Frederik Taylor's book “The Principles of Scientific Management” The video explaining why Project Management leads to Coordination Chaos James C. Scott's book, “Seeing Like a State” Queueing theory Little's Law The Estimation Trap "The system architecture was overcomplicated, and the organizational structure followed it, creating a three-minute door unlock that required major architectural changes." Henrik shares a compelling story about a seemingly simple feature—unlocking a door—that was estimated to take three minutes but actually required significant architectural changes due to Conway's Law. This illustrates how organizational structures often mirror system architecture, creating unnecessary complexity that impacts delivery timelines. The anecdote serves as a powerful reminder of how estimation in software development is frequently disconnected from reality when we don't account for systemic constraints and architectural dependencies. In this segment, we refer to Conway's Law, the observation that explicitly called out how system architecture is so often linked to organizational structures. Moving Beyond Waterfall "Understanding queueing theory and Little's Law gives us the tools to rethink flow in software delivery." To move beyond waterfall thinking, Henrik recommends several resources and concepts that can help transform our approach to software development. By understanding queueing theory and Little's Law, teams can better manage workflow and improve delivery predictability. Henrik's article on coordination chaos highlights the importance of addressing organizational complexity, while James C. Scott's book "Seeing Like a State" provides insights into how central planning often fails in complex environments. About Henrik Mårtensson Henrik Mårtensson is a management consultant specializing in strategy, organizational development, and process improvement. He blends Theory of Constraints, Lean, Agile, and Six Sigma to solve complex challenges. A published author and licensed ScrumMaster, Henrik brings sharp systems thinking—and a love of storytelling—to help teams grow and thrive. You can link with Henrik Mårtensson on LinkedIn and connect with Henrik Mårtensson on Twitter.

In our recent episode on global burn surgery with Dr. Barclay Stewart and Dr. Manish Yadav, we discussed several cases at Kirtipur Hospital in Nepal to illustrate the global burden of burns and similarities and differences in treating burns at Harborview Medical Center, a level 1 trauma and ABA verified burn center in Seattle, WA and Kirtipur Hospital (Nepal Cleft and Burn Center) in Kathmandu, Nepal. In this episode Dr. Stewart and Dr. Yadav return for an interview by UW Surgery Resident, Paul Herman, sharing insights on how to get involved in global surgery with an emphasis on sustainable participation. Hosts:  Manish Yadav, Kirtipur Hospital, Nepal Barclay Stewart, UW/Harborview Medical Center Paul Herman, UW/Harborview General Surgery Resident, @paul_herm  Tam Pham, UW/Harborview Medical Center (Editor) Learning Objectives 1.     Approaches to global surgery  a.     Describe historical perspectives on global health and global surgery reviewing biases global surgery inherits from global health due to the history of colonialism, neo-colonialism and systemic inequalities b.     Review a recently published framework and evaluation metrics for sustainable global surgery partnerships (GSPs) as described by Binda et al., in Annals of Surgery in March 2024. c.      Provide examples of this framework from a successful global surgery partnership d.     Define vertical, horizontal and diagonal global surgery approaches e.     Share tips for initial engagement for individuals interested in getting involved in global surgery References 1.     Gosselin, R., Charles, A., Joshipura, M., Mkandawire, N., Mock, C. N. , et. al. 2015. “Surgery and Trauma Care”. In: Disease Control Priorities (third edition): Volume 1, Essential Surgery, edited by H. Debas, P. Donkor, A. Gawande, D. T. Jamison, M. Kruk, C. N. Mock. Washington, DC: World Bank. 2.     Qin R, Alayande B, Okolo I, Khanyola J, Jumbam DT, Koea J, Boatin AA, Lugobe HM, Bump J. Colonisation and its aftermath: reimagining global surgery. BMJ Glob Health. 2024 Jan 4;9(1):e014173. doi: 10.1136/bmjgh-2023-014173. PMID: 38176746; PMCID: PMC10773343. https://pubmed.ncbi.nlm.nih.gov/38176746/ 3.     Binda CJ, Adams J, Livergant R, Lam S, Panchendrabose K, Joharifard S, Haji F, Joos E. Defining a Framework and Evaluation Metrics for Sustainable Global Surgical Partnerships: A Modified Delphi Study. Ann Surg. 2024 Mar 1;279(3):549-553. doi: 10.1097/SLA.0000000000006058. Epub 2023 Aug 4. PMID: 37539584; PMCID: PMC10829902.  https://pubmed.ncbi.nlm.nih.gov/37539584/ 4.     Jedrzejko N, Margolick J, Nguyen JH, Ding M, Kisa P, Ball-Banting E, Hameed M, Joos E. A systematic review of global surgery partnerships and a proposed framework for sustainability. Can J Surg. 2021 Apr 28;64(3):E280-E288. doi: 10.1503/cjs.010719. PMID: 33908733; PMCID: PMC8327986. https://pubmed.ncbi.nlm.nih.gov/33908733/ 5.     Frenk J, Gómez-Dantés O, Knaul FM: The health systems agenda: prospects for the diagonal approach. The handbook of global health policy. 2014 Apr 24; pp. 425–439 6.     Davé DR, Nagarjan N, Canner JK, Kushner AL, Stewart BT; SOSAS4 Research Group. Rethinking burns for low & middle-income countries: Differing patterns of burn epidemiology, care seeking behavior, and outcomes across four countries. Burns. 2018 Aug;44(5):1228-1234. doi: 10.1016/j.burns.2018.01.015. Epub 2018 Feb 21. PMID: 29475744. https://pubmed.ncbi.nlm.nih.gov/29475744/ 7.     Strain, S., Adjei, E., Edelman, D. et al. The current landscape of global international surgical rotations for general surgery residents in the United States: a survey by the Association for Program Directors in Surgery's (APDS) global surgery taskforce. Global Surg Educ 3, 77 (2024). https://doi.org/10.1007/s44186-024-00273-2 8.     Francalancia S, Mehta K, Shrestha R, Phuyal D, Bikash D, Yadav M, Nakarmi K, Rai S, Sharar S, Stewart BT, Fudem G. Consumer focus group testing with stakeholders to generate an enteral resuscitation training flipbook for primary health center and first-level hospital providers in Nepal. Burns. 2024 Jun;50(5):1160-1173. doi: 10.1016/j.burns.2024.02.008. Epub 2024 Feb 15. PMID: 38472005; PMCID: PMC11116054. https://pubmed.ncbi.nlm.nih.gov/38472005/ 9.     Shrestha R, Mehta K, Mesic A, Dahanayake D, Yadav M, Rai S, Nakarmi K, Bista P, Pham T, Stewart BT. Barriers and facilitators to implementing enteral resuscitation for major burn injuries: Reflections from Nepalese care providers. Burns. 2024 Oct 28;51(1):107302. doi: 10.1016/j.burns.2024.107302. Epub ahead of print. PMID: 39577105. https://pubmed.ncbi.nlm.nih.gov/39577105/ Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://app.behindtheknife.org/listen

In this episode Gudrun speaks with Nadja Klein and Moussa Kassem Sbeyti who work at the Scientific Computing Center (SCC) at KIT in Karlsruhe. Since August 2024, Nadja has been professor at KIT leading the research group Methods for Big Data (MBD) there. She is an Emmy Noether Research Group Leader, and a member of AcademiaNet, and Die Junge Akademie, among others. In 2025, Nadja was awarded the Committee of Presidents of Statistical Societies (COPSS) Emerging Leader Award (ELA). The COPSS ELA recognizes early career statistical scientists who show evidence of and potential for leadership and who will help shape and strengthen the field. She finished her doctoral studies in Mathematics at the Universität Göttingen before conducting a postdoc at the University of Melbourne as a Feodor-Lynen fellow by the Alexander von Humboldt Foundation. Afterwards she was a Professor for Statistics and Data Science at the Humboldt-Universität zu Berlin before joining KIT. Moussa joined Nadja's lab as an associated member in 2023 and later as a postdoctoral researcher in 2024. He pursued a PhD at the TU Berlin while working as an AI Research Scientist at the Continental AI Lab in Berlin. His research primarily focuses on deep learning, developing uncertainty-based automated labeling methods for 2D object detection in autonomous driving. Prior to this, Moussa earned his M.Sc. in Mechatronics Engineering from the TU Darmstadt in 2021. The research of Nadja and Moussa is at the intersection of statistics and machine learning. In Nadja's MBD Lab the research spans theoretical analysis, method development and real-world applications. One of their key focuses is Bayesian methods, which allow to incorporate prior knowledge, quantify uncertainties, and bring insights to the “black boxes” of machine learning. By fusing the precision and reliability of Bayesian statistics with the adaptability of machine and deep learning, these methods aim to leverage the best of both worlds. The KIT offers a strong research environment, making it an ideal place to continue their work. They bring new expertise that can be leveraged in various applications and on the other hand Helmholtz offers a great platform in that respect to explore new application areas. For example Moussa decided to join the group at KIT as part of the Helmholtz Pilot Program Core-Informatics at KIT (KiKIT), which is an initiative focused on advancing fundamental research in informatics within the Helmholtz Association. Vision models typically depend on large volumes of labeled data, but collecting and labeling this data is both expensive and prone to errors. During his PhD, his research centered on data-efficient learning using uncertainty-based automated labeling techniques. That means estimating and using the uncertainty of models to select the helpful data samples to train the models to label the rest themselves. Now, within KiKIT, his work has evolved to include knowledge-based approaches in multi-task models, eg. detection and depth estimation — with the broader goal of enabling the development and deployment of reliable, accurate vision systems in real-world applications. Statistics and data science are fascinating fields, offering a wide variety of methods and applications that constantly lead to new insights. Within this domain, Bayesian methods are especially compelling, as they enable the quantification of uncertainty and the incorporation of prior knowledge. These capabilities contribute to making machine learning models more data-efficient, interpretable, and robust, which are essential qualities in safety-critical domains such as autonomous driving and personalized medicine. Nadja is also enthusiastic about the interdisciplinarity of the subject — repeatedly changing the focus from mathematics to economics to statistics to computer science. The combination of theoretical fundamentals and practical applications makes statistics an agile and important field of research in data science. From a deep learning perspective, the focus is on making models both more efficient and more reliable when dealing with large-scale data and complex dependencies. One way to do this is by reducing the need for extensive labeled data. They also work on developing self-aware models that can recognize when they're unsure and even reject their own predictions when necessary. Additionally, they explore model pruning techniques to improve computational efficiency, and specialize in Bayesian deep learning, allowing machine learning models to better handle uncertainty and complex dependencies. Beyond the methods themselves, they also contribute by publishing datasets that help push the development of next-generation, state-of-the-art models. The learning methods are applied across different domains such as object detection, depth estimation, semantic segmentation, and trajectory prediction — especially in the context of autonomous driving and agricultural applications. As deep learning technologies continue to evolve, they're also expanding into new application areas such as medical imaging. Unlike traditional deep learning, Bayesian deep learning provides uncertainty estimates alongside predictions, allowing for more principled decision-making and reducing catastrophic failures in safety-critical application. It has had a growing impact in several real-world domains where uncertainty really matters. Bayesian learning incorporates prior knowledge and updates beliefs as new data comes in, rather than relying purely on data-driven optimization. In healthcare, for example, Bayesian models help quantify uncertainty in medical diagnoses, which supports more risk-aware treatment decisions and can ultimately lead to better patient outcomes. In autonomous vehicles, Bayesian models play a key role in improving safety. By recognizing when the system is uncertain, they help capture edge cases more effectively, reduce false positives and negatives in object detection, and navigate complex, dynamic environments — like bad weather or unexpected road conditions — more reliably. In finance, Bayesian deep learning enhances both risk assessment and fraud detection by allowing the system to assess how confident it is in its predictions. That added layer of information supports more informed decision-making and helps reduce costly errors. Across all these areas, the key advantage is the ability to move beyond just accuracy and incorporate trust and reliability into AI systems. Bayesian methods are traditionally more expensive, but modern approximations (e.g., variational inference or last layer inference) make them feasible. Computational costs depend on the problem — sometimes Bayesian models require fewer data points to achieve better performance. The trade-off is between interpretability and computational efficiency, but hardware improvements are helping bridge this gap. Their research on uncertainty-based automated labeling is designed to make models not just safer and more reliable, but also more efficient. By reducing the need for extensive manual labeling, one improves the overall quality of the dataset while cutting down on human effort and potential labeling errors. Importantly, by selecting informative samples, the model learns from better data — which means it can reach higher performance with fewer training examples. This leads to faster training and better generalization without sacrificing accuracy. They also focus on developing lightweight uncertainty estimation techniques that are computationally efficient, so these benefits don't come with heavy resource demands. In short, this approach helps build models that are more robust, more adaptive to new data, and significantly more efficient to train and deploy — which is critical for real-world systems where both accuracy and speed matter. Statisticians and deep learning researchers often use distinct methodologies, vocabulary and frameworks, making communication and collaboration challenging. Unfortunately, there is a lack of Interdisciplinary education: Traditional academic programs rarely integrate both fields. It is necessary to foster joint programs, workshops, and cross-disciplinary training can help bridge this gap. From Moussa's experience coming through an industrial PhD, he has seen how many industry settings tend to prioritize short-term gains — favoring quick wins in deep learning over deeper, more fundamental improvements. To overcome this, we need to build long-term research partnerships between academia and industry — ones that allow for foundational work to evolve alongside practical applications. That kind of collaboration can drive more sustainable, impactful innovation in the long run, something we do at methods for big data. Looking ahead, one of the major directions for deep learning in the next five to ten years is the shift toward trustworthy AI. We're already seeing growing attention on making models more explainable, fair, and robust — especially as AI systems are being deployed in critical areas like healthcare, mobility, and finance. The group also expect to see more hybrid models — combining deep learning with Bayesian methods, physics-based models, or symbolic reasoning. These approaches can help bridge the gap between raw performance and interpretability, and often lead to more data-efficient solutions. Another big trend is the rise of uncertainty-aware AI. As AI moves into more high-risk, real-world applications, it becomes essential that systems understand and communicate their own confidence. This is where uncertainty modeling will play a key role — helping to make AI not just more powerful, but also more safe and reliable. The lecture "Advanced Bayesian Data Analysis" covers fundamental concepts in Bayesian statistics, including parametric and non-parametric regression, computational techniques such as MCMC and variational inference, and Bayesian priors for handling high-dimensional data. Additionally, the lecturers offer a Research Seminar on Selected Topics in Statistical Learning and Data Science. The workgroup offers a variety of Master's thesis topics at the intersection of statistics and deep learning, focusing on Bayesian modeling, uncertainty quantification, and high-dimensional methods. Current topics include predictive information criteria for Bayesian models and uncertainty quantification in deep learning. Topics span theoretical, methodological, computational and applied projects. Students interested in rigorous theoretical and applied research are encouraged to explore our available projects and contact us for further details. The general advice of Nadja and Moussa for everybody interested to enter the field is: "Develop a strong foundation in statistical and mathematical principles, rather than focusing solely on the latest trends. Gain expertise in both theory and practical applications, as real-world impact requires a balance of both. Be open to interdisciplinary collaboration. Some of the most exciting and meaningful innovations happen at the intersection of fields — whether that's statistics and deep learning, or AI and domain-specific areas like medicine or mobility. So don't be afraid to step outside your comfort zone, ask questions across disciplines, and look for ways to connect different perspectives. That's often where real breakthroughs happen. With every new challenge comes an opportunity to innovate, and that's what keeps this work exciting. We're always pushing for more robust, efficient, and trustworthy AI. And we're also growing — so if you're a motivated researcher interested in this space, we'd love to hear from you." Literature and further information Webpage of the group G. Nuti, Lluis A.J. Rugama, A.-I. Cross: Efficient Bayesian Decision Tree Algorithm, arxiv Jan 2019 Wikipedia: Expected value of sample information C. Howson & P. Urbach: Scientific Reasoning: The Bayesian Approach (3rd ed.). Open Court Publishing Company. ISBN 978-0-8126-9578-6, 2005. A.Gelman e.a.: Bayesian Data Analysis Third Edition. Chapman and Hall/CRC. ISBN 978-1-4398-4095-5, 2013. Yu, Angela: Introduction to Bayesian Decision Theory cogsci.ucsd.edu, 2013. Devin Soni: Introduction to Bayesian Networks, 2015. G. Nuti, L. Rugama, A.-I. Cross: Efficient Bayesian Decision Tree Algorithm, arXiv:1901.03214 stat.ML, 2019. M. Carlan, T. Kneib and N. Klein: Bayesian conditional transformation models, Journal of the American Statistical Association, 119(546):1360-1373, 2024. N. Klein: Distributional regression for data analysis , Annual Review of Statistics and Its Application, 11:321-346, 2024 C.Hoffmann and N.Klein: Marginally calibrated response distributions for end-to-end learning in autonomous driving, Annals of Applied Statistics, 17(2):1740-1763, 2023 Kassem Sbeyti, M., Karg, M., Wirth, C., Klein, N., & Albayrak, S. (2024, September). Cost-Sensitive Uncertainty-Based Failure Recognition for Object Detection. In Uncertainty in Artificial Intelligence (pp. 1890-1900). PMLR. M. K. Sbeyti, N. Klein, A. Nowzad, F. Sivrikaya and S. Albayrak: Building Blocks for Robust and Effective Semi-Supervised Real-World Object Detection pdf. To appear in Transactions on Machine Learning Research, 2025 Podcasts Learning, Teaching, and Building in the Age of AI Ep 42 of Vanishing Gradient, Jan 2025. O. Beige, G. Thäter: Risikoentscheidungsprozesse, Gespräch im Modellansatz Podcast, Folge 193, Fakultät für Mathematik, Karlsruher Institut für Technologie (KIT), 2019.

In this episode Gudrun speaks with Nadja Klein and Moussa Kassem Sbeyti who work at the Scientific Computing Center (SCC) at KIT in Karlsruhe. Since August 2024, Nadja has been professor at KIT leading the research group Methods for Big Data (MBD) there. She is an Emmy Noether Research Group Leader, and a member of AcademiaNet, and Die Junge Akademie, among others. In 2025, Nadja was awarded the Committee of Presidents of Statistical Societies (COPSS) Emerging Leader Award (ELA). The COPSS ELA recognizes early career statistical scientists who show evidence of and potential for leadership and who will help shape and strengthen the field. She finished her doctoral studies in Mathematics at the Universität Göttingen before conducting a postdoc at the University of Melbourne as a Feodor-Lynen fellow by the Alexander von Humboldt Foundation. Afterwards she was a Professor for Statistics and Data Science at the Humboldt-Universität zu Berlin before joining KIT. Moussa joined Nadja's lab as an associated member in 2023 and later as a postdoctoral researcher in 2024. He pursued a PhD at the TU Berlin while working as an AI Research Scientist at the Continental AI Lab in Berlin. His research primarily focuses on deep learning, developing uncertainty-based automated labeling methods for 2D object detection in autonomous driving. Prior to this, Moussa earned his M.Sc. in Mechatronics Engineering from the TU Darmstadt in 2021. The research of Nadja and Moussa is at the intersection of statistics and machine learning. In Nadja's MBD Lab the research spans theoretical analysis, method development and real-world applications. One of their key focuses is Bayesian methods, which allow to incorporate prior knowledge, quantify uncertainties, and bring insights to the “black boxes” of machine learning. By fusing the precision and reliability of Bayesian statistics with the adaptability of machine and deep learning, these methods aim to leverage the best of both worlds. The KIT offers a strong research environment, making it an ideal place to continue their work. They bring new expertise that can be leveraged in various applications and on the other hand Helmholtz offers a great platform in that respect to explore new application areas. For example Moussa decided to join the group at KIT as part of the Helmholtz Pilot Program Core-Informatics at KIT (KiKIT), which is an initiative focused on advancing fundamental research in informatics within the Helmholtz Association. Vision models typically depend on large volumes of labeled data, but collecting and labeling this data is both expensive and prone to errors. During his PhD, his research centered on data-efficient learning using uncertainty-based automated labeling techniques. That means estimating and using the uncertainty of models to select the helpful data samples to train the models to label the rest themselves. Now, within KiKIT, his work has evolved to include knowledge-based approaches in multi-task models, eg. detection and depth estimation — with the broader goal of enabling the development and deployment of reliable, accurate vision systems in real-world applications. Statistics and data science are fascinating fields, offering a wide variety of methods and applications that constantly lead to new insights. Within this domain, Bayesian methods are especially compelling, as they enable the quantification of uncertainty and the incorporation of prior knowledge. These capabilities contribute to making machine learning models more data-efficient, interpretable, and robust, which are essential qualities in safety-critical domains such as autonomous driving and personalized medicine. Nadja is also enthusiastic about the interdisciplinarity of the subject — repeatedly changing the focus from mathematics to economics to statistics to computer science. The combination of theoretical fundamentals and practical applications makes statistics an agile and important field of research in data science. From a deep learning perspective, the focus is on making models both more efficient and more reliable when dealing with large-scale data and complex dependencies. One way to do this is by reducing the need for extensive labeled data. They also work on developing self-aware models that can recognize when they're unsure and even reject their own predictions when necessary. Additionally, they explore model pruning techniques to improve computational efficiency, and specialize in Bayesian deep learning, allowing machine learning models to better handle uncertainty and complex dependencies. Beyond the methods themselves, they also contribute by publishing datasets that help push the development of next-generation, state-of-the-art models. The learning methods are applied across different domains such as object detection, depth estimation, semantic segmentation, and trajectory prediction — especially in the context of autonomous driving and agricultural applications. As deep learning technologies continue to evolve, they're also expanding into new application areas such as medical imaging. Unlike traditional deep learning, Bayesian deep learning provides uncertainty estimates alongside predictions, allowing for more principled decision-making and reducing catastrophic failures in safety-critical application. It has had a growing impact in several real-world domains where uncertainty really matters. Bayesian learning incorporates prior knowledge and updates beliefs as new data comes in, rather than relying purely on data-driven optimization. In healthcare, for example, Bayesian models help quantify uncertainty in medical diagnoses, which supports more risk-aware treatment decisions and can ultimately lead to better patient outcomes. In autonomous vehicles, Bayesian models play a key role in improving safety. By recognizing when the system is uncertain, they help capture edge cases more effectively, reduce false positives and negatives in object detection, and navigate complex, dynamic environments — like bad weather or unexpected road conditions — more reliably. In finance, Bayesian deep learning enhances both risk assessment and fraud detection by allowing the system to assess how confident it is in its predictions. That added layer of information supports more informed decision-making and helps reduce costly errors. Across all these areas, the key advantage is the ability to move beyond just accuracy and incorporate trust and reliability into AI systems. Bayesian methods are traditionally more expensive, but modern approximations (e.g., variational inference or last layer inference) make them feasible. Computational costs depend on the problem — sometimes Bayesian models require fewer data points to achieve better performance. The trade-off is between interpretability and computational efficiency, but hardware improvements are helping bridge this gap. Their research on uncertainty-based automated labeling is designed to make models not just safer and more reliable, but also more efficient. By reducing the need for extensive manual labeling, one improves the overall quality of the dataset while cutting down on human effort and potential labeling errors. Importantly, by selecting informative samples, the model learns from better data — which means it can reach higher performance with fewer training examples. This leads to faster training and better generalization without sacrificing accuracy. They also focus on developing lightweight uncertainty estimation techniques that are computationally efficient, so these benefits don't come with heavy resource demands. In short, this approach helps build models that are more robust, more adaptive to new data, and significantly more efficient to train and deploy — which is critical for real-world systems where both accuracy and speed matter. Statisticians and deep learning researchers often use distinct methodologies, vocabulary and frameworks, making communication and collaboration challenging. Unfortunately, there is a lack of Interdisciplinary education: Traditional academic programs rarely integrate both fields. It is necessary to foster joint programs, workshops, and cross-disciplinary training can help bridge this gap. From Moussa's experience coming through an industrial PhD, he has seen how many industry settings tend to prioritize short-term gains — favoring quick wins in deep learning over deeper, more fundamental improvements. To overcome this, we need to build long-term research partnerships between academia and industry — ones that allow for foundational work to evolve alongside practical applications. That kind of collaboration can drive more sustainable, impactful innovation in the long run, something we do at methods for big data. Looking ahead, one of the major directions for deep learning in the next five to ten years is the shift toward trustworthy AI. We're already seeing growing attention on making models more explainable, fair, and robust — especially as AI systems are being deployed in critical areas like healthcare, mobility, and finance. The group also expect to see more hybrid models — combining deep learning with Bayesian methods, physics-based models, or symbolic reasoning. These approaches can help bridge the gap between raw performance and interpretability, and often lead to more data-efficient solutions. Another big trend is the rise of uncertainty-aware AI. As AI moves into more high-risk, real-world applications, it becomes essential that systems understand and communicate their own confidence. This is where uncertainty modeling will play a key role — helping to make AI not just more powerful, but also more safe and reliable. The lecture "Advanced Bayesian Data Analysis" covers fundamental concepts in Bayesian statistics, including parametric and non-parametric regression, computational techniques such as MCMC and variational inference, and Bayesian priors for handling high-dimensional data. Additionally, the lecturers offer a Research Seminar on Selected Topics in Statistical Learning and Data Science. The workgroup offers a variety of Master's thesis topics at the intersection of statistics and deep learning, focusing on Bayesian modeling, uncertainty quantification, and high-dimensional methods. Current topics include predictive information criteria for Bayesian models and uncertainty quantification in deep learning. Topics span theoretical, methodological, computational and applied projects. Students interested in rigorous theoretical and applied research are encouraged to explore our available projects and contact us for further details. The general advice of Nadja and Moussa for everybody interested to enter the field is: "Develop a strong foundation in statistical and mathematical principles, rather than focusing solely on the latest trends. Gain expertise in both theory and practical applications, as real-world impact requires a balance of both. Be open to interdisciplinary collaboration. Some of the most exciting and meaningful innovations happen at the intersection of fields — whether that's statistics and deep learning, or AI and domain-specific areas like medicine or mobility. So don't be afraid to step outside your comfort zone, ask questions across disciplines, and look for ways to connect different perspectives. That's often where real breakthroughs happen. With every new challenge comes an opportunity to innovate, and that's what keeps this work exciting. We're always pushing for more robust, efficient, and trustworthy AI. And we're also growing — so if you're a motivated researcher interested in this space, we'd love to hear from you." Literature and further information Webpage of the group G. Nuti, Lluis A.J. Rugama, A.-I. Cross: Efficient Bayesian Decision Tree Algorithm, arxiv Jan 2019 Wikipedia: Expected value of sample information C. Howson & P. Urbach: Scientific Reasoning: The Bayesian Approach (3rd ed.). Open Court Publishing Company. ISBN 978-0-8126-9578-6, 2005. A.Gelman e.a.: Bayesian Data Analysis Third Edition. Chapman and Hall/CRC. ISBN 978-1-4398-4095-5, 2013. Yu, Angela: Introduction to Bayesian Decision Theory cogsci.ucsd.edu, 2013. Devin Soni: Introduction to Bayesian Networks, 2015. G. Nuti, L. Rugama, A.-I. Cross: Efficient Bayesian Decision Tree Algorithm, arXiv:1901.03214 stat.ML, 2019. M. Carlan, T. Kneib and N. Klein: Bayesian conditional transformation models, Journal of the American Statistical Association, 119(546):1360-1373, 2024. N. Klein: Distributional regression for data analysis , Annual Review of Statistics and Its Application, 11:321-346, 2024 C.Hoffmann and N.Klein: Marginally calibrated response distributions for end-to-end learning in autonomous driving, Annals of Applied Statistics, 17(2):1740-1763, 2023 Kassem Sbeyti, M., Karg, M., Wirth, C., Klein, N., & Albayrak, S. (2024, September). Cost-Sensitive Uncertainty-Based Failure Recognition for Object Detection. In Uncertainty in Artificial Intelligence (pp. 1890-1900). PMLR. M. K. Sbeyti, N. Klein, A. Nowzad, F. Sivrikaya and S. Albayrak: Building Blocks for Robust and Effective Semi-Supervised Real-World Object Detection pdf. To appear in Transactions on Machine Learning Research, 2025 Podcasts Learning, Teaching, and Building in the Age of AI Ep 42 of Vanishing Gradient, Jan 2025. O. Beige, G. Thäter: Risikoentscheidungsprozesse, Gespräch im Modellansatz Podcast, Folge 193, Fakultät für Mathematik, Karlsruher Institut für Technologie (KIT), 2019.

In the April edition of the Annals of Emergency Medicine podcast, Rory and Ryan discuss ketamine for prehospital seizures, firearm injuries in the ED, and the best therapies for headaches.

Use code YDSAMPLE for a free snack pack from Skratch Labs!Support us on Patreon!Is organic food actually healthier—or just more expensive? This week on Your Diet Sucks, Zoë and Kylee break down the real science behind organic food, including what “organic” really means for produce, meat, and packaged snacks. We cover nutrition claims, pesticide exposure, antioxidant levels, and whether organic food impacts inflammation, gut health, or performance. We also dive into the environmental trade-offs of organic farming, the high cost of certification, and why that $19 strawberry feels morally superior. Plus: the truth behind the Dirty Dozen list, who really benefits from organic labels, and how to make food choices that work for your body and your budget.Big thanks to Microcosm Coaching for supporting the pod! We coach humans, not just athletes. Reach out for a free consultation and meet someone who's genuinely on your team.ReferencesBaranski, M., Średnicka-Tober, D., Volakakis, N., Seal, C., Sanderson, R., Stewart, G. B., ... & Leifert, C. (2014). Higher antioxidant and lower cadmium concentrations and lower incidence of pesticide residues in organically grown crops: A systematic literature review and meta-analyses. British Journal of Nutrition, 112(5), 794–811. https://doi.org/10.1017/S0007114514001366Średnicka-Tober, D., Baranski, M., Seal, C., Sanderson, R., Benbrook, C., Steinshamn, H., ... & Leifert, C. (2016). Composition differences between organic and conventional meat: a systematic literature review and meta-analysis. British Journal of Nutrition, 115(6), 994–1011. https://doi.org/10.1017/S0007114515005073Seufert, V., Ramankutty, N., & Foley, J. A. (2012). Comparing the yields of organic and conventional agriculture. Nature, 485(7397), 229–232. https://doi.org/10.1038/nature11069Smith-Spangler, C., Brandeau, M. L., Hunter, G. E., Bavinger, J. C., Pearson, M., Eschbach, P. J., ... & Bravata, D. M. (2012). Are organic foods safer or healthier than conventional alternatives? A systematic review. Annals of Internal Medicine, 157(5), 348–366. https://doi.org/10.7326/0003-4819-157-5-201209040-00007Tuomisto, H. L., Hodge, I. D., Riordan, P., & Macdonald, D. W. (2012). Does organic farming reduce environmental impacts? – A meta-analysis of European research. Journal of Environmental Management, 112, 309–320. https://doi.org/10.1016/j.jenvman.2012.08.018Clark, M., & Tilman, D. (2017). Comparative analysis of environmental impacts of agricultural production systems, agricultural input efficiency, and food choice. Environmental Research Letters, 12(6), 064016. https://doi.org/10.1088/1748-9326/aa6cd5Kniss, A. R., Savage, S. D., & Jabbour, R. (2016). Commercial crop yields reveal strengths and weaknesses for organic agriculture in the United States. PLoS ONE, 11(8), e0161673. https://doi.org/10.1371/journal.pone.0161673

Music can affect emotions, spark memories, and influence mood. In cases of musicogenic epilepsy, music can trigger seizures. In other cases, music may reduce seizure frequency. Dr. Cecilie Nome talks with Dr. Phillip Pearl and Prof. Nigel Osborne about the power of music and its effects on the brain.Links:Nigel Osborne - WikipediaPersonalised music as a treatment for epilepsy - Epilepsy & BehaviorNeuroscience and “real world” practice: music as a therapeutic resource for children in zones of conflict - Osborne - 2012 - Annals of the New York Academy of Sciences - Wiley Online LibraryX-System Overview  Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.Let us know how we're doing: podcast@ilae.org.The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, Instagram, and LinkedIn.

The Filtered Fragments (OG Filtrate)Joel TopfJennie LinSwapnil HiremathSpecial Guest Brad Rovin GN God and second author from The Ohio StateKoyal Jain GN Specialist from UNCAlfred Kim Rheumatologist from Washington UniversityEditing bySimon Topf and Nayan AroraThe Kidney Connection written and performed by by Tim YauShow NotesJoel's monologue One of the most surprising facts of nephrology is that despite conventional wisdom that lupus nephritis is an antibody mediated disease, that over a decade ago, the LUNAR investigtors were unable to find a significant benefit when rituximab was added to conventional therapy. And this was after the equally negative phase 2 trial of rituximab, EXPLORER.In fact, despite this finding rituximab has been able to burough its way into treatment of many nephrologists and rheumatologists as well as the KDIGO guidelines where it is suggested for patients with persistent disease activity or inadequate response to initial standard-of-care therapy.This long conflict is now coming to an end. Obinutuzumab, a newer, better monoclonal antibody targeting the same CD20 that we grew to love with rituximab, but it has a number of advantages.One. It is humanized antibody rather than a chimeric mouse-human antibodyTwo. It's cytotoxicity is not complement dependent an particular advantage if you want to deploy it ina disease where hypocomplementemia is a disease characteristicThree, and most importantly, it causes stronger and deeper b-cell depletion than rituximab. Better B-cell depletion in the blood and tissue.And this brings us to tonight's topic, we had already seen the phase two results of obinutuzumab which, unlike EXPLORER, were positive, we will look at the phase three regency trial. This makes the third novel lupus nephritis drug in the last 4 years. We continue to remake glomerular nephritis.LUNAR: Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study PubmedEXPLORER: Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial PubmedREGENCY: Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis NEJM | NephJCNOBILITY: B-cell depletion with obinutuzumab for the treatment of proliferative lupus nephritis: a randomised, double-blind, placebo-controlled trial Annals of Rheumatic DiseaseComparison of intravenous and subcutaneous exposure supporting dose selection of subcutaneous belimumab systemic lupus erythematosus Phase 3 program PubMed CentralClass 5 lupus nephritis is slow to respond Long-term Use of Voclosporin in Patients with Class V Lupus Nephritis: Results from the AURORA 2 Continuation Study ACR Meeting abstractTubular SecretionsSwap: Young Adult novel I Must Betray You by Ruta Sepetys (Amazon)Koyal: Taekwondo (Wikipedia)Jennie: these unprecedented times Trump NYT: Administration Freezes $1 Billion for Cornell and $790 Million for Northwestern, Officials SayAl: Acquired PodcastBrad: The Feather Thief by Kirk Wallace Johnson (Amazon)Joel: Paradise on Hulu (Wikipedia)

The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:1. Adverse Outcomes Associated With Inhaled Corticosteroid Use in Individuals With Chronic Obstructive Pulmonary Disease. Annals of Family Medicine 2025. Discussion by:Guest:Barbara Yawn, MD, MSc, MPHAdjunct Professor, Department of Family and Community HealthUniversity of Minnesota Former Chief Scientific Officer at the COPD Foundation2. Optimal dietary patterns for healthy aging. Nature Medicine. Discussion by:Guest:Jessica Stieritz, MD Resident– Family Medicine Residency Program Jefferson Health – Abington3. Amount and intensity of daily total physical activity, step count and risk of incident cancer. British Journal of Sports Medicine. Discussion by:Guest:William Callahan, D.O. Associate Director – Family Medicine Residency ProgramJefferson Health – AbingtonMedical Director and Host, Neil Skolnik, MD, is an academic family physician who sees patients and teaches residents and medical students as professor of Family and Community Medicine at the Sidney Kimmel Medical College, Thomas Jefferson University and Associate Director, Family Medicine Residency Program at Abington Jefferson Health in Pennsylvania. Dr. Skolnik graduated from Emory University School of Medicine in Atlanta, Georgia, and did his residency training at Thomas Jefferson University Hospital in Philadelphia, PA. This Podcast Episode does not offer CME/CE Credit. Please visit http://naceonline.com to engage in more live and on demand CME/CE content.

In this episode, my guest is Dr. Vaibhav Diwadkar, professor of Psychiatry and Behavioral Neurosciences at Wayne State University School of Medicine. We discuss the powers and limits of the human brain, the tentative yet evolving role of neuroscience, and the science of thermoregulation in both animals and humans.Our conversation explores the concept of hormesis-enhanced interoceptive refocusing—how combining stressors like cold exposure and breathwork with parasympathetic practices such as meditation or introspection can influence brain function, mood, and perception.We also discuss mental health disorders, drugs, pharmaceuticals, animal research, technology, exercise, the abundance of information and food, and the dynamic relationship between the mind, body, and environment. Connect and Learn MoreProfessor Profile: psychiatry.med.wayne.edu/profile/ax3112LinkedIn:  linkedin.com/in/vaibhav-diwadkar-7ba3107 RESOURCESPAPERS“Brain over body”–A study on the willful regulation of autonomic function during cold exposure , NeuroImage (March 2018)Human regulatory systems in the age of abundance: A predictive processing perspective, Annals of the New York Academy of Sciences (February 2025)The impact of a focused behavioral intervention on brain cannabinoid signaling and interoceptive function: Implications for mood and anxiety, Brain Behavior and Immunity Integrative (January 2024)PEOPLEAndrew HubermanEmerson PughFranz GallMartin Heidegger Otto MusikWim Hof

Episode 189: Intermittent Fasting (Religious and Sports)Future Doctors Carlisle and Kim give recommendations about patients who are fasting for religious reasons, such as Ramadan. They also explain the benefits and risks of fasting for athletes and also debunked some myths about fasting. Dr. Arreaza add input about the side effects of fasting and ways to address them.    Written by Cameron Carlisle, MSIV (RUSM) and Kyung Kim, MSIV (AUC). Editing by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Introduction: In the last episode on fasting (#179), we explored how intermittent fasting (IF) can help manage type 2 diabetes by improving insulin sensitivity, promoting weight loss, and lowering inflammation. We discussed the benefits of methods like 16:8 time-restricted eating and the 5:2 meal plan, and even compared IF to medications like metformin. Today, we're bringing that science into real life. We'll talk about how people fast for religious reasons, like during Ramadan, how athletes use IF to stay in shape, and how we can use IF as a tool in family medicine to support community health and A1c control.Intermittent Fasting in Religious PracticeRamadan just ended on 3/30/25, but this is a great time to talk about the broader role of fasting in religion and health. Many faiths incorporate fasting into spiritual practice and understanding this can help us better support our patients.Islam (Ramadan): Ramadan is a month where Muslims fast from dawn to sunset, focusing on spiritual reflection and self-control. No food or drink is consumed during daylight hours. Despite this, studies have shown that with good planning, fasting during Ramadan does not significantly impair physical performance or metabolic health.Key health tips for patients observing Ramadan:Hydrate well between iftar (sunset) and suhoor (pre-dawn).Break the fast with dates and water to gently replenish energy and electrolytes.Eat balanced meals with complex carbs, protein, and healthy fatsAvoid greasy, heavy foods right after fastingLight exercise (such as a walk) after iftar is beneficialReview medications with a healthcare provider, especially for those on insulin or sulfonylureas.For example: Metformin should be taken when you break your fast and then again before dawn. If its an extended-release metformin, take it at night. Metformin does not cause significant hypoglycemia and can be continued during Ramadan. Basal insulin is advised to be given at Iftar, and the dose should be reduced by 25-35% if the patient is not well managed. And regarding the fast-acting insulin, it requires a little more reading, so you can look it up and learn about it. Judaism: In Judaism, fasting is practiced on days like Yom Kippur and Tisha B'Av, typically lasting 25 hours without food or water. These fasts are spiritual and reflective, and patients with medical conditions may seek guidance on how to participate safely.Christianity: Many Christians fast during Lent, either by abstaining from certain foods or limiting meal frequency. Some practice partial-day fasts or water-only fasts for spiritual renewal.A branch of Christianity known as The Church of Jesus Christ of Latter-day Saintsoften observe a 24-hour fast on the first Sunday of each month, known as Fast Sunday, where they abstain from food and drink and donate the cost of meals to charity. This practice is both spiritual and communal.Cameron: Fasting for religious reasons, when done safely, can align with IF protocols and be culturally sensitive for diverse patients in family medicine.IF in Athletes and PerformanceIntermittent fasting is gaining popularity in the sports world. Athletes are using IF to improve body composition, increase fat oxidation, and enhance metabolic flexibility. A recent study, known as the DRIFT trial and published in Annals of Internal Medicine, found that fasting three non-consecutive days a week led to more weight loss than daily calorie restriction. Participants lost an average of 6.37 pounds more over 12 months.Why? Better adherence. People found the 3-day fasting schedule easier to stick to than counting calories every day.Benefits of IF for athletes:Encourages fat burning (via AMPK activation and GLUT4 upregulation, listen to ep. 179).Helps maintain lean muscle while reducing fat.No major drop in performance when meals and workouts are timed properly.What are some practical tips?Schedule workouts during or just before eating windows.Eat protein-rich meals post-workout.Avoid intense training during long fasts unless adapted.Stay hydrated, especially in hot environments or endurance sports.Broader Applications and Myths Around IFHormonal Effects of IF: In addition to improving insulin sensitivity, IF also affects hormones such as ghrelin (which stimulates hunger, remember it as growling) and leptin (which signals fullness). Over time, IF may help the body regulate appetite better and reduce cravings. IF can also decrease morning cortisol levels, the stress hormone. That's why it's important to monitor sleep, hydration, and stress levels when recommending IF.Circadian Rhythm Alignment: Emerging research shows that aligning eating times with natural light/dark cycles—eating during the day and fasting at night—can improve metabolic outcomes. This practice, known as early time-restricted eating (eTRE), has been shown to lower blood glucose, reduce insulin levels, and improve energy use. Patients who eat earlier in the day tend to have better results than those who eat late at night.Myths and Clarifications on IF:-“Fasting slows metabolism” In fact, short-term fasting may boost metabolism slightly due to increased norepinephrine. -“You can't exercise while fasting.” Many people can safely train during fasted states, especially for moderate cardio or strength training. -“Skipping breakfast is bad.” For some, skipping breakfast is a useful IF strategy—as long as total nutrition is maintained. You can break your fast at 2:00 pm, it does have to be at 7:00 AM.What to Eat When Breaking a FastBreaking a fast properly is just as important as fasting itself. Whether it's after a Ramadan fast or a 16-hour fast, the goal is to replenish energy gently and restore nutrients.Ideal foods to break a fast:Dates and water: provide quick energy, potassium, and fiberSoups: lentil or broth-based soups are gentle on digestionComplex carbs: whole grains like brown rice or oatsLean proteins: chicken, fish, eggs, legumesFruits and vegetables: hydrate and provide fiberHealthy fats: nuts, avocado, olive oilProbiotics: yogurt or kefir for gut supportBalanced meals with carbs, protein, and healthy fats help the body transition smoothly back to a fed state.Using IF in Family Medicine and Community HealthIntermittent fasting can be a practical, cost-effective strategy in family medicine. In areas with high rates of obesity and diabetes, like Kern County, IF offers a lifestyle-based tool to improve metabolic health, especially in underserved populations. IF is free!How IF can help in family medicine:Lower A1c levels: improves insulin sensitivity and glucose controlPromote weight loss: decreases insulin resistance and inflammationReduce medication dependence: fewer meds needed over time for some patientsEncourage patient engagement: flexible and easier to follow than strict calorie countingFit diverse lifestyles: aligns with religious and cultural practicesAddress food insecurity: structured eating windows can help patients stretch limited food resourcesHow to apply IF in clinic:Start the conversation by asking if the patient has heard of IFRecommend simple starting points: 12:12 or 14:10Emphasize hydration and nutrient-dense mealsMonitor labs and symptoms, especially in diabetic patientsAdjust medications to avoid hypoglycemiaProvide follow-up and patient education handouts if possibleWhat if a patient isn't ready to try fasting?For those not ready to commit to intermittent fasting, one effective alternative is walking after meals. A simple 10–20 minute walk post-meal can help stimulate GLUT4 receptors in skeletal muscle, promoting glucose uptake independent of insulin. This reduces the demand on pancreatic beta cells and may help improve blood sugar control over time. This strategy is particularly useful for patients with insulin resistance or early-stage type 2 diabetes.Conclusion: Intermittent fasting is not one-size-fits-all, but it can be a powerful tool for both individual and community health. From Ramadan to race day, IF has a place in family medicine when used thoughtfully. Encourage patients to work with their healthcare providers to find an approach that fits their lifestyle, medical needs, and personal values. IF is a cost-effective toolEven without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:American Academy of Family Physicians. (2022). "Intermittent Fasting: A Promising Treatment for Diabetes." AAFP Community Blog. https://www.aafp.org/pubs/afp/afp-community-blog/entry/intermittent-fasting-a-promising-treatment-for-diabetes.htmlHealthline. (2023). "What Breaks a Fast? Foods, Drinks, and Supplements." https://www.healthline.com/nutrition/what-breaks-a-fast.Sarri KO, Tzanakis NE, Linardakis MK, Mamalakis GD, Kafatos AG. Effects of Greek Orthodox Christian Church fasting on serum lipids and obesity. BMC Public Health. 2003 May 16;3:16. doi: 10.1186/1471-2458-3-16. PMID: 12753698; PMCID: PMC156653. https://pmc.ncbi.nlm.nih.gov/articles/PMC156653/.Shang, Y., et al. (2024). "Effects of Intermittent Fasting on Obesity-Related Health Outcomes: An Umbrella Review." eClinicalMedicine.https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00098-1.Abaïdia AE, Daab W, Bouzid MA. Effects of Ramadan Fasting on Physical Performance: A Systematic Review with Meta-analysis. Sports Med. 2020 May;50(5):1009-1026. doi: 10.1007/s40279-020-01257-0. PMID: 31960369. https://pubmed.ncbi.nlm.nih.gov/31960369/.Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

Measles: It's Back, It's Contagious, and You Probably Haven't Seen It Before In this episode, Kevin and Dr. Lisa Wolf dig into the return of a disease we thought had been eradicated in 2000. In case you missed it—we're in the middle of a national measles outbreak, and chances are high you've never actually seen a real case. Measles is back, and we need to be on high alert, as it remains one of the most contagious diseases in the world. What happens when a patient with a suspicious rash sits in your waiting room for hours? How long does measles hang in the air? (Spoiler: it's longer than you think.) From triage missteps to public health policies, this episode walks through how to identify, isolate, and respond to highly contagious diseases—especially when you've never seen them in real life. We also bust the autism myth (again), talk about vaccine hesitancy, and explore what your ED should be doing to prepare right now. Measles Resources Centers for Disease Control and Prevention. (2023, September 6). Measles signs and symptoms. U.S. Department of Health & Human Services. https://www.cdc.gov/measles/signs-symptoms/index.html Centers for Disease Control and Prevention. (2023, September 6). Photos of measles. U.S. Department of Health & Human Services. https://www.cdc.gov/measles/signs-symptoms/photos.html Child Vaccination Schedule https://www.cdc.gov/vaccines/hcp/imz-schedules/child-adolescent-age.html Vaccinations and Autism Eggertson, L. (2010). Lancet retracts 12-year-old article linking autism to MMR vaccines. CMAJ: Canadian Medical Association Journal, 182(4), E199–E200. https://doi.org/10.1503/cmaj.109-3179 Hviid, A., Hansen, J. V., Frisch, M., & Melbye, M. (2019). Measles, mumps, rubella vaccination and autism: A nationwide cohort study. Annals of Internal Medicine, 170(8), 513–520. https://doi.org/10.7326/M18-2101 Tanne, J. H. (2002). MMR vaccine is not linked with autism, says Danish study. BMJ: British Medical Journal, 325(7373), 1134. Immune Memory Loss & Measles Cohen, J. (2019, May 1). How measles causes the body to ‘forget' past infections by other microbes. Science. https://www.science.org/content/article/how-measles-causes-body-forget-past-infections-other-microbes

In this evidence-packed episode, Dr. Scott Watier and Tommy Welling analyze a brand-new clinical trial comparing 4:3 intermittent fasting versus daily caloric restriction over 12 months. The hosts break down the surprising finding that intermittent fasting participants lost significantly more weight (17 pounds vs 11 pounds) while experiencing a dramatic improvement in their relationship with food, shown by a remarkable two-point reduction in binge eating scores compared to almost no change in the calorie restriction group. They explain why fasting showed better long-term adherence (only 19% dropout rate versus 30% in the calorie counting group) despite both approaches creating the same weekly calorie deficit. The episode highlights how the fasting group was nearly 2.5 times more likely to achieve clinically significant 10% weight loss, and offers practical guidance for adapting this research-backed approach to your own fasting schedule. The hosts also discuss how results might be even better with increased protein intake and resistance training—two factors absent from the original study. Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting! Resources and Downloads: SIGN UP FOR THE DROP OF THE ULTIMATE GUIDE TO BLOOD SUGAR CONTROL GRAB THE OPTIMAL RANGES FOR LAB WORK HERE! - NEW RESOURCE! - December 2024 FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS! SLEEP GUIDE DIRECT DOWNLOAD DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE! Partner Links: Get your FREE BOX OF LMNT hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase here! Get 30% off a Keto-Mojo blood glucose and ketone monitor (discount shown at checkout)! Click here! Our Community: Let's continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them! Article Links: https://www.acpjournals.org/doi/10.7326/ANNALS-24-01631

Agrologist Cory Davis joins me to unpack the environmental toll of animal agriculture—and the enormous potential of plant-based food systems to reduce emissions, reclaim land, and restore ecosystems. Cory brings a systems-level perspective that blends science, ethics, and practical solutions. He also does some serious myth-busting about “sustainable” local meat and “regenerative grazing”. Whether you're a climate advocate or curious about food's environmental impact, this episode will challenge what you thought you knew about sustainable eating. Cory is a licensed professional agrologist with over 10 years of experience in natural resource and environmental management. He is a co-author of “Plant-Powered Protein: Nutrition Essentials and Dietary Guidelines for All Ages” along with Vesanto Melina and Brenda Davis, where he breaks down the environmental impacts of different protein choices. He also recently coauthored a paper in the Annals of Medicine titled "Health Disparities and Climate Change in the Marshall Islands".

Wie viel Muskulatur kannst Du wirklich aufbauen – ohne Deine Gesundheit zu verzocken? Und woran erkennst Du, wie weit Du Dein genetisches Fitness-Potenzial schon ausgereizt hast?Lass uns gemeinsam ein paar gängige Mythen rund ums genetische Muskelaufbaupotenzial entzaubern. Du erfährst, wie stark Du realistischerweise (und ohne Doping) werden kannst, was BMI und FFMI in dem Kontext wirklich aussagen und wie Du Deine Trainingserfolge besser einordnen kannst – basierend auf Wissenschaft, Erfahrung und einer Grafik, die es auf den Punkt bringt.In dieser Folge erfährst Du:Was das genetische Limit im Muskelaufbau tatsächlich bedeutetWie Du den FFMI nutzt, um Deinen Fortschritt greifbar zu machenWarum Social Media oft ein verzerrtes Bild liefertUnd wie eine simple Grafik Dir dabei hilft, smarter zu trainieren – statt härterViel Spaß beim Hören!____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________Ressourcen zur Folge:Vollständiger Artikel mit der erwähnten Grafik zur FolgeAlles über Muskelfasertypen (Folge 265)kostenloser FFMI RechnerFitnessstudio: ScoopWeitere Quellen:Kouri, E. M., Pope, H. G., Katz, D. L., & Oliva, P. (1995). Fat-free mass index in users and nonusers of anabolic-androgenic steroids. Clinical Journal of Sport Medicine, 5(4), 223–228. https://doi.org/10.1097/00042752-199510000-00005Sagoe, D., Molde, H., Andreassen, C. S., Torsheim, T., & Pallesen, S. (2014). The global epidemiology of anabolic-androgenic steroid use: a meta-analysis and meta-regression analysis. Annals of Epidemiology, 24(5), 383–398. https://doi.org/10.1016/j.annepidem.2014.01.009Hubal, M. J., Gordish-Dressman, H., Thompson, P. D., et al. (2005). Variability in muscle size and strength gain after unilateral resistance training. Medicine & Science in Sports & Exercise, 37(6), 964–972. https://doi.org/10.1249/01.mss.0000170469.90461.5fSchoenfeld, B. J., Grgic, J., Ogborn, D., & Krieger, J. W. (2017). Strength and hypertrophy adaptations between low- vs. high-load resistance training: a meta-analysis. Journal of Strength and Conditioning Research, 31(12), 3508–3523. https://doi.org/10.1519/JSC.0000000000002200Grgic, J., Schoenfeld, B. J., Orazem, J., & Sabol, F. (2018). Effects of resistance training frequency on measures of muscle hypertrophy: a systematic review and meta-analysis. Sports Medicine, 48(5), 1207–1220. https://doi.org/10.1007/s40279-018-0872-x Hosted on Acast. See acast.com/privacy for more information.

April 19 is World Liver Day, a day to raise awareness about the health of our often-overlooked yet vital liver. Liver diseases are a leading cause of mortality in the Philippines, accounting for 27.3 per 1,000 deaths, according to a 2023 study published in the Annals of Hepatology.Experts also warn that 10-20% of Filipinos may have non-alcoholic fatty liver disease, which can lead to serious complications if left untreated.To share tips on how to take care of our liver, we spoke with Dr. Maria Vanessa H. De Villa, the first surgeon in the country to perform a pediatric liver transplant and the director of The Medical City's Center for Liver Disease Management and Transplantation.Interview by Edg Adrian EvaAudio editing by Jayson Mariñas

Mid-July, 64 CE, in the heart of Rome, tragedy struck as fire erupted into a massive inferno. Did Emperor Nero, regent at the time, purposely set the city ablaze or merely preside over the disaster?Written by Matthew Reich. Narration by Dr. Nicholas Breyfogle. Video production by Laura Seeger and Dr. Nicholas Breyfogle. A textual version of this video is available at https://origins.osu.edu/read/great-fire-rome. This is a production of Origins: Current Events in Historical Perspective at the Goldberg Center in the Department of History at The Ohio State University and the Department of History at Miami University. Be sure to subscribe to our channel to receive updates about our videos and podcasts. For more information about Origins: Current Events in Historical Perspective, please visit origins.osu.edu. Learn more -Roman History Introduction: Potter, David S. Ancient Rome: A New History. Third Edition. New York, New York: Thames & Hudson, 2018.On the Great Fire: Walsh, Joseph J. The Great Fire of Rome: Life and Death in the Ancient City. Witness to Ancient History. Baltimore: Johns Hopkins University Press, 2019.Dando-Collins, Stephen. The Great Fire of Rome: The Fall of the Emperor Nero and His City. 1. ed. Cambridge, Mass: Da Capo Press, 2010.Ancient Authors: Tacitus, Annals, https://penelope.uchicago.edu/Thayer/e/roman/texts/tacitus/annals/15b*.html Suetonius, The Lives of the Twelve Caesars, https://penelope.uchicago.edu/Thayer/E/Roman/Texts/Suetonius/12Caesars/Nero*.html

Dominique de Werra is an emeritus professor of Operations Research at EPFL (Ecole Polytechnique Federale de Lausanne) in Switzerland. His research fields include Combinatorial Optimization, Graph Theory, Scheduling and Timetabling. After spending a few years as an assistant professor in Management Sciences at the University of Waterloo (Canada) he joined the Math Department of EPFL. He conducted a collection of Operational Research projects (applied as well as theoretical) with a number of industrial partners. He is an associate editor of Discrete Applied Mathematics, Discrete Mathematics, Annals of Operations Research and a member of a dozen of editorial boards of international journals. From 1990 to 2000 Dominique de Werra was the Vice-President of EPFL; he was in charge of the international relations and represented his institution in many academy networks in Europe (like the CLUSTER network of excellence which he chaired). He was also in charge of all education programs of EPFL. He was President of IFORS (the International Federation of Operational Research Societies) from 2010 to 2012. In 1987-1988 he was President of EURO, the European Association of Operational Research Societies. In 1985–1986 he was President of ASRO, the Swiss Operations Research Society. In 1995 he was the laureate of the EURO Gold Medal. He has obtained Honorary Degrees from the University of Paris, the Technical University of Poznan (Poland) and the University of Fribourg (Switzerland). In 2012 he was awarded the EURO Distinguished Service Medal. He published over 200 papers in international scientific journals. He also wrote and edited several books. He was member of many committees in various countries of Europe and America (evaluation of institutions, accreditation, strategic orientation, etc.).

America Out Loud PULSE with Dr. Vaughn & Dr. Tankersley – Dr. Peter Marks, longtime FDA vaccine chief, is out—sparking scrutiny over his role in pushing COVID shots despite safety concerns. Billionaire doctor Patrick Soon-Shiong joins critics, calling for a return to honest medicine. From vaccine mandates to ignored cancer breakthroughs, this exposé reveals the deep flaws and corruption driving today's medical-industrial complex. Truth must come first.

America Out Loud PULSE with Dr. Vaughn & Dr. Tankersley – Dr. Peter Marks, longtime FDA vaccine chief, is out—sparking scrutiny over his role in pushing COVID shots despite safety concerns. Billionaire doctor Patrick Soon-Shiong joins critics, calling for a return to honest medicine. From vaccine mandates to ignored cancer breakthroughs, this exposé reveals the deep flaws and corruption driving today's medical-industrial complex. Truth must come first.

Ingrid Froeher apresenta um caso de dor lombar e púrpura para Joanne Alves e Caio Bastos.Referências: Knezevic, Nebojsa Nick et al. “Low back pain.” Lancet (London, England) vol. 398,10294 (2021): 78-92. doi:10.1016/S0140-6736(21)00733-9Antonov, Dimitar et al. “The rash that becomes purpuric, petechial, hemorrhagic, or ecchymotic.” Clinics in dermatology vol. 38,1 (2020): 3-18. doi:10.1016/j.clindermatol.2019.07.036Jarvik, Jeffrey G, and Richard A Deyo. “Diagnostic evaluation of low back pain with emphasis on imaging.” Annals of internal medicine vol. 137,7 (2002): 586-97. doi:10.7326/0003-4819-137-7-200210010-00010Downie, Aron, et al. "Red flags to screen for malignancy and fracture in patients with low back pain: systematic review." Bmj 347 (2013).https://doh.wa.gov/sites/default/files/legacy/Documents/2700/Coag.pdf?uid=62fc9e6dde835Bannow, Bethany Samuelson, and Barbara A Konkle. “How I approach bleeding in hospitalized patients.” Blood vol. 142,9 (2023): 761-768. doi:10.1182/blood.2021014766Novotny, Richard W et al. “Palpable Purpura.” American family physician vol. 109,3 (2024): 265-267.https://www.tadeclinicagem.com.br/guia/321/amiloidose-manifestacoes-clinicas-e-diagnostico/

In today's episode, Dr. Mitchell Posner, Dr. Sarah Shubeck, and Dr. Jelani Williams on the University of Chicago Medicine's new Comprehensive Cancer Center. Scheduled to open in 2027, the new center is a seven-floor, 575,000-square-foot building planned to have 80 private beds and 90 consultation and outpatient rooms. At the moment, the center is anticipated to see 200,000 outpatient visits and 5000 inpatient admissions annually. This would be the city of Chicago's first freestanding cancer pavilion.How will we ensure that this new center prioritizes the community's needs? In Chicago's South Side, cancer death rates are twice the national average, and cancer is also the second-leading cause of death on the South Side behind heart disease. In this conversation, you'll hear about the center's development, what patients can expect, and most importantly, the Department of Surgery's commitment to ensure the cancer center supports those who are most vulnerable. Dr. Mitchell Posner is the Thomas D. Jones Distinguished Service Professor of Surgery, Chief of the Section of General Surgery, and the Chief Clinical Officer of the University of Chicago Medicine Comprehensive Cancer Center. From clinical trials for cancer treatment to his more than 250 articles, abstracts, and book chapters, Dr. Posner is a leading authority in the management of upper gastrointestinal cancers. He is frequently voted among the country's best doctors. He is the past president of the Society of Surgical Oncology. He is deputy editor of the Annals of Surgical Oncology and section editor for the gastrointestinal cancer section of the journal Cancer. He served as chairman of the Gastrointestinal Committee of the American College of Surgeons Oncology Group (ACOSOG).Dr. Sarah Shubeck is an Assistant Professor in the Department of General Surgery. She is a Breast Surgical oncologist specializing in breast surgery, cancer, and benign disease treatment. In addition to her clinical practice, Dr. Shubeck's research has been published in many journals including Cancer, JAMA Surgery, and Annals of Surgical Oncology.Dr. Jelani Williams is a 5th-year general surgery resident at the University of Chicago. He is an aspiring surgical oncologist and attended the Eastern Virginia Medical School. He has published research on predictive models and surgery for metastatic pancreatic neuroendocrine tumors as well as the use of machine learning to distinguish benign and malignant thyroid nodules amongst other topics. Deep Cuts: Exploring Equity in Surgery comes to you from the Department of Surgery at the University of Chicago, which is located on Ojibwe, Odawa and Potawatomi land.Our executive producer is Tony Liu. Our senior producers are Alia Abiad, Caroline Montag, and Chuka Onuh. Our production team includes Megan Teramoto, Ria Sood, Ishaan Kumar, and Daniel Correa Bucio. Our senior editor and production coordinator is Nihar Rama. Our editorial team also includes Beryl Zhou and Julianna Kenny-Serrano. The intro song you hear at the beginning of our show is “Love, Money Part 2” from Chicago's own Sen Morimoto off of Sooper Records. Our cover art is from Leia Chen.A special thanks this week to Dr. Jeffrey Matthews — for his leadership, vision, and commitment to caring for the most vulnerable in our communities. Let us know — what have you most enjoyed about our podcast. Where do you see room for improvement? You can reach out to us on Instagram @deepcutssurgery. Find out more about our work at deepcuts.surgery.uchicago.edu.

In the March issue of the Annals of Emergency Medicine podcast, Rory and Ryan discuss cephalosporins for outpatient pyelonephritis, ED-initiated buprenorphine programs, cervical cancer screening in the ED and much more.

For this special episode of the Astonishing Healthcare podcast, Andrew Barnell, CEO of Geneoscopy, joins Justin Venneri in the studio for an insightful discussion about colorectal cancer (CRC) screening in observance of National CRC Awareness Month! Andrew explains how he and his "very talented" sister, Erica Barnell, MD, PhD, co-founded Geneoscopy to develop diagnostic tests using RNA biomarkers extracted from stool samples. Their newly FDA-approved test, ColoSense™, provides a non-invasive alternative to traditional colonoscopies.Barnell highlights the rising incidence of CRC in younger adults, which prompted guideline changes to lower the recommended screening age to 45. He stresses the urgent need for increased screening awareness and greater access to screening tools, noting that employers can help overcome barriers to screening through education and by encouraging engagement in wellness programs. Other topics covered include:Over 135,000 people are diagnosed with CRC every year, and despite CRC being one of the most preventable cancers with good long-term survival rates following treatment, 50,000 people die from it annually. Preventive screenings are increasingly covered with no patient out-of-pocket costs, but insurers' expenses are rising.Increasing early screening is crucial: 30-40% of eligible individuals remain unscreened, particularly in the 45-49 age group.Geneoscopy's decentralized clinical trial and overall use of technology to conduct its pivotal FDA approval study virtually, which increased patient diversity and efficiency.Regulatory challenges remain: FDA approval is just one step; Medicare coverage and guideline inclusion are key hurdles.Bringing targeted therapy approaches to autoimmune diseases like IBD to improve patient outcomes and reduce costs is Geneoscopy's next goal.Related ContentMultitarget Stool RNA Test for Colorectal Cancer Screening. Barnell EK, Wurtzler EM, La Rocca J, et al. JAMA. 2023;330(18):1760–1768. doi:10.1001/jama.2023.22231Pharmacogenomics (PGx) 101: What You Need to Know for Rx ProgramsReference Materials/Other Links (courtesy of Geneoscopy)Projected Impact and Cost-Effectiveness of Novel Molecular Blood-Based or Stool-Based Screening Tests for Colorectal Cancer. Ladabaum U, Mannalithara A, Schoen RE, Dominitz JA, Lieberman D. Ann Intern Med. 2024 Dec;177(12):1610-1620. doi: 10.7326/ANNALS-24-00910. Epub 2024 Oct 29. PMID: 39467291.Colorectal Cancer—Patient Version. National Cancer Institute (NCI)Productivity savings from colorectal cancer prevention and control strategies. Bradley CJ, Lansdorp-Vogelaar I, Yabroff KR, Dahman B, Mariotto A, Feuer EJ, Brown ML. Am J Prev Med. 2011 Aug;41(2):e5-e14. doi: 10.1016/j.amepre.2011.04.008. PMID: 21767717; PMCID: PMC3139918.Follow Geneoscopy on LinkedInFor more information about Capital Rx and this episode, please visit Capital Rx Insights.

"Thinking of how tourism is now a major industry for Madeira I started with the now, the field recording submitted to the Sonic Heritage project. Already rhythmic in the sound of the footsteps I looped parts of this, and brought it back in at the end. I really liked the image the recording brought up of walking the narrow Levada (waterways) and the muffled greetings and people saying 'sorry' and 'your welcome' as they squeeze past each other. The World Heritage Site is promoted today for its wildlife, tranquillity and calm, so I also closed the loop with brought in birdsong recorded in the Laurisilva (the World Heritage Site in which the field recording was made) "In the past however, for all the lush and ancient forest, this was essentially part of an industrial landscape, with the Levadas (waterways) carved and built through the rock to facilitate the sugar industry that was developed from the mid 15th century onwards. This industry was also the model for the plantation slavery across the Caribbean, Brazil and the United States that followed. "In the official submission to UNESCO to have the Levadas Designated (submitted 2017, nomination withdrawn 2024) there's no mention of enslaved people being brought to the island for labour: Guanche people from the Canary Islands and Berber people from North Africa at first, then people from West Africa. Given that the carving and construction of the Levadas was hard, dangerous and even deadly work it seems likely it was these people who built them, and not 'heroic' or 'stoic' settlers and farmers as the official submission (and other, often tourist oriented, sources) suggest.  "I therefore wanted to make a piece in which the water running through the Levada holds this memory - inspired by the quiet dripping sound that can just be heard at one point in the original recording, I added my own field recordings of water running through a channel and of (archaeological) excavation, plus a low rustling vegetal sound for the dense forest. At several points Gnawa music recorded in Morrocco seeps through, I don't know if this is temporally or geographically correct for some of the first people brought, enslaved, to Madeira, but I wanted a way to surface this history - and to bring in an aural reminder of hidden histories that lie behind official, 'authorised' heritage discourse." References: Tentative Lists: Levadas of Madeira Island, https://whc.unesco.org/en/tentativelists/6230 UNESCO 46 COM (WHC/24/46.COM/17), Decision: 46 COM 8B.23, https://whc.unesco.org/document/207010 Cristiana Bastos. 2025. Sweetness and exile: Madeiran sugar connections in motion. History and Technology. DOI: 10.1080/07341512.2025.2455245 Sidney M. Greenfield. 1977. Madeira and the beginnings of New World sugar cane cultivation and plantation slavery: a study in institution building. Annals of the New York Academy of Sciences, 292: 536-552. https://doi.org/10.1111/j.1749-6632.1977.tb47771.x Roberto Knight Cavaleiro. 2022. Slaves, sugar and rampant capitalism - Madeira 1440 to 1540, The Portugal News (17 February) Other recordings used: Various field recordings of my own Birdsong in the Laurisilva: recordings by Sacha Julien (Creative Commons, Freesound) Men chanting and playing "Qrageb"Tamegroute, Drâa-Tafilalet, Morocco by ikbenraar (Creative Commons, Freesound) Laurisilva of Madeira reimagined by Lara Band. ——————— This sound is part of the Sonic Heritage project, exploring the sounds of the world's most famous sights. Find out more and explore the whole project: https://www.citiesandmemory.com/heritage

In this episode of The Disrupting Dentistry Podcast, Melissa (USA) and Tabitha (Australia) dive into communication's critical role in improving patient outcomes. From explaining the oral-systemic connection to collaborating with medical professionals, they share actionable strategies to enhance patient engagement and drive whole-body health. You'll learn how patient-centered communication, visual aids, and interdisciplinary collaboration can transform your practice and reduce systemic inflammation. Tune in for practical tips backed by science! What You'll Learn in This Episode: Why effective communication is essential for improving patient compliance and health outcomes Patient-centered communication techniques that enhance understanding and engagement The power of visual aids, including biofilm disclosing and voice-activated periodontal charting How to clearly explain the oral-systemic link to patients The importance of collaborating with other healthcare providers for integrated patient care Link to the episode referneced: The One Where We Talk About Communication Key Takeaways: Use patient-friendly language and open-ended questions to foster better communication. Leverage visual aids and real-time technology to help patients "see" their oral health status. Clearly articulate the connection between oral health and systemic conditions like heart disease and diabetes. Build interdisciplinary relationships to deliver holistic patient care. References Mentioned: Bale, B., & Doneen, A. (2022). Beat the Heart Attack Gene: The Revolutionary Plan to Prevent Heart Disease, Stroke, and Diabetes. Epstein, R. M., et al. (2005). Patient-centered communication and diagnostic testing. Annals of Family Medicine, 3(5), 415-421. Gurenlian, J. R. (2022). Patient-centered care in dental hygiene. Journal of Dental Hygiene, 96(2), 121-127. Ha, J. F., & Longnecker, N. (2010). Doctor-patient communication: A review. Ochsner Journal, 10(1), 38-43. Ide, M., et al. (2016). Periodontitis and pregnancy outcomes. Journal of Clinical Periodontology, 43(6), 524-530. Liccardo, D., et al. (2019). Periodontal disease and systemic inflammation. International Journal of Molecular Sciences, 20(6), 1414. Patel, N., et al. (2015). Real-time patient data and adherence. Journal of the American Medical Informatics Association, 22(1), 74-80. Slack-Smith, L., et al. (2017). Interdisciplinary dental and medical collaboration. Australian Dental Journal, 62(1), 115-121. Slade, G. D., et al. (2020). Oral health and systemic disease links. Australian Dental Journal, 65(1), 58-64. van der Sluijs, E., et al. (2018). Biofilm disclosure and patient compliance. International Journal of Dental Hygiene, 16(3), 297-304. Connect With Us: Listen wherever you get your podcasts If you enjoyed this content, please leave us a review Follow us on Instagram: @DisruptingDentistryPodcast Subscribe and leave a review on your favorite podcast platform. Share this episode with your dental colleagues! Next Episode Teaser: Stay tuned for our next episode, where we explore how to prevent gingivitis by making it "sexy."

Send us a text✨ FREE LEARNING RESOURCES FOR A YEAR! - https://irishpagan.school/freeIn this deep dive into the ancient figure of Crom Cruach, Jon O'Sullivan from the Irish Pagan School explores the lore, legends, and mystery surrounding this lesser-known Irish deity. Crom Cruach, an enigmatic figure from Ireland's pre-Christian past, is mentioned in texts like the Annals of the Four Masters and the Metrical Dindshenchas, but much of what we know is fragmentary and colored by Christian reinterpretation. Was Crom Cruach a fearsome idol demanding human sacrifice, or a misunderstood deity associated with fertility, prosperity, and abundance?✨ Irish Pagan Resources Checklist available NOW - https://irishpagan.school/checklist/

America Out Loud PULSE with Dr. Vaughn & Dr. Tankersley – In July 2024, the Annals of Internal Medicine had an article that stated the obvious that our profession is in a moral crisis. Thus, it called for a return to humility. Given the generational headwinds that have developed, we can only hope and pray that science returns to the fundamentals, beginning with a penitent approach led by honest people...

America Out Loud PULSE with Dr. Vaughn & Dr. Tankersley – In July 2024, the Annals of Internal Medicine had an article that stated the obvious that our profession is in a moral crisis. Thus, it called for a return to humility. Given the generational headwinds that have developed, we can only hope and pray that science returns to the fundamentals, beginning with a penitent approach led by honest people...

Dawn Gross speaks at the 2025 Public Forum on Healing with Integrative Cancer Care in February. The gathering was designed to bridges wisdom traditions with emerging frontiers in healing. This year's forum explores transformation through the intersections of integrative cancer care with consciousness and healing arts, featuring distinguished speakers and practitioners from diverse backgrounds. The day included engaging presentations on patient advocacy, expressive arts, and innovative approaches to cancer care. Dawn Gross, MD, PhD, (aka DrAsYouWish) is a national thought leader in Hospice & Palliative Medicine, Writer, Podcaster and Magic Wand Bearer, who pioneers revolutionary palliative medicine as the art of patient care, scientific curiosity and storytelling. Medical director of ANX Hospice and UCSF Palliative Care physician, Dawn earned her MD and PhD in immunology from Tufts University and completed her fellowship training in hematology with an emphasis in bone marrow transplant at Stanford University. She transitioned to the field of hospice and palliative medicine after her father died in 2006. Dawn considers grief an injury and has developed a novel approach to its healing in what she refers to as the ICU “ISEEYOU for the Soul.” She is the creator and host of the radio program, Dying to Talk. Her writing has been published widely including in The New York Times, JAMA, Science and Annals of Internal Medicine. She is an internationally invited speaker most recently sharing true stories from the bedside about what matters most in her 2024 TEDx talk “Ask. The Time is Now” and her new book, Heart Sounds: How a Stethoscope, A Magic Wand, and a Fishing Pole Teach Us to Listen for What Matters Most. Learn more at: www.drasyouwish.com The New School at Commonweal is a collaborative learning community offering conversations about nature, culture, and inner life---so that we can all find meaning, meet inspiring people, and explore the beauty and grief of our changing world. Please like/follow our YouTube channel for more great podcasts. Find out more about The New School at Commonweal on our website: tns.commonweal.org. And like/follow our Soundcloud channel for more great podcasts.

Step into the future of primary care with Artificial Intelligence and Machine Learning (AI/ML). In this episode, you'll discover how these transformative technologies are revolutionizing healthcare as three expert voices from STFM's cutting-edge Artificial Intelligence and Machine Learning for Primary Care Curriculum reveal insider strategies to slash administrative burden—and maybe even carve out time for your dream vacation. Whether you're an educator eager to innovate, or a clinician ready to lead your team in implementing new tools, this dynamic panel delivers practical tips, ethical insights, and the inspiration you need to confidently participate in the AI revolution.Our Panelists:Cornelius James, MDJaky Kueper, PhDWinston Liaw, MD, MPHHosted by Omari A. Hodge, MD, FAAFP and Jay-Sheree Allen Akambase, MDCopyright © Society of Teachers of Family Medicine, 2025Resources:Artificial Intelligence and Machine Learning for Primary Care Curriculum (AiM-PC)Upcoming Opportunity - Ethical Use of AI in the Family Medicine Clinic - STFM Webinar scheduled for May 30, 2025 at 12pm CTArtificial Intelligence and Family Medicine: Better Together - Fam Med Generative Artificial Intelligence and Large Language Models in Primary Care Medical Education - Fam Med Artificial Intelligence-Prompted Explanations of Common Primary Care Diagnoses - PRiMER Guest Bio:Cornelius James, MDDr. James is an Assistant Professor in the Departments of Internal Medicine, Pediatrics and Learning Health Sciences at the University of Michigan (U-M). He is a general internist and a general pediatrician practicing as a primary care physician. He holds the James O. Woolliscroft, MD Endowment in Humane Patient Care.Dr. James has served in many educational roles across the continuum of medical education, including serving as the director of the University of Michigan Medical School evidence-based medicine curriculum, and an Associate Program Director for the U-M Internal Medicine Residency Program. He also serves on local and national committees, including the U-M Clinical Intelligence Committee and the International Advisory Committee for Artificial Intelligence. In multiple years Dr. James has been identified as one of the top teachers in the Department of Internal Medicine. In addition, in 2022 he received the Kaiser Permanente Excellence in Teaching award, the most prestigious teaching award given by the U-M medical school. Dr. James has completed the American Medical Association (AMA) Health Systems Science Scholars program, and he was also one of ten inaugural 2021 National Academy of Medicine Scholars in Diagnostic Excellence. His research interests include augmenting clinical reasoning with artificial intelligence, and equitable implementation of safe and effective digital health tools into clinical practice.His work has been published in JAMA, Annals of Internal Medicine, Academic Medicine, the Journal of General Internal Medicine, Cell Reports, and more. Jaky Kueper, PhDJaky Kueper, PhD, is an epidemiologist and computer scientist with the Scripps Research Digital Trials Center. Her work in AI for primary care ranges from investigating primary care AI needs and priorities to co-developing AI solutions with Community Health Centres. She's also been engaged in several AI for heal

Much like deprescribing, we plan to revisit certain high impact and dynamic topics frequently.  Substance use disorder is one of those complex issues in which clinical practice is changing rapidly.  You can listen to our prior podcasts on substance use disorder here, here, here, and here. Today we talk with experts Janet Ho, Sach Kale, and Julie Childers about opioid use disorder and serious illness.  We address: Why is caring for patients with this overlap so hard?  Inspired by Dani Chammas's paper in Annals of Internal Medicine titled, “Wishing for a no show” we talk about countertransference: start by asking yourself, “Why am I having difficulty? What is making this hard for me?”  Sach Kale set up an outpatient clinic focused on substance use disorder for patients with cancer. Why? How? What do they do? Do you need to be an addiction medicine trained physician to start such a clinic (no: Sach is not).  See Sach's write up about setting up this clinic in JPSM. What is harm reduction and how can we implement it in practice?  One key tenet of harm reduction we return to multiple times on this podcast: Accountability without termination (or, in more familiar language, without abandonment). When to consider bupenorphine vs methadone?  Why the field is moving away from prescribing methadone to bupenorphine; how to manage patients prescribed methadone for opioid use disorder who then develop serious and painful illness - should we/can we split up the once daily dosing to achieve better pain control? Who follows the patient once the cancer goes into remission? Who will prescribe the buprenorphine then?  Or when it progresses - will hospice pay? And so much more: maybe not the oxycodone for breakthrough; when the IV dilaudid is the only thing that works; pill counts and urine drug tests; the 3 Ps approach (pain, pattern, prognosis); stimulant use disorder; a forthcoming VitalTalk section… Thanks to the many questions that came in on social media from listeners in advance of this podcast.  We all have questions.  We addressed as many of your listener questions as we could. We could have talked for 4 hours and will definitely revisit this issue! Sometimes the drugs don't work. -Alex: @alexsmithmd.bsky.social

Trauma is a universal experience, and our approach as health care providers to trauma should be universal as well. That's my main take-home point after learning from our three guests today when talking about trauma-informed care, an approach that highlights key principles including safety, trustworthiness, peer support, collaboration, empowerment, and cultural sensitivity. With that said, there is so much more that I learned from our guests for this trauma-informed care podcast. Our guests include Mariah Robertson, Kate Duchowny, and Ashwin Kotwal. Mariah discussed her JAGS paper on applying a trauma-informed approach to home visits. Kate and Ashwin talked about their research on the prevalence of lifetime trauma and its association with physical and psychosocial health among adults at the end of life. We also explored several questions with them, including how to define trauma, its prevalence in older adults, the impact of past traumatic experiences, the potential triggers of trauma screening, and the application of trauma-informed principles in clinical practice. If you want a deeper dive, check out the following resources: Our “Nature of Suffering” podcast with BJ Miller and Naomi Saks Dani Chammas' Annals paper on countertransference and why we shouldn't say “that the patient was difficult rather than that I felt frustrated.”  A great Curbsiders podcast episode on Trauma-informed care with Megan Gerber CAPC's Trauma-informed care toolkit Mariah's article on Home-Based Care for LGBTQ or another diverse gender identity Older Adults

This week Dr. Nathan Kalman-Lamb and Dr. Derek Silva drop in to talk about 1993's The Program, starring James Caan, Omar Epps, and Halle Berry. This movie was way ahead of its time in its discussions of Name, Image, and Likeness (NIL), concussions, and race and sexual dynamics on campus. We talk about all of this and the cost to college athletes to play the game. About our guests:Nathan Kalman-Lamb's  scholarly work sits at the intersection of social theory and the sociology of sport, with a particular focus on labor, racism, and exploitation. His most recent book Game Misconduct: Injury, Fandom, and the Business of Sport, based on qualitative interviews with former professional hockey players and fans of the sport, uses Marxist-Feminist social reproduction theory to explore how the political economy of sports like hockey is predicated on an affective transfer from athletic workers to fans through the physical sacrifice that is fundamental to these 'games.'Derek Silva's areas of interest include sociocultural studies of sport, critical sociology and criminology, labour, racism, and inequality. My work can be found in the peer-reviewed journals Critical Sociology, Punishment and Society, Crime, Media, Culture, Sociology of Sport Journal, Journal of Sport & Social Issues, Policing & Society, Annals of Leisure Research, Social Science & Medicine – Qualitative Research in Health, Sociological Forum, Race & Class, Educational Gerontology, and in media outlets such as TIME Magazine, Los Angeles Times, The Guardian, The Daily Beast, The Chronicle of Higher Education, ​Jacobin Magazine, and The Baffler Magazine. 

The practice of growing plants in water rather than soil isn't new, though early examples are difficult to substantiate. In the 1930s, hydroponic plant culture made headlines, but the field also had conflict among researchers. Research: Bacon, Francis. “Sylva sylvarum; or, A natural history, in ten centuries. Whereunto is newly added the History natural and experimental of life and death, or of the prolongation of life.” London. 1670. https://archive.org/details/sylvasylvarumorn00baco/page/116/mode/2up Britannica, The Editors of Encyclopaedia. "Hanging Gardens of Babylon". Encyclopedia Britannica, 13 Jan. 2025, https://www.britannica.com/place/Hanging-Gardens-of-Babylon Britannica, The Editors of Encyclopaedia. "chinampa". Encyclopedia Britannica, 26 May. 2017, https://www.britannica.com/topic/chinampa Britannica, The Editors of Encyclopaedia. "Julius von Sachs". Encyclopedia Britannica, 28 Sep. 2024, https://www.britannica.com/biography/Julius-von-Sachs. Ebel, Roland. "Chinampas: An Urban Farming Model of the Aztecs and a Potential Solution for Modern Megalopolis". HortTechnology hortte 30.1 (2020): 13-19. < https://doi.org/10.21273/HORTTECH04310-19 Gericke, W. F. “The Complete Guide To Soilless Gardening.” Prentice Hall. 1940. https://archive.org/details/in.ernet.dli.2015.271694/page/n1/mode/2up Gericke, W. F. “The Meaning of Hydroponics.” Science101,142-143. 1945. https://www.science.org/doi/10.1126/science.101.2615.142 "General Mills' Big Gamble on Indoor Farming." Dun's Review. 1979. https://www.nal.usda.gov/sites/default/files/card-image/DunsReviewGeneralMillsImage.jpg “Growing Crops Without Soil.” United States Department of Agriculture. Agricultural research service. June 1965. https://www.nal.usda.gov/sites/default/files/card-image/RaisingCropsWithoutSoil1965_0.jpg Hall, Loura. “NASA Research Launches a New Generation of Indoor Farming.” NASA. Nov. 23, 2021. https://www.nasa.gov/technology/tech-transfer-spinoffs/nasa-research-launches-a-new-generation-of-indoor-farming/ Hoagland, D.R. and D.I. Arnon. “The Water-culture Method for Growing Plants Without Soil.” Berkeley. 1950. https://archive.org/details/watercultureme3450hoag/page/n5/mode/2up “A Hydroponic Farm on Wake Island.” Science87,12-3. (1938). DOI:1126/science.87.2263.12.u Janick, Jules et al. “The cucurbits of mediterranean antiquity: identification of taxa from ancient images and descriptions.” Annals of botany vol. 100,7 (2007): 1441-57. doi:10.1093/aob/mcm242 Silvio, Caputo. “History, Techniques and Technologies of Soil-Less Cultivation.” Springer, Cham. https://doi.org/10.1007/978-3-030-99962-9_4 Singer, Jesse. “A Hydroponics Timeline. Garden Culture Magazine. Feb. 8, 2021. https://gardenculturemagazine.com/a-brief-overview-of-the-history-of-hydroponics/#:~:text=1627:%20Sylva%20Sylvarum,Chemist%20Jean%20Baptist%20van%20Helmont Stanhill, G. "JOHN WOODWARD—A NEGLECTED 17TH CENTURY PIONEER OF EXPERIMENTAL BOTANY". Israel Journal of Plant Sciences 35.3-4 (1986): 225-231. https://doi.org/10.1080/0021213X.1986.10677056 Stuart, Neil W. “About Hydroponics.” Yearbook of Agriculture, U.S. Department of Agriculture. 1947. Accessed online: https://archive.org/details/yoa1947/page/289/mode/2up Taylor, Judith. “National Nutrition Month: Hydroponics feed ailing WWII Army Air Forces personnel.” Air Force Medical Service. March 26, 2014. https://www.airforcemedicine.af.mil/News/Article/582803/national-nutrition-month-hydroponics-feed-ailing-wwii-army-air-forces-personnel/ “Plants Without Soil.” Brooklyn Eagle. Feb. 28, 1937.https://www.newspapers.com/image/52623587/?match=1&terms=hydroponics “Hydroponics.” Courier-Journal. March 2, 1937. https://www.newspapers.com/image/107727971/?match=1&terms=hydroponics See omnystudio.com/listener for privacy information.

Dr. Kevin Masters is a clinical psychologist and a leader in the fields of health psychology and behavioral medicine. He is a professor of psychology at the University of Colorado Denver. He served a term as the Editor-in-Chief of Annals of Behavioral Medicine. He is a Fellow of the American Psychological Association and the Society of Behavioral Medicine. In this conversation with Vikas, Dr Masters discusses why it is difficult to take up a fitness habit and sustain and what are the key reasons that build a habit. The conversation will delight you and hopefully teach you a few things to continue with the love of running.About Vikas Singh:Vikas Singh, an MBA from Chicago Booth, worked at Goldman Sachs, Morgan Stanley, APGlobale, and Reliance before coming up with the idea of democratizing fitness knowledge and helping beginners get on a fitness journey. Vikas is an avid long-distance runner, building fitpage to help people learn, train, and move better.For more information on Vikas, or to leave any feedback and requests, you can reach out to him via the channels below:Instagram: @vikas_singhhLinkedIn: Vikas SinghTwitter: @vikashsingh101Subscribe To Our Newsletter For Weekly Nuggets of Knowledge!

Dr. Daniel Hale Williams is often described as the first person to successfully perform an open-heart surgery. That's not entirely accurate, but he was still a surgical innovator, and he was also a huge part of the Black Hospital Movement. Research: "Daniel Hale Williams." Contemporary Black Biography, vol. 2, Gale, 1992. Gale In Context: U.S. History, link.gale.com/apps/doc/K1606000260/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=c4ae7664. Accessed 28 Jan. 2025. "Daniel Hale Williams." Notable Black American Men, Book II, edited by Jessie Carney Smith, Gale, 1998. Gale In Context: U.S. History, link.gale.com/apps/doc/K1622000479/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=80e75e7e. Accessed 28 Jan. 2025. Buckler, Helen. “Doctor Dan: Pioneer in American Surgery.” Little, Brown and Company. 1954. Cobb, W M. “Daniel Hale Williams-Pioneer and Innovator.” Journal of the National Medical Association vol. 36,5 (1944): 158-9. COBB, W M. “Dr. Daniel Hale Williams.” Journal of the National Medical Association vol. 45,5 (1953): 379-85. Cook County Health. “Celebrating 30 Years: Provident Hospital of Cook County.” https://cookcountyhealth.org/provident-hospital-30th-anniversary/ Gamble, Vanessa Northington. “Making a place for ourselves : the Black hospital movement, 1920-1945.” New York : Oxford University Press. 1995. Gamble, Vanessa Northington. “The Provident Hospital Project: An Experiment in Race Relations and Medical Education.” Bulletin of the History of Medicine, WINTER 1991. Via JSTOR. https://www.jstor.org/stable/44442639 Gordon, Ralph C. “Daniel Hale Williams: Pioneer Black Surgeon and Educator.” Journal of Investigative Surgery, 18:105–106, 2005. DOI: 10.1080/08941930590956084 Hughes, Langston. “Famous American Negroes.” Dodd Mead. 1954. Jackson State University. “Who Was Dr. Daniel Hale Williams?” https://www.jsums.edu/gtec/dr-daniel-hale-williams/ Jefferson, Alisha J. and Tamra S. McKenzie. “Daniel Hale Williams, MD: ‘A Moses in the profession.’” American College of Surgeons CC2017 Poster Competition. 2017. Office of the Illinois Secretary of State. “51. Dr. Daniel Hale Williams Letter to Governor Joseph Fifer (1889).” 100 Most Valuable Documents at the Illinois State Archives. https://www.ilsos.gov/departments/archives/online_exhibits/100_documents/1889-williams-letter-gov.html Olivier, Albert F. “In Proper Perspective: Daniel Hale Williams, M.D.” Annals of Thoracic Surgery. Volume 37, Issue 1p96-97 January 1984. https://www.annalsthoracicsurgery.org/article/S0003-4975(10)60721-7/fulltext Raman, Jai. “Access to the Heart – Evolution of surgical techniques.” Global Surgery. Vol. 1, No. 2. doi: 10.15761/GOS.1000112 Rock County, Wisconsin. “Dr. Daniel Hale Williams.” https://legacy.co.rock.wi.us/daniel-hale-williams Summerville, James. “Educating Black doctors : a history of Meharry Medical College.” University of Alabama Press. https://archive.org/details/educatingblackdo0000summ/ The Provident Foundation. “History- Dr. Daniel Hale Williams.” https://provfound.org/index.php/history/history-dr-daniel-hale-williams “Early Chicago: Hospital of Hope.” DuSable to Obama: Chicago’s Black Metropolis. https://www.wttw.com/dusable-to-obama/provident-hospital See omnystudio.com/listener for privacy information.

Welcome to Dev Game Club, where this week we continue our series on 1999's Outcast. Tim can't get enough of the voxels, and we dive a little bit into combat, mounts, and structure. Dev Game Club looks at classic video games and plays through them over several episodes, providing commentary. Sections played: Mostly through Shamazaar Issues covered: revisiting Defeating Games for Charity, the work behind the event, launch of VGHF library, accepting the voxels, possible benefits of voxels, how to represent transfer, back to metaballs, generating noise in the voxels, collision and voxels, looking unlike other games of the time, leaving out polygons for the voxels to show through, avoiding the enemies vs blasting, apparent resource scarcity, weak stealth, projectile-based shooting, combat and missing all the time, enjoying dodging but hating missing, abstraction in games, enemies dropping guns that disappear, voice work, stand-out characters, having fun with the NPCs, not being too self-serious, investigating the twon-ha, the different aesthetics of European games, a flexible mount, stumbling on the quest log, skipping ahead in the knowledge tree, seeing games in the same family, a milieu or scene, what were the game inputs that got you to this game, coming at ideas from different directions, German dubbing, the voice of Pey'j, adding legitimization, the music.  Games, people, and influences mentioned or discussed: BioStats, Mark Garcia, Artimage, Final Fantasy VI, Video Game History Foundation, Phil Salvador, Minecraft, Starfighter, Steve Ash, Spore, System Shock 2, DOOM (1993), CliffyB, Chess, Annals of the Grand Historian, Arnold Schwarzeneggar, Bruce Willis, Halo, Dark Crystal, Beyond Good and Evil, Rayman, Ultima (series), Populous, Peter Molyneux, Sid Meier, Civilization (series), Vitor, Assassin's Creed (series), David Gasman, Star Wars, John Williams, Dark Souls 2, Kirk Hamilton, Aaron Evers. Next time: More Outcast Twitch: timlongojr Discord DevGameClub@gmail.com

Sugar-sweetened beverages, the epidemiology of driving after an ICD, BP measurements, and massive EBM lesson in EVT for acute stroke are the topics John Mandrola, MD, discusses in today's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Sugar-Sweetened Beverages Sugary Drinks Fuel Millions of Diabetes and CVD Cases https://www.medscape.com/viewarticle/sugary-drinks-fuel-millions-diabetes-and-cvd-cases-2025a10002wr Nature Medicin;e Epidemiologic Study https://www.nature.com/articles/s41591-024-03345-4 JAMA-Network Open;  Beverage Tax Observational Study https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2829505 Lancet Regional Health; Beverage Tax Philadelphia EHR 10.1016/j.lana.2024.100906 II. Driving With an ICD JACC Electrophysiology paper https://doi.org/10.1016/j.jacep.2024.12.002 Earlier HEART paper https://heart.bmj.com/content/110/24/1401 III. Blood Pressure Measurements and Simple RCTs BP Readings in Noisy Market as Good as Quiet Office? https://www.medscape.com/viewarticle/bp-readings-noisy-market-good-quiet-office-2025a10002z0 Annals of Internal Medicine Study https://www.acpjournals.org/doi/10.7326/ANNALS-24-00873 IV. A Big Shake-up in Interventional Stroke Care Endovascular Therapy Fails to Show Benefit in Distal Occlusion Stroke  https://www.medscape.com/viewarticle/endovascular-therapy-fails-show-benefit-distal-occlusion-2025a100035u ESCAPE-MeVO https://www.nejm.org/doi/full/10.1056/NEJMoa2411668 DISTAL trial https://www.nejm.org/doi/full/10.1056/NEJMoa2408954 J. Mocco Editorial https://www.nejm.org/doi/full/10.1056/NEJMe2500492 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

In this month's Annals of Emergency Medicine podcast, Ryan and Rory ring in the New Year discussing the ideal paralytic in RSI, GI risk assessment scores and much more.

This is a special edition of the MCHD Paramedic Podcast. Ginger Locke, of the absolutely amazing Medic Mindset podcast, invited Dr. Patrick on to discuss rate control of rapid atrial fibrillation in the prehospital setting. She was gracious enough to share the audio for a dual release. This episode has been out in the world on Medic Mindset for a couple of months, but we wanted to offer it to our MCHD Paramedic Podcast listeners as well. Also, like, subscribe to and follow Medic Mindset wherever you listen to podcasts. REFERENCES 1. https://medicmindset.com 2. Elam, K., & Bolar-Softich, K. L. (1997). Dilemmas in the acute pharmacologic treatment of uncontrolled atrial fibrillation. The American journal of emergency medicine, 15(4), 418–419. 3. Abarbanell, N. R., & Marcotte, M. A. (1997). Prehospital use of intravenous diltiazem (cardizem Lyo-Ject) in the treatment of rapid atrial fibrillation. The American journal of emergency medicine, 15(6), 618–619. 4. Abarbanell, N. R., Marcotte, M. A., Schaible, B. A., & Aldinger, G. E. (2001). Prehospital management of rapid atrial fibrillation: recommendations for treatment protocols. The American journal of emergency medicine, 19(1), 6–9. 5. Wang, H. E., O'connor, R. E., Megargel, R. E., Schnyder, M. E., Morrison, D. M., Barnes, T. A., & Fitzkee, A. (2001). The use of diltiazem for treating rapid atrial fibrillation in the out-of-hospital setting. Annals of emergency medicine, 37(1), 38–45. 6. Luk, J. H., Walsh, B., & Yasbin, P. (2013). Safety and efficacy of prehospital diltiazem. The western journal of emergency medicine, 14(3), 296–300. 7. Rodriguez, A., Hunter, C. L., Premuroso, C., Silvestri, S., Stone, A., Miller, S., Zuver, C., & Papa, L. (2019). Safety and Efficacy of Prehospital Diltiazem for Atrial Fibrillation with Rapid Ventricular Response. Prehospital and disaster medicine, 34(3), 297–302. 8. Fornage, L. B., O'Neil, C., Dowker, S. R., Wanta, E. R., Lewis, R. S., & Brown, L. H. (2024). Prehospital Intervention Improves Outcomes for Patients Presenting in Atrial Fibrillation with Rapid Ventricular Response. Prehospital emergency care, 28(7), 910–919.

Today's show is sponsored by Americans for Free Choice in Medicine -- https://www.afcm.orgDr. Adalja is an expert on infectious disease, emergency preparedness, pandemics, and the intersections of public health and national security. is a board-certified physician in internal medicine, emergency medicine, infectious diseases, and critical care medicine. Dr. Adalja's expertise is frequently sought by international and national media.He has also published in such journals as the New England Journal of Medicine, JAMA, Journal of Infectious Diseases, Clinical Infectious Diseases, Emerging Infectious Diseases, Annals of Emergency Medicine, and Health Security.Dr. Adalja is a Fellow of the Infectious Diseases Society of America, the American College of Physicians, and the American College of Emergency Physicians. He is a member of various medical societies, including the American Medical Association, the HIV Medicine Association, and the Society of Critical Care Medicine.Dr. Adalja is a native of Butler, Pennsylvania, and actively practices infectious disease, critical care, and emergency medicine in the Pittsburgh metropolitan area.Dr. Adalja is the Chairman of the board of Americans for Free Choice in Medicine.Reinier Schuur is the Executive Director of AFCM. He holds a PhD in Philosophy from the University of Birmingham in the United Kingdom, where he specialized in the philosophy of medicine, and a Masters of Science in Philosophy of Psychiatry from King's College London. A native of the Netherlands, Reinier was a visiting Fulbright scholar at New York University and at the University of Pittsburgh. Reinier develops AFCM's educational offerings and collaborates with other organizations to educate the American public about how to advocate for their individual rights in healthcare.Show is Sponsored by The Ayn Rand Institute https://www.aynrand.org/starthereEnergy Talking Points, featuring AlexAI, by Alex Epstein https://alexepstein.substack.com/Express VPN https://www.expressvpn.com/yaronJoin this channel to get access to perks: / @yaronbrook Like what you hear? Like, share, and subscribe to stay updated on new videos and help promote the Yaron Brook Show: https://bit.ly/3ztPxTxSupport the Show and become a sponsor: / yaronbrookshow or https://yaronbrookshow.com/Or make a one-time donation: https://bit.ly/2RZOyJJContinue the discussion by following Yaron on Twitter (https://bit.ly/3iMGl6z) and Facebook (https://bit.ly/3vvWDDC )Want to learn more about Ayn Rand and Objectivism? Visit the Ayn Rand Institute: https://bit.ly/35qoEC3#freemarket #healthcare #Rights #individualism #AynRand #science #philosophyofscience #ethics #selfishness #egoism #capitalism #philosophy #Morality ​ ​#Objectivism​ #politicsBecome a supporter of this podcast: https://www.spreaker.com/podcast/yaron-brook-show--3276901/support.

Join Drs. Stephanie Hartman and Abby Drucker as they discuss the history of medical quackery, pseudoscience and current challenges in today's medical practice with Dr. Lydia Kang. Dr. Kang is an author of young adult fiction, adult fiction and non-fiction, and poetry. She is a practicing physician and Associate Professor of Internal Medicine at Nebraska Medicine who has gained a reputation for helping fellow writers achieve medical accuracy in fiction. Her poetry and non-fiction have been published in JAMA, The Annals of Internal Medicine, Canadian Medical Association Journal, Journal of General Internal Medicine,. The Linden Review, and Flatwater Free Press. She is the co-author of Quackery: A Brief History of the Worst Ways to Cure Everything and the upcoming book, Pseudoscience: An Amusing History of Crackpot Ideas and Why We Love Them.  You can find Dr. Kang at  LydiaKang.com BlueSky: @lydiakang.bsky.social IG: @LydiaKang We invite you to pre-order Pseudoscience: An Amusing History of Crackpot Ideas and Why We Love Them at The Bookworm Omaha. We rely on your donations to keep producing this podcast content and to support physician advocacy in Nebraska. If you would like to support Nebraska Alliance for Physician Advocacy, a 501(c)(3) organization in Nebraska please click to DONATE NOW.  If you have questions or answers, please email us at ⁠contact@nebraskaallianceforphysicianadvocacy.org⁠ Please check out our website at: Nebraska Alliance for Physician Advocacy Instagram Link https://www.instagram.com/neallianceforphysicianadvocacy/ Facebook https://www.facebook.com/neallianceforphysicianadvocacy

We speak with a Partner at an aviation practice who advocates for 737 MAX crash victims. In the news, we look at the Azerbaijan and Jeju crashes, Boeing's safety and quality-control plan update, Delta's plan for an AI-rich future, and V-22 Osprey catastrophic failure risks. Also, favorite flybys from listeners. Guest Erin Applebaum is a partner in the aviation practice at Kreindler & Kreindler LLP, specializing in high-stakes litigation for passengers injured or killed in general aviation accidents and commercial airline disasters.  Erin has devoted her career to advocating for justice and fighting for the advancement of aviation safety. She serves on the Plaintiffs' Executive Committee for the Ethiopian Airlines Flight 302 Boeing 737 MAX litigation. Erin is part of the legal team representing the 737 MAX crash victims in the federal criminal case against Boeing. Erin updates us on the status of the 737 MAX crash civil litigation. The criminal case is ongoing but likely nearing an end. Boeing was found in violation of the deferred prosecution agreement but the judge rejected the negotiated plea deal. The families of the victims are unhappy because the criminal case focuses on the single charge of defrauding the FAA, and not on those who lost their lives. Erin maintains a robust practice of litigating tort claims governed by the Montreal Convention, the global treaty governing international commercial flights. She teaches a popular aviation CLE course for other attorneys on how to litigate personal injury claims for international airline passengers. Erin has published a comprehensive update on the law governing international aviation claims in the highly respected legal journal of McGill University, “Annals of Air and Space Law.”  Erin serves as Co-Chair of the New York City Bar Association's Aeronautics Committee, Vice Chair of the American Bar Association's Aviation and Space Law Committee, and is an active member of the American Association for Justice and the International Aviation Women's Association. Aviation News Russian Air Defence System Caused Azerbaijan Airlines Plane Crash On December 25, 2024, an Azerbaijan Airlines ERJ-190 flying from Baku Azerbaijan to Grozny in Russia's Chechnya crashed in Aktau Kazakhstan leaving 38 people dead. The plane diverted from Grozny due to dense fog and ultimately made an emergency landing an hour later in Grozny. On final approach, the Embraer lost altitude and impacted the ground off the runway. Twenty-nine people, including the cabin crew, survived. Thirty-eight, including the flight crew, did not IATA Statement on Azerbaijan Airlines Flight 8243 says, in part: "Civil aircraft must never be the intended or accidental target of military operations. The strong potential that Azerbaijan Airlines flight 8243 could have been the victim of military operations, as indicated by several governments including Russia and Azerbaijan, places the highest priority on conducting a thorough, transparent, and impartial investigation. The world eagerly awaits the required publication of the interim report within 30 days, in line with international obligations agreed in the Chicago Convention. And should the conclusion be that this tragedy was the responsibility of combatants, the perpetrators must be held accountable and brought to justice." See also: Accident: Azerbaijan E190 near Aktau on Dec 25th 2024, lost height and impacted ground after being shot at EU issues new alert for planes flying in Russian airspace Boeing Shares Details of Safety Plan One Year After Door Plug Incident Boeing provided an update of its plan to address systemic safety and quality-control issues, which included: Reducing 737 fuselage assembly defects at Spirit AeroSystems through increased inspection and a customer quality approval process;  Addressing more than 70% of the action items from employee feedback Managing traveled work at final assembly with "mo...

In this episode, Dr. Sergio Zanotti discusses rational fluid therapy. He is joined by Dr. Adrian Wong, a practicing intensive care medicine and anesthesia physician. Dr. Wong is a consultant and clinical lead at King's College Hospital, London. He also serves as a committee member for the Intensive Care Society FUSIC, examiner for the European Diploma of Intensive Care Medicine, on the executive committee of the International Fluid Academy. Additional resources: Intravenous fluid therapy in the perioperative and critical care setting” Executive summary of the International Fluid Academy (IFA). Malbrain ML, et al. Ann. Intensive Care 2020: https://pubmed.ncbi.nlm.nih.gov/32449147/ Multidisciplinary expert panel report on fluid stewardship: perspectives and practice. Malbrain ML, et al. Annals of Intensive Care 2023: https://pubmed.ncbi.nlm.nih.gov/37747558/ The emerging concept of fluid tolerance: A position paper. Kattan E, et al. Journal of Critical Care 2022: https://pubmed.ncbi.nlm.nih.gov/35660844/ Everything you need to know about derescuscitation. Malbrain ML, et al. Intensive Care Med 2022: https://pubmed.ncbi.nlm.nih.gov/35932335/ Start with Why. TED Talk presented by Simon Sinek: https://simonsinek.com/videos/ted-talks/ Books mentioned in this episode: Thinking Fast and Slow. By Daniel Kahneman: https://amzn.to/4hicUoj Start with Why: How Great Leaders Inspire Everybody to Take Action. By Simon Sinek: https://bit.ly/42hzt8n

In this edition of Titans of Science, Chris Smith chats with co-founder of Annals of Improbable Research, and the master of ceremonies for the Ig Nobel prize, Marc Abrahams... Like this podcast? Please help us by supporting the Naked Scientists

In most of the U.S., cities are for singles, roommates, and childless couples, and the suburbs are for raising kids. That's not true of much of the rest of the world, and perhaps the nearest example of family-friendly urbanism can be found just a few miles to the north, in Vancouver, British Columbia. Vancouver's under-15 population fell by one percent citywide between 1996 and 2016, but in downtown specifically, its youth population nearly tripled. Louis Thomas, lecturer at Georgetown University and a parent himself, joins us this week to discuss the history, policies, and social infrastructure that have enabled this incredible shift, and how those lessons might translate to other cities and urban cores across North America.Show notes:Thomas, L. L. (2021). Committed and “Won Over” Parents in Vancouver's Dense Family-Oriented Urbanism. Journal of the American Planning Association, 87(2), 239-253.Karsten, L. (2015). Middle-class childhood and parenting culture in high-rise Hong Kong: On scheduled lives, the school trap and a new urban idyll. Children's Geographies, 13(5), 556-570.Karsten, L. (2015). Middle-class households with children on vertical family living in Hong Kong. Habitat International, 47, 241-247.Yuen, B., Yeh, A., Appold, S. J., Earl, G., Ting, J., & Kurnianingrum Kwee, L. (2006). High-rise living in Singapore public housing. Urban Studies, 43(3), 583-600.Thomas, L. L. (2020). From childless tower to child-full density: families and the evolution of vancouverism. Planning Perspectives, 1-23.Ley, D. (1980). Liberal ideology and the postindustrial city. Annals of the Association of American geographers, 70(2), 238-258.City of Vancouver Planning Department. (1978). Housing Families at High Densities.Fishman, R. (2008). Bourgeois utopias: The rise and fall of suburbia. Basic books.

In this episode of The Brave Enough Show, Dr. Sasha Shillcutt and Dr. Lydia Kang discuss: Dr. Lydia Kang's journey as an author and how she balances her writing with her work as a physician. They talk about how to receive negative feedback and how rejection can be a stepping stool to deep growth. In this episode, they touch on:  How to filter feedback to assure it is useful to you  How to craft criticism in a way that people respond and grow from it  The beauty of sharing your rejections and failures with another person     “When you put yourself in big places and try bigger things, you are going to experience more failure and rejection. It is normal and more common that people understand in our shiny world of posting all the positive things on social media.” Dr. Lydia Kang    Dr. Lydia Kang is an author of young adult fiction, adult fiction and non-fiction, and poetry. She graduated from Columbia University and New York University School of Medicine, completing her residency and chief residency at Bellevue Hospital in New York City. She is a practicing physician and associate professor of Internal Medicine who has gained a reputation for helping fellow writers achieve medical accuracy in fiction. Her poetry and non-fiction have been published in JAMA, The Annals of Internal Medicine, Canadian Medical Association Journal, Journal of General Internal Medicine, and Great Weather for Media. She believes in science and knocking on wood, and currently lives in Omaha with her husband and three children.    Follow Dr. Lydia Kang Instagram  Website  facebook  Books    Episode Links:  REVIVE Retreat Brave Ballance   Follow Brave Enough:   WEBSITE | INSTAGRAM | FACEBOOK | TWITTER | LINKEDIN Join The Table, Brave Enough's community. The ONLY professional membership group that meets both the professional and personal needs of high-achieving women.

Contributor: Travis Barlock MD Educational Pearls: What is the ST segment? The ST segment on an ECG represents the interval between the end of ventricular depolarization (QRS) and the beginning of ventricular repolarization (T-wave).  It should appear isoelectric (flat) in a normal ECG. What if the ST segment is elevated? This is evidence that there is an injury that goes all the way through the muscular wall of the heart (transmural) This is very concerning for a heart attack (STEMI) but can be occasionally caused by other pathology, such as pericarditis What if the ST segment is depressed? This is evidence that only the innermost part of the muscular wall of the heart is becoming ischemic This has a much broader differential and includes a partial occlusion of a coronary artery but also any other stress on the body that could cause a supply-and-demand mismatch between the oxygen the coronaries can deliver and the oxygen the heart needs This is called subendocardial ischemia What else should you look for in the ECG to identify subendocardial ischemia? The ST-depressions should be at least 1 mm The ST depressions should be present in leads I, II, V4-6 and a variable number of additional leads. There is often reciprocal ST elevation in aVR > 1 mm The most important thing to remember when you see subendocardial ischemia is…history Still, keep all cardiac causes on your differential, such as unstable angina, stable angina, Prinzmetal angina, etc. Also consider a wide array of non-cardiac causes such as severe anemia, severe hypertension, pulmonary embolism, COPD, severe pneumonia, sepsis, shock, thyrotoxicosis, stimulant use, DKA, or any other state that lead to reduced oxygen supply to the subendocardium and/or increased myocardial oxygen demand. References Birnbaum, Y., Wilson, J. M., Fiol, M., de Luna, A. B., Eskola, M., & Nikus, K. (2014). ECG diagnosis and classification of acute coronary syndromes. Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 19(1), 4–14. https://doi.org/10.1111/anec.12130 Buttà, C., Zappia, L., Laterra, G., & Roberto, M. (2020). Diagnostic and prognostic role of electrocardiogram in acute myocarditis: A comprehensive review. Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 25(3), e12726. https://doi.org/10.1111/anec.12726 Cadogan, E. B. a. M. (2024, October 8). Myocardial Ischaemia. Life in the Fast Lane • LITFL. Retrieved December 7, 2024, from https://litfl.com/myocardial-ischaemia-ecg-library/#:~:text=ST%20depression%20due%20to%20subendocardial,left%20main%20coronary%20artery%20occlusion. Summarized by Jeffrey Olson, MS3 | Edited by Meg Joyce & Jorge Chalit, OMS3 Donate: https://emergencymedicalminute.org/donate/  

The Ig Nobel awards are a salute to achievements that, in the words of the organizers, “make people laugh, then think.”  Each year, the editors of the science humor magazine Annals of Improbable Research choose 10 lucky(?) winners who have unusual achievements in science, medicine, and other fields. This year's awards were presented in a theatrical extravaganza in an MIT lecture hall in September.They included awards for studying coin flipping (including hundreds of thousands of real coin flips), the movements of a dead trout, and an opera about Murphy's Law. In a Science Friday holiday tradition, Ira hosts an hour of highlights from the ceremony.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.