Podcasts about Annals

Why are we still treating acute uncomplicated diverticulitis with antibiotics? There is plenty of evidence from several randomized controlled trials demonstrating that symptomatic management alone yields similar results. If we should continue prescribing antibiotics for acute uncomplicated diverticulitis, which patients should undergo treatment and when? Join Drs. Jared Hendren, Elissa Dabaghi, Joseph Trunzo, Ajaratu Keshinro, and David Rosen as they discuss the management of uncomplicated diverticulitis while reviewing groundbreaking literature. Hosts: -Jared Hendren, MD Institution: Department of General Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio - Elissa Dabaghi, MD Institution: Department of General Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio - Joseph Trunzo, MD Institution: Department of Colon and Rectal Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio Social Media Handle: X/Twitter @joseph_trunzo - Ajaratu Keshinro, MD Institution: Department of Colon and Rectal Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio Social Media Handle: X/Twitter- @AJKesh - David Rosen, MD Institution: Department of Colon and Rectal Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio Social Media Handle: X/Twitter- @davidrrosenmd Learning Objectives: By the end of this episode, listeners will be able to: 1.     Identify criteria for managing acute uncomplicated diverticulitis without antibiotics based on recent literature 2.     Define uncomplicated and complicated diverticulitis 3.     Discuss nuanced management decisions of patients with uncomplicated diverticulitis to determine when antibiotics may be appropriate for management References: 1.     Azhar, N., Aref, H., Brorsson, A., Lydrup, M.‑L., Jörgren, F., Schultz, J. K., & Buchwald, P. (2022). Management of acute uncomplicated diverticulitis without antibiotics: Compliance and outcomes – a retrospective cohort study. BMC Emergency Medicine, 22(1), Article 28. https://doi.org/10.1186/s12873‑022‑00584‑X  2.     Mora‑López, L., Ruiz‑Edo, N., Estrada‑Ferrer, O., Piñana‑Campón, M. L., Labró‑Ciurans, M., Escuder‑Perez, J., Sales‑Mallafré, R., Rebasa‑Cladera, P., Navarro‑Soto, S., Serra‑Aracil, X., & DINAMO‑study Group. (2021). Efficacy and safety of nonantibiotic outpatient treatment in mild acute diverticulitis (DINAMO‑study): A multicentre, randomised, open‑label, noninferiority trial. Annals of Surgery, 274(5), e435–e442. https://doi.org/10.1097/SLA.0000000000005031 3.     Daniels, L., Ünlü, Ç., de Korte, N., van Dieren, S., Stockmann, H. B., Vrouenraets, B. C., Consten, E. C., van der Hoeven, J. A., Eijsbouts, Q. A., Faneyte, I. F., Bemelman, W. A., Dijkgraaf, M. G., & Boermeester, M. A. (2017). Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT‑proven uncomplicated acute diverticulitis. British Journal of Surgery, 104(1), 52‑61. https://doi.org/10.1002/bjs.10309 4.     Chabok, A., Påhlman, L., Hjern, F., Haapaniemi, S., & Smedh, K.; AVOD Study Group. (2012). Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis. British Journal of Surgery, 99(4), 532–539. https://doi.org/10.1002/bjs.8688 Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listen Behind the Knife Premium: General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-review Trauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlas Dominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkship Dominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotation Vascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-review Colorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-review Surgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-review Cardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-review Download our App: Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049 Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

Dr. Centor revisits information included in the Annals of Internal Medicine supplement "What You May Have Missed in 2024."

Indolent Systemic Mastocytosis (ISM) is a rare but often underrecognized clonal mast cell disorder. From random hives to gut pain and brain fog, ISM can feel like a medical mystery. We continue our review of “Management of indolent mastocytosis and mast cell activation syndrome - A clinical yardstick,” published in June 2025 in The Annals of Allergy, Asthma & Immunology. This is Part 2 of our discussion, with a focus on indolent systemic mastocytosis. We look at what causes it, how it's diagnosed, and how to manage symptoms and improve quality of life. In this episode, we break down this complex mast cell disease and how doctors use baseline serum tryptase, KIT D816V testing, and HaT screening to find answers. Plus, we explain how treatments like antihistamines, mast cell stabilizers, and avapritinib can help people live better with ISM.

In this episode Hecate discusses why menstruation can be triggering for survivors, especially for those who have been assaulted during their periods. Hecate provides statistics from medical studies indicating that a significant percentage of SA survivors were menstruating at the time of their assault. The combined social stigmas against speaking about SA and menstruation mean this is an experience that is not being talked about enough, leading to even greater feelings of isolation and shame. The episode also addresses some of the challenges of managing periods post-trauma, and different menstrual products through a survivor's lens. With personal anecdotes and research-backed insights, this episode aims to provide a voice to the often unspoken and overlooked intersection of menstruation and SA trauma. Hecate hopes this episode will help other survivors who have had this experience feel less alone.Tw/Cw: SA (and some details of assaults), R*pe, PTSD, menstruation, substances, and strong language.Links and References:Cardenas, K., Wiersma, G., Dykema, J., Rossman, L., Fedewa, J., & Jones, J. S. (2011). 279 impact of the victim's menstrual cycle phase on genital injuries following sexual assault. Annals of Emergency Medicine, 58(4). https://doi.org/10.1016/j.annemergmed.2011.06.309 Gollapudi, M., Thomas, A., Yogarajah, A., Ospina, D., Daher, J. C., Rahman, A., Santistevan, L., Patel, R. V., Abraham, J., Oommen, S. G., & Siddiqui, H. F. (2024). Understanding the interplay between premenstrual dysphoric disorder (PMDD) and female sexual dysfunction (FSD). Cureus, 16(6). https://doi.org/10.7759/cureus.62788 Noll, J. G., Trickett, P. K., Long, J. D., Negriff, S., Susman, E. J., Shalev, I., Li, J. C., & Putnam, F. W. (2017). Childhood sexual abuse and early timing of puberty. Journal of Adolescent Health, 60(1), 65–71. https://doi.org/10.1016/j.jadohealth.2016.09.008 Vu, A., Moaddel, V., Emmerich, B., Rossman, L., Bach, J., Seamon, J., Barnes, M., Ouellette, L., & Jones, J. (2023). Association between the victim's menstrual cycle phase and genital injuries following sexual assault. Clinical Journal of Obstetrics and Gynecology, 6(2), 038–042. https://doi.org/10.29328/journal.cjog.1001127 *Thank you again to my sister Chie for their invaluable help with research and citations!*Articles about the heavy metals found in tampons: https://factor.niehs.nih.gov/2024/8/feature/3-feature-metals-in-tamponshttps://publichealth.berkeley.edu/articles/spotlight/research/first-study-to-measure-toxic-metals-in-tampons-shows-arsenic-and-leadhttps://www.sciencedirect.com/science/article/pii/S0160412024004355#:~:text=Across%20those%20studies%2C%20a%20range,et%20al.%2C%202022).Lucky Iron Fish: https://luckyironlife.com/?srsltid=AfmBOorbSgfTM6sE3c6r-IRy3MNC0u-i8v-S4-s5lkZPo89aSCXJvEfjFinding OK: https://www.finding-ok.com/Hecate's Links: https://linktr.ee/FindingOK Support the Podcast and become a Patreon member!https://www.patreon.com/c/HecateFindingOKFinding OK is funded entirely by generosity of listeners like you!https://www.finding-ok.com/support/Music is "Your Heart is a Muscle the Size of Your Fist" used with the personal permission of Ramshackle Glory. Go check out their music!https://open.spotify.com/artist/0qdbl...Timestamps:00:00 Introduction and Trigger Warnings01:17 Menstruation and Trauma07:47 Challenges with Sanitary Products12:14 Personal Experiences of Assault During Menstruation15:58 Statistics and Research on Assault During Menstruation21:01 Triggers and Coping Mechanisms32:08 Conclusion and Support3Support the show

In the August issue of the Annals of Emergency Medicine podcast, Ryan and Rory discuss point-of-care high sensitivity troponins, intubation practices in community emergency medicine and much more.

All over the world, for all of human history – and probably going back to our earliest hominid ancestors – people have found ways to try to keep themselves clean. But how did soap come about? Research: “Soap, N. (1), Etymology.” Oxford English Dictionary, Oxford UP, June 2025, https://doi.org/10.1093/OED/1115187665. American Cleaning Institute. “Soaps & Detergents History.” https://www.cleaninginstitute.org/understanding-products/why-clean/soaps-detergents-history Beckmann, John. “History of Inventions, Discoveries and Origins.” William Johnston, translator. Bosart, L.W. “The Early History of the Soap Industry.” The American Oil Chemists' Society. Journal of Oil & Fat Industries 1924-10: Vol 1 Iss 2. Cassidy, Cody. “Who Discovered Soap? What to Know About the Origins of the Life-Saving Substance.” Time. 5/5/2020. https://time.com/5831828/soap-origins/ Ciftyurek, Muge, and Kasim Ince. "Selahattin Okten Soap Factory in Antakya and an Evaluation on Soap Factory Plan Typology/Antakya'da Bulunan Selahattin Okten Sabunhanesi ve Sabunhane Plan Tipolojisi Uzerine Bir Degerlendirme." Art-Sanat, no. 19, Jan. 2023, pp. 133+. Gale Academic OneFile, dx.doi.org/10.26650/artsanat.2023.19.1106544. Accessed 18 Aug. 2025. Costa, Albert B. “Michel-Eugène Chevreul.” Encyclopedia Britannica. https://www.britannica.com/biography/Michel-Eugene-Chevreul Curtis, Valerie A. “Dirt, disgust and disease: a natural history of hygiene.” Journal of epidemiology and community health vol. 61,8 (2007): 660-4. doi:10.1136/jech.2007.062380 Dijkstra, Albert J. “How Chevreul (1786-1889) based his conclusions on his analytical results.” OCL. Vol. 16, No. 1. January-February 2009. Gibbs, F.W. “The History and Manufacture of Soap.” Annals of Science. 1939. Koeppel, Dan. “The History of Soap.” 4/15/2020. https://www.nytimes.com/wirecutter/blog/history-of-soap/ List, Gary, and Michael Jackson. “Giants of the Past: The Battle Over Hydrogenation (1903-1920).” https://www.ars.usda.gov/research/publications/publication/?seqNo115=210614 Maniatis, George C. “Guild Organized Soap Manufacturing Industry in Constantinople: Tenth-Twelfth Centuries.” Byzantion, 2010, Vol. 80 (2010). https://www.jstor.org/stable/44173107 National Museum of American History. “Bathing (Body Soaps and Cleansers).” https://americanhistory.si.edu/collections/object-groups/health-hygiene-and-beauty/bathing-body-soaps-and-cleansers New Mexico Historic Sites. “Making Soap from the Leaves of the Soaptree Yucca.” https://nmhistoricsites.org/assets/files/selden/Virtual%20Classroom_Soaptree%20Yucca%20Soap%20Making.pdf “The history of soapmaking.” 8/30/2019. https://www.open.edu/openlearn/history-the-arts/history/history-science-technology-and-medicine/history-science/the-history-soapmaking Pliny the Elder. “The Natural History of Pliny. Translated, With Copious Notes and Illustrations.” Vol. 5. John Bostock, translator. https://www.gutenberg.org/files/60688/60688-h/60688-h.htm Pointer, Sally. “An Experimental Exploration of the Earliest Soapmaking.” EXARC Journal. 2024/3. 8/22/2024. https://exarc.net/issue-2024-3/at/experimental-exploration-earliest-soapmaking Ridner, Judith. “The dirty history of soap.” The Conversation. 5/12/2020. https://theconversation.com/the-dirty-history-of-soap-136434 Routh, Hirak Behari et al. “Soaps: From the Phoenicians to the 20th Century - A Historical Review.” Clinics in Dermatology. Vol. No. 3. 1996. Smith, Cyril Stanley, and John G. Hawthorne. “Mappae Clavicula: A Little Key to the World of Medieval Techniques.” Transactions of the American Philosophical Society, vol. 64, no. 4, 1974, pp. 1–128. JSTOR, https://doi.org/10.2307/1006317. Accessed 18 Aug. 2025. Timilsena, Yakindra Prasad et al. “Perspectives on Saponins: Food Functionality and Applications.” International journal of molecular sciences vol. 24,17 13538. 31 Aug. 2023, doi:10.3390/ijms241713538 “Craftsmanship of Aleppo Ghar soap.” https://ich.unesco.org/en/RL/craftsmanship-of-aleppo-ghar-soap-02132 “Tradition of Nabulsi soap making in Palestine.” https://ich.unesco.org/en/RL/tradition-of-nabulsi-soap-making-in-palestine-02112 “Soaps.” https://www.fs.usda.gov/wildflowers/ethnobotany/soaps.shtml van Dijk, Kees. “Soap is the onset of civilization.” From Cleanliness and Culture. Kees van Dijk and Jean Gelman Taylor, eds. Brill. 2011. https://www.jstor.org/stable/10.1163/j.ctvbnm4n9.4 Wei, Huang. “The Sordid, Sudsy Rise of Soap in China.” Sixth Tone. 8/11/2020. https://www.sixthtone.com/news/1006041 See omnystudio.com/listener for privacy information.

Send us a message with this link, we would love to hear from you. Standard message rates may apply.The flu vaccine is our best defense against influenza, a contagious respiratory virus that causes millions of illnesses and thousands of deaths in the US each year. Despite being only 40-60% effective, the vaccine significantly reduces hospitalizations, outpatient visits, and deaths while protecting vulnerable populations who cannot be vaccinated.• Influenza causes 9-41 million illnesses, 140,000-960,000 hospitalizations, and 12,000-80,000 deaths annually in the US• Everyone aged six months and older should receive the flu vaccine yearly• The vaccine must be updated annually because the flu virus changes each year• Getting vaccinated helps protect vulnerable populations like infants and immunocompromised individuals• Common misconception that the vaccine causes flu is false – it cannot give you the flu• Only 40-46% of Americans get the flu vaccine annually despite its proven benefits• The best time to get vaccinated is before flu season begins, but getting it later still helps• Flu vaccination reduces strain on hospitals during peak seasonsGo get your flu shot today! It's the best way to protect yourself, your loved ones, and your neighbors ReferencesPrevention and Control of Seasonal Influenza With Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2022-23 Influenza Season. Grohskopf LA, Blanton LH, Ferdinands JM, et al. MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports. 2022;71(1):1-28. doi:10.15585/mmwr.rr7101a1. Copyright License: CC0.Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa. Uyeki TM, Bernstein HH, Bradley JS, et al. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 2019;68(6):e1-e47. doi:10.1093/cid/ciy866.Influenza Vaccination. Treanor JJ. The New England Journal of Medicine. 2016;375(13):1261-8. doi:10.1056/NEJMcp1512870.Effects of Influenza Vaccination in the United States During the 2017-2018 Influenza Season. Rolfes MA, Flannery B, Chung JR, et al. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 2019;69(11):1845-1853. doi:10.1093/cid/ciz075.Vaccines for Preventing Influenza in Healthy Adults. Demicheli V, Jefferson T, Ferroni E, Rivetti A, Di Pietrantonj C. The Cochrane Database of Systematic Reviews. 2018;2:CD001269. doi:10.1002/14651858.CD001269.pub6.Recommendations for Prevention and Control of Influenza in Children, 2022-2023. Pediatrics. 2022;150(4):e2022059275. doi:10.1542/peds.2022-059275.Influenza. Uyeki TM. Annals of Internal Medicine. 2021;174(11):ITC161-ITC176. doi:10.7326/AITC202111160.Support the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski

En este episodio exploramos a fondo el mutismo acinético, una de las manifestaciones más desconcertantes tras un daño cerebral grave. Hablamos de su base neurofisiológica, su relación con el sistema dopaminérgico y los circuitos prefronto-subcorticales, y cómo se diferencia clínicamente de otros estados de conciencia alterada. Recorremos también las opciones terapéuticas más prometedoras, desde la estimulación multisensorial y la verticalización robótica hasta técnicas de neuromodulación como la estimulación cerebral profunda, la estimulación medular o la tDCS. Un episodio técnico, narrativo y lleno de preguntas clínicas clave, pensado para quienes trabajan día a día con pacientes que aún no responden... pero que podrían hacerlo. Referencias del episodio: 1. Arnts, H., van Erp, W. S., Lavrijsen, J. C. M., van Gaal, S., Groenewegen, H. J., & van den Munckhof, P. (2020). On the pathophysiology and treatment of akinetic mutism. 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Scientific reports, 14(1), 2950. https://doi.org/10.1038/s41598-024-52267-1 (https://pubmed.ncbi.nlm.nih.gov/38316863/). 4. Bai, Y., Xia, X., Li, X., Wang, Y., Yang, Y., Liu, Y., Liang, Z., & He, J. (2017). Spinal cord stimulation modulates frontal delta and gamma in patients of minimally consciousness state. Neuroscience, 346, 247–254. https://doi.org/10.1016/j.neuroscience.2017.01.036 (https://pubmed.ncbi.nlm.nih.gov/28147246/). 5. Bai, Y., Xia, X., Liang, Z., Wang, Y., Yang, Y., He, J., & Li, X. (2017). Corrigendum: Frontal Connectivity in EEG Gamma (30-45 Hz) Respond to Spinal Cord Stimulation in Minimally Conscious State Patients. Frontiers in cellular neuroscience, 11, 251. https://doi.org/10.3389/fncel.2017.00251 (https://pubmed.ncbi.nlm.nih.gov/28828002/). 6. Bai, Y., Lin, Y., & Ziemann, U. (2021). Managing disorders of consciousness: the role of electroencephalography. Journal of neurology, 268(11), 4033–4065. https://doi.org/10.1007/s00415-020-10095-z (https://pubmed.ncbi.nlm.nih.gov/32915309/). 7. Cairns, H., Oldfield, R. C., Pennybacker, J. B., & Whitteridge, D. (1941). Akinetic mutism with an epidermoid cyst of the 3rd ventricle. Brain, 64(4), 273–290 (https://academic.oup.com/brain/article-abstract/64/4/273/332088?redirectedFrom=fulltext). 8. Chen, Q., Huang, W., Tang, J., Ye, G., Meng, H., Jiang, Q., Ge, L., Li, H., Liu, L., Jiang, Q., & Wang, D. (2025). Reviving consciousness: The impact of short-term spinal cord stimulation on patients with early-onset prolonged disorders of consciousness. Journal of Neurorestoratology, 13(1), 100143. https://doi.org/10.1016/j.jnrt.2024.100143 (https://www.sciencedirect.com/science/article/pii/S2324242624000500?via%3Dihub). 9. Clavo, B., Robaina, F., Montz, R., Carames, M. A., Otermin, E., & Carreras, J. L. (2008). Effect of cervical spinal cord stimulation on cerebral glucose metabolism. Neurological research, 30(6), 652–654. https://doi.org/10.1179/174313208X305373 (https://pubmed.ncbi.nlm.nih.gov/18513465/). 10. Corazzol, M., Lio, G., Lefevre, A., Deiana, G., Tell, L., André-Obadia, N., Bourdillon, P., Guenot, M., Desmurget, M., Luauté, J., & Sirigu, A. (2017). Restoring consciousness with vagus nerve stimulation. Current biology : CB, 27(18), R994–R996. https://doi.org/10.1016/j.cub.2017.07.060 (https://pubmed.ncbi.nlm.nih.gov/28950091/). 11. Della Pepa, G. M., Fukaya, C., La Rocca, G., Zhong, J., & Visocchi, M. (2013). Neuromodulation of vegetative state through spinal cord stimulation: where are we now and where are we going?. Stereotactic and functional neurosurgery, 91(5), 275–287. https://doi.org/10.1159/000348271 (https://pubmed.ncbi.nlm.nih.gov/23797266/). 12. De Luca, R., Bonanno, M., Vermiglio, G., Trombetta, G., Andidero, E., Caminiti, A., Pollicino, P., Rifici, C., & Calabrò, R. S. (2022). Robotic Verticalization plus Music Therapy in Chronic Disorders of Consciousness: Promising Results from a Pilot Study. Brain sciences, 12(8), 1045. https://doi.org/10.3390/brainsci12081045 (https://pubmed.ncbi.nlm.nih.gov/36009107/). 13. Dong, X., Tang, Y., Zhou, Y., & Feng, Z. (2023). Stimulation of vagus nerve for patients with disorders of consciousness: a systematic review. Frontiers in neuroscience, 17, 1257378. https://doi.org/10.3389/fnins.2023.1257378 (https://pubmed.ncbi.nlm.nih.gov/37781261/). 14. Fan, W., Fan, Y., Liao, Z., & Yin, Y. (2023). Effect of Transcranial Direct Current Stimulation on Patients With Disorders of Consciousness: A Systematic Review and Meta-analysis. American journal of physical medicine & rehabilitation, 102(12), 1102–1110. https://doi.org/10.1097/PHM.0000000000002290 (https://pubmed.ncbi.nlm.nih.gov/37205736/). 15. Frazzitta, G., Zivi, I., Valsecchi, R., Bonini, S., Maffia, S., Molatore, K., Sebastianelli, L., Zarucchi, A., Matteri, D., Ercoli, G., Maestri, R., & Saltuari, L. (2016). Effectiveness of a Very Early Stepping Verticalization Protocol in Severe Acquired Brain Injured Patients: A Randomized Pilot Study in ICU. PloS one, 11(7), e0158030. https://doi.org/10.1371/journal.pone.0158030 (https://pubmed.ncbi.nlm.nih.gov/27447483/). 16. Jang, S. H., & Byun, D. H. (2022). A Review of Studies on the Role of Diffusion Tensor Magnetic Resonance Imaging Tractography in the Evaluation of the Fronto-Subcortical Circuit in Patients with Akinetic Mutism. Medical science monitor : international medical journal of experimental and clinical research, 28, e936251. https://doi.org/10.12659/MSM.936251 (https://pubmed.ncbi.nlm.nih.gov/35181647/). 17. Lombardi, F., Taricco, M., De Tanti, A., Telaro, E., & Liberati, A. (2002). Sensory stimulation for brain injured individuals in coma or vegetative state. The Cochrane database of systematic reviews, 2002(2), CD001427. https://doi.org/10.1002/14651858.CD001427 (https://pmc.ncbi.nlm.nih.gov/articles/PMC7045727/). 18. Magee, W. L., & O'Kelly, J. (2015). Music therapy with disorders of consciousness: current evidence and emergent evidence-based practice. Annals of the New York Academy of Sciences, 1337, 256–262. https://doi.org/10.1111/nyas.12633 (https://pubmed.ncbi.nlm.nih.gov/25773642/). 19. Mateo-Sierra, O., Gutiérrez, F.A., Fernández-Carballal, C., Pinilla, D., Mosqueira, B., Iza, B., & Carrillo, R.. (2005). Mutismo acinético relacionado con hidrocefalia y cirugía cerebelosa tratado con bromocriptina y efedrina: revisión fisiopatológica. Neurocirugía, 16(2), 134-141. (https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-14732005000200005). 20. Noé, E., Ferri, J., Colomer, C., Moliner, B., O'Valle, M., Ugart, P., Rodriguez, C., & Llorens, R. (2020). Feasibility, safety and efficacy of transauricular vagus nerve stimulation in a cohort of patients with disorders of consciousness. Brain stimulation, 13(2), 427–429. https://doi.org/10.1016/j.brs.2019.12.005 (https://pubmed.ncbi.nlm.nih.gov/31866491/). 21. Norwood, M. F., Lakhani, A., Watling, D. P., Marsh, C. H., & Zeeman, H. (2023). Efficacy of Multimodal Sensory Therapy in Adult Acquired Brain Injury: A Systematic Review. Neuropsychology review, 33(4), 693–713. https://doi.org/10.1007/s11065-022-09560-5 (https://pubmed.ncbi.nlm.nih.gov/36056243/). 22. O'Neal, C. M., Schroeder, L. N., Wells, A. A., Chen, S., Stephens, T. M., Glenn, C. A., & Conner, A. K. (2021). Patient Outcomes in Disorders of Consciousness Following Transcranial Magnetic Stimulation: A Systematic Review and Meta-Analysis of Individual Patient Data. Frontiers in neurology, 12, 694970. https://doi.org/10.3389/fneur.2021.694970 (https://pubmed.ncbi.nlm.nih.gov/34475848/). 23. Schiff, N. D., Giacino, J. T., Kalmar, K., Victor, J. D., Baker, K., Gerber, M., Fritz, B., Eisenberg, B., Biondi, T., O'Connor, J., Kobylarz, E. J., Farris, S., Machado, A., McCagg, C., Plum, F., Fins, J. J., & Rezai, A. R. (2007). Behavioural improvements with thalamic stimulation after severe traumatic brain injury. Nature, 448(7153), 600–603. https://doi.org/10.1038/nature06041 (https://pubmed.ncbi.nlm.nih.gov/17671503/). 24. Schiff N. D. (2016). Central thalamic deep brain stimulation to support anterior forebrain mesocircuit function in the severely injured brain. Journal of neural transmission (Vienna, Austria : 1996), 123(7), 797–806. https://doi.org/10.1007/s00702-016-1547-0 (https://pubmed.ncbi.nlm.nih.gov/27113938/). 25. Schiff N. D. (2023). Mesocircuit mechanisms in the diagnosis and treatment of disorders of consciousness. Presse medicale (Paris, France : 1983), 52(2), 104161. https://doi.org/10.1016/j.lpm.2022.104161 (https://pubmed.ncbi.nlm.nih.gov/36563999/). 26. Shimojo, S., & Shams, L. (2001). Sensory modalities are not separate modalities: plasticity and interactions. Current opinion in neurobiology, 11(4), 505–509. https://doi.org/10.1016/s0959-4388(00)00241-5 (https://pubmed.ncbi.nlm.nih.gov/11502399/). 27. Stephens, T. M., Young, I. M., O'Neal, C. M., Dadario, N. B., Briggs, R. G., Teo, C., & Sughrue, M. E. (2021). Akinetic mutism reversed by inferior parietal lobule repetitive theta burst stimulation: Can we restore default mode network function for therapeutic benefit?. Brain and behavior, 11(8), e02180. https://doi.org/10.1002/brb3.2180 (https://pubmed.ncbi.nlm.nih.gov/34145791/). 28. Piedade, G. S., Assumpcao de Monaco, B., Guest, J. D., & Cordeiro, J. G. (2023). Review of spinal cord stimulation for disorders of consciousness. Current opinion in neurology, 36(6), 507–515. https://doi.org/10.1097/WCO.0000000000001222 (https://pubmed.ncbi.nlm.nih.gov/37889524/). 29. Rosenfelder, M. J., Helmschrott, V. C., Willacker, L., Einhäupl, B., Raiser, T. M., & Bender, A. (2023). Effect of robotic tilt table verticalization on recovery in patients with disorders of consciousness: a randomized controlled trial. Journal of neurology, 270(3), 1721–1734. https://doi.org/10.1007/s00415-022-11508-x (https://pubmed.ncbi.nlm.nih.gov/36536249/). 30. Thibaut, A., Bruno, M. A., Ledoux, D., Demertzi, A., & Laureys, S. (2014). tDCS in patients with disorders of consciousness: sham-controlled randomized double-blind study. Neurology, 82(13), 1112–1118. https://doi.org/10.1212/WNL.0000000000000260 (https://pubmed.ncbi.nlm.nih.gov/24574549/). 31. Visocchi, M., Della Pepa, G. M., Esposito, G., Tufo, T., Zhang, W., Li, S., & Zhong, J. (2011). Spinal cord stimulation and cerebral hemodynamics: updated mechanism and therapeutic implications. Stereotactic and functional neurosurgery, 89(5), 263–274. https://doi.org/10.1159/000329357 (https://pubmed.ncbi.nlm.nih.gov/21860253/). 32. Yang, Y., He, Q., Xia, X., Dang, Y., Chen, X., He, J., & Zhao, J. (2022). Long-term functional prognosis and related factors of spinal cord stimulation in patients with disorders of consciousness. CNS neuroscience & therapeutics, 28(8), 1249–1258. https://doi.org/10.1111/cns.13870 (https://pubmed.ncbi.nlm.nih.gov/35619213/). 33. Yang, Y., He, Q., Dang, Y., Xia, X., Xu, X., Chen, X., Zhao, J., & He, J. (2023). Long-term functional outcomes improved with deep brain stimulation in patients with disorders of consciousness. Stroke and vascular neurology, 8(5), 368–378. https://doi.org/10.1136/svn-2022-001998 (https://pubmed.ncbi.nlm.nih.gov/36882201/). 34. Yu, Y. T., Yang, Y., Wang, L. B., Fang, J. L., Chen, Y. Y., He, J. H., & Rong, P. J. (2017). Transcutaneous auricular vagus nerve stimulation in disorders of consciousness monitored by fMRI: The first case report. Brain stimulation, 10(2), 328–330. https://doi.org/10.1016/j.brs.2016.12.004 (https://pubmed.ncbi.nlm.nih.gov/28017322/). 35. Zhou, Y. F., Kang, J. W., Xiong, Q., Feng, Z., & Dong, X. Y. (2023). Transauricular vagus nerve stimulation for patients with disorders of consciousness: A randomized controlled clinical trial. Frontiers in neurology, 14, 1133893. https://doi.org/10.3389/fneur.2023.1133893 (https://pubmed.ncbi.nlm.nih.gov/36937511/). 36. Zhuang, Y., Yang, Y., Xu, L., Chen, X., Geng, X., Zhao, J., & He, J. (2022). Effects of short-term spinal cord stimulation on patients with prolonged disorder of consciousness: A pilot study. Frontiers in neurology, 13, 1026221. https://doi.org/10.3389/fneur.2022.1026221 (https://pubmed.ncbi.nlm.nih.gov/36313512/). 37. Zuo, J., Tao, Y., Liu, M., Feng, L., Yang, Y., & Liao, L. (2021). The effect of family-centered sensory and affective stimulation on comatose patients with traumatic brain injury: A systematic review and meta-analysis. International journal of nursing studies, 115, 103846. https://doi.org/10.1016/j.ijnurstu.2020.103846 (https://pubmed.ncbi.nlm.nih.gov/33485101/).

The United Nations declared 2025 as the International Year of Glaciers' Preservation and proclaimed 21 March the annual World Day for Glaciers. Related initiatives are highlighting the importance of glaciers worldwide, including their role in freshwater supplies and sea level rise, and the increasing threats of glacial hazards, while illustrating the impacts of climate change on the critical role that glaciers play in our Earth's systems. Professor Hester Jiskoot will present the trends and future projections in receding glaciers and ice sheets worldwide and the related implications for humanity. Examples of vanishing glaciers will be exposed, as well as ways to slow down the melt and to ultimately preserve glaciers. She will also speak to the sheer beauty of the cryosphere and the importance of snow and ice for the Canadian identity, all while mourning several iconic Canadian glaciers that are now drowning in their own tears. The presentation will be richly illustrated with photos. Speaker: Dr. Hester Jiskoot Dr. Hester Jiskoot is Professor of Physical Geography & Glaciology in the Department of Geography and Environment at the University of Lethbridge. With a BSc and MSc from the University of Amsterdam (Netherlands) and a PhD from the University of Leeds (UK), her main research interests are in glacier-climate-landscape interactions, with an emphasis on ice flow dynamics and glacier edge effects. Since 1991, Prof. Jiskoot has been a member and leader of glaciological expeditions to Arctic and Alpine regions, while in 2019 she sailed the Northwest Passage on a historic ketch. At the University of Lethbridge, Professor Jiskoot leads the Glaciology and Geoscience Lab and teaches courses in physical geography and the geosciences. She has been funded broadly, is well- published and collaborates with glaciologists worldwide. Currently Chief Editor of the International Glaciological Society's scientific publications Journal of Glaciology and Annals of Glaciology, Prof. Jiskoot has previously been in various executive functions of national geographical associations. Prof. Jiskoot is a Fellow of the Royal Canadian Geographical Society.

In the second episode of this new collaboration between BTK and Annals of surgery, we discuss another hot topic: academic surgery. Specifically, we discuss dedicated research time for residents and how surgical leaders think about building the academic surgery enterprise. This discussion was inspired by a couple of recent papers in Annals of Surgery that stirred up a lot of conversation on social media which can be found below.  Host: Cody Mullens, MD MPH — general surgery resident at University of Michigan current BTK Surgery Education Fellow (@Cody_Mullens) Guest: Justin Dimick, MD MPH — Fredrick A Coller Distinguished Professor and Chair of Surgery at the University of you Michigan and Editor in Chief at Annals of Surgery (@jdimick1) Papers:  Career Trajectory After General Surgery Residency Do Academic Program Graduates Pursue Academic Surgery? https://journals.lww.com/annalsofsurgery/abstract/2025/05000/career_trajectory_after_general_surgery_residency_.10.aspx Training the Surgeon-scientist: Time (and Money) Well Spent? https://journals.lww.com/annalsofsurgery/citation/9900/training_the_surgeon_scientist__time__and_money_.1318.aspx Introducing a New Annals of Surgery Section Professional Development for the Contemporary Surgeon https://journals.lww.com/annalsofsurgery/fulltext/2025/08000/introducing_a_new_annals_of_surgery_section_.8.aspx Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listen BTK Fan Favorites:  General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-review Trauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlas Dominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkship Download our App: Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049 Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

This week we're traveling back to the 1960s with Nickel Boys! Join us as we learn about the horrific excavations of the Dozier School, the circulation of MLK speeches, Mexican-American identity in the South, and more! Sources: David Canfield Interview with RaMell Ross and Aunjanue Ellis-Taylor, Vanity Fair: https://www.vanityfair.com/hollywood/story/nickel-boys-telluride-exclusive-awards-insider?srsltid=AfmBOor0GmWj9WdElwUsFDSFjin9iJFcXiJGYeKF1ZkLFVGHvogkPHAI How Nickel Boys Was Filmed in First-Person POV: https://www.theverge.com/24318489/nickel-boys-ramell-ross-interview-first-person-cinematography Wikipedia: https://en.wikipedia.org/wiki/Nickel_Boys https://voicesofdemocracy.umd.edu/dr-martin-luther-king-jr-long-not-long-speech-text/ 1968 records, https://www.ebay.com/itm/256940070706?itmmeta=01K2N47HV7MRK73AZVCR13RX76&hash=item3bd2d25732:g:8r0AAOSwBGtoLQ7T&itmprp=enc%3AAQAKAAAA4MHg7L1Zz0LA5DYYmRTS30mP1%2Bszy%2Bf6oVsASGa76%2BT6T7uHacf7Cm%2FjdA%2ByTSvnvFH9qx4MXJebysIfG0bnMzw%2Frg1%2Fj2ZpEvbyaNVVJL8v8uA6ZDH637qT9DBURWwR5AP6X2UyjS84oaicywqrtGRJFmTDHiPdM3AOcdz6K1n9Sg9tqBwFtSjNZN087eDcc2UAPoK1nDJR1pEwKU43A5kTdTzxyUhfWrR84X1Wvn%2F5wP%2Fy%2FZvE88xfgNhiiK%2BHFWS9IiOayG2pBLCwn7ToT1GMXB8COAbYKcPx4%2B%2FF7pie%7Ctkp%3ABk9SR-SfnqSVZg,  https://www.ebay.com/itm/387262357112?itmmeta=01K2N47HV6C6JWENTA1FTVXKMD&hash=item5a2aa29e78:g:n2oAAOSwhKNmrrU-&itmprp=enc%3AAQAKAAAA4MHg7L1Zz0LA5DYYmRTS30m7rHgwCXW5OKCOZBpIuqTDUa8e4Fr6cjGgrnFXY1aiv3R98Ks0x7IkOcBlGJLQthx%2F6C9%2FiHxMFXf5Eu6o0Zyx73WrPpLQ23k2CC1sXLZLjxlzxqNofeY77UCrEUpDt07MjmRwneQ7hfCYySVT%2FHnEqbYH80QduZE01AADrpxFU19AXRUVL4OZpq7uKVG5%2F75WwJbYkvQpU04GmdY1wQgNuF3vEB7kdkDm5o4CeHpXtCZI%2FUMg1Jv1cpG6MKAoWypcYkmc9TmbkVgDdQEHvd6T%7Ctkp%3ABk9SR-KfnqSVZg Jarrod Hanson and Ruben Donato, "The Braceros: Mexican Workers in the Jim Crow South, 1949-1951," Social Education 83, no.1 (2019): 51-57.  Julie M. Weise, "Mexican Nationalisms, Southern Racisms: Mexicans and Mexican Americans in the U.S. South, 1908-1939," American Quarterly 60, no.3 (2008): 749-77.  Tyina Steptoe, ""Blaxicans" and Black Creoles," in Houston Bound: Culture and Color in a Jim Crow City (University of California Press, 2016). https://www.jstor.org/stable/10.1525/j.ctt19633hq.10   Erin Kimmerle et al, Report, Documentation of the Boot Hill Cemetery (8JA1860) at the Former Arthur G. Dozier School for Boys: Interim Report, 2012  https://digitalcommons.usf.edu/cgi/viewcontent.cgi?article=1000&context=dozier_school  Erin Kimmerle, "Forensic Anthropology in Long-Term Investigations: 100 Cold Years," Annals of Anthropological Practice 38, 1

Correva il 15° secolo a.C., per intenderci, circa 1400 anni prima del nostro Anno Zero. In un'epoca in cui i Faraoni erano considerati divinità in terra e l'Egitto era una superpotenza del mondo antico. Al comando di questo regno si trovava Thutmose III, un faraone destinato a fare la storia, tra i più ricordati. Ma una minaccia si levava all'orizzonte.La sfida arrivava da una regione a nord-est dell'impero egizio, lungo la costa del Mediterraneo, che i testi antichi chiamano Canaan. E il faraone Thutmose III decise di muovere guerra proprio lì, per cancellare l'esercito ribelle con una battaglia campale. Quella che viene definita, spesso, la prima battaglia della storia.Lorenzo Manara è scrittore di libri storici e fantasy. Acquista subito i miei romanzi!

You use ketamine. I use ketamine. We all use ketamine. But… how safe it is, really? A new study out of Toronto suggests 30% of patients who receive ketamine have adverse events, a rate higher than seen in the ED. What are we to make of this? I bring Dr Remle Crowe on to discuss…Citations:1.     Kwong JL, Verbeek PR, Leong YC, Turner L, Huiskamp M, Drennan IR, Francom S, Ropp S, Cheskes S: Paramedic use of ketamine for severe agitation and violence. Can J Emerg Med. doi: 10.1007/s43678-025-00963-w (Epub ahead of print).2.     Fernandez AR, Bourn SS, Crowe RP, Bronsky ES, Scheppke KA, Antevy P, Myers JB: Out-of-Hospital Ketamine: Indications for Use, Patient Outcomes, and Associated Mortality. Annals of Emergency Medicine. 2021;78(1):123–31.3.     Brown LH, Crowe RP, Pepe PE, Miller ML, Watanabe BL, Kordik SS, Wampler DA, Page DI, Fernandez AR, Bourn SS, et al.: Adverse events following emergent prehospital sedation of patients with behavioral emergencies: A retrospective cohort study. The Lancet Regional Health - Americas. 2022;May;9:100183.

Mast cell activation syndrome (MCAS) is a confusing and often misunderstood condition. If you've ever wondered about MCAS symptoms, serum tryptase testing, or how treatments like antihistamines, sodium cromolyn, and even omalizumab fit in, this episode is here to help. We review the findings from “Management of indolent mastocytosis and mast cell activation syndrome - A clinical yardstick,” published in June 2025 in The Annals of Allergy, Asthma & Immunology. Because the paper covers both diseases, we've split it into two parts. This episode focuses on mast cell activation syndrome (MCAS). GET THE INFOGRAPHIC - summary of this episode What we cover in our episode about mast cell activation syndrome: Yardsticks explained: Why the ACAAI uses yardsticks as practical, interim guidelines before full consensus statements are available. Classifying mast cell disorders: Primary (clonal), secondary (allergy/autoimmune), and idiopathic (MCAS). MCAS diagnosis criteria: Symptoms in 2 or more organ systems, objective evidence (serum tryptase or urinary metabolites tests), and positive response to therapy. Treatment strategies: Include trigger avoidance, H1/H2 antihistamines, leukotriene blockers, mast cell stabilizers (such as cromolyn and aspirin), off-label biologics like omalizumab, and epinephrine. Neuropsychiatric symptoms: Brain fog, anxiety, and depression are common and require multidisciplinary management. The Itch Review, hosted by Dr. Gupta, Kortney, and Dr. Blaiss, explores allergy and immunology studies, breaking down complex research in conversations accessible to clinicians, patients, and caregivers. Each episode provides key insights from journal articles and includes a one-page infographic in the show notes for easy reference. Made in partnership with The Allergy & Asthma Network. Thanks to Blueprint Medicines for sponsoring today's episode.  This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

A silent danger lurks within the descending thoracic aorta. While most Type B aortic dissections are managed medically, up to half of these patients will either require life-saving surgery or die within just five years. So how do we separate those who will quietly recover from those on the edge of catastrophe? How do we protect the spinal cord, bowel, and limbs from the devastating consequences of malperfusion? Join the University of Michigan Department of Vascular Surgery as they tackle the high-stakes decisions behind managing this unpredictable disease—where timing is critical, interventions are evolving, and lives hang in the balance. Hosted by the University of Michigan Department of Vascular Surgery: ·       Robert Beaulieu, Program Director ·       Frank Davis, Assistant Professor of Surgery ·       Luciano Delbono, PGY-5 House Officer ·       Andrew Huang, PGY-4 House Officer ·       Carolyn Judge, PGY-2 House Officer Learning Objectives: 1.         Discuss general approach to diagnosis and management of TBAD. 2.         Identifying high-risk features in uncomplicated TBAD and understanding their role in determining the need for surgical management. 3.         Review endovascular techniques for managing malperfusion of the limbs, viscera, and spinal cord and discuss associated decision making. References:  Authors/Task Force Members, Czerny, M., Grabenwöger, M., Berger, T., Aboyans, V., Della Corte, A., Chen, E. P., Desai, N. D., Dumfarth, J., Elefteriades, J. A., Etz, C. D., Kim, K. M., Kreibich, M., Lescan, M., Di Marco, L., Martens, A., Mestres, C. A., Milojevic, M., Nienaber, C. A., … Hughes, G. C. (2024). EACTS/STS Guidelines for Diagnosing and Treating Acute and Chronic Syndromes of the Aortic Organ. The Annals of Thoracic Surgery, 118(1), 5–115. https://doi.org/10.1016/j.athoracsur.2024.01.021 de Kort, J. F., Hasami, N. A., Been, M., Grassi, V., Lomazzi, C., Heijmen, R. H., Hazenberg, C. E. V. B., van Herwaarden, J. A., & Trimarchi, S. (2025). Trends and Updates in the Management and Outcomes of Acute Uncomplicated Type B Aortic Dissection. Annals of Vascular Surgery, S0890-5096(25)00004-4. https://doi.org/10.1016/j.avsg.2024.12.060 Eidt, J. F., & Vasquez, J. (2023). Changing Management of Type B Aortic Dissections. Methodist DeBakey Cardiovascular Journal, 19(2), 59–69. https://doi.org/10.14797/mdcvj.1171 Lombardi, J. V., Hughes, G. C., Appoo, J. J., Bavaria, J. E., Beck, A. W., Cambria, R. P., Charlton-Ouw, K., Eslami, M. H., Kim, K. M., Leshnower, B. G., Maldonado, T., Reece, T. B., & Wang, G. J. (2020). Society for Vascular Surgery (SVS) and Society of Thoracic Surgeons (STS) reporting standards for type B aortic dissections. Journal of Vascular Surgery, 71(3), 723–747. https://doi.org/10.1016/j.jvs.2019.11.013 MacGillivray, T. E., Gleason, T. G., Patel, H. J., Aldea, G. S., Bavaria, J. E., Beaver, T. M., Chen, E. P., Czerny, M., Estrera, A. L., Firestone, S., Fischbein, M. P., Hughes, G. C., Hui, D. S., Kissoon, K., Lawton, J. S., Pacini, D., Reece, T. B., Roselli, E. E., & Stulak, J. (2022). The Society of Thoracic Surgeons/American Association for Thoracic Surgery Clinical Practice Guidelines on the Management of Type B Aortic Dissection. The Annals of Thoracic Surgery, 113(4), 1073–1092. https://doi.org/10.1016/j.athoracsur.2021.11.002 Papatheodorou, N., Tsilimparis, N., Peterss, S., Khangholi, D., Konstantinou, N., Pichlmaier, M., & Stana, J. (2025). Pre-Emptive Endovascular Repair for Uncomplicated Type B Dissection—Is This an Option? Annals of Vascular Surgery, S0890-5096(25)00007-X. https://doi.org/10.1016/j.avsg.2025.01.003 Trimarchi, S., Gleason, T. G., Brinster, D. R., Bismuth, J., Bossone, E., Sundt, T. M., Montgomery, D. G., Pai, C.-W., Bissacco, D., de Beaufort, H. W. L., Bavaria, J. E., Mussa, F., Bekeredjian, R., Schermerhorn, M., Pacini, D., Myrmel, T., Ouzounian, M., Korach, A., Chen, E. P., … Patel, H. J. (2023). Editor's Choice - Trends in Management and Outcomes of Type B Aortic Dissection: A Report From the International Registry of Aortic Dissection. European Journal of Vascular and Endovascular Surgery: The Official Journal of the European Society for Vascular Surgery, 66(6), 775–782. https://doi.org/10.1016/j.ejvs.2023.05.015 Writing Committee Members, Isselbacher, E. M., Preventza, O., Hamilton Black Iii, J., Augoustides, J. G., Beck, A. W., Bolen, M. A., Braverman, A. C., Bray, B. E., Brown-Zimmerman, M. M., Chen, E. P., Collins, T. J., DeAnda, A., Fanola, C. L., Girardi, L. N., Hicks, C. W., Hui, D. S., Jones, W. S., Kalahasti, V., … Woo, Y. J. (2022). 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Journal of the American College of Cardiology, 80(24), e223–e393. https://doi.org/10.1016/j.jacc.2022.08.004 Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://app.behindtheknife.org/listen

What does “great” Medical Affairs look like in 2025? We talk evidence, access, patient voice, and how to work with Commercial without crossing the promotional line. Abdul Hameed Al-Khateeb, Country Medical Director, shares practical lessons on measurement, real-world evidence, and where AI actually helps.Email to your listSubject line options (pick one):Inside Medical Affairs: From Evidence to AccessThe Missing Link Between Science and PatientsWhat Great Medical Affairs Looks Like (and How to Measure It)

Why do so many women struggle with stress-related health issues without ever speaking up? In this episode, Dr. Brendan McCarthy continues his series on self-silencing in women—a powerful yet often overlooked cultural and psychological pattern. Dr. McCarthy breaks down: What “self-silencing” really means and how it shows up in everyday life The four categories of self-silencing How chronic stress and emotional suppression affect hormones, fertility, and cardiovascular health Why women face higher risks of heart disease when these patterns go unaddressed What men can do to better support their partners during PMS, perimenopause, and menopause   This conversation is about more than symptoms—it's about validation, advocacy, and the urgent need to recognize how cultural conditioning impacts women's health.   Citations: Jack, D. C., & Dill, D. (1992). The Silencing the Self Scale: Schemas of intimacy associated with depression in women. Psychology of Women Quarterly, 16(1), 97–106.       •     Jack, D. C. (1999). Silencing the self: Inner dialogues and outer realities. Harvard University Press.       •     Jack, D. C. (2011). Reflections on the silencing the self scale and its origins. Psychology of Women Quarterly, 35(3), 523–529.       •     Jakubowski, K. P., Barinas-Mitchell, E., et al. (2022). The cardiovascular cost of silence: Self-silencing and carotid atherosclerosis. Annals of Behavioral Medicine, 56(3), 282–293.       •     Ussher, J. M. (2004). Premenstrual syndrome and self-policing. Social Theory & Health, 2(1), 56–77.       •     Ussher, J. M. (2013). Diagnosing difficult women. Feminism & Psychology, 23(1), 63–77.       •     Beauboeuf-Lafontant, T. (2008). Listening past the lies. Qualitative Sociology, 31(2), 105–124.       •     Rozanski, A. (2014). Behavioral cardiology. Circulation, 129(25), 2509–2516. 1.    Jack & Dill (1992) – Developed Silencing the Self Scale. Linked to depression and poor health outcomes.       2.    Framingham Offspring Study (Jack, 2011) – Women with high self-silencing had ↑ heart disease and premature death.       3.    Jakubowski et al. (2022, Annals of Behavioral Medicine) – Self-silencing predicted ↑ carotid atherosclerosis in midlife women.       4.    Beauboeuf-Lafontant (2008, Qualitative Sociology) – Black women's depression tied to silencing under cultural expectations of strength.       5.    Ussher (2004, 2013, 2023) – Purity/self-policing associated with self-blame and somatic illness pathways.       6.    Rasmussen (2014) – Self-silencing linked to anger suppression, leading to somatic symptoms.       7.    Peterson (2015) – Shame and silence in purity narratives obstruct preventive health care.       8.    CRP & Stress Studies – High CRP consistently linked to psychosocial stress (Rozanski, 2014, Circulation).   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.  

We've covered pre-oxygenation strategies and intubation alot on this podcast, mayber more than anyting else. We covered the definition of FPS in E74, the DEVICE trial on DL vs VL in E75, and the PREOXI trial of NIV vs Mask Pre-oxygenation in E86. Now we have another Preoxygenation paper, this one that reports no difference between preoxygenation with BVM and face mask. WTAF? Better listen, because it turns out words matter, definitions are... definitional, and we absolutely MUST read more than just the abstract.  Citations:1.     Gottlieb M, Alexander R, Love AK: Comparison of Preoxygenation Strategies for Intubation of Critically Ill Patients. Annals of Emergency Medicine. doi: 10.1016/j.annemergmed.2025.06.621 (Epub ahead of print).2.     Chou CD, Palakshappa JA, Haynie H, Garcia K, Long D, Gibbs KW, White HD, Ghamande S, Dagan A, Stempek S, et al.: Association of Two Preoxygenation Approaches With Hypoxemia During Tracheal Intubation: A Secondary Analysis. Annals of Emergency Medicine. doi: 10.1016/j.annemergmed.2025.06.003 (Epub ahead of print).3.     Pitre T, Liu W, Zeraatkar D, Casey JD, Dionne JC, Gibbs KW, Ginde AA, Needham-Nethercott N, Rice TW, Semler MW, et al.: Preoxygenation strategies for intubation of patients who are critically ill: a systematic review and network meta-analysis of randomised trials. The Lancet Respiratory Medicine. 2025;July;13(7):585–96.4.     Gibbs KW, Semler MW, Driver BE, Seitz KP, Stempek SB, Taylor C, Resnick-Ault D, White HD, Gandotra S, Doerschug KC, et al.: Noninvasive Ventilation for Preoxygenation during Emergency Intubation. N Engl J Med. doi: 10.1056/NEJMoa2313680 (Epub ahead of print).5.     Prekker ME, Driver BE, Trent SA, Resnick-Ault D, Seitz KP, Russell DW, Gaillard JP, Latimer AJ, Ghamande SA, Gibbs KW, et al.: Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults. N Engl J Med. 2023;June 16;389(5):418–29.6.     Trent SA, Kaji AH, Carlson JN, McCormick T, Haukoos JS, Brown CA, National EARI: Video Laryngoscopy is Associated With First-Pass Success in Emergency Department Intubations for Trauma Patients: A Propensity Score Matched Analysis of the National Emergency Airway Registry. Ann Emerg Med. doi: 10.1016/j.annemergmed.2021.07.115 (Epub ahead of print).

If you read the Annals of Tigernach, you will find that Máel Brigte mac Mothlachán killed Rogallach mac Uatach, King of Connacht, in battle, because the Uí Briúin tribe had been encroaching on the territory of the Corco Cullu, and so it was one of those normal murders. However, if you read the renowned and beloved Geoffrey Keating, you will discover that no, Rogallach, riding his white horse, was killed by servants, after a dispute about who had actually killed a deer, but before that Rogallach had been living a version of Oedipus, sleeping with his daughter, who had been, as an infant sent out to die, but a huntsman saved her, and then later her dad met her and incestuous relations followed. We do talk about Connacht, and Rogallach, and Máel Brigte mac Mothlachán, but really what Anne is concerned about is the inability of some historians to tell the difference between history and storytelling, and Michelle, bless her heart, is driven to sputtering outrage by the inability of some scholars to tell you where they found the stuff, history or story, either one.

Qianlong's empire shines as a beacon of both martial might and cultural splendor, yet its mirrored glory hides truths too fragile for celestial ambitions. Time Period Covered: ~1770-1799CE Major Historical Figures: Qing Empire: The Qianlong Emperor (Aisin-Gioro Hongli) [r. 1735–1796, d. 1799] Grand Councillor Heshen [1750-1799] Great Britain: Lord George Macartney (1737-1806) Major Sources Cited: Bland, J.O.P. and Lord Edmund Backhouse. Annals and Memoirs of the Court at Peking. Fairbank, John King, and Denis Twitchett, eds. The Cambridge History of China, Volume 9, Part 1: The Ch'ing Empire to 1800. Perdue, Peter. China Marches West: The Qing Conquest of Central Eurasia. Woodside, Alexander. The Qing in the Age of Confucian Empire. Yuan, Wei. Shengwu ji (Sacred Military Achievements). Learn more about your ad choices. Visit megaphone.fm/adchoices

US Health Secretary RFK Jr's call to retract a study on childhood vaccines is resisted by the journal. Also antibiotics get designed by AI, and a new way for stars to die. A study focussing on Danish childhood vaccination data has attracted the US Secretary for Health's anger, as RFK jr calls for the journal in which it was published, the Annals of Internal Medicine, to retract it. The Editor, Christine Laine, talk to Science in Action about the strengths and challenges of observational studies. The cuts to prestigious US federal science funded research continue, as last week it was announced that $500 million funding for future mRNA vaccines would be withdrawn. Barney Graham, one of the pioneers in the field and prominent during the Covid vaccines, argues that the research will still happen, though maybe not in the US, as mRNA has become a fundamental area of global research. Meanwhile, strides are being made in the field of synthetic biology as Jim Collins and colleagues at MIT and Harvard have used AI to design potentially viable antibiotics for two important drug-resistant superbugs. Previously, AI has been used to comb through libraries of known antibiotics. This study has gone a step further, and used generative AI to design new ones, that can then be synthesised using real chemicals. Though a long way from being prescribable drugs, the team think this could herald a new golden age of antibiotic development – something which has been lacking in recent decades. Finally, it seems astronomers may have discovered a new way for a star to die, sort of. Supernova 2023zkd was seen to explode back in 2023, found by a team looking for odd events. It didn't seem quite like normal supernovae, in that it took a bit longer to die down. Then the team looked back, and noticed that it had also been getting slowly brighter for almost a year. At 730 million light years away, in a galaxy far, far away, it also seemed to have been stripped of all its hydrogen and even stranger yet, appeared to have exploded twice. As Ashley Villar of the Harvard Smithsonian Center for Astrophysics explains, the almost unique observation fits with a model of the huge star getting closer to a black hole, the gravity of which may have disrupted the star enough to cause it to explode. Presenter: Roland Pease Producer: Ella Hubber with Alex Mansfield Production Coordinator: Jana Bennett-Holesworth (Image: Child getting a vaccine. Credit: Luis Alvarez via Getty Images)

Vinay Prasad is back at the FDA as chief of the FDA's Center for Biologics Evaluation and Research. Prasad's return—which hit the news wires Saturday morning—came just 10 days after his unexpected exit on July 29, following blowback over the saga involving Sarepta Therapeutics' Duchenne muscular dystrophy gene therapy Elevidys, and a campaign by conversative personalities to oust the outspoken physician.Elsewhere in the government, Gray Delany, former head of HHS' and President Donald Trump's Make America Healthy Again agenda, has been fired—days after Health and Human Services Secretary Robert F. Kennedy Jr. axed 22 mRNA vaccine contracts under the Biomedical Advanced Research and Development Authority. Delany's ouster came after he allegedly butted heads with other agency officials over how announcements were made, according to reporting from Endpoints News. The mRNA contract cuts, meanwhile, have sparked criticism from the scientific community and concern that the growing anti-mRNA sentiment could also have a negative effect on research for cancer therapeutics.In somewhat related news, the Annals of Internal Medicine is refusing to retract a large-scale study it ran in July that pointed to the lack of an association between childhood aluminum exposure through vaccination and chronic conditions, despite Kennedy's criticism. In an op-ed published earlier this month, the Health Secretary took issue with the study's design.In obesity news, biopharma darling Eli Lilly suffered a rare chink in its normally impenetrable GLP-1 armor. The first Phase III trial for oral weight loss therapy orforglipron read out last week, and the results were underwhelming, at least to Wall Street. Truist Securities wrote that the data support approval but “leaves room for competition.” This is good news for a whole host of companies, including Roche, Viking, Terns and Rhythm Pharmaceuticals, who all have weight loss pills at various stages of development.And in gene therapy, the hits just keep coming. The FDA has limited the use of bluebird bio's gene therapy Skysona to patients with cerebral adrenoleukodystrophy for whom no other therapies or stem cell donors are available, due to a heightened risk of blood cancers. This follows safety issues in gene therapy trials experienced by Allogene, and, of course, Sarepta Therapeutics. This week in ClinicaSpace, Dan Samorodnitsky explored the future of AAV technology. And in BioPharm Executive, Annalee Armstrong sat down with Chris Anzalone, CEO of Arrowhead Pharmaceuticals—Sarepta's key strategic partner—to learn how his company has been weathering the storm.

In the July issue of the Annals of Emergency Medicine podcast, Ryan and Rory discuss treatments for agitated delirium in children, albumin for septic shock, and much more.

On this episode, the podcast crew discusses the recent introduction of video laryngoscopy with recording capability at MCHD. What device did you use? How did you train? What lessons have you learned? All these and more will be addressed and answered. REFERENCES: 1. Zhao, Y., Zang, B., & Wang, Q. (2024). The Effectiveness of Bougie Use on First-Attempt Success in Tracheal Intubations. Annals of emergency medicine, 84(3), 331–332. 2. Weingart, S. D., Barnicle, R. N., Janke, A., Bhagwan, S. D., Tanzi, M., McKenna, P. J., Bracey, A., & Resuscitationists Research Group (2023). A taxonomy of key performance errors for emergency intubation. The American journal of emergency medicine, 73, 137–144.

Die Themen in den Wissensnachrichten +++ Forschende aus Kanada beobachten höheres Psychose-Risiko beim Kiffen +++ Thüringer Forschende beanspruchen ältesten Bratwurst-Stand für Erfurt +++ Wenn KI-Antworten zu Salz zur Vergiftung führen +++**********Weiterführende Quellen zu dieser Folge:Cannabis and psychosis. Canadian Medical Association Journal, 11.08.2025Geschichte der Bratwurst. Zeitleiste vom Deutschen Bratwurstmuseum im Mühlhausen/ThüringenA Case of Bromism Influenced by Use of Artificial Intelligence. Annuals of Internal Medicine: Clinical Cases, 05.08.2025Contribution of lake littoral zones to the continental carbon budget. Nature Geoscience, 04.08.2025Global recruitment patterns and placebo responses in clinical trials of rheumatoid arthritis. Annals of the Rheumatic Diseases, 01.08.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Listener feedback on SURPASS CVOT, AF ablation and the limits of meta-analyses, a Watchman alert from FDA, and oral anticoagulation choices in elderly patients are discussed by John Mandola, MD, in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I SURPASS CVOT This Week in Cardiology Podcast, August 1 https://www.medscape.com/viewarticle/1002781 Mounjaro Appears More Heart Protective Than Trulicity in Trial Of Eli Lilly Diabetes Drugs https://www.medscape.com/s/viewarticle/mounjaro-proves-more-heart-protective-than-trulicity-trial-2025a1000kct II Catheter and Surgical AF ablation Catheter and Surgical Ablation for AF: Meta-Analysis https://www.acpjournals.org/doi/10.7326/ANNALS-25-00253 III Watchman Air Embolism Alerts Looming Pay Cut to LAAO Triggers Objection From Card Groups https://www.medscape.com/viewarticle/looming-pay-cut-laao-triggers-objection-card-groups-2025a1000l0j FDA Alert https://www.fda.gov/medical-devices/medical-device-recalls/early-alert-watchman-access-system-issue-boston-scientific IV Switching Oral Anticoagulants in Frail Older Adults Patients FRAIL AF Trial https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.066485 COMBINE AF Substudy https://doi.org/10.1016/j.jacc.2025.05.060 The Most Important Study From ESC: FRAIL-AF https://www.medscape.com/viewarticle/996063 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

Yalnızlık dost mu düşman mı arkadaşlar biri artık şunu açıklasın! Ben şahsen bizzat kendim yalnızım biliyorsunuz ve inanır mısınız bundan da mutluyum. Her ne kadar bazıları yalnızlığı bir sorun, yalnız insanları "bozuk" olarak görseler de bence öyle değil. Peki yalnızlık ne zaman sorun? Yalnızlığın ne kadarı sorun? Sınırı nerden çekicez? Hepsini araştırdım sizin için; yalnızlık dost mu düşman mı BEN bu bölümde açıklıyorum! Kaynakça: 1-Cacioppo, J. T., & Cacioppo, S. (2018). The growing problem of loneliness. The Lancet, 391(10119), 426. https://doi.org/10.1016/S0140-6736(18)30142-9 2-Hawkley, L. C., & Cacioppo, J. T. (2010). Loneliness matters: A theoretical and empirical review of consequences and mechanisms. Annals of Behavioral Medicine, 40(2), 218–227. https://doi.org/10.1007/s12160-010-9210-8 3-Lieberman, M. D., & Eisenberger, N. I. (2009). Pains and pleasures of social life. Science, 323(5916), 890–891. https://doi.org/10.1126/science.1170008 4-Nowland, R., Necka, E. A., & Cacioppo, J. T. (2018). Loneliness and social internet use: Pathways to reconnection in a digital world? Perspectives on Psychological Science, 13(1), 70–87. https://doi.org/10.1177/1745691617713052 5-Nguyen, T. V., Weinstein, N., & Ryan, R. M. (2022). The bright side of solitude: The role of autonomy in positive solitary experiences. Personality and Social Psychology Bulletin, 48(2), 279–293. https://doi.org/10.1177/01461672211014200 6-Shiovitz-Ezra, S., & Ayalon, L. (2012). Situational versus chronic loneliness as risk factors for all-cause mortality. International Psychogeriatrics, 24(3), 440–447. https://doi.org/10.1017/S1041610211001957 7-Rokach, A. (2015). The psychology of solitude: Meaning and experience. Journal of Psychology & Psychotherapy, 5(6). https://doi.org/10.4172/2161-0487.1000203 8-Holt-Lunstad, J., Smith, T. B., Baker, M., Harris, T., & Stephenson, D. (2015). Loneliness and social isolation as risk factors for mortality: A meta-analytic review. Perspectives on Psychological Science, 10(2), 227–237. https://doi.org/10.1177/1745691614568352 9-Layous, K., Nelson, S. K., & Lyubomirsky, S. (2013). What triggers prosocial effort? A test of the empathy–altruism hypothesis. Motivation and Emotion, 37(3), 447–457. https://doi.org/10.1007/s11031-012-9331-7 10-Reading University. (2023). How solitude boosts wellbeing. University of Reading News. Retrieved from https://www.reading.ac.uk/news/2023/Research-News/How-solitude-boosts-wellbeing 11-New York Post. (2025). 3 major benefits of being alone, according to a psychologist. Retrieved from https://nypost.com/2025/04/13/health/3-major-benefits-of-being-alone-according-to-a-psychologist ------- Podbee Sunar ------- Bu podcast, Garanti BBVA reklamı içermektedir. Bonus Platinum'un avantajlarını keşfet!

Welcome to the first episode in a five-part series on self-silencing and its profound effect on women's health. I'm Dr. Brendan McCarthy, Chief Medical Officer at Protea Medical Center, and in this episode, I break down how self-silencing — the learned suppression of one's needs, emotions, and voice — directly influences weight gain, hormone disruption, autoimmunity, cardiovascular risk, and more. This is a deeply personal and evidence-backed conversation rooted in decades of clinical experience and medical research. I discuss real patient patterns, the emotional layers behind common health complaints, and why this silent epidemic deserves more space in medicine. If you or someone you love has ever struggled with feeling unheard, unseen, or overwhelmed by caretaking roles, this is for you.   Citations: 13] Jakubowski, K. P., Barinas-Mitchell, E., Chang, Y.-F., Maki, P. M., Matthews, K. A., & Thurston, R. C. (2021). The Cardiovascular Cost of Silence: Relationships Between Self-silencing and Carotid Atherosclerosis in Midlife Women. *Annals of Behavioral Medicine, 56*(3), 282–290. DOI: 10.1093/abm/kaab046 [27] Eyal, M. (2023, October 3). Self-Silencing Is Making Women Sick. *TIME*. [5] Jack, D. C. (2010, March 29). Silencing the Self Theory. *OUPblog*.   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.  

16th-century Swiss physician Paracelsus was frustrated with established medical practice and academia and he was sometimes on the lam because of his beliefs. He wrote at length about the idea that items in the natural world carried “signatures” in their appearance that could tell you visually how they could be used medicinally. Research: Bennett, B.C. Doctrine of Signatures: An explanation of medicinal plant discovery or Dissemination of knowledge?. Econ Bot 61, 246–255 (2007). https://doi.org/10.1663/0013-0001(2007)61[246:DOSAEO]2.0.CO;2 Dafni, Amots, and E. Lev. “The Doctrine of Signatures in Present-Day Israel.” Economic Botany, vol. 56, no. 4, 2002, pp. 328–34. JSTOR, http://www.jstor.org/stable/4256605 “The Doctrine Of Signatures.” The British Medical Journal, vol. 1, no. 627, 1873, pp. 19–19. JSTOR, http://www.jstor.org/stable/25233757 “The Doctrine of Signatures.” John Moore Museum. May 11, 2021. https://www.johnmooremuseum.org/the-doctrine-of-signatures/ The Editors of Encyclopaedia Britannica. "laudanum". Encyclopedia Britannica, 19 Jul. 2025, https://www.britannica.com/science/laudanum The Editors of Encyclopaedia Britannica. "Peasants’ War". Encyclopedia Britannica, 20 Aug. 2020, https://www.britannica.com/event/Peasants-War Grzybowski, Andrzej and Katarzyna Pawlikowska-Łagód. “Some lesser-known facts on the early history of syphilis in Europe.” Clinics in Dermatology. Volume 42, Issue 2. 2024. Pages 128-133. https://doi.org/10.1016/j.clindermatol.2023.12.003. Hargrave, John G. "Paracelsus". Encyclopedia Britannica, 3 Jul. 2025, https://www.britannica.com/biography/Paracelsus “The history of syphilis part two: Treatments, cures and legislation.” Science Museum UK. Nov. 8, 2023. https://www.sciencemuseum.org.uk/objects-and-stories/history-syphilis-part-two-treatments-cures-and-legislation Kikuchihara, Y., Hirai, H. (2015). Signatura Rerum Theory. In: Sgarbi, M. (eds) Encyclopedia of Renaissance Philosophy. Springer, Cham. https://doi.org/10.1007/978-3-319-02848-4_405-1 Lund, F B. “PARACELSUS.” Annals of surgery vol. 94,4 (1931): 548-61. doi:10.1097/00000658-193110000-00009 Michaleas, Spyros N et al. “Theophrastus Bombastus Von Hohenheim (Paracelsus) (1493-1541): The eminent physician and pioneer of toxicology.” Toxicology reports vol. 8 411-414. 23 Feb. 2021, doi:10.1016/j.toxrep.2021.02.012 Paracelsus. “Of the supreme mysteries of nature. : Of the spirits of the planets. of occult philosophy. The magical, sympathetical, and antipathetical cure of wounds and diseases. The mysteries of the twelve signs of the zodiack.” London. 1656. Accessed online: https://archive.org/details/paracelsvsofsupr00para/page/n9/mode/2up Simon, Matt. “Fantastically Wrong: The Strange History of Using Organ-Shaped Plants to Treat Disease.” Wired. July 16, 2014. https://www.wired.com/2014/07/fantastically-wrong-doctrine-of-signatures/ Tampa, M. et al. “Brief history of syphilis.” Journal of medicine and life vol. 7,1 (2014): 4-10.https://pmc.ncbi.nlm.nih.gov/articles/PMC3956094/#R6 Waite, Arthur Edward. “Lives of alchemystical philosophers based on materials collected in 1815 : and supplemented by recent researches with a philosophical demonstration of the true principles of the magnum opus, or great work of alchemical re-construction, and some account of the spiritual chemistry.” London. G. Redway. 1888. Accessed online: https://archive.org/details/livesofalchemyst1888wait See omnystudio.com/listener for privacy information.

Most Americans hardly knew about autism in the 1980s and '90s. Then, as if suddenly, autism became big news in the 2000s. And the rate of autism has increased since, including diagnosis among adults. But how did this happen?

Hosts Pastor Robert Baltodano and Pastor Lloyd Pulley Question Timestamps: Load Hauler, YouTube (3:26) - What happened to the Book of the Annals? Have they been recovered? Denise, Facebook (4:29) - Can you clarify the angel telling Mary to name the baby "Immanuel," and then they named him "Jesus?" Carlos, NJ (6:43) - Can you clarify 1 Thessalonians 4:13-18 versus Luke 16? Maritza, email (11:12) - What will we be judged for, or have to give an account for, if all our sins are forgiven? Jaysha, NJ (14:24) - Is it true that Satan was once an angel, and is now a fallen angel? Is that why we all fall short and Jesus had to die on the cross? Joyce, email (16:41) - What are your thoughts on the Geneva Bible? Did King James change the Bible? Cleveland, VA (20:36) - What was the shedding of blood given for the remission of Adam's sin? Wendy, NJ (22:01) - When does the story of the sheep and the goats in Matthew 25 take place, before or after the Millennial Kingdom? Who is it about? Levi, NY (26:10, continued after break at 33:33) - Didn't Eve sin first? Lena, NY (37:18) - Can God destroy? Does He destroy completely? Calvary Young Adults Q&A (46:19) - How should I be preparing to be a faithful and submissive wife? George, TX (50:29) - How do I revitalize my wife's faith? Ask Your Question: 888-712-7434 Answers@bbtlive.org

Reference: Bourke EM, et al. PEAChY-O: Pharmacological Emergency Management of Agitation in Children and Young People: A Randomized Controlled Trial of Oral Medication. Annals of Emergency Medicine. Feb 2025 Date: April 29, 2025 Guest Skeptic: Dr. Brad Sobolewski, is a pediatric emergency medicine physician at Cincinnati Children's Hospital and Professor of Pediatrics at the University […] The post SGEM#480: In the End It Doesn't Even Matter: Oral Olanzapine or Diazepam for Pediatric Agitation first appeared on The Skeptics Guide to Emergency Medicine.

Por Yaiza Santos Le llevó un buen rato analizar el sintagma «memoria democrática» para comentar lo que el Gobierno ha ordenado hacer con la jefatura de Policía de Vía Layetana. Bien sabe él que no son más que las migajas a las que está obligado Sánchez para alimentar a los nacionalistas si quiere permanecer en el poder los años que le quedan, pero no quiso dejar de proponer una resignificación –como dicen– de la resignificación. Nadie niega que en ese edificio se cometieran actos indignos contra la humanidad, y que desde allí se trazaran estrategias para que la libertad y la dignidad florecieran en nuestro país. Pero eso no fue lo único que ocurrió en él. Desde allí, también, honrados empleados del Estado trabajaron en la defensa de la democracia en España, por ejemplo contra el terrorismo. Y no digamos el papel que tuvieron en el infausto 1 de octubre, cuando fueron los únicos funcionarios que cumplieron con su obligación. ¡Democrática! Así pues, propone que al lado de la plaquita que coloquen sobre las torturas del franquismo, que pongan una también recordando a los héroes de la Vía Layetana. Qué cansado está del horóscopo de la Aemet, que tiene en alerta roja a Barcelona por una tormenta de verano. Lo tiene dicho: no puede ser ese rojo el mismo que el de la trágica dana, porque entonces se estará atentando contra la seguridad. Sigue con mucha atención las crónicas del valet de chambre Cué y ciertamente se alegra de que el presidente esté fuerte y esté bien. ¡Al menos hasta el próximo informe de la UCO! La degradación a la que los políticos someten la esfera pública no debe confundirnos, advirtió a Santos: bien está que el jefe del Ejecutivo y su mujer viajen en Falcon adonde necesiten. Expresó su interés por el caso Epstein y el papel de Trump y, como de costumbre, apostilló un nuevo paper candente: cuando un hallazgo científico nos parece moralmente ofensivo... lo atacamos como si fuera una amenaza personal. ¡Humano, muy humano! Y fue así que Espada yiró.Bibliografía Cory Clark et al., «Los hallazgos científicos moralmente ofensivos activan la charlatanería cognitiva», Annals of the New York Academy of Sciences, 8 de junio de 2025See omnystudio.com/listener for privacy information.

Send us a textRiley's doctor recommended bariatric surgery as the solution to their health concerns, but when Riley came to me for advice, I realized they hadn't been told about the real risks. From anastomosis leaks with 15% mortality rates to spontaneous bowel perforations years later, the complications of weight loss surgery extend far beyond what most patients are counseled about. In this episode, I walk through the evidence-based risks that every patient deserves to know before making this life-altering decision, because informed consent requires the whole truth. If you or someone you know is considering weight loss surgery, then be sure to send them a link to this episode!References:Lim, Robert et al. “Early and late complications of bariatric operation.” Trauma surgery & acute care open vol. 3,1 e000219. 9 Oct. 2018Silva, Ana Flávia da et al. “Risk factors for the development of surgical site infection in bariatric surgery: an integrative review of literature.” Revista latino-americana de enfermagem vol. 31 (2023)Complications of bariatric surgery: presentation and emergency management--a review.” Annals of the Royal College of Surgeons of England vol. 91,4 (2009): 280-6.Benotti, Peter et al. “Risk factors associated with mortality after Roux-en-Y gastric bypass surgery.” Annals of surgery vol. 259,1 (2014): 123-30. Coupaye, Muriel et al. “Evaluation of incidence of cholelithiasis after bariatric surgery in subjects treated or not treated with ursodeoxycholic acid.” Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery vol. 13,4 (2017): 681-685 Husain, Syed et al. “Small-bowel obstruction after laparoscopic Roux-en-Y gastric bypass: etiology, diagnosis, and management.” Archives of surgery (Chicago, Ill. : 1960) vol. 142,10 (2007): 988-93 Seeras K, Acho RJ, Lopez PP. Roux-en-Y Gastric Bypass Chronic Complications. [Updated 2023 Jun 5]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK519489/Got a question for the next podcast? Let me know! Connect With Me FREE GUIDES: evidence-based, not diet nonsense NEWSLETTER: Life-changing insights straight to your inbox UNSHRINKABLE: Find out why your body is not designed to shrink MASTERCLASSES: All the evidence doctors should give you NO WEIGH PROGRAM: Join the revolution against weight-loss lies THE WEIGHTING ROOM: A community where authenticity thrives and every voice matters CONSULTATION: For the ultimate transformation in your healthcare journe Find me on Instagram, YouTube, and LinkedIn.

For decades, Alejandro Portes (CASBS fellow 1980-81) has been among our most distinguished scholars elucidating the causes and consequences of immigration and assimilation. René D. Flores (CASBS fellow 2023-24) engages Portes in a conversation spanning large swaths of Portes's formidable intellectual biography, including his personal journey from Cuba and its influence on his academic trajectory, as well as his approach to social science inquiry and its delivery of insights leading to some of his most celebrated and consequential works.ALEJANDRO PORTES: Princeton faculty page | CV | Univ. of Miami faculty page | Wikipedia page | on Google Scholar | Biographical sketches of Portes: American Sociological Association | National Academy of Education | Princeton | National Institutes of Health | Proceedings of the National Academy of Sciences | Robert K. Merton's full quote about Alejandro Portes is contained in the September/October 1998 issue of Footnotes, a publication of the American Sociological Association. Access the full text.  Works referenced in this episodeAlejandro Portes, "Rationality in the Slum: An Essay on Interpretive Sociology," Comparative Studies in Society and History, v13 n3, June 1972.Alejandro Portes, "Dilemmas of a Golden Exile: Integration of Cuban Refugee Families in Milwaukee," American Sociological Review, v34 n4, August 1969.Alejandro Portes and Robert Bach, Latin Journey: Cuban and Mexican Immigrants in the United States. Univ. of California Press, 1985.Alejandro Portes and Min Zhou, "The New Second Generation: Segmented Assimilation and its Variants," Annals of the American Academy of Political and Social Science, November 1993.Alejandro Portes and Ruben Rumbaut, Immigrant America: A Portrait, Univ. of California Press, 2024 (fifth ed.)Alejandro Portes and Ruben Rumbaut, Legacies: The Story of the Immigrant Second Generation, Univ. of California Press, 2001.Jennifer Lee and Min Zhou, The Asian American Achievement Paradox, Russell Sage Foundation, 2015. (Notably, Jennifer Lee was a CASBS fellow in 2002-03; Min Zhou was a CASBS fellow in 2006-06.)Bonus: 2019-20 CASBS fellow Catherine Ramírez discusses the influence of Alejandro Portes in "What Does Assimilation Mean?" Public Books, Feb. 27, 2020. The essay was written as part of CASBS's partnership with Public Books. Ramírez writes, "By showing that there are many strata in society into which people assimilate, and many outcomes of assimilation, Portes and his coauthors have enriched our understanding of the processes by which people become American, however precarious that status may be.” René D. Flores: Univ. of Chicago faculty page | CASBS page | on Google Scholar | Personal website |    Center for Advanced Study in the Behavioral Sciences (CASBS) at Stanford UniversityExplore CASBS: website|Bluesky|X|YouTube|LinkedIn|podcast|latest newsletter|signup|outreach​Human CenteredProducer: Mike Gaetani | Audio engineer & co-producer: Joe Monzel |

Edwin Howard Armstrong isn’t exactly a well-known inventor, but his work in radio literally changed communications around the globe. But his most famous invention – FM radio – became a source of constant frustration after he developed it. Research: Armstrong, Edwin H. “Frequency Modulation and Its Future Uses.” The Annals of the American Academy of Political and Social Science, vol. 213, 1941, pp. 153–61. JSTOR, http://www.jstor.org/stable/1024069 Armstrong, Edwin H. “Personalities in Science.” Scientific American, vol. 154, no. 1, 1936, pp. 3–3. JSTOR, http://www.jstor.org/stable/26144367 “First public radio broadcast.” Guinness World Records. https://www.guinnessworldrecords.com/world-records/381969-first-public-radio-broadcast “FM Inventor Dies in Fall.” The Patriot News. Feb. 2, 1954. https://www.newspapers.com/image/1094174282/?match=1&terms=%22Edwin%20Howard%20Armstrong%22 Lessing, Lawrence P.. "Edwin H. Armstrong". Encyclopedia Britannica, 14 Dec. 2024, https://www.britannica.com/biography/Edwin-H-Armstrong Lessing, Lawrence P. “Man of High Fidelity: Edwin Howard Armstrong.” Bantam. 1969. Lessing, Lawrence P. “The Late Edwin H. Armstrong.” Scientific American, vol. 190, no. 4, 1954, pp. 64–69. JSTOR, http://www.jstor.org/stable/24944524 “Proceedings of the Institute of Radio Engineers, Volume 5.” Institute of Radio Engineers. 1917. Accessed online: https://books.google.com/books?id=YEASAAAAIAAJ&source=gbs_navlinks_s “Radio Broadcast.” Garden City, N.Y.: Doubleday, Page & Co., 1922-1930. https://babel.hathitrust.org/cgi/pt?id=iau.31858044013914&view=1up&seq=277 “Telephoning Without Wires.” The Fort Wayne Journal Gazette. Oct. 20, 1907. https://www.newspapers.com/image/29125618/?match=1&terms=audion%20%22de%20Forest%22 Tsividis, Yannis. “Edwin Armstrong: Pioneer of the Airwaves.” Columbia Magazine. April 1, 2002. https://magazine.columbia.edu/article/edwin-armstrong-pioneer-airwaves Turner, H. M. “Dr. Edwin H. Armstrong, Edison Medalist.” The Scientific Monthly, vol. 56, no. 2, 1943, pp. 185–87. JSTOR, http://www.jstor.org/stable/17796 “What’s the Difference Between AM and FM Radio?” National Inventors Hall of Fame. Aug, 16, 2023. https://www.invent.org/blog/trends-stem/difference-between-am-fm See omnystudio.com/listener for privacy information.

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

We're traveling back to the 1930s Mississippi Delta with Sinners! Join us as we learn about fake plantation money, "Rocky Road to Dublin", Chinese-American communities in Mississippi, hoodoo, and more! Sources: John Jung, "Chinese for the South: Mississippi Delta Chinese Migration Chains," in Zhang, Wenxian, et al. Far East, Down South: Asians in the American South. Tuscaloosa: The University of Alabama Press, 2016. https://muse.jhu.edu/book/49183. "Shaolu Yu, ""Placing Racial Triangulation, Triangulating Place and Race: Chinese Grocery Stores in the Mississippi Delta during the Jim Crow Era,"" Annals of the American Association of Geographers, 112(1) 2022, pp. 97–122" Karin Lurvink, "Strapped for Cash: Non-cash Payments on Louisiana Cotton Plantations, 1865-1908," TIJDSCHRIFT VOOR SOCIALE EN ECONOMISCHE GESCHIEDENIS 11, 3 (2014) Sonny Albarado, "The violent and racist fight against laborers' basic rights in the South," Arkansas Advocate, 2023 Katrina Hazzard-Donald, Mojo Workin': The Old African-American Hoodoo System (University of Illinois Press, 2013).  Cierra Black, "Sinners Hoodoo Consultant Talks Working with Ryan Coogler & Protecting Black Spirituality On-Screen: 'Blues Is the Music of Hoodoo'" Teen Vogue 3 May 2025.  Marcelitte Failla, ""You Deserve, Baby!": Spiritual Co-creation, Black Witches, and Feminism," The Witch Studies Reader 75-89 (Duke University Press, 2025). https://www.jstor.org/stable/jj.25003747.9  Kinitra D. Brooks, "Haints, Hollers, and Hoodoo," Southern Cultures 29:4 (2023): 2-7. Zora Hurston, "Hoodoo in America," The Journal of American Folklore 44:174 (1931): 317-417. https://www.jstor.org/stable/535394  "The Rocky Road to Dublin" in Will Carleton, Will Carleton's "Dandy Pat Songster (1866). https://www.google.com/books/edition/Will_Carleton_s_Dandy_Pat_Songster/ULo-AQAAMAAJ?hl=en&gbpv=1&dq=%22Rocky%20Road%20to%20Dublin%22&pg=PA59&printsec=frontcover  The Citizen (1842), https://www.google.com/books/edition/The_Citizen/VYdPAQAAMAAJ?hl=en&gbpv=1&dq=%22Rocky%20Road%20to%20Dublin%22&pg=PA262&printsec=frontcover  https://www.google.com/books/edition/Diprose_s_Standard_Song_Book_and_Reciter/jzJYAAAAcAAJ?hl=en&gbpv=1&dq=Rocky%20Road%20to%20Dublin&pg=PA24&printsec=frontcover "The Rocky Road to Dublin," in The New Singer's Journal (1871) https://www.google.com/books/edition/Henry_De_Marsan_s_New_Comic_and_Sentimen/3Lk_AQAAMAAJ?hl=en&gbpv=1&dq=%22Rocky%20Road%20to%20Dublin%22&pg=PA175&printsec=frontcover  The rocky road to Dublin. Image. https://www.loc.gov/item/amss-as111860/  "Along the Rocky Road to Dublin" (1915) https://egrove.olemiss.edu/sharris_c/92/  D Taylor, "'Champagne Charlie is my name': The swell, the Irish and the cockney," in From Mummers to Madness (2021).  Michael Pierse, ""A Pole of Differentiation": Pasts and Futures in Irish Working-Class Writing," Working-Class Literature(s): Historical and International Perspectives (2020).  "The Schools' Collection" folklore collected by students in Ireland from 1937-1939 https://www.duchas.ie/en/cbes/stories?SearchText=blackthorn&SearchLanguage=ga&Page=1&PerPage=20 https://www.myirishjeweler.com/blog/irish-folklore-the-blackthorn-and-fairies-fighting-and-harry-potter/?srsltid=AfmBOoqlYcrE-xW106rf2XlffXUu-8oyNtkuISgfqsRmUOsNFEh0g9RU  RT: https://www.rottentomatoes.com/m/sinners_2025  Richard Brody, ""Sinners" is a Virtuosic Fusion of Historical Realism and Horror," April 17, 2025 The New Yorker https://www.newyorker.com/magazine/2025/04/28/sinners-movie-review  Wiki: https://en.wikipedia.org/wiki/Sinners_(2025_film) https://en.wikipedia.org/wiki/First-dollar_gross 

In this fan favorite episode of the podcast, Dr. Bray answers a listener's question on loneliness.  Tune in to learn about the neuroscience and psychology of loneliness, what happens in the brain, and specific action steps you can take to combat loneliness.  In a world where loneliness is increasing exponentially, it is important to understand this issue and notice the signs and warning markers of isolation.  If you want to learn more, see below for specific research into the topics Dr. Bray discussed on this episode. “Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies” by Nicole K Valtorta et al. Heart “Loneliness matters: a theoretical and empirical review of consequences and mechanisms. Annals of Behavioral Medicine” by Louise C. Hawkley et al. Annals of Behavioral Medicine “The growing problem of loneliness” by Cacioppo & Cacioppo. The Lancet “Brain structure links loneliness to social perception” by Ryota Kanai et al. Current Biology “The association between social relationships and depression: a systematic review” by Ziggi Ivan Santini et al. Journal of Affective Disorders “The neuroendocrinology of social isolation” by John Cacioppo et al. Annual Review of Psychology “Social media use and perceived social isolation among young adults in the US” by Brian A. Primack et al. American Journal of Preventative Medicine “A meta-analysis of interventions to reduce loneliness” by Christopher M. Masi et al. Personality and Social Psychology Review “Mindfulness training reduces loneliness and increases social contact in a randomized controlled trial” by Emily K. Lindsay et al. PNAS QUOTES BY DR. BRAY “Loneliness can creep in no matter how connected we may appear or seem to be.” “The key to perception is understanding.” “Social media never replaces personal connection.”  

Honorary third host of the podcast Kaylee is back this week to join us in discussing the R.J. Hackett, a vessel that changed the way bulk cargo was transported on the Great Lakes and laid the groundwork for the designs we still see today. gazafunds.comSources: Baker, Newton D. “Transportation on the Great Lakes.” The Annals of the American Academy of Political and Social Science, vol. 171, Jan 1934, pp. 204 - 210. Bowlus, Bruce. “Bold Experiments: The Evolution of the Great Lakes Ore Carrier.” Michigan Historical Review, vol. 22, no. 1, Spring 1996, pp. 1 - 17. “Steamer Hackett Burns.” The Sturgeon Bay Advocate, vol. 44, no. 34, 18 Nov 1905. Support the show

This new series will be a collaboration between BTK and Annals of Surgery, where we will be discussing hot topics in surgery research. No, we won't be getting into the nitty gritty of methods of individual papers but rather will focus on high-level discussions of contemporary topics that are moving our field forward. Hosts: Cody Mullens, MD is a general surgery resident at the University of Michigan, current Behind the Knife Surgery Education Fellow. (@Cody_Mullens) Justin B. Dimick, MD MPH is the Fredrick A Coller Distinguished Professor and Chair of Surgery at the University of Michigan. He also serves as the Editor in Chief at Annals of Surgery. (@jdimick1) Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://app.behindtheknife.org/listen