Podcasts about Annals

You use ketamine. I use ketamine. We all use ketamine. But… how safe it is, really? A new study out of Toronto suggests 30% of patients who receive ketamine have adverse events, a rate higher than seen in the ED. What are we to make of this? I bring Dr Remle Crowe on to discuss…Citations:1.     Kwong JL, Verbeek PR, Leong YC, Turner L, Huiskamp M, Drennan IR, Francom S, Ropp S, Cheskes S: Paramedic use of ketamine for severe agitation and violence. Can J Emerg Med. doi: 10.1007/s43678-025-00963-w (Epub ahead of print).2.     Fernandez AR, Bourn SS, Crowe RP, Bronsky ES, Scheppke KA, Antevy P, Myers JB: Out-of-Hospital Ketamine: Indications for Use, Patient Outcomes, and Associated Mortality. Annals of Emergency Medicine. 2021;78(1):123–31.3.     Brown LH, Crowe RP, Pepe PE, Miller ML, Watanabe BL, Kordik SS, Wampler DA, Page DI, Fernandez AR, Bourn SS, et al.: Adverse events following emergent prehospital sedation of patients with behavioral emergencies: A retrospective cohort study. The Lancet Regional Health - Americas. 2022;May;9:100183.

Mast cell activation syndrome (MCAS) is a confusing and often misunderstood condition. If you've ever wondered about MCAS symptoms, serum tryptase testing, or how treatments like antihistamines, sodium cromolyn, and even omalizumab fit in, this episode is here to help. We review the findings from “Management of indolent mastocytosis and mast cell activation syndrome - A clinical yardstick,” published in June 2025 in The Annals of Allergy, Asthma & Immunology. Because the paper covers both diseases, we've split it into two parts. This episode focuses on mast cell activation syndrome (MCAS). GET THE INFOGRAPHIC - summary of this episode What we cover in our episode about mast cell activation syndrome: Yardsticks explained: Why the ACAAI uses yardsticks as practical, interim guidelines before full consensus statements are available. Classifying mast cell disorders: Primary (clonal), secondary (allergy/autoimmune), and idiopathic (MCAS). MCAS diagnosis criteria: Symptoms in 2 or more organ systems, objective evidence (serum tryptase or urinary metabolites tests), and positive response to therapy. Treatment strategies: Include trigger avoidance, H1/H2 antihistamines, leukotriene blockers, mast cell stabilizers (such as cromolyn and aspirin), off-label biologics like omalizumab, and epinephrine. Neuropsychiatric symptoms: Brain fog, anxiety, and depression are common and require multidisciplinary management. The Itch Review, hosted by Dr. Gupta, Kortney, and Dr. Blaiss, explores allergy and immunology studies, breaking down complex research in conversations accessible to clinicians, patients, and caregivers. Each episode provides key insights from journal articles and includes a one-page infographic in the show notes for easy reference. Made in partnership with The Allergy & Asthma Network. Thanks to Blueprint Medicines for sponsoring today's episode.  This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

A silent danger lurks within the descending thoracic aorta. While most Type B aortic dissections are managed medically, up to half of these patients will either require life-saving surgery or die within just five years. So how do we separate those who will quietly recover from those on the edge of catastrophe? How do we protect the spinal cord, bowel, and limbs from the devastating consequences of malperfusion? Join the University of Michigan Department of Vascular Surgery as they tackle the high-stakes decisions behind managing this unpredictable disease—where timing is critical, interventions are evolving, and lives hang in the balance. Hosted by the University of Michigan Department of Vascular Surgery: ·       Robert Beaulieu, Program Director ·       Frank Davis, Assistant Professor of Surgery ·       Luciano Delbono, PGY-5 House Officer ·       Andrew Huang, PGY-4 House Officer ·       Carolyn Judge, PGY-2 House Officer Learning Objectives: 1.         Discuss general approach to diagnosis and management of TBAD. 2.         Identifying high-risk features in uncomplicated TBAD and understanding their role in determining the need for surgical management. 3.         Review endovascular techniques for managing malperfusion of the limbs, viscera, and spinal cord and discuss associated decision making. References:  Authors/Task Force Members, Czerny, M., Grabenwöger, M., Berger, T., Aboyans, V., Della Corte, A., Chen, E. P., Desai, N. D., Dumfarth, J., Elefteriades, J. A., Etz, C. D., Kim, K. M., Kreibich, M., Lescan, M., Di Marco, L., Martens, A., Mestres, C. A., Milojevic, M., Nienaber, C. A., … Hughes, G. C. (2024). EACTS/STS Guidelines for Diagnosing and Treating Acute and Chronic Syndromes of the Aortic Organ. The Annals of Thoracic Surgery, 118(1), 5–115. https://doi.org/10.1016/j.athoracsur.2024.01.021 de Kort, J. F., Hasami, N. A., Been, M., Grassi, V., Lomazzi, C., Heijmen, R. H., Hazenberg, C. E. V. B., van Herwaarden, J. A., & Trimarchi, S. (2025). Trends and Updates in the Management and Outcomes of Acute Uncomplicated Type B Aortic Dissection. Annals of Vascular Surgery, S0890-5096(25)00004-4. https://doi.org/10.1016/j.avsg.2024.12.060 Eidt, J. F., & Vasquez, J. (2023). Changing Management of Type B Aortic Dissections. Methodist DeBakey Cardiovascular Journal, 19(2), 59–69. https://doi.org/10.14797/mdcvj.1171 Lombardi, J. V., Hughes, G. C., Appoo, J. J., Bavaria, J. E., Beck, A. W., Cambria, R. P., Charlton-Ouw, K., Eslami, M. H., Kim, K. M., Leshnower, B. G., Maldonado, T., Reece, T. B., & Wang, G. J. (2020). Society for Vascular Surgery (SVS) and Society of Thoracic Surgeons (STS) reporting standards for type B aortic dissections. Journal of Vascular Surgery, 71(3), 723–747. https://doi.org/10.1016/j.jvs.2019.11.013 MacGillivray, T. E., Gleason, T. G., Patel, H. J., Aldea, G. S., Bavaria, J. E., Beaver, T. M., Chen, E. P., Czerny, M., Estrera, A. L., Firestone, S., Fischbein, M. P., Hughes, G. C., Hui, D. S., Kissoon, K., Lawton, J. S., Pacini, D., Reece, T. B., Roselli, E. E., & Stulak, J. (2022). The Society of Thoracic Surgeons/American Association for Thoracic Surgery Clinical Practice Guidelines on the Management of Type B Aortic Dissection. The Annals of Thoracic Surgery, 113(4), 1073–1092. https://doi.org/10.1016/j.athoracsur.2021.11.002 Papatheodorou, N., Tsilimparis, N., Peterss, S., Khangholi, D., Konstantinou, N., Pichlmaier, M., & Stana, J. (2025). Pre-Emptive Endovascular Repair for Uncomplicated Type B Dissection—Is This an Option? Annals of Vascular Surgery, S0890-5096(25)00007-X. https://doi.org/10.1016/j.avsg.2025.01.003 Trimarchi, S., Gleason, T. G., Brinster, D. R., Bismuth, J., Bossone, E., Sundt, T. M., Montgomery, D. G., Pai, C.-W., Bissacco, D., de Beaufort, H. W. L., Bavaria, J. E., Mussa, F., Bekeredjian, R., Schermerhorn, M., Pacini, D., Myrmel, T., Ouzounian, M., Korach, A., Chen, E. P., … Patel, H. J. (2023). Editor's Choice - Trends in Management and Outcomes of Type B Aortic Dissection: A Report From the International Registry of Aortic Dissection. European Journal of Vascular and Endovascular Surgery: The Official Journal of the European Society for Vascular Surgery, 66(6), 775–782. https://doi.org/10.1016/j.ejvs.2023.05.015 Writing Committee Members, Isselbacher, E. M., Preventza, O., Hamilton Black Iii, J., Augoustides, J. G., Beck, A. W., Bolen, M. A., Braverman, A. C., Bray, B. E., Brown-Zimmerman, M. M., Chen, E. P., Collins, T. J., DeAnda, A., Fanola, C. L., Girardi, L. N., Hicks, C. W., Hui, D. S., Jones, W. S., Kalahasti, V., … Woo, Y. J. (2022). 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Journal of the American College of Cardiology, 80(24), e223–e393. https://doi.org/10.1016/j.jacc.2022.08.004 Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://app.behindtheknife.org/listen

What does “great” Medical Affairs look like in 2025? We talk evidence, access, patient voice, and how to work with Commercial without crossing the promotional line. Abdul Hameed Al-Khateeb, Country Medical Director, shares practical lessons on measurement, real-world evidence, and where AI actually helps.Email to your listSubject line options (pick one):Inside Medical Affairs: From Evidence to AccessThe Missing Link Between Science and PatientsWhat Great Medical Affairs Looks Like (and How to Measure It)

Why do so many women struggle with stress-related health issues without ever speaking up? In this episode, Dr. Brendan McCarthy continues his series on self-silencing in women—a powerful yet often overlooked cultural and psychological pattern. Dr. McCarthy breaks down: What “self-silencing” really means and how it shows up in everyday life The four categories of self-silencing How chronic stress and emotional suppression affect hormones, fertility, and cardiovascular health Why women face higher risks of heart disease when these patterns go unaddressed What men can do to better support their partners during PMS, perimenopause, and menopause   This conversation is about more than symptoms—it's about validation, advocacy, and the urgent need to recognize how cultural conditioning impacts women's health.   Citations: Jack, D. C., & Dill, D. (1992). The Silencing the Self Scale: Schemas of intimacy associated with depression in women. Psychology of Women Quarterly, 16(1), 97–106.       •     Jack, D. C. (1999). Silencing the self: Inner dialogues and outer realities. Harvard University Press.       •     Jack, D. C. (2011). Reflections on the silencing the self scale and its origins. Psychology of Women Quarterly, 35(3), 523–529.       •     Jakubowski, K. P., Barinas-Mitchell, E., et al. (2022). The cardiovascular cost of silence: Self-silencing and carotid atherosclerosis. Annals of Behavioral Medicine, 56(3), 282–293.       •     Ussher, J. M. (2004). Premenstrual syndrome and self-policing. Social Theory & Health, 2(1), 56–77.       •     Ussher, J. M. (2013). Diagnosing difficult women. Feminism & Psychology, 23(1), 63–77.       •     Beauboeuf-Lafontant, T. (2008). Listening past the lies. Qualitative Sociology, 31(2), 105–124.       •     Rozanski, A. (2014). Behavioral cardiology. Circulation, 129(25), 2509–2516. 1.    Jack & Dill (1992) – Developed Silencing the Self Scale. Linked to depression and poor health outcomes.       2.    Framingham Offspring Study (Jack, 2011) – Women with high self-silencing had ↑ heart disease and premature death.       3.    Jakubowski et al. (2022, Annals of Behavioral Medicine) – Self-silencing predicted ↑ carotid atherosclerosis in midlife women.       4.    Beauboeuf-Lafontant (2008, Qualitative Sociology) – Black women's depression tied to silencing under cultural expectations of strength.       5.    Ussher (2004, 2013, 2023) – Purity/self-policing associated with self-blame and somatic illness pathways.       6.    Rasmussen (2014) – Self-silencing linked to anger suppression, leading to somatic symptoms.       7.    Peterson (2015) – Shame and silence in purity narratives obstruct preventive health care.       8.    CRP & Stress Studies – High CRP consistently linked to psychosocial stress (Rozanski, 2014, Circulation).   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.  

We've covered pre-oxygenation strategies and intubation alot on this podcast, mayber more than anyting else. We covered the definition of FPS in E74, the DEVICE trial on DL vs VL in E75, and the PREOXI trial of NIV vs Mask Pre-oxygenation in E86. Now we have another Preoxygenation paper, this one that reports no difference between preoxygenation with BVM and face mask. WTAF? Better listen, because it turns out words matter, definitions are... definitional, and we absolutely MUST read more than just the abstract.  Citations:1.     Gottlieb M, Alexander R, Love AK: Comparison of Preoxygenation Strategies for Intubation of Critically Ill Patients. Annals of Emergency Medicine. doi: 10.1016/j.annemergmed.2025.06.621 (Epub ahead of print).2.     Chou CD, Palakshappa JA, Haynie H, Garcia K, Long D, Gibbs KW, White HD, Ghamande S, Dagan A, Stempek S, et al.: Association of Two Preoxygenation Approaches With Hypoxemia During Tracheal Intubation: A Secondary Analysis. Annals of Emergency Medicine. doi: 10.1016/j.annemergmed.2025.06.003 (Epub ahead of print).3.     Pitre T, Liu W, Zeraatkar D, Casey JD, Dionne JC, Gibbs KW, Ginde AA, Needham-Nethercott N, Rice TW, Semler MW, et al.: Preoxygenation strategies for intubation of patients who are critically ill: a systematic review and network meta-analysis of randomised trials. The Lancet Respiratory Medicine. 2025;July;13(7):585–96.4.     Gibbs KW, Semler MW, Driver BE, Seitz KP, Stempek SB, Taylor C, Resnick-Ault D, White HD, Gandotra S, Doerschug KC, et al.: Noninvasive Ventilation for Preoxygenation during Emergency Intubation. N Engl J Med. doi: 10.1056/NEJMoa2313680 (Epub ahead of print).5.     Prekker ME, Driver BE, Trent SA, Resnick-Ault D, Seitz KP, Russell DW, Gaillard JP, Latimer AJ, Ghamande SA, Gibbs KW, et al.: Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults. N Engl J Med. 2023;June 16;389(5):418–29.6.     Trent SA, Kaji AH, Carlson JN, McCormick T, Haukoos JS, Brown CA, National EARI: Video Laryngoscopy is Associated With First-Pass Success in Emergency Department Intubations for Trauma Patients: A Propensity Score Matched Analysis of the National Emergency Airway Registry. Ann Emerg Med. doi: 10.1016/j.annemergmed.2021.07.115 (Epub ahead of print).

If you read the Annals of Tigernach, you will find that Máel Brigte mac Mothlachán killed Rogallach mac Uatach, King of Connacht, in battle, because the Uí Briúin tribe had been encroaching on the territory of the Corco Cullu, and so it was one of those normal murders. However, if you read the renowned and beloved Geoffrey Keating, you will discover that no, Rogallach, riding his white horse, was killed by servants, after a dispute about who had actually killed a deer, but before that Rogallach had been living a version of Oedipus, sleeping with his daughter, who had been, as an infant sent out to die, but a huntsman saved her, and then later her dad met her and incestuous relations followed. We do talk about Connacht, and Rogallach, and Máel Brigte mac Mothlachán, but really what Anne is concerned about is the inability of some historians to tell the difference between history and storytelling, and Michelle, bless her heart, is driven to sputtering outrage by the inability of some scholars to tell you where they found the stuff, history or story, either one.

Qianlong's empire shines as a beacon of both martial might and cultural splendor, yet its mirrored glory hides truths too fragile for celestial ambitions. Time Period Covered: ~1770-1799CE Major Historical Figures: Qing Empire: The Qianlong Emperor (Aisin-Gioro Hongli) [r. 1735–1796, d. 1799] Grand Councillor Heshen [1750-1799] Great Britain: Lord George Macartney (1737-1806) Major Sources Cited: Bland, J.O.P. and Lord Edmund Backhouse. Annals and Memoirs of the Court at Peking. Fairbank, John King, and Denis Twitchett, eds. The Cambridge History of China, Volume 9, Part 1: The Ch'ing Empire to 1800. Perdue, Peter. China Marches West: The Qing Conquest of Central Eurasia. Woodside, Alexander. The Qing in the Age of Confucian Empire. Yuan, Wei. Shengwu ji (Sacred Military Achievements). Learn more about your ad choices. Visit megaphone.fm/adchoices

US Health Secretary RFK Jr's call to retract a study on childhood vaccines is resisted by the journal. Also antibiotics get designed by AI, and a new way for stars to die. A study focussing on Danish childhood vaccination data has attracted the US Secretary for Health's anger, as RFK jr calls for the journal in which it was published, the Annals of Internal Medicine, to retract it. The Editor, Christine Laine, talk to Science in Action about the strengths and challenges of observational studies. The cuts to prestigious US federal science funded research continue, as last week it was announced that $500 million funding for future mRNA vaccines would be withdrawn. Barney Graham, one of the pioneers in the field and prominent during the Covid vaccines, argues that the research will still happen, though maybe not in the US, as mRNA has become a fundamental area of global research. Meanwhile, strides are being made in the field of synthetic biology as Jim Collins and colleagues at MIT and Harvard have used AI to design potentially viable antibiotics for two important drug-resistant superbugs. Previously, AI has been used to comb through libraries of known antibiotics. This study has gone a step further, and used generative AI to design new ones, that can then be synthesised using real chemicals. Though a long way from being prescribable drugs, the team think this could herald a new golden age of antibiotic development – something which has been lacking in recent decades. Finally, it seems astronomers may have discovered a new way for a star to die, sort of. Supernova 2023zkd was seen to explode back in 2023, found by a team looking for odd events. It didn't seem quite like normal supernovae, in that it took a bit longer to die down. Then the team looked back, and noticed that it had also been getting slowly brighter for almost a year. At 730 million light years away, in a galaxy far, far away, it also seemed to have been stripped of all its hydrogen and even stranger yet, appeared to have exploded twice. As Ashley Villar of the Harvard Smithsonian Center for Astrophysics explains, the almost unique observation fits with a model of the huge star getting closer to a black hole, the gravity of which may have disrupted the star enough to cause it to explode. Presenter: Roland Pease Producer: Ella Hubber with Alex Mansfield Production Coordinator: Jana Bennett-Holesworth (Image: Child getting a vaccine. Credit: Luis Alvarez via Getty Images)

Vinay Prasad is back at the FDA as chief of the FDA's Center for Biologics Evaluation and Research. Prasad's return—which hit the news wires Saturday morning—came just 10 days after his unexpected exit on July 29, following blowback over the saga involving Sarepta Therapeutics' Duchenne muscular dystrophy gene therapy Elevidys, and a campaign by conversative personalities to oust the outspoken physician.Elsewhere in the government, Gray Delany, former head of HHS' and President Donald Trump's Make America Healthy Again agenda, has been fired—days after Health and Human Services Secretary Robert F. Kennedy Jr. axed 22 mRNA vaccine contracts under the Biomedical Advanced Research and Development Authority. Delany's ouster came after he allegedly butted heads with other agency officials over how announcements were made, according to reporting from Endpoints News. The mRNA contract cuts, meanwhile, have sparked criticism from the scientific community and concern that the growing anti-mRNA sentiment could also have a negative effect on research for cancer therapeutics.In somewhat related news, the Annals of Internal Medicine is refusing to retract a large-scale study it ran in July that pointed to the lack of an association between childhood aluminum exposure through vaccination and chronic conditions, despite Kennedy's criticism. In an op-ed published earlier this month, the Health Secretary took issue with the study's design.In obesity news, biopharma darling Eli Lilly suffered a rare chink in its normally impenetrable GLP-1 armor. The first Phase III trial for oral weight loss therapy orforglipron read out last week, and the results were underwhelming, at least to Wall Street. Truist Securities wrote that the data support approval but “leaves room for competition.” This is good news for a whole host of companies, including Roche, Viking, Terns and Rhythm Pharmaceuticals, who all have weight loss pills at various stages of development.And in gene therapy, the hits just keep coming. The FDA has limited the use of bluebird bio's gene therapy Skysona to patients with cerebral adrenoleukodystrophy for whom no other therapies or stem cell donors are available, due to a heightened risk of blood cancers. This follows safety issues in gene therapy trials experienced by Allogene, and, of course, Sarepta Therapeutics. This week in ClinicaSpace, Dan Samorodnitsky explored the future of AAV technology. And in BioPharm Executive, Annalee Armstrong sat down with Chris Anzalone, CEO of Arrowhead Pharmaceuticals—Sarepta's key strategic partner—to learn how his company has been weathering the storm.

In the July issue of the Annals of Emergency Medicine podcast, Ryan and Rory discuss treatments for agitated delirium in children, albumin for septic shock, and much more.

On this episode, the podcast crew discusses the recent introduction of video laryngoscopy with recording capability at MCHD. What device did you use? How did you train? What lessons have you learned? All these and more will be addressed and answered. REFERENCES: 1. Zhao, Y., Zang, B., & Wang, Q. (2024). The Effectiveness of Bougie Use on First-Attempt Success in Tracheal Intubations. Annals of emergency medicine, 84(3), 331–332. 2. Weingart, S. D., Barnicle, R. N., Janke, A., Bhagwan, S. D., Tanzi, M., McKenna, P. J., Bracey, A., & Resuscitationists Research Group (2023). A taxonomy of key performance errors for emergency intubation. The American journal of emergency medicine, 73, 137–144.

Die Themen in den Wissensnachrichten +++ Forschende aus Kanada beobachten höheres Psychose-Risiko beim Kiffen +++ Thüringer Forschende beanspruchen ältesten Bratwurst-Stand für Erfurt +++ Wenn KI-Antworten zu Salz zur Vergiftung führen +++**********Weiterführende Quellen zu dieser Folge:Cannabis and psychosis. Canadian Medical Association Journal, 11.08.2025Geschichte der Bratwurst. Zeitleiste vom Deutschen Bratwurstmuseum im Mühlhausen/ThüringenA Case of Bromism Influenced by Use of Artificial Intelligence. Annuals of Internal Medicine: Clinical Cases, 05.08.2025Contribution of lake littoral zones to the continental carbon budget. Nature Geoscience, 04.08.2025Global recruitment patterns and placebo responses in clinical trials of rheumatoid arthritis. Annals of the Rheumatic Diseases, 01.08.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Listener feedback on SURPASS CVOT, AF ablation and the limits of meta-analyses, a Watchman alert from FDA, and oral anticoagulation choices in elderly patients are discussed by John Mandola, MD, in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I SURPASS CVOT This Week in Cardiology Podcast, August 1 https://www.medscape.com/viewarticle/1002781 Mounjaro Appears More Heart Protective Than Trulicity in Trial Of Eli Lilly Diabetes Drugs https://www.medscape.com/s/viewarticle/mounjaro-proves-more-heart-protective-than-trulicity-trial-2025a1000kct II Catheter and Surgical AF ablation Catheter and Surgical Ablation for AF: Meta-Analysis https://www.acpjournals.org/doi/10.7326/ANNALS-25-00253 III Watchman Air Embolism Alerts Looming Pay Cut to LAAO Triggers Objection From Card Groups https://www.medscape.com/viewarticle/looming-pay-cut-laao-triggers-objection-card-groups-2025a1000l0j FDA Alert https://www.fda.gov/medical-devices/medical-device-recalls/early-alert-watchman-access-system-issue-boston-scientific IV Switching Oral Anticoagulants in Frail Older Adults Patients FRAIL AF Trial https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.066485 COMBINE AF Substudy https://doi.org/10.1016/j.jacc.2025.05.060 The Most Important Study From ESC: FRAIL-AF https://www.medscape.com/viewarticle/996063 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

Yalnızlık dost mu düşman mı arkadaşlar biri artık şunu açıklasın! Ben şahsen bizzat kendim yalnızım biliyorsunuz ve inanır mısınız bundan da mutluyum. Her ne kadar bazıları yalnızlığı bir sorun, yalnız insanları "bozuk" olarak görseler de bence öyle değil. Peki yalnızlık ne zaman sorun? Yalnızlığın ne kadarı sorun? Sınırı nerden çekicez? Hepsini araştırdım sizin için; yalnızlık dost mu düşman mı BEN bu bölümde açıklıyorum! Kaynakça: 1-Cacioppo, J. T., & Cacioppo, S. (2018). The growing problem of loneliness. The Lancet, 391(10119), 426. https://doi.org/10.1016/S0140-6736(18)30142-9 2-Hawkley, L. C., & Cacioppo, J. T. (2010). Loneliness matters: A theoretical and empirical review of consequences and mechanisms. Annals of Behavioral Medicine, 40(2), 218–227. https://doi.org/10.1007/s12160-010-9210-8 3-Lieberman, M. D., & Eisenberger, N. I. (2009). Pains and pleasures of social life. Science, 323(5916), 890–891. https://doi.org/10.1126/science.1170008 4-Nowland, R., Necka, E. A., & Cacioppo, J. T. (2018). Loneliness and social internet use: Pathways to reconnection in a digital world? Perspectives on Psychological Science, 13(1), 70–87. https://doi.org/10.1177/1745691617713052 5-Nguyen, T. V., Weinstein, N., & Ryan, R. M. (2022). The bright side of solitude: The role of autonomy in positive solitary experiences. Personality and Social Psychology Bulletin, 48(2), 279–293. https://doi.org/10.1177/01461672211014200 6-Shiovitz-Ezra, S., & Ayalon, L. (2012). Situational versus chronic loneliness as risk factors for all-cause mortality. International Psychogeriatrics, 24(3), 440–447. https://doi.org/10.1017/S1041610211001957 7-Rokach, A. (2015). The psychology of solitude: Meaning and experience. Journal of Psychology & Psychotherapy, 5(6). https://doi.org/10.4172/2161-0487.1000203 8-Holt-Lunstad, J., Smith, T. B., Baker, M., Harris, T., & Stephenson, D. (2015). Loneliness and social isolation as risk factors for mortality: A meta-analytic review. Perspectives on Psychological Science, 10(2), 227–237. https://doi.org/10.1177/1745691614568352 9-Layous, K., Nelson, S. K., & Lyubomirsky, S. (2013). What triggers prosocial effort? A test of the empathy–altruism hypothesis. Motivation and Emotion, 37(3), 447–457. https://doi.org/10.1007/s11031-012-9331-7 10-Reading University. (2023). How solitude boosts wellbeing. University of Reading News. Retrieved from https://www.reading.ac.uk/news/2023/Research-News/How-solitude-boosts-wellbeing 11-New York Post. (2025). 3 major benefits of being alone, according to a psychologist. Retrieved from https://nypost.com/2025/04/13/health/3-major-benefits-of-being-alone-according-to-a-psychologist ------- Podbee Sunar ------- Bu podcast, Garanti BBVA reklamı içermektedir. Bonus Platinum'un avantajlarını keşfet!

Welcome to the first episode in a five-part series on self-silencing and its profound effect on women's health. I'm Dr. Brendan McCarthy, Chief Medical Officer at Protea Medical Center, and in this episode, I break down how self-silencing — the learned suppression of one's needs, emotions, and voice — directly influences weight gain, hormone disruption, autoimmunity, cardiovascular risk, and more. This is a deeply personal and evidence-backed conversation rooted in decades of clinical experience and medical research. I discuss real patient patterns, the emotional layers behind common health complaints, and why this silent epidemic deserves more space in medicine. If you or someone you love has ever struggled with feeling unheard, unseen, or overwhelmed by caretaking roles, this is for you.   Citations: 13] Jakubowski, K. P., Barinas-Mitchell, E., Chang, Y.-F., Maki, P. M., Matthews, K. A., & Thurston, R. C. (2021). The Cardiovascular Cost of Silence: Relationships Between Self-silencing and Carotid Atherosclerosis in Midlife Women. *Annals of Behavioral Medicine, 56*(3), 282–290. DOI: 10.1093/abm/kaab046 [27] Eyal, M. (2023, October 3). Self-Silencing Is Making Women Sick. *TIME*. [5] Jack, D. C. (2010, March 29). Silencing the Self Theory. *OUPblog*.   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.  

16th-century Swiss physician Paracelsus was frustrated with established medical practice and academia and he was sometimes on the lam because of his beliefs. He wrote at length about the idea that items in the natural world carried “signatures” in their appearance that could tell you visually how they could be used medicinally. Research: Bennett, B.C. Doctrine of Signatures: An explanation of medicinal plant discovery or Dissemination of knowledge?. Econ Bot 61, 246–255 (2007). https://doi.org/10.1663/0013-0001(2007)61[246:DOSAEO]2.0.CO;2 Dafni, Amots, and E. Lev. “The Doctrine of Signatures in Present-Day Israel.” Economic Botany, vol. 56, no. 4, 2002, pp. 328–34. JSTOR, http://www.jstor.org/stable/4256605 “The Doctrine Of Signatures.” The British Medical Journal, vol. 1, no. 627, 1873, pp. 19–19. JSTOR, http://www.jstor.org/stable/25233757 “The Doctrine of Signatures.” John Moore Museum. May 11, 2021. https://www.johnmooremuseum.org/the-doctrine-of-signatures/ The Editors of Encyclopaedia Britannica. "laudanum". Encyclopedia Britannica, 19 Jul. 2025, https://www.britannica.com/science/laudanum The Editors of Encyclopaedia Britannica. "Peasants’ War". Encyclopedia Britannica, 20 Aug. 2020, https://www.britannica.com/event/Peasants-War Grzybowski, Andrzej and Katarzyna Pawlikowska-Łagód. “Some lesser-known facts on the early history of syphilis in Europe.” Clinics in Dermatology. Volume 42, Issue 2. 2024. Pages 128-133. https://doi.org/10.1016/j.clindermatol.2023.12.003. Hargrave, John G. "Paracelsus". Encyclopedia Britannica, 3 Jul. 2025, https://www.britannica.com/biography/Paracelsus “The history of syphilis part two: Treatments, cures and legislation.” Science Museum UK. Nov. 8, 2023. https://www.sciencemuseum.org.uk/objects-and-stories/history-syphilis-part-two-treatments-cures-and-legislation Kikuchihara, Y., Hirai, H. (2015). Signatura Rerum Theory. In: Sgarbi, M. (eds) Encyclopedia of Renaissance Philosophy. Springer, Cham. https://doi.org/10.1007/978-3-319-02848-4_405-1 Lund, F B. “PARACELSUS.” Annals of surgery vol. 94,4 (1931): 548-61. doi:10.1097/00000658-193110000-00009 Michaleas, Spyros N et al. “Theophrastus Bombastus Von Hohenheim (Paracelsus) (1493-1541): The eminent physician and pioneer of toxicology.” Toxicology reports vol. 8 411-414. 23 Feb. 2021, doi:10.1016/j.toxrep.2021.02.012 Paracelsus. “Of the supreme mysteries of nature. : Of the spirits of the planets. of occult philosophy. The magical, sympathetical, and antipathetical cure of wounds and diseases. The mysteries of the twelve signs of the zodiack.” London. 1656. Accessed online: https://archive.org/details/paracelsvsofsupr00para/page/n9/mode/2up Simon, Matt. “Fantastically Wrong: The Strange History of Using Organ-Shaped Plants to Treat Disease.” Wired. July 16, 2014. https://www.wired.com/2014/07/fantastically-wrong-doctrine-of-signatures/ Tampa, M. et al. “Brief history of syphilis.” Journal of medicine and life vol. 7,1 (2014): 4-10.https://pmc.ncbi.nlm.nih.gov/articles/PMC3956094/#R6 Waite, Arthur Edward. “Lives of alchemystical philosophers based on materials collected in 1815 : and supplemented by recent researches with a philosophical demonstration of the true principles of the magnum opus, or great work of alchemical re-construction, and some account of the spiritual chemistry.” London. G. Redway. 1888. Accessed online: https://archive.org/details/livesofalchemyst1888wait See omnystudio.com/listener for privacy information.

Most Americans hardly knew about autism in the 1980s and '90s. Then, as if suddenly, autism became big news in the 2000s. And the rate of autism has increased since, including diagnosis among adults. But how did this happen?

Hosts Pastor Robert Baltodano and Pastor Lloyd Pulley Question Timestamps: Load Hauler, YouTube (3:26) - What happened to the Book of the Annals? Have they been recovered? Denise, Facebook (4:29) - Can you clarify the angel telling Mary to name the baby "Immanuel," and then they named him "Jesus?" Carlos, NJ (6:43) - Can you clarify 1 Thessalonians 4:13-18 versus Luke 16? Maritza, email (11:12) - What will we be judged for, or have to give an account for, if all our sins are forgiven? Jaysha, NJ (14:24) - Is it true that Satan was once an angel, and is now a fallen angel? Is that why we all fall short and Jesus had to die on the cross? Joyce, email (16:41) - What are your thoughts on the Geneva Bible? Did King James change the Bible? Cleveland, VA (20:36) - What was the shedding of blood given for the remission of Adam's sin? Wendy, NJ (22:01) - When does the story of the sheep and the goats in Matthew 25 take place, before or after the Millennial Kingdom? Who is it about? Levi, NY (26:10, continued after break at 33:33) - Didn't Eve sin first? Lena, NY (37:18) - Can God destroy? Does He destroy completely? Calvary Young Adults Q&A (46:19) - How should I be preparing to be a faithful and submissive wife? George, TX (50:29) - How do I revitalize my wife's faith? Ask Your Question: 888-712-7434 Answers@bbtlive.org

Reference: Bourke EM, et al. PEAChY-O: Pharmacological Emergency Management of Agitation in Children and Young People: A Randomized Controlled Trial of Oral Medication. Annals of Emergency Medicine. Feb 2025 Date: April 29, 2025 Guest Skeptic: Dr. Brad Sobolewski, is a pediatric emergency medicine physician at Cincinnati Children's Hospital and Professor of Pediatrics at the University […] The post SGEM#480: In the End It Doesn't Even Matter: Oral Olanzapine or Diazepam for Pediatric Agitation first appeared on The Skeptics Guide to Emergency Medicine.

Por Yaiza Santos Le llevó un buen rato analizar el sintagma «memoria democrática» para comentar lo que el Gobierno ha ordenado hacer con la jefatura de Policía de Vía Layetana. Bien sabe él que no son más que las migajas a las que está obligado Sánchez para alimentar a los nacionalistas si quiere permanecer en el poder los años que le quedan, pero no quiso dejar de proponer una resignificación –como dicen– de la resignificación. Nadie niega que en ese edificio se cometieran actos indignos contra la humanidad, y que desde allí se trazaran estrategias para que la libertad y la dignidad florecieran en nuestro país. Pero eso no fue lo único que ocurrió en él. Desde allí, también, honrados empleados del Estado trabajaron en la defensa de la democracia en España, por ejemplo contra el terrorismo. Y no digamos el papel que tuvieron en el infausto 1 de octubre, cuando fueron los únicos funcionarios que cumplieron con su obligación. ¡Democrática! Así pues, propone que al lado de la plaquita que coloquen sobre las torturas del franquismo, que pongan una también recordando a los héroes de la Vía Layetana. Qué cansado está del horóscopo de la Aemet, que tiene en alerta roja a Barcelona por una tormenta de verano. Lo tiene dicho: no puede ser ese rojo el mismo que el de la trágica dana, porque entonces se estará atentando contra la seguridad. Sigue con mucha atención las crónicas del valet de chambre Cué y ciertamente se alegra de que el presidente esté fuerte y esté bien. ¡Al menos hasta el próximo informe de la UCO! La degradación a la que los políticos someten la esfera pública no debe confundirnos, advirtió a Santos: bien está que el jefe del Ejecutivo y su mujer viajen en Falcon adonde necesiten. Expresó su interés por el caso Epstein y el papel de Trump y, como de costumbre, apostilló un nuevo paper candente: cuando un hallazgo científico nos parece moralmente ofensivo... lo atacamos como si fuera una amenaza personal. ¡Humano, muy humano! Y fue así que Espada yiró.Bibliografía Cory Clark et al., «Los hallazgos científicos moralmente ofensivos activan la charlatanería cognitiva», Annals of the New York Academy of Sciences, 8 de junio de 2025See omnystudio.com/listener for privacy information.

Send us a textRiley's doctor recommended bariatric surgery as the solution to their health concerns, but when Riley came to me for advice, I realized they hadn't been told about the real risks. From anastomosis leaks with 15% mortality rates to spontaneous bowel perforations years later, the complications of weight loss surgery extend far beyond what most patients are counseled about. In this episode, I walk through the evidence-based risks that every patient deserves to know before making this life-altering decision, because informed consent requires the whole truth. If you or someone you know is considering weight loss surgery, then be sure to send them a link to this episode!References:Lim, Robert et al. “Early and late complications of bariatric operation.” Trauma surgery & acute care open vol. 3,1 e000219. 9 Oct. 2018Silva, Ana Flávia da et al. “Risk factors for the development of surgical site infection in bariatric surgery: an integrative review of literature.” Revista latino-americana de enfermagem vol. 31 (2023)Complications of bariatric surgery: presentation and emergency management--a review.” Annals of the Royal College of Surgeons of England vol. 91,4 (2009): 280-6.Benotti, Peter et al. “Risk factors associated with mortality after Roux-en-Y gastric bypass surgery.” Annals of surgery vol. 259,1 (2014): 123-30. Coupaye, Muriel et al. “Evaluation of incidence of cholelithiasis after bariatric surgery in subjects treated or not treated with ursodeoxycholic acid.” Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery vol. 13,4 (2017): 681-685 Husain, Syed et al. “Small-bowel obstruction after laparoscopic Roux-en-Y gastric bypass: etiology, diagnosis, and management.” Archives of surgery (Chicago, Ill. : 1960) vol. 142,10 (2007): 988-93 Seeras K, Acho RJ, Lopez PP. Roux-en-Y Gastric Bypass Chronic Complications. [Updated 2023 Jun 5]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK519489/Got a question for the next podcast? Let me know! Connect With Me FREE GUIDES: evidence-based, not diet nonsense NEWSLETTER: Life-changing insights straight to your inbox UNSHRINKABLE: Find out why your body is not designed to shrink MASTERCLASSES: All the evidence doctors should give you NO WEIGH PROGRAM: Join the revolution against weight-loss lies THE WEIGHTING ROOM: A community where authenticity thrives and every voice matters CONSULTATION: For the ultimate transformation in your healthcare journe Find me on Instagram, YouTube, and LinkedIn.

For decades, Alejandro Portes (CASBS fellow 1980-81) has been among our most distinguished scholars elucidating the causes and consequences of immigration and assimilation. René D. Flores (CASBS fellow 2023-24) engages Portes in a conversation spanning large swaths of Portes's formidable intellectual biography, including his personal journey from Cuba and its influence on his academic trajectory, as well as his approach to social science inquiry and its delivery of insights leading to some of his most celebrated and consequential works.ALEJANDRO PORTES: Princeton faculty page | CV | Univ. of Miami faculty page | Wikipedia page | on Google Scholar | Biographical sketches of Portes: American Sociological Association | National Academy of Education | Princeton | National Institutes of Health | Proceedings of the National Academy of Sciences | Robert K. Merton's full quote about Alejandro Portes is contained in the September/October 1998 issue of Footnotes, a publication of the American Sociological Association. Access the full text.  Works referenced in this episodeAlejandro Portes, "Rationality in the Slum: An Essay on Interpretive Sociology," Comparative Studies in Society and History, v13 n3, June 1972.Alejandro Portes, "Dilemmas of a Golden Exile: Integration of Cuban Refugee Families in Milwaukee," American Sociological Review, v34 n4, August 1969.Alejandro Portes and Robert Bach, Latin Journey: Cuban and Mexican Immigrants in the United States. Univ. of California Press, 1985.Alejandro Portes and Min Zhou, "The New Second Generation: Segmented Assimilation and its Variants," Annals of the American Academy of Political and Social Science, November 1993.Alejandro Portes and Ruben Rumbaut, Immigrant America: A Portrait, Univ. of California Press, 2024 (fifth ed.)Alejandro Portes and Ruben Rumbaut, Legacies: The Story of the Immigrant Second Generation, Univ. of California Press, 2001.Jennifer Lee and Min Zhou, The Asian American Achievement Paradox, Russell Sage Foundation, 2015. (Notably, Jennifer Lee was a CASBS fellow in 2002-03; Min Zhou was a CASBS fellow in 2006-06.)Bonus: 2019-20 CASBS fellow Catherine Ramírez discusses the influence of Alejandro Portes in "What Does Assimilation Mean?" Public Books, Feb. 27, 2020. The essay was written as part of CASBS's partnership with Public Books. Ramírez writes, "By showing that there are many strata in society into which people assimilate, and many outcomes of assimilation, Portes and his coauthors have enriched our understanding of the processes by which people become American, however precarious that status may be.” René D. Flores: Univ. of Chicago faculty page | CASBS page | on Google Scholar | Personal website |    Center for Advanced Study in the Behavioral Sciences (CASBS) at Stanford UniversityExplore CASBS: website|Bluesky|X|YouTube|LinkedIn|podcast|latest newsletter|signup|outreach​Human CenteredProducer: Mike Gaetani | Audio engineer & co-producer: Joe Monzel |

Edwin Howard Armstrong isn’t exactly a well-known inventor, but his work in radio literally changed communications around the globe. But his most famous invention – FM radio – became a source of constant frustration after he developed it. Research: Armstrong, Edwin H. “Frequency Modulation and Its Future Uses.” The Annals of the American Academy of Political and Social Science, vol. 213, 1941, pp. 153–61. JSTOR, http://www.jstor.org/stable/1024069 Armstrong, Edwin H. “Personalities in Science.” Scientific American, vol. 154, no. 1, 1936, pp. 3–3. JSTOR, http://www.jstor.org/stable/26144367 “First public radio broadcast.” Guinness World Records. https://www.guinnessworldrecords.com/world-records/381969-first-public-radio-broadcast “FM Inventor Dies in Fall.” The Patriot News. Feb. 2, 1954. https://www.newspapers.com/image/1094174282/?match=1&terms=%22Edwin%20Howard%20Armstrong%22 Lessing, Lawrence P.. "Edwin H. Armstrong". Encyclopedia Britannica, 14 Dec. 2024, https://www.britannica.com/biography/Edwin-H-Armstrong Lessing, Lawrence P. “Man of High Fidelity: Edwin Howard Armstrong.” Bantam. 1969. Lessing, Lawrence P. “The Late Edwin H. Armstrong.” Scientific American, vol. 190, no. 4, 1954, pp. 64–69. JSTOR, http://www.jstor.org/stable/24944524 “Proceedings of the Institute of Radio Engineers, Volume 5.” Institute of Radio Engineers. 1917. Accessed online: https://books.google.com/books?id=YEASAAAAIAAJ&source=gbs_navlinks_s “Radio Broadcast.” Garden City, N.Y.: Doubleday, Page & Co., 1922-1930. https://babel.hathitrust.org/cgi/pt?id=iau.31858044013914&view=1up&seq=277 “Telephoning Without Wires.” The Fort Wayne Journal Gazette. Oct. 20, 1907. https://www.newspapers.com/image/29125618/?match=1&terms=audion%20%22de%20Forest%22 Tsividis, Yannis. “Edwin Armstrong: Pioneer of the Airwaves.” Columbia Magazine. April 1, 2002. https://magazine.columbia.edu/article/edwin-armstrong-pioneer-airwaves Turner, H. M. “Dr. Edwin H. Armstrong, Edison Medalist.” The Scientific Monthly, vol. 56, no. 2, 1943, pp. 185–87. JSTOR, http://www.jstor.org/stable/17796 “What’s the Difference Between AM and FM Radio?” National Inventors Hall of Fame. Aug, 16, 2023. https://www.invent.org/blog/trends-stem/difference-between-am-fm See omnystudio.com/listener for privacy information.

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The historical works of Tacitus are a history of the period from A.D. 14 to 96 in thirty volumes. Although many of the works were lost (only books 1-5 of the Histories and 1-6 and 11-16 of the Annals survive), enough remains to provide a good sense of Tacitus's political and moral philosophy.  He recognized the necessity for strong rulers but argued that more should be done to manage the succession of power and allow for the ascension of talent. Tacitus asserted that it was the dynastic ambitions of Rome's many emperors that caused the decline of moral and political life and precluded the possibility of recruiting leaders of real ability. Moreover, the dynastic temptation caused political instability because military force was now required for political change. His works point to the necessity of systematic institutional restraints on power for the preservation of liberty.  Gordon's translation and his lengthy Discourses on Tacitus bring Tacitus' ideas up to date and apply them to the British state of the early 18th century.  Translated by Thomas Gordon.  This is a collaborative reading.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

We're traveling back to the 1930s Mississippi Delta with Sinners! Join us as we learn about fake plantation money, "Rocky Road to Dublin", Chinese-American communities in Mississippi, hoodoo, and more! Sources: John Jung, "Chinese for the South: Mississippi Delta Chinese Migration Chains," in Zhang, Wenxian, et al. Far East, Down South: Asians in the American South. Tuscaloosa: The University of Alabama Press, 2016. https://muse.jhu.edu/book/49183. "Shaolu Yu, ""Placing Racial Triangulation, Triangulating Place and Race: Chinese Grocery Stores in the Mississippi Delta during the Jim Crow Era,"" Annals of the American Association of Geographers, 112(1) 2022, pp. 97–122" Karin Lurvink, "Strapped for Cash: Non-cash Payments on Louisiana Cotton Plantations, 1865-1908," TIJDSCHRIFT VOOR SOCIALE EN ECONOMISCHE GESCHIEDENIS 11, 3 (2014) Sonny Albarado, "The violent and racist fight against laborers' basic rights in the South," Arkansas Advocate, 2023 Katrina Hazzard-Donald, Mojo Workin': The Old African-American Hoodoo System (University of Illinois Press, 2013).  Cierra Black, "Sinners Hoodoo Consultant Talks Working with Ryan Coogler & Protecting Black Spirituality On-Screen: 'Blues Is the Music of Hoodoo'" Teen Vogue 3 May 2025.  Marcelitte Failla, ""You Deserve, Baby!": Spiritual Co-creation, Black Witches, and Feminism," The Witch Studies Reader 75-89 (Duke University Press, 2025). https://www.jstor.org/stable/jj.25003747.9  Kinitra D. Brooks, "Haints, Hollers, and Hoodoo," Southern Cultures 29:4 (2023): 2-7. Zora Hurston, "Hoodoo in America," The Journal of American Folklore 44:174 (1931): 317-417. https://www.jstor.org/stable/535394  "The Rocky Road to Dublin" in Will Carleton, Will Carleton's "Dandy Pat Songster (1866). https://www.google.com/books/edition/Will_Carleton_s_Dandy_Pat_Songster/ULo-AQAAMAAJ?hl=en&gbpv=1&dq=%22Rocky%20Road%20to%20Dublin%22&pg=PA59&printsec=frontcover  The Citizen (1842), https://www.google.com/books/edition/The_Citizen/VYdPAQAAMAAJ?hl=en&gbpv=1&dq=%22Rocky%20Road%20to%20Dublin%22&pg=PA262&printsec=frontcover  https://www.google.com/books/edition/Diprose_s_Standard_Song_Book_and_Reciter/jzJYAAAAcAAJ?hl=en&gbpv=1&dq=Rocky%20Road%20to%20Dublin&pg=PA24&printsec=frontcover "The Rocky Road to Dublin," in The New Singer's Journal (1871) https://www.google.com/books/edition/Henry_De_Marsan_s_New_Comic_and_Sentimen/3Lk_AQAAMAAJ?hl=en&gbpv=1&dq=%22Rocky%20Road%20to%20Dublin%22&pg=PA175&printsec=frontcover  The rocky road to Dublin. Image. https://www.loc.gov/item/amss-as111860/  "Along the Rocky Road to Dublin" (1915) https://egrove.olemiss.edu/sharris_c/92/  D Taylor, "'Champagne Charlie is my name': The swell, the Irish and the cockney," in From Mummers to Madness (2021).  Michael Pierse, ""A Pole of Differentiation": Pasts and Futures in Irish Working-Class Writing," Working-Class Literature(s): Historical and International Perspectives (2020).  "The Schools' Collection" folklore collected by students in Ireland from 1937-1939 https://www.duchas.ie/en/cbes/stories?SearchText=blackthorn&SearchLanguage=ga&Page=1&PerPage=20 https://www.myirishjeweler.com/blog/irish-folklore-the-blackthorn-and-fairies-fighting-and-harry-potter/?srsltid=AfmBOoqlYcrE-xW106rf2XlffXUu-8oyNtkuISgfqsRmUOsNFEh0g9RU  RT: https://www.rottentomatoes.com/m/sinners_2025  Richard Brody, ""Sinners" is a Virtuosic Fusion of Historical Realism and Horror," April 17, 2025 The New Yorker https://www.newyorker.com/magazine/2025/04/28/sinners-movie-review  Wiki: https://en.wikipedia.org/wiki/Sinners_(2025_film) https://en.wikipedia.org/wiki/First-dollar_gross 

ReferencesGuerra. DJ. 2025. Unpublished LecturesFront. Immunol.,2024. 22 February Sec. Multiple Sclerosis and Neuroimmunology Volume 15 .Annals of Clinical & Laboratory Science.2022.vol. 52, no. 5 pp763-771.Mol Biosyst. 2014 Oct;10(10):2505-8. Frey/Henley. 1973. "Desperado" The Eagleshttps://music.youtube.com/playlist?list=OLAK5uy_k3UBMdBe0k-PWX6y1VCLJZVJogoUaKEco&si=9kkmSQG5xcdpbINRWelch, B 1973. "Emerald Eyes" Fleetwood Mac.Mystery to Me lp.https://music.youtube.com/watch?v=DnQM535xV-U&si=sRsNuXaEJ1A4VWPJ

Is there a better, safer, FREE alternative to Ozempic (and other GLP-1 drugs)? In this episode of Walk, Don't Run to the Doctor, Miles Hassell MD reacts to the growing buzz and shares a time-tested, evidence-based 3-step plan that outperforms popular weight loss drugs in the long run. As GLP-1 drugs like Ozempic, Wegovy, and Mounjaro surge in popularity, Dr. Hassell offers critical insight into their risks—like muscle loss, pancreatic complications, and long-term unknowns—while proposing a practical, natural alternative for lasting weight loss and better metabolic health. Key Takeaways: Why Big Pharma's track record with weight loss drugs demands caution The secret 3-step plan: Eat 6 servings of fruits & veggies, 3 minutes of daily exercise, reduce refined carbs Bonus tips: Bust cravings by eating protein with every meal, daily probiotics, and unlock the power of preemptive eating Why this plan costs nothing, has zero side effects, and starts showing results in just one week A timely message in light of the weight loss drug headlines—who should be in control of your health?  More references can be found at www.GreatMed.org Get your copy of Good Food Great Medicine. https://a.co/d/ajAzYzo Would you like Dr. Hassell to answer your question on the air? Contact us! Phone/text: 503-773-0770 e-mail: info@GreatMed.org Write us a letter. We love to hear from you. This podcast is sponsored by our generous listeners. Send questions, comments, and support to: 4804 NW Bethany Blvd., Suite I-2, #273 Portland OR 97229 References: Chen, X., et al. (2025). Association of dietary fiber intake with all-cause and cardiovascular mortality in diabetes and prediabetes. Diabetology & metabolic syndrome, 17(1), 231. https://pubmed.ncbi.nlm.nih.gov/40533827/   Look, M., et al. (2025). Body composition changes during weight reduction with tirzepatide in the SURMOUNT-1 study of adults with obesity or overweight. Diabetes, obesity & metabolism, 27(5), 2720–2729. https://pubmed.ncbi.nlm.nih.gov/39996356/   Wilding, J., et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. The New England journal of medicine, 384(11), 989–1002. https://pubmed.ncbi.nlm.nih.gov/33567185/   Tinsley, G. M., & Heymsfield, S. B. (2024). Fundamental Body Composition Principles Provide Context for Fat-Free and Skeletal Muscle Loss With GLP-1 RA Treatments. Journal of the Endocrine Society, 8(11),https://pubmed.ncbi.nlm.nih.gov/39372917/    Neeland, I. J., et al. (2024). Changes in lean body mass with glucagon-like peptide-1-based therapies and mitigation strategies. Diabetes, obesity & metabolism, 26 Suppl 4, 16–27. https://pubmed.ncbi.nlm.nih.gov/38937282/   Sato, M., et al. (2023). Relationships among Postprandial Plasma Active GLP-1 and GIP Excursions, Skeletal Muscle Mass, and Body Fat Mass in Patients with Type 2 Diabetes Treated with Either Miglitol, Sitagliptin, or Their Combination: A Secondary Analysis of the MASTER Study. Journal of clinical medicine, 12(9), 3104. https://pubmed.ncbi.nlm.nih.gov/37176545/   Monami, M., et al. (2017). Safety issues with glucagon-like peptide-1 receptor agonists (pancreatitis, pancreatic cancer and cholelithiasis): Data from randomized controlled trials. Diabetes, obesity & metabolism, 19(9), 1233–1241. https://pubmed.ncbi.nlm.nih.gov/28244632/   Anderson, S. L., & Trujillo, J. M. (2010). Association of pancreatitis with glucagon-like peptide-1 agonist use. The Annals of pharmacotherapy, 44(5), 904–909. https://pubmed.ncbi.nlm.nih.gov/20371755/   Kapoor, I., Sarvepalli, S. M., D'Alessio, D., Grewal, D. S., & Hadziahmetovic, M. (2023). GLP-1 receptor agonists and diabetic retinopathy: A meta-analysis of randomized clinical trials. Survey of ophthalmology, 68(6), 1071–1083. https://pubmed.ncbi.nlm.nih.gov/37454782/   Bikou, A., et al. (2024). A systematic review of the effect of semaglutide on lean mass: insights from clinical trials. Expert opinion on pharmacotherapy, 25(5), 611–619. https://pubmed.ncbi.nlm.nih.gov/38629387/   Jalleh, R. J., et al. (2024). Clinical Consequences of Delayed Gastric Emptying With GLP-1 Receptor Agonists and Tirzepatide. The Journal of clinical endocrinology and metabolism, 110(1), 1–15. https://pubmed.ncbi.nlm.nih.gov/39418085/   Berg, S. AMA. (2023). Questions patients may have about weight-loss drugs. https://www.ama-assn.org/delivering-care/public-health/questions-patients-may-have-about-weight-loss-drugs   Friedman, J. (2025). America's up-and-down history with weight-loss drugs. https://www.history.com/articles/weight-loss-drugs-america    

In this fan favorite episode of the podcast, Dr. Bray answers a listener's question on loneliness.  Tune in to learn about the neuroscience and psychology of loneliness, what happens in the brain, and specific action steps you can take to combat loneliness.  In a world where loneliness is increasing exponentially, it is important to understand this issue and notice the signs and warning markers of isolation.  If you want to learn more, see below for specific research into the topics Dr. Bray discussed on this episode. “Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies” by Nicole K Valtorta et al. Heart “Loneliness matters: a theoretical and empirical review of consequences and mechanisms. Annals of Behavioral Medicine” by Louise C. Hawkley et al. Annals of Behavioral Medicine “The growing problem of loneliness” by Cacioppo & Cacioppo. The Lancet “Brain structure links loneliness to social perception” by Ryota Kanai et al. Current Biology “The association between social relationships and depression: a systematic review” by Ziggi Ivan Santini et al. Journal of Affective Disorders “The neuroendocrinology of social isolation” by John Cacioppo et al. Annual Review of Psychology “Social media use and perceived social isolation among young adults in the US” by Brian A. Primack et al. American Journal of Preventative Medicine “A meta-analysis of interventions to reduce loneliness” by Christopher M. Masi et al. Personality and Social Psychology Review “Mindfulness training reduces loneliness and increases social contact in a randomized controlled trial” by Emily K. Lindsay et al. PNAS QUOTES BY DR. BRAY “Loneliness can creep in no matter how connected we may appear or seem to be.” “The key to perception is understanding.” “Social media never replaces personal connection.”  

In S6 E5 I am delighted to welcome Dr Colin West MD PhD to the podcast. Dr West is a practising physician, educator, biostatistician and he is globally renowned for his research in professional and organisational wellbeing in healthcare. He has been deeply embedded in research work in this area with colleagues at Mayo Clinic for over two decades to advance and inform healthcare organisational and clinician wellbeing leadership, strategy and evidence-informed system and work unit interventions to promote physician wellbeing and reduce distress. Dr West is the inaugural program director for physician wellbeing at Mayo Clinic. He is the recipient of multiple awards for his research and education work and collaborates extensively with scientists and groups within and outside Mayo Clinic. External collaborations include members of leadership in the American Medical Association. His work with colleagues including Dr Tait Shanafelt has  been published in multiple top-tier journals, including the Lancet, the Journal of the American Medical Association, Annals of Internal Medicine, and JAMA Internal Medicine.   In this conversation we discuss the evolution of his work over the past two decades. We learn how the combination of unique skills, intellectual curiosity and a deep investment and sense of purpose led to a critical coalition of colleagues who have helped to advance and build evidence-informed road maps and organisational blueprints  to promote physician wellbeing and professional satisfaction and reduce burnout and distress. I was particularly keen to explore some of the key intervention studies including the COMPASS trail ( Colleagues Meeting to Promote and Sustain Satisfaction) and the research about leadership capability and coaching/development. This episode is full of both the science and practical wisdom Dr West brings as a clinical expert in this field and yet still scratches the surface of his work.  A lot of his efforts today centre on attention to the MVPs ( meaning values and purpose )of professional wellbeing for his colleagues and the work they do in turn for their patients. He finishes with a powerful call to action at this juncture and critical inflection point for healthcare and clinicians globally. This is fundamentally important work and I am grateful to Colin and colleagues for continuing to advance our knowledge and applied practice. Links/References/ResourcesDr West's Wellbeing Wednesday Thread https://www.linkedin.com/posts/colin-west-57821b82_colin-west-colinwestmdphd-on-x-activity-7252370843236749312-1WMg/https://www.mayo.edu/research/faculty/west-colin-p-m-d-ph-d/bio-00027800https://edhub.ama-assn.org/steps-forward/pages/professional-well-beingThe COMPASS Trial https://pubmed.ncbi.nlm.nih.gov/34366134/Register for the Australasian Doctors' Health conference to continue to the conversation in 2025:https://adhc.org.au/The Mind Full Medic Podcast is proudly sponsored by the MBA NSW-ACT Find out more about their service or donate today at www.mbansw.org.auDisclaimer: The content in this podcast is not intended to constitute or be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your doctor or other qualified health care professional. Moreover views expressed here are our own and do not necessarily reflect those of our employers or other official organisations.

Honorary third host of the podcast Kaylee is back this week to join us in discussing the R.J. Hackett, a vessel that changed the way bulk cargo was transported on the Great Lakes and laid the groundwork for the designs we still see today. gazafunds.comSources: Baker, Newton D. “Transportation on the Great Lakes.” The Annals of the American Academy of Political and Social Science, vol. 171, Jan 1934, pp. 204 - 210. Bowlus, Bruce. “Bold Experiments: The Evolution of the Great Lakes Ore Carrier.” Michigan Historical Review, vol. 22, no. 1, Spring 1996, pp. 1 - 17. “Steamer Hackett Burns.” The Sturgeon Bay Advocate, vol. 44, no. 34, 18 Nov 1905. Support the show

Hello!New episode for your archaeogastronomical delights , is out now!Today I have author, chef and food historian Jay Reifel in this episode as my guest, and we muse about all things "Baghdadical"!10th century Baghdad the capital of the Islamic world in a sense it was a sensuous place.And it produced perhaps a cookbook, more than mere recipes something extremely modern in some senses, and something that didn't exist in the West (if we want to put labels on things) for another 400 years or so!This cookbook, "The Annals of the Caliph's Kitchen" contained a treasure of information and it was more than 500 pages long!What's Jay's favourite recipes, what did the Abbasids loved to cook and eat and what were the ingredients that we might not know today?Anyway I hope you'll enjoy today's musings!Love,Thom & The Delicious LegacySupport this show http://supporter.acast.com/the-delicious-legacy. Hosted on Acast. See acast.com/privacy for more information.

Still struggling with IBS symptoms, even after trying everything?   It might not be “just IBS.”   In the first episode of The Gut Show, Season 8, Dr. Mark Pimentel breaks down the connection between SIBO, IMO, ISO, and IBS, and what patients need to know about testing, treatment, and what's actually causing your symptoms.   We talked about breath tests, stool tests, probiotics, antibiotics (like Rifaximin + Neomycin), the meds that cause SIBO, and more.   Covered in this episode: Introducing Dr. Pimentel, MD [2:18] What is SIBO, ISO and IMO? [3:18] Should everyone with IBS do breath testing? [7:14] New guidelines that have come out [9:50] How should a patient navigate testing? [11:11] What about stool testing? [13:16] Negative test + symptoms or positive test without symptoms [16:50] What does normal mean? [18:44] Who does all 3 [20:39] Glucose vs Lactulose for the test [21:05] What causes these overgrowths? [21:52] The medication that WILL make you have SIBO [23:53] MAST cells, IBD, endometriosis [24:34] Treatment [32:07] Rifaximin [34:19] Any Statin or seaweed based treatment updates? [37:51] Neomycin [39:25] Elemental diet [41:23] What Dr. Pimentel wants for his patients [45:17] Probiotics [46:40] The role of metabolic disorders [48:22] Rapid fire questions [50:59]   Mentioned in this episode:  MASTER Method Membership Take the quiz: What's your poop personality?      Sponsors of The Gut Show:  FODZYME is the world's first enzyme supplement specialized to target FODMAPs. When sprinkled on or mixed with high-FODMAP meals, FODZYME's novel patent-pending enzyme blend breaks down fructan, GOS and lactose before they can trigger bloating, gas and other digestive issues. With FODZYME, enjoy garlic, onion, wheat, Brussels sprouts, beans, dairy and more — worry free! Discover the power of FODZYME's digestive enzyme blend and eat the foods you love and miss. Visit fodzyme.com and save 20% off your first order with code THEGUTSHOW. One use per customer. Gemelli Biotech offers trusted, science-backed at-home tests for conditions like SIBO, IMO, ISO, and post-infectious IBS.  Their Trio-Smart breath test measures all three key gases: hydrogen, methane, and hydrogen sulfide to detect different forms of microbial overgrowth. And for those with IBS symptoms, IBS-Smart is a simple blood test that can confirm post-infectious IBS with clinical accuracy. You simply order the test, complete it at home, send it back, and get clinically backed results in about a week that you can take to your provider!  Find out which tests are right for you at getgutanswers.com and use code ERINJUDGE25 to save $25 on your order!   About our speaker: Mark Pimentel, MD, FRCP(C), is a Professor of Medicine at Cedars-Sinai and Professor of Medicine and of Gastroenterology through Geffen School of Medicine. Dr. Pimentel is also the Executive Director of the Medically Associated Science and Technology (MAST) program at Cedars-Sinai, an enterprise of physicians and researchers dedicated to the study of the gut microbiome in order to develop effective diagnostic tools and therapies to improve patient care. As a physician and researcher, Dr. Pimentel has served as a principal investigator or co-investigator for numerous basic science, translational and clinical investigations of irritable bowel syndrome (IBS) and the relationship between gut flora composition and human disease. This research led to the first ever blood tests for IBS, ibs-smart™, the only licensed and patented serologic diagnostic for irritable bowel syndrome. The test measures the levels of two validated IBS biomarkers, anti-CdtB and anti-vinculin. A pioneering expert in IBS, Dr. Pimentel's work has been published in the New England Journal of Medicine, Annals of Internal Medicine, American Journal of Physiology, American Journal of Medicine, American Journal of Gastroenterology and Digestive Diseases and Sciences, among others. Dr. Pimentel has presented at national and international medical conferences and advisory boards. He is a diplomate of the American Board of Internal Medicine (Gastroenterology,) a fellow of the Royal College of Physicians and Surgeons of Canada and a member of the American Gastroenterological Association, the American College of Gastroenterology, and the American Neurogastroenterology and Motility Society. Dr. Pimentel completed 3 years of an undergraduate degree in honors microbiology and biochemistry at the University of Manitoba, Canada. This was followed by his medical degree, and his BSc (Med) from the University of Manitoba Health Sciences Center in Winnipeg, Manitoba, Canada, where he also completed a residency in internal medicine. His medical training includes a fellowship in gastroenterology at the UCLA Affiliated Training Program.   Connect with Erin Judge, RD:  IG: https://www.instagram.com/erinjudge.rd TikTok: https://www.tiktok.com/@erinjudge.rd   Work with Gutivate:  https://gutivate.com/services   

Men don't have enough important dates to forget about? Gen Z wants WHAT at the office? Wait... Bob Vila is CUBAN?!?! Come learn other stupid things with us!PLUS: Celebrity birthdays!The Treehouse is a daily DFW based comedy podcast and radio show. Leave your worries outside and join Dan O'Malley, Trey Trenholm, Raj Sharma, and their guests for laughs about current events, stupid news, and the comedy that is their lives. If it's stupid, it's in here.The Treehouse WebsiteGet 60% off the Magic Mind offer with our link and code:  https://magicmind.com/ttsmf & TREEHOUSE60 #magicmind #mentalwealth #mentalperformanceGet a FREE roof inspection from the best company in DFW:Cook DFW Roofing & Restoration Defender OutdoorsUse code TREEHOUSE to unlock special discounts at Defender Outdoors!CLICK HERE TO DONATE:The RMS Treehouse Listeners FoundationLINKS:Airline Passenger's Violent Meltdown, Fight in Aisle Caught on VideoHow Remote Work Is Changing Gen Z's Sex Lives - EduBirdie.comWhy couples are celebrating wild 'arbitrary-versaries'Tequila-marinated turkey causes oven mishap on Madison's west side | News | channel3000.com

Episode 194: Acute low back pain.  Future Dr. Ibrahim presents a clinical case to explain the essential points in the evaluation of back pain.  Future Dr. Redden adds information about differentiating between a back strain and more serious diseases such as cancer, and Dr. Arreaza shares information about returning to work after back strain.Written by Michael Ibrahim, MSIV. Editing and comments by Jordan Redden, MSIV, and Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Dr. Arreaza:Welcome back, everyone. Today's topic is one that every primary care provider, emergency doctor, and even specialist sees routinely: low back pain. It's so common that studies estimate up to 80% of adults will experience it at some point in their lives. But despite how frequent it is, the challenge is to identify which cases are benign and which demand urgent attention.Jordan:Exactly. Low back pain is usually self-limiting and mechanical in nature, but we always need to keep an eye out for the rare but serious causes: things like infection, malignancy, or neurological compromise. That's why a good history and physical exam are our best tools right out of the gate.Michael:And to ground this in a real example, let me introduce a patient we saw recently. John is a 45-year-old warehouse worker who came in with two weeks of lower back pain that started after lifting a 50-lb box. He describes it as a dull, aching pain that radiates from his lower back down the posterior left thigh into the calf. He says it gets worse with bending or coughing, but he feels better when lying flat. He also mentioned some numbness in his left foot, but he denies any bowel or bladder issues. His vitals are completely normal. On exam, he had lumbar paraspinal tenderness, a positive straight leg-raise at 40 degrees on the left and decreased sensation in the L5 dermatome, though reflexes were still intact.Dr. Arreaza:That's a great case. Let's take a minute and talk about the straight leg raise test. This is a bedside tool we use to assess for lumbar nerve root irritation often caused by a herniated disc. ***Here's how it works: the patient lies supine, and you slowly raise their straight leg. If pain radiates below the knee between 30° and 70°, that suggests radiculopathy, especially involving the L5 or S1 nerve roots. Pain at higher angles is more likely due to hamstring tightness or mechanical strain.Michael:Right. So, stepping back: what do we mean by "low back pain"? Broadly, it's any pain localized to the lumbar spine, but it's often classified by type or cause:Mechanical (like muscle strain or degenerative disc disease), Radicular (nerve root involvement), Referred pain (like from pelvic or abdominal organs), Inflammatory (AS), and Systemic or serious causes like infection or malignancy. Jordan:In John's case, we're thinking radicular pain, most likely from a herniated disc compressing the L5 nerve root. That's supported by the dermatomal numbness, the leg pain, and that positive straight leg test.Dr. Arreaza:Good reasoning. Now, anytime we see back pain, our brains should run a checklist for red flags. These help us pick up more serious causes that require urgent attention. Let's run through the red flags.Michael:Sure. For fracture, we think about major trauma or even minor trauma in the elderly, especially those with osteoporosis or on chronic steroids. Also, anyone over 70 years old.Jordan:Then we have infections, which could include things like discitis, vertebral osteomyelitis, or epidural abscess. Red flags include fever, IV drug use, recent surgery, or immunosuppression.Michael:Malignancy is another critical one, especially if there's a history of breast, prostate, lung, kidney, or thyroid cancer. Clues include unexplained weight loss, night pain, or constant pain not relieved by rest.Jordan:And don't forget about inflammatory back pain, like ankylosing spondylitis, which is often seen in younger patients with morning stiffness that lasts more than 30 minutes and improves with activity.Dr. Arreaza:And of course, we always rule out cauda equina syndrome: a surgical emergency. That's urinary retention or incontinence, saddle anesthesia, bilateral leg weakness, or fecal incontinence. Missing this diagnosis can be catastrophic.Michael:Thankfully, in John's case, we don't see any red flags. His presentation is classic for uncomplicated lumbar radiculopathy. But we must stay vigilant, because sometimes patients don't offer up key symptoms unless we ask directly.Jordan:And that's where associated symptoms help guide us. For example:Radicular symptoms like numbness or weakness follow dermatomal patterns. Constitutional symptoms like fever or weight loss raise red flags. Bladder/bowel changes or saddle anesthesia raise alarms for cauda equina. Pain that wakes patients up at night might point to malignancy. Dr. Arreaza:So when do we order labs or imaging?Michael:Not right away. For most patients with acute low back pain, imaging is not needed unless they have red flags. If infection is suspected, we'd get CBC, ESR, and CRP. For cancer, maybe PSA or serum protein electrophoresis. And if inflammatory back disease is suspected, HLA-B27 can be helpful.Jordan:Yes, imaging should be delayed for at least six weeks unless red flags or significant neurologic deficits are present. When we do image, MRI is our go-to especially for suspected radiculopathy or cauda equina. X-rays can help if we're thinking about fractures, but they won't show soft tissue or nerve root issues.Michael:In the example from our case, since the patient doesn't have red flags, we'd go with conservative management: start NSAIDs and recommend activity modification. As this is the acute setting, physical therapy would not be recommended.Jordan:For the acute phase, research shows no serious difference between those with PT and those without in the long term. However, physical therapy is really the cornerstone of management for chronic back pain. It's not just movement: it's education, body mechanics, and teaching patients how to move safely. And PT can actually reduce opioid use, imaging, and injections down the line for patient struggling with long term back pain.Dr. Arreaza:Yes, and PT is not one-size-fits-all. PT might include McKenzie exercises, manual therapy, postural retraining, or even neuromuscular re-education. The goal is always to build core stability, promote healthy movement patterns, and reduce fear of motion.Jordan:Let's take a minute to talk about the McKenzie Method, a physical therapy approach used to treat lumbar disc herniation by identifying a specific movement, (often spinal extension) that reduces or centralizes pain. A common exercise is the prone press-up, (cobra pose for yoga fans) where the patient lies face down and pushes the upper body upward while keeping the hips on the floor to relieve pressure on the disc. These exercises should be done carefully, ideally under professional guidance, and discontinued if symptoms worsen.Michael:For our case patient, our working diagnosis is mechanical low back pain with L5 radiculopathy. No imaging needed now, no red flags. We'll treat conservatively and educate him about proper lifting, staying active, and recovery expectations.Jordan:We also emphasized to him that bed rest isn't helpful. In fact, bed rest can make things worse. Keeping active while avoiding heavy lifting for now is key.Dr. Arreaza:Return-to-work recommendations should be individualized. For example, an office worker, positioning while working, or work hours may be able to return to work promptly. However, those with physically demanding jobs may need light duty or be off work.Ice: no evidence of benefit. Heat: may reduce pain and disability in pain of less than 3 months, although the benefit was small and short.And we should always teach safe lifting techniques: bend at the knees, keep the load close, avoid twisting. It's basic knowledge, but it is very effective in preventing recurrence.Jordan:Now, if a patient fails to improve after 6 weeks of conservative therapy, or if they develop new neurologic deficits, that's when we think about referral to spine specialists or surgical consultation.Michael:And as previously mentioned: in cases where back pain becomes chronic (lasting more than 12 weeks) a multidisciplinary approach works best. That can include:Physical therapy, Cognitive behavioral therapy (CBT) And sometimes pain management interventions. Jordan:We can't forget the psychological toll either. Chronic back pain is associated with depression, anxiety, and opioid dependence. Increased risk factors include obesity, smoking, sedentary lifestyle, and previous back injuries.Dr. Arreaza:Well said. So, let's summarize. Michael?Michael:Sure! Low back pain is common, and most cases are benign. But we have to know the red flags that point to serious pathology. A focused history and physical exam are more powerful than many people realize. And the first step in treatment is almost always conservative, with a strong emphasis on maintaining physical activity.Jordan:And don't underestimate the value of patient education. Helping patients understand their pain, set realistic expectations, and stay active is often just as important as the medications or therapies we offer.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Chou, R., Qaseem, A., Snow, V., Casey, D., Cross, J. T., Shekelle, P., & Owens, D. K. (2007). Diagnosis and treatment of low back pain: A joint clinical practice guideline from the American College of Physicians and the American Pain Society. Annals of Internal Medicine, 147(7), 478–491. https://doi.org/10.7326/0003-4819-147-7-200710020-00006Deyo, R. A., Mirza, S. K., Turner, J. A., & Martin, B. I. (2009). Overtreating chronic back pain: Time to back off? Journal of the American Board of Family Medicine, 22(1), 62–68. https://doi.org/10.3122/jabfm.2009.01.080102National Institute for Health and Care Excellence. (2020). Low back pain and sciatica in over 16s: Assessment and management (NICE Guideline No. NG59). https://www.nice.org.uk/guidance/ng59Qaseem, A., Wilt, T. J., McLean, R. M., & Forciea, M. A. (2017). Noninvasive treatments for acute, subacute, and chronic low back pain: A clinical practice guideline from the American College of Physicians. Annals of Internal Medicine, 166(7), 514–530. https://doi.org/10.7326/M16-2367UpToDate. (n.d.). Evaluation and treatment of low back pain in adults. Wolters Kluwer. https://www.uptodate.com (Access requires subscription)Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/. 

In this episode of The Breast Cancer Recovery Coach, we'll dismantle three of the most common—and misleading—nutrition myths that many women encounter after a breast cancer diagnosis. Whether you're in active treatment or navigating life post-cancer, this conversation offers clarity, compassion, and practical advice rooted in science, not fear.   You'll learn: Why not all carbohydrates are harmful and how whole-food carbs can actually support healing The truth about plant vs. animal foods and how to identify clean, high-quality animal proteins How “organic” and “plant-based” labels can mislead your food choices—and what to look for instead If you've ever felt confused or overwhelmed by nutrition advice, this episode will help you reconnect with your body, make informed choices, and feel confident in the way you nourish yourself. Topics Covered: The real difference between simple and complex carbohydrates How to eat carbs while maintaining stable blood sugar Nutrient density and bioavailability of animal vs. plant foods What qualifies as a clean animal food and why it matters The “health halo effect” of organic and plant-based labels Tips for tuning out food fear and tuning into what works for your body   Resources & References: Work with Laura Study: Glycemic load and cancer risk – Nutrition Journal Study: Dietary fiber intake and breast cancer – Annals of Oncology Study: Macronutrient combinations and glycemic response – Diabetes Care Study: Organic labeling and perception – Food Quality and Preference Study: Health halo of plant-based labels – Appetite (2018) Study: Plant-based health halo and risk perception – Appetite (2019)   Loved this episode? Share it with a friend or leave a review on Apple Podcasts to help more survivors find compassionate, clear guidance on living well after breast cancer.   Connect with Laura Lummer:

This new series will be a collaboration between BTK and Annals of Surgery, where we will be discussing hot topics in surgery research. No, we won't be getting into the nitty gritty of methods of individual papers but rather will focus on high-level discussions of contemporary topics that are moving our field forward. Hosts: Cody Mullens, MD is a general surgery resident at the University of Michigan, current Behind the Knife Surgery Education Fellow. (@Cody_Mullens) Justin B. Dimick, MD MPH is the Fredrick A Coller Distinguished Professor and Chair of Surgery at the University of Michigan. He also serves as the Editor in Chief at Annals of Surgery. (@jdimick1) Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://app.behindtheknife.org/listen

This is the last episode of season FOUR! Whenever we wrap up a season, we like to look back and chat about each episode, provide some important takeaways, and share information about actionable steps you can take this summer to keep growing your knowledge base. Resources mentioned in this episode: All episodes of the Together in Literacy podcast Towards a dynamic, comprehensive conceptualization of dyslexia. Annals of dyslexia Super Dville 2.14 Using Evaluations to Better Understand Our Learners with Katy Vassar 2.4 How to Effectively Work with Older Students with Dyslexia 2.5 Word Attack Strategies for Older Students with Dyslexia Building Readers for Life Summer Conference Empowered Beyond the Program Membership Teaching Beyond the Diagnosis: Empowering Students with Dyslexia by Casey Harrison We officially have merch! Show your love for the Together in Literacy podcast! If you like this episode, please take a few minutes to rate, review, and subscribe. Your support and encouragement are so appreciated! Have a question you'd like us to cover in a future episode of Together in Literacy? Email us at support@togetherinliteracy.com! If you'd like more from Together in Literacy, you can check out our website, Together in Literacy, or follow us on Facebook and Instagram. For more from Emily, check out The Literacy Nest. For more from Casey, check out The Dyslexia Classroom. We're looking for topic and guest suggestions for season 4 of the Together in Literacy Podcast! Let us know what you want to hear this season! Thank you for listening and joining us in this exciting and educational journey into dyslexia as we come together in literacy!

In this episode of The Teamcast, Dr. Angus Fletcher joins Preston Cline to discuss the crucial role of "productive discomfort" and honesty in personal and professional growth. They explore how embracing emotional challenges, rather than shielding individuals from them, is vital for true learning and resilience. Angus describes his concept of "story thinking," emphasizing the brain's natural inclination to process experiences through narrative and emotion. The conversation touches on the shortcomings of modern education in fostering emotional robustness and concludes with practical advice for leaders on cultivating independent thinking by recognizing and congratulating actions that differ from their own.Dr. Angus Fletcher is a professor and practitioner of Story Science at Project Narrative at The Ohio State University. He holds degrees in neuroscience and literature. His research, which employs a mix of laboratory experiments, literary history, and rhetorical theory, explores how literature, art, and stories can cultivate emotional resilience, creativity, and common sense. He is the author of Wonderworks (2021), Storythinking (2023), and Primal Intelligence (2025), among other books. His work explores why children are more creative than computer AI and aims to understand how narrative can be leveraged to enhance innovation, resilience, and joy. His academic publications can be found in journals like Narrative, Annals of the New York Academy of Sciences, and Harvard Business Review.Check out Angus's work here: https://www.angusfletcher.co/

Sometime in the 800s, an anonymous monk in the abbey of Fulda–now in modern Germany–copied out a Latin history in one of the great inventions of the age, the handwriting known as Carolingian miniscule, which is more or less they system that we use today to print the English alphabet. Thanks to that monk, today we have the first part of the Annals of P. Cornelius Tacitus, arguably the greatest surviving history of imperial Rome. But who was Tacitus? Why is he important? How could such an opinionated historian proclaim that he was writing without “anger and partiality”? Was he a champion of Roman liberty, or simply a grumpy aristocrat? With me to discuss Tacitus is Dr. Eric Adler, Professor and Chair of Classics at the University of Maryland. His scholarly interests include Roman historiography, Latin prose, the history of classical scholarship, and the history of the humanities. This is his second time on the podcast. His last appearance was in Episode 195, which dropped on January 20, 2021, in which we discussed his then third book, The Battle for the Classics: How a Nineteenth-Century Debate Can Save the Humanities Today.   For Further Investigation Eric Adler recommends "some scholarship" on Tacitus's Agricola: Clarke, Katherine. 2001. “An Island Nation: Re-Reading Tacitus' Agricola.” Journal of Roman Studies 91: 94-112. Liebeschuetz, W. 1966. “The Theme of Liberty in the Agricola of Tacitus.” Classical Quarterly n.s. 16.1: 126-139. Momigliano, Arnaldo. 2012 (1990). “Tacitus and the Tacitean Tradition.”In Tacitus, edited by Rhiannon Ash. 411-433. Oxford: Oxford University Press. Sailor, Dylan. 2004. “Becoming Tacitus: Significance and Inconsequentiality in the Prologue of Agricola.” Classical Antiquity 23.1: 139-177. Syme, Ronald. 1958. Tacitus, vols. 1-2. Oxford: Clarendon Press.

In our recent episode on global burn surgery with Dr. Barclay Stewart and Dr. Manish Yadav, we discussed several cases at Kirtipur Hospital in Nepal to illustrate the global burden of burns and similarities and differences in treating burns at Harborview Medical Center, a level 1 trauma and ABA verified burn center in Seattle, WA and Kirtipur Hospital (Nepal Cleft and Burn Center) in Kathmandu, Nepal. In this episode Dr. Stewart and Dr. Yadav return for an interview by UW Surgery Resident, Paul Herman, sharing insights on how to get involved in global surgery with an emphasis on sustainable participation. Hosts:  Manish Yadav, Kirtipur Hospital, Nepal Barclay Stewart, UW/Harborview Medical Center Paul Herman, UW/Harborview General Surgery Resident, @paul_herm  Tam Pham, UW/Harborview Medical Center (Editor) Learning Objectives 1.     Approaches to global surgery  a.     Describe historical perspectives on global health and global surgery reviewing biases global surgery inherits from global health due to the history of colonialism, neo-colonialism and systemic inequalities b.     Review a recently published framework and evaluation metrics for sustainable global surgery partnerships (GSPs) as described by Binda et al., in Annals of Surgery in March 2024. c.      Provide examples of this framework from a successful global surgery partnership d.     Define vertical, horizontal and diagonal global surgery approaches e.     Share tips for initial engagement for individuals interested in getting involved in global surgery References 1.     Gosselin, R., Charles, A., Joshipura, M., Mkandawire, N., Mock, C. N. , et. al. 2015. “Surgery and Trauma Care”. In: Disease Control Priorities (third edition): Volume 1, Essential Surgery, edited by H. Debas, P. Donkor, A. Gawande, D. T. Jamison, M. Kruk, C. N. Mock. Washington, DC: World Bank. 2.     Qin R, Alayande B, Okolo I, Khanyola J, Jumbam DT, Koea J, Boatin AA, Lugobe HM, Bump J. Colonisation and its aftermath: reimagining global surgery. BMJ Glob Health. 2024 Jan 4;9(1):e014173. doi: 10.1136/bmjgh-2023-014173. PMID: 38176746; PMCID: PMC10773343. https://pubmed.ncbi.nlm.nih.gov/38176746/ 3.     Binda CJ, Adams J, Livergant R, Lam S, Panchendrabose K, Joharifard S, Haji F, Joos E. Defining a Framework and Evaluation Metrics for Sustainable Global Surgical Partnerships: A Modified Delphi Study. Ann Surg. 2024 Mar 1;279(3):549-553. doi: 10.1097/SLA.0000000000006058. Epub 2023 Aug 4. PMID: 37539584; PMCID: PMC10829902.  https://pubmed.ncbi.nlm.nih.gov/37539584/ 4.     Jedrzejko N, Margolick J, Nguyen JH, Ding M, Kisa P, Ball-Banting E, Hameed M, Joos E. A systematic review of global surgery partnerships and a proposed framework for sustainability. Can J Surg. 2021 Apr 28;64(3):E280-E288. doi: 10.1503/cjs.010719. PMID: 33908733; PMCID: PMC8327986. https://pubmed.ncbi.nlm.nih.gov/33908733/ 5.     Frenk J, Gómez-Dantés O, Knaul FM: The health systems agenda: prospects for the diagonal approach. The handbook of global health policy. 2014 Apr 24; pp. 425–439 6.     Davé DR, Nagarjan N, Canner JK, Kushner AL, Stewart BT; SOSAS4 Research Group. Rethinking burns for low & middle-income countries: Differing patterns of burn epidemiology, care seeking behavior, and outcomes across four countries. Burns. 2018 Aug;44(5):1228-1234. doi: 10.1016/j.burns.2018.01.015. Epub 2018 Feb 21. PMID: 29475744. https://pubmed.ncbi.nlm.nih.gov/29475744/ 7.     Strain, S., Adjei, E., Edelman, D. et al. The current landscape of global international surgical rotations for general surgery residents in the United States: a survey by the Association for Program Directors in Surgery's (APDS) global surgery taskforce. Global Surg Educ 3, 77 (2024). https://doi.org/10.1007/s44186-024-00273-2 8.     Francalancia S, Mehta K, Shrestha R, Phuyal D, Bikash D, Yadav M, Nakarmi K, Rai S, Sharar S, Stewart BT, Fudem G. Consumer focus group testing with stakeholders to generate an enteral resuscitation training flipbook for primary health center and first-level hospital providers in Nepal. Burns. 2024 Jun;50(5):1160-1173. doi: 10.1016/j.burns.2024.02.008. Epub 2024 Feb 15. PMID: 38472005; PMCID: PMC11116054. https://pubmed.ncbi.nlm.nih.gov/38472005/ 9.     Shrestha R, Mehta K, Mesic A, Dahanayake D, Yadav M, Rai S, Nakarmi K, Bista P, Pham T, Stewart BT. Barriers and facilitators to implementing enteral resuscitation for major burn injuries: Reflections from Nepalese care providers. Burns. 2024 Oct 28;51(1):107302. doi: 10.1016/j.burns.2024.107302. Epub ahead of print. PMID: 39577105. https://pubmed.ncbi.nlm.nih.gov/39577105/ Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://app.behindtheknife.org/listen