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U of I Cereals Pathologist Concerned about Idaho stripe rust outlook
U of I Cereals Pathologist Concerned about Idaho stripe rust outlook
In this episode: What are the red flags when examining lesions in fingers or toes? Why is it important to examine fingers and toes at the same time? What ethnicities and age groups of patients are at higher risk of skin lesions? When looking at longitudinal melanonychia, what signs indicate patient needs to be referred to a Dermatologist? “Furrows are friendly, ridges are risky” – understand this mnemonic used commonly by Dermatologists Taking a clinical photograph of the lesion is always helpful in monitoring, even for patients, as most of these lesions grow slowly Host: Dr David Lim, GP and Medical Educator Expert: Dr Philip Tong, Dermatologist Total time: 24 mins Register for our fortnightly FREE WEBCASTS Every second Tuesday | 7:00pm-9:00pm AEDT Click here to register for the next oneSee omnystudio.com/listener for privacy information.
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Viewing several skin cases day after day can make recognizing different types of skin lesions daunting... However, evaluating skin integrity, alopecia, skin thickness, etc. can help guide the differential list and fine tune the diagnostic approach.Learn more on this week's episode of The Derm Vet podcast!TIMESTAMPS00:00 Intro00:25 What and where when it comes to lesions01:54 Color change06:09 Alopecia07:41 Thickening of the skin09:33 Scaling10:56 Skin Integrity13:07 Summary
Full article: Nonmass Lesions on Breast Ultrasound: Interreader Agreement and Associations With Malignancy Kamyar Ghabili, MD, discusses the AJR article by Cho et al. exploring issues related to nonmass lesions on breast ultrasound.
Dr. Reni Butler speaks with Dr. Ji Soo Choi about her groundbreaking study on non-mass lesions in screening breast ultrasound. Explore key imaging features, their predictive value for malignancy, and how the upcoming BI-RADS lexicon update could transform breast cancer diagnosis. Assessment of Nonmass Lesions Detected with ScreeningBreast US Based on Mammographic Findings. Ha and Choi et al. Radiology 2024; 313(2):e240043
In this episode of SurgOnc Today®, Steve Kwon, MD, and Mike Mavros, MD, are joined by Joo Ha Hwang, MD, and Yanghee Woo, MD, for a discussion of managing patients at high-risk of gastric cancer development at the population-level and at the patient-level. The panel will also discuss nonoperative and operative strategies in managing precancerous gastric lesions and early gastric cancers.
En este episodio, resumimos varios artículos científicos sobre espasticidad, en cuanto a conceptualización, neurofisiología, evaluación y tratamiento. Es una forma de actualización anual sobre esta temática tan estudiada en neurociencia. Hablamos sobre nuevos estudios de neuroimagen sobre la espasticidad, consensos sobre evaluación y desarrollos emergentes de tratamientos médicos. Referencias del episodio: 1. Cho, M. J., Yeo, S. S., Lee, S. J., & Jang, S. H. (2023). Correlation between spasticity and corticospinal/corticoreticular tract status in stroke patients after early stage. Medicine, 102(17), e33604. https://doi.org/10.1097/MD.0000000000033604 (https://pubmed.ncbi.nlm.nih.gov/37115067/). 2. Gal, O., Baude, M., Deltombe, T., Esquenazi, A., Gracies, J. M., Hoskovcova, M., Rodriguez-Blazquez, C., Rosales, R., Satkunam, L., Wissel, J., Mestre, T., Sánchez-Ferro, Á., Skorvanek, M., Tosin, M. H. S., Jech, R., & members of the MDS Clinical Outcome Assessments Scientific Evaluation Committee and MDS Spasticity Study group (2024). Clinical Outcome Assessments for Spasticity: Review, Critique, and Recommendations. Movement disorders : official journal of the Movement Disorder Society, 10.1002/mds.30062. Advance online publication. https://doi.org/10.1002/mds.30062 (https://pubmed.ncbi.nlm.nih.gov/39629752/). 3. Gracies J. M. (2005). Pathophysiology of spastic paresis. I: Paresis and soft tissue changes. Muscle & nerve, 31(5), 535–551. https://doi.org/10.1002/mus.20284 (https://pubmed.ncbi.nlm.nih.gov/15714510/). 4. Gracies J. M. (2005). Pathophysiology of spastic paresis. II: Emergence of muscle overactivity. Muscle & nerve, 31(5), 552–571. https://doi.org/10.1002/mus.20285 (https://pubmed.ncbi.nlm.nih.gov/15714511/). 5. Gracies, J. M., Alter, K. E., Biering-Sørensen, B., Dewald, J. P. A., Dressler, D., Esquenazi, A., Franco, J. H., Jech, R., Kaji, R., Jin, L., Lim, E. C. H., Raghavan, P., Rosales, R., Shalash, A. S., Simpson, D. M., Suputtitada, A., Vecchio, M., Wissel, J., & Spasticity Study Group of the International Parkinson and Movement Disorders Society (2024). Spastic Paresis: A Treatable Movement Disorder. Movement disorders : official journal of the Movement Disorder Society, 10.1002/mds.30038. Advance online publication. https://doi.org/10.1002/mds.30038 (https://pubmed.ncbi.nlm.nih.gov/39548808/). 6. Guo, X., Wallace, R., Tan, Y., Oetomo, D., Klaic, M., & Crocher, V. (2022). Technology-assisted assessment of spasticity: a systematic review. Journal of neuroengineering and rehabilitation, 19(1), 138. https://doi.org/10.1186/s12984-022-01115-2 (https://pubmed.ncbi.nlm.nih.gov/36494721/). 7. He, J., Luo, A., Yu, J., Qian, C., Liu, D., Hou, M., & Ma, Y. (2023). Quantitative assessment of spasticity: a narrative review of novel approaches and technologies. Frontiers in neurology, 14, 1121323. https://doi.org/10.3389/fneur.2023.1121323 (https://pubmed.ncbi.nlm.nih.gov/37475737/). 8. Levin, M. F., Piscitelli, D., & Khayat, J. (2024). Tonic stretch reflex threshold as a measure of disordered motor control and spasticity - A critical review. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 165, 138–150. https://doi.org/10.1016/j.clinph.2024.06.019 (https://pubmed.ncbi.nlm.nih.gov/39029274/). 9. Li, S., Winston, P., & Mas, M. F. (2024). Spasticity Treatment Beyond Botulinum Toxins. Physical medicine and rehabilitation clinics of North America, 35(2), 399–418. https://doi.org/10.1016/j.pmr.2023.06.009 (https://pubmed.ncbi.nlm.nih.gov/38514226/). 10. Qin, Y., Qiu, S., Liu, X., Xu, S., Wang, X., Guo, X., Tang, Y., & Li, H. (2022). Lesions causing post-stroke spasticity localize to a common brain network. Frontiers in aging neuroscience, 14, 1011812. https://doi.org/10.3389/fnagi.2022.1011812 (https://pubmed.ncbi.nlm.nih.gov/36389077/). 11. Suputtitada, A., Chatromyen, S., Chen, C. P. C., & Simpson, D. M. (2024). Best Practice Guidelines for the Management of Patients with Post-Stroke Spasticity: A Modified Scoping Review. Toxins, 16(2), 98. https://doi.org/10.3390/toxins16020098 (https://pubmed.ncbi.nlm.nih.gov/38393176/). 12. Winston, P., Mills, P. B., Reebye, R., & Vincent, D. (2019). Cryoneurotomy as a Percutaneous Mini-invasive Therapy for the Treatment of the Spastic Limb: Case Presentation, Review of the Literature, and Proposed Approach for Use. Archives of rehabilitation research and clinical translation, 1(3-4), 100030. https://doi.org/10.1016/j.arrct.2019.100030 (https://pubmed.ncbi.nlm.nih.gov/33543059/).
N Engl J Med 2016;375:1242-1252Background: The first drug-eluting stent (DES) was approved by the FDA in 2003 following the publication of the RAVEL trial. Since then, newer generations of DES were developed and were tested in clinical trials. The majority of trials comparing DES to bare-metal stents (BMS) showed reduction in repeat revascularization with DES but no significant reduction in death or myocardial infarction. Following these publications, the use of DES grew rapidly and was used in more than two thirds of percutaneous coronary interventions (PCI) by 2010.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber.These trials, however, were very selective, had short follow up time (TAXUS-IV followed patients for 9 months and SPRIT IV followed patients for 12 months), and had limited power to assess hard outcomes.The NORSTENT trial investigators sought to compare DES to BMS in a more pragmatic design and follow patients for longer time.Patients: All patients who were undergoing PCI in Norway were assessed for enrollment. Patients had stable angina or acute coronary syndrome. Lesions were in native coronary arteries or bypass grafts.Patients were excluded if they had prior coronary stents, bifurcating lesions requiring a two-stent technique or life expectancy less than 5 years due to a medical condition other than coronary artery disease. Patients were also excluded if they had contraindications to dual antiplatelets or were taking warfarin.Baseline characteristics: The trial randomized 9,013 patients – 4,504 randomized to receive a DES and 4,509 to receive a BMS.The average age of patients was 63 years and 75% were men. Approximately 42% had hypertension, 54% had hyperlipidemia, 10% had prior myocardial infarction, 7% had prior CABG, 12% had diabetes, and 35% were current smokers.The indication for PCI was stable angina in 29% of the patients, unstable angina in 12% and STEMI or NSTEMI in 58%.Procedures: The study was open-label but outcomes assessment was blinded. Patients were randomly assigned in a 1:1 ratio to receive DES or BMS. Patients could receive several stents as clinically indicated but can only receive the assigned stent type during the index procedure.In all patients, aspirin 75 mg daily was given indefinitely while clopidogrel 75 mg daily was given for 9 months.Follow up visits were done as clinically appropriate without specification from the study protocol. Similarly, no routine follow up coronary angiography was performed.Endpoints: The primary outcome was a composite of all-cause death or spontaneous myocardial infarction. Secondary outcomes included repeat revascularization, stent thrombosis, major bleeding and health status based on the Seattle Angina Questionnaire.Clinical outcomes were collected by linking each patient unique national identification number to the Norwegian national patient registry.Analysis was performed based on the intention-to-treat principle. The study planned to enroll 8,000 patients to be followed for a median of 5 years. Assuming the 5-year event rate of the primary outcome to be 17%, the study would provide 93% power to detect 3% absolute risk difference between the study groups (rate ratio: 1.18). Due to lower than expected mortality, the sample size was increased to 9,000 patientsResults: Among the 20,663 patients who were assessed for eligibility, 12,425 met inclusion criteria. Among patients who met inclusion criteria, 9,013 were randomized. Figure 1 in the manuscript provides details for excluding patients and for not randomizing patients who met eligibility criteria. The most common reason for exclusion was prior PCI.The number of stents implanted per patient was 1.7 and more than 98% received the assigned stent type. The median follow up time was 5 years.The primary composite outcome of all-cause death or nonfatal spontaneous myocardial infarction was not significantly different between both treatment arms (16.6% with DES vs 17.1% with BMS, HR: 0.98; 95% CI: 0.88 - 1.09; p= 0.66).For the secondary outcomes – Hospitalization for unstable angina was similar between treatment groups (5.2% vs. 5.7%; p= 0.21). Stent thrombosis was lower with DES (0.8% vs 1.2%; p= 0.05). Target-lesion revascularization was also lower with DES (5.3% vs 10.3%; p< 0.001). Bleeding Academic Research Consortium (BARC) 3, 4 or 5 was similar between groups (5.5% vs 5.6%; p= 0.88).There was no significant difference in health status based on the Seattle Angina Questionnaire.There were no significant subgroup interactions.Conclusion: In patients undergoing PCI, the use of DES did not reduce the composite endpoint of death or spontaneous myocardial infarction compared to BMS. Target-lesion revascularization was reduced with DES with a number needed to treat of 20 patients.The findings of this study align with the results of other trials comparing DES to BMS. We have reviewed several key trials and included links to additional studies in this field below. Overall, DES significantly reduce target-lesion revascularization without significant effect on all-cause mortality or myocardial infarction.An important consideration in this and other related trials is that both stent types were studied using similar durations of dual antiplatelet therapy (DAPT) following PCI. For patients with stable angina, BMS typically require only one month of DAPT, while DES often necessitate three to twelve months. Since shorter durations of DAPT are generally safer for patients, a trial comparing DES with three to twelve months of DAPT compared to BMS with one month of DAPT would be insightful.A final teaching point is that less than 50% of screened patients were ultimately enrolled in this pragmatic trial, which had minimal exclusion criteria. It's not uncommon for trials to enroll less than 5% of screened patients which limits their external validity.* Other trials of DES vs BMShttps://pubmed.ncbi.nlm.nih.gov/21080780/https://pubmed.ncbi.nlm.nih.gov/22951305/Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe
In this episode of the Braun Performance & Rehab Podcast, Dan is joined by Dr. Sabrina Strickland and Dr. Andreas Gomoll to discuss the patellofemoral joint in detail, with considerations to instability, cartilage defects, and more. Dr. Sabrina Strickland is board certified in sports medicine and orthopedic surgery at HSS, where she specializes in patellofemoral surgery for instability, cartilage disease, ACL and meniscal surgery and shoulder surgery. She completed her residency and fellowship in sports medicine at HSS after completing medical school at Rush in Chicago. Prior to that, Dr. Strickland received her BA from Cornell University. Currently, Dr. Strickland is an associate professor of orthopedic surgery at Weill Cornell Medical College. She retired from her part-time position as the Chief of Orthopedics at the VA in 2012 after seven years of service. Dr. Strickland is also the co-founder of the HSS Patellofemoral Center. Dr. Strickland is a member of the American Academy of Orthopaedic Surgeons, the American Orthopaedic Society for Sports Medicine, and the Arthroscopy Association of North America. Her research focuses on the knee joint, specifically cartilage transplants, patellofemoral arthritis and instability, and ACL and meniscal repair. Prior to pursuing her medical career, Dr. Strickland was a ski instructor during college at Stratton and spent a year skiing in Crested Butte, Colorado where she still has a home. In her spare time, Dr. Strickland enjoys skiing, hiking near her home in Salisbury, CT, and paddle boarding on Twin Lakes. For more on Dr. Strickland, you can find her at https://www.hss.edu/physicians_strickland-sabrina.asp or by visiting her website https://sabrinastrickland.com/ Dr. Andreas Gomoll is double board certified in Orthopedic Surgery and Sports Medicine. His practice is devoted to preserving or restoring quality of life for patients with injuries to the knee and shoulder. He is widely recognized as one of the leading surgeons specializing in joint preservation with extensive experience in ACL reconstruction and meniscus repair, both performing primary procedures, as well as revision surgery for failed prior procedures. He also specializes in rotator cuff and biceps injuries. Dr. Gomoll is a Professor of Orthopedic Surgery, a Fellow of the American Academy of Orthopaedic Surgeons, the American Orthopaedic Society for Sports Medicine, and the International Cartilage Repair Society. He holds leadership positions in these and other US and international professional societies, as well as being on the editorial boards of several orthopedic journals. He has been awarded several Best Doctors designations, is a Castle Connolly Top Doctor, recipient of the Who is Who Humanitarian award, and was recognized as one of 16 stand-out sports knee surgeons in North America. He leads and participates in multiple surgical and non-surgical research trials of innovative new treatments for ligament, meniscus and cartilage damage, and has published over 100 articles and several books in this field. For more on Dr. Gomoll, you can find him at https://www.hss.edu/physicians_gomoll-andreas.asp or by visiting his website http://www.andreasgomollmd.com/ *SEASON 5 of the Braun Performance & Rehab Podcast is brought to you by Isophit. For more on Isophit, check out isophit.com and @isophit -BE SURE to use coupon code BraunPR25% to save 25% on your order! **Season 5 of the Braun Performance & Rehab Podcast is also brought to you by Oro Muscles. For more on Oro, check out www.oromuscles.com Episode Affiliates: MoboBoard: BRAWNBODY10 saves 10% at checkout! MedBridge: https://www.medbridgeeducation.com/brawn-body-training or Coupon Code "BRAWN" for 40% off your annual subscription! CTM Band: https://ctm.band/collections/ctm-band coupon code "BRAWN10" = 10% off! Check out everything Dan is up to by clicking here: https://linktr.ee/braun_pr Liked this episode? Leave a 5-star review on your favorite podcast platform --- Support this podcast: https://podcasters.spotify.com/pod/show/daniel-braun/support
En parlem amb un dels investigadors, Ramon Estruch i també amb Josep Maria Suelves, Cap de Prevenció i Control del Tabaquisme i les Lesions de l'Agència de Salut Pública de Catalunya
Osteochondritis dissecans (OCD) of the knee is a focal idiopathic alteration of subchondral bone and/or its precursor with risk for instability and disruption of adjacent cartilage. Treatment options focused on preventing premature osteoarthritis vary depending on multiple patient and lesion characteristics, including lesion mobility. In conclusion, age, effusion, and loss of motion can predict knee OCD lesion mobility at the time of arthroscopy. Education about lesion mobility can help with surgical planning and patient and family counseling. Click here to read the article.
DCB-BIF: Comparison of Noncompliant Balloon with Drug-Coated Balloon Angioplasty for Side Branch Stenosis After Provisional Stenting for Patients with True Coronary Bifurcation Lesions
Why are syphilis cases rising? Who is at risk and how does it spread? Learn about prevention of syphilis from Dr Teodora Elvira Wi in Science in 5.
Join us in this expert interview of 2024 PAD guideline Co-Author Dr. Van de Water (Maastricht) and 2023 ZILVERPASS Author Dr. Bosiers (Bern) in this timely debate.References:- Bosiers M, De Donato G, Torsello G, et al. ZILVERPASS study: ZILVER PTX Stent vs Bypass Surgery in Femoropopliteal lesions. J Cardiovasc Surg. 2023. https://doi.org/10.23736/S0021- 9509.23.12607- RJ Vossen, TM Fokkema, AC Vahl, and R Balm. Systematic review and meta-analysis comparing the autogenous vein bypass versus a prosthetic graft for above-the-knee femoropopliteal bypass surgery in patients with intermittent claudication. Vascular. Sept 6 2022. Vol 32 issue 1. - Maxime Dubosq-Lebaz , Audrey Fels , Gilles Chatellier , Yann Gouëffic Systematic Review and Meta-analysis of Clinical Outcomes After Endovascular Treatment in Patients With Femoropopliteal Lesions Greater Than 150 mm. J Endovasc Ther. 2023 Sep 30:15266028231202709.- Alik Farber et al. Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia (BEST-CLI). N Engl J Med. 2022 Dec 22;387(25):2305-2316.- Andrew W Bradbury et al. A vein bypass first versus a best endovascular treatment first revascularisation strategy for patients with chronic limb threatening ischaemia who required an infra-popliteal, with or without an additional more proximal infra-inguinal revascularisation procedure to restore limb perfusion (BASIL-2): an open-label, randomised, multicentre, phase 3 trial. Lancet. 2023 May 27;401(10390):1798-1809.- Nordanstig et al. European Society for Vascular Surgery (ESVS) 2024 Clinical Practice Guidelines on the Management of Asymptomatic Lower Limb Peripheral Arterial Disease and Intermittent Claudication. Eur J Vasc Endovasc Surg (2024) 67, 9e96)References:- Bosiers M, De Donato G, Torsello G, et al. ZILVERPASS study: ZILVER PTX Stent vs Bypass Surgery in Femoropopliteal lesions. J Cardiovasc Surg. 2023. https://doi.org/10.23736/S0021- 9509.23.12607- RJ Vossen, TM Fokkema, AC Vahl, and R Balm. Systematic review and meta-analysis comparing the autogenous vein bypass versus a prosthetic graft for above-the-knee femoropopliteal bypass surgery in patients with intermittent claudication. Vascular. Sept 6 2022. Vol 32 issue 1. - Maxime Dubosq-Lebaz , Audrey Fels , Gilles Chatellier , Yann Gouëffic Systematic Review and Meta-analysis of Clinical Outcomes After Endovascular Treatment in Patients With Femoropopliteal Lesions Greater Than 150 mm. J Endovasc Ther. 2023 Sep 30:15266028231202709.- Alik Farber et al. Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia (BEST-CLI). N Engl J Med. 2022 Dec 22;387(25):2305-2316.- Andrew W Bradbury et al. A vein bypass first versus a best endovascular treatment first revascularisation strategy for patients with chronic limb threatening ischaemia who required an infra-popliteal, with or without an additional more proximal infra-inguinal revascularisation procedure to restore limb perfusion (BASIL-2): an open-label, randomised, multicentre, phase 3 trial. Lancet. 2023 May 27;401(10390):1798-1809.- Nordanstig et al. European Society for Vascular Surgery (ESVS) 2024 Clinical Practice Guidelines on the Management of Asymptomatic Lower Limb Peripheral Arterial Disease and Intermittent Claudication. Eur J Vasc Endovasc Surg (2024) 67, 9e96)
OCCUPI – Optical Coherence Tomography-Guided Coronary Intervention in Patients with Complex Lesions
N Engl J Med 2022;386:128-137Background: Patients with three-vessel coronary artery disease have better outcomes when revascularization is performed using coronary artery bypass grafting (CABG) compared to percutaneous coronary intervention (PCI), as seen in the SYNTAX and FREEDOM trials. Fractional flow reserve (FFR) was not required and was not routinely performed in these trials.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.The Fractional Flow Reserve versus Angiography for Multivessel Evaluation (FAME) 3 trial sought to compare the outcomes of FFR-guided PCI vs CABG in patients with three-vessel coronary artery disease.Patients: Eligible patients had three-vessel coronary artery disease defined as 50% or more stenosis, by visual estimation, in any of the three major coronary arteries or major branches. Lesions had to be amenable to revascularization by PCI and CABG as determined by the heart team.Major exclusion criteria were left main disease, cardiogenic shock, STEMI within 5 days, active NSTEMI with cardiac troponin still rising, left ventricular ejection fraction
Keep track of the lunar cycle each month and observe whether your child's symptoms, or your own, intensify in the days leading up to and following the full moon. [This is podcast episode #205]. The full moon has long been associated with a range of mysterious phenomena, from sleep disturbances to heightened emotions. But one of the more intriguing aspects is that full moons can increase parasite activity in humans. Is there any truth to this claim, or is it just another lunar myth? Let's explore how the moon's phases, particularly the full moon, might impact the behavior of parasites and what science has to say about it. First Of All, How Do We Get Parasites? Common ways we get parasites are from inhaling them from the air we breathe, in the food we eat, drinking water, swimming or bathing in contaminated water, and through our skin. Lesions in the skin, especially on the feet, allow for easy entrance into the body. Animals carry different parasites that they may pass onto humans. Plus, poor hygiene also plays a big role. Understanding Parasites and Their Behavior Parasites are organisms that live off a host, relying on them for nutrients and shelter. Human parasites include a range of organisms such as protozoa (like Giardia), helminths (such as tapeworms and roundworms), and external parasites like lice. Their lifecycle often depends on factors such as environmental changes, the host's immune system, and how many have noticed, even the lunar cycle. While parasite infestations can go unnoticed for some time, they can lead to significant health issues, including gastrointestinal problems, fatigue, and weakened immune responses. Understanding how these organisms behave is crucial to preventing and managing infections. Click Here or Click the link below for more details! https://naturallyrecoveringautism.com/205
Acetabular lesions present unique challenges for interventionalists due to their location within the pelvis. In this episode of the BackTable Podcast, host Dr. Jacob Fleming interviews Dr. Jason Levy, an experienced practitioner in musculoskeletal interventional oncology based in Atlanta, Georgia, about techniques for ablating acetabular lesions. --- This podcast is supported by an educational grant from: Medtronic https://www.medtronic.com/en-us/index.html --- SYNPOSIS The doctors discuss the unique considerations involved in treating the acetabulum, including its susceptibility to various axial loading, shear, and torsion forces. Dr. Levy prefers to use radiofrequency ablation combined with cement augmentation to enhance joint stability. He outlines the procedural steps and shares his preferred imaging methods. Additionally, he addresses potential complications, such as instability from inadequate cement delivery, cement leakage into the hip joint space, and avascular necrosis. Throughout the episode, the doctors emphasize the importance of collaboration with orthopedic oncologists and staying updated on current research in musculoskeletal interventional oncology. --- TIMESTAMPS 00:00 - Introduction 05:11 - Unique Considerations for Acetabular Lesions 09:06 - Collaboration with Orthopedic Oncologists 13:10 - Anatomy and Procedural Steps 24:40 - Preventing Complications 35:25 - Concluding Thoughts --- RESOURCES BackTable MSK Ep. 17- Multidisciplinary Approach to Treating Spinal Metastases with Dr. Jason Levy and Dr. Amir Lavaf: https://www.backtable.com/shows/msk/podcasts/17/multidisciplinary-approach-to-treating-spinal-metastases BackTable VI Ep. 68- RF Ablation Therapy for Bone Metastases with Dr. Jason Levy and Dr. Sandeep Bagla: https://www.backtable.com/shows/vi/podcasts/68/rf-ablation-therapy-for-bone-metastases BackTable MSK Ep. 12- Ortho/IR Collaboration in Private Practice: https://www.backtable.com/shows/msk/podcasts/12/ortho-ir-collaboration-in-private-practice Radiofrequency Ablation for the Palliative Treatment of Bone Metastases: Outcomes from the Multicenter OsteoCool Tumor Ablation Post-Market Study (OPuS One Study): https://pubmed.ncbi.nlm.nih.gov/33129427/ Hip Joint Distraction Technique during Cryoablation of Acetabular Bone Tumor to Prevent Femoral Head Osteonecrosis: https://www.jvir.org/article/S1051-0443(22)01119-8/fulltext
Acetabular lesions present unique challenges for interventionalists due to their location within the pelvis. In this episode of the BackTable Podcast, host Dr. Jacob Fleming interviews Dr. Jason Levy, an experienced practitioner in musculoskeletal interventional oncology based in Atlanta, Georgia, about techniques for ablating acetabular lesions. --- This podcast is supported by an educational grant from: Medtronic https://www.medtronic.com/en-us/index.html --- SYNPOSIS The doctors discuss the unique considerations involved in treating the acetabulum, including its susceptibility to various axial loading, shear, and torsion forces. Dr. Levy prefers to use radiofrequency ablation combined with cement augmentation to enhance joint stability. He outlines the procedural steps and shares his preferred imaging methods. Additionally, he addresses potential complications, such as instability from inadequate cement delivery, cement leakage into the hip joint space, and avascular necrosis. Throughout the episode, the doctors emphasize the importance of collaboration with orthopedic oncologists and staying updated on current research in musculoskeletal interventional oncology. --- TIMESTAMPS 00:00 - Introduction 05:11 - Unique Considerations for Acetabular Lesions 09:06 - Collaboration with Orthopedic Oncologists 13:10 - Anatomy and Procedural Steps 24:40 - Preventing Complications 35:25 - Concluding Thoughts --- RESOURCES BackTable MSK Ep. 17- Multidisciplinary Approach to Treating Spinal Metastases with Dr. Jason Levy and Dr. Amir Lavaf: https://www.backtable.com/shows/msk/podcasts/17/multidisciplinary-approach-to-treating-spinal-metastases BackTable VI Ep. 68- RF Ablation Therapy for Bone Metastases with Dr. Jason Levy and Dr. Sandeep Bagla: https://www.backtable.com/shows/vi/podcasts/68/rf-ablation-therapy-for-bone-metastases BackTable MSK Ep. 12- Ortho/IR Collaboration in Private Practice: https://www.backtable.com/shows/msk/podcasts/12/ortho-ir-collaboration-in-private-practice Radiofrequency Ablation for the Palliative Treatment of Bone Metastases: Outcomes from the Multicenter OsteoCool Tumor Ablation Post-Market Study (OPuS One Study): https://pubmed.ncbi.nlm.nih.gov/33129427/ Hip Joint Distraction Technique during Cryoablation of Acetabular Bone Tumor to Prevent Femoral Head Osteonecrosis: https://www.jvir.org/article/S1051-0443(22)01119-8/fulltext
One of the most common clinical presentations to ophthalmologist is 'the eyelid lesion'. While sometimes it might seem obvious what the diagnosis is, other times it's tough to make a spot diagnosis or even to decipher whether the lesion is concerning or not. So what are some helpful examination tips to help us discern the benign from the malignant? Oculoplastics specialist Dr. Lisa Jagan joins the podcast to share an effective approach on how to decide what types of eyelid lesions warrant a biopsy. This episode is sponsored by Sun Pharma Canada - https://sunpharma.com/canada/Check out Lid Express to help expedite a patient's referral for an eyelid lesion - https://clarityeye.ca/services/lid-express/ Become a supporter of this podcast: https://www.spreaker.com/podcast/blind-spot-the-eye-doctor-s-podcast--5819306/support.
OCT vs. Angiography for Guidance of Calcified Lesions PCI: The CALIPSO Trial
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Welcome to the Orthobullets Podcasts. Today's show is Podiums, where we feature expert speakers from live medical events. Today's episode will feature Dr. Brian J. Cole from Midwest Orthopaedics at Rush, and is titled "The Natural History of Cartilage Lesions, What Do We Really Know?"
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In this episode, we discuss osteochondral lesions of the talus with Dr John G. Kennedy. We talk about everything from the history and physical aspects of these lesions to cutting-edge operative treatments and outcomes. Click here for show notes Dr. Kennedy is a world renowned Foot and Ankle surgeon, and a leading expert in cartilage injuries. He co-founded the ICCRA, which has since set the gold standard in treatment alogorithms for ankle cartilage surgery. His interests include regenerative medicine and minimally invasive Nano-arthroscopy. Dr. Kennedy was the first surgeon to perform in-office Nano-arthroscopy. Currently, he is the chief of the Division of Foot and Ankle Surgery and Director of the Foot and Ankle Center at NYU Langone Department of Orthopedic Surgery. Dr. Kennedy continues to train surgeons from around the world and his research team has published over 250 peer-reviewed articles and presented over 2000 times around the globe. Goal of episode: To develop a baseline knowledge of osteochondral lesions of the talus. In this episode, we discuss: Epidemiology Etiology History Imaging Non-op treatment Operative treatment and many more This episode is sponsored by the American Academy of Orthopaedic Surgeons: Filled with content that has been vetted by some of the top names in orthopaedics, the AAOS Resident Orthopaedic Core Knowledge (ROCK) program sets the standard for orthopaedic education. Whether ROCK is incorporated into your residency curriculum, or you use it independently as a study tool, the educational content on ROCK is always free to residents. You'll gain the insights and confidence needed to ensure a successful future as a board-certified surgeon who delivers the best patient care. Log on at https://rock.aaos.org/.
Summary This conversation discusses common oral lesions, specifically dry mouth, candidiasis (fungal infection of the mouth), and canker sores (aphthous ulcers). The prevalence, causes, symptoms, and treatment options for each condition are explored. Dry mouth can be caused by medications and can lead to dental issues and bad breath. Candidiasis is an opportunistic infection that can be triggered by an imbalance in the oral cavity. Canker sores are the most common oral lesion and can be caused by nutritional deficiencies and certain toothpaste ingredients. Treatment options include medications, natural remedies, and lifestyle changes. Keywords oral lesions, dry mouth, xerostomia, candidiasis, fungal infection, canker sores, aphthous ulcers, prevalence, causes, symptoms, treatment options. Takeaways Dry mouth, or xerostomia, is a common condition that can be caused by medications and can lead to dental issues and bad breath. Candidiasis is an opportunistic fungal infection that can occur in the mouth due to an imbalance in the oral cavity. Canker sores, or aphthous ulcers, are the most common oral lesion and can be caused by nutritional deficiencies and certain toothpaste ingredients. Treatment options for these oral lesions include medications, natural remedies, and lifestyle changes. Titles Understanding and Managing Dry Mouth Preventing and Treating Candidiasis in the Mouth Sound Bites "What is fricking spit? What is saliva? It's really water." "Dry mouth can lead to fungal infections, dental caries, dysphagia, and bad breath." "Fungal infections in the mouth are opportunistic and require an imbalance in the oral cavity to occur." Chapters 00:00 Introduction and Overview 02:15 Dry Mouth: Causes, Symptoms, and Effects 08:02 Candidiasis: Opportunistic Fungal Infection 11:18 Canker Sores: Common Oral Lesion
The spinal cord serves as the main communication highway between the brain and body. Did you know that 80% of people with multiple sclerosis have spinal cord lesions on MRI? These lesions can disrupt specific neural pathways, leading to common MS symptoms like numbness, weakness, impaired coordination, balance issues, bladder problems, constipation, and sexual dysfunction. For instance, damage to the corticospinal tract on one side of the spinal cord can weaken an arm or leg. A remarkable autopsy study revealed that nearly 90% of people with MS still had active inflammation in the spinal cord. This finding brings new hope for potential treatments, even for older and progressive MS patients. Advances in imaging technology, including more powerful MRI scanners (3 Tesla and higher), are enhancing our ability to see inside the spinal cord, which is as thin as a pinky finger. Improved spinal cord imaging is driving the development of new therapies in clinical trials and helping identify those at risk for worsening disability, ultimately guiding better treatment decisions. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Gabriele De Luca MD DPhil, Professor of Clinical Neurology and Experimental Neuropathology, University of Oxford, United Kingdom Bruce Cree MD PhD, Professor of Neurology at University of California, San Francisco School of Medicine
Results of the Magnesium BRS in Complex Lesions: Data from the IT-Masters Registry
Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
In this episode, we dive into the complexities of Bartonella, a genus of gram-negative, facultative intracellular bacteria known for its ability to evade the immune system and persist in host cells such as endothelial cells and erythrocytes. We explore the specific pathogenesis mechanisms of Bartonella henselae, including its interaction with cell adhesion molecules which facilitate its intracellular entry and survival. Additionally, we discuss the clinical manifestations and epidemiological significance of Bartonella as a common co-infection in Lyme disease patients, emphasizing its role in chronic symptoms such as swollen lymph nodes and vascular-related skin lesions. Topics: 1. Introduction - Overview of Chronic Inflammatory Response Syndrome and biotoxin illness. 2. Overview of Bartonella - Definition and general characteristics of Bartonella as a genus of gram-negative bacteria. - Explanation of facultative intracellular pathogens and their survival mechanisms. 3. Transmission Modes - Common vectors: fleas, lice, ticks, and the role of arthropod vectors in Bartonella transmission. - Other transmission routes: animal scratches/bites (particularly from cats), contaminated needles / blood transfusions. 4. Pathogenesis of Bartonella - Initial entry and dissemination through the circulatory system. - Predilection for endothelial cells and specific mechanisms of endothelial cell invasion. - Role of Bartonella adhesin A and its interaction with fibronectin and integrins. - Signaling pathways and cytoskeletal changes leading to endocytosis. 5. Immune Evasion and Infection Persistence - Intracellular residency in endothelial cells to evade neutrophils. - Ability to infect and persist in red blood cells and macrophages. - Impact on lymph nodes and immune response leading to swollen lymph nodes. 6. Clinical Manifestations - Specific diseases caused by different Bartonella species: - Bartonella henselae: Cat scratch fever - Bartonella quintana: Trench fever - Bartonella bacilliformis: Carrion's disease - Symptoms of Bartonella infections, including swollen lymph nodes, bone pain, and skin markings. - Severe cases leading to Bacillary Angiomatosis and vascular-related skin lesions. 7. Summary and Implications - Recap of Bartonella's impact as a Lyme co-infection. - Reminder of the diversity of Bartonella species and their varied clinical presentations. - Importance of tailored medical guidance due to the complexity of co-infections. Thank you to our episode sponsor: Liver Medic Use code Chloe20 to save 20% on "Leaky Gut Repair" Brendan's YouTube Channel https://x.com/livermedic Thanks for tuning in! Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellness Follow Chloe on TikTok @chloe_c_porter Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support
Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief
OCD Lesions are unique injuries to both cartilage and bone and not only occur in adults, but also often occur in the bodies of today's youth. It's time to find out more from a series of answers, details and lightbulb-conjuring lessons from 3 orthopedic surgeons inside this episode of The 6 to 8 Weeks Podcast.
Phil Starr is a Professor of Neurological Surgery at University of California, San Francisco and a developer of implantable brain devices. At UCSF, he co-directs a multidisciplinary neurology/neurosurgery movement disorders clinic together with Dr. Jill Ostrem. I've been a long-time admirer of Phil's work and in this conversation we blaze through quite a few of his numerous publications. One key breakthrough and invention of Phils work has been to include Ecog recordings – both intraoperatively but also chronically – to investigate brain signals in various states. We talk about the Open Mind Consortium, Mentorship and the cross-pollination between academia and industry. One key highlight of Phils work is a paper which was accepted for publication in Nature Medicine, at the time of recording this just yesterday. In it, the three co-first authors Carina Oehrn, Stephanie Cernera and Lauren Hammer demonstrate the chronic use of a newly identified cortical physiomarker, which is now referred to as the finely tuned gamma activity. I hope you enjoy this conversation as much as I did, and thank you for tuning into Stimulating Brains!
Rebecca Le, MD discusses an article detailing how core needle biopsy may help avoid a missed or delayed cancer diagnosis in pulmonary lesions with cystic airspaces. ARTICLE TITLE - CT-Guided Core-Needle Biopsy of Pulmonary Lesions Associated With Cystic Airspaces: A Case-Control Study
Follow along with our Nailed it Board/OITE Podcast Companion book. Get your copy by clicking here >> https://a.co/d/cr4i8nD Enjoy another episode from our board review series featuring Dr. Cole and Dr. Woolwine. This episode is sponsored by the American Academy of Orthopaedic Surgeons: Filled with content that has been vetted by some of the top names in orthopaedics, the AAOS Resident Orthopaedic Core Knowledge (ROCK) program sets the standard for orthopaedic education. Whether ROCK is incorporated into your residency curriculum, or you use it independently as a study tool, the educational content on ROCK is always free to residents. You'll gain the insights and confidence needed to ensure a successful future as a board-certified surgeon who delivers the best patient care. Log on at https://rock.aaos.org/.
In this episode, we review the high-yield topic of Spinal Cord Lesions from the Neurology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets Linkedin: https://www.linkedin.com/company/medbullets
Follow along with our Nailed it Board/OITE Podcast Companion book. Get your copy by clicking here >> https://a.co/d/cr4i8nD Enjoy another episode from our board review series featuring Dr. Cole and Dr. Woolwine. This episode is sponsored by the American Academy of Orthopaedic Surgeons: Filled with content that has been vetted by some of the top names in orthopaedics, the AAOS Resident Orthopaedic Core Knowledge (ROCK) program sets the standard for orthopaedic education. Whether ROCK is incorporated into your residency curriculum, or you use it independently as a study tool, the educational content on ROCK is always free to residents. You'll gain the insights and confidence needed to ensure a successful future as a board-certified surgeon who delivers the best patient care. Log on at https://rock.aaos.org/.
In this episode, we join Dr. Emily Dawson, helping us tackle some of the ductal dependent pathologies we may see in emergency medicine. This episode was recorded live at ICEP24 in Chicago. Presentation content... https://www.icep.org/wp-content/uploads/2024/04/09-Peds-Cardiology-Dawson.pdf
Join me for a summary podcast exploring the topic of white spot lesions, and up-to-date research looking at how to manage lesions when they occur, when the right time is to treat the patient, and what minimally evasive options can be used in clinic. This was an excellent lecture from Gayle Glenn earlier this year at the AAO winter meeting. Four treatment options are discussed, Fluoride, CPPACP (Mi paste), resin infiltrate and microabrasion. Whitespot lesion background WSL Definition - subsurface deminieralization, intact outer layer, 1st sign of carious lesions Remineralisation – no additional agents Most rapid repair first 6 weeks without use of additional agents · Up to 6 months spontaneous improvement with good oral hygiene · Recommend 3-6 months monitor after debond: BEFORE consider additional treatment Fluoride · Decrease enamel dissolution · Increase reminerazation · Formation of fluorapatite · Products o Fl varnish reduce WSL occuring by 44%: § require plaque removal and wire removal § Not often used in clinical practice and requires repeat application · TREATMENT WSL o Fluoride low dose (toothpaste) o High Fluoride – hyperminerasied surface layer forms = seal off subsurface layer which remains demineralized. Bishara 2008 Resin infiltration Gray 2002 · Remove outer hypomineralised area with 15% HFL o Infiltrate with low viscosity o Improves aesthetics o Arrest lesion – however some demineralisation may remain o Lack long-term evidence o Most effective in research (RR:121.50, 95%CI: 51.45-191.55 Jiang 2023) MI paste (CPPACP) Frencken 2012 · Milk protein derived · Stabilizes Ca PO4 – ideal of for formed WSL · Creates Ca PO4 reservoir around bracket · Applied: o Brush above and below bracket or finger o Distributed by the tongue o Can be swallowed o Avoid eat and drink 30-60 minutes · Effectiveness for reminersation o Evidence unclear – conflicting sustematic reviews AlBukaiki 2023 no difference, same year Jiang 2023, it is effective, however exceptionally large range of values (RR:49.69, 95%CI: 0.87-98.51 and although RCTs, limited to assessing premolars only and different methods of assessment and duration of treatment. · TREATMENT FOR WSL o Wait 3-6 months following removal of braces o In retainer 3-5 minutes o Rinse out o Nothing to eat 30-60 minutes Microabrasion · Combination of acid and abrasive particles · Burinsh into enamel with slow speed handpiece · opalustre = 6% HCL + silica (low particle size, lower concentration with larger particle size than prophy paste = 12-160 particle size 1986 Krol) o 1 mm size of use o Burnished in using a polishing cup and slow handpiece o 1 minute · Not widely accepted o Partly due to variations in protocol o Use of rubber dam · Microabrasion and CPP-ACP proposed idea Ardu 2007 2022 Lammert · CPP-ACP both sides, with half of mouth also receiving 1 visit of microabrasion · After 6 months post debonding · Evaluate and repeat up to 8 times · Results o Mi paste group 9.3-8.1 size of lesion – statistically significant o Microabrasion and Mi paste group § 13.2 – 4.3 and reduce to 2.1 · Most improvement immediate after microabrasion o Compared difference of size of the initial lesion § 5.5 x reduction in CPPACP § 7.4 X reduction in microabrasion Clinical implication · Microabrasion = significant clinical time o Up to 8 minutes per tooth, can be up to 1 hour o Therefore clinical application § Perhaps isolated 1 or 2 teeth Conclusions: 1. Patients with WSL are usually not great compliers, giving additional products which require significant compliance, is practising research in isolation. 2. Microabrasion takes nearly 1 hour, role in clinical practice limited to isolated areas
Follow along with our Nailed it Board/OITE Podcast Companion book. Get your copy by clicking here >> https://a.co/d/cr4i8nD Enjoy another episode from our board review series featuring Dr. Cole and Dr. Woolwine. This episode is sponsored by the American Academy of Orthopaedic Surgeons: Filled with content that has been vetted by some of the top names in orthopaedics, the AAOS Resident Orthopaedic Core Knowledge (ROCK) program sets the standard for orthopaedic education. Whether ROCK is incorporated into your residency curriculum, or you use it independently as a study tool, the educational content on ROCK is always free to residents. You'll gain the insights and confidence needed to ensure a successful future as a board-certified surgeon who delivers the best patient care. Log on at https://rock.aaos.org/.
Starting a private practice and the Direct Care model with Dr. Stephen Lewellis - Juvenile gangrenous vasculitis of the scrotum - Midline lesions and when to image - Dermasphere clip show: Episodes 121-130! Find Stephen Lewellis on the web! - https://retinoids.lewellismd.com/posts - https://lewellismd.com/podcast/ Luke's urticaria CME event: https://aaaai.gathered.com/invitation?ref=4openn7e7A Michelle's prurigo nodularis CME event: https://horizoncme.gathered.com/invitation?ref=GELe3oAe69 Want to donate to the cause? Do so here! http://www.uofuhealth.org/dermasphere Check out our video content on YouTube: https://www.youtube.com/@dermaspherepodcast and VuMedi!: https://www.vumedi.com/channel/dermasphere/ The University of Utah's Dermatology ECHO: https://physicians.utah.edu/echo/dermatology-primarycare - Connect with us! - Web: https://dermaspherepodcast.com/ - Twitter: @DermaspherePC - Instagram: dermaspherepodcast - Facebook: https://www.facebook.com/DermaspherePodcast/ - Check out Luke and Michelle's other podcast, SkinCast! https://healthcare.utah.edu/dermatology/skincast/ Luke and Michelle report no significant conflicts of interest… BUT check out our friends at: - Kikoxp.com (a social platform for doctors to share knowledge) - https://www.levelex.com/games/top-derm (A free dermatology game to learn more dermatology!)
Welcome to our Fifth citation classics from our Sports team! The goal of these episodes are to go over the most cited articles in a certain topic over the past 15-20 years to give learners an idea of what articles are being read and what are some of the important studies out there to read! In this episode, we go over articles on OCD lesions of the knees and treatment. Link to post: https://naileditortho.com/sports05 Sports Team! Tucker Peabody - PGY 2- Ohio Health Dr. Ehab Nazzal PGY-3 Pittsburg Tyler Thorne, MD Tariq Said- MS6 - Missouri Wendell "Cody" Cole- PGY- 5 Tulane University. This episode is sponsored by Arthrex: Arthrex has been helping surgeons treat their patients better for more than 40 years. Differentiate your practice by offering the Nano Experience, which combines patient comfort with leading edge, extremely minimally invasive technology. Deeply committed to surgeon support and patient education, Arthrex has also introduced TheNanoExperience.com, a patient resource illustrating the science and benefits of Nano arthroscopy, detailing the wide variety of applications, and directing patients to surgeons in their area. Visit Nano.Arthrex.com to learn more about enhancing your practice and providing optimal patient outcomes with this game-changing technology.
Macroscopic Skin Lesions A thorough skin examination should be performed annually to assess for new or changing macroscopic skin lesions. It is critically important to be able to identify and describe normal and abnormal skin and to note your findings carefully, because a change in an existing skin lesion is the most common sign of skin cancer, including deadly ones like melanoma. In this discussion, we will describe the specific ways in which you document skin lesions, using a vocabulary that other clinicians will understand. After listening to this AudioBrick, you should be able to: Explain the importance of physical examination of the skin. Describe skin lesions, explaining and illustrating each of the following: size, type (eg, vesicle, bulla), color, configuration (eg, annular, targetoid, discoid), arrangement (eg, solitary, grouped, linear, reticular), and distribution and location. You can also check out the original brick on Macroscopic Skin Lesions from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com. You will get 5 days of full access to our Rx360+ program, including Step 1 Qmax, Flash Facts, Express Videos, a digital version of First Aid for the USMLE Step 1, and nearly 800 Rx Bricks. After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology. *** If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts. It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/
OCD Lesions are unique injuries to both cartilage and bone and not only occur in adults, but also often occur in the bodies of today's youth. It's time to find out more from a series of answers, details and lightbulb-conjuring lessons from 3 orthopedic surgeons inside this episode of The 6 to 8 Weeks Podcast. Connect with The 6-8 Weeks Podcast: There's a LOT of detail included in this program. Do you want to share YOUR perspective about it? Connect with The 6-8 Weeks Podcast Now! Subscribe to, Like and Share The 6-8 Weeks Podcast Everywhere: The Detailed Shownotes for This Episode of The 6-8 Weeks Podcast: -- -- What is an Osteochondrial Lesion? https://www.sportsmedicinenewyork.com/osteochondral-lesions-ankle-ankle-orthopedic-foot-ankle-surgeon-new-york-ny.html -- What is Cartalige? https://my.clevelandclinic.org/health/body/23173-cartilage -- What is Bone? https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/bones -- What is an X-Ray? https://my.clevelandclinic.org/health/diagnostics/21818-x-ray -- What is the Capitellum? https://radiopaedia.org/articles/capitellum Timestamps for This Episode of The 6-8 Weeks Podcast: 00:00 Knee pain and swelling, potentially from injury or degeneration. It can manifest as weakness and restricted motion, possibly due to a loose piece in the joint. 06:10 Ankle injuries can occur traumatically or atraumatically, with ankle sprains often affecting the outside or inside part of the talus bone. Treatment options for knee and elbow injuries are generally effective, but data for ankle osteochondral defects (OCDs) remains limited, and the appropriate treatment approach is still unclear. 08:44 Smaller knee lesions located in atypical areas have a better chance of healing, as they are not subjected to as much stress. However, lesions in common high-stress areas, such as the medial part of the knee, may struggle to heal. Non-operative treatments like bracing may be challenging for active children, leading some families to opt for early surgical intervention, particularly for older children, to avoid a long drawn-out treatment process. 11:02 Kids' cartilage repair relies on piece condition and age, with early intervention yielding higher success rates. However, invasive techniques may not be worth the risk. 13:54 Allograft is recommended for larger, younger lesions. Seek medical advice if symptoms worsen, even in younger individuals. Various treatment options are available. Expert guidance is crucial due to the complexity and conflicting information online. Connect with the Hosts of The 6-8 Weeks Podcast: It's never been easier to connect with the hosts of The 6-8 Weeks Podcast. Read on below to share your perspectives on this episode of The 6-8 Weeks Podcast. === Connect with Dr. Brian Feeley: On the Web -- On X === Connect with Dr. Nirav Pandya: On the Web:-- On X: === Connect with Dr. Drew Lansdown: On the Web
❌❌❌در قسمت صد و بیست وششم دنتکست، مقاله ی ضایعات NCCL یا noncarious cervical lesions رو ادامه میدیم.این مقاله توسط Goodacre نوشته شده که قبلا هم از این نویسنده دنتکست داشتیم که خیلی مباحث مفیدی مطرح شده بود.مقاله ی مروری خوبیه،این ضایعات رو از جهات مختلف بررسی میکنه و درنهایت گایدلاین کلینیکی برای درمانشون ارائه میکنه.این قسمت دوم از سری NCCL هست.
Bradley Burnam woke up one morning, looked in the mirror and found one ear twice it's normal size and his face swollen and discolored. He would spend the next several years in and out of the hospital fighting a relentless infection that would not respond to available treatments. The experience took him from patient to mad scientist, to biotech company founder. In this episode, Bradley takes us through his desperate journey to find a cure. We also talk with the leader of an organization helping to get more antimicrobials to the marketplace.Follow us on LinkedIn, X, Facebook and Instagram. Visit us at https://www.bio.org/
In this episode, host Dr. Aaron Fritts is joined by interventional cardiologists Dr. Sameh Sayfo (Baylor Scott & White in Plano, TX) and Dr. Nicolas Shammas (Cardiovascular Medicine in Davenport, IA) for a discussion about critical limb ischemia (CLI) and the use of lasers in below-the-knee (BTK) treatment. To start, Dr. Shammas explains that infrapopliteal disease is difficult to treat due to the high rate of total occlusions and the high degree of medial calcinosis. Next, he gives an introduction to laser atherectomy for certain plaque locations and morphologies, and he describes previous studies that have shown its efficacy for calcified lesions. Intravascular ultrasound (IVUS) can also help guide vessel sizing, plaque morphology, and appropriate device selection. Dr. Shammas believes that the current atherectomy devices on the market are easy to learn to use and can be incorporated into any CLI program. The doctors discuss the ongoing multicenter study on outcomes of the Auryon laser atherectomy system in CLI patients. Dr. Shammas reviews the study design, proposed endpoints, and current data on 30 day outcomes. We end the episode with advice on building a strong CLI program, which includes multidisciplinary collaboration, advocating for resources, a variety of different tools, and appropriate management of cardiovascular risk factors. --- CHECK OUT OUR SPONSOR AngioDynamics Auryon System https://www.auryon-system.com/ --- SHOW NOTES 00:00 - Introduction 04:18 - Current Treatment Limitations for Infrapopliteal Disease 07:38 - Laser Atherectomy for Calcified Lesions 12:10 - Learning Curve for Laser Atherectomy Devices 15:38 - 30-Day Results of the Auryon BTK Study 23:35 - Technical Approach and Tools for Infrapopliteal Segments 29:00 - Upcoming Developments in CLI Treatment 31:33 - Advice for Building a CLI Program --- RESOURCES Calcium 360 Trial: https://pubmed.ncbi.nlm.nih.gov/22891826/ Auryon Laser Atherectomy System: https://www.angiodynamics.com/product/auryon/ Nexcimer Laser Atherectomy System: https://www.usa.philips.com/healthcare/product/HCIGTDPHLLSRSYSTM/laser-system-hcigtdphllsrsystm 30-Day Results of the Auryon BTK Study: https://www.jacc.org/doi/10.1016/j.jacc.2023.09.194 Midwest Cardiovascular Research Foundation: http://www.mcrfmd.com/ Life-BTK Study: https://www.cardiovascular.abbott/us/en/patients/treatments-therapies/peripheral-artery-disease/life-btk.html Promise II Study: https://www.nejm.org/doi/full/10.1056/NEJMoa2212754 BackTable Ep. 350- Building a CLI Program with Dr. Zola N'Dandu: https://www.backtable.com/shows/vi/podcasts/350/building-a-cli-program