Podcasts about Prevalence

Number of disease cases in a given population at a specific time

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Order of Man
DR. ERIC COLE | How Cyberthreats Endanger Men and Their Families

Order of Man

Play Episode Listen Later Jul 15, 2025 61:34


Considering how often we utilize technology, we don't spend as nearly as much time as we should protecting ourselves against the inherent vulnerabilities and bad actors who would exploit the very tools designed to improve our lives. The fact of the matter is, cybersecurity has become a huge issue (only to become more relevant as technology advances). My guest today, Dr. Eric Cole, has spent decades learning, understanding, and teaching people how to protect themselves and their loved ones from cyber-threats. Today, we talk about the apps that are more dangerous than others, how best to keep your children safe from online predators, what he calls, cyber-hygiene, why passwords are dead and what to do about it, and why social media will never fully protect children. SHOW HIGHLIGHTS 00:00 - Introduction   00:21 - Welcoming Dr. Eric Cole   00:26 - Importance of Cybersecurity for Families   01:24 - Dangers of Sharing Personal Information Online   02:47 - Targeting Vulnerable Individuals   04:26 - Impact of Technology on Parenting   05:45 - Prevalence of Child Exploitation   08:12 - Monitoring Kids' Online Interactions   10:00 - Social Media Security Measures   12:16 - Identifying Suspicious Accounts   15:00 - Limiting Kids' Access to Smartphones   19:09 - Balancing Technology Use   22:32 - Monitoring Social Media Comments   26:00 - Risks of Location Tracking in Photos   30:06 - Moving Beyond Passwords   32:31 - Avoiding Malicious Links   35:13 - Value of Online Protection Services   37:51 - Cell Phones and Privacy Concerns   43:03 - Importance of Software Updates   45:20 - Benefits of Using VPNs   46:43 - Upgrading Technology Safely   49:20 - AI as a Tool, Not a Replacement   52:43 - Practical Cybersecurity Tips   54:24 - Closing Remarks   Battle Planners: Pick yours up today! Order Ryan's new book, The Masculinity Manifesto. For more information on the Iron Council brotherhood. Want maximum health, wealth, relationships, and abundance in your life? Sign up for our free course, 30 Days to Battle Ready

Betreutes Fühlen
Impostor-Syndrom: das Gefühl, nichts zu können

Betreutes Fühlen

Play Episode Listen Later Jul 14, 2025 79:13


Ich kann nichts. Ich bin nichts wert. Wenn ich etwas schaffe, ist es nur Glück. Wann fliege ich auf? Wann merken die anderen, dass ich ein Hochstapler bin? Wie kann es sein, dass viele von uns trotz nachweisbarer Erfolge im Leben ständig befürchten, irgendwann aufzufliegen? Was das mit unserer Kindheit und struktureller Ungerechtigkeit zu tun hat, erfahrt ihr hier. Atze und Leon erklären in dieser Folge das Hochstapler-Syndrom, das eigentlich gar kein Syndrom ist. Fühlt euch gut betreut Leon & Atze Unsere bisherige Folge dazu: Hochgestapelt, tief gefallen (30. Juni 2020) Impostor: Wie fake bist du? | Terra Xplore mit Leon Windscheid & Lutz van der Horst https://www.youtube.com/watch?feature=shared&t=867&v=w2iqnFglAbg Bravata, D. M., Watts, S. A., Keefer, A. L., Madhusudhan, D. K., Taylor, K. T., Clark, D. M., ... & Hagg, H. K. (2020). Prevalence, predictors, and treatment of impostor syndrome: a systematic review. Journal of general internal medicine, 35, 1252-1275. DOI: 10.1007/s11606-019-05364-1 McElwee, R. O., & Yurak, T. J. (2010). The phenomenology of the impostor phenomenon. Individual Differences Research, 8(3), 184-197. Clance, P. R., & Imes, S. A. (1978). The imposter phenomenon in high achieving women: Dynamics and therapeutic intervention. Psychotherapy: Theory, Research & Practice, 15(3), 241–247. https://doi.org/10.1037/h0086006 Leary, M. R., Patton, K. M., Orlando, A. E., & Wagoner Funk, W. (2000). The impostor phenomenon: Self‐perceptions, reflected appraisals, and interpersonal strategies. Journal of personality, 68(4), 725-756. https://doi.org/10.1111/1467-6494.00114 Sakulku, J. (2011). The impostor phenomenon. The Journal of Behavioral Science, 6(1), 75-97. https://doi.org/10.14456/ijbs.2011.6 Evans, D. (2022, 18. April). Viola Davis on Hollywood: ‘You either have to be a Black version of a white ideal, or you have to be white'. The Guardian. Covington, M. V. (1984). The self-worth theory of achievement motivation: Findings and implications. The elementary school journal, 85(1), 5-20. https://www.journals.uchicago.edu/doi/epdf/10.1086/461388 Thompson, T., Davis, H., & Davidson, J. (1998). Attributional and affective responses of impostors to academic success and failure outcomes. Personality and Individual differences, 25(2), 381-396. https://doi.org/10.1016/S0191-8869(98)00065-8 Tumminia, A. M. (2023). When Feeling Like a Fake Takes a Toll on your Work: Examining the Moderating Effect of Task Characteristics on the Relationship Between Impostorism and the Use of Dysfunctional Work Strategies (Doctoral dissertation, City University of New York). Clance, P. R. (1985). Clance impostor phenomenon scale. Personality and Individual Differences. https://doi.org/10.1037/t11274-000 Clance, P. R. The Impostor Test and scoring [PDF]. Pauline Rose Clance. Abgerufen am 10. Juli 2025 von https://www.paulineroseclance.com/pdf/IPTestandscoring.pdf Clance, P. R. Impostor Phenomenon. Pauline Rose Clance. Abgerufen am 10. Juli 2025 von https://www.paulineroseclance.com/impostor_phenomenon.html Price, P. C., Holcomb, B., & Payne, M. B. (2024). Gender differences in impostor phenomenon: A meta-analytic review. Current Research in Behavioral Sciences, 100155. https://doi.org/10.1016/j.crbeha.2024.100155 Romano, N. (2016, 4. August). Viola Davis remembers her early childhood on a former plantation. Entertainment Weekly. https://web.archive.org/web/20181125204332/https://ew.com/article/2016/08/04/viola-davis-childhood-home-former-plantation/ Feenstra, S., Begeny, C. T., Ryan, M. K., Rink, F. A., Stoker, J. I., & Jordan, J. (2020). Contextualizing the impostor “syndrome”. Frontiers in psychology, 11, 575024. https://doi.org/10.3389/fpsyg.2020.575024

RNZ: Nine To Noon
The prevalence of multiple sclerosis has risen sharply

RNZ: Nine To Noon

Play Episode Listen Later Jul 13, 2025 9:36


A new study has found the prevalence of multiple sclerosis rose by a third between 2006 and 2022. 

DJStrickland Podcast
The Dark reality and effects of pornography on a generation with Melinda Tankard Reist

DJStrickland Podcast

Play Episode Listen Later Jul 11, 2025 58:42


Melinda Tankard Reist is an author, speaker, media commentator, blogger and advocate for women and girls. She is best known for her work addressing sexualisation, objectification, harms of pornography, sexual exploitation, trafficking and violence against women.SummaryIn this conversation, Danielle Strickland and her co-host James Sholl engage with Melinda Tankard Reist, a passionate advocate against the exploitation of women and children through pornography. They discuss the alarming rise of harmful sexual behaviors among youth, the cultural attitudes that normalize pornography, and the role of technology in perpetuating exploitation. Melinda shares insights from her research and experiences, highlighting the urgent need for collective action to combat these issues. The conversation emphasizes the importance of empathy, awareness, and advocacy in creating a safer world for women and girls.Takeaways* Melinda Tankard Reist is a passionate advocate against pornography and exploitation.* The rise of harmful sexual behaviors among youth is alarming and needs urgent attention.* Cultural attitudes often normalize pornography, making it difficult to combat its effects.* Technology plays a significant role in perpetuating exploitation and harmful behaviors.* Empathy is crucial in understanding the impact of pornography on individuals and society.Collective action is necessary to address the systemic issues surrounding pornography.* There is hope for change, as many individuals are beginning to recognize the harms of pornography.* Education and awareness are key in fighting against the normalization of pornography.* The fight against exploitation requires both personal and political action.* We must not be naive about the dangers posed by the pornography industry.Sound bites"We need a global ban on AI deep fake.""We are losing empathy and this is my biggest fear.""We deserve more than porn. We deserve to be loved."Important LinksFor parents: What you need to know: https://culturereframed.orgDiscussing with kids: https://parents.thorn.org/situation/Parental online controls: https://www.bark.usFighting Back: Fight The New Drug: https://fightthenewdrug.orgResisting porn: https://resistporn.orgREADING LIST 'Behind the Classroom Door', MTR, Eureka Street ,https://melindatankardreist.com/2025/05/behind-the-classroom-door-sexual-harassment-is-becoming-routine/‘P*rn's grooming starts young', MTR, Eureka Street https://melindatankardreist.com/2023/07/prns-grooming-starts-young-mtr-eureka-street-essay/“It makes my skin crawl”: sexual moaning rise in schools', MTR, https://melindatankardreist.com/2022/06/it-makes-my-skin-crawl-sexual-moaning-rise-in-schools/'Secondary Schools and a duty of care to keep students safe from harmful sexual behaviours', 'Off The Cuff' podcast, Kelly Humphries with guests Melinda Tankard Reist and Maha Melhem: https://kellyhumphries.com/podcast_episodes/maha-melhem-melinda-tankard-reist-the-complex-storm-harmful-sexual-behaviours-prn/'Digital Dangers: AI Weaponization and Online Exploitation', 'Off the Cuff' podcast, Kelly Humphries with guests Melinda Tankard Reist and Maha Melhem: https://kellyhumphries.com/podcast_episodes/digital-dangers-ai-weaponization-and-online-exploitation/Digital Dangers: AI Weaponization and Online Exploitation | Kelly HumphriesAI weaponization, sextortion, and the exploitation of young people are on the rise, creating a digital nightmare for vulnerable youth. Join me, along with Melinda Tankard Reist and Maha Melham, as we delve into this digitally dark world of online exploitation.kellyhumphries.com'Adolescence: It's time for Katie's story', MTR, MTR blog: https://melindatankardreist.com/2025/05/adolescence-its-time-for-katies-story/Never Again? Addressing Sexual Violence Must Include P*rnography', Melinda Tankard Reist, ABC Religion & Ethicshttps://www.abc.net.au/religion/never-again-addressing-sexual-violence-must-include-pornography/10094568‘Growing Up in P*rnland: Girls Have Had It with Porn Conditioned Boys, Melinda Tankard Reist, ABC Religion & Ethics,https://www.abc.net.au/religion/growing-up-in-pornland-girls-have-had-it-with-porn-conditioned-b/10097244‘In a society where male violence seems inevitable we need much more than education and awareness', Michael Salter, The Guardian, Tuesday April 30,2024 https://www.theguardian.com/commentisfree/2024/apr/30/in-a-society-where-male-violence-seems-inevitable-we-need-much-more-than-education-and-awareness‘Sexual violence is pushing girls out of school', UK Agenda Alliance https://www.agendaalliance.org/news/sexual-violence-absenteeism-girls-school/Children now ‘biggest perpetrators of sexual abuse against children'https://www.theguardian.com/society/2024/jan/10/children-now-biggest-perpetrators-of-sexual-abuse-against-children?utm_source=linkedin&utm_medium=social&utm_content=ap_qf09zbmvhm‘There are reports some students are making sexual moaning noises at school. Here's how parents and teachers can respond', Daryl Higgins, Gabrielle Hunt, The Conversation, January 31, 2024 https://theconversation.com/there-are-reports-some-students-are-making-sexual-moaning-noises-at-school-heres-how-parents-and-teachers-can-respond-220136‘Child sexual abuse by different classes and types of perpetrator: Prevalence and trends from an Australian national survey', Ben Mathews et al, Child Abuse & Neglect, Vol 147, January 2024, 106562https://www.sciencedirect.com/science/article/pii/S0145213423005501?via%3DihubOur Watch P*rnography, young people and preventing violence against women https://media-cdn.ourwatch.org.au/wp-content/uploads/sites/2/2020/11/20022415/Pornography-young-people-preventing-violence.pdfNational Plan to Address Violence Against Women https://www.dss.gov.au/ending-violence#:~:text=The%20National%20Plan%20outlines%20what,stop%20it%20before%20it%20starts.Chapters00:00 Introduction to the Conversation02:15 The Dark Reality of Pornography10:49 The Impact of Pornography on Youth16:58 Cultural Attitudes Towards Pornography23:00 The Role of Technology in Exploitation32:14 The Fight Against Exploitation42:45 Hope and Change in the Fight Against Pornography Get full access to Right Side Up: Danielle Strickland at daniellestrickland.substack.com/subscribe

It’s All Your Fault: High Conflict People
Child Abuse Allegations: Finding Truth and Safety in Family Court with Dr. Wendy Bourg

It’s All Your Fault: High Conflict People

Play Episode Listen Later Jul 10, 2025 53:00


Child Sexual Abuse Allegations in Family Court: Expert Insights with Dr. Wendy BourgIn this compelling episode, Bill Eddy and Megan Hunter welcome clinical psychologist Dr. Wendy Bourg for a rare and candid discussion about one of family court's most challenging issues. With decades of experience developing forensic interview guidelines and working directly with families, Dr. Bourg shares invaluable insights about navigating these complex situations.The conversation explores how courts, professionals, and families can move beyond emotional reactions to find practical solutions that prioritize child wellbeing. Dr. Bourg challenges common assumptions and offers fresh perspectives on handling these sensitive cases, drawing from her extensive work in Oregon's family court system.Questions Explored in This EpisodeWhat makes these cases particularly challenging for family courts?How can professionals avoid common pitfalls when investigating allegations?What approaches best serve children caught in these situations?Where do well-meaning professionals sometimes go wrong?How can courts balance competing priorities in unclear cases?Key Reasons to ListenGain practical insights from a leading expert in the fieldLearn about surprising research findings that challenge conventional wisdomUnderstand how to avoid common mistakes that can harm familiesDiscover innovative approaches to handling complex casesHear real-world examples that illuminate better ways forwardWhether you're a family court professional, mental health practitioner, or concerned parent, this episode offers crucial insights for anyone seeking to better understand and address these challenging situations. Join us for this important conversation that goes beyond typical discussions to explore practical, balanced approaches that put children first.Additional ResourcesGuest, Dr. Wendy Bourghttps://drwendybourg.com/Expert PublicationsEvaluating Sexual Abuse Reports In Family Court by Dr. Wendy BourgTell Me What Happened: Questioning Children About Abuse by Michael LambJeopardy in the Courtroom: A Scientific Analysis of Children's Testimony by Stephen CeciProfessional & Personal DevelopmentConflictInfluencer.com (website for individuals dealing with high-conflict in personal life)New Ways for Families® Training: For family and divorce professionalsConnect With UsVisit High Conflict Institute: highconflictinstitute.comSubmit questions for Bill and MeganBrowse our complete collection of books and resources in our online store—available in print and e-book formatsFind these show notes and all past episode notes on our websiteImportant NoticeOur discussions focus on behavioral patterns rather than diagnoses. For specific legal or therapeutic guidance, please consult qualified professionals in your area. (00:00) - Welcome to It's All Your Fault (01:31) - Child Sexual Abuse Allegations in Family Court (02:02) - Meet Dr. Wendy Bourg (03:19) - Her Interest in This Work (07:45) - Karpman Drama Triangle (09:35) - Prevalence (13:42) - True or Not True? (18:20) - Safety First and Hippocratic Oath (23:55) - Grey Area Solutions (24:42) - Increase in Frequency? (30:24) - Cycles of Hysteria (33:10) - Therapists and Forensic Truths (36:26) - Flaws Still in the System (37:36) - Working to Help Parents Come Around (39:07) - Percent of Cases That Are True (42:32) - Best Practice Tips (45:38) - No Common Trigger Points (47:10) - Thoughts for Judges (49:19) - Non-Family Members (50:39) - Wrap Up (51:55) - Reminders Learn more about our New Ways for Work Coaching sessions. Get started today!

Mold Talks with Michael Rubino
NBS #95: What It's Really Like to Remediate Mold: A Step-by-Step Client Recap

Mold Talks with Michael Rubino

Play Episode Listen Later Jul 7, 2025 63:13


What does it actually look like to go through a mold remediation—start to finish? In this episode of Never Been Sicker, Michael sits down with Kathleen LeGrys, a HomeCleanse client, to share her firsthand experience navigating chronic illness, discovering hidden mold in her home, and going through the full inspection and remediation process with HomeCleanse.After struggling for years with Lyme, Bartonella, and Myasthenia Gravis, Kathleen was still not improving as expected. Eventually, high mycotoxin levels led her functional medicine doctor to suspect mold exposure—and that kicked off a journey most people never expect to take.Kathleen walks us through:- The early overwhelm of discovering mold and deciding where to start- Why she chose to remediate her home in phases (and how she budgeted for it)- What she did before remediation to reduce exposure (including air purifiers and open windows)- How her lab markers improved just from lowering dust and airborne toxins- What she replaced in her home—and how she tested items like bedding and furniture to decide what to toss- The emotional, physical, and financial toll of the process—and why she has zero regretsIf you've ever felt overwhelmed by mold, toxins, or chronic symptoms—this is a must-listen success story.00:00 Introduction to Mold and Health Challenges02:50 Kathleen's Journey with Mold and Health06:00 Testing for Mold: Dust Tests vs. Mold Dogs09:11 Understanding Mycotoxins and Health Correlation11:45 The Cost of Mold Inspection and Remediation14:50 Mental Challenges in Addressing Mold Issues17:54 The Remediation Process: Logistics and Challenges21:08 Post-Remediation: Rebuilding and Testing23:58 Living with Mold: Interim Solutions27:06 The Importance of Replacing Contaminated Items30:00 Addressing Misconceptions About Mold33:56 Historical Perspectives on Mold Remediation35:51 Insurance Challenges and Mold Coverage37:32 Societal Perceptions of Mold and Health39:58 Understanding Mold Exposure and Symptoms46:12 The Prevalence of Mold in Homes49:57 Personal Experiences with Mold Remediation54:46 Advice for Those Facing Mold Issues

Break The Chain Podcast
#47 - Ketamine Education Services with Founder Finlay Worthington

Break The Chain Podcast

Play Episode Listen Later Jul 6, 2025 66:46


In this episode, Finley Worthington shares his personal journey through ketamine addiction, detailing the struggles he faced and the eventual decision to seek help. He discusses the stigma surrounding ketamine, the unique challenges it presents in rehab, and the importance of community support. Finley emphasises the need for education about ketamine addiction, particularly among young people, and highlights the work of Ketamine Education Services in providing support and resources for those affected by addiction. The conversation also touches on the broader societal issues contributing to addiction and the importance of connection and honesty in recovery.You can find Ketamine Education Services athttps://www.facebook.com/ketamineeducationserviceshttps://www.instagram.com/ketamine_education_services/Chapters00:00: Finley's Journey into Addiction10:43: The Impact of Ketamine on Life15:58: Turning Point: Seeking Help and Recovery19:27: Creating Community and Support for Recovery24:33: Challenges of Ketamine Addiction and Recovery32:17: Future of Ketamine Addiction Treatment37:40: Understanding the Detox Pathway40:36: Recognising Warning Signs of Ketamine Use43:21: The Importance of Addressing Underlying Issues46:11: The Prevalence of Ketamine Addiction50:40: The Impact of Trauma on Addiction54:07: Self-Medication and Mental Health Challenges58:33: Establishing Ketamine Education Services01:06:19: Advice for Those Struggling with Addiction

The Future of Everything presented by Stanford Engineering

Psychiatrist Carolyn Rodriguez studies hoarding disorder and says that all of us have attachments to our possessions. But for many, these attachments can disrupt daily life and even pose health risks. For those with loved ones who struggle with hoarding disorder, she says treatments exist, including cognitive behavioral therapy (CBT). Lately, she's been studying how virtual reality can augment CBT through virtual discarding practice and ways brain stimulation may improve symptoms. But, Rodriguez says, never underestimate the value of empathy for those in need of help, as she tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Carolyn RodriguezConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces Carolyn Rodriguez, a professor of psychiatry and behavioral science at Stanford University.(00:02:47) Motivation to Study Hoarding DisorderWhy Carolyn chose to focus her research on hoarding disorder.(00:03:44) Collecting Versus HoardingDistinguishing between normal behavior and clinically significant hoarding.(00:05:47) Prevalence of Hoarding DisorderThe universality and pervasiveness of hoarding disorder.(00:07:11) The Brain Science Behind HoardingEarly neuroscience findings on attachment and discarding behavior.(00:08:47) Dopamine and Excessive AcquisitionThe connection between hoarding and potential dopamine reward pathways.(00:09:55) Risk Factors and Cognitive ChallengesPersonality traits, genetics, and processing difficulties involved in hoarding.(00:11:14) Gender Differences and Insight IssuesGender prevalence in treatment-seeking and the concept of anosognosia.(00:12:35) The “Why” Behind HoardingHow motivations and emotional attachments influence behavior.(00:13:50) Onset and Progression of DisorderTypical onset age, aging effects, and early warning signs.(00:15:05) Historical References to HoardingAccounts from ancient literature of hoarding-like behavior(00:17:16) Attachment to ObjectsThe emotional, aesthetic, and identity-based reasons people retain objects.(00:20:45) Current Treatment OptionsThe treatment landscape, including lack of medications and focus on CBT.(00:22:30) Chronic Nature of Hoarding DisorderFraming hoarding as a long-term condition with hopeful outcomes.(00:23:08) Virtual Reality for TreatmentA study on using VR to safely practice letting go of personal items.(00:25:58) Neuromodulation ResearchUsing non-invasive brain stimulation to reduce acquisition urges.(00:27:00) Advice for Individuals and FamiliesThe importance of empathy and self-care for individuals and caregivers.(00:28:47) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

Christian Podcast Community
Pursuing Purity with Gospel Hope | Zach Sparkman | LLFT Series

Christian Podcast Community

Play Episode Listen Later Jul 3, 2025 28:08


In this episode of the Shepherd Press Podcast, author Zach Sparkman discusses the prevalent struggle with pornography, particularly among teens. Drawing from his Lifeline for Teens mini-book, 'Help! I Want to Stay Pure', Sparkman provides both statistical insights and practical advice on combating sexual immorality through a biblical lens. The discussion covers the physiological impact of pornography, helpful principles drawn from King David's fall into sin, and the acronym ARISE, which offers a structured approach to resisting temptation. The episode concludes with guidance for parents on how to address their teen's struggle with pornography.00:23 Pornography and Its Impact on Teens01:43 The Prevalence and Dangers of Pornography02:34 Understanding the Temptation and Its Effects09:26 Differentiating Temptation from Sin14:21 David and Bathsheba: Lessons on Temptation16:39 The ARISE Acronym for Fighting Temptation22:03 Practical Steps and Hope for Teens24:33 Advice for Parents26:47 Conclusion and Final ThoughtsGrab a copy of our mini-book: 'Help! I Want to Stay Pure' Check Out our LifeLine for Teens Mini-book SeriesFollow Us on InstagramFollow Us on Facebook

JACC Speciality Journals
Brief Introduction - Prevalence and Mortality of Cardiovascular-Kidney-Metabolic Syndrome in China: A Nationwide Population-Based Study | JACC: Asia

JACC Speciality Journals

Play Episode Listen Later Jul 1, 2025 1:37


JACC Speciality Journals
Prevalence and Mortality of Cardiovascular-Kidney-Metabolic Syndrome in China: A Nationwide Population-Based Study | JACC: Asia

JACC Speciality Journals

Play Episode Listen Later Jul 1, 2025 2:49


Rheumnow Podcast
PCR- Prevalence, Cost, & Risk (6.27.2025)

Rheumnow Podcast

Play Episode Listen Later Jun 27, 2025 21:47


Dr. Jack Cush reviews the news and journal reports from last week on RheumNow.com

Run The Numbers
Inside the CFO Tech Stack (and the Failure Museum): Insights From Norwest's Sean Jacobsohn

Run The Numbers

Play Episode Listen Later Jun 26, 2025 48:00


The CFO software ecosystem is highly fragmented and ripe for disruption. Sean Jacobsohn, partner at Norwest, has a front-row seat to the action: He's backed 10 companies selling to CFOs, while Norwest has invested in 20. Having identified 300 companies in 15 different categories operating in the space, he joins CJ to share takeaways from his market map of the evolving CFO software stack. They dig into what's driving disruption, how new players are challenging legacy systems, and what it takes for founders to stand out. The conversation spans everything from the staying power of spreadsheets to the debate between building for verticals versus horizontals, the future of FP&A, and how AI agents might reshape the stack. Sean delves into the dynamics of partnerships, outlining five key rules for successful collaborations. Additionally, he talks about his Failure Museum which showcases a collection of items representing failed products and companies, and breaks down what he has identified as the six forces of failure.—LINKS:Sean Jacobsohn on LinkedIn: https://www.linkedin.com/in/seanjacobsohnNorwest: https://www.nvp.comMarket Map: Reimagining the CFO Software Stack: https://www.nvp.com/blog/market-map-reimagining-cfo-software-stackFailure Museum: https://failure.museum/CJ on X (@cjgustafson222): https://x.com/cjgustafson222Mostly metrics: http://mostlymetrics.comRELATED EPISODES:CFO of FloQast on Why Finance Teams are Data Curators: The $7 Million Wake-Up Call: Mastering Rebates for Profitability with Enable's Nick Rose: G2 CFO Chad Gold on Building A Durable Career as a Venture Backed Exec: —TIMESTAMPS:(00:00) Preview and Intro(02:04) Sponsor – Rippling Spend | Pulley | Navan(06:08) The Fragmentation of the CFO Tool Ecosystem(07:24) Advice for Founders on Deep Domain Expertise(10:39) Enable: Disrupting an Existing Solution Versus Creating a New Category(12:32) The Prevalence of Spreadsheets in the Current Ecosystem(13:39) Solutions Built for Verticals Versus Horizontals(16:24) Sponsor – NetSuite | Planful | Tabs(20:22) Vertical Software and the Move to the Cloud(22:17) The Likelihood of Consolidation by Incumbents in the Space(24:53) Developments in the FP&A Space(26:55) The Future of AI Agents in Finance(28:05) The Five Key Rules of Partnerships: Partner Fit(29:17) Entering New Markets(30:16) Enablement: The Importance of Training(32:28) Reciprocation(33:49) How Often the Little Guy Approaches the Big Guy in Partnerships(34:51) M&A in Partnerships(37:01) The Best Way To Form a Partnership(37:45) The Inspiration Behind the Failure Museum(39:14) The Six Forces of Failure(40:38) Falling out of Product-Market Fit(41:25 Examples of Failures From the Failure Museum(44:58) How the Failure Museum Informs Sean's Work at Norwest(46:12) The Magic of Pivoting—SPONSORS:Rippling Spend is a spend management software that gives you complete visibility and automated policy controls across every type of spend, saving you time and money. Get a demo to see how much time your org would save at rippling.com/metrics.Pulley is the cap table management platform built for CFOs and finance leaders who need reliable, audit-ready data and intuitive workflows, without the hidden fees or unreliable support. Switch in as little as 5 days and get 25% off your first year: pulley.com/mostlymetrics.Navan is the all-in-one travel and expense solution that helps finance teams streamline reconciliation, enforce policies automatically, and gain real-time visibility. It connects to your existing cards and makes closing the books faster and smarter. Visit navan.com/Runthenumbers for your demo.NetSuite is an AI-powered business management suite, encompassing ERP/Financials, CRM, and ecommerce for more than 41,000 customers. If you're looking for an ERP, head to https://netsuite.com/metrics and get the CFO's Guide to AI and Machine Learning.Planful's financial planning software can transform your FP&A function. Built for speed, accuracy, and confidence, you'll be planning your way to success and have time left over to actually put it to work. Find out more at www.planful.com/metrics.Tabs is a platform that brings all of your revenue-facing data and workflows - billing, AR, payments, rev rec, and reporting - onto a single system so you can automate and be more flexible. Find out more at: tabs.inc/metrics.#CFOsoftware #marketmap #verticalSaaS #FPandA #FailureMuseum Get full access to Mostly metrics at www.mostlymetrics.com/subscribe

Backchat
Obesity prevalence report / Silver economy development / IPO performance

Backchat

Play Episode Listen Later Jun 26, 2025 55:00


🧠 Let's Talk Brain Health!
How to Start the Brain Health Conversation with Your Provider: Insights from a Board-Certified Neurologist, Dr. Jonathan Artz, MD

🧠 Let's Talk Brain Health!

Play Episode Listen Later Jun 25, 2025 56:32


In this episode of the Let's Talk Brain Health! Podcast, co-host Dr. Jonathan Artz, MD, an experienced neurologist, shares his extensive background and insights on cognitive health. Dr. Artz discusses his journey from medical school through various specializations, ultimately focusing on cognitive disorders and dementia. He emphasizes the importance of early conversations about brain health, lifestyle modifications, and the role of primary care providers in initial evaluations. Dr. Artz also outlines key factors affecting brain health, the limitations of current medications, and common misconceptions about cognitive diseases. Listeners are encouraged to engage in preventive measures actively and have detailed discussions with healthcare providers about any cognitive concerns.**Recorded live on March 10, 2025, during our Brain Week 2025 events and adapted to this podcast episode.**00:00 Welcome and Introduction to Dr. Jonathan Artz00:37 Dr. Arts' Educational and Professional Journey02:01 Establishing a Cognitive Program at Kaiser Permanente02:45 Transition to Renown Institute of Neurosciences04:06 Common Questions About Brain Health04:24 The Role of Primary Care in Cognitive Health06:48 Key Information to Share with Healthcare Providers13:53 Importance of Sleep and Other Factors16:27 When to Start the Conversation About Cognitive Health22:42 Red Flags and Immediate Actions for Brain Health26:26 The Prevalence of Brain Health Supplements27:01 Importance of Disclosing Supplements to Healthcare Providers28:26 Common Cognitive Concerns and Symptoms28:46 The Significance of Memory and Learning Issues29:21 Understanding Speech and Language Problems29:32 When to Seek Medical Attention for Cognitive Issues32:43 The Role of Neurologists in Cognitive Health33:14 The Importance of Patient History in Neurology33:45 Encouraging Open Communication with Healthcare Providers35:31 Practical Tips for Cognitive Wellbeing35:53 The Impact of Lifestyle on Brain Health41:50 The Role of Social Interaction in Cognitive Health42:52 The Risks of Smoking and Other Substances48:34 The Complexity of Diagnosing Dementia51:31 Current Treatments and Their Limitations56:52 The Importance of Lifestyle in Managing Cognitive Health57:25 Conclusion and Encouragement to Start the Conversation"Twelve Questions to Ask Your Doctor For Better Brain Health" Conversation Starters from the American Academy of Neurology Explore additional podcast conversations in our library of 30-minute conversations with the experts on a wide variety of topics, from nutrition to oral health

JACC Speciality Journals
Prevalence and Correlates of Lipoprotein(a) Testing in a Diverse Cohort of U.S. Adults | JACC: Advances

JACC Speciality Journals

Play Episode Listen Later Jun 25, 2025 2:30


Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Prevalence and Correlates of Lipoprotein(a) Testing in a Diverse Cohort of U.S. Adults.

JACC Speciality Journals
Trends in Prevalence, Treatment, and Relationship of Metabolic Syndrome and Individual Components by Race/Ethnicity, 1999-2018 | JACC: Advances

JACC Speciality Journals

Play Episode Listen Later Jun 25, 2025 2:44


Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Trends in Prevalence, Treatment, and Relationship of Metabolic Syndrome and Individual Components by Race/Ethnicity, 1999-2018.

JACC Speciality Journals
Mechanistic insights into reduced arrhythmia prevalence in female endurance athletes | JACC: Clinical Electrophysiology

JACC Speciality Journals

Play Episode Listen Later Jun 24, 2025 11:07


Dr. Emile Daoud, Deputy Editor of JACC Clinical Electrophysiology discusses mechanistic insights into reduced arrhythmia prevalence in female endurance athletes.

Real Talk: Eosinophilic Diseases
Bone Mineral Density in Pediatric Eosinophilic Esophagitis

Real Talk: Eosinophilic Diseases

Play Episode Listen Later Jun 24, 2025 33:16


Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Anna Henderson, MD, a pediatric gastroenterologist at Northern Light Health in Maine, about bone mineral density in EoE patients. They discuss a paper she co-authored on the subject. Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship that exists between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:50] Co-host Ryan Piansky introduces the episode, brought to you thanks to the support of Education Partners Bristol Myers Squibb, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz.   [1:17] Holly introduces today's topic, eosinophilic esophagitis (EoE), and bone density.   [1:22] Holly introduces today's guest, Dr. Anna Henderson, a pediatric gastroenterologist at Northern Light Health in Maine.   [1:29] During her pediatric and pediatric gastroenterology training at Cincinnati Children's Hospital, she took a special interest in eosinophilic esophagitis. In 2019, Dr. Henderson received APFED's NASPGHAN Outstanding EGID Abstract Award.   [1:45] Holly, a feeding therapist in Maine, has referred many patients to Dr. Henderson and is excited to have her on the show.   [2:29] Dr. Henderson is a wife and mother. She loves to swim and loves the outdoors. She practices general pediatric GI in Bangor, Maine, at a community-based academic center.   [2:52] Her patient population is the northern two-thirds of Maine. Dr. Henderson feels it is rewarding to bring her expertise from Cincinnati to a community that may not otherwise have access to specialized care.   [3:13] Dr. Henderson's interest in EoE grew as a GI fellow at Cincinnati Children's. Her research focused on biomarkers for disease response to dietary therapies and EoE's relationship to bone health.   [3:36] As a fellow, Dr. Henderson rotated through different specialized clinics. She saw there were many unanswered questions about the disease process, areas to improve treatment options, and quality of life for the patients suffering from these diseases.   [4:00] Dr. Henderson saw many patients going through endoscopies. She saw the social barriers for patients following strict diets. She saw a huge need in EoE and jumped on it.   [4:20] Ryan grew up with EoE. He remembers the struggles of constant scopes, different treatment options, and dietary therapy. Many people struggled to find what was best for them before there was a good approved treatment.   [4:38] As part of Ryan's journey, he learned he has osteoporosis. He was diagnosed at age 18 or 19. His DEXA scan had such a low Z-score that they thought the machine was broken. He was retested.   [5:12] Dr. Henderson explains that bone mineral density is a key measure of bone health and strength. Denser bones contain more minerals and are stronger. A low bone mineral density means weaker bones. Weaker bones increase the risk of fracture.   [5:36] DEXA scan stands for Dual Energy X-ray Absorptiometry scan. It's a type of X-ray that takes 10 to 30 minutes. A machine scans over their bones. Typically, we're most interested in the lumbar spine and hip bones.   [5:56] The results are standardized to the patient's height and weight, with 0 being the average. A negative number means weaker bones than average for that patient's height and weight. Anything positive means stronger bones for that patient's height and weight.   [6:34] A lot of things can affect a patient's bone mineral density: genetics, dietary history, calcium and Vitamin D intake, and medications, including steroid use. Prednisone is a big risk factor for bone disease.   [7:07] Other risk factors are medical and auto-immune conditions, like celiac disease, and age. Any patient will have their highest bone density in their 20s to 30s. Females typically have lower bone mineral density than males.   [7:26] The last factor is lifestyle. Patients who are more active and do weight-bearing exercises will have higher bone mineral density than patients who have more of a sedentary lifestyle.   [7:56] Ryan was told his bone mineral density issues were probably a side-effect of the long-term steroids he was on for his EoE. Ryan is now on benralizumab for eosinophilic asthma. He is off steroids.   [8:36] Dr. Henderson says the research is needed to find causes of bone mineral density loss besides glucocorticoids.   [8:45] EoE patients are on swallowed steroids, fluticasone, budesonide, etc. Other patients are on steroids for asthma, eczema, and allergic rhinitis. These may be intranasal steroids or topical steroids.   [9:01] Dr. Henderson says we wondered whether or not all of those steroids and those combined risks put the EoE population at risk for low bone mineral density. There's not a lot published in that area.   [9:14] We know that proton pump inhibitors can increase the risk of low bone mineral density. A lot of EoE patients are on proton pump inhibitors.   [9:23] That was where Dr. Henderson's interest started. She didn't have a great way to screen for bone mineral density issues or even know if it was a problem in her patients more than was expected in a typical patient population.   [9:57] Holly wasn't diagnosed with EoE until she was in her late 20s. She was undiagnosed but was given prednisone for her problems. Now she wonders if she should get a DEXA scan.   [10:15] Holly hopes the listeners will learn something and advocate for themselves or for their children.   [10:52] If a patient is concerned about their bone mineral density, talking to your PCP is a perfect place to start. They can discuss the risk factors and order a DEXA scan and interpret it, if needed.   [11:11] If osteoporosis is diagnosed, you should see an endocrinologist, specifically to discuss therapy, including medications called bisphosphonates.   [11:36] From an EoE perspective, patients can talk to their gastroenterologist about what bone mineral density risk factors may be and if multiple risk factors exist. Gastroenterologists are also more than capable of ordering DEXA scans and helping their patients along that journey.   [11:53] A DEXA scan is typically the way to measure bone mineral density. It's low radiation, it's easy, it's fast, and relatively inexpensive.   [12:10] It's also useful in following up over time in response to different interventions, whether or not that's stopping medications or starting medications.   [12:30] Dr. Henderson co-authored a paper in the Journal of Pediatric Gastroenterology and Nutrition, called “Prevalence and Predictors of Compromised Bone Mineral Density in Pediatric Eosinophilic Esophagitis.” The study looked at potential variables.   [12:59] The researchers were looking at chronic systemic steroid use. They thought it was an issue in their patients, especially patients with multiple atopic diseases like asthma, eczema, and allergic rhinitis. That's where the study started.   [13:22] Over the years, proton pump inhibitors have become more ubiquitous, and more research has come out. The study tried to find out if this was an issue or not. There weren't any guidelines for following these patients, as it was a retrospective study.    [13:42] At the time, Dr. Henderson was at a large institution with a huge EoE population. She saw that she could do a study and gather a lot of information on a large population of patients. Studies like this are the start of figuring out the guidelines for the future.   [14:34] Dr. Henderson wanted to determine whether pediatric patients with EoE had a lower-than-expected bone mineral density, compared to their peers. [14:44] Then, if there were deficits, she wanted to determine where they were more pronounced. Were they more pronounced in certain subgroups of patients with EoE?   [14:59] Were they patients with an elemental diet? Patients with an elimination diet? Were they patients on steroids or PPIs? Were they patients with multiple atopic diseases? Is low bone mineral density just a manifestation of their disease processes?   [15:14] Do patients with active EoE have a greater propensity to have low bone mineral density? The study was diving into see what the potential risk factors are for this patient population.   [15:45] The study was a retrospective chart review. They looked at patients aged 3 to 21. You can't do a DEXA scan on a younger patient, and 21 is when people leave pediatrics.   [16:03] These were all patients who had the diagnosis of EoE and were seen at Cincinnati Children's in the period between 2014 and 2017. That period enabled full ability for chart review. Then they looked at the patients who had DEXA scans.   [16:20] They did a manual chart review of all of the patients and tried to tease out what the potential exposures were. They looked at demographics, age, sex, the age of the diagnosis of EoE, medications used, such as PPIs, and all different swallowed steroids.   [16:44] They got as complete a dietary history as they could: whether or not patients were on an elemental diet, whether that was a full elemental diet, whether they were on a five-food, six-food, or cow's milk elimination diet.   [16:58] They teased out as much as they could. One of the limitations of a retrospective chart review is that you can't get some of the details, compared to doing a prospective study. For example, they couldn't tease out the dosing or length of therapy, as they would have liked.   [17:19] They classified those exposures as whether or not the patient was ever exposed to those medications, whether or not they were taking them at the time of the DEXA scan, or if they had been exposed within the year before the DEXA scan.   [17:40] They also looked at whether the patients had other comorbid atopic disorders, to see if those played a role, as well.   [18:03] The study found that there was a slightly lower-than-expected bone mineral density in the patients. The score was -0.55, lower than average but not diagnostic of a low bone mineral density, which would be -2 or below.   [18:27] There were 23 patients with low bone mineral density scores of -2 or below. That was 8.6% of the study patients. Typically, only 2.5% of the population would have that score. It was hard to tease out the specific risk factors in a small population of 23.   [18:57] They looked at what the specific risk factors were that were associated with low bone mineral density, or bone mineral density in general.   [19:12] After moving from Colorado, Holly has transferred to a new care team, and doctors wanted her baseline Vitamin D and Calcium levels. No one had ever tested that on her before. Dr. Henderson says it's hard because there's nothing published on what to do.   [19:58] The biggest surprise in the study was that swallowed steroids, or even combined steroid exposure, didn't have any effect on bone mineral density. That was reassuring, in light of what is known about glucocorticoid use.   [20:16] The impact of PPI use was interesting. The study found that any lifetime use of PPIs did seem to decrease bone mineral density. It was difficult to tease out the dosing and the time that a patient was on PPIs.   [20:34] Dr. Henderson thinks that any lifetime use of PPIs is more of a representation of their cumulative use of PPIs. At the time of the study, from 2014 to 2017, PPIs were still very much first-line therapy for EoE; 97% of the study patients had taken PPIs at some time.   [21:02] There are so many more options now for therapy when a patient has a new diagnosis of EoE, especially with dupilumab now being an option.   [21:11] Dr. Henderson speaks of patients who started on PPIs and have stayed on them for years. This study allows her to question whether we need to continue patients on PPIs. When do we discuss weaning patients off PPIs, if appropriate?   [22:05] Ryan says these podcasts are a great opportunity for the community at large and also for the hosts. He just wrote himself a note to ask his endocrinologist about coming off PPIs.   [22:43] Dr. Henderson says that glucocorticoid use is a known risk factor for low bone mineral density and osteoporosis. In the asthma population, inhaled steroids can slightly decrease someone's growth potential while the patient is taking them.   [23:10] From those two facts, it was thought that swallowed steroids would have a similar effect. But since they're swallowed and not systemic, maybe things are different.   [23:23] It was reassuring to Dr. Henderson that what her study found was that the swallowed steroid didn't affect bone mineral density. There was one other study that found that swallowed steroids for EoE did not affect someone's height.   [23:51] Dr. Henderson clarifies that glucocorticoids include systemic steroids like prednisone and hydrocortisone.     [23:57] Based on Dr. Henderson's retrospective study, fluticasone as a swallowed steroid did not affect bone mineral density. It was hard to tease out the dosing, but the cumulative use did not seem to result in a deficit for bone mineral density.   [24:16] Holly shared that when she tells a family of a child she works with that the child's gastroenterologist will likely recommend steroids, she will now give them the two papers Dr. Henderson mentioned. There are different types of steroids. The average person doesn't know the difference.   [25:15] Dr. Henderson thinks that for patients who have multiple risk factors for low bone mineral density, it is reasonable to have a conversation about bone health with their gastroenterologist to see whether or not a DEXA scan would be worth it.   [25:56] If low bone mineral density is found, that needs to be followed up on.   [26:03] There are no great guidelines, but this study is a good start on what these potential risk factors are. We need some more prospective studies to look at these risk factors in more detail than Dr. Henderson's team teased out in this retrospective study.   [26:23] Dr. Henderson tells how important it is for patients to participate in prospective longitudinal studies for developing future guidelines.   [26:34] Holly points out that a lot of patients are on restrictive diets. It's important to think about the whole picture if you are starting a medication or an elimination, or a restricted diet. You have to think about the impact on your body, overall.   [27:11] People don't think of dietary therapy as medication, but it has risks and benefits involved, like a medication.   [27:50] Dr. Henderson says, in general, lifestyle management is the best strategy for managing bone health. Stay as active as you can with weight-bearing exercises and eating a well-balanced diet. If you are on a restrictive diet, make sure it's well-balanced.   [28:12] Dr. Henderson says a lot of our patients have feeding disorders, so they see feeding specialists like Holly. A balanced diet is hard when kids are very selective in their eating habits.   [29:10] Dr. Henderson says calcium and Vitamin D are the first steps in how we treat patients with low bone mineral density. A patient who is struggling with osteoporosis needs to discuss it with their endocrinologist for medications beyond supplementation.   [29:31] Ryan reminds listeners who are patients always to consult with their medical team. Don't go changing anything up just because of what we're talking about here. Ask your care team some good questions.   [29:47] Dr. Henderson would like families to be aware, first, that some patients with EoE will have bone mineral density loss, especially if they are on PPIs and restrictive diets. They should start having those discussions with their providers.   [30:04] Second, Dr. Henderson would like families to be reassured that swallowed steroids and combined steroid exposure didn't have an impact on bone mineral density. Everyone can take that away from today's chat.   [30:18] Lastly, Dr. Henderson gives another plug for patient participation in prospective studies, if they're presented with the opportunity. It's super important to be able to gather more information and make guidelines better for our patients. [30:35] Holly thanks Dr. Henderson for coming on Real Talk — Eosinophilic Diseases and sharing her insights on bone mineral density, and supporting patients in Maine.   [30:57] Dr. Henderson will continue to focus on the clinical side. She loves doing outreach clinics in rural Maine. It's rewarding, getting to meet all of these patients and taking care of patients who would otherwise have to travel hours to see a provider.   [32:01] Ryan thinks the listeners got a lot out of this. For our listeners who would like to learn more about eosinophilic disorders, please visit APFED.org and check out the links in the show notes.   [32:11] If you're looking to find specialists who treat eosinophilic disorders, we encourage you to use APFED's Specialist Finder at APFED.org/specialist.   [32:19] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at APFED.org/connections.   [32:28] Ryan thanks Dr. Henderson for joining us today for this great conversation. Holly also thanks APFED's Education Partners Bristol Myers Squibb, Sanofi, Regeneron, and Takeda for supporting this episode.   Mentioned in This Episode: Anna Henderson, MD, a pediatric gastroenterologist at Northern Light Health in Maine Cincinnati Children's “Prevalence and Predictors of Compromised Bone Mineral Density in Pediatric Eosinophilic Esophagitis.” Journal of Pediatric Gastroenterology and Nutrition   APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections   Education Partners: This episode of APFED's podcast is brought to you thanks to the support of Bristol Myers Squibb, Sanofi, Regeneron, and Takeda.   Tweetables:   “DEXA scan stands for dual-energy X-ray absorptiometry scan. It's a type of X-ray where a patient lies down for 10 to 30 minutes. A machine scans over their bones. Typically, we're most interested in the lumbar spine and hip bones.” — Anna Henderson, MD   “We wondered whether or not all of those steroids and those combined risks even put our EoE population at risk for low bone mineral density. There's not a lot published in that area.” — Anna Henderson, MD   “If a patient is worried [about their bone mineral density], their PCP is a perfect place to start for that. They're more than capable of discussing the risk factors specific for that patient, ordering a DEXA scan, and interpreting it if need be.” — Anna Henderson, MD   “I think we need some more prospective studies to look at these risk factors in a little bit more detail than we were able to tease out in our retrospective review.” — Anna Henderson, MD   “Just another plug for the participation in prospective studies, if you're presented with the opportunity. It's super important to be able to gather more information and to be able to make guidelines better for our patients about these risks.” — Anna Henderson, MD

Business Scholarship Podcast
Ep.250 – Nicole Cade, Joshua Gunn & Alex Vandenberg on List Experiments and Earnings Manipulation

Business Scholarship Podcast

Play Episode Listen Later Jun 23, 2025 29:40


Nicole Cade, associate professor of business administration at the University of Pittsburgh; Joshua Gunn, associate professor of business administration at the University of Pittsburgh; and Alex Vandenberg, assistant professor of accountancy at the University of Illinois Urbana-Champaign, join the Business Scholarship Podcast to discuss their article Measuring the Prevalence of Earnings Manipulations: A Novel Approach. This episode is hosted by Andrew Jennings, associate professor of law at Emory University, and was edited by Brynn Radak, a recent law graduate at Emory University.

While you wait...
The Truth About Overactive Bladder Medications: Benefits, Risks, and Alternatives

While you wait...

Play Episode Listen Later Jun 23, 2025 12:37 Transcription Available


If you've ever been prescribed medication for overactive bladder, you might wonder what it's actually doing and what the risks are. In this episode, I break down the two main types of medications used to treat OAB: anticholinergics and beta-3 agonists. We'll talk about how they work, the side effects (including memory concerns), and how to weigh the benefits and risks. I also explore alternative options like Botox and nerve stimulation, and why shared decision-making with your provider matters more than ever. If bladder urgency or leaking has been part of your life, this episode will help you make informed, confident choices about your treatment path.For more information on this topic: https://journals.lww.com/fpmrs/abstract/2017/05000/augs_consensus_statement__association_of.4.aspx#:~:text=Given%20the%20available%20evidence%2C%20which,medications%20in%20patients%20at%20risk.https://pubmed.ncbi.nlm.nih.gov/34213600/Timeline00:30 Introduction to Overactive Bladder 00:48 Behavioral Treatments for Overactive Bladder 00:57 Medications for Overactive Bladder 01:18 Anticholinergic Medications and Memory Concerns 01:37 Types of Medications for Overactive Bladder 03:55 Studies on Anticholinergics and Cognitive Impairment 03:23 Clinical Guidelines and Recommendations 04:26 Prevalence and Types of Overactive Bladder 05:00 Side Effects and Risk Factors 05:38 Research Findings on Anticholinergics 08:32 Considerations for Prescribing Medications 10:38 Alternative Treatments and Final Thoughts

OPENPediatrics
Global PARITY Study: Pediatric Critical Illness Insights by T. Kortz, A. Holloway | OPENPediatrics

OPENPediatrics

Play Episode Listen Later Jun 23, 2025 44:32


This World Shared Practice Forum reviews the Global PARITY study, a comprehensive research initiative aimed at understanding and addressing pediatric critical illness in resource-constrained settings. The discussion highlights the methodology, challenges, and key findings of the study, emphasizing the high prevalence of critical illnesses such as pneumonia, sepsis, and malaria among children in low socio-demographic index regions. The authors stress the importance of basic critical care interventions and the need for global health equity, advocating for the integration of critical care into health systems worldwide. LEARNING OBJECTIVES - Understand the methodology and challenges of conducting the Global Parity Study in resource-constrained settings. - Identify the most common pediatric critical illnesses and their prevalence in low socio-economic regions. - Recognize the importance of basic critical care interventions in improving health outcomes for critically ill children. - Appreciate the role of global health equity and the need for integrating critical care into health systems. - Explore the potential impact of research findings on policy decisions and resource allocation in healthcare. AUTHORS Teresa Kortz, MD, MS, PhD Associate Professor of Clinical Pediatrics University of California, San Francisco Adrian Holloway, MD Associate Professor Pediatrics University of Maryland School of Medicine, Department of Pediatrics Traci Wolbrink, MD, MPH‌ Senior Associate in Critical Care Medicine Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital Associate Professor of Anesthesia Harvard Medical School DATE Initial publication date: June 23, 2025. ARTICLE REFERENCED Kortz TB, Holloway A, Agulnik A, et al. Prevalence, aetiology, and hospital outcomes of paediatric acute critical illness in resource-constrained settings (Global PARITY): a multicentre, international, point prevalence and prospective cohort study. Lancet Glob Health. 2025;13(2):e212-e221. doi:10.1016/S2214-109X(24)00450-9 TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/as/sf6v5frcmb9j5pt3vrrss67/Kortz__Holloway_PWSP_June_2025_Transcript Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access, thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu Please note: OPENPediatrics does not support or control any related videos in the sidebar; these are placed by YouTube. We apologize for any inconvenience this may cause. CITATION Kortz TB, Holloway A, Wolbrink TA. Global PARITY Study: Pediatric Critical Illness Insights. 06/2025. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/global-parity-study-pediatric-critical-illness-insights-by-t-kortz-a-holloway-openpediatrics.

The ShiftShapers Podcast
#517 Patient No More: Medical Harm, Misdiagnosis, and Taking Control with Helene M. Epstein

The ShiftShapers Podcast

Play Episode Listen Later Jun 17, 2025 28:38 Transcription Available


Why Are We Paying More for Worse Health? | ShiftShapersIn this episode of ShiftShapers, host David A. Saltzman welcomes Helene M. Epstein—writer, speaker, and patient advocate behind the Substack series Patient No More. Helene dives deep into America's epidemic of medical errors, misdiagnoses, and system failures. She breaks down why even the most advanced technology and training haven't improved patient safety, how profit-driven healthcare puts patients at risk, and—most importantly—what individuals can do to protect themselves and their families. From shocking statistics about misdiagnosis to the hidden realities of rural hospital closures, Helene provides practical advice and hope for patients who are ready to become their own advocates.

Academy i3 Podcast
Brain Health in Workforce Wellness ft. Maria Garay-Serratos

Academy i3 Podcast

Play Episode Listen Later Jun 10, 2025 44:45


Learn how chronic stress and traumatic brain injuries can silently impact workplace dynamics and employee wellbeing!In this episode of the Academy I3 podcast, hosts Charlie and Shane engage in a thought provoking discussion with Dr. Maria Garay Seratos, an expert in domestic violence, traumatic brain injury (TBI), and chronic traumatic encephalopathy (CTE). Dr. Seratos talked about the profound impact of brain injuries and chronic stress on groups that are marginalized, particularly within the context of child welfare and the workplace. She highlights the critical symptoms and long-term effects associated with TBI and chronic stress, underscoring the need for greater awareness and support in professional environments. Dr. Seratos emphasizes the importance of creating brain health initiatives, educating the workforce, and integrating these efforts into broader DEI strategies. This episode sheds light on a largely unrecognized issue, urging organizations to prioritize brain health as a fundamental component of employee wellbeing and organizational success.Episode Chapters:00:00 Meet Dr. Maria Garay Soratos02:11 The Link Between Brain Health and DEI Challenges04:09 Understanding Traumatic Brain Injury (TBI)06:04 Non-Concussive Head Impacts and CTE07:20 The Prevalence and Impact of TBI10:10 Brain Health and Chronic Stress11:28 Intersectionality and Brain Health in the Workplace14:39 Misconceptions About Brain Health19:53 Strategies for Supporting Brain Health in the Workplace35:32 The Role of Leadership in Promoting Brain Health39:37 Long-Term Benefits of Prioritizing Brain Health41:00 Envisioning the Future of DEI and Brain Health44:07 Conclusion and Final ThoughtsLearn about our guest: María E. Garay-Serratos, MSW, PhD, is a domestic violence – traumatic brain injury/chronic traumatic encephalopathy (DV-TBI/CTE) expert and thought leader. Her life's mission is to create global awareness to address the silent and unrecognized DV-TBI/CTE pandemic. Dr. Garay-Serratos is currently the Founder and CEO of Pánfila Domestic Violence HOPE Foundation and the Protagonist, Associate Producer, DV-TBI/CTE Expert Consultant for This Hits Home, a feature documentary released in 2023. Her work and story have also been the focus of various media/social media articles/interviews including NPR, The National Desk Spotlight on America, USC News, The Global Good Podcast, HuffPost, The Los Angeles Times, Boston University CTE Center, and Concussion Legacy Foundation. Prior to founding Pánfila and involvement with This Hits Home, Dr. Garay- Serratos served as a C-level executive for over 25 years for various non-profit organizations. She attended Pitzer College in Claremont, California, where she earned her undergraduate degree in sociology. Her graduate studies were in the Suzanne Dworak-Peck School of Social Work at the University of Southern California where she earned both a master's degree and a doctorate.Check out Dr. Garay-Serratos' organization: Pánfila Domestic Violence HOPE FoundationSubscribe for more workforce wellness content: https://www.youtube.com/@TheAcademySDSUFollow us on LinkedIn: linkedin.com/company/sdsuacademy#BrainHealth #WorkforceWellness #DEI

Rio Bravo qWeek
Episode 193: Gestational Diabetes Intro

Rio Bravo qWeek

Play Episode Listen Later Jun 6, 2025 24:04


Episode 193: Gestational Diabetes IntroJesica Mendoza (OMSIII) describes the pathophysiology of gestational diabetes and the right timing and method of screening for it. Dr. Arreaza adds insight into the need for culturally-appropriate foods, such as vegetables in Mexican cuisine.    Written by Jesica Mendoza, OMSIII, Western University of Health Sciences, College of Osteopathic Medicine of the Pacific. Editing by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.DefinitionGestational diabetes mellitus (GDM) is a condition that occurs to previously non-diabetic pregnant women, caused by glucose intolerance at around the 24th week of gestation. PathophysiologyGDM arises due to an underlying pancreatic beta cell dysfunction in the mother which leads to a decrease in the amount of insulin produced and thus leads to higher blood sugar levels during pregnancy. The placenta of the fetus will produce hPL (human placental lactogen) to ensure a steady supply of sugars to the fetus, creating an anti-insulin effect. However, hPL readily crosses the placental barrier causing the mothers insulin requirement to increase, when the mother's pancreas cannot increase production of insulin to that level needed to counter the effect of hPL they become diabetic, and this leads to gestational diabetes. So, basically the placenta is asking for more glucose for the baby and the mother's pancreas struggles to keep the glucose level within normal limits in the body of the mother. If left untreated, high levels of glucose in the mother can cause glucotoxicity in the mother.“Glucotoxicity” refers to the toxic effect of glucose. Glucose is the main fuel for cell functions, but when it is high in the bloodstream, it causes toxicity to organs. Prevalence of GDM.The CDC reports mean prevenance of GDM is 6.9%. In U.S. mothers the prevenance increased from 6.0% in 2016 to 8.3% in 2021. Many different factors have played a role in increasing gestational diabetes in American mothers, some of those being the ongoing obesity epidemic with excess body weight being a known risk factor for insulin resistance. Another being advanced maternal age (AMA) as more American women have children later in life their body becomes less sensitive to insulin and requires a higher insulin output on top of the insulin that is required for the fetus. The “American diet” is also something that has a big effect in diabetes development. With the increase of high-carb foods that are readily available, the diet of Americans has declined and is affecting the metabolic health of mothers as they carry and deliver their children. Despite ongoing awareness of GDM, 6% to 9% of pregnant women in the United States are diagnosed with gestational diabetes, and the prevalence continues to increase worldwide. It is estimated that in 2017 18.4 million pregnancies were affected by GDM in the world, which then continued to increase to 1 in 6 births to women with GDM in 2019. It was also found that women living in low-income communities were disproportionately affected due to limited healthcare access. Additionally, women with GDM had a 1.4-fold increase in likelihood of undergoing a c-section, with 15% increase in risk of requiring blood transfusion. Screening for GDMGestational diabetes is screened between the 24th to 28th week of gestation in all women without known pregestational diabetes. In women who have high-risk for GDM the screening occurs during the first trimester, these women usually have at least one of the following: BMI > 30, prior history of GDM, known impaired glucose metabolism, and/or a strong family history of diabetes. The screening during the first trimester is to detect “pregestational diabetes” because we have to keep a good glycemic control to improve outcomes of pregnancy. So, if it's positive, you start treatment immediately. If these women are found to have a normal glucose, they repeat the testing again as done normally, at 24-28 weeks of gestation. How do we screen?The screening itself consists of two types of approaches. The two-step approach includes a 50-gram oral glucose tolerance test (OGTT), where blood glucose is measured in an hour and if it is below 140 they are considered to not have GDM, however if the reading is greater than 140 they must then do a 3-hour, 100g oral glucose tolerance test. The 3-hour OGTT includes measuring the blood sugars at Fasting which should be less than 95, at 1 hour at less than 180, at 2 hours at less than 155, and at 3 hours at less than 140. If 2 or more of these values exceed the threshold the patient is diagnosed with gestational diabetes mellitus. The one-step approach includes 75g after an overnight fast. Blood glucose is measured while fasting which should be less than 92, at 1 hour less than 180 and at 2 hours less than 153. If any one of these values is exceeded, the patient is diagnosed with GDM.If the mother is found to be GDM positive during pregnancy she will also need continued screening post-partum to monitor for any development of overt diabetes. The testing is usually 75g 2-hour OGTT at 6-12 weeks postpartum. If this testing is normal, then they are tested using HbA1c every 3 years. If the post-partum testing shows pre-diabetes, annual testing is recommended using HbA1c measurements. Maternal complications Women with GDM are at an increased risk for future cardiovascular disease, T2DM, and chronic kidney disease. GDM is also associated with increased likelihood of developing pre-eclampsia following delivery. Pre-eclampsia is a complication seen in pregnancy characterized by high blood pressure, proteinuria, vision changes, and liver involvement (high LFTs). Pre-eclampsia can then progress to eclampsia or HELLP syndrome, both of which can include end organ damage. Additionally, she can develop polyhydramnios which leads to overstretching of the uterus and can induce pre-term labor, placental abruption, and or uterine atony, all of which additionally put the mother at increased risk for c-section. All of these maternal complications that stem from GDM lead to complications and extended hospitalization. Child's complications Although there is an increased set of risks for the mother, the neonate can also develop a variety of risks due to the increased glucose while in utero. While the fetus is growing, the placenta is the source of nutrition for the fetus. As the levels of glucose in the mother increase so does the amount of glucose filtered through the placenta and into the fetal circulation. Over time the glucose leads to oxidative stress and inflammation with activation of TGF-b which leads to fibroblast activation and fibrosis of the placenta. This fibrosis decreases the nutrient and oxygen exchange for the fetus. As the fetus attempts to grow in this restrictive environment its development is affected. The fetus can develop IUGR (intrauterine growth restriction) leading to a small for gestation age newborn which can then lead to another set of complications. The low oxygen environment can lead to increased EPO production and polycythemia at birth which can then lead to increased clotting that can travel to the newborn brain. Newborns can also be born with fetal acidosis due to the anerobic metabolism and lactic acid buildup in fetal tissues which can cause fetal encephalopathy leading to cerebral palsy and developmental delay. And the most severe of newborn complications to gestational diabetes can lead to fetal demise. Furthermore, the increase of glucose can also lead to macrosomia in the infant which can often lead to a traumatic delivery and delivery complications such as shoulder dystocia and brachial plexus injury. Brachial plexus injury sometimes resolves without sequela, but other times can lead to permanent weakness or paralysis of the affected arm. The baby can be born too small or too big.Additionally, once the fetus is born the cutting of the umbilical cord leads to a rapid deceleration in blood glucose in the fetal circulation and hypoglycemic episodes can occur, that often lead to NICU admission. The insulin that is created by the fetus in utero to accommodate the large quantities of glucose is known to affect lung maturation as well. The insulin produced inhibits surfactant production in the fetus. Upon birth some of the newborns also have to be placed on PEEP for ventilation and some children require treatment with surfactant to prevent alveolar collapse and/or progression to NRDS created by the low surfactant levels. Additionally, neonates who are macrosomic, which is usually seen in GDM mothers, are larger and stronger and when put on PEEP to help increase ventilation the newborn's stronger respiratory effort can lead to higher pulmonary pressures and barotrauma such as neonatal pneumothorax.Long term complications to the child of a mother with GDM also occur. As the child grows, they are also at an increased risk for developing early onset obesity because of the increased adipose storage triggered by the increase in insulin in response to the high glucose in utero. This then can lead to a higher chance of developing type 2 diabetes mellitus in the child. With diabetes, also comes an increase in cardiovascular risk as the child ages and becomes an adult. The effects of GDM go beyond the fetal life but continue through adulthood.What can be done?Gestational Diabetes Mellitus has many severe and lifelong consequences for both the mother and the child and prevention of GDM would help enhance the quality of life of both. Many of the ways to prevent GDM complications include patient education and dietary modifications with a diet rich in whole grains, fruits, vegetables and lean proteins. Benefits of some vegetables in the Mexican cuisine that may be beneficial: Nopales, Chayote, and Jicama. Those are good alternatives for highly processed carbs.Mothers are usually offered nutritional counseling to help them develop a tailored eating plan. This and 30 minutes of moderate exercise daily is recommended to increase insulin sensitivity and lower the post-prandial glucose levels. If within 2 weeks of implementing lifestyle changes alone the glucose measurements remain high, then medications like insulin can be put onboard to manage the GDM. If they require insulin, I think it is time to refer to a higher level of care, if available, high risk OB clinic.Conclusion: Now we conclude episode number ###, “[TITLE].” [summary here]. _____________________References:Eades CE, Burrows KA, Andreeva R, Stansfield DR, Evans JM. Prevalence of gestational diabetes in the United States and Canada: a systematic review and meta-analysis. BMC Pregnancy Childbirth. 2024 Mar 15;24(1):204. doi: 10.1186/s12884-024-06378-2. PMID: 38491497; PMCID: PMC10941381. https://pubmed.ncbi.nlm.nih.gov/38491497/QuickStats: Percentage of Mothers with Gestational Diabetes,* by Maternal Age — National Vital Statistics System, United States, 2016 and 2021. Weekly / January 6, 2023 / 72(1);16. https://www.cdc.gov/mmwr/volumes/72/wr/mm7201a4.htm?utmAkinyemi OA, Weldeslase TA, Odusanya E, Akueme NT, Omokhodion OV, Fasokun ME, Makanjuola D, Fakorede M, Ogundipe T. Profiles and Outcomes of Women with Gestational Diabetes Mellitus in the United States. Cureus. 2023 Jul 4;15(7):e41360. doi: 10.7759/cureus.41360. PMID: 37546039; PMCID: PMC10399637. https://pmc.ncbi.nlm.nih.gov/articles/PMC10399637/?utmPerlman, J. M. (2006). Summary proceedings from the neurology group on hypoxic-ischemic encephalopathy. Pediatrics, 117(3), S28–S33.DOI: 10.1542/peds.2005-0620C.Low, J. A. (1997). Intrapartum fetal asphyxia: definition, diagnosis, and classification. American Journal of Obstetrics and Gynecology, 176(5), 957–959.DOI: 10.1016/S0002-9378(97)70609-0.Hallman, M., Gluck, L., & Liggins, G. (1985). Role of insulin in delaying surfactant production in the fetal lung. Journal of Pediatrics, 106(5), 786–790.DOI: 10.1016/S0022-3476(85)80227-0.Sweet, D. G., Carnielli, V., Greisen, G., et al. (2019). European Consensus Guidelines on the Management of Respiratory Distress Syndrome – 2019 Update. Neonatology, 115(4), 432–450.DOI: 10.1159/000499361.Raju, T. N. K., et al. (1999). Respiratory distress in term infants: when to suspect surfactant deficiency. Pediatrics, 103(5), 903–909.DOI: 10.1542/peds.103.5.903.Burns, C. M., Rutherford, M. A., Boardman, J. P., & Cowan, F. M. (2008). Patterns of cerebral injury and neurodevelopmental outcomes after symptomatic neonatal hypoglycemia. Pediatrics, 122(1), 65–74.DOI: 10.1542/peds.2007-2822.Dabelea, D., et al. (2000). Long-term impact of maternal diabetes on obesity in childhood. Diabetes Care, 23(10), 1534–1540.DOI: 10.2337/diacare.23.10.1534.Dashe, J. S., et al. (2002). "Hydramnios: Etiology and outcome." Obstetrics & Gynecology, 100(5 Pt 1), 957–962.DOI: 10.1016/S0029-7844(02)02279-6.Long-term cost-effectiveness of implementing a lifestyle intervention during pregnancy to prevent gestational diabetes mellitus: a decision-analytic modelling study. Diabetologia.American College of Obstetricians and Gynecologists. (2018). Practice Bulletin No. 190: Gestational Diabetes Mellitus. Obstetrics & Gynecology, 131(2), e49–e64. https://doi.org/10.1097/AOG.0000000000002501Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/. 

Addiction Audio
Hidden populations in household surveys on smoking prevalence with Emma Beard

Addiction Audio

Play Episode Listen Later Jun 6, 2025 13:08


In this episode, Dr Tsen Vei Lim speaks to Dr Emma Beard, a lecturer in statistics and quantitative methods at University College London. The interview covers Emma's research report titled, ‘How much does the absence of the ‘hidden population' from United Kingdom household surveys underestimate smoking prevalence?'· How we normally estimate the smoking prevalence reported in official statistics [01:28]· Why it is important to consider the hidden population [01:55]· The consequences of not taking into account the hidden population when estimating smoking prevalence [02:35]· The ‘workbook method': how we estimate the hidden population [02:55]· The key findings and implications of these findings [03:30]· The size of the hidden population in the UK [04:42]· The huge undertaking of this research project to find these data [05:25]· The consideration of adolescent populations within smoking prevalence statistics [06:44]· What can be done within research to be more inclusive of hidden populations [07:52]· How Emma's research can contribute to policy and practice [08:44]· The argument for more and better data to include hidden populations [10:00]In Emma's paper, the hidden population for household surveys was defined as people from or living in communal establishments (e.g. care homes, student residence, prison), immigration detention centres, Gypsy, Roma and Travelling Communities, short-term accommodation, and those experiencing homelessness, including sofa surfing. About Emma Beard: Dr Beard is a Lecturer in Statistics and Quantitative Methods at University College London. She has over 130 publications on a variety of topics, with a key focus on tobacco harm reduction, high-risk alcohol consumption, and statistical methodology. Her research focuses on evaluating smoking cessation interventions and policies. She is a Deputy Methodological and Statistical Editor for the journal Addiction.About Tsen Vei Lim: Dr Tsen Vei Lim is an academic fellow supported by the Society for the Study of Addiction, currently based at the Department of Psychiatry at the University of Cambridge. His research integrates computational modelling, experimental psychology, and neuroimaging to understand the neuropsychological basis of addictive behaviours. He holds a PhD in Psychiatry from the University of Cambridge (UK) and a BSc in Psychology from the University of Bath (UK).Original editorial: How much does the absence of the ‘hidden population' from United Kingdom household surveys underestimate smoking prevalence? https://doi.org/10.1111/add.70071 The opinions expressed in this podcast reflect the views of the host and interviewees and do not necessarily represent the opinions or official positions of the SSA or Addiction journal.The SSA does not endorse or guarantee the accuracy of the information in external sources or links and accepts no responsibility or liability for any consequences arising from the use of such information. Hosted on Acast. See acast.com/privacy for more information.

Sigma Nutrition Radio
#565: How Zinc Insufficiency Impacts Inflammation, Immunity & Aging – Prof. Emily Ho

Sigma Nutrition Radio

Play Episode Listen Later Jun 3, 2025 44:28


Zinc is an essential micronutrient that often flies under the radar, despite being vital for hundreds of enzymes and transcription factors involved in immunity, antioxidant defense, and DNA repair. A surprisingly large segment of the population may not get enough – an estimated 10% of U.S. individuals consume less than half the recommended zinc intake, putting them at risk of deficiency. In this episode, Prof. Emily Ho discusses how even mild zinc insufficiency can impair immune function, promote chronic inflammation, and accelerate aspects of aging. She delves into the concept of “inflammaging” – the chronic, low-grade inflammation that develops with age – and explains how inadequate zinc status can aggravate this process. The conversation also highlights emerging research on zinc's role in DNA integrity and how restoring zinc levels can reverse certain damage, underscoring zinc's broader significance in healthy aging and disease prevention. Overall, this episode provides a deep scientific look at why maintaining adequate zinc status is crucial for immune resilience and mitigating age-related inflammatory and oxidative damage. About the Guest Emily Ho, PhD is the Director of the Linus Pauling Institute and professor in the College of Health at Oregon State University. Her research focuses on understanding the mechanisms by which nutrient status and healthy foods affect the initiation and/or progression of chronic diseases such as cancer. Her work has helped drive dietary requirements and recommendations for micronutrients such as zinc for communities with susceptibility to poor nutrition. Timestamps [02:10] Interview begins [03:58] The roles of zinc [06:31] Zinc deficiency and insufficiency [14:26] Prevalence and risk factors of zinc deficiency [21:12] Zinc and age-related inflammation [29:39] Zinc's impact on chronic diseases [31:20] Practical advice on zinc supplementation [41:14] Final thoughts Related Resources Go to episode page (includes related research) Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Linus Pauling Institute (LPI) Website Micronutrient Information Center Top 10 Micronutrients for Healthy Aging Webinars on LPI YouTube

Psychology in the Classroom
The Perils of Perfectionism: Understanding Its Impact on Mental Health in Education

Psychology in the Classroom

Play Episode Listen Later Jun 3, 2025 42:17


In this episode we explores the impact of perfectionism on exam anxiety, particularly among neurodivergent individuals. Dr. Tracey Donachie, a lecturer in sports and exercise psychology, discusses the components and prevalence of perfectionism, highlighting its psychological and behavioral effects. Maciej Matejko, from the Re-Star Project, shares his perspective on perfectionism in relation to autism, while consultant Julia Gudinchet offers strategies for managing perfectionistic tendencies in individuals with ADHD and autism. The episode provides valuable insights and practical advice for educators and students to foster healthier attitudes towards achievement. Find out more: Dr Tracy Donachie: https://www.ncl.ac.uk/psychology/people/profile/tracydonachie.html Julia Gudinchet, Sunflower Autism Consultancy: https://sunflowerautismconsultancy.co.uk Pomodoro Technique: https://changingstatesofmind.libsyn.com/how-effective-is-the-pomodoro-technique RE-STAR project (Maciej Matejko): https://www.kcl.ac.uk/research/re-star Time Stamps: Expert Insight on Perfectionism (00:01:15)   Dr. Tracey Donachie discusses her extensive experience with managing exam stress and perfectionism & explains two main components of perfectionism: high standards and self-criticism. Prevalence of Perfectionism (00:02:58)   Discussion on the rising rates of socially prescribed perfectionism among students and its debilitating effects. Good vs. Bad Perfectionism (00:06:00)   Exploration of the spectrum of perfectionism, distinguishing between striving for excellence and harmful perfectionism. Long-Term Psychological Effects (00:07:39)   Discussion on burnout and other psychological issues linked to chronic perfectionism. Impact Beyond Academics (00:09:31)   Perfectionism's effects on sports, body image, and interpersonal relationships are examined. Strategies for Teachers (00:13:49)   Recommendations for teachers to help students manage perfectionism and foster a growth mindset. Advice for Students During Exam Season (00:16:15)   Practical tips for students to combat perfectionism during high-stress exam periods.  Understanding Autism and Perfectionism (00:19:00)   Discussion on autism and its relationship with perfectionism, featuring insights from Maciej. Understanding Perfectionism in Neurodivergent Individuals (00:20:02)   Discussion on how perfectionism can stem from positive qualities but become problematic, especially for neurodivergent individuals. Perfectionism as a Coping Mechanism (00:22:20)   Exploration of how perfectionism can serve as a response to social difficulties and low self-esteem. Personal Experiences with Perfectionism (00:23:36)   Insights into the speaker's personal struggles with perfectionism and its draining effects. Advice on Managing Perfectionism (00:29:30): Changing Relationships with Failure (00:30:09)  , Exploring Interests to Reduce Pressure (00:32:14), The Need for Recovery Time (00:34:17), Exploring Neurodiversity (00:35:15), Seeking Mental Health Support (00:38:02)   Final Thoughts on Perfectionism (00:40:07)   Reflection on the need to help students foster a healthy relationship with failure and imperfection.

Frankly Speaking About Family Medicine
Can't Sleep? The Impact of Screen Time on Rest - Frankly Speaking Ep 435

Frankly Speaking About Family Medicine

Play Episode Listen Later Jun 2, 2025 11:24


Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-435 Overview: In this episode, we discuss how screen time—from adolescence through adulthood—can disrupt sleep more than we might realize. Hear what the latest research says about topics like blue light and sleep duration, discover practical strategies to sleep smarter in this digital world, and learn how sleep deprivation can impact the health of your patients. Episode resource links: Zhong, C., Masters, M., Donzella, S. M., Diver, W. R., & Patel, A. V. (2025). Electronic Screen Use and Sleep Duration and Timing in Adults. JAMA Network Open, 8(3), e252493-e252493. Liu, Y. (2016). Prevalence of healthy sleep duration among adults—United States, 2014. MMWR. Morbidity and mortality weekly report, 65. Centers for Disease Control and Prevention (CDC). (2017). Announcement: sleep awareness week, April 23–29, 2017. Morb Mortal Wkly Rep (MMWR), 66(15), 411. Chaput, J. P., Dutil, C., Featherstone, R., Ross, R., Giangregorio, L., Saunders, T. J., ... & Carrier, J. (2020). Sleep duration and health in adults: an overview of systematic reviews. Applied Physiology, Nutrition, and Metabolism, 45(10), S218-S231. Hartley, S., Royant-Parola, S., Zayoud, A., Gremy, I., & Matulonga, B. (2022). Do both timing and duration of screen use affect sleep patterns in adolescents?. Plos one, 17(10), e0276226. Salfi, F., Amicucci, G., Corigliano, D., D'Atri, A., Viselli, L., Tempesta, D., & Ferrara, M. (2021). Changes of evening exposure to electronic devices during the COVID-19 lockdown affect the time course of sleep disturbances. Sleep, 44(9), zsab080. He, J. W., Tu, Z. H., Xiao, L., Su, T., & Tang, Y. X. (2020). Effect of restricting bedtime mobile phone use on sleep, arousal, mood, and working memory: a randomized pilot trial. PloS one, 15(2), e0228756. Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

Pri-Med Podcasts
Can't Sleep? The Impact of Screen Time on Rest - Frankly Speaking Ep 435

Pri-Med Podcasts

Play Episode Listen Later Jun 2, 2025 11:24


Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-435 Overview: In this episode, we discuss how screen time—from adolescence through adulthood—can disrupt sleep more than we might realize. Hear what the latest research says about topics like blue light and sleep duration, discover practical strategies to sleep smarter in this digital world, and learn how sleep deprivation can impact the health of your patients. Episode resource links: Zhong, C., Masters, M., Donzella, S. M., Diver, W. R., & Patel, A. V. (2025). Electronic Screen Use and Sleep Duration and Timing in Adults. JAMA Network Open, 8(3), e252493-e252493. Liu, Y. (2016). Prevalence of healthy sleep duration among adults—United States, 2014. MMWR. Morbidity and mortality weekly report, 65. Centers for Disease Control and Prevention (CDC). (2017). Announcement: sleep awareness week, April 23–29, 2017. Morb Mortal Wkly Rep (MMWR), 66(15), 411. Chaput, J. P., Dutil, C., Featherstone, R., Ross, R., Giangregorio, L., Saunders, T. J., ... & Carrier, J. (2020). Sleep duration and health in adults: an overview of systematic reviews. Applied Physiology, Nutrition, and Metabolism, 45(10), S218-S231. Hartley, S., Royant-Parola, S., Zayoud, A., Gremy, I., & Matulonga, B. (2022). Do both timing and duration of screen use affect sleep patterns in adolescents?. Plos one, 17(10), e0276226. Salfi, F., Amicucci, G., Corigliano, D., D'Atri, A., Viselli, L., Tempesta, D., & Ferrara, M. (2021). Changes of evening exposure to electronic devices during the COVID-19 lockdown affect the time course of sleep disturbances. Sleep, 44(9), zsab080. He, J. W., Tu, Z. H., Xiao, L., Su, T., & Tang, Y. X. (2020). Effect of restricting bedtime mobile phone use on sleep, arousal, mood, and working memory: a randomized pilot trial. PloS one, 15(2), e0228756. Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

The Real Truth About Health Free 17 Day Live Online Conference Podcast
Explanation of Vitamin D's Role in Brain, Immune, and Nervous System Function, and the High Prevalence of Deficiency Even in Sunny Regions with Brian Clement

The Real Truth About Health Free 17 Day Live Online Conference Podcast

Play Episode Listen Later Jun 1, 2025 6:46


The Chris Voss Show
The Chris Voss Show Podcast – Inside Shameless Care: Revolutionizing Sexual Health Testing

The Chris Voss Show

Play Episode Listen Later May 30, 2025 53:41


Inside Shameless Care: Revolutionizing Sexual Health Testing shamelesscare.com About the Guest(s): Robert Johnson is the founder of Shameless Care, a pioneering telemedicine company that specializes in delivering sexual healthcare tailored for real-life needs. After a personal experience with an STI test failing to detect an infection, Robert launched Shameless Care to offer comprehensive and judgment-free telemedicine services. His company focuses on thorough STI testing, inclusive of all potential infection sites, and has been leading efforts in providing honest and accessible sexual health resources. Robert's background is steeped in entrepreneurship and he is dedicated to improving healthcare by addressing gaps in traditional testing methods. Episode Summary: In this episode of The Chris Voss Show, listeners embark on an informative journey into the world of telemedicine and sexual health with Robert Johnson, founder of Shameless Care. Highlighted by enlightening anecdotes and expert insights, the conversation navigates through the complexities of STI testing, the rise of telemedicine, and how these innovations are transforming the landscape of sexual healthcare. This episode shines a light on the crucial importance of thorough STI testing, addressing often-overlooked aspects such as oral and anal infection sites that remain asymptomatic and consequently contribute to the spread of infections. Throughout the discussion, Robert Johnson emphasizes Shameless Care's commitment to enhancing sexual health through patient transparency and comprehensive service offerings. With the increasing prevalence of STIs, Robert argues for greater awareness and proactive measures, dispelling myths and shedding light on underrepresented issues within sexual healthcare. This conversation also touches upon societal and technological shifts influencing sexual behavior and healthcare, including how telemedicine is paving new pathways for privacy and honesty in patient-doctor interactions. Through engaging dialogue, the episode underscores the transformative impact and potential of telemedicine in creating a world where sexual health is accessible and stigma-free. Key Takeaways: Comprehensive STI Testing: Shameless Care stands out for its rigorous testing of 14 STIs, including often-neglected sites like the throat and anal areas, which can harbor infections asymptomatically. Privacy and Transparency in Telemedicine: The telemedicine model permits patients to discuss their health issues openly and without judgment, ensuring more accurate diagnoses and appropriate treatments. Prevalence of Asymptomatic Cases: Many STIs present without symptoms; thus, regular and thorough testing is essential for prevention and control. Innovations in Sexual Healthcare: Products like topical Viagra for women and Doxy PEP pills exemplify emerging solutions targeted at enhancing sexual health and prevention. Healthcare Accessibility and Education: Shameless Care's approach is educational and preventative, encouraging personal responsibility and safe sexual practices among users. Notable Quotes: "80% of our positive gonorrhea cases are oral only, caught only with that oral swab." "You can be completely honest with your doctor, and everybody should be honest with their doctor." "It's surprising how many times a married couple will order tests at the same time, get their test results back and not test positive for the same thing." "We're just really proud that we can offer a list of infections to help people get quality testing from their physicians." "Testing thoroughly is one of the most important actions people in the dating pool can take."

Celeste The Therapist Podcast
EP 513 Turning Pain into Purpose: Reframing Your Life

Celeste The Therapist Podcast

Play Episode Listen Later May 28, 2025 29:26 Transcription Available


Welcome to another episode of "Celeste the Therapist Podcast"! I'm Celeste, a therapist from Boston, and if you're new here, thank you for tuning in. For our longtime listeners, I appreciate your continued support. On this podcast, I delve into the challenges we face in life and provide insights on how to navigate them. Whether you're here to shift your mindset or embark on a healing journey, this episode is designed to offer holistic approaches and practical advice. This week, I encourage you to grab a notebook and a pen to jot down key takeaways. Remember, take what resonates with you and leave what doesn't. My goal is to provide you with valuable resources to aid your personal growth. Exciting news: I'm celebrating another anniversary of the podcast, which started on July 2, 2018. Additionally, I now run a wellness center in Stoughton, Massachusetts. If you're nearby, visit us at stwit.com for more information. For those who prefer visual content, this episode is also available on YouTube where I incorporate visuals to enhance your learning experience. Tune in to learn more about starting where you are, using what you have, and working towards a better mindset. Thank you for joining, and let's get started on this week's episode! [00:02:52] Reframing your life. [00:03:45] Reframing pain into purpose. [00:07:42] Understanding the impact of your past [00:12:09] Prevalence of anxiety and depression. [00:16:49] Reframing job loss. [00:19:09] Going for my license. [00:22:28] Healing is your responsibility. [00:26:32] Healing is your responsibility.

JACC Speciality Journals
Cardiomyopathy Prevalence and Pregnancy-Related Mortality: United States, 2010 to 2020 | JACC: Advances

JACC Speciality Journals

Play Episode Listen Later May 28, 2025 2:36


Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Cardiomyopathy Prevalence and Pregnancy-Related Mortality: United States, 2010 to 2020.

JACC Speciality Journals
Prevalence, Risk Factors, and Prognosis for Fontan-Associated Liver Disease: A Systematic Review and Exploratory Meta-Analysis | JACC: Advances

JACC Speciality Journals

Play Episode Listen Later May 28, 2025 2:55


Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Prevalence, Risk Factors, and Prognosis for Fontan-Associated Liver Disease: A Systematic Review and Exploratory Meta-Analysis.

At The Table with Patrick Lencioni
243. Overcoming the "I'm Not Enough" Trap

At The Table with Patrick Lencioni

Play Episode Listen Later May 27, 2025 22:55


Why do so many successful leaders struggle with the feeling of "not being enough"? And how can leaders shift away from a scarcity mindset?In episode 243 of At The Table, Patrick Lencioni and Cody Thompson explore the pervasive feeling of inadequacy among leaders. They discuss how a "not enough" mindset can drive individuals to seek validation through constant achievement. The conversation emphasizes the importance of vulnerability, self-awareness, and shifting from a fear-based to a joy-based approach to life and work.Topics explored in this episode: (0:49) The Prevalence of "I'm Not Enough"* Many leaders share a common feeling of inadequacy, often tracing it back to their youth. * This feeling can create a cycle of constantly striving to prove yourself, hindering your ability to find satisfaction in accomplishments. (5:04) The Impact of Vulnerability* Sharing your feelings of inadequacy with others can normalize these experiences, encouraging them to acknowledge their own struggles and seek support. (9:07) The Scarcity Mindset* Believing "I'm not enough" can lead to a scarcity mindset, affecting your perceptions of time, success, and resources. (14:23) The Illusion of Control* The pursuit of control over outcomes can lead to anxiety and prevent you from embracing the present moment. (18:36) Finding Peace in the Journey* Reframing your perspective can help you foster a sense of peace. * Embracing the journey and finding joy in the process can lead to greater fulfillment than solely focusing on the result.This episode of At The Table with Patrick Lencioni is brought to you by The Table Group: https://www.tablegroup.com. We teach leaders how to make work more effective and less dysfunctional. We also help their employees be more fulfilled and less miserable. At The Table is a podcast that lives at the connection between work life, leadership, organizational health, and culture. Subscribe on Apple Podcasts (https://apple.co/4hJKKSL), Spotify (https://spoti.fi/4l1aop0), and YouTube (https://bit.ly/At-The-Table-YouTube). Follow Pat Lencioni on https://www.linkedin.com/in/patrick-lencioni-orghealth and http://www.youtube.com/@PatrickLencioniOfficial. Connect with Cody Thompson https://www.linkedin.com/in/cody-thompson-a5918850. Be sure to check out our other podcast, The Working Genius Podcast with Patrick Lencioni, on Apple Podcasts (https://apple.co/4iNz6Yn), Spotify (https://spoti.fi/4iGGm8u), and YouTube (https://bit.ly/Working-Genius-YouTube). Let us know your feedback via podcast@tablegroup.com. This episode was produced by Story On Media:

Lara Briden's Podcast
The hidden story of endometriosis: Pain, lesions, and the microbiome

Lara Briden's Podcast

Play Episode Listen Later May 27, 2025 15:37 Transcription Available


If you've been diagnosed with endometriosis, the big question is: What type of lesions?In this episode, Lara challenges long-held assumptions to explore:the three types of endometriosis lesions, emerging evidence that superficial lesions may not explain pain or other symptoms, alternative explanations for pelvic pain and infertility, including pelvic congestion, immune dysfunction, and gut microbiome imbalance, and an update on the bacterial contamination hypothesis.Links:Could pelvic congestion syndrome explain your pelvic pain?Prevalence of endometriosis in asymptomatic women (1991 study)Surgical removal of superficial peritoneal endometriosis for managing women with chronic pelvic pain: time for a rethink? (2019 BJOG article)Bacterial contamination hypothesis (2018 paper)Fusobacterium infection facilitates the development of endometriosis (2023 paper)ANZCA 2024 Statement on pelvic pain and endometriosis 

My Happy Thyroid
Ep. 191: Could Your Teenager Be Hypothyroid?

My Happy Thyroid

Play Episode Listen Later May 27, 2025 7:30


Could your tired, moody, always-cold teenager actually have a thyroid problem? While we often chalk up things like fatigue, mood swings, and sleeping until noon as “just being a teen,” an underactive thyroid – called hypothyroidism –  could be playing a role. And the earlier you catch it, the better your teen can feel—physically and emotionally.In this episode, we're exploring the signs and symptoms of hypothyroidism in teenagers, and what you can do to get them back to good health.What you'll learn: Prevalence of hypothyroidism in teenagers⁠⁠ Causes of hypothyroidism in teenagers⁠⁠ Recognizing the symptoms of hypothyroidism in teenagers⁠⁠ Diagnosing hypothyroidism in teenagers⁠⁠ Treating hypothyroidism in teenagers⁠⁠ Challenges for teenagers⁠Check out our blog and read the full article here: https://www.palomahealth.com/learn/hypothyroidism-teenagersAbout Paloma Health:⁠⁠Paloma Health ⁠⁠⁠⁠⁠⁠⁠⁠is an online medical practice focused exclusively on treating hypothyroidism. From online visits with your provider to easy prescription management and lab orders, we create personalized treatment plans for you. Become a member⁠, or try our at-home test kit and experience a whole new level of hypothyroid care. Use code PODCAST to save $30 at checkout.Disclaimer: The $30 discount is only valid for first-time Paloma Health members and test kit users. Coupon must be entered at the time of checkout. Become a Paloma Member:https://www.palomahealth.com/pricing-hypothyroidism Paloma Complete Thyroid Blood Test Kit:https://www.palomahealth.com/home-thyroid-blood-test-kit

VETgirl Veterinary Continuing Education Podcasts
Prevalence of Acute Kidney Injury and Outcome in Cats Treated as Inpatients Versus Outpatients Following Lily Exposure | VETgirl Veterinary Continuing Education Podcasts

VETgirl Veterinary Continuing Education Podcasts

Play Episode Listen Later May 26, 2025 20:59


In today's VETgirl online veterinary CE podcast, Dr. Erica Reineke, DACVECC discusses the prevalence of acute kidney injury and outcome in cats who ingested lilies when they are treated as inpatients compared to outpatients. If we treat our feline nephrotoxicant patients outpatient, will it decrease survival? Tune in to learn what you need to know regarding lily exposure in cats when deciding to treat them in or out of the hospital!

Health & Veritas
Rebekah Gee: Improving Health, One Family at a Time

Health & Veritas

Play Episode Listen Later May 22, 2025 40:03


Howie and Harlan are joined by Rebekah Gee, founder and CEO of Nest Health, which provides in-home care to kids on Medicaid and their families. Harlan reports on the first personalized CRISPR gene therapy for a rare genetic disease; Howie untangles the FDA's restrictions on the COVID-19 booster and what it will mean for your ability to get a shot this fall.  Links: A Breakthrough CRISPR Treatment “Baby Is Healed With World's First Personalized Gene-Editing Treatment” “Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease” “Progress in the Development of N-of-1 Therapy” “Personalized Gene Editing to Treat an Inborn Error of Metabolism” Nest Health Health & Veritas Episode 40: Rebekah Gee: Can We Bring Family Healthcare to the Home? Nest Health “Nest Health picks up $4M in seed extension funding to build out at-home primary care for families” “How Nest Health Is Redefining Primary Care for Families” Rebekah Gee on LinkedIn on Nest Health “What ‘patient-centered‘ should mean: confessions of an extremist” “Prevalence and Variation of Developmental Screening and Surveillance in Early Childhood” “Postpartum health is in crisis” “The Impact of the Pandemic on Well-Child Visits for Children Enrolled in Medicaid and CHIP” “Families often have chief medical officers—and they're almost always women” “Case Study: Louisiana's Poor Rankings Make Improving Birth Outcomes a State Imperative” “In 6-to-3 Ruling, Supreme Court Ends Nearly 50 Years of Abortion Rights” Rebekah Gee on LinkedIn on Medicaid cuts “5 Key Facts About Medicaid Work Requirements” “Health Provisions in the 2025 Federal Budget Reconciliation Bill” A New COVID Booster Policy “An Evidence-Based Approach to Covid-19 Vaccination” “FDA will limit Covid vaccines to people over 65 or at high risk of serious illness, leaders say” “FDA tightens requirements for COVID vaccine, adding trials for healthy adults” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Pediatric Meltdown
247. Human Trafficking: What Pediatric Clinicians Must Know

Pediatric Meltdown

Play Episode Listen Later May 21, 2025 60:54


Have you ever considered that victims of human trafficking might be walking into your clinic, hidden in plain sight, longing for someone to notice their silent signals? In this episode of Pediatric Meltdown, host Dr. Lia Gaggino sits down with Dr. Dena Nazer , a leading child abuse pediatrician, to dispel widespread myths and expose the heartbreaking realities of child trafficking. They dive deeply into what human trafficking truly looks like, why language and empathy shape outcomes, and how pediatricians can recognize and respond to red flags—even when victims don't or can't ask for help. If you've ever wondered how to protect the most vulnerable or questioned your own role in advocacy, this conversation mixes expertise and actionable strategies you can use today. Don't miss this essential episode—sometimes the most critical intervention is simply being prepared to see what others overlook.[00:00 - 06:25] Beyond Kidnapping: The Everyday Reality of Child TraffickingMedia Myths: trafficking is not always dramatic kidnappings—many victims are exploited by someone they know, sometimes in their own homes.Defining human trafficking per US federal law: for children under 18, any commercial sexual act (anything exchanged for perceived value) is trafficking, regardless of force, fraud, or coercion.Labor trafficking in children does require proof of force, fraud, or coercion, unlike sex trafficking.Children cannot legally consent to commercial sexual acts, a fact often misunderstood by practitioners.[06:26 - 18:33] Recognizing Vulnerability: Victims, Prevalence, and Persistent MythsAll children, regardless of socioeconomic status or geography, can be victimized; not just those from impoverished or unstable backgrounds.Adolescents are particularly vulnerable due to developmental, social, and neurological factors—especially girls, though all genders are at risk.The covert nature and underreporting of trafficking, with true prevalence grossly underestimated—actual victims far exceed documented cases.Practitioners should avoid assumptions about victim profiles and recognize that trafficking does not discriminate by background or location.[18:34 -24:41] Language, Reporting, and the Power of EmpathyThere is an impact of language, advocating against terms like "prostitute" or "modern day slavery," as they distort public perception and can harm survivors.There are nuanced preferences between “victim” and “survivor,” emphasizing respect for self-identification.Addresses mandated reporting: outlines state-by-state differences, reminds clinicians to know their local laws, and suggests erring on the side of caution when in doubt.Discusses the complexities of reporting and intervention with 18+ patients, promoting support over “rescue,” and collaboration over dictating solutions.[24:42 - 47:58] Identification, Patient Support, and Multi-Agency CollaborationRed flags in clinical settings: domineering non-parental adults accompanying children, delayed care-seeking, lack of address knowledge, repeated STIs, or signs of fear and withdrawal.Ways to build trust and elicit disclosures: prioritize safety, establish boundaries about reporting, and use risk-factor-based screening questions.Trauma-informed care—responding with empathy, validation, and minimal dramatization—to avoid re-traumatizing patients.Connect with local Child Advocacy Centers and understanding local resources and procedures before a crisis arises.[47:59 - 59:59] Dr. G's TakeAwaysAdditional Resources Mentioned

Identity At The Center
#350 - Sponsor Spotlight - SlashID

Identity At The Center

Play Episode Listen Later May 21, 2025 46:56


This episode is sponsored by SlashID. Visit https://www.slashid.com/idac to learn more.In this sponsored episode of the Identity at the Center Podcast, hosts Jeff and Jim interview Vincenzo Iozzo, CEO of SlashID, to discuss the current landscape and innovations they are making in Identity and Access Management (IAM). Vincenzo, who has a background in offensive security and experience at CrowdStrike, explains how SlashID uses Large Language Models (LLMs) to enhance visibility and posture beyond traditional Identity Governance and Administration (IGA) and Privileged Access Management (PAM) tools. Slash ID focuses on real-time detection and response to identity-based threats, addressing gaps that compliance-driven IGA systems miss. The episode also covers the advantages of SlashID's platform, including monitoring privileged identities, automating policy generation for least privilege, and integrating with existing security infrastructure. The conversation delves into the challenges of identity-related breaches and the importance of balancing compliance with robust security measures. Vincenzo also shares his experiences from the offensive security world, including hacking competitions and the evolving threat landscape.Timestamps00:00 Introduction to Real-Time Identity Security01:20 Welcome to the Identity at the Center Podcast02:18 Meet Vincenzo Iozzo, CEO of SlashID02:37 Vincenzo's Journey into Digital Identity04:26 The Genesis of SlashID08:16 Challenges in Identity Governance and Administration (IGA)14:41 The Prevalence of Identity-Related Breaches19:06 Detection and Response Strategies24:30 Lifecycle Issues Detection26:11 Remediation Strategies28:57 Integration with Existing Tools30:27 Customer Success Metrics34:10 Setting Up and Deploying SlashID35:48 Live Demo Walkthrough41:48 Challenges in Cybersecurity45:16 Final Thoughts and Contact InformationConnect with Vincenzo: https://www.linkedin.com/in/vincenzoiozzo/Learn more about SlashID: https://www.slashid.com/idacConnect with us on LinkedIn:Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/Visit the show on the web at idacpodcast.com and watch at https://www.youtube.com/@idacpodcast

True Birth
Unicornuate Uterus: Episode #181

True Birth

Play Episode Listen Later May 20, 2025 25:41


Understanding Unicornuate Uterus: What It Is, Prevalence, Risks, and a Positive Outlook A unicornuate uterus is a rare congenital condition where the uterus develops with only one half, or "horn," instead of the typical two-horned shape of a normal uterus. This happens during fetal development when one of the Müllerian ducts, which form the uterus, fails to develop fully. As a result, the uterus is smaller, has only one functioning fallopian tube, and may or may not have a rudimentary horn (a small, underdeveloped second horn). This condition falls under the category of Müllerian duct anomalies, which affect the female reproductive tract. For those diagnosed, understanding the condition, its implications, and the potential for a healthy pregnancy can provide reassurance and hope.   What Is a Unicornuate Uterus? The uterus typically forms as a pear-shaped organ with two symmetrical halves that fuse during fetal development. In a unicornuate uterus, only one half develops fully, creating a smaller-than-average uterine cavity. This anomaly can occur with or without a rudimentary horn, which may or may not be connected to the main uterine cavity. If a rudimentary horn is present, it might cause complications like pain if it accumulates menstrual blood, as it often lacks a connection to the cervix or vagina. The condition is often diagnosed during routine imaging, such as an ultrasound, MRI, or hysterosalpingogram (HSG), typically when a woman seeks medical advice for fertility issues, pelvic pain, or irregular menstruation. In some cases, it's discovered incidentally during pregnancy or unrelated medical evaluations.   How Prevalent Is It? Unicornuate uterus is one of the rarest Müllerian duct anomalies, occurring in approximately 0.1% to 0.4% of women in the general population. Among women with Müllerian anomalies, it accounts for about 2% to 13% of cases. The condition is congenital, meaning it's present at birth, but it often goes undiagnosed until adulthood because many women experience no symptoms. Its rarity can make it feel isolating for those diagnosed, but awareness and medical advancements have made it easier to manage and understand. Risks Associated with Unicornuate Uterus While many women with a unicornuate uterus lead healthy lives, the condition can pose challenges, particularly related to fertility and pregnancy. The smaller uterine cavity and reduced endometrial surface area can increase the risk of certain complications, though these are not inevitable. Below are some potential risks: Fertility Challenges: The smaller uterus and single fallopian tube may slightly reduce the chances of conception, especially if the rudimentary horn or other structural issues interfere with ovulation or implantation. However, many women with a unicornuate uterus conceive naturally without intervention. Miscarriage: The limited space in the uterine cavity can increase the risk of miscarriage, particularly in the first trimester. Studies suggest miscarriage rates may be higher (around 20-30%) compared to women with a typical uterus, though exact figures vary. Preterm Birth: The smaller uterus may not accommodate a growing fetus as easily, potentially leading to preterm labor or delivery before 37 weeks. Research indicates preterm birth rates in women with a unicornuate uterus range from 10-20%. Fetal Growth Restriction: The restricted uterine space can sometimes limit fetal growth, leading to low birth weight or intrauterine growth restriction (IUGR). Malpresentation: Babies in a unicornuate uterus may be more likely to position themselves in a breech or transverse position due to the confined space, which could complicate delivery. Cesarean Section: While not mandatory, a cesarean may be recommended in cases of malpresentation, preterm labor, or other complications. However, this is not a universal requirement. Other Complications: Women with a unicornuate uterus may have a higher risk of endometriosis or painful periods, especially if a non-communicating rudimentary horn is present. Kidney abnormalities are also associated with Müllerian anomalies, as the kidneys and reproductive tract develop simultaneously in the fetus. Despite these risks, it's critical to note that not every woman with a unicornuate uterus will experience these complications. With proper medical care, many achieve successful pregnancies and deliveries.   A Positive Outlook: Normal Vaginal Delivery Is Probable The diagnosis of a unicornuate uterus can feel daunting, but it's important to emphasize that a healthy, full-term pregnancy and a normal vaginal delivery are entirely possible. Advances in obstetrics and prenatal care have significantly improved outcomes for women with this condition. Here's why you can remain optimistic: Personalized Care: Working with an experienced obstetrician or maternal-fetal medicine specialist ensures close monitoring throughout pregnancy. Regular ultrasounds can track fetal growth, position, and amniotic fluid levels, allowing for timely interventions if needed. Not Doomed to Cesarean: While some women may need a cesarean due to specific complications, many with a unicornuate uterus deliver vaginally without issue. The decision depends on factors like fetal position, labor progression, and overall health, not the uterine anomaly alone. Full-Term Pregnancies Are Achievable: With careful monitoring, many women carry their pregnancies to term (37-40 weeks). Preterm birth is a risk, but it's not a certainty, and modern neonatal care can support babies born slightly early if needed. Healthy Babies: Countless women with a unicornuate uterus give birth to healthy, thriving babies. The condition does not inherently affect the baby's development or genetic health. Support and Advocacy: Connecting with others who have similar experiences, whether through online communities or support groups, can provide emotional strength and practical advice. Knowing you're not alone can make all the difference. A unicornuate uterus is a rare but manageable condition that requires awareness and, in some cases, specialized care. While there are risks to consider, they are not insurmountable, and many women with this anomaly experience successful pregnancies and vaginal deliveries without complications. With the right support, you can embrace your unique journey, knowing that a unicornuate uterus does not mean you're destined for preterm birth, cesarean delivery, or pregnancy complications. Instead, it's a testament to your resilience and the incredible capabilities of modern medicine to support you every step of the way.   Connect With Us: YouTube: Dive deeper into pregnancy tips and stories atyoutube.com/maternalresources . Instagram: Follow us for daily inspiration and updates at @maternalresources . Facebook: Join our community at facebook.com/IntegrativeOB Tiktok: NatureBack Doc on TikTok Grab Our Book! Check out The NatureBack Method for Birth—your guide to a empowered pregnancy and delivery. Shop now at naturebackbook.myshopify.com .    

Research To Practice | Oncology Videos
5-Minute Journal Club Issue 7 with Dr Rinath M Jesselsohn: Reviewing the Role of Oral SERDs in the Management of ER-Positive Metastatic Breast Cancer

Research To Practice | Oncology Videos

Play Episode Listen Later May 19, 2025 17:35


Featuring an interview with Dr Rinath M Jesselsohn, including the following topics: Imlunestrant with or without abemaciclib in advanced breast cancer: Results of the Phase III EMBER-3 trial (0:00) Jhaveri KL et al. Imlunestrant with or without abemaciclib in advanced breast cancer. N Engl J Med 2025;392(12):1189-202. Abstract  Jhaveri KL et al. Imlunestrant, an oral selective estrogen receptor degrader (SERD), as monotherapy & combined with abemaciclib, for patients with ER+, HER2- advanced breast cancer (ABC), pretreated with endocrine therapy (ET): Results of the Phase 3 EMBER-3 trial. San Antonio Breast Cancer Symposium 2024;Abstract GS1-01. Comprehensive genomic profiling of ESR1, PIK3CA, AKT1 and PTEN in HR-positive, HER2-negative metastatic breast cancer: Prevalence along treatment course and predictive value for endocrine therapy resistance in real-world practice (7:00) Bhave MA et al. Comprehensive genomic profiling of ESR1, PIK3CA, AKT1, and PTEN in HR(+)HER2(-) metastatic breast cancer: Prevalence along treatment course and predictive value for endocrine therapy resistance in real-world practice. Breast Cancer Res Treat 2024;207(3):599-609. Abstract Camizestrant, a next-generation oral selective estrogen receptor degrader (SERD), versus fulvestrant for postmenopausal women with estrogen receptor-positive, HER2-negative advanced breast cancer (SERENA-2): A multi-dose, open-label, randomized, Phase II trial (10:25) Oliveira M et al. Camizestrant, a next-generation oral SERD, versus fulvestrant in post-menopausal women with oestrogen receptor-positive, HER2-negative advanced breast cancer (SERENA-2): A multi-dose, open-label, randomised, phase 2 trial. Lancet Oncol 2024;25(11):1424-39. Abstract Latest on SERDs: An education session at San Antonio Breast Cancer Symposium 2024 (13:57) Jeselsohn RM. Latest on selective estrogen receptor degraders (SERDs). San Antonio Breast Cancer Symposium 2024;Education Session 5. CME information and select publications

Public Health On Call
894 - Is There an Autism Epidemic?

Public Health On Call

Play Episode Listen Later May 15, 2025 12:53


About this episode: Diagnoses of autism are on the rise, but is this the result of more children being affected by the condition, or is more of a consequence of broader criteria and more screening? In this episode: a look at a new study about the number of children diagnosed with autism and what this research shows—and doesn't show. Guest: Dr. Christine Ladd-Acosta is an autism researcher and vice-director of the Wendy Klag Center for Autism and Developmental Disabilities. She is the lead Maryland investigator on a national study about the rate of autism. Host: Dr. Josh Sharfstein is vice dean for public health practice and community engagement at the Johns Hopkins Bloomberg School of Public Health, a faculty member in health policy, a pediatrician, and former secretary of Maryland's Health Department. Show links and related content: Prevalence and Early Identification of Autism Spectrum Disorder Among Children Aged 4 and 8 Years - Autism and Developmental Disabilities Monitoring Network, 16 Sites, United States 2022—CDC's MMWR RFK Jr.'s autism study to amass medical records of many Americans—CBS News The NIH-Funded Autism Study Hoping to Pinpoint Gene-Environmental Interplay—Public Health On Call (March 2025) Vaccines Don't Cause Autism. Why Do Some People Think They Do?—Hopkins Bloomberg Public Health Discovering How Environment Affects Autism—Hopkins Bloomberg Public Health Magazine (2023) Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @‌PublicHealthPod on Bluesky @‌JohnsHopkinsSPH on Instagram @‌JohnsHopkinsSPH on Facebook @‌PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.

How Preschool Teachers Do It
329: The Continuing Prevalence of Name Calling with Cindy and Alison

How Preschool Teachers Do It

Play Episode Listen Later May 12, 2025 16:47


The biter, the hitter, the runner, the climber...Why do some adults continue to label children this way? Would you do that to an adult? Join Cindy and Alison for a reflection on why this happens and what we can do.

Autism Live
Autism Live 5.12.25: The Prevalence Show with Lisa Ackerman

Autism Live

Play Episode Listen Later May 12, 2025 61:51


TACA founder Lisa Ackerman joins Shannon to shed light on the new Autism Prevalence numbers released by the CDC in April.

cdc prevalence taca autism live lisa ackerman
Brain Biohacking with Kayla Barnes
Endometriosis with Dr. Sasha Hakman

Brain Biohacking with Kayla Barnes

Play Episode Listen Later May 8, 2025 87:46


Today I'm speaking with Dr. Sasha Hakman on the Longevity Optimization Podcast. In this conversation, we discuss endometriosis, a condition affecting approximately 10% of women, characterized by the presence of endometrial cells outside the uterus. Dr. Hakman explains the definition, symptoms, and prevalence of the condition, as well as the challenges involved in diagnosing it. She also explores potential causes, including genetic and environmental factors, and discusses various treatment options. The conversation emphasizes the importance of understanding endometriosis, its impact on fertility, and the need for increased awareness and proactive care.Dr. Sasha Hakman is a respected expert in women's health, specializing in reproductive medicine and chronic conditions like endometriosis. With a strong background in both clinical practice and research, she is dedicated to advancing knowledge and treatment options for women affected by complex gynecological issues. Dr. Hakman is passionate about educating patients and healthcare providers alike, aiming to improve diagnosis, management, and overall outcomes for women's reproductive health.Let's be friends!Instagram: https://www.instagram.com/kaylabarnes/?hl=enTikTok: https://www.tiktok.com/@femalelongevityX: https://x.com/femalelongevityWebsite: https://kaylabarnes.comJoin Female Longevity Community: https://kayla-barnes-lentz.circle.so/checkout/become-a-member Follow Dr. Sasha Hakman:Instagram: https://www.instagram.com/sashahakmanmd/?hl=enTikTok: https://www.tiktok.com/@dr.fierceWebsite: https://sashahakmanmd.com/Timestamps00:00 Introduction to Endometriosis02:54 Understanding Endometriosis: Definition and Mechanism06:04 Prevalence and Diagnosis Challenges09:14 Symptoms and Impact on Fertility11:59 Potential Causes and Theories14:55 Genetic and Environmental Factors18:05 Treatment Options and Management21:03 Lifestyle and Dietary Considerations23:56 Future Directions in Research and Treatment32:39 Understanding Endometriosis Treatment Options43:09 Common Misconceptions About Endometriosis48:43 Navigating Healthcare for Endometriosis51:45 Complementary Therapies and Lifestyle Adjustments56:02 Future Directions in Endometriosis Research01:01:16 The Importance of Gut Health01:04:54 Cycle Syncing and Nutrition01:06:40 Exploring Alternative Treatments for Endometriosis01:10:01 The Role of Medications in Managing Endometriosis01:12:06 Understanding Endometriosis and Autoimmune Conditions01:15:00 Differentiating Between Endometriosis and Endometritis01:20:23 Hormonal Treatments and Their Impact01:21:15 Improving Fertility with Endometriosis01:22:33 Understanding PCOS vs. Endometriosis01:24:01 Managing Pain and Symptoms of Endometriosis

Heal Thy Self with Dr. G
When No One Tells You About Herpes! #378

Heal Thy Self with Dr. G

Play Episode Listen Later May 5, 2025 26:47


Over 70% of the world has herpes—yet it's still taboo. In this episode, Dr. G breaks down the truth about HSV-1 & HSV-2, from how it spreads to how to heal physically and emotionally. He shares the Heal Thyself protocol, featuring powerful supplements, nervous system tools, and mindset shifts to reduce outbreaks and reclaim your peace. #wellnessjourney #herpes #wellness ==== Thank You To Our Sponsors! Calroy Head on over to at calroy.com/drg and Save over $50 when you purchase the Vascanox and Arterosil bundle! ==== Timestamps: 00:00:00 - Understanding the Herpes Virus 00:02:56 - Prevalence, Latency & Treatment 06:00 - Transmission: Myths & Facts 08:58 - Triggers, Treatments & Misconceptions 12:02:47 - Antiviral Drugs & Holistic Healing 15:09 - Treatment: Sleep, Stress & Supplements 18:09 - Natural Herpes Remedies 21:15 - Treatment & Emotional Roots 24:10 - Healing Herpes: Shame & Self-Ownership Be sure to like and subscribe to #HealThySelf Hosted by Doctor Christian Gonzalez N.D. Follow Doctor G on Instagram @doctor.gonzalez https://www.instagram.com/doctor.gonzalez/ Sign up for our newsletter! https://drchristiangonzalez.com/newsletter/

UAB MedCast
The Rising Prevalence of Kidney Stones: What Should Clinicians Know?

UAB MedCast

Play Episode Listen Later May 5, 2025


Kidney stones are often more than a one-time painful event: they're a chronic disease linked to other health issues. Kyle Wood, M.D., discusses how stone disease often coexists with conditions like hypertension, dietary imbalance, and primary hyperparathyroidism. He explains that reviewing patient history, taking bloodwork, and ordering urine testing can help providers understand a patient's overall risk for stone recurrence and related chronic conditions. Learn how UAB uses genetic testing to identify heritable causes of stone disease in patients with early onset, recurrence, or other red flags.