Podcasts about pravachol

A study looking at people with genetic variants that mimic the effect of statins and PCSK9 inhibitors showed significantly worse cognition and brain area among those with the statin variants. This suggests that statins may negatively impact the brain (PMID 35953131).This suggests that important benefits to cerebrovascular disease may be counterbalanced by other negative effects on the brain by statins through other mechanisms.An important caveat to the study is that while these statin-mimicking variants are expressed everywhere in the body in people who have inherited them, different statins have a different degree of selectivity for the liver versus other tissues (such as the brain).Statins that are selective for the liver are called hydrophilic, while those that are nonspecific and inhibit HMGCR in all tissues (including the brain) are called lipophilic.This is because lipophilic statins freely travel across cell membranes, while hydrophilic statins need to be transported into liver cells using transporters (OATP1B1, OATP1B3, OATP2B1, BCRP, and MRP2) expressed only in the liver (PMID: 29051147).Interestingly, another recent study found that statin users with mild cognitive impairment using lipophilic statins had an increased risk of converting to dementia compared to non-users and users of hydrophilic statins (https://jnm.snmjournals.org/content/62/supplement_1/102).This same study found using FDG PET a decline in metabolism in several regions of the brain important for cognition in those using lipophilic statins but not non-users or users of hydrophilic statins.While no strong, gold standard evidence implicates lipophilic statins as harmful for brain health, given the wide availability of similarly priced alternatives, these findings might suggest that hydrophilic statins should be preferred to lipophilic ones whenever possible. The hydrophilic statins are pravastatin (Pravachol) and rosuvastatin (Crestor), while the lipophilic statins are fluvastatin (Lescol), lovastatin (Mevacor, Altoprev), simvastatin (Zocor), atorvastatin (Lipitor), and pitavastatin (Livalo).===Like, comment, subscribe.For more, find me at:PODCAST The Kevin Bass ShowYOUTUBE https://www.youtube.com/user/kbassphiladelphiaSUBREDDIT www.reddit.com/r/kevinbassWEBSITE http://thedietwars.comTWITTER https://twitter.com/kevinnbass/https://twitter.com/healthmisinfo/INSTAGRAM https://instagram.com/kevinnbass/TIKTOK https://tiktok.com/@kevinnbassAnd above all, please donate to support what I do:PATREON https://patreon.com/kevinnbass/DONATE https://thedietwars.com/support-me/

Statins, prescribed to lower cholesterol levels, are not without a major downside. As always, this is not medical advice, and I urge you to have a conversation with your doctor if you have been prescribed statins; popular names include Lipitor, Crestor, Zocor, Pravachol amongst others. Common side effects of these drugs include: muscle pain and fatigue, increase in type II diabetes, liver & kidney damage, memory loss and confusion and more. If you are taking a statin it is recommended that you supplement with 100-300 mg CoQ10. https://drsarahbrewer.com/statins-and-co-enzyme-q10 Here is a good place to start your research: https://bit.ly/MayoStatins but you can simple type "statin side effects" into google and choose where you would like to learn your information from. It's always a good idea to do your own research and advocate for yourself.  Your doctor should be open to have a discussion with you about your wellness and your health concerns.

David Brownstein, M.D. is a Board-Certified family physician and one of the foremost practitioners and speakers of holistic medicine. Dr. Brownstein has practiced holistic medicine for 25 years, has 16 books out, many of them best-sellers. In this dynamic and personal dialogue between two colleagues and dear friends,  you will learn: What are the most accurate ways to assess cholesterol. What are ideal cholesterol levels. Why do cardiologists recommend statins when the statistical science is so poor. Statins include atorvastatin (Lipitor), fluvastatin (Lescol XL), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastatin (Crestor, Ezallor) and simvastatin (Zocor, FloLipid). Learn the most common side effects and the underlying mechanisms. Statins increase calcium score numbers: what this is and why you should care. Relative versus accurate statistical significance. The role of thyroid and hormones in heart health. Thyroid resistance, what it is, what labs look like and how you treat it . How Dr. Brownstein trains medical students to learn this information. And more! Links: https://www.drbrownstein.com/ https://www.drbrownstein.com/blog/ https://www.drbrownstein.com/store/ References: The Statin Disaster Brownstein David How statistical deception created the appearance that statins are safe and effective in primary and secondary prevention of cardiovascular disease. Expert Review of Clinical Pharmacology, 2015; 8 (2): 201 DOI: 10.1586/17512433.2015.1012494

What You Need To Know About the Problems with Statin Drugs Statin is prescribed to people who have high cholesterols. The aim of this drug is to lower cholesterol and reduce the chances of experiencing heart related issues such as a heart attack. The statin drug blocks the substances that support the liver in making cholesterol. This makes the liver emit it through the blood. This drug is very effective, but it has very severe side effects. This makes it seem like the riskiness of taking the drug outweighs the benefits of statin drugs. Examples of statins include simvastatin (Zocor), rosuvastatin (Crestor), pravastatin (Pravachol), pitavastatin (Livalo), lovastatin (Altoprev), fluvastatin (Lescol), and atorvastatin (Lipitor). This read will outline some of the problems or side effects you are likely to experience when you ingest Statin. Side Effects of Statins If you start experiencing side effects of statin, ask your medical practitioner for advice on what to do. Do not just rush into pausing your medication. Muscle damage and pain- This is a very common complaint. The pain might resemble that of weakness, fatigue, or soreness in the muscles. It could be severe enough to affect how you go about your errands and work obligations or mild. It is possible but rare that statins can cause muscle pain and damage that is life threatening. This type of muscle damage is known as rhabdomyolysis. It is severe because it affects the kidney, liver, and muscles. It could even cause death. This can happen when you ingest high doses of statins or you take it with a combination of other drugs. Liver damage- Statins affect the enzyme levels that cause liver inflammation. If the enzyme levels are very high, seek medical attention immediately you start experiencing the following symptoms yellow eye or skin,  dark-colored urine, upper abdominal pain, loss of appetite, unusual weakness or fatigue. Neurological issues- Some people experience confusion and develop memory loss when they take some statins. The good thing is that this side effect reverses once the person discontinues their medication. This means that it is not permanent damage. Take note that this side effect is very rare. Even though it does affect the neurological functions of some people, it would be beneficial to note that it also helps people who suffer from dementia. Thus, the effects are different. Just because your friend is experiencing memory loss, it does not mean that you will. Make sure you consult your doctor before you stop taking your medication. The doctor might prescribe other statins that do not have that effect on your neurological functions.

I continue to be horrified by guidelines issued by the American Heart Association and American College of Cardiology, which speak of giving statin drugs to healthy people. Meanwhile, draft recommendations from the US Preventive Task Force have issued new directives claiming that healthy people should be taking statin drugs as a “preventative against possible future illness.” Their main plan is to see one third of all adults in the United States are put on statin drugs—44% of all men and 22% of all women—even if none of these people have ever had a previous heart attack or stroke. Statins are the most widely prescribed drugs on the market. One in four Americans over 45 are already on statins, despite more than 900 studies reporting dangerous side effects from these drugs. These range from heightened risks of cancer and diabetes to sexual problems, neuropathy, and liver dysfunction, as well as immune system suppression, and even a higher risk of cataracts. In Britain too, statins are the most commonly prescribed drugs, costing the NMS £450 million a year. Now 40% of adults (175 million people) are being advised to take the drug. If the new directives are put into practice by the UK medical establishment—as they are likely to be—the numbers of men and women being prescribed statins could well become legion. What are statins anyway? Statins are a group of drugs prescribed to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol in the liver. Statins have many different names, such as Lipitor, Lescol, Mevacor, Altocor, and Zocor. These drugs are prescribed on the assumption that they will lower the risks of cardiovascular events and strokes. The new directives assert that, if given to healthy people, they could help protect the population from heart attacks and strokes at some time in the future. Happily, a growing number of cardiologists are strongly opposed to the new directives. What’s the problem with statins? Plenty: They deplete your body of CoQ10, which is essential for every cell in your body, and ubiquinol. Both CoQ10 and ubiquinol keep the so-called bad cholesterol from doing harm to your body. However, very few mainstream doctors are ever aware of these dangers. One exception is cardiologist Steven Sinatra, founder of the New England Heart Center. Sinatra recommends that anyone taking statins should take between 100 and 200 mg of CoQ10 or ubiquinol each day as protection. Statins lower Vitamin K2 in the body. This puts you at risk of deficiency of this vitamin, which contributes to chronic diseases, such as osteoporosis, cancer, and brain disease. Long-term statin use—10 years or so—has been shown to increase your risk of diabetes, neurogenerative diseases, musculoskeletal problems, and even cataracts. Dr. Eric Topol, highly respected cardiologist and Professor of Genomics at Scripps Research Institute in California, wrote an excellent article for The New York Times Opinion Page in which he warns: “We’re overdosing on cholesterol-lowering statins.” Topol is especially concerned about the sharp increase in the prevalence of Type 2 Diabetes that is occurring in people using them. He writes: “Statins have been available since the 1980s but their risk of inducing diabetes did not surface for nearly 20 years. When all the data available from multiple studies was pooled in 2010 for more than 91,000 patients randomly assigned to be treated with a statin or a sugar pill (placebo), the risk of developing diabetes with any statin was one in every 255 patients treated. But this figure is misleading since it includes weaker statins like Pravachol and Mevacor—which were introduced earlier and do not carry any clear-cut risk. It is only with the more potent statins—Zocor (now known as simvastatin), Lipitor (atorvastatin), and Crestor (rosuvastatin)—particularly at higher doses—that the risk of diabetes shows up. The cause and effect was unequivocal because the multiple large trials of the more potent statins had a consistent excess of diabetes.” Meanwhile, a recent study by Jean A. McDougall and her colleagues in the Journal of Cancer Epidemiology, Biomarkers & Prevention reveals that long-term use of statins increases the risk of both lobular and ductal breast cancer in women between 55 and 74. I am no doctor, but what I have learned during my more than forty years of writing and broadcasting on health is this: When a body is restored to healthy functioning naturally, the need for medication is either dramatically reduced or, more often than not, eliminated altogether. Statins, like most pharmaceuticals, only mask symptoms—they do not heal. Only nature can heal from within. My advice to anyone thinking of accepting the new directives is this: Before you agree to take statins, research the implications of doing so. Learn as much as you can about statin drugs. There are excellent natural alternatives, such as inexpensive dietary changes. So, if your doctor wants to prescribe statins for you, you can be sure you have done your homework. Then you’ll know yourself if these drugs are appropriate for you. Chances are they are not. Here are a few recommendations for where to start your research: U-T San Diego “Doctors assail new guidelines for statins: 18 November, 2013 Cancer Epidemiology, Biomarkers & Prevention; Published Online First July 5, 2013; doi: 10.1158/1055-9965.EPI-13-0414 http://www.greenmedinfo.com/toxic-ingredient/statin-drugs. This is an excellent compilation of dangers from statin drugs, with links to abstracts. www.ncbi.nlm.nih.gov/pubmed/24052188 Association of statin use with cataracts: a propensity score-matched analysis. This is a good source of information on the use of statins for the elderly. A. Sultan and N. Hynes, "The Ugly Side of Statins. Systemic Appraisal of the Contemporary Un-Known Unknowns," Open Journal of Endocrine and Metabolic Diseases, Vol. 3 No. 3, 2013, pp. 179-185. doi: 10.4236/ojemd.2013.33025.

I continue to be horrified by guidelines issued by the American Heart Association and American College of Cardiology, which speak of giving statin drugs to healthy people. Meanwhile, draft recommendations from the US Preventive Task Force have issued new directives claiming that healthy people should be taking statin drugs as a “preventative against possible future illness.” Their main plan is to see one third of all adults in the United States are put on statin drugs—44% of all men and 22% of all women—even if none of these people have ever had a previous heart attack or stroke. Statins are the most widely prescribed drugs on the market. One in four Americans over 45 are already on statins, despite more than 900 studies reporting dangerous side effects from these drugs. These range from heightened risks of cancer and diabetes to sexual problems, neuropathy, and liver dysfunction, as well as immune system suppression, and even a higher risk of cataracts. In Britain too, statins are the most commonly prescribed drugs, costing the NMS £450 million a year. Now 40% of adults (175 million people) are being advised to take the drug. If the new directives are put into practice by the UK medical establishment—as they are likely to be—the numbers of men and women being prescribed statins could well become legion. What are statins anyway? Statins are a group of drugs prescribed to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol in the liver. Statins have many different names, such as Lipitor, Lescol, Mevacor, Altocor, and Zocor. These drugs are prescribed on the assumption that they will lower the risks of cardiovascular events and strokes. The new directives assert that, if given to healthy people, they could help protect the population from heart attacks and strokes at some time in the future. Happily, a growing number of cardiologists are strongly opposed to the new directives. What’s the problem with statins? Plenty: They deplete your body of CoQ10, which is essential for every cell in your body, and ubiquinol. Both CoQ10 and ubiquinol keep the so-called bad cholesterol from doing harm to your body. However, very few mainstream doctors are ever aware of these dangers. One exception is cardiologist Steven Sinatra, founder of the New England Heart Center. Sinatra recommends that anyone taking statins should take between 100 and 200 mg of CoQ10 or ubiquinol each day as protection. Statins lower Vitamin K2 in the body. This puts you at risk of deficiency of this vitamin, which contributes to chronic diseases, such as osteoporosis, cancer, and brain disease. Long-term statin use—10 years or so—has been shown to increase your risk of diabetes, neurogenerative diseases, musculoskeletal problems, and even cataracts. Dr. Eric Topol, highly respected cardiologist and Professor of Genomics at Scripps Research Institute in California, wrote an excellent article for The New York Times Opinion Page in which he warns: “We’re overdosing on cholesterol-lowering statins.” Topol is especially concerned about the sharp increase in the prevalence of Type 2 Diabetes that is occurring in people using them. He writes: “Statins have been available since the 1980s but their risk of inducing diabetes did not surface for nearly 20 years. When all the data available from multiple studies was pooled in 2010 for more than 91,000 patients randomly assigned to be treated with a statin or a sugar pill (placebo), the risk of developing diabetes with any statin was one in every 255 patients treated. But this figure is misleading since it includes weaker statins like Pravachol and Mevacor—which were introduced earlier and do not carry any clear-cut risk. It is only with the more potent statins—Zocor (now known as simvastatin), Lipitor (atorvastatin), and Crestor (rosuvastatin)—particularly at higher doses—that the risk of diabetes shows up. The cause and effect was unequivocal because the multiple large trials of the more potent statins had a consistent excess of diabetes.” Meanwhile, a recent study by Jean A. McDougall and her colleagues in the Journal of Cancer Epidemiology, Biomarkers & Prevention reveals that long-term use of statins increases the risk of both lobular and ductal breast cancer in women between 55 and 74. I am no doctor, but what I have learned during my more than forty years of writing and broadcasting on health is this: When a body is restored to healthy functioning naturally, the need for medication is either dramatically reduced or, more often than not, eliminated altogether. Statins, like most pharmaceuticals, only mask symptoms—they do not heal. Only nature can heal from within. My advice to anyone thinking of accepting the new directives is this: Before you agree to take statins, research the implications of doing so. Learn as much as you can about statin drugs. There are excellent natural alternatives, such as inexpensive dietary changes. So, if your doctor wants to prescribe statins for you, you can be sure you have done your homework. Then you’ll know yourself if these drugs are appropriate for you. Chances are they are not. Here are a few recommendations for where to start your research: U-T San Diego “Doctors assail new guidelines for statins: 18 November, 2013 Cancer Epidemiology, Biomarkers & Prevention; Published Online First July 5, 2013; doi: 10.1158/1055-9965.EPI-13-0414 http://www.greenmedinfo.com/toxic-ingredient/statin-drugs. This is an excellent compilation of dangers from statin drugs, with links to abstracts. www.ncbi.nlm.nih.gov/pubmed/24052188 Association of statin use with cataracts: a propensity score-matched analysis. This is a good source of information on the use of statins for the elderly. A. Sultan and N. Hynes, "The Ugly Side of Statins. Systemic Appraisal of the Contemporary Un-Known Unknowns," Open Journal of Endocrine and Metabolic Diseases, Vol. 3 No. 3, 2013, pp. 179-185. doi: 10.4236/ojemd.2013.33025.

If you are taking a cholesterol-lowering statin drug such as Lipitor, Zocor, Crestor or Pravachol and want to add to the body what is being robbed that the heart must have, then we have important news to share with you today. WE HAVE ALL BEEN LED TO believe that cholesterol is bad and that lowering it is good. Because of extensive pharmaceutical marketing to both doctors and patients, so we think that using statin drugs is proven to work to lower the risk of heart attacks and death. But on what scientific evidence is this based, what does that evidence really show? Roger Williams a theologian; once said something that is very applicable to how we commonly view the benefits of statins. “There are liars, damn liars, and statisticians.” Tune in this Wednesday evening September 10, at 7:PM to hear the rest of the story.

Have you noticed that when a person starts taking medications, more medications are prescribed to treat the side effects caused by the original medications. Many of these side effects are caused by Medications That Cause Nutritional Deficiencies that these drugs create. In the end, these medications can really add up.   Many prescription drugs on the market cause nutrient deficiencies. For example, a common medication like the statins (Pravachol, Lipitor and Crestor), which are used to treat high cholesterol, reduces CoQ10 in the body. CoQ10 is the most abundant antioxidant in the body. It is very important for muscle function. A symptom of CoQ10 deficiency is muscle aches, like thigh or trunk pain. Patients cannot feel the depletion of CoQ10 in the heart muscle, however. Absolute CoQ10 depletion can cause heart failure and death.   Another example would be diuretics that patients are prescribed for hypertension. These medications get rid of water as well as the minerals Magnesium and Zinc. When men are deficient in Magnesium and Zinc, they are unable to make Testosterone.   So, when you look at the complex biochemical cascade, many cofactors are necessary for these pathways to run properly in the body. When one or many or lacking, the results can cause a decrease in the hormones produced. See how a simple deficiency in Magnesium or Zinc caused by diuretics can cause another problem such as low Testosterone. The male then experiences the side effects of low Testosterone, which are plentiful.   If a medication causes low Magnesium, this mineral has 300-400 functions in the body. Low Magnesium can lead to an enormous amount of problems in the body. Physicians who specialize in Functional and Regenerative Medicine or Anti-Aging can test for Magnesium and there are high-quality Magnesium supplements available if you are deficient. You can look at Triton Nutrition and read the article on Magnesium to find the best form of chelated Magnesium supplement for maximum absorption and look at their online store to view their product Mag Powersorb. Low Magnesium leads to poor blood sugar control, poor bowel function (constipation), poor blood pressure control, muscle cramps and spasms, and insomnia or poor sleep. One deficiency leads to a multitude of problems.   Proton Pump Inhibitors such as Prilosec, Nexium, and Prevacid are prescribed to reduce the amount of acid in the stomach. Without a certain amount of acid in the stomach, we don't absorb certain minerals like Calcium. So, it is common to see a person who started taking Proton Pump Inhibitors (PPI) end up with Calcium depletion and weak bones. Actually, Functional Medicine Physicians believe that the treatment with acid is what is needed instead so that the lower esophagael sphincter will tighten and close off after it is signaled by a proper amount of acid in the stomach.   Your micronutrient levels can be tested. It is necessary before you start bio-identical hormone replacement therapy to supplement any deficiencies before you start on your therapy for you to receive optimal results. Also, hormone replacement therapy can cause nutrient deficiencies so you must monitor your micronutrients so they can be replaced sufficiently. The most common deficiencies that require repletion are Folic Acid, Magnesium, and Vitamin B12 after you start your therapy. These are all necessary cofactors.   For more information, Dr. Pamela Wartian Smith, a physician with American Academy of Anti-Aging, wrote an excellent book called Vitamins, Minerals, Herbs and More. There you will find specific protocols on how to overcome specific nutrient depletions. Natural database has a chart on common medications that cause nutrient depletions.   A prescription drug depletion chart complements of Maryland Medical Center can be downloaded as well.   by Robert Seik, PharmD