Podcasts about hdl

Optimiza tu LDL Colesterol e interpreta tu analítica o las de tus pacientes hoy, sin fármacos, aplicando estrategias nutricionales y suplementos clave con dosis y ciencia. Accede aquí:https://philhugo.com/producto/ldl-colesterol/  ¡Te espero dentro!Los suplementos be levels mencionados que formulo personalmente: Tu código de descuento: INTERGALACTICOBerberina: https://shop.belevels.com/products/berberine?sca_ref=745165.uf0cpcacla Omega 3: https://belevels.com/products/omega3?sca_ref=745165.uf0cpcaclaTriple Magnesio: https://belevels.com/products/magnesium?variant=47417739379012.uf0cpcacla Dosis y los demás explicados en el curso de Control Absoluto del LDL Colesterol.¿Sigues una dieta cetogénica estricta y tu LDL se ha disparado a niveles que asustarían a cualquier médico? No estás solo. En este episodio, desentrañamos la fisiología del Lean Mass Hyperresponder (LMHR): un perfil metabólico donde el colesterol LDL se eleva no por enfermedad, sino por eficiencia energética. Aprende cómo tu hígado, en ausencia de glucosa, convierte grasa en combustible a través de VLDL y LDL. Descubre por qué un LDL de 300 mg/dL puede ser normal si tu HDL está alto, tus triglicéridos bajos y tu inflamación es cero. Estudio a estudio, desmonto los miedos injustificados y propone estrategias clínicas reales para modular tu LDL si es necesario, desde el aumento de carbohidratos limpios hasta la optimización tiroidea y muscular. Este episodio no es para quien se conforma con los rangos de laboratorio estándar. Es para quien quiere entender su cuerpo desde la lógica metabólica y tomar decisiones con ciencia, no con miedo.ReferenciasApoB es biomarcador y posible diana terapéutica cardiovascular. Behbodikhah, Jennifer et al. “Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target.” Metabolites vol. 11,10 690. 8 Oct. 2021LDL sube mucho en "lean mass hyper-responders" con dieta baja en carbohidratos. Norwitz, Nicholas G et al. “Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence for a "Lean Mass Hyper-Responder" Phenotype.” Current developments in nutrition vol. 6,1 nzab144. 30 Nov. 2021Marcadores tiroideos y composición corporal predicen cambios en LDL con dieta cetogénica. Cooper, Isabella D et al. “Thyroid markers and body composition predict LDL-cholesterol change in lean healthy women on a ketogenic diet: experimental support for the lipid energy model.” Frontiers in endocrinology vol. 14 1326768. 21 Dec. 2023Omega-3 mejora dislipidemia en relación dosis-respuesta. Wang, Tianjiao et al. “Association Between Omega-3 Fatty Acid Intake and Dyslipidemia: A Continuous Dose-Response Meta-Analysis of Randomized Controlled Trials.” Journal of the American Heart Association vol. 12,11 (2023): e029512.Omega-3 de prescripción tiene efectos lipídicos beneficiosos. Bays, Harold E et al. “Prescription omega-3 fatty acids and their lipid effects: physiologic mechanisms of action and clinical implications.” Expert review of cardiovascular therapy vol. 6,3 (2008): 391-409La berberina reduce lípidos, sola o combinada. Koppen, Laura M et al. “Efficacy of Berberine Alone and in Combination for the Treatment of Hyperlipidemia: A Systematic Review.” Journal of evidence-based complementary & alternative medicine vol. 22,4 (2017): 956-968.Niacina baja lipoproteína(a) según fenotipo de apo(a). Artemeva, N V et al. “Lowering of lipoprotein(a) level under niacin treatment is dependent on apolipoprotein(a) phenotype.” Atherosclerosis. Supplements vol. 18 (2015): 53-8

Story at-a-glance Dragon fruit delivers antioxidant protection, gut support, and metabolic benefits, making it an easy way to upgrade your fruit intake Research shows that 100 grams of dragon fruit, about 1/2 cup, daily lowers LDL cholesterol by up to 69%, raises HDL by over 60%, and reduces triglycerides within weeks Bioactive compounds in the flesh, seeds, and even peel help fight inflammation, protect your liver, and feed beneficial gut bacteria like Akkermansia and Lactobacillus Dragon fruit's natural sugars provide steady energy without blood sugar crashes, making it an ideal pre-workout snack or midday pick-me-up It's especially helpful for pregnancy, digestive sluggishness, and skin repair, thanks to its folate content, natural hydration, and collagen-boosting vitamin C

Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I'm a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients. Dr. Warrick Bishop, a cardiologist and CEO of the Healthy Heart Network, discusses the importance of understanding cholesterol in his podcast. He explains that cholesterol is crucial for cell membranes, hormone formation, and vitamin transport, and that LDL and HDL are transport vehicles for cholesterol. Dr. Bishop clarifies that cholesterol's impact on heart health is complex, as high LDL doesn't always indicate artery plaque, and low cholesterol doesn't always mean healthy arteries. He emphasizes the importance of coronary artery calcium scoring, particle numbers, and other factors in assessing artery health and predicting risk. For secondary prevention, lowering cholesterol is crucial, while primary prevention requires a personalized approach, considering individual risk factors and imaging.

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A new study has suggested that individuals consuming whole cheese, experienced lower levels of LDL cholesterol compared to individuals who consumed deconstructed cheese which affects the cheese matrix (the network of proteins of fat and minerals made during the cheese manufaturing process) and alters the bioavailability of beneficial fats in the cheese. There may also be a difference between how men and women respond to cheese consumption. This study also challenges the historical view that all saturated fat consumption is harmful. In this episode I discuss what cholesterol is, HDL , LDL and the link between high cholesterol and cardiac health. The dangers of high carbohyrate foods : https://www.youtube.com/playlist?list=PLSKlhyEANfi8hZFoFoJun_lLhULcYg5JWWeightloss series : https://www.youtube.com/playlist?list=PLSKlhyEANfi-pO3W2hejnDUsgMQ9GPvpZThe health benefits fo exercise : https://www.youtube.com/playlist?list=PLSKlhyEANfi_vM1nbpcV-PlvWjSZ872ECOrder Happy Habits for Mind and Body Audiobook: https://amzn.to/3KeQmGrOrder Kindle copy of Happy Habits for Mind and Body : https://amzn.to/4c9T38fOrder US paperback of Happy Habits for Mind and Body : https://amzn.to/4bxczeTOrder UK paperback of Happy Habits for Mind and Body : https://rb.gy/jtfea5Listen to all previous podcast episodes of the Happy Habit Podcast via these podcast platforms :Apple Podcasts https://podcasts.apple.com/ie/podcast/happy-habit-podcastAmazon https://www.amazon.com/Happy-Habit-Podcast/dp/B08K5887J8Amazon music : https://music.amazon.com/podcasts/670836c2-ea4c-4a23-a67d-a54dd804ef61/happy-habit-podcastSpotify https://https://open.spotify.com/show/2VKIhQK6mYTzLCO8haUoRdFollow the Happy Habit Podcast Website: https://happyhabitpodcast.wordpress.com/Music used is Purple planet Music crediit goes to them

In this episode of Proven Health Alternatives, I sit down with Dr. Darren Schmidt to explore one of the most promising tools in functional medicine today: the MVX Plus test. Launched in 2025, this next-gen blood panel goes far beyond standard labs—offering a deeper lens into chronic inflammation, mitochondrial dysfunction, nutrient deficiencies, and more. Dr. Schmidt breaks down the six core markers—from GlycA to citrate to branched-chain amino acids—and explains how they uncover hidden vulnerabilities affecting your healthspan. We also dive into practical insights, like the importance of vitamin B1, the dangers of ultra-processed diets, and how MVX can detect issues even when standard tests look “normal.” If you're serious about optimizing longevity, identifying root causes, or catching problems before they escalate—this episode is packed with the clinical gold you've been waiting for. Key Takeaways: Understanding MVX Plus: MVX Plus measures pivotal factors like Glyc A, small HDL particles, and branched-chain amino acids to offer a nuanced assessment of chronic diseases and longevity. Importance of B1: Dr. Schmidt underscores the critical role of Vitamin B1 in managing metabolic health and shares his dramatic recovery story from a gas leak-induced health crisis. Seven-Step Program: This comprehensive framework targets diet, energy, and detoxification to systematically improve health outcomes as indicated by MVX Plus results. Clinical Implications: Real-world examples emphasize how timely intervention based on MVX test results can dramatically affect a patient's health trajectory. Holistic Health: The episode advocates for a return to holistic practices and the understated value of nutrition, particularly protein-rich diets, in combating malnutrition. More About Dr. Darren Schmidt: Dr. Darren Schmidt, D.C. is the founder of the Nutritional Healing Center of Ann Arbor, the largest non-insurance nutrition clinic in the U.S. His 7-Step Blueprint to Optimal Health and MVX Plus blood test position him as a leader in root-cause foundational nutrition. He began practicing in 1997 and was early to adopt low-carb, keto, and carnivore—while always focusing on detox, nourishment, and restoring function. In 2005, he stopped accepting insurance to ensure clinical results weren't compromised. He has delivered over 100 seminars to 10,000+ healthcare professionals and continues to advance natural solutions for chronic disease. Website Instagram How MVX Can Help YouTube Connect with me! Website Instagram Facebook YouTube This episode is sponsored by Professional Co-op®, where clinicians gain exceptional access to industry-leading lab services without the hefty price tag—since 2001, they've been redefining what efficient, patient-focused support looks like. Imagine no hidden fees, no minimums, and only paying for completed tests. Experience lab services that not only meet but also exceed your expectations. Join the co-op trusted by countless licensed clinicians nationwide. Visit www.professionalco-op.com to learn more!

Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I'm a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients. In this podcast, Dr. Warrick Bishop, a cardiologist and CEO of the Healthy Heart Network, discusses key health topics related to heart disease, which significantly impacts Australia. He emphasizes the importance of understanding blood pressure, weight, and cholesterol to improve health outcomes. The discussion highlights high-density lipoprotein (HDL), often labeled as "good cholesterol," noting that while higher levels are generally protective, some individuals with genetically high HDL may actually face increased heart disease risk if the HDL is not functional.

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All Things TechIE Podcast - Episode 117  speaking with Rob Abbott from Nureva's new HDX SeriesNureva Inc., an innovator in advanced audio solutions, announces the Nureva® HDX pro audio series. Each HDX configuration is a complete and flexible solution designed to meet the full range of in-room audio and remote conferencing requirements for higher education classrooms, corporate training rooms, flex spaces and large meeting rooms up to 60′ x 40′ (18.3 x 12.2 m). Building off the success of Nureva's HDL pro series systems for audio conferencing, the HDX series is a direct response to the mounting costs and complexities faced by IT managers who need to support a growing set of in-room audio requirements beyond full-room microphone pickup. HDX systems come with the choice of two or four wall-mounted audio bars and one or two optional microphone pods for Adaptive Voice Lift and enhanced microphone coverage. The system hub has single-cable AV-over-IP connectivity. These components are designed to be simple to install and set up, and therefore highly scalable, and they can be configured in varying combinations depending on the room size and in-room audio requirements. HDX systems deliver full-room speaker coverage that combines distributed audio with full-range loudspeakers for exceptional in-room sound.

Story at-a-glance A study found that vegetarians who ate plant-based fake meat are 42% more likely to experience depression than those who don't, even when factors like age, BMI, and lifestyle are taken into account Eating fake meat leads to higher levels of C-reactive protein (CRP), a marker of systemic inflammation linked to chronic diseases like heart disease, diabetes, and autoimmune disorders Triglycerides were elevated and HDL cholesterol was lower in those eating fake meat, increasing their long-term risk for cardiovascular disease The body reacts to fake meat not because of its nutrients, but because of ultraprocessed ingredients and additives that disrupt immune signaling and metabolic function Even when blood nutrient levels appear normal, the deeper immune system activity reveals that fake meat is pushing your body toward inflammation and oxidative stress

PhD in synthetic chemistry, the Product Formulator for Supplement Needs, and fitness industry renowned Pharmacologist for his no-nonsense approach in bodybuildingThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder:[ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]https://transcendcompany.com/patient-intake-form/?ls=Nyle+NaygaWatch it: https://www.youtube.com/watch?v=6Ihq4tIzyS8&t=5618sRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.com2:19 Bodybuilding Pharmacology and Dosing4:53 Brain Health and Long-Term Risks7:29 Muscle Building and Genetic Factors10:03 Cholesterol and LDL Impacts12:14 Podcast Setup and Equipment Upgrades14:34 Hair Transplant Journey24:23 Hair Loss Causes and Treatments34:59 Post-Transplant Recovery and Rebound39:31 Epigenetics and Muscle Memory43:04 Ethical Questions on Genetic Enhancement45:40 Enhanced Games Debate50:09 Dosing Challenges in Enhanced Sports52:32 Data Collection and Human Experimentation55:16 Genetic Variance and Elite Athletes59:04 Neurodegeneration and PEDs1:07:08 Oxidative Stress in Bodybuilding1:09:37 Sleep and Brain Detox1:18:01 Nutrition for Oxidative Stress1:19:02 Melatonin as an Antioxidant1:21:13 Melatonin Dosing and Effects1:24:51 Melatonin and Sleep Support Supplements1:28:22 Magnesium and Sleep Health1:31:23 Sleep Apnea and Neural Health1:36:30 Frequent Urination at Night1:46:33 Overheating During Sleep1:59:14 Wrapping Up Oxidative Stress2:00:33 Neuron Loss and Neurotransmitters2:02:04 Boosting Brain Health with BDNF2:04:08 Peptides for Neural Growth2:09:14 Oxidative Stress and Supplements2:12:34 Neuroprotection Strategies2:19:56 EMF and Environmental Stressors2:22:12 Mitochondrial Dysfunction and Aging2:24:55 Balancing Oxidative Stress2:28:32 Steroids and Muscle Growth Rates2:38:54 HDL and LDL Control Ancillaries2:41:34 Statins and LDL Oxidation2:47:36 Antioxidants and Plaque Formation2:54:10 Balancing Cholesterol Levels2:58:35 CT Scans for Heart Health3:03:54 Heart Health Supplements3:06:48 Mitochondrial Stack Under 303:16:27 Balanced Diet in Prep3:20:24 Omega-3 and Fish Oil Quality3:23:36 Podcast Wrap-Up

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3012: Dr. Neal breaks down the role of genetics in cholesterol levels and explains how even those with a family history of heart disease can benefit from targeted lifestyle changes. From diet tweaks to exercise strategies, his practical tips empower listeners to take control of their heart health, no matter their DNA. Quotes to ponder: "HDL actually helps the body clear LDL from the arteries, which is why it's good." "One of the most effective ways to lower blood cholesterol and blood pressure quickly is weight loss." "Fiber is so helpful because it helps bind to cholesterol and helps the body get rid of it." Episode references: Omega-3 Fatty Acids (NIH Office of Dietary Supplements): https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer USDA FoodData Central: https://fdc.nal.usda.gov/ National Heart, Lung, and Blood Institute: https://www.nhlbi.nih.gov Learn more about your ad choices. Visit megaphone.fm/adchoices

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3012: Dr. Neal breaks down the role of genetics in cholesterol levels and explains how even those with a family history of heart disease can benefit from targeted lifestyle changes. From diet tweaks to exercise strategies, his practical tips empower listeners to take control of their heart health, no matter their DNA. Quotes to ponder: "HDL actually helps the body clear LDL from the arteries, which is why it's good." "One of the most effective ways to lower blood cholesterol and blood pressure quickly is weight loss." "Fiber is so helpful because it helps bind to cholesterol and helps the body get rid of it." Episode references: Omega-3 Fatty Acids (NIH Office of Dietary Supplements): https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer USDA FoodData Central: https://fdc.nal.usda.gov/ National Heart, Lung, and Blood Institute: https://www.nhlbi.nih.gov Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, Dr. Carolyn Moyers breaks down the latest original research from the April 2025 issue of Obstetrics & Gynecology, focusing on the long-term cardiovascular biomarker changes in women who participated in the Women's Health Initiative Hormone Therapy Trials. What does this mean for real-life patients considering hormone therapy? Are there age-related risks? What's the deal with triglycerides?Dr. Moyers explores the clinical relevance of these findings, limitations of the data, and the questions that still remain—offering an evidence-based, patient-centered perspective for women navigating menopause and their heart health.

Too busy to read the Lens? Listen to our weekly summary here! In this week's episode we discuss:Both high and low levels of HDL were associated with increased risk of AMD, though the mechanism for this remains unclear.A majority of ophthalmic subspecialists practice in urban areas, and this trend has increased over the last decade.Study compares 5 modern toric IOL formulas for cataract patients with astigmatism.Systemic GLP-1 inhibitor treatment was found to reduce size and leakage of CNVM lesions in mouse models.

Send us a textDr. Ankur Verma, an emergency medicine specialist from New Delhi and host of The DESI EM Project podcast, shares his compelling journey from a carb-heavy Indian diet to embracing a carnivore lifestyle after facing severe metabolic health issues. By adopting a meat-based diet, he reversed his own metabolic syndrome and witnessed remarkable health improvements in others, including his uncle's reversal of 25 years of diabetes. Dr. Verma challenges conventional nutritional wisdom by emphasizing the importance of biomarkers like triglyceride-to-HDL ratio and homocysteine levels over traditional cholesterol metrics. Through his podcast, he delves into topics such as emergency medicine, nutrition, and the influence of pharmaceutical interests on medical education, advocating for a root-cause approach to health. Follow his insights on Instagram @thecarnivore.epConnect with Ankur:@thecarnivore.epDesi EM Project - Spotify Desi EM Project - Apple  Support the showPRIMAL FOUNDATIONS PODCAST-Instagram: @Tony_PrimalFoundationsWebsite: Primalfoundations.com The Strength Kollective: Download Kettlebell Programs (Click Here)Book a free 30 minutes consultation (Click Here)

Te explico todo sobre la famosa "triada cetogénica": colesterol LDL elevado, triglicéridos bajos y HDL alto, un patrón común en quienes siguen una nutrición cetogénica bien ejecutada. Detallo cómo esta triada, lejos de ser peligrosa, puede reflejar un estado metabólicamente saludable, especialmente cuando se acompaña de un bajo porcentaje de grasa corporal, buenos hábitos y una dieta rica en omega-3 y verduras. También hablo de los errores más comunes en la interpretación de analíticas y el uso excesivo de estatinas sin evaluar el contexto clínico del paciente.

Story at-a-glance Cholesterol is essential for hormone production, brain function, and cell health, and about 80% of it is made by your body — not consumed in food. High triglycerides, not total cholesterol, pose a stronger risk for heart attack — raising risk by 80% — making triglyceride-to-HDL ratio a better heart disease predictor Newer science shows chronic inflammation — not LDL alone — may be the real cause of plaque buildup in arteries, shifting focus to markers like ApoB and CRP Natural options like garlic, artichoke, bergamot, plant sterols, green tea, and oats have been shown in clinical studies to lower LDL cholesterol and improve heart markers Red yeast rice can lower LDL by up to 33%, but it contains a statin-like compound with the same side effects and potential kidney toxins like citrinin Lifestyle changes like cutting sugar, walking daily, and sleeping well can activate the Pareto Principle — where 20% of effort yields 80% of results in lowering cholesterol. Exercise improves five key metabolic biomarkers — glucose, HDL, triglycerides, blood pressure, and waist size — each linked to long-term cardiovascular health

Welcome back to our weekend Cabral HouseCall shows!   This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!   Check out today's questions:     Kellie: Hi Dr. Cabral! I have been with your program for almost 6 months now. I have completed the Vit-Tox tests and have gone through the FM Detox twice and now going through the CBO Protocol. I just turned 38 years old and I feel like my joints are of an 80 year old. I have played soccer since age 5 and still play on a competitive coed league to this day. I have played many other team/contact sports in the past. I have had past ankle, knee, and hip injuries due to sports and I do see possible knee and hip replacements in my future. When I do my daily workouts or go up/down stairs my ankles, knees, hips, and back crack or pop so easily and so much. I don't see glucosamine chondroitin as a supplement in your shop. Are there any suggestions you may have to keep my joints healthier? Thank you!!              Jon: Hey Dr Cabral, looking for advice and i feel like there's a population that struggles with this same topic. My Dr is recommending a statin due to my high LDL-C of 230. My LDL has gone up after cleaning up my diet in the last 7 months however ALL of my markers tested for have improved. Triglycerides have gone from over 200 to 100, HDL is up to 60, VLDL has dropped from 30 to 15, A1C is 5.2, blood pressure is normal for the first time ever, and so onr. My personal opinion is that i'm healthier than ever and i can't imagine having to go on what seems like a lifetime drug due to one marker being off and i don't buy the story that LDL alone is a concern for me. Curious on your opinion here and if you think i have something to worry about. Thanks!!                                                                                                                            Annette: I've been diagnosed with nephrocalcinosis by conventional doctors who say the cause is genetic. I have adjusted my diet to low sodium, low oxalate foods. The doctors say my next step is to try to get on the kidney transplant list before I need dialysis. I take potassium citrate and a calcitriol. Is there anything I can do to improve my kidney function?                                                                                                  Summer: Hi Dr. Cabral! I heard you say that it's best to replace aluminum cookware, but not necessary, and instead to use parchment paper as a barrier. Doesn't the aluminum off gas when heated? How does parchment paper prevent the aluminum from getting into the food? Thanks! By the way, to all my fellow listeners: please contact your state representatives and let them know you do not consent to geo-engineering in your skies. Several states have now banned it. We could all live healthier lives if we could work toward eliminating toxins and heavy metals including aluminum that are regularly being sprayed into our air.                                                                                                                                                Ann: Thank you Dr Cabral- you are changing SO many lives - thank you for all of your wisdom and teachings:) I have a question about Magnesium. My cortisol was high at my last lab test, and I took Full Spectrum magnesium for 12 weeks, and now I take Cal Mag daily. I also understand that I can take Calming Magnesium and CBD at night to help with sleep.I don't want to take too much for too long for my body, but I still think I need the help for my cortisol levels/ sleep. What combination of the above do you recommend? Is there a length of time that is too long to be on Full Spectrum Magnesium? PS. I do the 3-2-1 protocol, take Adrenal Soothe and will be repeating my big 5 this fall. Thank you again!           Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!      - - - Show Notes and Resources: StephenCabral.com/3396 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Send us a textDr. Adrian Soto-Mota is a returning guest on our show! Be sure to check out episode 138 of Boundles Body Radio, which was part of a special series we did, featuring Dr. Nick Norwitz as the guest host!We also hosted Dr. Soto-Mota on episode 340, episode 419, and episode 599 of our show!Dr. Soto-Mota is a MD PhD & Specialist in Internal Medicine and Data Science researcher at the Unidad de Investigación de Emfermedades Metabólicas! Dr. Soto-Mota is passionate about studying low carbohydrate and ketogenic diets, and how they impact human metabolism.Dr. Soto-Mota earned his MD from the Universidad Nacional Autónoma de México, and earned his Ph.D. at Oxford. He has created many resources to help people successfully implement a low carbohydrate diet, and provides that help for both English and Spanish speaking individuals.He is the co-author of a 2022 paper titled The Lipid Energy Model: Reimagining Lipoprotein Function in the Context of Carbohydrate-Restricted Diets, and the co-author of the recent paper titled Plaque Begets Plaque, ApoB Does Not: Longitudinal Data From the KETO-CTA Trial- JACC Journal April 7, 2025, both of which were also co-authored by former guests Dr. Norwitz and Dave Feldman, who we hosted in episode 109 of Boundless Body Radio!Find Dr. Soto-Mota at-TW- @AdrianSotoMotaPlaque Begets Plaque, ApoB Does Not: Longitudinal Data From the KETO-CTA Trial- JACC Journal April 7, 2025Keto Cholesterol study SHOCKS scientific community | LMHRs & heart disease from the Nutrition Made Simple YouTube ChannelAnalyzing the KETO-CTA Study with Dr. Gil Carvalho 813 on Boundless Body Radio!Discussing Keto-CTA with Darius Sharpe with Dave Feldman and Darius SharpeFind Boundless Body at- myboundlessbody.com Book a session with us here!

It's another week of answering listener questions! In this episode, we discuss: If carb depletion before a big race has any ground  What it means if you have low HDL and what might be causing it Why you may be feeling nauseous mid-race and how to fix it Tips for avoiding all kinds of GI issues during training and racing Want to be featured on the show? Email us (written or an audio file!) at⁠ fuelforthesolepodcast@gmail.com⁠. This episode is fueled by ASICS and RNWY!Head over to⁠ ASICS.com⁠ and sign up for a OneASICS account. It's completely free and when you sign up you will receive 10% off your first purchase. You also gain access to exclusive colorways on ASICS.com, free standard shipping, special birthday month discounts and more.We've been using RNWY collagen, protein and pre workout and loving it. Head over to ⁠https://rnwy.life/⁠ and use code FEATHERS15 for 15% off your purchase. Disclaimer: This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

Overview   In this profoundly evocative episode of Higher Density Living, Jason Rigby welcomes Mary Reynolds Thompson, transformational coach and author of The Way of the Wild Soul Woman. Together, they traverse the barren landscapes and lush forests of the feminine psyche—inviting listeners into a mythic journey through the five sacred archetypes: Desert Woman, Forest Woman, Ocean/River Woman, Mountain Woman, and Grassland Woman. Mary masterfully unpacks how patriarchal systems fractured women's ancient bond with the Earth—and how reconnecting with nature's rhythms heals not only personal trauma but our planet itself. From honoring the barren stillness of solitude to embracing the spiraling growth of forest paths, this episode is a luminous guide for women and men alike to reclaim lost wisdom and embodied wholeness.   Whether you feel disoriented in a hyper-masculine world or curious about the power of archetypes, this is a compass pointing home to your primal, untamed self.   Timestamps 00:00 – Invitation to the Wild: Jason introduces Mary and the core premise of rewilding soul through Earth-based archetypes. 01:18 – What is the Wild Soul Story?: Mary defines a soul narrative rooted in Earth's psyche, inspired by Thomas Berry. 03:02 – Women & Earth: Shared Wounds: Discussion on patriarchal suppression of feminine and environmental wisdom. 08:15 – Desert Woman: The first archetype of solitude, silence, and shedding cultural roles. 13:12 – Forest Woman: Entering the spiral path of mystery, gestation, and inner transformation. 19:30 – Ocean & River Woman: Surrendering to emotion and trusting the current of longing. 26:06 – Mountain Woman: Manifesting bold purpose from inner knowing, unafraid of being seen. 29:47 – Grassland Woman: Re-entering the world with gifts and medicine, navigating return and reintegration.   Quotes “We are not separate from nature—we are nature.” – Mary Reynolds Thompson “Stillness is rebellion in a culture of overdoing.” – Mary Reynolds Thompson “Your soul's longing is sacred—it's the compass back to your wild truth.” – Jason Rigby   Resources   Internal Higher Density Living Website HDL Meditation Archives Previous HDL Episode: “Earth Is Our Ancestor” External Mary Reynolds Thompson's Website Book: The Way of the Wild Soul Woman Book: Reclaiming the Wild Soul Thomas Berry's The Dream of the Earth   Call to Action   Feeling disconnected from your essence? It's time to rewild your soul. Subscribe to HDL, share this episode with someone craving reconnection, and explore Mary's meditations and writings. The Earth remembers who you are—return to her.  

You've probably said it a hundred times: HDL is the "good" cholesterol, LDL is the "bad" cholesterol.But what if that explanation is oversimplified—and leading patients (and providers) to miss hidden risks?In this episode, I sit down with Dr. Josh Wageman—a Clinical Lipid Specialist, PhD researcher, and author of The Home Security System and the Lipid Neighborhood—to break down why the old-school lipid model isn't enough anymore, what a standard panel won't tell you, and how you can explain heart disease risk in a way that actually sticks with patients.If you've ever felt shaky explaining lipid panels, cardiovascular risk, or how diet ties in, this episode will give you a clearer framework—and practical tools you can use immediately with your patients.Resources:Buy the Book The Home Security System and the Lipid NeighborhoodConnect with Josh Episode 38 | Love Your HeartAny Questions? Send Me a MessageSupport the showConnect with Colleen:InstagramLinkedInSign up for my FREE Newsletter - Nutrition hot-topics delivered to your inbox each week. Disclaimer: This podcast is a collection of ideas, strategies, and opinions of the author(s). Its goal is to provide useful information on each of the topics shared within. It is not intended to provide medical, health, or professional consultation or to diagnosis-specific weight or feeding challenges. The author(s) advises the reader to always consult with appropriate health, medical, and professional consultants for support for individual children and family situations. The author(s) do not take responsibility for the personal or other risks, loss, or liability incurred as a direct or indirect consequence of the application or use of information provided. All opinions stated in this podcast are my own and do not reflect the opinions of my employer.

Your blueprint for navigating hormone shifts in your 30s, 40s, & 50s! In today's episode, integrative medicine physician Dr. Taz Bhatia talks about how to optimize hormones in your late 30s, what to do to support your liver and estrogen detoxification during perimenopause, and everything you need to know about starting hormone replacement therapy. We also answer your questions about lab work, signs of specific hormone imbalances, and unexplained midlife weight gain. This one has it all! Timestamps:[1:38] Noelle Intro[3:35] Welcome Dr. Taz [4:00] What's the latest research saying about women's health and hormones and what are you seeing actually work with your patients? [10:31] In your experience, what are the top things that women can do in their 30's to set themselves up for success in perimenopause?[14:40] Should we be looking at our numbers from testing and using that information to “optimize” them?[21:04] What's are the differences between the many hormonal shifts in our 30's?[26:47] What's a good repletion plan once we've been depleted due to stress, pregnancy or other things?[35:05] Do you think that women, as they enter perimenopause, should be regularly supporting the liver with herbs?[40:23] In perimenopause, what should I consider taking and what are the must dos? How do we know when it's time to start HRT?[42:12] Can you talk about the symptoms of low and high estrogen and progesterone? [44:35] How do you find a doctor that actually prescribes HRT? [45:25] I'm curious about when the right time is to get on HRT. Should I start it as a preventative measure or wait until I start experiencing symptoms? [46:39] What about HRT for people with the MTHFR mutation? [48:33] The change in body proportions have really played with my head. It's hard to feel healthy with an increase in midsection fat. How do I address this? [51:07] Is there any way to lower slightly elevated LDL cholesterol in perimenopause, even if HDL cholesterol is great? [51:30] Why do I feel terrible during ovulation? Episode Links:Hol+Follow Dr. Taz on InstagramThe Hormone Shift: Balance Your Body and Thrive Through Midlife and Menopause Super Woman Rx: Unlock the Secrets to Lasting Health, Your Perfect Weight, Energy, and Passion with Dr. Taz's Power Type PlansThe 21-Day Belly Fix: The Doctor-Designed Diet Plan for a Clean Gut and a Slimmer Waist Sponsors:Go to https://thisisneeded.com/  and use coupon code WELLFED for 20% off your first order.Go to boncharge.com/WELLFED and use coupon code WELLFED to save 15% off any order.Go to http://mdlogichealth.com/immuno and use coupon code WELLFED for 10% off.Go to wellminerals.us/chill and use code WELLFED to get 10% off your order.

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 2972: Dr. Neal Malik breaks down the cholesterol puzzle, explaining the difference between "good" and "bad" cholesterol, and why not all dietary fats, or even dietary cholesterol, are created equal. Learn the six simple lifestyle changes that can naturally improve your cholesterol profile and reduce long-term health risks. Quotes to ponder: "Cholesterol actually acts as a transporter in the body, the precious cargo in this case: fat." "Fiber is like HDL's sidekick, it helps the body get rid of that lousy or lethal LDL cholesterol." "High intensity activity in particular seems to help increase the happy or healthy HDL levels in the blood." Episode references: American Heart Association - Cholesterol: https://www.heart.org/en/health-topics/cholesterol Learn more about your ad choices. Visit megaphone.fm/adchoices

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 2972: Dr. Neal Malik breaks down the cholesterol puzzle, explaining the difference between "good" and "bad" cholesterol, and why not all dietary fats, or even dietary cholesterol, are created equal. Learn the six simple lifestyle changes that can naturally improve your cholesterol profile and reduce long-term health risks. Quotes to ponder: "Cholesterol actually acts as a transporter in the body, the precious cargo in this case: fat." "Fiber is like HDL's sidekick, it helps the body get rid of that lousy or lethal LDL cholesterol." "High intensity activity in particular seems to help increase the happy or healthy HDL levels in the blood." Episode references: American Heart Association - Cholesterol: https://www.heart.org/en/health-topics/cholesterol Learn more about your ad choices. Visit megaphone.fm/adchoices

Introduction   Welcome back to Higher Density Living! After a brief hiatus, hosts Alexander McCaig and Jason Rigby reunite in the studio, buzzing with life's latest revelations. Jason returns from a European adventure, while Alexander steps into fatherhood with the birth of his son, Gabrael. Together, they unpack the profound alchemy of parenting—blending raw spiritual awe with biological evolution. This episode, Part 1 of a two-part series, invites listeners to explore creation's edge, where innocence meets potential and exhaustion reveals divinity.   Hosts Bio Alexander McCaig: Co-host of HDL, a consciousness seeker and new father, sharing transformative insights from his journey into parenthood. Jason Rigby: Co-host, spiritual guide, and father, back from a European trip, weaving travel tales with deep reflections on the human condition.   Key Discussion Points 1. The Return and Life Updates Jason kicks off: “We're back! My gosh, it's been some time. You've really been gone—you've been busy.” Alexander: “I've been gone ‘cause I had a newborn recently—one of the most transformational experiences of my entire life.” Jason: “You were in Europe too—Napoleon, Corsica. But yeah, we're both fathers now. Kind of wow, right?”   2. Fatherhood as Creation's Mirror Alexander: “The power of creation at the human level—another human growing inside a human because two came together. It's not just physical, it's deeply spiritual.” Jason: “It's a symbolization of creation growth—innocence and potential, that's all that's there.” A renewal moment: The newborn reflects creation's essence—pure, unfiltered, and brimming with possibility.   3. Innocence and Potential in Newborns Jason: “What I love from a spiritual perspective is seeing innocence and potential—so beautiful, we forget it.” Alexander: “They're helpless, needing 100% of your attention—like tending the most delicate crops.” Jason: “They're not desensitized like us—they see the world fresh, and we can't limit that.”   4. The Responsibility of Self-Awareness Alexander: “You need self-control and self-awareness to not impress your stifled energy onto the child.” Jason: “Everything you bring to their care opens their potential—or stifles it. There's two options.” Alexander: “You'd want the maximum and the best—hoping they take your best and step above you. That's evolution's point.”   5. Biological Evolution in Parents Jason: “Parents undergo shocking transformations—gray matter increases, prefrontal cortex and hypothalamus grow for bonding.” Alexander: “Oxytocin's through the roof—your senses max out, supercharging your brain.” Jason: “Evolution doesn't stop; having a kid accelerates it for both parent and child.”   6. Sanctification Through Chaos Jason: “Sleepless nights and constant care—it's sanctifying, a space for divine presence.” Alexander: “Try this: Use the newborn as a candle—gaze into their eyes silently. You'll be shocked how long they hold your attention.” Jason: “It's pure connection—a meditation.”   7. The Energy of Naming (Gabrael's Story) Alexander explains naming his son Gabrael Rowin: “Energy in names matters—spelling and meaning align with creation's patterns.” Why “Gabrael” (AEL spelling): “An older, primordial form meaning ‘might of creation,' synced with birth timing and Chaldean numerology.” Rowan: “‘One who lives in righteousness'—congruent energy for his potential.” Jason: “I love that—it's not just a name, it's intentional energy.”   8. Awe and Exhaustion as Spiritual Gifts Jason: “Why do we feel awe in exhaustion after birth?” Alexander: “It's creation reminding you of true purpose—a visceral truth you've ignored, demanding your attention.” Alexander: “You could feel this awe every moment if you paid attention, but the baby forces it. Look at the raw power and beauty.”   Memorable Quotes “The power of creation at the human level—it's a renewal.” – Alexander “Innocence and potential—that's all that's there in a newborn.” – Jason “Your brain evolves as much as the child's—evolution doesn't stop.” – Jason “Creation wakes you up: Look at the raw power and beauty of this.” – Alexander   Resources Mentioned HDL Podcast Archives: Explore all episodes at higherdensityliving.com Coming Soon: Part 2 of this fatherhood series—stay tuned!   Call to Action Subscribe to Higher Density Living for Part 2 and more consciousness explorations. Share your thoughts: How has creation touched your life? Comment below! Visit higherdensityliving.com to browse past episodes and awaken your potential.   Closing Thoughts   Jason and Alexander close Part 1 with excitement for a deeper dive in Part 2, leaving listeners with a powerful reflection: Fatherhood isn't just raising a child—it's a spiritual and evolutionary catalyst. From Gabrael's energy to the awe of exhaustion, this episode beckons you to look within and embrace creation's edge.   Connect with HDL:    Facebook: https://www.facebook.com/highdensityliving Instagram: https://www.instagram.com/hdlspiritualpodcast/ YouTube: https://www.youtube.com/@HigherDensityLiving TikTok: https://www.tiktok.com/@higherdensityliving   Subscribe: Join Alexander and Jason for more journeys into the unseen.  

Presentación del caso – Motivo de consulta y contexto personalUna mujer de 42 años acude a consulta preocupada por su colesterol alto. Viene derivada tras una analítica en la que han detectado hipercolesterolemia leve, y ella cree que puede deberse a los “picoteos” que tiene por la tarde, que últimamente han ido a más. También quería trabajar su relación con la comida. Decía que por las tardes tenía una ansiedad desbordante, que se comía lo que fuera, sin hambre real. Se culpaba constantemente, se sentía fuera de control y con una enorme frustración porque siempre había sido muy consciente de su alimentación. Me cuenta que no entiende por qué le pasa, porque siempre ha comido bien, lleva una alimentación bastante equilibrada, y aunque no hace mucho deporte, se mantiene activa.Trabaja como administrativa en una empresa de seguros. Tiene dos hijos adolescentes, poco tiempo para ella y la sensación constante de que va a mil. Me explica que a media tarde llega a casa, cansada y con ansiedad, y que ahí es cuando arrasa con lo que pilla.Dice que duerme mal desde hace unos meses, que se despierta de madrugada sin motivo, que se nota más irritable y que últimamente le cuesta más concentrarse en el trabajo. También ha notado que su cuerpo ha cambiado: “Estoy más hinchada, me noto más barriga, aunque coma igual”, comenta.Le pregunto por su menstruación, y me dice algo muy típico: “Siempre la he tenido irregular, así que no sé… a veces me viene cada 40 días, a veces se me salta un mes entero, pero esto me pasa desde siempre”.Por eso, ni se plantea que lo que le está pasando pueda tener que ver con la menopausia.Desarrollo del caso – Qué vimos en consultaRevisamos su analítica.Efectivamente, hay una hipercolesterolemia, pero también aparecen otros datos que me llaman la atención:Déficit de vitamina D,Ferritina un poco baja,Magnesio en el límite inferior,Glucosa en ayunas un poco elevada,Y un perfil lipídico alterado, con un LDL elevado y HDL algo bajo.Con todo esto, y teniendo en cuenta la edad, los síntomas, el insomnio, el cambio en la distribución de la grasa corporal, la irritabilidad, la niebla mental y el déficit de vitamina D, empiezo a pensar en una posible perimenopausia.Se lo planteo, y se sorprende. “¿Tan pronto? Si todavía tengo la regla…”, me dice. Le explico que esta etapa puede comenzar años antes de la menopausia como tal, y que lo que le está pasando encaja perfectamente con ese perfil.Intervención – Cómo lo trabajamosEn consulta decidimos abordar el caso desde varios frentes:Alimentación:Adaptamos su pauta para favorecer el control del colesterol, pero también para mejorar su saciedad y estabilidad energética por la tarde.Añadimos más proteína en desayuno y comida.Trabajamos el equilibrio en las meriendas para prevenir los atracones y redujimos los azúcares simples.Incorporamos alimentos ricos en fitoestrógenos y omega 3.Relación con la comida:Exploramos el papel del picoteo como vía de escape ante el cansancio y la frustración.Introducimos estrategias de autocuidado emocional que no pasaran por la comida.Le ayudé a dejar de culpabilizarse y a comprender que no era falta de voluntad: era su cuerpo atravesando una transición.Ejercicio físico:Le recomendé ejercicios de fuerza dos veces por semana, empezando por rutinas sencillas en casa.Incluimos también caminatas diarias para mejorar su metabolismo, descanso y ánimo.Sueño y descanso:Ajustes de hábitos antes de dormir.Rutinas de relajación y revisión del entorno del sueño.Consideramos junto con su médico la suplementación con melatonina.Suplementación:Vitamina D, por el déficit evidente.Magnesio por sus beneficios en esta etapa (descanso, estado de ánimo, regulación hormonal).Omega 3 por perfil lipídico y efecto antiinflamatorio.Evolución y resultadosA las 4 semanas, ya notaba cambios:El picoteo por la tarde se redujo drásticamente.Dormía mejor.Tenía más energía durante el día.Se sentía menos culpable y más conectada con su cuerpo.Y lo más importante: empezó a reconciliarse con esta etapa, entendiendo que no era una enfermedad ni una derrota, sino un proceso natural que, con el enfoque adecuado, podía atravesar con bienestar.A los 3 meses, la analítica mejoró notablemente:Bajó el colesterol total y el LDL.Subió el HDL.Vitamina D dentro de rango.Y, además, había recuperado el control sobre su alimentación sin necesidad de restringir ni contar calorías.ConclusiónMuchas mujeres llegan a consulta preocupadas por su colesterol, su peso o su ansiedad por la comida, sin saber que lo que de verdad está ocurriendo es que han entrado en la perimenopausia.Y como no se lo han explicado, lo viven con culpa, confusión y soledad.Este caso nos recuerda la importancia de mirar más allá del síntoma y de acompañar esta etapa desde la comprensión, el respeto al cuerpo y un enfoque integral.Porque cuando entendemos lo que nos pasa, es mucho más fácil cuidarnos.Conviértete en un seguidor de este podcast: https://www.spreaker.com/podcast/comiendo-con-maria-nutricion--2497272/support.

Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I'm a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients. In this podcast, Dr. Warrick Bishop, a cardiologist and CEO of the Healthy Heart Network, discusses the complexities of HDL cholesterol, often referred to as "good" cholesterol. He explains the roles of different types of cholesterol, specifically Apo B proteins associated with LDL cholesterol, which contribute to plaque formation and cardiovascular risk. While HDL is involved in transporting cholesterol back to the liver, its protective role is more complicated than previously thought.

How Can I Lower My Triglycerides? “Going to the doctor for your fasting lipid panel results can be an exercise in confusion. You will get numbers for your total cholesterol, LDL cholesterol (“unhealthy” cholesterol), HDL cholesterol (“healthy” cholesterol), and triglycerides. Although the major emphasis in treating abnormal lipid panel results focuses on getting LDL cholesterol below a certain level, your doctor might also make recommendations about your HDL and triglycerides.” Listen to today's episode for details, written by Thomas Campbell, MD at NutritionStudies.org  #vegan #plantbased #plantbasedbriefing #lipid #triglycerides #cholesterol #cvd #cardiovasculardisease #lipidpanel   ======================== Original post: https://nutritionstudies.org/lower-triglycerides/  ========================== Related Episodes: 861: Eat Quinoa and Lower Triglycerides? https://plantbasedbriefing.libsyn.com/861-eat-quinoa-and-lower-triglycerides-by-dr-michael-greger-at-nutritionfactsorg  Related Episodes: use search feature at https://www.plantbasedbriefing.com/episodes-search     Search for cholesterol, heart disease ========================= The T. Colin Campbell Center for Nutrition Studies was established to extend the impact of Dr. Campbell's life changing research findings. For decades, T. Colin Campbell, PhD, has been at the forefront of nutrition education and research. He is the coauthor of the bestselling book, The China Study, and his legacy, the China Project, is one of the most comprehensive studies of health and nutrition ever conducted. Their mission is to promote optimal nutrition through science-based education, advocacy, and research. By empowering individuals and health professionals, we aim to improve personal, public, and environmental health. ====================== FOLLOW THE SHOW ON: YouTube: https://www.youtube.com/@plantbasedbriefing     Spotify: https://open.spotify.com/show/2GONW0q2EDJMzqhuwuxdCF?si=2a20c247461d4ad7 Apple Podcasts: https://podcasts.apple.com/us/podcast/plant-based-briefing/id1562925866 Your podcast app of choice: https://pod.link/1562925866 Facebook: https://www.facebook.com/PlantBasedBriefing   LinkedIn: https://www.linkedin.com/company/plant-based-briefing/   Instagram: https://www.instagram.com/plantbasedbriefing/     

Why You Should Listen:  In this episode, you will learn about Metabolic Vulnerability Index (MVX) as an indicator of mortality and longevity. About My Guest: My guest for this episode is Dr. Darren Schmidt.  Darren Schmidt, DC is the Founder of The Nutritional Healing Center of Ann Arbor which is the largest non-insurance nutrition clinic in the country.  His purpose is to bankrupt pharmaceutical companies by teaching doctors how to improve health rather than treat symptoms.  He uses new and old clinical discoveries to solve complex chronic illness with only diet and supplements.  He uses MVX Plus, the best lab test to measure longevity and health, and it also directs the treatment plan. Key Takeaways: What is MVX? What are the 6 factors and 3 indices that are explored with MVX? How might MVX be a better metric for mortality than many conventionally-used metrics today? Can MVX be extrapolated to be used as a measure of health and longevity? What is GlycA?  What drives it? What tools can be used to lower GlycA? What is the connection between GlycA and hypercoagulation? Why is eGFR and kidney health often used on the context of predicting mortality? What is small HDL particle number?  How can it be optimized? What is the Inflammation Vulnerability Index? What is citrate?  What tools can be used to lower it when elevated? What is the connection between citrate and mitochondrial function? What is lactic acidosis? What is learned from looking at valine, leucine, and isoleucine? What steps may be taken if they are high?  If they are low? What is the Metabolic Malnutrition Index? When might a keto diet be appropriate? What does the Metabolic Vulnerability Index tell us? Is MVX impacted by genetics or epigenetics? What is the 7 Step Blueprint to Optimal Health? How do the 7 steps overlap with the 6 MVX factors? Connect With My Guest:  TheNutritionalHealingCenter.com Related Resources: To see the resources in the Show Notes, visit https://BetterHealthGuy.com/Episode216. Interview Date: April 21, 2025 Transcript: To review a transcript of this show, visit https://BetterHealthGuy.com/Episode216. Additional Information: To learn more, visit https://BetterHealthGuy.com. Follow Me on Social Media: Facebook - https://facebook.com/betterhealthguy Instagram - https://instagram.com/betterhealthguy X - https://twitter.com/betterhealthguy TikTok - https://tiktok.com/@betterhealthguy Disclaimer:  The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today's discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority. 

Host: Jason Rigby   Guest: Pam Montgomery   Guest Website: wakeuptonature.com   Podcast Mission: Higher and Saint Living (HDL) aims to explore profound topics that elevate consciousness and foster a deeper connection to the world around us. In this episode, we dive into humanity's relationship with nature and the transformative power of plants with Pam Montgomery.   About Our Guest: Pam Montgomery   Pam Montgomery is an author, teacher, international speaker, and self-described Earth Elder who has dedicated over three decades to exploring the intelligent and spiritual nature of plants and trees. She is the author of two acclaimed books: Plant Spirit Healing: A Guide to Working with Plant Consciousness and Partner Earth: A Spiritual Ecology. Her latest work, Co-Creating with Nature: Healing the Wound of Separation, serves as the foundation for this episode's discussion. Pam operates the Partner Earth Education Center at Sweetwater Sanctuary in Danby, Vermont, a space dedicated to co-creative research and sustainable living with nature. She teaches globally on plant spirit healing, spiritual ecology, and the concept of humans as "Nature Evolutionaries." Pam is a founding member of United Plant Savers and the Organization of Nature Evolutionaries (O.N.E.), and her current passion lies in facilitating plant initiations to guide humanity back to its symbiotic roots.   About Sweetwater Sanctuary   Located in Danby, Vermont, Sweetwater Sanctuary is a sacred space where Pam and her team honor the land, water, and all beings through prayer, ceremony, and offerings. It's a haven for optimal learning and deep healing, encouraging visitors to awaken to natural rhythms and engage in loving kindness. The sanctuary fosters a profound connection with nature, enhancing the sense of sanctuary for all who visit.   Episode Overview   In this episode of the HDL Podcast, host Jason Rigby sits down with Pam Montgomery to explore her book Co-Creating with Nature: Healing the Wound of Separation. Recorded on March 29, 2025, this conversation dives into the consciousness of plants, their role as our elders and partners, and how reconnecting with nature can heal both ourselves and the planet. Pam blends scientific insights, personal anecdotes, and spiritual wisdom to offer a practical yet profound roadmap for living in harmony with "sweet Lady Gaia."   Key Discussion Points 1. Plants as Conscious Partners (03:12 - 06:46) Pam argues that plants are not just alive but conscious beings capable of communicating with us through vibratory resonance (light and sound). She emphasizes their essential role in sustaining life—providing oxygen, food, and medicine—and warns that our disconnect from them is dangerous. Jason references scientific studies showing plants responding to music and words, sparking a discussion on how everything vibrates, including humans and plants.   2. How to Communicate with Plants (06:46 - 13:14) Pam explains that plants fine-tune their resonance to us more effectively than we do to them because they are simply themselves, undistributed by human distractions. Practical tip: Be present with a plant, let it choose you (via attraction, movement, or intuition), and notice the sensations it evokes in your body (e.g., tingling, softness). She introduces biophotons—particles of light at the nucleus of our cells—that create a "laser" of coherence for two-way communication with plants, even across time and space.   3. Plant Initiations and Healing (13:14 - 18:06) Pam contrasts chasing external spiritual practices (e.g., gurus, crystals) with the power of "backyard weeds" like mugwort, which can heal us deeply through symbiotic connection. She shares a story of poke root appearing in her Vermont garden in 2020, a potent immune-supporting plant, as an example of nature responding to human needs. Plants show up where they're needed, offering gifts we often overlook due to our lack of attention.   4. The Wound of Separation (19:11 - 22:22) Pam traces humanity's separation from nature back 12,000 years to agriculture and empire-building, which led to an "amnesia" of our interdependence with the land. This original wound has cascading effects: separation from self, others, and the planet, resulting in widespread illness and disconnection. Biophilia—our innate love of nature—underscores how we're designed to live closely with plants.   5. Uncomfortable Truths and Nature Evolutionaries (22:58 - 26:17) The biggest lie we tell ourselves: Humans are the "crown of creation" and more intelligent than nature. Pam challenges this, citing Darwin's coerced narrative and nature's model of cooperation over competition. On her website, wakeuptonature.com, Pam calls us to become "Nature Evolutionaries," partnering with nature rather than relying solely on technology to "save" the planet.   6. Nature's Communication Networks (26:17 - 33:11) Pam shares a powerful story of a Puyo—an underground waterway portal in Vermont—where she and her husband, guided by Ecuadorian curandera Rocio Alarcon, heard forest spirits sing after a ritual with ayahuasca. She compares nature's mycelium network to the internet, highlighting its efficiency and biomimicry potential.   7. Signs of a Consciousness Shift (33:11 - 37:53) Pam sees plants leading humanity's spiritual evolution, citing the 1960s explosion of consciousness-expanding plants (cannabis, peyote, mushrooms) and modern practices like flower essences and plant initiations. Skeptics miss this hidden sign: Plants have always preceded their animal counterparts in evolution, and they're now guiding us toward unity consciousness.   8. Diving Deeper into Nature (37:53 - 43:23) Unlike spiritual paths that reject the material world, Pam's approach embraces nature as divine, present in everything—not a distant deity. She describes daily "wow moments" (e.g., sunrise walks in Belize) that release oxytocin, the bonding hormone, fostering restoration and connection over stress (cortisol). 9. Healing Through Plants (46:52 - 50:19) Pam cites biophysicist Fritz Popp's discovery that plant biophotons can repattern unhealthy cells' light toward health, offering a cellular-level explanation for plant healing. Beyond science, plants uplift us emotionally and spiritually—e.g., the awe of a redwood forest or the scent of roses—because healing is one of their primary gifts.   10. Mugwort as a Teacher and Soulmate (50:49 - 54:57) Mugwort (Artemisia spp.), known as "Oona, the first herb," moves stagnant energy, aids dream recall (nighttime and shamanic), and reconnects us to our wild, undomesticated selves. Associated with Artemis and the moon, it supports women through life transitions and is a key ally in spiritual healing.   11. Closing Thoughts and Upcoming Projects (56:11 - 58:06) Jason praises Co-Creating with Nature as a timely wake-up call with a heartbeat, inviting listeners to heal themselves and the planet through reverence for nature. Pam previews her work: Plant Initiations: Ceremonies where plants act as elders, guiding us to be "truly human." Offered at Sweetwater Sanctuary and worldwide. Year-Long Course (September 2025): With Emma Fitchett, training facilitators for plant initiations. Online Course: "Co-Creative Partnership with Nature" (8 months). Visit wakeuptonature.com for details.   How to Get the Book Title: Co-Creating with Nature: Healing the Wound of Separation Cost: $27.00 (includes shipping) Order by Mail: Send a check to Pam Montgomery, 1525 Danby Mtn. Rd., Danby, VT 05739 Order Online: Click here Buy it from Amazon     Quotes from the Episode "Plants completely, on all levels—physical, emotional, mental, and spiritual—provide us our life." – Pam Montgomery "The plant can fine-tune its resonance to us... They draw you to them." – Pam Montgomery "We are not the crown of creation. It's about cooperation, not competition." – Pam Montgomery "Plants have always preceded their animal counterparts in evolution... They're guiding us into a quantum leap in consciousness." – Pam Montgomery "Nature is sentient, just like we are. We're equal in this co-creative partnership." – Pam Montgomery     Connect with Pam Montgomery   Website: wakeuptonature.com Facebook: https://www.facebook.com/natureevolutionaries IG: https://www.instagram.com/natureevolutionaries/ Upcoming Event: Stay tuned for a follow-up episode on plant initiations before the September 2025 course launch!     Listener Call-to-Action   Subscribe to the HDL Podcast for more conversations on consciousness and living sustainably. Purchase Co-Creating with Nature to dive deeper into Pam's teachings. Share this episode with someone who loves plants or needs a nature-inspired wake-up call. Leave a review and let us know your favorite takeaway!   Thank you for joining us on this journey to reconnect with nature's wisdom. As Pam says, "We're on the threshold of a tipping point"—let's step into unity together. See you next time on HDL!  

This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright dive into the world of blood fats—unpacking what cholesterol numbers really mean for your health. They break down HDL (the “good” cholesterol), LDL (the “bad” cholesterol), triglycerides, and spotlight the often-overlooked lipoprotein(a), a genetic risk marker with significant consequences for heart health. The team dispels myths about fats in our diet, covers the impact of lifestyle and genetics, and explores how advanced testing can reveal hidden risks. You'll come away understanding which fats matter most, why particle size counts, and what actions can help manage your numbers and protect your heart.Key Takeaways:Blood fats, specifically HDL, LDL, and triglycerides, are critical indicators of cardiovascular risk. Advanced testing can identify dangerous subtypes and genetic markers like lipoprotein(a) that standard panels miss.HDL has benefits, but high numbers don't cancel out high LDL; LDL particle size and count are crucial—small, dense particles are more harmful.Lipoprotein(a) is a major genetic risk factor for heart disease and stroke that isn't modifiable by diet or exercise; new treatments are in development.Plant-based monounsaturated fats (like olive oil and avocados), resistant starches, and soluble fiber offer metabolic and heart-health benefits, but even perfect diets may not lower genetic cholesterol risks.Lifestyle factors—exercise, avoiding smoking, quality sleep, and managing conditions like diabetes—are critical for reducing cardiovascular risk, especially if you have inherited risk markers.Heart health isn't just about body size—“looking healthy” doesn't guarantee healthy arteries; everyone should know their numbers and consider advanced heart scans as needed.Resources:Connect with Dr. Emily Cooper on LinkedIn.Connect with Mark Wright on LinkedIn.Connect with Andrea Taylor on Instagram.Fat Science is a podcast on a mission to explain where our fat really comes from and why it won't go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn't a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.If you have a question for Dr. Cooper, send an email to dr.c@fatsciencepodcast.com. If you have a show idea, feedback, or just want to connect, you can also reach us us at info@diabesityinstitute.org.Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

Send us a textShort Summary: Heart health and the ketogenic diet, with expert insights from a cardiologist and researcher.About the guest: Matthew Budoff, MD, is a preventive cardiologist and professor of medicine at UCLA School of Medicine.Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and everyone on YouTube. Partial versions are available elsewhere. Transcript and other information on Substack.Episode Summary: Dr. Matthew Budoff discusses cholesterol, heart disease, and his study on the ketogenic diet's impact on lean, metabolically healthy individuals with high LDL cholesterol. He explains LDL, HDL, and triglycerides, debunking myths about their direct link to heart disease, and emphasizes the importance of coronary calcium scans to assess plaque buildup. Budoff also covers statins, dietary cholesterol, and personalized heart health strategies.Key Takeaways:LDL cholesterol is not a definitive predictor of heart disease; plaque buildup, assessed via coronary calcium scans, is a better indicator.Lean metabolically healthy people on a ketogenic diet may have high LDL without increased plaque progression after one year.Coronary calcium scans, costing ~$100, are recommended for men around age 40 and women around 45-50 to evaluate heart disease risk.Statins effectively lower LDL and can reverse soft plaque, but may be overprescribed for those without plaque buildup.Dietary cholesterol has minimal impact on blood cholesterol, as the liver produces ~85% of it.Ketogenic diet can aid weight loss & diabetes control but may cause high LDL in some lean individuals, known as lean mass hyper-responders.Plaque progression depends more on existing plaque than LDL levels in metabolically healthy ketogenic diet followers.Heart health varies widely due to genetics and other unknown factors, underscoring the need for personalized assessments.Related episode:M&M #158: Ketosis & Ketogenic Diet: Brain & Mental Health, Metabolism, Diet & Exercise, Cancer, Diabetes | Dominic D'AgoSupport the showAll episodes, show notes, transcripts, etc. at the M&M Substack Affiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Readwise: Organize and share what you read. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription. MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off. For all the ways you can support my efforts

Send us a textLas grasas alimenticias han sido injustamente demonizadas durante décadas, pero la verdad es mucho más matizada y fascinante. La grasa no solo es densa en calorías (9 calorías por gramo), sino que es literalmente alimento para el cerebro, ya que aproximadamente el 60 % del cerebro está compuesto de tejido graso. Este macronutriente, mal entendido, es esencial para la producción de hormonas, la correcta absorción de las vitaminas A, D, E y K, la estructura celular y el almacenamiento de energía.Comprender las tres categorías principales de grasas puede transformar tu relación con la comida y la salud. Las grasas insaturadas (presentes en aguacates, aceite de oliva, frutos secos, semillas y pescados grasos) favorecen la salud cardíaca al aumentar los niveles de colesterol HDL (bueno). Las grasas saturadas procedentes de productos animales, coco y palma deben limitarse, especialmente para quienes tienen problemas de colesterol. La categoría más problemática, las grasas trans, se encuentran en los alimentos procesados ​​y contribuyen a un mal pronóstico cardiovascular al aumentar el colesterol malo y disminuir el bueno. Ve más allá de la afirmación de "0 gramos" en las etiquetas nutricionales y revisa los ingredientes en busca de "aceites parcialmente hidrogenados", el verdadero indicador de estas grasas dañinas. ¿La buena noticia? Incorporar grasas saludables a tu rutina diaria es sencillo y delicioso. Prueba a añadir rodajas de aguacate a tus comidas, a sustituir la mantequilla por aceite de aguacate al cocinar a altas temperaturas, a espolvorear frutos secos o semillas en el yogur o a usar aceites en aerosol para controlar las porciones y disfrutar de platos sabrosos. Recuerda que las grasas saludables te ayudan a sentirte saciado, a estabilizar el azúcar en sangre y a favorecer numerosas funciones corporales. No les temas a las grasas: conócelas, elige con cuidado y tu cuerpo (especialmente tu corazón y tu cerebro) te lo agradecerá. ¿Quieres más orientación? Consulta nuestros recursos educativos y síguenos en Instagram @nutrition_with_leonila para recibir apoyo continuo en tu camino hacia la nutrición.Guia de Grasas Saludables Thank you for listening. Please subscribe to this podcast and share with a friend. If you would like to know more about my services, please message at fueledbyleo@gmail.comMy YouTube Channel https://www.youtube.com/channel/UC0SqBP44jMNYSzlcJjOKJdg

Colesterol: el villano mal entendido¿Tienes el colesterol alto? ¿Te han dicho que debes preocuparte? Hoy desmontamos mitos y te explicamos por qué el colesterol no es el enemigo que siempre nos han pintado. En este episodio hablamos de: ✅ Qué es realmente el colesterol y para qué lo necesita tu cuerpo.✅ Qué significan el LDL, HDL, los triglicéridos y las apolipoproteínas ApoA y ApoB.✅ Por qué el colesterol en sí no es peligroso, sino que hay que mirar el riesgo cardiovascular global.✅ Qué alimentos pueden ayudarte a regular tus niveles de colesterol.✅ Cuándo es necesario medicarse y qué otros marcadores conviene tener en cuenta.✅ Y, como siempre, desmontamos mitos: ¿el huevo sube el colesterol?, ¿el colesterol total lo dice todo?, ¿todo el mundo con colesterol alto necesita estatinas?Un episodio claro, directo y con mucha información útil para que entiendas tu analítica, tomes decisiones con criterio y no te asustes con una sola cifra.Conviértete en un seguidor de este podcast: https://www.spreaker.com/podcast/comiendo-con-maria-nutricion--2497272/support.

Deutschland liegt bei der Lebenserwartung im westeuropäischen Vergleich auf dem letzten Platz. Insbesondere kardiovaskulär bedingte Erkrankungen sind Todesursache Nr. 1. Was machen andere Länder besser? Sie setzen in der Prävention früher an und behandeln nicht erst, wenn es zu spät ist, sagt die Lipidologin Dr. Katrin Gebauer. Im Podcast erklärt sie, wo sie hier noch Nachholbedarf sieht und welche Faktoren sich gezielt beeinflussen lassen.

Are you aware of your lipid profile? You need to be..and Dietitian Dad (Mike) explains why in this informative episode. He looks at the latest studies on how to raise HDL (good cholesterol) levels as well as other recent studies around fat/cholesterol. Plus: a new restaurant just opened in his area and this set off a nerve..get ready for a rant! Enjoy and don't forget to leave a review!!

In today's episode of Barbell Shrugged you will learn: What are lipids What is cholesterol The difference between HDL and LDL cholesterol Why there is no such thing as “good” or “bad” cholesterol What are the bloodwork numbers for optimal cholesterol What is the perfect ratio of HDL and LDL Ratios for Triglycerides to HDL for optimal health Mechanisms for regulating cholesterol in the liver Why saturated fats are not bad and how your body uses them Cholesterols role in testosterone production To learn more, please go to https://rapidhealthoptimization.com Connect with our guests: Anders Varner on Instagram Doug Larson on Instagram Coach Travis Mash on Instagram Dan Garner on Instagram

One of the most Popular and Misunderstood topics is Cholesterol and Statins with Clinical Biochemist Phil George Series #2 Are you taking a statin and experiencing unexpected aches and pains? Or perhaps your doctor has recommended starting on a statin, and you're seeking a second opinion? Tune in as biochemist Phil George unravels the misconceptions surrounding cholesterol, LDL, and HDL. In this enlightening episode, you'll gain a fresh perspective on lipids and learn how they truly impact your health. Don't miss this opportunity to see cholesterol in a whole new light! Bio: Phil has spent most of his adult life educating and helping clients live a healthier, more fulfilling life. He is a clinical biochemist/certified personal trainer/health coach. As a biochemist, he was trained to understand “the mechanism of action” or what is causing the problem as opposed to just throwing medications at the illness. Many clients/listeners say that Phil makes complicated subjects much easier to understand. He was hired by a veteran's group and gave seminars throughout New England. Phil continues to give seminars to senior centers and other groups in New England. For the past two years Phil has been the host of a popular radio and TV show in Central Massachusetts, WellnessWave Radio,LLC. on WCRN in Boston, MA. Affiliations: Society of Metabolic Health Practitioners Nutrition Coalition Root Cause Practitioners Please feel free to email him at philgeorge@charter.net with any health/nutrition/exercise questions. https://www.wellnesswave.net/ Be sure to tune into his Radio Show “Wellness Wave Radio LLC” on Dreamvisions 7 Radio Network every Wednesday 11am/11pmET Learn more: https://dreamvisions7radio.com/wellness-wave-radio-llc/  Call In and Chat with Deborah during Live Show: 833-220-1200 or 319-527-2638 Learn more about Deborah here:  www.lovebyintuition.com

See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog Last time we reviewed why interpreting your lab may lead you to the wrong diagnosis and treatment.  Today we continue our review of each lab panel and why the reference ranges on your lab results may not be the “Healthy Normal Range” that you should compare your results to. Lab reference ranges are established with a one-size-fits-all mentality, ignoring the numerous variables that influence blood results. Have you ever tried on a “one-size-fits-all “ANYTHING? Those clothes may fit 20% of the population but for the rest of us, the garment doesn't fit our width, weight or height! All one-size-fits-all lab reference ranges are much the same.  For example, the standardized “reference ranges” in the US serve as a one-size-fits-all “ideal range” applied to everyone, despite genetic differences, varying latitudes, and the diverse diets that characterize the American multiethnic population. This presents the first problem with using a single range for all people: variations among individuals based on differing genetic needs.  The second issue is that the ranges on the lab report indicate the minimum levels necessary for survival, not necessarily the healthiest blood levels for most individuals. Another example of one size doesn't fit all is the reference range for women's hormones. A range is displayed for cycling women, but there is no healthy range for menopausal women.  Does the range displayed refer to menopausal women with HRT, or menopausal women without HRT to treat their menopausal symptoms? Is the range based on what is healthy, or what is average? We aren't sure. Labs don't ask patients questions that could help interpret lab values. Therefore, they cannot provide a truly diagnostic reference range for any illness. They only consider gender and age, as reference ranges are solely adjusted for these two factors.  A doctor must interpret individual lab results alongside a patient's medical and surgical history, including established diseases, medications, supplements, hormonal treatments, and past lab values. For instance, laboratory companies should offer reference ranges based on whether a patient is menopausal, a woman is undergoing ERT, a man is receiving testosterone, a patient is on thyroid medication, a person is being treated for diabetes, or the diabetic tests are performed to diagnose diabetes.   Some Reference Ranges are Based on comparing results to Misleading formulas The best example of this issue is the Lipid Panel. Doctors use this panel to determine a person's risk for heart attacks caused by atherosclerosis. Most doctors don't know the formula for determining Total Cholesterol. This test doesn't predict heart disease in most patients, as the formula used to arrive at that number is not indicative of the disease. However, doctors have been advised that when   total cholesterol levels are high, a patient should start taking a statin, a drug that reduces blood cholesterol and sometimes lowers the rate of heart attacks in certain individuals, though it is rarely predictive in 50% of the population. The problem with the lipid panel is twofold: the LDL level indicates future atherosclerosis in only about 50% of the population and is not a specific test for future heart disease risk. Total cholesterol is even less predictive of heart disease because it stems from a flawed formula. Doctors interpret a high Total Cholesterol level as an indication that a patient may be at increased risk for heart disease in the future. When I test patients with elevated Total Cholesterol or high levels of LDL using a Cardiac Calcium Scan to measure plaque, only half of them actually produce plaque, and consequently, are not at risk for atherosclerotic heart disease. I believe that the Total Cholesterol number is derived from an inaccurate formula for determining a person's risk of future heart disease. The Total Cholesterol number is calculated using a flawed equation. The equation is as follows:         LDL + 1/5 Triglycerides+ HDL = Total Cholesterol Total Cholesterol = LDL (bad cholesterol) + 1/5 Triglycerides (high risk factor) + HDL (good cholesterol) Let's examine this formula simply like this:   Bad + Bad + Good does not equal Bad. Due to this incorrect formula, thousands, if not millions, of patients have been prescribed statin drugs for a lifetime without justification!  Statins carry risks. The list of side effects is extensive and includes muscle deterioration and statin-associated dementia. Unfortunately, most people who experience statin side effects are women. Women tend to have higher HDL levels than men. Additionally, they typically do not have atherosclerotic plaque until menopause and usually do not develop it after menopause if they undergo estrogen replacement therapy! This gender issue is just one of the problems with laboratory reference ranges that are not adjusted for sex. The total cholesterol values were developed solely from the blood levels of men, who typically have lower HDL levels. Women were excluded from the tests conducted to create this blood panel. For women, I dispel the myth that high total cholesterol predicts heart disease by recommending a Cardiac Calcium Scan to check for plaque. If a woman has no plaque by the age of 50 and is taking estrogen, she is unlikely to develop plaque in the future.  I still test them every 2-3 years to ensure that no metabolic changes have altered their risk, but I don't put much faith in the unreliable cholesterol blood panel. There is another blood test that has deceptive reference ranges: IGF-1 How about the GH-IGF-1 test, the test for Growth Hormone?  IGF-1 is a metabolite of GH that we can measure to determine how much the patient produces.  This hormone aids in healing and replenishing aging cells in patients after their growth is complete.  The healthy normal range with which I was trained, (150-350 MIU), has been changed to an age-adjusted normal that compares a person to others in her age category who had their blood drawn the previous year.  What is wrong with this? Growth hormone (GH) decreases with age and contributes to the declining health people experience as they grow older. Similarly, IGF-1 diminishes with age and illness, which means that the “reference range” essentially reflects that you are “average for the sick individuals who visit Quest to have their IGF-1 levels checked. ” IGF-1 levels can be enhanced through weight loss, testosterone replacement, and an increase in muscle mass. The current reference range does not indicate health or illness; it merely shows whether you fall within the average for your age group. This non-scientific method of determining “health” is widespread in contemporary medicine. By comparing aging individuals to others within the same age group, for hormones that decline with age, based on samples from sick patients who visit a specific lab in the past year, these labs label patients as “healthy” even when they are as ill as other individuals their age who go to that lab! This practice constitutes age discrimination! Regarding hormones, the levels we maintained during our fertile and youthful years correspond to the blood levels indicative of health in all individuals ages. For example: People who check their IGF-1 (Growth Hormone) levels and see a low “52 ng/ml” might feel satisfied that they are within the standard range (50-280 ng/ml). However, they may not realize that this range applies to older, unhealthy individuals, not to healthy young ones (150-350 ng/ml).  This is just one example of the issues that arise when non-medical individuals, who do not monitor these tests regularly, draw conclusions from the numbers.   Some illnesses require more than one blood test for diagnosis If you consider only one of the three tests for diabetes or prediabetes (Fasting Blood Sugar, HbA1c, and Insulin), you cannot self-diagnose as diabetic, prediabetic, insulin resistance or healthy.  Diabetes is a disease that has coincided with the rising number of obese individuals.  Both conditions affect nearly 50% of the American population. Blood tests cannot be interpreted accurately unless a patient has fasted for 12 hours; all three tests should be evaluated. When diagnosing diabetes and insulin resistance, we perform three tests to assess whether a patient has insulin resistance, prediabetes, or diabetes. These tests guide our diagnosis and inform the treatment we provide based on their results. Fasting insulin is a highly misleading test. Over 15 years ago, a significant study was conducted that was believed to change the reference ranges for fasting insulin.  The new range set for normal fasting insulin was less than 10 mIU/ml. By publishing the reference range less than 18 mIU/ml, they miss diagnosing many patients with insulin resistance HBA1C is a test that gives a value of average blood sugar over three months. The results are often used alone to determine prediabetes and diabetes; however, considering all three aspects makes the diagnosis and treatment plan more specific for the patient. FBS (fasting blood sugar) is the third diabetes test. It is generally used as a screening test that prompts the ordering of the other two blood tests; however, some patients exhibit symptoms of diabetes and insulin resistance without having elevated fasting insulin levels. Many medications can raise diabetic test values, causing a patient to seem diabetic when they are actually experiencing a side effect of the drug.  One such medication is Atorvastatin.  The solution is not treating diabetes but rather adjusting the medication.  Hormone tests are especially challenging to interpret, Especially when testing free Testosterone in women Here are the problems with the free Testosterone test itself: Women have extremely low levels of free testosterone and testosterone compared to men. I have been informed by Quest that women's free testosterone levels are not reliable with current methods because they are not always reproducible when a test is conducted twice on the same day. This leads me to believe that hormone levels do not always reflect the actual blood levels of free testosterone and estradiol. The levels of testosterone in women are based on menopausal levels of T. Women have long been thought to not produce testosterone, so the “normal” levels are quite low, and 0 used to be considered normal- until one day I managed to persuade a medical director at Quest to increase it to 0.2! Women's testosterone is influenced by their production of E2 and E1, which inactivate free T. Women vary in how their cells respond to testosterone and estradiol. Receptor sites and their genetic acceptance of hormones can mean that the same blood level of testosterone in both sexes does not produce the same effects in all patients. Some women (and men) are resistant to E2 and T, or to one of the two. This indicates that the hormone-free T level may be optimal for one woman while being ineffective in alleviating any low T symptoms for another. The latter individual is T resistant, and we currently have no means outside of research labs to determine which women are sensitive and which are resistant. This requires that doctors and NPs look beyond typical reference ranges to effectively manage E2 and T replacement for women. Lastly some labs use the total testosterone level through a formula determine the free T. This carries inherent risks of reporting the wrong active level of testosterone. Total and free testosterone blood levels for men, are derived from results of older men, rather than from the blood levels that indicate health and the levels at which men experience no symptoms. This leads men to believe they are normal, even though they are symptomatic, and they can't get treatment. There is no time to discuss the reference ranges for LH, FSH, Estradiol, and Estrone; these topics will be addressed in a future blog. I hope I have encouraged you to review your blood work with your doctor or Nurse Practitioner, and not to act as your own doctor by interpreting your blood tests.

Is LDL cholesterol the best way to measure and predict heart disease?New research suggests no!Dave Feldman is an engineer turned citizen scientist who has devoted his life to understanding a phenomenon that some individuals around the world are experiencing: a robust increase in LDL cholesterol while on a ketogenic diet.Dave's past research has identified a unique phenotype dubbed Lean Mass Hyper-Responders (LMHRs). LMHRs respond to ketogenic therapy with a metabolic profile that includes elevated LDL-C and ApoB levels with otherwise healthy metabolic markers, including low triglycerides, high HDL, low blood pressure, low insulin resistance, and low BMI.In Dave's most recent publication, what most doctors would consider dangerously high LDL levels in LMHRs did not correlate with an increased risk of heart disease.In this video, Dr. Bret Scher sits down with Dave Feldman to discuss this groundbreaking study and its implications for ketogenic therapy and cardiology.Key Takeaways:LMHRs on a long-term ketogenic diet who show elevated LDL can show robust metabolic healthLDL-C and ApoB were not linked to plaque progression in LMHRsExisting plaque did predict future plaque accumulation in LMHRsIndividualized approaches to cardiovascular risk assessment are crucial to serve this group better.

This interview with JACC: Associate Editor Neha J. Pagidipati, MD, FACC, and author Kausik Ray, MD, FACC, reviews Dr. Ray's phase one study on solbinsiran, an siRNA therapy targeting ANGPTL3 to reduce triglycerides and cardiovascular risk. Dr. Ray explains the study's findings, including significant reductions in triglycerides, ApoB, and LDL, with a favorable safety profile. The conversation also touches on the broader landscape of ANGPTL3 inhibitors, the implications of HDL reduction, and the anticipation of phase two results to be presented at ACC 2025.

Metabolic syndrome (MetSyn) is a cluster of conditions, such as increase in waist circumference, dyslipidemia (elevated triglyceride levels and reduced HDL), increased blood pressure, and increased fasting blood sugar levels that is related to insulin resistance, diabetes, and elevated risk of cardiovascular disease. Women with PCOS have a significantly higher prevalence of metabolic syndrome (MetS) compared to the general population, with studies indicating a prevalence of around 43-47% in PCOS women. PLUS, there is a high prevalence of moderate to severe depressive symptoms and depression in adults and adolescents with PCOS; therefore, screening for depression in all adults and adolescents with PCOS is encouraged. In this episode, we will review a new publication for the J Clinical Endo & Metabolism discussing this combination (PCOS and depression/anxiety) and the MetSyn, and we will review the EXPANDED indications for metformin for metabolic syndrome prevention/treatment according to the 2023 PCOS updated guidance.

You hit 38, and all of the sudden the same stuff isn't working like it used to! So, what's going on? Dr. Mariza tackles the science behind weight changes in midlife, and how to build metabolic resilience and insulin sensitivity as you age. We also talk through lab work and how to make changes based on your blood work and symptoms. Perimenopause doesn't have to suck, and small shifts can completely change your life in the decades to come!Timestamps:[3:12] Interview with Dr. Mariza[3:26] What was the moment you knew you were in perimenopause? [7:03] What is happening to our hormones mid-life?[16:20] Where should women realistically start?[19:33] Are you ok with getting baseline markers in a blood test or is there a better way? [30:48] Is it normal for testosterone to be low and decline as women are in their upper 30s?[34:07] What is metabolic flexibility and how do you know if you actually have it?[37:03] Is there really a thing as being “in balance” with your hormones?[39:02] I'm curious about when the right time is to get on HRT - should I start it as a preventative measure or wait until I experience symptoms?[40:44] What should you test or do when you're doing everything right and still gaining weight? [47:16] How does blood glucose drive a change in fat storage and how can we improve that? [53:14] I am 41 and the same weight as last year but my middle is different - no change in diet or exercise, in fact I'm more disciplined than I've ever been. Help! [57:06] How do we combat burnout on all things “life” when there's no choice but to keep going?[1:04:34] Are you more sensitive to cortisol in mid-life and perimenopause and, if so, how?Episode Links:Visit Dr. Mariza's WebsitePerimenopause Survival GuideLab tests to run:Complete blood countComprehensive metabolic panel (should have fasting glucose included)Vitamin D3 – Needs to be 50+Fasting insulin - 5 or belowFasting blood glucose - 85 ml or lowerHemoglobin A1CC-Reactive Protein (CRP): Under 1Lipid panel: HDL above 50Apo B Test - under 85Uric acidHormonesCortisolFull testosterone panelFull thyroid panel Estradiol Progesterone Sponsors:Go to wellminerals.us/creatine and use code WELLFED to get 10% off your order. Launching April 1st!Go to http://mdlogichealth.com/mc  and use coupon code WELLFED for 10% off.Go to https://thisisneeded.com/  and use coupon code WELLFED for 20% off your first order.Go to boncharge.com/WELLFED and use coupon code WELLFED to save 15% off any order.

Oatmeal has long been considered a heart-healthy breakfast, but is it really as good for us as we think? In this episode, Jonathan and Sarah break down the great oat debate. First, they explore the different types of oats - instant, rolled, and steel-cut and how processing impacts their nutritional value. Then, they put oats to the test using continuous glucose monitors (CGMs), comparing instant to steel-cut, with and without toppings, to demonstrate how blood sugar works. Sarah also discusses wider debates around oats: Are pesticides a concern? Is oat milk as healthy as it claims? Finally, she shares the ultimate guide to choosing the healthiest oats - and for those who prefer alternatives, she's got delicious, nutrient-packed swaps to try.

Join the Behind the Knife Bariatric Surgery Team as they kick off 2025 with a crucial discussion on pediatric and adolescent bariatric surgery. Drs. Matt Martin, Adrian Dan and Katherine Cironi delve into the latest ASMBS guidelines, comparing long-term outcomes of gastric bypass and sleeve gastrectomy in adolescents versus adults. They explore key comorbidities, including type 2 diabetes, hypertension, and orthopedic issues, and emphasize the importance of early intervention. This episode also tackles the complex ethical considerations surrounding surgery in this vulnerable population, including consent, multidisciplinary care, and the evolving role of medical therapies like GLP-1 agonists. Show Hosts: - Matthew Martin - Adrian Dan - Katherine Cironi Learning Objectives:  ·  Identify the current ASMBS guidelines for pediatric and adolescent bariatric surgery, including BMI thresholds and associated comorbidities.  ·  Describe common comorbidities seen in the pediatric population eligible for bariatric surgery, such as type 2 diabetes, hypertension, and orthopedic issues.  ·  Compare and contrast long-term outcomes of bariatric surgery (gastric bypass and sleeve gastrectomy) in adolescents and adults, including remission rates of comorbidities and reoperation rates.  ·  Discuss the importance of a multidisciplinary approach, including psychological and ethical considerations, when evaluating adolescent patients for bariatric surgery.  ·  Explain the ethical framework used in evaluating adolescents for bariatric surgery, including consent/assent, parental involvement, and addressing potential coercion.  ·  Recognize the evolving role of medical management (e.g., GLP-1 agonists) in conjunction with or as an alternative to bariatric surgery in adolescents. Article #1: Inge 2019 – Five-year outcomes of gastric bypass in adolescents as compared with adults https://pubmed.ncbi.nlm.nih.gov/31461610/ - The cumulative effect of sustained severe obesity (BMI >35) from adolescence into adulthood increases the likelihood of diabetes, hypertension, respiratory conditions, kidney dysfunction, walking limitations, and venous edema in legs/feet (when compared to adults that did not report severe obesity in adolescence) - American Society for Metabolic and Bariatric Surgery (ASMBS) guidelines for adolescents who should be considered for bariatric surgery: BMI is ≥35 with a co-morbidity or if they have a BMI ≥40 (class 3 obesity, 140% of the 95th percentile) - This article utilizes the Teen-Longitudinal Assessment of Bariatric Surgery (TEENS LAB) and LABS (adults) databases to evaluate the outcomes of adolescents vs. adults who underwent bariatric surgery Roux-en-Y gastric bypass (2006-2009) - 161 adolescents (13-19 at the time of surgery) with severe obesity (BMI>35) vs 396 adults (25-50 years old at the time of surgery) who have remained obese (BMI>30) since adolescence  - Both groups had the gastric bypass procedure as their primary bariatric operation  - Both groups had unadjusted similar demographics, however, BMI was higher in adolescence (54) when compared to adults (51)  - Results were analyzed using linear mixed and Poisson mixed models to analyze weight and coexisting conditions - After surgery, adolescents were significantly more likely than adults to have remission of type 2 diabetes and hypertension - Increased likelihood of remission of diabetes due to the shorter duration of diabetes, lower baseline glycated Hgb, less use of medications, and increased baseline C-peptide levels  - Increased vascular stiffness in adults along with a longer duration of hypertension make the cessation of hypertension less responsive with surgery in adults  - No significant difference in percent weight changes between adolescents and adults 5 years after surgery  - Both adults and adolescent groups had decreased rates of hypertriglyceridemia and low HDL levels, albeit not significantly different when comparing the two groups  - Of note, the rate of abdominal reoperations was significantly higher among adolescents (20%) than among adults (16%) with cholecystectomy representing nearly half the procedures in both groups - Limitations - At baseline, adults had a high prevalence of both diabetes and hypertension - only 14% of adolescents had diabetes vs 31% of adults  - Only 30% of adolescents had hypertension vs 61% of adults  Article #2: Ryder 2024 – Ten-year outcomes after bariatric surgery in adolescents  https://pubmed.ncbi.nlm.nih.gov/39476348/ - The goal is to discuss the long-term durability of weight loss and remission of coexisting conditions in adolescents after bariatric surgery  - This article utilizes the Teen-Longitudinal Assessment of Bariatric Surgery (TEENS LABS) database to evaluate the 10-year outcomes in adolescents who underwent gastric bypass or sleeve gastrectomy  - 260 adolescents with an average age of 17 years old at the time of surgery (ages ranged from 13-19 years old) - 161 adolescents underwent gastric bypass, 99 adolescents underwent sleeve gastrectomy  - Results were analyzed using propensity score-adjusted linear and generalized mixed models  - At 10 years, the average BMI had decreased significantly with both groups experiencing about a 20% change in BMI on average - To assess comorbidities, both groups were analyzed together -  55% of patients who had DM2 at baseline, were in remission at 10 years - 57% of patients who had HTN at baseline, were in remission at 10 years -  54% of patients who had dyslipidemia at baseline, were in remission at 10 years - Limitations  - Neither of these studies compare surgery to medical management. GLP-1s have shown promise for weight loss management but we need more data in terms of long-term outcomes in co-morbidities like diabetes, hypertension, dyslipidemia  - Highlighted Outcomes  - Metabolic bariatric surgery is quite effective in the adolescent population  - Adolescents tend to have weight loss that is similar to that of adults and improved resolution of comorbid conditions (DM2, HTN, dyslipidemia) Article #3: Moore 2020 – Development and application of an ethical framework for pediatric metabolic and bariatric surgery evaluation https://pubmed.ncbi.nlm.nih.gov/33191162/ - The purpose of this paper is to describe the ethical framework that supports the use of metabolic & bariatric surgery (MBS) on the principle of justice, and how providers can conduct a thorough evaluation of patients presenting for these surgeries - Highlights adolescents with intellectual and developmental disabilities (IDD) and preadolescent children who pose more ethical questions before considering surgery  - This article utilizes the bariatric surgery center at one children's hospital and the institution's ethics consult service to develop an ethical framework to evaluate pediatric patients seeking bariatric surgery – using the national ASMBS guidelines  - This ethical framework utilized 4 central ethical questions 1.     Should any patients be automatically excluded from evaluation for MBS? 2.     How should it be determined that the benefits of MBS outweigh the risks? 3.     How do we ensure the patient fully understands and is capable of cooperating with the surgery and follow-up care? 4.     How do we make sure the decision to have surgery is truly voluntary, and not coerced by family or others? - Results: this ethical framework was discussed in depth in two case studies  - Overview of framework: an ethical question would arise from the bariatric team they would review & apply the ethical framework. The question is either resolved by the bariatric team OR ethics consult, continue pre-operative workup vs no surgery - Case 1: 17M (BMI 42) with a history of autism spectrum disorder, pre-DM, depression with behavior challenges, HTN, dyslipidemia. Testing at school demonstrates intellectual functioning at a fourth-grade level. Pt lives with mom and 11-year-old sister. Mom endorses food insecurity (on supplemental nutrition assistance benefits) and struggles with her son's large intake of food.  1.     Co-morbidities should not be exclusionary, but pt should undergo a comprehensive psychosocial evaluation with attention to family dynamics and support and the patient's decision-making capacity  2.     Discuss benefits vs risks. Benefits – decreased progression of DM2, HTN, hyperlipidemia, cardiometabolic dx. Risks – gastric leak, infection, bleeding, dumping syndrome, etc.  3.     Can assess decision-making capacity with the surgical team or if need be other teams. In this case, the pt had limited decision-making capacity  - His level of understanding remained stable during the pre-op visits, and he gave assent to surgery - The mom identified a second source of support (extended family) - The team talked to both the patient and mother alone and then, together, found that the patient developed an independent desire for surgery, and thus moved forward.  - Case 2: 8F (BMI 50) with a history of mod OSA, L slipped capital femoral epiphysis s/p surgical stabilization (6 mos prior). The patient is neurotypical & excels in school, and lives with mom & dad. Referred by mom & dad (mom with a recent history of sleeve gastrectomy).  1.     An 8-year-old should not be discriminated against based solely on age, but the patient should be offered more conservative/less invasive options before OR.  a.     In this case, the family had not yet been offered these nonsurgical approaches (structured weight management program, physical support, dietician) 2.     Discuss benefits vs risks. Benefits – preventing progression of hip disease, improvement of OSA, decreased risk of cardiometabolic dx. Risks – anatomic/infectious/nutrition risks  3.     Decision-making capacity was assessed. Found that the parents were more advocating for the surgery saying she has a poor quality of life physically and socially. When the patient was separated from her parents, she said she could lose weight if she had healthier foods at home and someone to exercise with. The patient had decision-making capacity & did not assent to surgery.  4.     When the ethics team interviewed the patient and parents, the parents had a strong preference toward surgery vs patient was scared of surgery and wanted to try other approaches first  a.      Decided that the child's dissent outweighed the medical necessity for surgery and that there were conservative treatment options still available to try  - Highlighted Outcomes  - ASMBS guidelines give us good direction on who qualifies for surgery and emphasize an interdisciplinary approach to decision-making. The decision to pursue surgery should always weigh the benefits and risks and should be made collaboratively with the patient, family, and care team ***SPECIALTY TEAM APPLICATION LINK: https://docs.google.com/forms/d/e/1FAIpQLSdX2a_zsiyaz-NwxKuUUa5cUFolWhOw3945ZRFoRcJR1wjZ4w/viewform?usp=sharing Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.

RUNDOWN   Mitch and Hotshot break down Super Bowl 59, admitting their lack of enthusiasm for both the Eagles and Chiefs fan bases but finding unexpected entertainment in the blowout. They discuss Tom Brady's underwhelming debut as a Fox analyst, noting his lack of personality and insight compared to past greats like John Madden. Reflecting on the halftime show, Mitch wonders if he's officially aged out of enjoying Super Bowl performances, realizing how modern entertainment trends no longer resonate with him. Dr. John Osborne joins the show for his annual heart health discussion, emphasizing the importance of a coronary artery calcium (CAC) score—a quick, affordable test that can detect heart disease decades before symptoms appear. He debunks common cholesterol myths, explaining that genetics play a bigger role than diet and that HDL (the "good cholesterol") isn't as protective as once thought. With heart disease remaining the leading cause of death, he urges listeners to take proactive steps through prevention, lifestyle changes, and early screenings. The Mariners No-Table tackles Seattle's frustrating offseason, dissecting Jerry Dipoto's comments suggesting the team didn't have many holes to fill despite an anemic offense. While Dipoto takes criticism, analysts Joe Doyle and Brady Farkas argue that ownership's unwillingness to spend is the real obstacle, leaving glaring gaps in the lineup. They also discuss potential prospect call-ups, bullpen depth, and whether the current roster is strong enough to compete in 2024. Christian Capel from On Montlake breaks down Washington football's eventful offseason, including major coaching staff turnover and roster changes through the transfer portal. He evaluates the Huskies' top-25 recruiting class, the challenges of retaining talent in the NIL era, and expectations under new head coach Jedd Fisch. With a Big Ten schedule ahead, the program looks to rebuild and position itself for long-term success.   GUESTS   • Dr. John Osborne | Cardiologist • Mariners No-Table | Joe Doyle (Over Slot) & Brady Farkas (Sports Illustrated Now M's Editor) • Christian Caple | The Athletic, On Montlake   TABLE OF CONTENTS   1:34 | Super Bowl 59, Eagles Fans, and a Presidential Golf Outing 12:16 | Clip of the Week: Mark Cuban on "unique situations" 20:33 | Super Bowl 59 Reactions: Eagles Blowout, Brady's Commentary, and a Halftime Epiphany 37:26 | GUEST: Dr. John Osborne | Cardiologist - Preventing Heart Disease: The Test Every Adult Over 40 Should Get 45:42 | GUEST: Mariners No-Table | Joe Doyle (Over Slot) & Brady Farkas (Sports Illustrated Now M's Editor) - Mariners Fans Frustrated as Ownership Avoids Spending to Improve Offense 1:00:16 | GUEST: Christian Caple (On Montlake) - Washington Football Navigates Major Changes in Coaching, Roster, and NIL Era 1:50:43 | The Other Stuff Segment: • Super Bowl Halftime Shows controversy • Mariners' Offseason Comments • Randy Moss cancer diagnosis and return • Nate Robinson kidney transplant • Vegas brothel Super Bowl offer • Cooper Kupp trade rumors • Marcus Jordan DUI and cocaine arrest • MLB umpire betting scandal • UMass student tuition contest controversy • Warren Moon's son commits to Washington, • RIPs: Howard Twilley • Headlines: Artificial shark reproduction, Waffle House egg surcharge, Stolen olive oil and egg heists, Man warming up chicken in sauna incident.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Tom Dayspring is a world-renowned expert in clinical lipidology and a previous guest on The Drive. In this episode, Tom explores the foundations of atherosclerosis and why atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death worldwide for both men and women. He examines how the disease develops from a pathological perspective and discusses key risk factors, including often-overlooked contributors such as insulin resistance and chronic kidney disease. He breaks down the complexities of cholesterol and lipoproteins—including LDL, VLDL, IDL, and HDL—with an in-depth discussion on the critical role of apolipoprotein B (apoB) in the development of atherosclerosis. Additionally, he covers the importance of testing various biomarkers, the impact of nutrition on lipid levels, and the vital role of cholesterol in brain health, including how cholesterol is synthesized and managed in the brain, how it differs from cholesterol regulation in the rest of the body, and how pharmacological interventions can influence brain cholesterol metabolism. We discuss: Defining atherosclerotic cardiovascular disease (ASCVD): development, risks, and physiological impact [2:45]; The pathogenesis of ASCVD: the silent development over decades, and the importance of early detection for prevention of adverse outcomes [10:45]; Risk factors versus risk markers for ASCVD, and how insulin resistance and chronic kidney disease contribute to atherosclerosis [17:30]; How hyperinsulinemia elevates cardiovascular risk [24:00]; How apoB-containing lipoproteins contribute to atherosclerosis, and why measuring apoB is a superior indicator of cardiovascular risk compared to LDL cholesterol [29:45]; The challenges of detecting early-stage atherosclerosis before calcification appears [46:15]; Lp(a): structure, genetic basis, and significant risks associated with elevated Lp(a) [55:30]; How aging and lifestyle factors contribute to rising apoB and LDL cholesterol levels, and the lifestyle changes that can lower it [59:45]; How elevated triglycerides, driven by insulin resistance, increase apoB particle concentration and promote atherosclerosis [1:08:00]; How LDL particle size, remnant lipoproteins, Lp(a), and non-HDL cholesterol contribute to cardiovascular risk beyond apoB levels [1:21:45]; The limitations of using HDL cholesterol as a marker for heart health [1:29:00]; The critical role of cholesterol in brain function and how the brain manages its cholesterol supply [1:36:30]; The impact of ApoE genotype on brain health and Alzheimer's disease risk [1:46:00]; How the brain manages cholesterol through specialized pathways, and biomarkers to track cholesterol health of the brain [1:50:30]; How statins might affect brain cholesterol synthesis and cognitive function, and alternative lipid-lowering strategies for high-risk individuals [1:57:30]; Exciting advancements in therapeutics, diagnostics, and biomarkers coming in the next few years [2:09:30]; Recent consensus statements on apoB and Lp(a) from the National Lipid Association (NLA) [2:12:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube