POPULARITY
Categories
El nutricionista Ignacio Lillo, resuelve dudas sobre el colesterol: qué función cumple en nuestro organismo, cuándo se convierte en un factor de riesgo y cómo podemos mantenerlo en niveles saludables. Además, explica la diferencia entre el colesterol HDL —conocido como el “bueno”— y el LDL —el llamado “malo”—, su relación con la salud cardiovascular y qué hábitos alimentarios y de estilo de vida ayudan a mantener el equilibrio.
Broadcast from KSQD, Santa Cruz on 2-26-2026: Dr. Dawn opens with an urgent measles advisory, noting the virus has an R-value of 15 compared to COVID's peak of 5, with South Carolina reporting over 1,000 cases. She recommends those who received only one MMR shot—particularly people now in their 60s—get an immune titer blood test, as protection declines after 40-50 years. Measles can cause "immune amnesia" destroying immunity to other pathogens, and rarely leads to fatal subacute sclerosing panencephalitis years later. Dr. Dawn criticizes Quest Labs' cholesterol reporting, which flags average levels as "moderate risk" with alarming red H markers even when values fall within their own stated normal ranges. She explains this creates unnecessary panic and pushes patients toward statins based on outdated 2008-2012 guidelines, when cardiology has since recognized that cholesterol can be too low. An emailer asks how an EKG can detect a past heart attack from "jagged lines." Dr. Dawn explains that each spike represents electrical signals moving toward or away from electrode pads, and a 12-lead EKG views the heart from multiple angles—smaller-than-expected spikes in specific leads indicate dead or damaged heart muscle. She urges everyone to learn CPR and AED use, which more than doubles survival chances. An emailer reports that food tastes strong on the first bite but becomes tasteless thereafter. Dr. Dawn identifies numerous medications causing taste changes including calcium channel blockers, beta blockers, statins, diuretics, and even acetaminophen. She also highlights zinc—both deficiency and toxicity above 40mg daily can impair taste, noting a zinc nasal spray was pulled from market after causing smell loss. An emailer asks about Prenuvo full-body MRI scans costing $499-1,000. Dr. Dawn cautions that while Prenuvo found 22 cancers in 1,000 people scanned, 1 in 20 scans requires follow-up biopsy and more than half are false positives—leading to stress, expense, and potential complications from unnecessary procedures. An emailer asks about seed oils after reading a Johns Hopkins article defending them. Dr. Dawn distinguishes fruit oils (olive, avocado) from industrially-extracted seed oils requiring hexane solvent, a neurotoxin that may leave residues despite claims of evaporation. She cites a BMJ study showing coconut oil raised HDL (good cholesterol) while matching olive oil's LDL impact, and recommends cold-pressed oils while avoiding hexane-extracted products, especially for infants.
Evolution Radio Show - Alles was du über Keto, Low Carb und Paleo wissen musst
Schau die Episode auf YouTube Abonniere den Kanal und verpasse keine neue Folge mehr Sponsor
How much can what you eat really influence your heart health — and how quickly can you improve your blood pressure or cholesterol through diet? In this episode of Health Matters, host Courtney Allison sits down with cardiologist Dr. Sean Mendez of NewYork-Presbyterian Brooklyn Methodist Hospital to break down the real connection between food and cardiovascular wellbeing. They explore what your health numbers mean — from blood pressure ranges to LDL cholesterol, triglycerides, HDL, and the emerging marker ApoB — and how these values signal current or future risk. Dr. Mendez explains how dietary shifts can lower LDL cholesterol by 3 to 15 percent and reduce blood pressure by several points, even without medication. He also discusses salt sensitivity, the impact of saturated fats and processed foods, and why soluble fiber, healthy fats, and whole foods can play a powerful role in improving cholesterol. The conversation dives into the DASH diet and the Mediterranean diet, outlining how each works, what they emphasize, and the evidence behind their ability to reduce blood pressure and overall cardiovascular risk. Dr. Mendez offers practical tips for getting started and key lifestyle factors that are essential for heart health. Whether you're hoping to lower your numbers, prevent future heart issues, or simply make more informed choices at the grocery store, this episode provides clear, accessible guidance on building a heart‑healthy way of eating. Chapters: 01:13 – What Do Heart Health Numbers Mean? 04:33 – How Quickly Diet Changes Improve Labs 10:59 – How to Start Changing Eating Habits Key Topics Covered What cholesterol, blood pressure, triglycerides, HDL, LDL, and ApoB measure How these numbers relate to cardiovascular disease risk Healthy ranges for blood pressure and cholesterol How diet can lower LDL cholesterol and blood pressure How quickly lab results change after modifying eating habits The role of salt sensitivity and saturated fats in heart health Foods that help lower LDL, including soluble fiber and healthy fats The DASH diet: its structure, purpose, and evidence for lowering blood pressure The Mediterranean diet: core foods, flexibility, and cardiovascular benefits Differences between DASH and Mediterranean diets Practical starting points for improving eating habits Benefits of tracking food intake and identifying patterns Easy, heart‑healthy food and snack swaps Why lifestyle factors like sleep, stress, exercise, and limiting alcohol matter Common misconceptions about eating for heart health Why heart‑healthy eating is beneficial at every age Takeaway Message Small, consistent changes to your diet and lifestyle can meaningfully improve your heart health — at any age. Understanding your numbers (like LDL, blood pressure, and ApoB) empowers you to make targeted choices, and evidence‑based eating patterns such as the DASH or Mediterranean diet can lower risk over time. Even if medications are part of your care, diet, sleep, exercise, and stress management remain essential tools for protecting your heart. Expert Guest Dr. Sean Mendez is a non-invasive cardiologist at New York Presbyterian Brooklyn-Methodist Hospital and an assistant professor of clinical medicine at Weill Cornell Medicine. His clinical interests include preventive cardiology, valvular heart disease, and cardiovascular imaging, including echocardiography, stress testing, and vascular imaging. In addition to seeing patients in his outpatient clinic, he provides inpatient care in the cardiac care unit, cardiac telemetry unit, and consultative cardiology service. Dr. Mendez is passionate about providing his patients with the highest-quality, comprehensive cardiovascular care. He addresses all aspects of health to prevent the development and progression of cardiovascular disease. Dr. Mendez, a native of Buffalo, New York, graduated magna cum laude from the University of Alabama with a bachelor's degree in both biology and mathematics. He attended medical school at the University at Buffalo, where he was inducted into the prestigious Alpha Omega Alpha Medical Society. Dr. Mendez then completed his residency in internal medicine at Massachusetts General Hospital/Harvard Medical School. He then completed his fellowship in cardiology at the Mount Sinai Hospital, where he was chief fellow. For more health and wellness news, visit NewYork-Presbyterian's Health Matters website.
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3305: Danielle Omar breaks down the essentials of omega 3 fatty acids, explaining their structure, the different types (ALA, EPA, and DHA), and why they're crucial for brain, heart, and joint health. You'll also learn which foods to prioritize and how to get enough omega 3s through simple daily choices that support overall well-being. Read along with the original article(s) here: https://foodconfidence.com/2018/11/16/everything-youve-ever-wanted-to-know-about-omega-3-fatty-acids/ Quotes to ponder: "Long story short, omega 3 fatty acids are essential polyunsaturated fats." "EPA supports your body in a ton of different ways. Getting enough EPA is super important for brain health and decreasing inflammation." "Omega 3s support heart health in some major ways! They can reduce triglycerides and blood pressure, increase HDL ('good') cholesterol, and help prevent plaque build up in your arteries." Episode references: USDA FoodData Central (Omega-3 Content of Foods): https://fdc.nal.usda.gov Recommended Daily Intake for Omega 3s (NIH): https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer Learn more about your ad choices. Visit megaphone.fm/adchoices
El aceite de oliva es mucho más que un ingrediente tradicional: es uno de los alimentos mejor respaldados por la ciencia nutricional. Hoy, Jorge Laborda presenta una nueva entrega del Quilo in Memoriam en el que el Dr. Francisco Grande Covián habla, con su propia voz y estilo, recuperados por inteligencia artificial, del aceite de oliva y de su importancia para la alimentación humana. Grande Covián ya mostró hace décadas que no todas las grasas actúan igual. El aceite de oliva, rico en ácido oleico, ayuda a reducir el colesterol LDL —asociado al riesgo coronario— sin disminuir el HDL, que cumple una función protectora. Además, contiene antioxidantes como polifenoles y vitamina E. El mensaje no es que sea un producto “milagroso”, sino que resulta beneficioso cuando sustituye a grasas saturadas dentro de un patrón saludable como la dieta mediterránea.
El aceite de oliva es mucho más que un ingrediente tradicional: es uno de los alimentos mejor respaldados por la ciencia nutricional. Hoy, Jorge Laborda presenta una nueva entrega del Quilo in Memoriam en el que el Dr. Francisco Grande Covián habla, con su propia voz y estilo, recuperados por inteligencia artificial, del aceite de oliva y de su importancia para la alimentación humana. Grande Covián ya mostró hace décadas que no todas las grasas actúan igual. El aceite de oliva, rico en ácido oleico, ayuda a reducir el colesterol LDL —asociado al riesgo coronario— sin disminuir el HDL, que cumple una función protectora. Además, contiene antioxidantes como polifenoles y vitamina E. El mensaje no es que sea un producto “milagroso”, sino que resulta beneficioso cuando sustituye a grasas saturadas dentro de un patrón saludable como la dieta mediterránea.
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3305: Danielle Omar breaks down the essentials of omega 3 fatty acids, explaining their structure, the different types (ALA, EPA, and DHA), and why they're crucial for brain, heart, and joint health. You'll also learn which foods to prioritize and how to get enough omega 3s through simple daily choices that support overall well-being. Read along with the original article(s) here: https://foodconfidence.com/2018/11/16/everything-youve-ever-wanted-to-know-about-omega-3-fatty-acids/ Quotes to ponder: "Long story short, omega 3 fatty acids are essential polyunsaturated fats." "EPA supports your body in a ton of different ways. Getting enough EPA is super important for brain health and decreasing inflammation." "Omega 3s support heart health in some major ways! They can reduce triglycerides and blood pressure, increase HDL ('good') cholesterol, and help prevent plaque build up in your arteries." Episode references: USDA FoodData Central (Omega-3 Content of Foods): https://fdc.nal.usda.gov Recommended Daily Intake for Omega 3s (NIH): https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer Learn more about your ad choices. Visit megaphone.fm/adchoices
Insulin resistance isn't just about sugar—and it's not just about weight.In this episode of Health Hacks, Tara Peterson and Dr. Jeni explain why resistance training is one of the most effective tools for improving insulin sensitivity and protecting metabolic health.Using current research and clinical insight, they break down how insulin works, why muscle is the body's largest glucose sink, and how strength training improves blood sugar control, reduces visceral fat, lowers inflammation, and slows metabolic aging—even after the workout is over.You'll also learn why up to 93% of U.S. adults are metabolically unhealthy, why muscle loss accelerates insulin resistance after age 30, and how just 2–3 strength training sessions per week can make a meaningful difference.If you're struggling with blood sugar swings, fatigue, inflammation, or stubborn weight gain—this episode is for you.
February is Heart Health Month, making it the perfect time to challenge common misconceptions about diet and cardiovascular health.One claim that always resurfaces? That ketogenic diets are bad for your heart. But when you take a closer look at the science, that assumption simply doesn't hold up.In this video, Dr. Bret Scher breaks down the real evidence behind ketogenic diets and cardiovascular risk, addressing:✅ How many “keto” studies don't actually study true ketogenic diets✅ The truth about LDL cholesterol on keto (it doesn't go up for everyone!)✅ Why triglycerides, HDL, insulin, and inflammation may matter more than LDL✅ How keto compares to DASH for blood pressure and metabolic health✅ Why saturated fat from real food behaves differently in the body✅ The critical difference between ultra-processed high-fat/high-carb diets and low-carb, whole-food ketogenic diets
Is cholesterol bad? Is low cholesterol safe? In this video, we'll cover common cholesterol misinformation, how cholesterol was demonized, and the cholesterol truth you need to know now for better health.
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
In this episode, we explore several important non-statin cholesterol-lowering therapies, focusing on their mechanisms, clinical uses, and practical considerations for patient care. We start with bile acid sequestrants, also known as resins, including cholestyramine, colestipol, and colesevelam. These medications lower LDL cholesterol by binding bile acids in the gut, prompting the liver to use more cholesterol to make new bile acids. They are effective for LDL reduction but may cause gastrointestinal side effects and have drug interaction considerations. Next, we cover niacin (vitamin B3), which can lower LDL and triglycerides while raising HDL cholesterol. While niacin was historically widely used, its role has declined due to flushing, gastrointestinal symptoms, and potential liver toxicity. Omega-3 fatty acids, including icosapent ethyl (EPA), primarily lower triglycerides and are used in patients with severe hypertriglyceridemia to reduce the risk of pancreatitis. Icosapent ethyl is a purified EPA formulation with evidence of cardiovascular benefit in select high-risk patients. Finally, we discuss bempedoic acid, a newer oral agent that inhibits ATP-citrate lyase in the liver. Because it is activated only in the liver, bempedoic acid may be useful for patients with statin-associated muscle symptoms. Common adverse effects include elevated uric acid and mild increases in liver enzymes. This episode highlights how these non-statin agents can be strategically used alone or in combination with other therapies to help patients reach their lipid goals and reduce cardiovascular risk. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources! NAPLEX Study Materials BCPS Study Materials BCACP Study Materials BCGP Study Materials BCMTMS Study Materials Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101
Today, I am excited to share the first class in a series of lipid masterclasses with the amazing Dr. Thomas Dayspring! Dr. Dayspring is certified in internal medicine and clinical epidemiology and is a fellow of the American College of Physicians and the National Lipid Association. He was previously the Educational Director of a nonprofit organization and has served as the Chief Academic Advisor for two major cardiovascular labs. Given the in-depth nature of my discussions with Dr. Dayspring over several sessions, each lasting nearly six hours, it seemed logical to present these masterclasses in segments to make them easier to understand. In our first class today, we dive into the fundamentals, exploring what lipids are and how lipids and fatty acids are classified. We cover the physiology and transport of cholesterol and the roles of apoptosis, apo-proteins, and apo-lipoproteins; we unravel the differences between HDL, LDL, IDL, and VLDL; and we explain how to calculate LDL and triglycerides to assess metabolic health. Dr. Dayspring also shares his preferences regarding lab values and indicators that help him assess the early risk of cardiovascular disease. We cover some detailed aspects of physical chemistry in this episode, so I highlight the main clinical points throughout our conversation to make it easier to follow. Be sure to join Dr. Dayspring and me for our next episode in the lipid masterclass series. IN THIS EPISODE YOU WILL LEARN: What are lipids, and why are they important? Dr. Dayspring explains what triglycerides are. How lipids get absorbed and transported throughout the body What lipoproteins are, and how they get classified How cholesterols get calculated The impact of triglycerides on cholesterol levels and cardiovascular health How high triglyceride levels can indicate early insulin resistance or increased ASCVD risk What is the role of HDL particles? How metabolic syndrome impacts cardiovascular health Bio: Thomas Dayspring MD is a Fellow of both the American College of Physicians and the National Lipid Association and is certified in internal medicine and clinical lipidology. After practicing in New Jersey for 37 years, he moved to Virginia in 2012. He served as an educational director for a nonprofit cardiovascular foundation and, until mid-2019, as a Chief Academic Advisor for two major CV laboratories. Since then, he has served as a virtual cardiovascular / lipidology educator. Career-wise he has given over 4000 domestic (in all 50 states) and several international lectures, including over 600 CME programs on atherothrombosis, lipids/lipoproteins (and their treatment), vascular biology, biomarker testing, and women's cardiovascular issues. He has authored several manuscripts and lipid textbook chapters and performed several podcasts. For several years, he was an Associate Editor of the Journal of Clinical Lipidology. He was the recipient of the 2011 National Lipid Association's Presidents Award for services to clinical lipidology and the 2023 Foundation of NLA Clinician/Educator Award. He has over 34K followers on his educational Twitter (X) feed (@Drlipid). He has Gold Heart Member status as a professional member of the American Heart Association and serves as a Social Media Ambassador for the European Atherosclerosis Society and the National Lipid Association. Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow) Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Thomas Dayspring Twitter (@DrLipid) LinkedIn Books written by Gary Taubes
Try Fitness Lab to get personalized daily coaching on nutrition, training, and biofeedback that adapts to how you want to train, whether you're focused on lifting, endurance, or both. Get 20% off through February 17:http://bit.ly/fitness-lab-pod20--You've been told cardio is for a healthy heart and lifting weights is for building muscle. But what if strength training is itself a form of cardio?What if you're ignoring one of the most effective tools for lowering blood pressure, improving cholesterol, and reducing your risk of heart disease?Philip breaks down the evidence showing that strength training lowers blood pressure on par with first-line medication, improves HDL and LDL cholesterol, enhances insulin sensitivity, and reduces visceral fat, all independent of cardio. You'll learn why your muscle tissue functions as a metabolic organ that regulates blood sugar, why adults who lift have up to 17% lower cardiovascular disease risk, and how to program your lifting sessions to get a real cardiovascular training effect without adding time on the treadmill. Philip also answers listener Jack R.'s question comparing cardio and lifting head-to-head for fat loss, muscle building, and long-term sustainability after 40. Whether you're already strength training over 40 or still treating the weight room as optional for heart health and longevity, this episode gives you the evidence-based case for making lifting your foundation.Timestamps:0:00 - Why "cardio for your heart" is incomplete 1:43 - The 2023 AHA statement about lifting weights and heart health 5:28 - How strength training lowers blood pressure as much as medication 7:11 - Nitric oxide, arterial stiffness, and improved blood vessels 9:27 - Cholesterol, triglycerides, and ApoB improvements 13:17 - Why muscle is your most powerful metabolic organ for insulin and blood sugar 15:20 - Cardio vs. lifting for fat loss and building muscle after 40 18:01 - Visceral fat, inflammation, and menopause 19:47 - Can lifting weights improve VO2max? 22:01 - Longevity data and the minimum dose of strength training for heart health 23:57 - How to get cardiovascular benefits WITHOUT extra cardio 26:04 - Rest periods, compound movements, and rep ranges for heart-healthy lifting 28:59 - Weekly template combining strength training and walking 30:59 - Physical reserve and why strength protects your heart all day 33:04 - Bonus: 10-second heart rate recovery test you can do between sets
Cholesterin wurde lange Zeit auf gutes HDL- und schlechtes LDL-Cholesterin reduziert – dass diese Sicht zu kurz greift, belegt aktuelle Forschung. In dieser Episode spricht Priv.-Doz. Dr. med. habil. Katharina Lechner vom Helmholtz Zentrum München über einen Marker, der das kardiovaskuläre Risiko präziser abbilden kann als LDL-Cholesterin allein: Apolipoprotein B (ApoB). Wir besprechen, - warum eine Messung der Anzahl aller ApoB-Partikel das individuelle Herz-Kreislauf-Risiko genauer widerspiegelt als klassische Cholesterinwerte. - wieso genetisch bedingte Fettstoffwechselstörungen durch einen gesunden Lebensstil nicht ausreichend kontrollierbar sind. - wann eine medikamentöse Therapie sinnvoll ist – und welche modernen Behandlungsmöglichkeiten zur Verfügung stehen. - warum Lipoprotein(a) als eigenständiger Risikofaktor mindestens einmal im Leben gemessen werden sollte. - welche Rolle die Ernährung, regelmäßiges Krafttraining und Schlaf in der Prävention spielen. Katharina Lechner erklärt, wie moderne Medizin Risiken frühzeitig sichtbar machen kann, lange bevor Symptome auftreten. Die renommierte Kardiologin und Forscherin mit Schwerpunkt auf Lipidologie und personalisierter Prävention zeigt, wie patientenzentrierte, datenbasierte und lebensbegleitende Strategien unsere Gefäßgesundheit langfristig schützen können."Der ERCM Medizin Podcast" Social & Webseite:Instagram: https://www.instagram.com/ercm.podcast/ TikTok: https://www.tiktok.com/@ercm.podcast?lang=de-DE Webseite: http://www.erc-munich.com Kontakt: podcast@erc-munich.comPrivatdozentin Dr. med. Katharina Lechner:Helmholtz Zentrum München: https://www.helmholtz-munich.de ("https://www.helmholtz-munich.de")Über das ERCM:Im Europäischen Radiochirurgie Centrum München (ERCM) setzen wir seit über 20 Jahren auf präzise Tumortherapien: hochmoderne Radiochirurgie und innovative Medizintechnologien zur gezielten und schonenden Behandlung verschiedener Tumoren – gutartige Neubildungen ebenso wie schwere Krebserkrankungen. Jahr für Jahr schenken uns mehr als 1.000 Patientinnen und Patienten ihr Vertrauen auf dem Weg zu einer individuell abgestimmten Therapie. Unser Ziel: Personalisierte, präzise und vor allem patientenzentrierte Behandlungen, die auf eine effektive und nebenwirkungsarme Therapie bei guter Lebensqualität fokussieren.(00:00:00) Intro(00:00:50) ApoB: Der wichtigste Marker für Herz-Kreislauf-Risiko(00:07:24) Warum ApoB nicht im Standard-Labor ist(00:09:50) Normalwerte vs. Idealwerte: Der größte Blindspot(00:18:04) Deutschland im europäischen Vergleich: Letzter Platz(00:19:23) Genetische vs. erworbene Fettstoffwechselstörungen(00:54:48) Lipoprotein(a): Der vergessene Risikofaktor(00:32:25) Cardio-CT: Plaques sichtbar machen(00:42:07) Statine: Wirkung, Nebenwirkungen und richtige Dosierung(00:46:00) Neue Therapien: Von Antikörpern bis CRISPR(01:11:22) Ketogene Ernährung: Lean Mass Hyper-Responder(01:01:21) Lebensstil: Die 95-Prozent-Regel für Gesundheit(01:09:01) CORA Digital Fit: Personalisiertes Coaching(01:21:14) Take-Home-Message: Die drei wichtigsten Werte#Cholesterin #ApoB #LipoproteinA #Herzinfarkt #Schlaganfall #Prävention #Statine #Lipidstoffwechsel #CardiovaskuläreGesundheit #Fettstoffwechsel #HerzKreislauf #ERCMPodcast #KatharinaLechner #PCSK9 #Kardiologie
On this episode of Vitality Radio, Jared takes a closer look at the cholesterol conversation and the widespread use of statin medications through a functional health lens. Rather than relying on fear or headlines, he explores how cholesterol numbers are interpreted, the difference between risk markers and root causes, and why metabolic health, inflammation, and lifestyle factors may play a larger role in long-term heart wellness. Jared also explains concepts like absolute risk, number needed to treat (NNT), and why informed decision-making matters when evaluating any health strategy. This episode encourages listeners to ask better questions, seek clarity, and consider a comprehensive approach to cardiovascular health that includes nutrition, movement, and targeted supplementation. As always, this discussion is educational and designed to empower you with information so you can make the best decisions for your personal health journey.Products:N.O. Cardio BoostVital 5 Omega-3 + AntioxidantsNatural Factors Rx Omega-3Natural Factors BerberineSolaray BerberineVital 5 Magnesium BisglycinateAdditional Information:#563: Bad Medicine: Why Your Gallbladder Isn't Disposable & How to Thrive With or Without It #332: Cholesterol Controversy - Jared's Interview on Inside The Aisle with Niki WolfeDr. Aseem MalhotraDr. Uffe RavnskovDr. Zoë HarcombeDr. Malcolm KendrickDr. David DiamondVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
Protect Your Brain: Sleep, Stress, Cholesterol & Stroke Risk. In this powerful brain health podcast, Dr. Prasanna Karki, Neurosurgeon, Neurointerventionist, and Biohacker, explains everything you need to know about stroke prevention, brain aneurysm, and long-term brain health. We break down what is stroke, aneurysm symptoms, and how early stroke diagnosis can save lives. Dr. Karki discusses smoking effects on brain health, vaping vs cigarettes health risks, alcohol brain damage, and whether brain damage recovery is possible. He reveals the truth about coffee brain health, stress and brain health, sleep and brain function, and how cholesterol levels like LDL vs HDL cholesterol affect blood pressure and stroke risk. We also explore fish oil brain benefits, healthy habits for brain longevity, and practical ways to prevent brain stroke before it happens. If you want to protect your brain, understand aneurysm symptoms, and reduce your stroke risk, this episode is a must-watch. Whether you're concerned about blood pressure and stroke, want clarity on biohacking brain health, or simply want to build better daily habits for your brain, this conversation delivers science-backed insights you can apply immediately. GET CONNECTED WITH Dr. Prasanna Karki: LinkedIn - https://www.linkedin.com/in/prasanna-karki-138bb8153 Facebook - https://www.facebook.com/profile.php?id=61556672974094# Instagram - https://www.instagram.com/prassuk/ TikTok - https://www.tiktok.com/@prassuka
HEALTH NEWS A Simple Diet Change Could Slow Liver Cancer Brief, intensive exercise helps patients with panic disorder more than standard care Lucid dreaming could be used for mental health therapy, new study says US cancer institute studying ivermectin's ‘ability to kill cancer cells Too many saturated fats may be more harmful than too many refined carbohydrates. Clips Andrew Bridgen - https://x.com/ABridgen/status/2020573528571977993?s=20 MAHA Alliance Mike Tyson Super Bowl Commercial - https://www.youtube.com/watch?v=jg1SjFt1a_U KETO DIET RISKS The rationale for Keto Diet by its advocates Restricting carbohydrates, suppressing insulin and ketosis will lead to better metabolic heath, increase weight loss, reduce inflammation, and protect from chronic diseases. Keto Claim: Carbohydrates raise insulin leading to fat storage – keto lowers insulin and burns body fat better Debunking: Ketosis is a metabolic state and not a health outcome. For example ketones can be elevated by very long fasting, starvation, different illnesses and uncontrolled diabetes. Keto Claim: By minimizing carbs keto stabilizes blood sugar, reduce insulin spikes, and improve insulin sensitivity that benefits those with type 2 diabetes Debunked: This claim contradicts the evidence of induced hepatic insulin resistance and glucose intolerance in longer-term studies. In animal models, keto diets impair blood sugar regulation within several days, which shows harm for metabolic health. Keto Claim: Ketones are seen as “clean” fuel that advocates claim are anti inflammatory and neuroprotective. Believe that this along with ketosis lowers triglycerides, raises HDL cholesterol, and improves lipid profiles. They argue that the increase in LDL cholesterol is benign. Claim saturated fats are harmless if carbs are low Debunked: This claim is undermined by the increased LDL cholesterol, triglycerides, and cardiovascular risks from saturated fats in animal products. Meta-analyses show no long-term lipid improvements from keto diets. Rather this is the risk in elevated low-density lipoprotein and very-low-density lipoproteins that increase cardiovascular disease Also, insulin reduction does not override the quality of fat. LDL cholesterol and ApoB, as well as atherosclerosis, increase significantly on an animal based diet. Saturated fat still remains a causal factor for cardiovascular disease. Keto Claim: High protein and fat increases satiety and therefore reduces hunger Debunking: Weight loss is primarily from reduced intake due to satiety, not fat-burning efficiency. Long-term keto adherence often leads to weight regain with no significant sustained benefits for visceral fat or appetite control. hort term weight loss is not same as long term benefits. A study shows that weight loss at 3-6 months on a keto diet disappears by 12 months Keto Claim: It enhances brain function and energy that then improves mental clarity and mood. Argue that animal products like eggs and organ meats provides choline and other nutrients for brain health. Debunked: There is no strong evidence for this claim. In fact keto's nutrient deficiencies and lack of fiber in the long term can lead to fatigue, constipation and in women neural tubal defects. Keto's claims are only based on short term trials. Keto Claim: Use the evolutionary argument that humans evolved eating meat and fat – same argument the paleo folks used. Therefore, they believe keto diets align with human biology Debunked: A big study in Science in 2025 analyzed tooth enamel from skeletons of some of our oldest human ancestors, 3.5 million years ago, and found they ate predominately a plant based diet with no substantial sigh of mammalian meat. The isotopes matched herbivores (fruits, leaves and grasses, tubers, nuts, other vegetation) not carnivores. Keto Diet Risks It is worth noting, according to the Northwestern University Health site, there is a sizable drop out rate of participants in keto trials. Although, there are studies that show keto does what it claims in the short term, there are no long-term human data to support their claims that an animal-based diet does this efficiently. Important, research leans in the direction to indicate that keto's benefits – especially weight loss and glucose reduction, are transient and may not be directly related to animal food consumption itself but rather to calorie reduction and limiting glycogen. Long term prospective studies and systematic meta analysis evaluations consistently show high red meat consumption, full-fat dairy and animal fats are associated with the following medical conditions. This is true even when carbohydrate intake is low A good thorough study in JAMA shows that unprocessed red meat mildly increases all cause mortality – about 3-5% per 100 grams meat per day High red and processed meat consumption increases carcinogenic N-nitroso compounds and heterocyclic amines that raise cancer risks by up to 18% per 50-100 grams/day – from meta analysis in the European Journal of Epidemiology Dairy increases IGF-1 levels thereby too much calcium also suppressing Vitamin D and elevating prostate cancer risks by 79% per 400 gram dairy per day. Worse for processed meats that inreases risk by 21% per 20 grams/day – American Journal of Epidemiology Red meat is linked to hormonal disruptions and carcinogens contributing breast cancer – European Journal of Cancer Total unprocessed red meat consumption shows a modest 5% risk in pancreatic cancer per 100 grams/day. – From journal Clinical Nutrition Many meta-analyses on meats have a relationship to stomach/gastric cancer, but processed meats are worse than unprocessed red meat. From study in Nutrients – 24 studies showed unprocessed red meat associated with gastric cancer by about 25% increase risk for every 100 grams/day. Unprocessed red meat is linked to an 11% higher risk in overall cardiovascular disease risk due to inflammation and endothelial dysfunction. – from European Heart Journal Saturated fats in meats increases non-HDL cholesterol and blood pressure and raises the risks of ischemic heart disease by 119% per 100 grams/day red meat – from American J Clinical Nutrition Red meat diets reduce LDL Cholesterol much less than plant proteins and thereby increase atherosclerosis risks – from the journal Circulation Red meats (an processed meats also in this study) contributes to insulin resistance via heme iron and raises Type 2 diabetes risks by up to 51% per 50 grams/day – International Journal Environmental Research in Public Health Saturated fats in unprocessed red meat has a modest positive 12% increase with stroke risk – From European Heart Journal Unprocessed poultry consumption shows a modest 4% increase in incident cardiovascular events per 100 grams/day. This is believed to be due to arachidonic acid poultry – in JAMA Red meat contributes to sodium and saturated fat intact raising hypertension conditions by 14% per 50-100 gram/day – from journal Advanced Nutrition Saturated fats from animal products cause lipotoxicity and insulin resistance, that promotes hepatic fat accumulation leading to non-alcoholic fatty liver disease – from Cardiovascular Development and Disease High animal protein increases urinary calcium and acid overload leading to the formation of kidney stones – from the journal Nutrient Animal-heavy diets have low fiber and micronutrient intake that contribute to nutrient deficiencies. Also causes constipation that can lead to immune system issues. – from the journal Nutrients Red meat, dairy, and eggs disrupts the gut metabolism of carnitine and choline. This promotes TMAO plaque formation and inflammation that leads to atherosclerosis. – from Journal of Cardiovascular Development. Although unprocessed meat consumption has not been adequately associated with dementia and Alzheimer's – yes, processed meats do – there are studies showing red meat is associated with “subjective cognitive decline” (SCD) which is related to precursors to dementia and Alzheimer's. A study in journal Neurology links unprocessed red meat eaten at 1 or more servings per day to 16% higher risk in SCD. High caloric density from saturated animal fats displaces fiber that contributes to weight gain obesity. From Neal Barnard in the American Journal of Clinical Nutrition Animal products transmit prions that are associated with neurodegenerative disorders. Proinflammatory compounds like TMAO are linked to neurological risks. – in International Journal of Molecular Science
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Fibrate derivatives are lipid-lowering medications that primarily target triglycerides rather than LDL cholesterol. Common agents include gemfibrozil, fenofibrate, and fenofibric acid. While their use has declined with the widespread adoption of statins, fibrates remain an important option for patients with severe hypertriglyceridemia, particularly to reduce the risk of acute pancreatitis rather than for routine cardiovascular risk reduction. Fibrates work by activating PPAR-alpha, which increases lipoprotein lipase activity and enhances the clearance of triglyceride-rich lipoproteins. This leads to significant reductions in triglycerides, modest increases in HDL cholesterol, and variable effects on LDL cholesterol. Because they are not strong LDL-lowering agents, fibrates should not replace statins in patients who require LDL reduction, but they can be effective in select clinical scenarios when triglycerides are the primary concern. From a safety standpoint, fibrates are generally well tolerated but require careful monitoring. Common concerns include gastrointestinal side effects, liver enzyme elevations, gallstone risk, and muscle toxicity, especially when combined with statins. Gemfibrozil carries a higher risk of drug interactions, while fenofibrate is usually preferred if combination therapy is necessary. Appropriate patient selection, lab monitoring, and lifestyle counseling are essential to maximize benefit and minimize harm when using fibrate derivatives. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources! NAPLEX Study Materials BCPS Study Materials BCACP Study Materials BCGP Study Materials BCMTMS Study Materials Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101
Send us a textDr. H. Jackson Downey sits down with MedEvidence!™ to give the low-down on keeping your lipoprotein(a) numbers down. Lipoprotein little a, also called Lp(a), is a really, really, really, really, really bad cholesterol that is genetically determined, meaning exercise and diet don't help lower the numbers. Instead, Dr. Downey explains, clinical trials are looking into investigational medications for this bad type of cholesterol. Dr. Downey describes the ins and outs of Lp(a) and how clinical research is our best bet for solutions to this dangerous cholesterol.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!
For decades, we've been told that high cholesterol is the main driver of heart disease—and that lowering LDL should be the primary goal. But as science has evolved, so has my thinking. In today's Office Hours, I explain why cholesterol alone doesn't tell the full story, what most doctors still aren't testing, and what's really driving heart disease for the majority of people. Today we discuss: • Why many people have heart attacks despite “normal” LDL cholesterol • The difference between cholesterol levels and cholesterol particles • How inflammation and insulin resistance fuel heart disease • Why sugar and refined starches are more dangerous than fat • The most important labs to assess real cardiovascular risk • What ApoB, lipoprotein(a), and triglyceride-to-HDL ratio reveal about your health • How metabolic dysfunction—not cholesterol alone—drives plaque buildup Heart disease is far more complex than a single lab value. When you understand the role of metabolic health, inflammation, and the right biomarkers, you can take meaningful steps to protect your heart and long-term health. Visit functionhealth.com for 160+ lab tests at just $365 a year. Helpful Resources: Join the 10-Day Detox to Reset Your Metabolic Health https://drhyman.com/pages/10-day-detox Have a question you'd love answered on Office Hours? Submit it here
Beat Heart Disease Before It Starts — Insights from Dr. Howard Elkin with Dr. Ben Weitz. Dr. Elkin's website is Heartwise.com. His main office is in Whittier, California and he has a concierge practice in Santa Monica, California and his office number is 562-945-3753. What You'll Hear In This Episode: 02:40 A Functional Medicine approach looks at why the body would lay down plaque as a rational response to coat the artery wall against inflammation or oxidation or glycation reactions. 06:08 I asked Dr. Elkin what his view is on cholesterol and he mentioned that half of patients who have heart attacks have normal cholesterol 08:09 Dr. Elkin discusses the benefits of the Boston Heart Lab and other advanced lipid profiles for better assessing true CVD risk 09:36 Howard explains how small, dense particles are more likely to be oxidized and incorporated into arterial plaques 10:50 I explained how larger HDL particles perform reverse cholesterol transport to remove potentially harmful LDL particles from the blood stream 11:02 I asked how Dr. Elkin treats patients who have small, dense LDL particles and he explained that he gets his patients to change their lifestyle and he uses certain nutritional supplements such as niacin before he puts them on medications. 13:10 I asked Howard what are some of the most important dietary factors to change to lower cardiovascular risk in such a patient? He said it's not about cutting our eggs and saturated fat, like we used to think. Howard's way of thinking is that sugar not fat is the main villian, since it is pro-inflammatory. 16:57 I asked Dr. Elkin about one of his recent blog articles where he wrote about the new PCSK-9 inhibitor medications for cholesterol. Dr. Elkin explained these may be effective, but they showed that they could bring LDL cholesterol levels down to 36 and this is actually not a good thing, since you need cholesterol for hormones, vitamin D production, and brain function. Also, these drugs cost $14,000 per year. 20:30 Howard explained that when he does places patients on statins, he always puts them on CoQ10 to prevent muscle problems. He usually uses 100-200 mg to start with. With patients who have heart failure he will use very high dosages, along with magnesium, L-Carnitine, and D-Ribose. 24:22 Dr. Elkin discusses what nutritional supplements he will use to raise HDL levels: 2 tablespoons daily of Extra Virgin Olive oil, coconut oil, low carb diet, exercise, weight reduction, and niacin. 27:52 I asked Howard how to lower Lp(a). He said that this fragment of LDL is extremely atherogenic and is highly likely to get oxidized. Niacin, estrogen, and fish oil can help. I mentioned that I also found that berberine and tocotrienols were also helpful. 30:30 We discussed what to do about patients with elevated CRP (indicative of inflammation). Dr. Elkin mentioned that this test should be done routinely on all patients, but it is often not measured. There is a link between obesity and CRP and also between oral cavity problems and sinusitis and even poor sleep. He likes fish oil, turmeric, ginger, and boswellia to reduce inflammation.
Við fjölluðum um blóðfitu, eða kólesteról, í þættinum í dag og til okkar kom hjartalæknirinn Hilma Hólm. Há blóðfita er áhættuþáttur hjarta- og æðasjúkdóma og þeir eru algengasta dánarorsök Íslendinga. Þessir sjúkdómar gera miklar kröfur til heilbrigðiskerfisins enda er meðferð oft flókin og kostnaðarsöm. Í þessu samhengi er oft talað um „vonda kólesterólið“ (LDL) og „góða kólesterólið“ (HDL). Að hluta til er há blóðfita arfgeng, því geta tveir einstaklingar sem lifa á nákvæmlega sama mataræði og hreyfa sig jafnmikið haft gjörólíkar blóðfitur. Mikið hefur verið fjallað um mataræði og blóðfitur á undanförnum árum og hvað er rétt og hvað er rangt. Sumir segja að blóðfitulækkandi lyf séu ofnotuð á meðan aðrir segja að þetta séu lífsnauðsynleg lyf. Hilma fór með okkur yfir þetta í dag. Út eru komin hreyfispjöld til heilsueflingar. Þetta eru 50 einfaldar og fjölbreyttar styrktar- og liðleikaæfingar sem auka kraft, þol og jafnvægi. Hverri æfingu fylgja myndir og skýrar leiðbeiningar. Æfingarnar eru framkvæmdar án áhalda og þær er hægt að gera hvar sem er og henta fólki á öllum aldri. Höfundarnir eru Anna Björg Björnsdóttir og Gerður Jónsdóttir, íþrótta- og heilsufræðingar og afrekskonur í íþróttum, þær komu í þáttinn í dag. Og lesandi vikunnar í Mannlega þættinum í þetta sinn var Margrét Eggertsdóttir rannsóknarprófessor á menningarsviði hjá Árnastofnun. Hún sagði okkur frá því hvaða bækur hún hefur verið að lesa undanfarið og hvaða bækur og höfundar hafa haft mest áhrif á hana í gegnum tíðina. Margrét talaði um eftirfarandi bækur og höfunda: Fóstur e. Claire Keegan, þýðandi: Helga Soffía Einarsdóttir. Með minnið á heilanum e. Þórhildi Ólafsdóttur Jeg vil: en forfatters portræt af Sigrid Undset (1882–1949) e. Idu Jessen Hamingjudagar heima í Noregi e. Sigrid Undset, þýðing úr ensku á íslensku Brynjólfur Sveinsson Allt sem við hefðum getað orðið e. Sif Sigmarsdóttur Tónlist í þættinum í dag: Meira, meira / Ríó tríó (Gunnar Þórðarson, texti Jónas Friðrik Guðnason) Crossroads / Helgi Jónsson & Emilíana Torrini (Emilíana Torrini, Helgi Jónsson og Philipp Steinke) High Sierra / Linda Ronstadt (L.Harley Allen) UMSJÓN: GUÐRÚN GUNNARSDÓTTIR OG GUNNAR HANSSON
A dislipidemia deixou de ser um tema restrito a “colesterol alto” e a Diretriz Brasileira de 2025 veio para deixar bem claro que o foco é prevenção da aterosclerose e suas repercussões em desfechos cardiovasculares!No DozeCast #208, Victor Bemfica e Diandro Mota discutem os principais destaques da nova diretriz e o que, de fato, muda na prática clínica.Falamos sobre:• Atualizações na estratificação de risco e tomada de decisão clínica• Metas lipídicas e marcadores adicionais (não-HDL, ApoB, Lp(a))• Estratégias de tratamento: intensificação precoce e terapias combinadas quando indicado• Papel das terapias hipolipemiantes modernas: anti-PCSK9, inclisiran, ácido bempedoico, entre outras • Condutas em populações específicas (diabetes, DRC, idosos e alto risco)
Join My Private Group: https://theaxioncollective.manus.space/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In today's episode, I'm finally circling back to one of my favorite research compounds that I don't talk about nearly enough: Cardarine (GW501516). I've used it for years in a cycled on, cycled off way, because when it works, it really works. The two big reasons people care about Cardarine are simple. Endurance and lipids.I break down why endurance athletes love it, why it makes cardio feel almost effortless for me within a week or two, and why it's not “a stimulant fat burner,” but can still absolutely support a fat loss phase when your training and diet are dialed in. Then we get into the science. I walk you through the background, how it was developed as an “exercise in a pill,” and the human trial data showing improvements in HDL, triglycerides, ApoB, liver fat, and insulin markers.And yes, we address the elephant in the room: the rodent cancer findings, the lack of long-term human data, and how I personally think about risk, dosing, and cycling. I'm not here to tell you what to do. I'm here to give you the data, how I interpret it, and let you make an informed decision.Also, at the end, I tease another compound you may want me to cover next: GW0742.
Imagine a humble bulb, small enough to fit in the palm of your hand yet potent enough to ward off ancient evils, heal ailments, and elevate a dish from mundane to divine. This is garlic, Allium sativum, a culinary and medicinal titan woven into the fabric of human history for over 5,000 years. From ancient Egypt's sunbaked fields to modern-day China's bustling markets, garlic has been revered, feared, and savored across cultures. Its pungent aroma and sharp bite belie a treasure trove of health benefits, a few drawbacks to be aware of, and a dazzling array of varieties that paint the world in shades of white, purple, and pink.Garlic's story begins in the cradle of civilization, where it was more than just food—it was medicine, currency, and even a spiritual shield. Ancient Egyptians fed it to laborers building the pyramids, believing it boosted stamina. At the same time, Sanskrit texts from 5,000 years ago document its use in treating heart disease and arthritis. The Greeks fed garlic to athletes before the earliest Olympics.In medieval Europe, garlic was hung over doorways to repel vampires and evil spirits. Today, science has caught up with folklore, confirming what our ancestors intuited: garlic is a nutritional powerhouse. Its magic lies in its sulfur compounds, particularly allicin, which forms when a clove is chopped, crushed, or chewed. This volatile compound, responsible for garlic's signature smell, is a key player in its health benefits, acting as an antioxidant, anti-inflammatory, and antimicrobial agent.Research shows that garlic can lower total cholesterol and LDL ("bad" cholesterol) by up to 10% in individuals with slightly elevated cholesterol while increasing HDL ("good" cholesterol). Compounds like ajoene improve blood flow, prevent clots, and reduce the risk of heart attacks and strokes. It is high in antioxidants, such as allicin, which combat oxidative stress linked to aging and diseases like Alzheimer's. Additionally, garlic possesses well-known antibacterial and antiviral properties, often called "Russian penicillin."With over 300 varieties, garlic is as diverse as the cultures that cultivate it. The two main types are hard neck (Allium sativum var. ophioscorodon) and soft neck (Allium sativum var. sativum). Hard-neck garlic, with its rigid central stalk, thrives in colder climates and produces fewer, larger cloves with complex flavors. Varieties like Rocambole, with its rich, nutty taste, and Purple Stripe, sporting vibrant purple streaks, are prized by chefs for their depth. Read the Full Content HereMore PodcastsProduced by Chef Walters SimVal Media Group, USA
I was shocked at the comments on this post. Many people, some of them I know to be smart, thought I was nuts for suggesting two middle-aged women who had isolated high LDL-C needn't take meds because their calculated 10-year risk was less than 3% What shocked me is that our guidelines suggest treatment with statins when 10-year risk is ≥ 7.5%. You may not know this but clinicians are supposed to consider cholesterol (and BP) based on overall risk, which include things like age, blood pressure, smoking status as well as HDL. Here is a link to the PCE. It drives me bananas that clinicians don't go over this with patients. They just look at LDL-c in isolation. Content like this comes free of industry support. Please consider becoming a free or paid subscriber.Experts chose this a 7.5% threshold because they felt it was the point where the absolute risk reduction from statins (about 20-25% relative risk reduction) for nonfatal cardiac events outweighed any potential downsides of statins. It is an arbitrary threshold. The thinking: We know from many RCTs that statins reduce future risk by about 20-25% over 5 years. So .25 x the estimated risk outputs the absolute risk reduction. Let's say a person has a calculated risk of 10%. They can expect a 2.5% risk reduction (.25 x 10% = 2.5%) over 10 years. But .25 x 3% = .75, so a person with an estimated risk of 3% who takes a daily pill for 10 years goes to 2.25%. That's not much. Here are some pics of the pushback I recieved:My colleagues rightly point out that atherosclerosis of the coronary arteries is a slow process and longer exposure to lower LDL-c is beneficial. They feel that the 10-year horizon is too short. They cite something called Mendelian randomization studies which find that people who were born with genetic profiles that cause low cholesterol also have low rates of heart attacks. I wrote a post about this. I actually think that statins and blood pressure drugs may have greater effects in younger people who are at lower risk. But come on. Both individuals who I helped calculate risk were below 3%. That's too low to worry about. Further, if you think we treat people with elevated LDL levels who have this low of a risk, why do we need risk calculators? Or…why don't we just treat everyone above a certain age, since age is the largest driver in the calculators? These are issues I spoke with Drs Foy and Murthy about. I learned a ton. I hope you will too. Topics include:* The value of risk calculators* The uncertainty of prediction* The best time window to consider (statin trials were for 5 years; can we assume effect sizes over 5 years are similar at 30 years?) * The causal role of LDL-c vs “metabolic health”* The value of coronary artery calcium testing * Lipoprotein (a) Academic people like to make fun of podcasts, but I can't imagine a more educational 40 minutes. Andrew and Venk are two of the most thoughtful people in cardiology today. Enjoy and consider supporting Sensible Medicine This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe
Join Angela and Dr William Li for a look at the complex world of heart health and hormonal shifts, in which they tackle the often-confusing link between menopause and rising cholesterol levels, debunking common myths and providing clarity on the real risks of high LDL. Dr. Li shares his expert insights on the nuances of heart disease prevention, the importance of blood sugar balance, and how a holistic, evidence-based approach can help you navigate these sudden health changes with confidence and balance. KEY TAKEAWAYS: High LDL cholesterol is linked to an increased risk of cardiovascular disease because it can build up as plaque in the arteries and impede blood flow. Total cholesterol levels are no longer the primary indicator of heart disease risk; instead, doctors focus on the ratio of "good" HDL to "bad" LDL cholesterol. While some people have genetic predispositions to extremely high cholesterol, modern medicine emphasises a more nuanced understanding of different cholesterol components. Maintaining blood sugar balance is crucial, but health influencers often exaggerate the dangers of minor "spikes" and "crashes" that are actually normal bodily functions. TIMESTAMPS AND KEY TOPICS: 0:45 How LDL cholesterol sticks to artery walls like "Velcro," 1:42 How medical understanding has evolved from tracking total cholesterol to focusing on HDL/LDL ratios. 3:07 The influence of health influencers on public anxiety regarding blood sugar and cholesterol levels. 4:03 Importance of "homeostasis" and how the body naturally strives for balance in its systems. VALUABLE RESOURCES Join The High Performance Health Community Click here for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. CONTACT DETAILS Instagram Facebook LinkedIn Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast. This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/
In this episode, Dr. Jockers breaks down the five most important lab tests that reveal how well your heart, brain, metabolism, and longevity systems are functioning. You'll learn why standard lab work often misses early warning signs. These markers help identify risk long before symptoms appear. You'll see how fasting insulin, hemoglobin A1C, and the triglyceride to HDL ratio expose whether your body is stuck in sugar burning or efficiently using fat for fuel. Dr. Jockers explains what optimal ranges actually mean. These labs paint a clear picture of metabolic health. Homocysteine and C-reactive protein reflect inflammation, cardiovascular stress, and brain aging. Dr. Jockers explains how elevated levels connect to long-term disease risk. These markers offer critical insight into overall longevity. In This Episode: 00:00 Understanding Hemoglobin A1C 00:24 Introduction to Top Lab Tests 03:18 Top 5 Lab Tests for Health and Longevity 04:21 Fasting Insulin Levels: The Superhero Hormone 06:43 Hemoglobin A1C: Blood Sugar Regulation 08:36 Triglycerides to HDL Ratio: Metabolic Health 12:03 Homocysteine: The Inflammatory Amino Acid 15:18 C-Reactive Protein: Inflammation Marker 18:10 Diet and Lifestyle for Optimal Health 21:04 Conclusion and Final Thoughts Hair loss isn't caused by age but by hair follicles being switched off, and Swiss researchers discovered how to turn them back on with Purality Health - AnaGain Nu, a clinically proven compound extracted from pea sprouts that stimulates hair follicle cells and pushes them back into the growth phase. Purality Health combines AnaGain Nu with their advanced MyCell liposomal delivery system to maximize absorption and effectiveness. They are currently offering a Buy One, Get One Free deal, backed by a 180-day money-back guarantee, giving you six full months to try it risk-free. To claim this exclusive offer and support healthier hair growth, visit https://renewyourhair.com/drj If you're looking for an easy way to hit your protein goals without sacrificing quality, Huel's Black Edition delivers 35–40 grams of clean, plant-based protein along with essential vitamins and minerals—perfect for busy mornings, post-workout fuel, or a quick, filling meal. Their ready-to-drink bottles and versatile powder make it simple to stay nourished without prep or guesswork. New customers can get 20% off Huel's high-protein starter kit by visiting huel.com/jockers. "A healthy fasting insulin level should be under 6. Elevated insulin means you're storing fat, not burning it." ~ Dr. Jockers Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Visit renewyourhair.com/drj to try AnaGain Nu with a buy one, get one free offer and a 180-day money-back guarantee. Visit huel.com/jockers for 20% off Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
In der 139. Folge des Goodcast Deepdive geht es um Fett. Um genau zu sein um Transfette und ihr leises Verschwinden aus unseren Lebensmitteln. Christian und Julius fragen sich, warum etwas, das jahrelang völlig normal war, heute kaum noch auftaucht. Transfette steckten in Pommes, Gebäck und Fertigprodukten. Heute sind sie fast weg. Wer hat das entschieden? Aus Gesundheitsgründen oder weil sich Regeln geändert haben? Und was heißt das für das, was wir täglich essen? Ein zentraler Fakt: Industriell hergestellte Transfette erhöhen das LDL-Cholesterin und senken gleichzeitig das HDL, wodurch das Risiko für Herz-Kreislauf-Erkrankungen steigt. Eine Folge für alle, die wissen wollen, was wirklich im Essen steckt und warum sich Rezepturen verändern, ohne dass wir es an der Kasse merken. Eine Produktion von MAKIKO* für die Viva Equality gemeinnützige UG Gastgeber: Julius Bertram Mitarbeit: Tilman Perez Produktion: MAKIKO*
When Dave Feldman first walked into a LowCarbUSA® event in 2016 carrying a laptop full of lab results, few people could have predicted where that moment would lead. "I'm approaching everyone with my computer," Feldman recalls, "because I'm doing these self-experiments—getting blood work—and I'm trying to figure out why my cholesterol numbers were doing what they were doing." What started as a personal puzzle became The Cholesterol Code, a global research effort, a nonprofit scientific foundation, and now a forthcoming documentary film. In this episode of the LowCarbUSA Podcast, host Doug Reynolds sits down with Feldman to trace that journey—and to explain why the next chapter will take center stage at the Symposium for Metabolic Health in Boca Raton, January 23–25, 2026 The Question That Wouldn't Go Away Dave's original question was deceptively simple: Why do some metabolically healthy, lean people see their LDL cholesterol rise dramatically on a ketogenic diet? Over time, he noticed a consistent pattern. These individuals didn't just have high LDL—they also tended to have high HDL, low triglycerides, and excellent metabolic health. In 2017, he coined a name for this group: Lean Mass Hyper-Responders (LMHRs). But identifying a pattern wasn't enough. "Even if the lipid energy model proves correct," Dave explains, "does that mean having higher LDL on a ketogenic diet carries higher cardiovascular risk?" Answering that question required something far more difficult than a blog post or a hypothesis: a prospective imaging study. Building a Study When No One Will Fund One Dave spent years trying—and failing—to convince established institutions to study this population. "There's not a lot of funding to study metabolically healthy people with sky-high LDL," he says dryly. "The interest is usually in people who already have multiple cardiovascular risk factors—which confounds everything." So in 2019, he made a radical decision. He founded the Citizen Science Foundation, a public charity created for a single purpose: to fund independent research, with no money going to salaries or overhead. "We raised $200,000,"Dave says, "and paid a research center to do the study." By late 2021, recruitment was underway. One hundred lean, metabolically healthy ketogenic individuals underwent coronary CT angiography (CTA) scans to assess plaque in their coronary arteries, with follow-up scans roughly one year later. What the Data Actually Showed The early findings were striking. When Dave's cohort was matched against participants from the Miami Heart Study, there was no statistically significant difference in coronary plaque, despite Dave's group having LDL levels less than twice as high. "In fact," he notes, "our group trended toward lower plaque." But the most important finding emerged as more analyses were completed: "There was no association between ApoB or LDL and plaque progression," Dave says. "Whatever your LDL level was, it did not correspond with how plaque developed." What did matter? Baseline plaque. "Whether you're low-carb or not," he explains, "the more plaque you have at baseline, the more likely you are to see progression. That's consistent with the existing literature." When One Dataset Didn't Make Sense Then came the controversy. An AI-based quantitative analysis from a company called Cleerly showed plaque progression that appeared inconsistent—not only with Dave's other data, but with decades of prior research. "All of the scans showed progression," he says. "No regression. Not even noise." For an engineer, that raised immediate red flags. "If a bathroom scale is off by a quarter pound," Dave explains, "you expect wobble. Below the noise floor, measurements go up and down. But this dataset showed only one direction." Later, when Dave gained access to the anonymized data, he identified multiple anomalies and requested a blinded quality-control reanalysis. That request was declined. "I don't assume wrongdoing," he emphasizes. "But when something looks implausible, the response should be course correction." Instead, he sought independent confirmation. A second AI company, HeartFlow, conducted a fully blinded analysis—and its results aligned with every other analysis except Cleerly's. "Three out of four analyses agree," he says. "Cleerly is the outlier." Why This Matters Beyond One Study The implications extend far beyond a single dataset. Dave believes this episode exposes a deeper issue in nutrition and cardiovascular science: how dominant theories shape interpretation. "The lipid hypothesis has a gravitational pull," he says. "It affects what people expect to see—and what they question." As I put it, Dave has repeatedly taken the LowCarbUSA stage to announce findings that challenge assumptions—and each time, the conversation moves forward. "If we want better answers," Dave says, "we have to do better science." The Documentary—and What Comes Next All of this has reshaped his upcoming documentary, The Cholesterol Code. Originally slated for release last year, the film has been expanded to include the scientific and human story behind these findings. "We couldn't release it without covering what happened," he explains. "It's part of the truth." For the first time anywhere, the official trailer for the film will be shown at the LowCarbUSA Symposium in Boca, immediately following Dave's talk. Attendees will also be invited to help bring the film to live screenings around the world. "The world premiere of the trailer will be at your conference," Dave told me. "That alone is worth coming for." Why You'll Want to Be There One full day of the Boca symposium is dedicated to cardiovascular health, and Dave is one of the central voices shaping that conversation. Whether you attend in person or via live stream, this is a rare opportunity to engage directly with research that is still unfolding—and with the scientist who helped drive it. As Dave puts it: "The work just needs to get done, and in Boca, it will." Learn more and reserve your in-person or virtual seat for the Boca Symposium for Metabolic Health (January 23–25, 2026)
Doug Reynolds welcomes listeners back to the LowCarbUSA® Podcast with a guest who works in one of the most specialized—and most misunderstood—corners of cardiovascular medicine: the heart's electrical system. Dr. David Nabert is an electrophysiologist ("EP" doctor), focused on heart rhythm disorders, and he's one of the featured speakers at the Boca Symposium for Metabolic Health (January 23–25)—including the event's full day-plus dedicated to cardiovascular conditions. What gives this episode its pull is the combination of clinical depth and lived experience. David isn't just talking about rhythm problems from a textbook perspective—he's explaining how his own curiosity about metabolic health evolved, what shifted when he started questioning conventional assumptions, and why those questions matter for real patients in the real world. David describes how his entry point into metabolic health didn't begin in a clinic—it began with a random Google search. In 2021, while looking up a cardiology formula, he accidentally landed on a Nina Teicholz talk at the Cato Institute. "I started to watch it, and all of a sudden, an hour and a half passed," he says—one of those moments where interest turns into momentum. He listened to Teicholz's book, The Big Fat Surprise, then began searching for more voices in the low-carb space and quickly reconnected with familiar names, including Dr. Robert Cywes and Dr. Eric Westman (both will also be presenting in Boca), whom he calls mentors. That exploration ultimately led him to the Society of Metabolic Health Practitioners (The SMHP) and, importantly, a willingness to test ideas on himself. David is candid about his own weight journey. He describes a time when a body mass index under 25 felt "skinny" to him, and he's open about losing weight, regaining some after a series of hip surgeries, and continuing to work on it. What ultimately shifted, though, wasn't just the number on the scale—it was how he began to rethink what "doing everything right" actually means. For years, he approached weight loss the way many clinicians were trained to: low-fat, high willpower, endure the hunger. He describes his old strategy bluntly: "The only way I had lost weight… was by doing protein sparing modified fast… I was just eating almost no fat." Predictably, it wasn't sustainable. When he later shifted to a lower-carb, higher-fat approach—"bacon, eggs, hamburger"—he was "amazed at how quickly I started to lose weight," and he began seeing changes in markers that traditional cardiology often de-emphasizes. After stopping long-term statin therapy (which he had been on for 25 years), he saw his LDL return to roughly where it had been earlier in life, but other changes caught his attention: triglycerides dropped to the lowest he'd ever seen, HDL improved, and fasting insulin improved as well. Just as meaningful were the changes he felt: "Every 10 or 20 pounds I lost, my hips got better," he says, attributing it not only to less load, but "also part of it was less inflammation." From there, the episode moves into the heart of why David is speaking during the cardiovascular-focused programming in Boca: rhythm, electricity, and the surprising overlap between conditions that seem unrelated—like seizures and arrhythmias. David explains that early ketogenic diet research in the 1920s focused on refractory seizures, and he argues the connection matters because many antiarrhythmic drugs and antiseizure drugs overlap mechanistically. In his view, these aren't separate worlds. "Treating seizures or treating cardiac arrhythmias is basically two faces of the same coin," he says—and that opens a practical question: if ketosis can help reduce seizures, might it also influence certain rhythm symptoms? He shares a striking clinical example that stuck with him: a former submariner with PTSD and episodes of fast heart rates who said, "I know when I'm… ketogenic… when I fall off the wagon… then I start having palpitations and fast heart rates." David later learned the patient was experiencing atrial fibrillation, and while he's careful not to overpromise, he describes a pattern he's observed: in earlier stages of rhythm problems, being in a ketogenic state may reduce symptoms and potentially slow progression for some people. "It doesn't cure atrial fibrillation," he emphasizes, but he's seen ketosis "improves symptoms," not only in AFib, but in other rhythm issues like SVT and PVCs—especially early on. From there, David widens the frame to what he's seeing in younger patients—particularly young women—showing up with palpitations, rapid heart rate, anxiety, and signs of metabolic dysfunction even when they don't "look" unhealthy by BMI alone. "Only 90% of them are metabolically unhealthy," he says, describing a familiar cluster: A1C not quite normal, resting heart rates high, daytime heart rates that shouldn't be running 100–120, and a nervous system dialed up in what he calls a "hyper adrenergic state." The mainstream response is often medication—beta blockers, for example—but David argues metabolic context matters, and he's exploring how nutritional strategies (including ketosis, sometimes even supplemental ketones) may reduce symptom burden in certain cases. He also discusses POTS (Postural Orthostatic Tachycardia Syndrome), noting it can be associated with viral infections and has become more common since "the bad virus we had five years ago." Again, he's measured in his claims: ketosis isn't a cure, but he's seen it help reduce symptoms in select patients who have tried many other standard approaches first. The second half of the conversation touches on medications and the tension between "lower the number" cardiology and whole-person outcomes. David brings up PCSK9 inhibitors and recalls being troubled by early data patterns: "You were less likely to die from that, but you're more likely to die from cancer or infection… And… the overall mortality was the same." That line of thinking captures what pushed him toward metabolic health: a concern that focusing on a single marker can obscure the bigger picture of risk, resilience, and long-term outcomes. He also discusses SGLT2 inhibitors (like Jardiance and Farxiga) as potentially useful tools—especially in heart failure and diabetes—while stressing the importance of monitoring and hydration. In a moment that captures both his clinical caution and his enthusiasm for empowered patients, he tells people who go low carb on these meds to "get a Keto Mojo to check your ketone levels," because the goal is to use tools intelligently, not blindly. As the episode closes, Doug returns to the bigger mission behind the upcoming Boca program: helping attendees develop a confident, educated response to the most common fear tactic people face when they change their diet—LDL, heart attacks, and the assumption that low carb automatically means danger. Doug notes there are still "so few that really do get it and support it and talk about it," which is exactly why the cardiovascular-focused day-plus at the Boca Symposium for Metabolic Health (January 23–25) matters. David, for his part, is grateful to be part of it—and to be healthy enough to show up differently than last time. He reminds Doug that at previous events he was "either walking with one or two canes," but now, "I'm actually not going to run up on the stage, but I'll be moving pretty quickly." That moment captures the heart of the episode: metabolic health isn't theoretical. It's lived. And in Boca, that lived experience meets serious clinical discussion—especially for anyone trying to better understand cardiovascular risk, rhythm disorders, and the metabolic foundations that too often go unaddressed. If this conversation sparks your curiosity, the next step is obvious: join the community in Boca January 23–25 and immerse yourself in a day and a half of cardiovascular-focused talks designed to help you think more clearly, speak more confidently, and act more effectively—whether you're a clinician, a patient, or someone trying to help the people you love. Learn more about the Boca Symposium and register here.
Leg weakness, burning when walking, wobbling knees, or foot pain are not signs of aging. They are often early warnings of insulin resistance and metabolic dysfunction, which silently damages muscle, nerves, and circulation long before diabetes is diagnosed. Your legs are meant to be the body's largest blood sugar sponge. When insulin resistance develops, glucose cannot enter muscle cells efficiently, leading to muscle fatigue, inflammation, fat infiltration, nerve damage, and poor circulation. Common warning signs include: Heavy or tired legs while walking Burning or cramping muscles Balance issues and slower gait Difficulty standing from a chair Tingling, numbness, or cold feet Key labs that reveal the problem: Fasting insulin (optimal: 3–6) HbA1c (optimal: 5.2% or lower) Fasting glucose (70–90 mg/dL) Triglycerides under 100 HDL over 60 Triglyceride-to-HDL ratio under 1.5 The 7-step protocol to restore leg strength: Stop eating at least 3 hours before bed Strength train legs twice per week Eat 30–40g of high-quality protein per meal Lower carbs, eliminate snacking, and walk after meals Walk daily to improve circulation Support nerves with sleep, B vitamins, grounding, and red light therapy Prioritize deep, consistent sleep Ben emphasizes that leg strength is metabolic protection, not vanity, and that fixing insulin resistance can rapidly restore strength, balance, and energy.
Go to my sponsor https://trylco.com/liveleanheart and use code LiveLeanHeart to get 20% off the Comprehensive Heart Health and other select tests. Get the insights you need to live a healthier life. Heart disease is the #1 cause of death, and most people don't realize their risk is building silently for decades, even if their cholesterol test looks “normal.” In this episode of Live Lean TV, I break down why your standard cholesterol panel is missing the most important heart disease markers, and what Dr. Peter Attia actually recommends tracking for long-term cardiovascular health and longevity. According to Dr. Peter Attia, your total cholesterol number is only slightly more relevant to heart disease risk than your eye color. Instead, the real predictors are ApoB and Lp(a), two blood markers most people never test. ► Free 7 Day Trial To My Workout App: https://www.liveleantv.com ► Live Lean Body Quiz: https://www.liveleantv.com/quiz ► Free 7 Day Meal Plan And Recipes: https://www.liveleantv.com/free-stuff ⏱️ Table of Contents 00:00 Intro 00:59 Why You Need To Be Aware Of Cardiovascular Disease In Your 30's and 40's 01:32 ApoB: Your Cholesterol Test Is Missing This Heart Disease Marker 02:16 Why Lp(a) Testing Is Important For Cardiovascular Disease Risk 04:31 The Truth About Dietary Cholesterol And Heart Disease 05:53 HDL vs LDL Cholesterol Levels: What's The Difference In this video, you'll learn: ► Why heart disease risk starts building in your 30s and 40s ► What ApoB is and why it matters more than LDL cholesterol ► Why Lp(a) is a genetic risk factor you should test at least once ► The truth about dietary cholesterol, saturated fat, and heart disease ► HDL vs LDL explained in simple terms ► Why standard cholesterol tests can give a false sense of security ► The exact blood markers I personally track for heart health and longevity Subscribe Here! http://bit.ly/SubLiveLeanTV Check Out Our Top Videos! http://bit.ly/LiveLeanTVTopVideos Read the blog here: https://www.liveleantv.com/blog Listen to the podcast here: https://www.liveleantv.com/podcast WANT MORE DAILY TIPS ON HOW TO LIVE LEAN?: ► INSTAGRAM: http://www.instagram.com/bradgouthro ► INSTAGRAM: http://www.instagram.com/JessicaGouthroFitness ► INSTAGRAM: http://www.instagram.com/LiveLeanTV ► SNAPCHAT: https://www.snapchat.com/add/bradgouthro ► FACEBOOK: https://www.facebook.com/LiveLeanTV ► TWITTER: https://www.twitter.com/bradgouthro ► TWITTER: https://www.twitter.com/LiveLeanTV ► TIK-TOK: https://www.tiktok.com/@bradgouthro ► TIK-TOK: https://www.tiktok.com/@liveleantv #cholesterol #hearthealth #LiveLeanTV About Live Lean TV: Welcome to Live Lean TV. The online fitness and nutrition show, hosted by Brad and Jessica Gouthro, teaching you how to LIVE THE LEAN LIFESTYLE 365 days a year. Watch hundreds of fat blasting & muscle building workouts, easy and delicious recipes, as well as fitness and nutrition tips to get you your dream body (and maintain it 365 days a year). Make sure you click the SUBSCRIBE button for new fitness and nutrition episodes every week! Business Enquiries: info@LiveLeanTV.com Why Your Cholesterol Test Is Lying to You (ApoB, Lp(a), & Heart Disease Explained) https://youtu.be/bmALZ2tKGBA Live Lean TV https://www.youtube.com/LiveLeanTV
In this Deep Dive episode of The Trip Lab, we unpack hyperlipidemia (high cholesterol) beyond the oversimplified “LDL bad, HDL good” narrative. We also take a clear-eyed look at the most common concerns people have about statins, what the evidence actually shows, and where these medications fit—and don't fit—within a thoughtful, individualized approach to cardiovascular risk.From there, we explore integrative strategies for managing elevated cholesterol and why, for many patients, lifestyle, metabolic health, and inflammation-targeted interventions may be more effective than medications alone.In this episode, we discuss:Why cholesterol is biologically essential and not inherently pathologicalThe limitations of relying on LDL alone to assess cardiovascular riskHow inflammation, insulin resistance, genetics, hormones, and lifestyle influence lipid metabolismWhen elevated cholesterol truly signals disease—and when it may reflect a compensatory or adaptive responseThe role of advanced markers such as ApoB, Lp(a), hsCRP and CAC scoresWhy risk stratification—not fear-based medicine—should guide clinical decision-makingWhat statins can (and cannot do) and we break down the concerns people have with themWhy integrative approaches (nutrition, exercise, herbal options and mind-body medicine) truly treat the root cause of diseaseThis episode is for clinicians, patients, and anyone looking to move beyond simplistic cholesterol narratives toward a more nuanced, evidence-based understanding of cardiovascular health.
Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I'm a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients. In this episode, Dr Warrick Bishop explains the real role of cholesterol in the body and why simple labels like “good” and “bad” cholesterol don't tell the whole story. He breaks down LDL, HDL, triglycerides, and Lipoprotein(a), highlighting how each contributes to understanding cardiovascular risk.
Send us a textThere's not a lot that we both need to do and get paid to do. Dr. Michael Koren joins Kevin Geddings to discuss one of the most beneficial parts of clinical research: getting paid to do what you should be doing anyway. As an example, the doctor talks about Lp(a), a really, really, really, really bad cholesterol that increases the chances of having a heart attack and stroke. Dr. Koren explains that most people haven't had an Lp(a) test done because traditional cholesterol medications don't lower this really bad form of LDL, but that people canget an Lp(a) test done at a research center, get paid for their time and travel, and may even be referred to an Lp(a) lowering study if their numbers are high.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!
Welcome to part two of our Best of 2025 series - the moments that changed how our listeners think about their health and what they do on a day-to-day basis. In this episode, we delve into simple questions with profound impact. Is it safe to experiment with your own health? Does cheese really cause bad dreams? Why do some breakfasts leave you tired and hungry, while others don't? If you're looking for practical, science-led ideas you can take into the year ahead, this episode brings together the insights listeners found most useful, surprising, and worth returning to. Unwrap the truth about your food
Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I'm a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients. Dr. Warrick Bishop, a cardiologist and CEO of the Healthy Heart Network, discusses the importance of understanding inflammation for overall health. He explains that while acute inflammation is a beneficial response to injury, chronic low-grade inflammation is linked to serious health issues like heart disease, Alzheimer's, type 2 diabetes, and cancer. Causes of chronic inflammation include modern lifestyle factors such as highly processed foods, visceral fat (fat surrounding organs), sedentary behavior, poor sleep, stress, and environmental toxins. Gingivitis is also mentioned as a common chronic infection that can contribute to inflammation. Detecting inflammation can be done through specific blood tests like high-sensitivity C-reactive protein (HS CRP) and erythrocyte sedimentation rate (ESR), though general markers like high triglycerides, low HDL, insulin resistance, and increased waist circumference can also be indicators.
Send us a textMethods & challenges of establishing causal relationships in health research, emphasizing epidemiology, randomized trials, and genetic approaches.Topics:Epidemiology: Studies disease influences using observational designs like case-control and prospective cohorts, plus trials, to identify patterns and test hypotheses.Hierarchy of evidence critique: Rejects rigid pyramids favoring RCTs, as all studies can be biased; advocates triangulation integrating varied data types for robust conclusions.RCT strengths & weaknesses: Randomization balances confounders, but issues like poor blinding, attrition, or subversion can undermine results; large samples may yield spurious precision if biased.Confounding & reverse causation: Examples include yellow fingers and lung cancer (both from smoking) or early atherosclerosis inflating CRP-disease links; hard to fully control statistically.Nutrition epidemiology: Observational studies often overstate benefits (e.g., vitamin E for heart disease), leading to failed trials; incentives favor new findings over revisiting errors.Mendelian randomization: Uses genetic variants as proxies for exposures (e.g., ALDH2 for alcohol metabolism) to mimic randomization; reveals no heart benefits from alcohol, unlike observational data.Negative controls: Tests implausible outcomes (e.g., smoking and murder) or exposures (e.g., paternal smoking in pregnancy) to check for confounding artifacts.Evidence triangulation: Combines diverse studies with different biases (e.g., cross-cultural comparisons) for causality; applied to dismiss HDL-raising drugs despite initial promise.Practical Takeaways:Scrutinize health claims by checking for negative controls or variety in evidence sources to avoid mistaking correlation for causation.For personal decisions like alcohol intake, consider genetic studies showing risks at all levels, and aim for moderation or abstinence based on overall evidence.When evaluating supplements or diets, prioritize trials over observational data, and question media hype that ignores confounding factors.About the guest: Dr. George Davey Smith, MD, DSc is a professor of clinical epidemiology at the University of Bristol and director of the MRC Integrative Epidemiology Unit.*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts
Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I'm a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients. Dr. Warrick Bishop, a cardiologist and author, discusses reversing metabolic syndrome, which he also calls the "modern syndrome." He explains that metabolic syndrome is not a disease itself but a warning sign of increased risk for heart disease, stroke, type 2 diabetes, kidney disease, and dementia. The syndrome is characterized by having at least three of five criteria: elevated waist circumference, high triglycerides, low HDL cholesterol, high blood pressure, and elevated fasting blood sugar. The root cause is often insulin resistance, where the body's cells stop responding properly to insulin, a hormone responsible for energy storage. This resistance is exacerbated by modern diets high in carbohydrates and a sedentary lifestyle. Other contributing factors include sleep deprivation, chronic stress, and genetic predisposition.
In this episode, Ben Azadi breaks down five science-backed metabolic drinks that naturally reduce arterial plaque, boost nitric oxide, lower inflammation, and support metabolic health — without medications or side effects. You'll learn: • Why arterial inflammation — not cholesterol — is the real silent killer• How pomegranate juice reversed arterial plaque by 30% in human studies• The surprising cardiovascular benefits of high-quality coffee with butter, olive oil, and salt• Why raw cacao improves arterial flexibility by up to 400% (Harvard study)• How apple cider vinegar and cinnamon lower fasting glucose, HbA1c, and triglycerides• The anti-inflammatory power of turmeric + black pepper and how it calms the arteries Ben also explains:• Which drink is best for diabetics• How to rotate the drinks weekly for maximum benefit• What markers to test before and after 30 days to measure progress (ApoB, CRP, fasting insulin, triglycerides, HDL, CAC score, and more) Plus, he shares a free guide revealing the five vegetables silently inflaming your gut and slowing your metabolism — and what to eat instead. A simple daily cup could dramatically upgrade your cardiovascular and metabolic health. FREE GUIDE: 5 Vegetables You Must Avoid To Lose Weight & Belly Fat - https://bit.ly/48CIprn
In this episode, Mel and Kara break down the simple, real-food strategies that help you enjoy the season without the blood sugar crashes, cravings, or cardiometabolic backslide. Learn how holiday habits impact triglycerides, HDL, and insulin sensitivity--and how small changes (like eating before an event, building balanced meals, and the 50% movement rule) can keep you energized, steady, and feeling your best. If you want to stay healthy without missing out on the fun, this episode gives you a practical plan you can actually follow.
California became the first state in the U.S. to ban ultraprocessed foods from public school lunches under the "Real Food, Healthy Kids Act," but the full phase-out won't take effect until 2035 Ultraprocessed foods — packed with vegetable oils, additives, and refined sugars — are engineered to trigger cravings and disrupt metabolism, contributing to childhood obesity, insulin resistance, and fatty liver disease A study in JAMA Network Open found that preschoolers who ate the most ultraprocessed foods had higher body fat, larger waistlines, elevated blood sugar, and lower levels of protective HDL cholesterol The delayed timeline leaves millions of children unprotected for nearly a decade, underscoring the urgent need for parents to remove ultraprocessed foods and vegetable oils from their homes now You can protect your child's long-term health by replacing processed snacks with real foods, eliminating vegetable oils, cooking at home, reducing exposure to junk food ads, and teaching kids how to spot marketing tricks
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor field your most urgent metabolic health questions—exploring care advocacy, novel drug use, lab results, and how to filter fact from fiction in the TikTok age. Dr. Cooper offers clinical clarity, real-world perspective, and actionable hope—with an emphasis on what truly matters for your long-term health and energy.Hear from listeners experiencing real breakthroughs (and challenges) with GLP-1s, get tips for navigating confusing cholesterol results, and learn why self-advocacy and good science matter more than credentials or hype. This is not a quick-fix episode; it's real metabolic medicine, mythbusting, and grounded encouragement for your health journey.Key Questions AnsweredWhat labs and scores best assess your true metabolic risk—and how do you make sense of fasting glucose, glucose-insulin ratio (GIR), and FIB-4?How can you find a medical provider who'll actually give you the time and attention metabolic care requires?Why do GLP-1s benefit more than weight loss alone? Listeners report help with sleep apnea, inflammation, and food noise—what does the science say?How should you reintroduce carbs after restriction, and what's the safest way to monitor (beyond A1C)?What's up with rising cholesterol on Zepbound, and when do you worry?Does serotonin syndrome relate to GLP-1s? (Short answer: No—Dr. Cooper explains why.)What are the dangers of “GLP-1 microdosing” as pushed by social media, and what happens when influencers overstep good science?Key TakeawaysCare that cares: The best doctor isn't always the most credentialed—find someone, MD, NP, or PA, who takes your questions seriously and goes deeper than the surface. Labs that matter: Fasting glucose, insulin, GIR, HbA1c, plus advanced lipid testing (CardioIQ, NMR) are critical for uncovering hidden risk—not just chasing numbers. GLP-1s act broadly: Listeners see gains in sleep, inflammation, and appetite regulation. These benefits are real, not just anecdotal, and Dr. Cooper shares the clinical rationale. Smart fueling, even on GLP-1s: If you lack hunger cues, “mechanical eating” prevents under-fueling and cellular stress—especially important for maintaining muscle and metabolism. Rethinking “microdosing”: TikTok trends are not medical advice—microdosing with black-market GLP-1s is unproven, poorly regulated, and potentially unsafe. Rely on trusted, legal medication sources only. Dr. Cooper's Actionable TipsRequest a full panel for metabolic health: ask your provider about fasting insulin, GIR, HbA1c, lipids, and FIB-4—even if you haven't been flagged as “at risk”. For those on GLP-1s: Don't skip meals; create a schedule with protein and fiber to avoid muscle loss and ensure micronutrient intake. Experiencing cholesterol shifts on medication? Ask for a breakdown (HDL, LDL, particle size) and consider advanced panels (CardioIQ, NMR) to better understand your risk. If reintroducing carbs after restriction, pair them with protein or fat and test glucose/insulin at intervals post-meal to personalize your plan. Avoid unregulated “microdosing” and buy only from reputable, FDA-approved outlets—protect your long-term health over quick fixes. Notable Quote“The most important thing is somebody who cares, not necessarily their degrees.”— Dr. Emily CooperLinks & ResourcesPodcast Home: Fat Science Podcast WebsiteSubmit a Show Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.comDr. Emily Cooper on LinkedInMark Wright on LinkedInAndrea Taylor on InstagramAdvanced cholesterol testing: CardioIQ at Quest, NMR at LabCorpFat Science is your source for breaking diet myths and advancing the science of true metabolic health. No diets, no agendas—just science that makes you feel better. The show is informational only and does not constitute medical advice.
Why have we lost our trust in natural medicine? In this video, we'll discuss why natural medicine is ignored and sometimes even dismissed as folklore. Is it wise to invalidate the wisdom of the past? Discover the truth about natural medicine in this video.0:00 Introduction: Natural medicine suppression0:19 United States Dispensatory 0:38 Pharmaceutical vs. natural medicine 3:08 The advancement of medicine 6:35 Natural remedies of the past The “United States Dispensatory” by Wood and Lawall may provide insight into alternative medicine censorship in the United States. The 21st edition, published in 1926, was the most authoritative and comprehensive reference for American medicine. At the time of publication, 75% of medicine consisted of various natural remedies, while only 25% consisted of synthetic compounds.Since then, there's been a gradual transition from natural remedies to synthetic drugs. When the 22nd edition of the book was published in 1943, the ratio of natural to synthetic drugs shifted to 50:50.Today, medicine is often prescribed without considering lifestyle, eating habits, sleep patterns, stress levels, or the microbiome. Symptoms of the underlying problems are treated without addressing the root cause.Discover these 20 natural remedies that have stood the test of time, along with the ailment they have historically been used to address.1. Cod liver oil—Tuberculosis, tetany, nerve pain2. Nutmeg oil—Psychotic problems3. Olive oil—Mild laxative, gallstones 4. Pine needle oil—Eliminates mucus from the lungs 5. Castor oil—Mild laxative 6. Sandalwood oil—Gonorrhea, bronchitis, bladder infections 7. Sassafras oil—Antiseptic 8. Betaine hydrochloride—Indigestion, gastric problems9. Pepsin—Digestive issues 10. Lugol's iodine—Thyroid support and protection 11. Magnesium sulfate—Sleep support, anxiety, pain killer 12. Calcium chloride—Acidifies the body 13. Liver extract—Anemia 14. Methylene blue—Shrinks tumors, meningitis, bladder infections, gonorrhea, and supports the mitochondria15. Lithium carbonate—Relaxation, anxiety, and depression relief16. Glauber's salt—Laxative17. Vitamin D—Autoimmune conditions18. Colloidal silver19. Activated charcoal—Food poisoning, gas20. Niacin—Lowers triglycerides, increases HDL, increases lifespan, supports cardiovascular health, acts as a NAD precursorDr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the Director of Dr. Berg Nutritionals and author of the best-selling book The Healthy Keto Plan. He no longer practices, but focuses on health education through social media.Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.
High-intensity interval training (HIIT) improves health without weight loss. Research shows that short high-intensity workouts boost cardiovascular health, and reduce body fat HIIT also increased HDL cholesterol levels, lowered blood pressure, and improved peak oxygen consumption (VO2peak) in overweight teens Prediabetics also benefit from HIIT. Analysis shows it outperformed continuous aerobic training by improving insulin sensitivity, glucose processing, and creating more energy-producing mitochondria Moderation is key for safety. An expert recommends limiting high-intensity exercise to 75 minutes weekly and strength training to 40 to 60 minutes weekly to avoid diminishing returns and health risks Effective sessions include a three-minute warmup, six minutes of high-intensity cardio, and combining cardio with strength training twice weekly
Heart disease is still our number one killer, even though 50 million Americans have been prescribed a cholesterol-lowering statin. Cardiologists pay a lot of attention to cholesterol in all its variety: total cholesterol, LDL, HDL, VLDL. Even blood fats like triglycerides and lipoprotein a [Lp(a)] are getting some attention. What else do you need to […]
Episode 2708 - Vinnie Tortorich and Chris Shaffer welcome call-in guests to discuss motivation sparked by one foot in the grave, and pushback from family. https://vinnietortorich.com/2025/10/one-foot-in-the-grave-episode-2708 PLEASE SUPPORT OUR SPONSORS YOU CAN WATCH THIS EPISODE ON YOUTUBE - One Foot In The Grave Social media concerns. (2:00) Vinnie had an experience over X years ago regarding American Girl dolls. (4:00) There was a miscommunication, and he had to stay up all night to correct the mistake. Vinnie had only suggested making a fitness-themed doll. Eric is the first guest caller. (18:00) He's lost some weight with NSNG® and has spine issues. Eric is looking forward to Vinnie's workout videos that will be released in the NSNG® VIP group. They discuss issues Eric has had dealing with cholesterol and his doctor. (30:00) The ratio between HDL and Triglycerides is a better indicator of heart health. Carbohydrates really don't help you build muscle; 5g of creatine is better. (43:00) Some sports or competitions can be fueled with a small sugar trickle because blood glycogen gets used up so quickly. Examples would be kickboxing or boxing. Family Pushback Scott is the next guest. He has lost 325 pounds after starting NSNG® after hearing Vinnie on Mike Rowe's podcast. Why does it take people to be told they have one foot in the grave before it sparks change? (48:00) Scott's wife has lost over 100 pounds, and his son has lost 90 pounds! Scott has reversed COPD and congestive heart failure symptoms. (55:00) Hobbies are important to help your mind explore. (1:01:00) Scott has had family blowback about his new healthy lifestyle. A family member reported him to Adult Protective Services! (1:04:00) He had to go through three months of investigation. The accusation was abuse because of the change in eating and daily walks. Scott's wife has lowered her A1C and gotten off of insulin. (1:11:00) Vinnie shares a story about an NSNG® follower named Robert Stanton. (1:19:00) If you are interested in the NSNG® VIP group, it will be reopening soon. But you can get on the wait list - More News If you are interested in the NSNG® VIP group, it will be reopening soon. But you can get on the wait list - Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. “Dirty Keto” is available on Amazon! You can purchase or rent it . Make sure you watch, rate, and review it! Eat Happy Italian, Anna's next cookbook, is available! You can go to You can order it from . Anna's recipes are in her cookbooks, website, and Substack–they will spice up your day! Don't forget you can invest in Anna's Eat Happy Kitchen through StartEngine. Details are at Eat Happy Kitchen. PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: