Podcasts about Statin

The impact of tariffs on the prices of nutraceuticalsSwitching from seed oils to tallow in restaurants is great, but is the tallow from grass-fed beef?My LDL is high after stopping my statin and starting intermittent fasting

Q-BANK: https://patreon.com/highyieldfamilymedicineIntro 0:35,Dyslipidemias 1:48,Statins 4:24,Statin side effects 6:22,Non-statin lipid lowering medications 8:17,Familial Hypercholesterolemia 11:45,Obesity 12:52,Weight loss medications 15:25,Bariatric surgery 19:04,Practice questions 22:19,

Interview with Alexander C. Fanaroff, MD, MHS, author of Encouraging Pharmacist Referrals for Evidence-Based Statin Initiation: Two Cluster Randomized Clinical Trials. Hosted by Ann Marie Navar, MD, PhD. Related Content: Encouraging Pharmacist Referrals for Evidence-Based Statin Initiation

Interview with Alexander C. Fanaroff, MD, MHS, author of Encouraging Pharmacist Referrals for Evidence-Based Statin Initiation: Two Cluster Randomized Clinical Trials. Hosted by Ann Marie Navar, MD, PhD. Related Content: Encouraging Pharmacist Referrals for Evidence-Based Statin Initiation

**Dr. Lisa Faast discusses the prescription vitamin Xyzbac, a powerful supplement for statin patients. Xyzbac contains CoQ10, a vital nutrient often depleted by statin use.** **Show Notes:** 1. **importance of pharmacists recommending Xyzbac** [0:0] Websites Mentioned: https://www.drlisafaast.com/ ----- #### **Becoming a Badass Pharmacy Owner Podcast is a Proud to be Apart of the Pharmacy Podcast Network**

ไลฟ์ #88: กินยาลดไขมันกลุ่ม statin ยืดอายุการตายได้นานกว่าแค่ 3 วัน เมื่อเทียบกับกลุ่มที่ไม่ได้รับยา…จริงหรือ?วันจันทร์ 30 ธ.ค. 2567เวลา 20.00 น.เพิ่งชม vdo ล่าสุด “Do Statins only add 3 DAYS to your life?!” ทางช่องวิทยาศาสตร์สุขภาพโปรดของพี่ Nutrition Made Simple โดย Dr.Gil Carvalho ซึ่งอธิบายได้ถ่องแท้มาก จนพี่ตัดสินใจเลือกนำมาสรุปเป็นไลฟ์ส่งท้ายปี 2567 ให้น้องๆฟังกันว่าประโยคดังกล่าว…จริงหรือ?พี่เห็น Health Influencers จำนวนหนึ่ง ทั้งในไทยและต่างประเทศ ที่สำคัญเป็นบุคคลากรทางการแพทย์เสียด้วย ซึ่งปฏิเสธการได้รับยากลุ่ม Statins เพื่อลดระดับคอเลสเตอรอลในเลือด โดยอ้างอิงงานวิจัยฉบับหนึ่งซึ่งให้ข้อสรุปว่า กลุ่มคนที่ได้รับยากลุ่ม statins vs กลุ่มที่ไม่ได้รับยา แล้วติดตามไป 5 ปี พบว่ากลุ่มที่ได้รับยา statins ตายช้ากว่ากลุ่มที่ไม่ได้รับยาแค่ 3 วัน แล้วก็สาธยายอาการข้างเคียงของยากลุ่ม statins ซะจนน่ากลัว เช่น ทำให้สมองเสื่อม ทำลายตับ ลดการผลิตฮอร์โมนเพศ ฯลฯแล้วก็นำงานวิจัยนี้มาชวนเชื่อสาวกให้ปฏิเสธการได้รับยากลุ่ม statins จากแพทย์ ทำให้เป็นเรื่องขบขันในกลุ่มสาวกว่ากินยาไปตลอดชีวิตกลับตายช้ากว่าแค่ 3 วัน โดยไม่ได้อ่านสิ่งที่ผู้ทำงานวิจัยฉบับนี้เขียนข้อสรุปในการแปลผลทางสถิติของงานวิจัยว่ามีข้อจำกัดอะไรบ้าง พี่จึงเห็นว่าไลฟ์นี้จะช่วยให้ข้อเท็จจริงที่ health influencers กลุ่มนี้ไม่เข้าใจ จะทำให้เราไม่ตกเป็นเหยื่อ health influencers ที่ไม่ได้มีความเข้าใจสถิติเบื้องต้น ไม่เข้าใจระเบียบวิธีวิจัย และการแปลผลข้อมูลทางสถิติ ที่สำคัญไม่อ่านงานวิจัยให้ละเอียดถี่ถ้วน แต่มีทักษะในการ “เล่าเรื่อง” ชวนเชื่อได้เคลิ้มมาก

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In 2015, I discovered my cholesterol levels were rising, my APOB was high-risk, and I was prediabetic. I also carried the APOE4 allele, a risk factor for Alzheimer's, and was a hyper-absorber of cholesterol. By 2020, post-menopause, my numbers had doubled, and in 2022, I learned I was also a hyposynthesizer, meaning my body now overproduced cholesterol. Despite a lifelong healthy lifestyle, I faced an uphill battle.If this sounds confusing, stay with me—today's episode is about screening and solutions for preventing heart disease during menopause and beyond - still the #1 killer of women. The internet is full of conflicting and fear-mongering guidance when it comes to women's heart disease risk and prevention. This episode will gift you with the current science on:-Women's Health Initiative findings on heart disease and hormone therapy-Estrogen's protective effects on the heart and whole body-What lab biomarkers are essential to assessing risk-What is the Cholesterol Balance Test?-Statin therapy options-Should you get a CAC Scan (coronary calcium score)My special guest, Dr. Thomas Dayspring, is a leading expert in lipidology and women's cardiovascular health. A renowned educator and clinician, he has given over 4,000 lectures, authored lipid textbook chapters, and is a trusted voice in cardiovascular medicine. His expertise will help midlife women navigate heart disease risk with science-backed insights and practical solutions.Medical Disclaimer:By listening to this podcast, you agree not to use this podcast as medical advice or to make any lifestyle changes to treat any medical condition in yourself or others. Consult your own physician for any medical issues that you may be having. This entire disclaimer also applies to any of my guests on my podcast.To follow Dr. Dayspring:X: @drlipid LinkedIn: https://www.linkedin.com/in/thomas-dayspring-md-facp-fnla-3aaa876/Stay connected to JFW:Watch on my YouTube channel: https://www.youtube.com/@jillfooswellness/videosFollow me on Instagram: https://www.instagram.com/jillfooswellness/Follow me on Facebook: https://www.facebook.com/jillfooswellnessGrab discounts on my favorite biohacking products: https://www.jillfooswellness.com/health-productsEnjoy 20% savings and free shipping at Fullscript for your favorite supplements by leading brands:https://us.fullscript.com/welcome/jillfooswellnessSubscribe to the JFW newsletter at www.jillfooswellness.com and receive your FREE Guide on How To Increase Your Protein in 5 Easy Steps and your free Protein Powder Recipe Ebook. Schedule your complimentary 30-minute Zoom consultation here:https://calendly.com/jillfooswellness/30-minute-zoom-consultations

Case Discussion 119: CAC Score

My husband's doctor is recommending a statin even though his lipid panel is great.  What say you?Anti-vaccine doctor wins bid to resume medical practice in Australia.Do I need to take vitamin D3 and K2 together? Can I take them at different times of day?My liver function tests are normal but my SMA test remains high.  What do I make of this?

Today's show is brought to you by MYOXCIENCE.  In this episode, heart surgeon and best selling author Dr. Phil Ovadia discusses the foods and lifestyle factors driving a new wave of early-onset heart disease. Sponsored by MYOXCIENCE: Support your Intermittent Fasting lifestyle with the Berberine Fasting Accelerator by MYOXCIENCE: https://bit.ly/berberine-fasting-accelerator Use code podcast to save 12% Link to full show notes and articles: https://bit.ly/3uKRKMC Connect with Dr. Ovadia: https://ifixhearts.com/quiz/ Show Notes: 0:00 Intro 1:30 Up to 95% of people with cardiac disease are insulin resistant. 4:45 Processed foods and high carbs are the two primary drivers of metabolic disease, the primary driver of heart disease. 6:53 Insulin resistance damages blood vessels. 11:18 Exercise is indirectly helpful in preventing atherosclerosis. 13:10 The better you can maintain muscle as you age, the better you can deal with the aging process. 14:30 It is possible to reverse atherosclerosis. 16:30 Tests: coronary artery calcium scan (CAC) and coronary CT angiogram (CCTA). 18:30 People in their 30s and 40s now end up on the cardiac operating table. 20:30 High LDL may not be dangerous in a person who is metabolically healthy. 21:00 The quality of your LDL particles is important. 22:54 90% of adults are metabolically unhealthy, so their high LDL is likely dangerous. 24:05 Statin use for over 10 years increases your risk of developing insulin resistance and type 2 diabetes, primary drivers of heart disease. 26:30 Inflammation is an important part of the development of heart disease. 27:40 High blood pressure root cause is insulin resistance/metabolic disease. 31:41 Ferritin testing measures total body iron stores. It is also an inflammation marker. 35:50 Linoleic acid LDL oxidation hypothesis 37:30 Plant-based diets 40:25 Lowering your intake of omega 6 improves your omega 3 index. 41:10 Low vitamin D 42:00 Sun exposure has been misunderstood. 44:10 Triglycerides is a higher risk than LDL. 48:30 Bioidentical hormones are superior to synthetic. 50:03 Low testosterone is a risk factor for heart disease. 53:10 Heart surgery does not fix the underlying problem.      

Damon Alvarez, PharmD, MBA provides insights on statin use in people living with HIV.   For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.  You can also connect with the Mayo Clinic's School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE 

Pooling data from the PROMINENT, REDUCE-IT, and STRENGTH trials, Paul Ridker and C. Michael Gibson discuss the residual inflammatory risks for patients treated with statins.

Dr. Bob Martin answers callers' health questions: are there blood tests capable of detecting cancer? Should you get rid of your Smartphone because it emits dangerous EMF's? What to do for a young that doesn't seem to be growing at a healthy rate? If your hands are numb, do you have neuropathy and is Gabapentin a good treatment? After being on two Statin / cholesterol lowering drugs for 30 years – a callers' doctor want to start him on an injectable drugs, Repatha, is that a good idea? How to help reduce nighttime bathroom trips? Is it ok to snack on mini marshmallows? How to help hand tremors without using drugs?Health Alternative of the WeekProduct Recall of the WeekHealth Mystery of the Week

Highlight presentations from ACR 2024 in Washington, DC Covered abstracts include: - Dr. Kavanaugh 1679 Amplified & biomarkers 0082 Enthesitis Pathology & IL-23 1553 TLR 7/8 inhibitors in SLE 995 Carbon footprint to injectables L20 ARTHUR DIANA Automated US 1132 VEGA (Combo Rx – see also 2640, 1460, 1393) 1745 Statin use in Oral Surveillance - Dr. Cush 458 Seronegative RA fate L19 Emapalumab in Stills disease ACR 2024 updated guidelines on lupus nephritis 2580 Ianalumab in SLE 2259 Anti-Obesity Meds in RA 2657 Mortality with starting/stopping steroids 0774  TAPIR study in GCA 1697  PMR MODE study

Thank you for tuning in for another episode of Life's Best Medicine. Dr. Paul Mason is a Fellowship trained Sports and Exercise Medicine Physician with degrees in Medicine, Physiotherapy, and Occupational Health. He has significant expertise in medical nutrition therapy, especially with respect to low-carb, ketogenic, paleolithic, and carnivore diets. In this conversation, Drs. Brian and Paul talk about… (04:34) Why it is important for you to do your own research and be your own health advocate (06:38) Lectins and plant foods (10:05) The medical system in Australia and financial conflicts of interest in the medical/pharmaceutical fields (25:14) How to fix glaring flaws in the medical system (33:29) Statin drugs and lack of transparency from drug companies (42:08) How patient care can be made more effective than the conventional model (45:58) Why diabetes is increasing and how pesticides are involved (54:07) Nutrient deficiency in the soil and the downstream effects of this phenomenon For more information, please see the links below. Thank you for listening! Thank you for listening. Have a blessed day and stay healthy!   Links:   Dr. Paul Mason: Website YouTube X   Dr. Brian Lenzkes:  Arizona Metabolic Health Low Carb MD Podcast   HLTH Code: HLTH Code Promo Code: METHEALTH HLTH Code Website   Keto Mojo: • • Keto Mojo

Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I'm a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients. In this episode, Warrick Bishop discusses the use of statin therapy in relation to chemotherapy, specifically its potential to reduce heart failure progression in patients receiving anthracycline treatments for lymphoma. He highlights the STOP CA trial, which aimed to assess the effectiveness of atorvastatin in preventing cardiac dysfunction associated with these cardiotoxic medications. The study involved a double-blind, placebo-controlled design and included patients aged 18 and older who were scheduled for anthracycline therapy. Exclusion criteria ensured a clear focus on participants without prior statin therapy or certain health conditions.

This is a replay of one of the most-downloaded episodes of AGE BETTER in 2024.     Take a deep dive into the heart of midlife cardiovascular wellness with this important episode of "Age Better," where host Barbara Hannah Grufferman talks with Dr. Melissa Tracy, a top-tier cardiologist from the RUSH University Medical Center. Dr. Tracy is also the Medical Director of the Cardiac Rehabilitation Program at RUSH.     Dr. Tracy gives a masterclass on statins - those powerhouse medications at the forefront of cholesterol management and heart disease prevention. But the question that lies at the core of this discussion is one that resonates with millions: Who really needs to be on statins? By tuning in, you'll get the knowledge and tools you need to make the decision that is right for you.     KEY TAKEAWAYS:  Understanding Statins: Learn how these powerful medications aid in reducing cholesterol and preventing cardiovascular disease.    Postmenopause and Heart Health: Discover the unique impact of statins for women in midlife.    Shared Decision-Making: The importance of patient-doctor collaboration in deciding if statins are right for you.    Coronary Calcium Score: Uncover how this test is crucial in assessing cardiovascular risks.    Side Effects & Alternatives: Insights into common side effects of statins and who should avoid them, plus a look at natural supplements and other cholesterol management strategies.    Personalized Healthcare: Dr. Tracy emphasizes individualized treatment plans and the role of lifestyle changes alongside statins.    Future-Focused Discussion: A sneak peek into ongoing assessments and evolving conversations in heart health management.    KEY LINKS:  Learn More About Dr. Melissa Tracy: https://doctors.rush.edu/details/1183  What is Cardiac Rehabilitation? https://www.kevinmd.com/2024/02/a-people-first-approach-to-cardiac-rehabilitation.html  USNews+WorldReport Article: https://www.usnews.com/news/health-news/articles/2024-03-05/statin-meds-cholesterol-what-you-need-to-know  Alternatives to Statins Referenced During the Episode:   Ezetimibe: https://www.mayoclinic.org/drugs-supplements/ezetimibe-oral-route/description/drg-20067172  Bempedoic Acid: https://www.mayoclinic.org/drugs-supplements/bempedoic-acid-oral-route/side-effects/drg-20484223?p=1  PCSK9 inhibitors: https://www.medicalnewstoday.com/articles/pcsk9-inhibitor#definition    Whether you're on a statin already, or giving it serious consideration … this episode will help you make the decision that is right for you.    Listen and Subscribe   Remember to subscribe or follow the "Age Better with Barbara Hannah Grufferman" podcast on platforms like Apple Podcasts, Spotify, and YouTube. Yep, you can watch it or just listen!     Share Your Ideas and Questions   Your questions have spurred many episodes, so please keep them coming! Share your ideas for topics and guest suggestions at agebetterpodcast@gmail.com  Learn more about your ad choices. Visit megaphone.fm/adchoices

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs: https://membership.metabolicinitiative.comIn this episode, we're sharing a presentation from Metabolic Health Summit 2024 that dives into a groundbreaking experiment titled "Oreo vs. Statin," by researcher-educator Nick Norwitz, PhD. What started as a personal journey with metabolic health turned into a captivating exploration of the lipid energy model and lean mass hyper responders. Dr. Norwitz shares the dramatic results of his unorthodox study, where a diet consisting primarily of Oreos led to a jaw-dropping 70% reduction in LDL cholesterol. We discuss the implications of his findings, the challenges he's faced in the scientific community, and the importance of asking uncomfortable questions in pursuit of knowledge. This episode is an opportunity to watch an engaging lecture filled with scientific awe, unexpected results, and a call to action for more open-minded discussions in metabolic health!Dr. Nick Norwitz has a mission to “Make Metabolic Health Mainstream.” He graduated Valedictorian from Dartmouth College in 2018, majoring in Cell Biology and Biochemistry. He then completed his PhD in Metabolism at the University of Oxford in 2021, before attending Harvard Medical School to complete his MD. Dr. Norwitz enthusiasm for the field of Metabolism derives from a personal struggle with severe Inflammatory Bowel Disease that left him physically emaciated, mentally depleted, and emotionally fragmented. In desperation, he found that a ketogenic diet put his disease into remission where conventional approaches had failed.Special thanks to the sponsor of this episode: Genova Connect, powered by Genova Diagnostics offers easy access to advanced lab tests. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclinkLearn more about Dr. Norwitz here: https://www.nicknorwitz.comIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on impact of guideline-directed statin prescriptions on cardiovascular outcomes by race in a real-world primary prevention cohort.

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Dr. Prather has a high success rate in treating Peripheral Neuropathy, which he says is "unusual".  In this episode, find out:—How Diabetes is the most common reason for Peripheral Neuropathy, where a Diabetic has a 50% chance of having Neuropathy.  And how it is "rare" to go through Chemotherapy without experiencing Neuropathy as a side-effect.—The connection between Neuropathy and Free Radical Pathology.  And how getting Free Radicals under control is also a key to slowing down the aging process and preventing diseases such as Cardiovascular Disease and Cancer.—Why Dr. Prather says he believes one of the reasons for his success in treating Peripheral Neuropathy is because his office addresses the viruses (like the  Coxsackie B virus) affecting the nervous system. —How prescription drugs, especially Statin drugs, can be a major contributor to Neuropathy.  And how even some of the nerve drugs prescribed for Neuropathy can actually CAUSE Neuropathy. —The Diathermy treatment that Dr. Prather says is "like a magic formula" for Neuropathy and a key reason for his success rate in treating the condition.—The stories of how Dr. Prather has helped many Neuropathy patients to avoid amputations.—How the Chinese liniments used at Holistic Integration can often provide immediate pain relief for Neuropathy.  And the reason Dr. Prather does not use the Capsacin liniments more commonly used for Neuropathy.—Why Chiropractic and Acupuncture are helpful for treating Neuropathy.  And the lifestyle changes recommended for Neuropathy patients, including smoking cessation, exercise, and proper nutritional support through diet.—The necessary diagnostics for Neuropathy.  And how Dr. Prather is able to even detect Neuropathy early before the patients are even complaining about their symptoms.—Plus, we reveal the details about how you can be a part of our FREE Holistic Heart Open House event with Dr. Prather on Wednesday, October 23, 2024 at 6 p.m.http://www.TheVoiceOfHealthRadio.com

Reason for Visit: The patient is a 76-year-old Hispanic referred to the ambulatory care pharmacist for dyslipidemia management.  The patient has a remote history of an MI (15 years ago) but states he is unable to take statins. Guest Authors: Mayela Warner, PharmD and Maricar Conson, PharmD, BCPS Expert Panelists: Sara Wettergreen, PharmD, BCACP, BC-ADM and Tomasz Jurga, PharmD, BCPS, BCACP, BCCP, CDCES Music by Good Talk

Cholesterol has gotten a bad rap! By now I'm sure you've heard how bad cholesterol is for your heart and body, but this simply isn't true. In this episode, I talk about why cholesterol isn't the villain conventional medicine has made it out to be. You're about to learn why cholesterol is critical to your health!In this episode you'll discover:Why the “normal” cholesterol range isn't accurateThe lies we've been told about cholesterol's role in heart attacksCholesterol's real functions within the body  Why you need cholesterol to make certain hormonesWhere most of your cholesterol comes from (it's not what you think!)The link between cholesterol and menopause And much more!After listening to this episode, you'll understand why cholesterol is your friend and is important for your health. Stop being afraid of cholesterol and enjoy foods with cholesterol, guilt-free! Struggling with Hormonal Imbalance & Belly Fat? Discover your Personalized Solution! Are You Ready To Feel Good In Your Clothes Again? Start your journey with a new App "Fast to Faith." Support your hormone balance with Hormone Tame Essentials Multivitamin. Connect with Dr. Tabatha and the Team at Her Higher Health: Schedule Free a Zoom CallDr. Tabatha's Facebook: https://www.facebook.com/DrTabathaDr. Tabatha's IG: https://www.instagram.com/gutsydrtabatha/Dr. Tabatha's YouTube: https://www.youtube.com/@fasttofaith

In this episode, explore the fascinating world of cholesterol dynamics with Dr. Nick Norwitz as he challenges conventional wisdom. Discover the significance of understanding cholesterol risk profiles, particularly in lean mass hyper-responders on a ketogenic diet.   Dive into Dr. Norwitz's bold “Oreo vs. Statin” study, which uncovers surprising insights about cholesterol management. Learn how this experiment highlights the need to reassess traditional approaches to heart health.   Gain valuable knowledge on why LDL cholesterol should not be the sole focus when evaluating cardiovascular risk. Understand the importance of a holistic view that considers individual metabolic health. In This Episode:   00:00 Understanding LDL and Cardiovascular Risk 04:08 Episode Overview: Oreo Cookie Study 07:24 Interview with Dr. Nicholas Norowitz 08:20 The Oreo Cookie Experiment 15:59 Exploring the Lean Mass Hyper Responder Phenomenon 34:43 Understanding VLDL and Triglyceride Metabolism 35:28 The Triad: LDL, HDL, and Triglycerides 36:36 Exploring the Lipid Energy Model 37:30 Insulin's Role in Fat Metabolism 38:22 Clinical Data and Metabolic Profiles 41:20 The Controversy of LDL Particles 46:26 The Lean Mass Hyper Responder Phenotype 52:49 Personal Journey with Ketogenic Diet 58:01 Side Effects of Statin Drugs 01:02:20 Satiety Per Calorie and Marketing Tactics 01:07:47 Conclusion and Final Thoughts   This episode is sponsored by Paleo Valley and their Organic Supergreens powder, a product I love for its high chlorophyll content, which supports blood purification, detoxification, and mitochondrial health. Packed with digestive-supportive superfoods like ginger, lemon, and beet, it's free from cereal grasses, making it gentle on the gut, especially for those with chronic inflammation.   I mix a scoop in water daily, usually after lunch, for an energy boost and mental clarity. You can save 15% on any Paleo Valley product, including their Organic Supergreens, by visiting paleovalley.com/jockers     This podcast is sponsored by ShopC60.com. C60 is a powerful, Nobel Prize-winning antioxidant that helps to optimize mitochondrial function, fights inflammation, and neutralizes toxic free radicals! I'm a big fan of using C60 in conjunction with your keto and intermittent fasting lifestyle to support your immune system, help your body detox, and increase energy and mental clarity. My favorite C60 products for Keto & IF lifestyles include C60 Purple Power in Organic MCT Coconut Oil (you can add this to your coffee) and their delicious Sugar-Free C60 Gummies (made with allulose and monk fruit)! If you are over the age of 40, and you'd like to kick fatigue and brain fog to the curb this year, visit shopc60.com and use the coupon code “JOCKERS” for 15% OFF  and start taking back control over your health today!     “The physiology behind lean mass hyper-responders is an incredible natural experiment, a gift to science.” -Dr. Nick Norwitz   Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio     Resources: Visit https://shopc60.com/jockers – Use code “JOCKERS” to get 15% off! Paleovalley's Supergreens - visit paleovalley.com/jockers Oreo Study - https://pubmed.ncbi.nlm.nih.gov/38276308/ Don't be Fooled! A Lesson in Unmasking Pseudoscience - https://www.youtube.com/watch?v=1IWCmFgThQA     Connect with Dr. Nick Norwitz: Twitter: https://x.com/nicknorwitz  Instagram: https://www.instagram.com/nicknorwitz/ YouTube: https://www.youtube.com/channel/UCLTZUJSEulehPtF_ytFiU_A?sub_confirmation=1 Newsletter: https://staycuriousmetabolism.substack.com/   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/  

Link to Buck's Results: https://drive.google.com/file/d/19BJaZNYwBxlPx4nR9695Q2NC3nNpgW6y/view?usp=sharing  https://drive.google.com/file/d/1br1ikAJKmgKev9X3jkS7nUPdXpAqMzYd/view?usp=sharing Section 1: Overview of Cholesterol Metabolism Cholesterol in the Body: Cholesterol is essential for cell membrane integrity, hormone synthesis, and bile acid production. It is produced endogenously in the liver and absorbed exogenously from dietary sources. Endogenous Production: Cholesterol is synthesized in the liver through the mevalonate pathway. Key intermediates: Lathosterol and Desmosterol, indicators of cholesterol production rate. Exogenous Absorption: Dietary cholesterol is absorbed in the intestines along with plant sterols like Beta-sitosterol and Campesterol. These sterols compete with cholesterol for absorption, reflecting dietary cholesterol absorption levels. Section 2: Detailed Analysis of the Test Components Production Markers: Lathosterol: Precursor in the cholesterol biosynthesis pathway. Elevated levels indicate increased hepatic cholesterol synthesis (overproduction). Example: Lathosterol level of 329 µmol x 100/mmol in my study indicates hyperactive cholesterol production. Desmosterol: Another precursor in the synthesis pathway, contributing to total cholesterol production. High levels reinforce the diagnosis of increased cholesterol production. Example: Desmosterol level of 74 µmol x 100/mmol in my study supports elevated production. Absorption Markers: Beta-sitosterol: Plant sterol absorbed in the intestines, competes with cholesterol. High levels suggest increased absorption of dietary cholesterol. Example: Beta-sitosterol level of 120 µmol x 100/mmol indicates borderline absorption. Campesterol: Similar to Beta-sitosterol, reflects cholesterol absorption efficiency. Elevated levels indicate increased absorption. Example: Campesterol level of 113 µmol x 100/mmol within normal limits but suggests absorption could be a factor. Cholesterol Balance Score: Ratio of production to absorption markers. A higher score indicates predominant cholesterol production; a lower score indicates absorption as the main issue. Example: Score of 2.4 suggests overproduction is the dominant issue. Section 3: Clinical Implications and Treatment Strategies (10 minutes) Frequency of Overproduction vs. Overabsorption: Common to see patients with either overproduction or overabsorption, but less commonly both. Overproducers: Significant portion of hypercholesterolemia patients, especially those with genetic conditions like Familial Hypercholesterolemia. Overabsorbers: Often have high-cholesterol diets or genetic predispositions. Treatment Implications: Overproducers: Statins are first-line treatment; they inhibit HMG-CoA reductase in cholesterol synthesis. Overabsorbers: Ezetimibe, which inhibits intestinal cholesterol absorption, can be effective. Combination Therapy: Considered for mixed dyslipidemia cases. Case Examples: Example of a patient with high production markers but borderline absorption: Statin therapy may be appropriate, with potential addition of Ezetimibe. Example of a patient who is a high absorber but not a high producer: Dietary changes and Ezetimibe might suffice without statins. Section 4: Physiological Mechanisms and Genetic Considerations Pathophysiology of Cholesterol Production: Overproduction may result from genetic mutations (LDL receptor or PCSK9) or conditions like insulin resistance. Pathophysiology of Cholesterol Absorption: Increased absorption could be due to genetic polymorphisms (NPC1L1 gene), leading to higher dietary cholesterol absorption. Section 5: Practical Application in Clinical Practice Incorporating the Test into Clinical Workflow: Integrate the Boston Heart Cholesterol Balance Test for patients with unexplained hypercholesterolemia or non-responders to standard therapy. Tailor treatment based on whether a patient is an overproducer, an overabsorber, or both. Patient Communication: Explain test results in an understandable way, emphasizing personalized treatment plans.

Welcome to Protecting Your Nest with Dr. Tony Hampton. Michael Papahronis is a patient of Dr. Tony's. He has had Type-1 Diabetes for 27 years and has been a middle school teacher for over 20 years. He is a husband and father and has had his life saved and changed by the keto diet. This episode is part 2 of this conversation. In this discussion, Dr. Tony and Michael talk about: (02:01) How Michael has been able to stay out of the hospital using diet and lifestyle tools (12:42) How using a CGM has changed Michael's life (19:50) Other technology that is useful for diabetics (24:20) Some very helpful resources for Type 1 diabetics (see Additional Links below) (30:22) Measuring A1c levels (33:46) Michael's weight loss journey (37:04) How dairy is actually addictive (39:11) Making good dietary choices for your kids to protect against the development of Type 1 diabetes (46:35) Statin drugs (53:06) Migraines and diet Thank you for listening to Protecting Your Nest. For additional resources and information, please see the links below.   Links:   Additional Links: Management of Type 1 Diabetes With a Very Low-Carbohydrate Diet Type 1 Grit (Facebook Group) Dr. Bernstein's Diabetes Solution Dr. Keith Runyan's Books Dr. Roshani Sanghani's Book Nina Teicholz's Books Gary Taubes' Books   Dr. Tony Hampton: Linktree Instagram Account LinkedIn Account Ritmos Negros Podcast Q Med Symposium for Metabolic Health Lectures How Waking Up Every Day at 4:30 Can Change Your Life

Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I'm a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients. This podcast discusses common beliefs and skepticism around cholesterol and statin medications. The host, Dr. Warrick Bishop, a cardiologist, addresses misconceptions such as cholesterol not being harmful, heart disease not being caused by high cholesterol, and saturated fats not being harmful. He explains that while cholesterol levels alone don't directly predict plaque buildup, lowering cholesterol is crucial for those at high risk of heart disease. Dr. Bishop also responds to claims that the cholesterol hypothesis is incorrect, that statin side effects are underreported, and that statins deplete vital nutrients. He emphasizes that while lifestyle changes are important, medication is often necessary for those at high risk. Overall, the podcast provides a balanced perspective on the complex relationship between cholesterol, heart disease, and statin medications.

Circulation 68, No. 5, 939-950, 1983Background  Coronary artery bypass surgery (CABG) had grown in popularity through the 1970s and 1980s. By 1981, approximately 159,000 bypass surgeries had been done.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber.The goal of the CASS trial was to rigorously evaluate the effect of surgical vs medical therapy on total mortality in well-defined subsets of patients with coronary artery disease.Patients Eligible patients had to be 65 years of age or below and have angina that was Canadian Cardiovascular Society class I or II with or without a history of myocardial infarction, or had to have a well-documented MI more than 3 weeks before randomization. Clinical criteria for exclusion were prior CABG, unstable or progressive angina, angina more severe than class II (angina occurring after climbing one flight of stairs or walking two blocks is class III), congestive heart failure (New York Heart Association class III or IV), a coexisting illness that would increase the likelihood of death within 5 years, and a variety of practical exclusions that might limit active participation during follow-up.Angiographic requirements for participation in the trial included the presence of significant operable coronary artery disease, defined as either 70% or greater reduction in the diameter of the right, left anterior descending, or left circumflex coronary artery, or 50% or greater reduction in the diameter of the left main coronary artery. Patients with 70% or greater luminal diameter reduction of the left main were excluded. Also excluded were patients with LVEF (measured by left ventriculography) of less than 35% or those patients who required valve surgery or LV aneurysm repair.Baseline Characteristics There were 390 patients randomized in both the surgical and medical arm. The mean age was 51 years; 90% were males and 98% were White. Approximately 60% had previous MI, 30% had hypertension and only 3% had congestive heart failure. About 40% were smokers.Angiographic criteria were well matched—27% had one-vessel disease, 38% had two-vessel disease, and about a third had three-vessel disease. Nearly a third of patients in both groups had proximal LAD disease. The LVEF was more than 50% in 73-74% of patients in both groups. The LVEF was less than 50% in a fifth of patients in both arms.Procedures CASS authors were quite clear in the screening and randomization process. Slightly more than 16,600 patients were screened for participation in the trial at 11 centers. Figure 1 in the manuscript shows the reasons for exclusion, which included normal or minimal coronary disease (28%), Class 3 or 4 angina (36%), and left main disease more than 70%n (1.5%). Other exclusions totaled 16%.Ultimately there were 2099 patients eligible to be randomized, however, 1319 patients were not included in the trial due to physician preference.Randomization was stratified by clinical site, number of diseased vessels, and ejection fraction within three different clinical subgroups. Patients with angina and ejection fractions of at least 0.50 were randomized within group A (n =514), those with angina and EF less than 0.50 were randomized within group B (n=106) and those free of angina after well-documented MI were randomized within group C (n=160).A total of 954 distal anastomoses were constructed in 357 patients in the surgical group, an average of 2.7 per patient. A total of 334 distal anastomoses were evaluated in the 129 patients; 90% of the grafts were open, 97% of patients had at least one open graft, and in 81% of patients all grafts were patent. Medical therapy consisted mostly of nitrates, and beta-blockers. Statin drugs were not available during the trial. Endpoint The primary endpoint was all-cause mortality. It was assessed with the intention-to-treat method. Results There were no significant differences in mortality.At 5 years, the average annual mortality rate in patients assigned to surgical treatment was 1.1%. The annual mortality rate in those receiving medical therapy was 1.6%. Expressed differently, the rate of death at 5 years was 9.2% in the medical group versus 7.4% in the surgical group. Annual mortality rates in patients with single-, double-, and triple-vessel disease who were in the surgical group were 0.7%, 1.0%, and 1.5%; the corresponding rates in patients in the medical group were 1.4%, 1.2%, and 2.1%.There were also no significant differences in survival when patients were grouped according to degree of coronary artery disease (number of vessels) or EF or by a combination of diseased vessels and EF.Crossovers did occur. Approximately 23% of the 390 patients assigned to the medical group had surgery during the follow-up period (4.7% per year). Of the patients assigned to surgery, 31 of 390 patients (8%) did not have surgery.Conclusions The CASS authors write in the abstract of the manuscript that they observed excellent long-term survival in both groups and that for patients similar to those in the trial, surgery could be deferred until symptoms worsen.The CASS trial had caveats. First was that the 780 patients enrolled in the trial were highly selected from a total of more than 16,000 patients in the registry. The CASS registry revealed widely disparate annual mortality in patients managed medically, ranging from 1.3% for those with single-vessel disease and normal EF to 12.5% in those with three-vessel disease and impaired EF. Another caveat was the lower-than-expected annual mortality in the medical arm of only 1.6%. This was lower than previous surgery trials (3.3% noted in the European Collaborative Study and 4.3% reported in the Veterans Administration Study). CASS authors estimated a 2-4% annual mortality. This reduces the power to find differences in the two groups.It is interesting however, that for the 1319 patients in whom their physician declined randomization, the outcome in those treated medically was similar to that reported in the randomly assigned patients who received medical therapy.In conclusion, as early as the 1980s, the CASS study showed that stable coronary artery disease was quite stable, and that revascularization in selected patients did not improve survival over medical therapy. Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe

A clinical debate about the benefits versus the risks of deprescribing statins in adults over the age of 75 in both primary and secondary preventionPresented by: Megan Gross, PharmD, PGY1 Pharmacy Resident, SSM Health Monroe ClinicStephanie Garvin, PharmD, PGY2 Ambulatory Care Resident, SSM Health Monroe Clinic

What does the body of evidence say on malaria? Your favourite travel destination may be a malaria hot zone: we discuss how to prepare. Plus: a strange FDA application to use MDMA to treat PTSD, and have statins been overprescribed?   A Block: Malaria (0:58) History; the parasite's life cycle; how many people are affected by malaria; symptoms; how to diagnose it; how to treat it; prevention. B Block: Ecstasy for PTSD (35:46) An advisory committee for the FDA has raised many concerns about a company's application to use MDMA (ecstasy, molly) as part of psychotherapy for post-traumatic stress disorder. C Block: Statin Overprescription (46:08) A new risk calculator is classifying fewer people as needing statins. * Theme music: “Fall of the Ocean Queen“ by Joseph Hackl * Assistant researcher: Aigul Zaripova To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/. To make a one-time donation to our show, you can now use PayPal! https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE Patrons get a bonus show on Patreon called “Digressions”! Check it out! Chris' book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause-cancer   References: 1) WHO fact sheet on malaria: https://www.who.int/news-room/fact-sheets/detail/malaria History of malaria: 2) https://doi.org/10.3390/ijerph7020675 3) https://doi.org/10.1007/s11230-004-6354-6 4) DOI: 10.1111/j.1365-2141.2008.07085.x 5) https://doi.org/10.1179/135100003225002952 6) https://doi.org/10.1038/hdy.2011.16 7) doi: 10.1038/s41598-018-19554-0  8) https://www.ncbi.nlm.nih.gov/books/NBK215638/    9) Plasmodium parasite life cycle: https://www.cdc.gov/dpdx/malaria/index.html    Malaria epidemiology: 10) https://www.canada.ca/en/public-health/services/catmat/canadian-recommendations-prevention-treatment-malaria/chapter-1-introduction.html  11) https://www.who.int/news-room/fact-sheets/detail/malaria  12) https://apps.who.int/malaria/maps/threats/# 13) https://www.who.int/publications/i/item/9789240086173  14) DOI: 10.15585/mmwr.mm7236a1   15) https://emergency.cdc.gov/han/2023/han00496.asp  16) https://www.canada.ca/en/public-health/services/catmat/appendix-1-malaria-risk-recommended-chemoprophylaxis-geographic-area.html    How to diagnose malaria: 17) https://www.cdc.gov/dpdx/resources/pdf/benchAids/malaria/Pfalciparum_benchaidV2.pdf  18) https://www.cdc.gov/dpdx/resources/pdf/benchAids/malaria/Pvivax_benchaidV2.pdf  19) https://www.cdc.gov/dpdx/resources/pdf/benchAids/malaria/Povale_benchaidV2.pdf  20) https://www.cdc.gov/dpdx/resources/pdf/benchAids/malaria/Pmalariae_benchaidV2.pdf    How to prevent malaria: 21) https://www.who.int/groups/vector-control-advisory-group/summary-of-new-interventions-for-vector-control/lethal-house-lures  22) DOI: 10.1016/S0140-6736(24)00004-7 23) https://www.bbc.com/news/world-africa-68037008 24) DOI: 10.1056/NEJMoa2026330 25) DOI: 10.1016/S1473-3099(23)00368-7 26) DOI: https://doi.org/10.1016/S1473-3099(22)00442-X   27) Dr. Andrea Love's article about DEET and insect repellents for Immunologic: https://immunologic.substack.com/p/essential-oils-are-not-chemical-free?publication_id=2109759&post_id=145493032&isFreemail=true&r=5o22t 28) Ada McVean's article about insect repellents for the McGill OSS: https://www.mcgill.ca/oss/article/health-technology/why-mosquitos-bite-you-and-how-make-them-stop 29) FDA advisers vote against medical use of ecstasy: https://www.science.org/content/article/fda-advisory-panel-rejects-mdma-ptsd-treatment 30) Elizabeth Conney's STAT article on new cardiovascular risk calculator for statin prescriptions: https://www.statnews.com/2024/06/10/cardiovascular-disease-statins-aha-guidelines/   It's Not Twitter But It'll Do: 1) Jonathan's interview on the Rethinking Wellness podcast: https://rethinkingwellness.substack.com/p/why-you-probably-dont-have-a-leaky

In this episode, Dr. Joel Kahn pays tribute to two influential figures, Drs. Endo and Mosley, who passed away this month. He also delves into the benefits of adding more tomatoes and choline-rich foods to your diet for heart health. Plus, even plant-based junk food is still junk food, and Dr. Kahn reminds us why it's best to avoid it. On a hopeful note, a new study suggests that the supplement nicotinamide riboside may improve leg circulation. You can find it here: Tru Niagen® 300 mg - 90 Vegetarian Capsules.  The main focus of this episode is the new PREVENT score calculator, which helps healthcare professionals determine who might benefit from statin therapy for lowering cholesterol. Dr. Kahn was recently interviewed on national TV to discuss this significant development. Understanding this tool is crucial, and you can explore it here: PREVENT Calculator.

A lot has been going on for me, and I wanted to give you a look into what is going on. First things first, I did a video a while back about some health problems that I was having. I was having some strange Premature Ventricle Contractions that took me to a cardiologist. The cardiologist was concerned about my high blood pressure and my cholesterol and triglycerides. Not wildly uncommon for someone in my demographic. I was put on two blood pressure medicines and two statins. The first statin gave me horrible leg pains, to the point where I couldn't even walk up and down stairs, so I was put on a different Statin mix that I tolerated a little better.The blood pressure medicine made me retain a bunch of water, to the point where I was getting really bloated and my clothes didn't fit right, so I was put on a diuretic/blood pressure combo in addition to the original blood pressure medicine I was on. I also had a high A1C reading of 6.8, which isn't off the charts, but puts you in the range of the start of diabetes. Below 6 is where they like it to be. This tests kind of give you a sense of your average blood glucose numbers over a period of time, but to fully diagnose you with diabetes, they like to have a second confirming test.So fast forward several months and I am having issues with what I believe to be the diuretic. Thirsty all the time, peeing several times during the night. Eventually, it got so bad, I was drinking 4 gallons of water a day and peeing 4-5 times at night and pretty much non-stop and with great urgency during the day. I had also lost about 16 pounds in just a few weeks. My vision had also been getting really bad, but I just chalked that up to needing a new prescription.So it comes time to take another A1C test before an appointment. This time the test cam back at 13.2, which is kind of off the charts. I knew this was something concerning, because both my Cardiologist and my primary care physician called me right away, which never happens these days. My Primary care physician wanted to get me on insulin and get me to an endocrinologist right away, but I suggested that it was such a big jump that I should take the A1C test again again, because it was too big of a jump. So I asked for Metformin to get started and a glucose test kit. So I got that, I started taking the Metformin and I tested my blood, which was in the 300s fasting. For reference you are supposed to be in the 70-100 range. That's when I realized I might have some issues.I messaged my doctors saying that we may need to be more aggressive with the treatment, but later that night, before anyone was able to get back to me, my blood sugar went up to 485. People had been telling me that if my glucose gets over 400 I should go straight to the hospital, so I got my wife out of bed and had her drive me, even though I was feeling OK oddly. At the hospital, they took one look at my blood work and they told me I wasn't going home.I was there for 3 days while they got everything under control. Lots of blood tests, finger sticks and insulin 4+ times a day. So now I am out, my numbers are much better, and I haven't had to be as aggressive with the treatment. The great news is that fixing the diabetes, seems to have fixed the high blood pressure, the vision, the peeing and the high triglycerides.Now I didn't have to make many life changes, I have long been a pescatarian, and had a generally low-carb diet. I miss my apples, grapes and bananas, but I am doing good with other things and I am using the Truvia, brown sugar substitute in my tea, which is a nice change from all the sugarless tea I had been drinking.So if anyone wants to be my dia-buddy, I am open.Click Here to SubscribeOccasionally we share links to products we use. As an Amazon Associate we earn from qualifying purch

I specialise in helping women overcome their health challenges so they can thrive at any age. Issues clients come to me with are usually a combination of: Fatigue Digestive trouble (gas, bloating, constipation) Mood issues (anxiety, irritability) Sleep problems PMS, if still cycling Brain fog or diminished cognitive capacities Excess "stubborn" weightLearn more about how I can help you and request a free intro call with me here: https://christianyordanov.com/womens-health-transformationMy latest book on longevity, How to Actually Live Longer, Vol1.: https://amzn.to/3OnZJGlFollow me on Instagram for informational clips and other health content: https://www.instagram.com/christian_yordanov/

Fat can have a bad reputation, but certain fats are essential for the healthy functioning of your brain. Between government guidelines, fad diets, and our endless social feeds, nutrition advice overload has left us all a bit lost with how to incorporate healthy fats into what we eat. In this episode, we discuss: • The different kinds of fats (saturated vs. unsaturated) and which ones we actually need to consume • The myth that “because your brain is primarily made of fat, it thrives on a high-fat diet” • How the cardiovascular damage caused by saturated fats can increase the risk of cognitive decline and dementia • All the tasty ways you can get more healthy, unsaturated, essential fats into your meals We welcome esteemed nutrition scientist Dr. Alan Flanagan back to the show, to explore the history of research into the impact of fats and how it shaped one of the most robust bodies of evidence in all of science. We're also joined by Dr. Danielle Belardo, renowned cardiologist and science communicator, to talk about the interplay between heart health, brain health, and fats, the controversy around statins, the low-down on LDL cholesterol, and the future of cardiovascular interventions. ‘Your Brain On' is hosted by neuroscientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... FATS' • SEASON 2 • EPISODE 4   LINKS Dr. Alan Flanagan: Alan on Instagram: https://www.instagram.com/thenutritionaladvocate Alinea Nutrition: https://www.alineanutrition.com/   Dr. Danielle Belardo: Dr. Belardo's website: https://www.daniellebelardomd.com/ Practical, Evidence-Based Approaches to Nutritional Modifications to Reduce Atherosclerotic Cardiovascular Disease: https://pubmed.ncbi.nlm.nih.gov/35284849/   FOLLOW US Join the NEURO Academy: NEUROacademy.com Instagram: @thebraindocs Website: TheBrainDocs.com More info and episodes: TheBrainDocs.com/Podcast   REFERENCES Scientific articles discussed in this episode: Mensink, Ronald P., and World Health Organization. Effects of saturated fatty acids on serum lipids and lipoproteins: a systematic review and regression analysis. World Health Organization, 2016. Okereke, Olivia I., et al. “Dietary fat types and 4‐year cognitive change in community‐dwelling older women.” Annals of neurology 72.1 (2012): 124-134. Simian Diet paper: Kendall, Cyril WC, and David JA Jenkins. “A dietary portfolio: maximal reduction of low-density lipoprotein cholesterol with diet.” Current atherosclerosis reports 6.6 (2004): 492-498. Solomon, Alina, et al. “Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later.” Dementia and geriatric cognitive disorders 28.1 (2009): 75-80. Morris, Martha Clare, et al. “Dietary fats and the risk of incident Alzheimer disease.” Archives of neurology 60.2 (2003): 194-200. Keys, Ancel, Joseph T. Anderson, and Francisco Grande. “Prediction of serum-cholesterol responses of man to changes in fats in the diet.” Lancet 273 (1957): 959-966 Anitschkow, N. N., and S. Chalatow. 1913. Ueber experimentelle Cholesterinsteatose und ihre Bedeutung fur die Entstehung eini- ger pathologischer Prozesse. Zentralbl. Allg. Pathol. 24: 1–9. Keys, Ancel, et al. “The seven countries study: 2,289 deaths in 15 years.” Preventive medicine 13.2 (1984): 141-154. Sherzai, Ayesha Z., Alexander N. Sherzai, and Dean Sherzai. "A systematic review of omega-3 consumption and neuroprotective cognitive outcomes." American Journal of Lifestyle Medicine 17.4 (2023): 560-588. Rajan, Kumar B., et al. "Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults." Neurology 102.7 (2024): e209168. Olmastroni, Elena, et al. "Statin use and risk of dementia or Alzheimer's disease: a systematic review and meta-analysis of observational studies." European journal of preventive cardiology 29.5 (2022): 804-814.

Commentary by Dr. Valentin Fuster

Tune in to the latest episode of the Crackin' Backs Podcast where we welcome Dr. Jonny Bowden, a renowned expert in functional nutrition and a dynamic force in the fitness world. From overcoming personal challenges to achieving a PhD in functional nutrition, Dr. Bowden has dedicated his life to asking "why" and discovering how to live healthier through science-backed methods. In this deep dive, we explore the emerging field of genetic testing and its implications for personalized health strategies. Dr. Bowden shares his critical views on statins, challenging the conventional wisdom about cholesterol and its management. Expect a thought-provoking discussion on the need for a paradigm shift in how we perceive and treat heart health.For our listeners navigating their prime in their 50s and 60s, Dr. Bowden reveals his favorite diet strategies that promise vitality and longevity. Younger athletes aren't left out; he addresses common misconceptions about diet, focusing on the balance between carbohydrates and protein, and tips for enhancing energy and sleep.Moreover, Dr. Bowden weighs in on the debate between genetics and the environment in shaping our health and responds to questions about the role of ancestry in determining the ideal diet. He also evaluates recent studies on the benefits of Quercetin in reducing arterial plaque, providing actionable advice for heart health.Confronting the challenges of sourcing authentic, farm-to-table food, Dr. Bowden offers practical solutions for those striving to incorporate real food into their diets.This episode is packed with insights for anyone interested in optimizing their health through informed, innovative approaches.Don't miss this transformative conversation with Dr. Jonny Bowden on the Crackin' Backs Podcast—where health myths meet their match. To learn more about Dr. Bowden, to purchase his books and possibly book a consultation with him. Click HEREWe are two sports chiropractors, seeking knowledge from some of the best resources in the world of health. From our perspective, health is more than just “Crackin Backs” but a deep dive into physical, mental, and nutritional well-being philosophies. Join us as we talk to some of the greatest minds and discover some of the most incredible gems you can use to maintain a higher level of health. Crackin Backs Podcast

Statin Nation: an inside look at how bad science and good marketing transformed cholesterol into a money-making disease. In this jaw-dropping episode, Dr. Sandstrom investigates the shady practices big pharma used to convince millions of people to take cholesterol drugs for life. Is lowering cholesterol really the key to avoiding heart attacks? The truth will shock you. For complete show notes visit my website https://www.davidsandstrom.com/139 0:00 Introduction 4:55 Cholesterol's crucial role in our physiology 10:33 Statin side effects, including high blood sugar and cognitive issues. 15:24 Pharmaceutical industry's marketing strategies and their impact on public health. 26:47 Causes of atherosclerosis, including damage to artery walls and buildup of plaque. 37:22 Metabolic health, lifestyle changes for heart health. 41:58 Twitter language predicting heart disease mortality. David's Book: The Christian's Guide to Holistic Health 

Episode #311. Some people follow a ketogenic diet seeking to lose weight, feel more energised, or gain control over their eating habits. Others may turn to this diet in an effort to treat their epilepsy, bipolar disorder, or diabetes. Regardless of their reasoning for adopting this eating pattern, a key question remains: can high LDL cholesterol levels on a ketogenic diet be safe? Today I sit down with Dr William Cromwell, MD and Dave Feldman to explore this question. In this discussion, Dr William Cromwell and Dave Feldman share their professional opinions on whether high cholesterol on a keto diet is a problem. We investigate where their opinions align and where they differ, where Dave's hypotheses diverge from the norm, and what we do and don't know with the available evidence. We also explore the significance of ApoB, lifespan and healthspan considerations, research Dave is currently conducting, and much more. Specifically, we discuss: Intro (00:00) Dr. William Cromwell: Background as a Lipidologist and LDL Research (01:54) Dave Feldman's Ketogenic Diet and Elevated LDL Experience (05:34) Unpacking the Lipid Hypothesis and Cardiovascular Risk (12:30) The history and evolution of the lipid hypothesis (20:40) The role of apoB lipoproteins in atherosclerosis (23:39) Factors beyond apoB involved in atherosclerosis and mortality risk (31:59) The complexity of interpreting mortality data in the context of apoB (41:40) Macrophages and the process of atherosclerosis (44:00) Beyond ApoB: Metabolic Vulnerability, Inflammation and Mortality Risk (52:57) Transcytosis: A New Perspective on LDL Movement and Atherosclerosis (1:10:36) Exploring Low Cholesterol Impacts and Genetic Disorders (1:17:30) Macrophage function and phenotype in the context of different drivers of high apoB (1:22:30) Defining Lean Mass Hyper-responders in the Context of a Ketogenic Diet (1:31:40) Investigating PCSK9 and Its Effects on Healthspan (1:38:00) Assessing cardiovascular risk in lean mass hyper-responders (1:43:50) Statin safety, adverse effects, and patient reluctance (2:01:54) Ketogenic Diets and Elevated LDL: Balancing Individual Risks and Benefits in the Absence of Long-term Data (2:10:40) Insulin Resistance, ApoB, and Cardiovascular Risk: Navigating the Challenges in Assessment and Imaging (2:18:12) Lean Mass Hyper-responder Study: Design, Recruitment, and Eligibility Criteria (2:32:45) Closing Perspectives on Research and Dietary Options (3:04:47) Outro (3:06:42) Connect with Dr William Cromwell on Twitter/X, LinkedIn, and his website, https://www.mylipid.com/. Discover more of his work with Precision Health Reports on Twitter/X, LinkedIn, Facebook, Instagram, and at https://precisionhealthreports.com/. Connect with Dave Feldman on Twitter/X, YouTube, and Instagram, and discover more of his work at https://citizensciencefoundation.org/, https://ownyourlabs.com/, and https://cholesterolcode.com/. This episode is brought to you by: InsideTracker If you want to improve your health, you need to measure where you're currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Get a 20% discount on your first order at insidetracker.com/simon. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet's best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Sun Home Saunas Invest in your body and mind with Sun Home Saunas, pioneers in crafting premium saunas and cold plunges. Safe, effective, research-backed wellness tools to improve cardiovascular health, offer psychological benefits, and reduce muscle soreness. Head to sunhomesaunas.com/theproof for $300 off your purchase.

Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I'm a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients. Dr. Warrick Bishop discusses statin intolerance and the nocebo effect in his podcast. He describes a study that found 78% of patients believed to be statin intolerant were actually able to tolerate the medications. Another study found 72% of self-reported statin intolerant patients could take statins without issues when blinded to the therapy. A trial called Samsung found that 90% of reported muscle symptoms were from the nocebo effect rather than the statins themselves. Dr. Bishop concludes that lowering statin dosage frequency or adding other drugs can help many more patients achieve health benefits from cholesterol lowering therapies.

Welcome to Protecting Your Nest with Dr. Tony Hampton. Dr. Robert Lufkin is a physician/medical school professor (UCLA and USC) focusing on the applied science of health, longevity, and consciousness. After reversing chronic disease and transforming his life he is making it his mission to help others do the same. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in six languages. Robert has given invited lectures/keynotes around the world, and was named one of the ‘100 Most Creative People in Los Angeles' by Buzz Magazine. His latest book “Lies I Taught In Medical School” has just been released. In this discussion, Drs. Tony and Robert talk about: (03:31) Why Dr. Robert chose to go into the field of Radiology and how he implements metabolic health in this field (06:20) Dr. Robert's own personal struggles with chronic disease and how these struggles shaped and changed his thinking on metabolic health and the root cause of disease (08:37) Why Dr. Robert wrote his most recent book, Lies I Taught in Medical School (13:21) Why Dr. Robert switched from vegetarianism/veganism to a more animal-based diet (15:26) The most important aspects to focus on in order to avoid chronic disease risk factors (17:25) The unfortunate lack of exposure that most doctors have to resources on metabolic health and dietary intervention (23:19) Progress in the field of longevity and how the average person can apply the findings of this field to their own life (32:25) A recent abstract from a non-peer-reviewed paper suggesting that intermittent fasting causes 91% higher risk of heart disease (36:14) Lies commonly taught in medical school about treating Alzheimers patients (43:16) Lies commonly taught in medical school about treating cancer (46:53) Lies commonly taught in medical school about treating diabetes (50:17) Lies commonly taught in medical school relating to Statin drugs (53:05) Dr. Robert's philosophy of guiding patients toward a diet that is metabolically healthy and sustainable for a given person (56:27) Basic recommendations for being healthy and achieving longevity Thank you for listening to Protecting Your Nest. For additional resources and information, please see the links below.   Links:   Dr. Paul Merik Interview on Treating Cancer The Alzheimers Antidote (book by Amy Berger) Brain Energy (book by Dr. Chris Palmer) Change Your Diet, Change Your Mind (book by Dr. Georgia Ede)   Dr. Robert Lufkin: Website Twitter Instagram Linktree   Dr. Tony Hampton: Linktree Instagram Account LinkedIn Account Ritmos Negros Podcast Q Med Symposium for Metabolic Health Lectures How Waking Up Every Day at 4:30 Can Change Your Life

蒼藍鴿使用的保健品牌「藥師健生活」: ⟡ 輸入優惠碼「bluepig」享全品項95折優惠! ⟡ 點我購買 ▶️ https://www.phargoods.com/ --- ⟡ 支持蒼藍鴿產出Podcast ➤ https://open.firstory.me/join/bluepigeon0810 ⟡ 信箱 ➤ bluepigeonn@gmail.com --- 【各段重點】 00:00 老人睡眠時數較少的原因? 02:49 寶林茶室「米酵菌酸」中毒事件 12:09 小林製藥「紅麴」中毒事件 15:38 紅麴保健食品＆降膽固醇藥物比較 #失眠 #小林製藥紅麴 #寶林茶室 #睡眠 #睡眠時數 #米酵菌酸 #食物中毒 #粿條 #粄條 #唐菖蒲伯克氏菌 #粒線體 #多重器官衰竭 #洗腎 #洗肝 #玉米粉 #椰子製品 #玉米製品 #澱粉 #氰化物 #解藥 #死亡率 #紅麴 #膽固醇 #Statin --- ⟡ 更多醫學知識： 蒼藍鴿著作 ➤ https://ppt.cc/ffUrkx Instagram ➤ https://reurl.cc/ygvba8 Youtube ➤ https://reurl.cc/gm6bb7 Line Voom ➤ https://ppt.cc/fW8IVx Tik Tok ➤https://ppt.cc/fBehOx Powered by Firstory Hosting

Take a deep dive into the heart of midlife cardiovascular wellness with this important episode of "Age Better," where host Barbara Hannah Grufferman talks with Dr. Melissa Tracy, a top-tier cardiologist from the RUSH University Medical Center. Dr. Tracy is also the Medical Director of the Cardiac Rehabilitation Program at RUSH.   Dr. Tracy gives a masterclass on statins - those powerhouse medications at the forefront of cholesterol management and heart disease prevention. But the question that lies at the core of this discussion is one that resonates with millions: Who really needs to be on statins? By tuning in, you'll get the knowledge and tools you need to make the decision that is right for you.   KEY TAKEAWAYS:  Understanding Statins: Learn how these powerful medications aid in reducing cholesterol and preventing cardiovascular disease.  Postmenopause and Heart Health: Discover the unique impact of statins for women in midlife.  Shared Decision-Making: The importance of patient-doctor collaboration in deciding if statins are right for you.  Coronary Calcium Score: Uncover how this test is crucial in assessing cardiovascular risks.  Side Effects & Alternatives: Insights into common side effects of statins and who should avoid them, plus a look at natural supplements and other cholesterol management strategies.  Personalized Healthcare: Dr. Tracy emphasizes individualized treatment plans and the role of lifestyle changes alongside statins.  Future-Focused Discussion: A sneak peek into ongoing assessments and evolving conversations in heart health management.    KEY LINKS:  Learn More About Dr. Melissa Tracy: https://doctors.rush.edu/details/1183  What is Cardiac Rehabilitation? https://www.kevinmd.com/2024/02/a-people-first-approach-to-cardiac-rehabilitation.html  USNews+WorldReport Article: https://www.usnews.com/news/health-news/articles/2024-03-05/statin-meds-cholesterol-what-you-need-to-know  Alternatives to Statins Referenced During the Episode:   Ezetimibe: https://www.mayoclinic.org/drugs-supplements/ezetimibe-oral-route/description/drg-20067172  Bempedoic Acid: https://www.mayoclinic.org/drugs-supplements/bempedoic-acid-oral-route/side-effects/drg-20484223?p=1  PCSK9 inhibitors: https://www.medicalnewstoday.com/articles/pcsk9-inhibitor#definition  Whether you're on a statin already, or giving it serious consideration … this episode will help you make the decision that is right for you.  Learn More About ‘Age Better' Podcast:  Age Better podcast delves into a diverse range of topics, including finance, work, health, fitness, style, makeup, hair, nutrition, travel, relationships, sex, and more.   Listen and Subscribe   To join this adventure, remember to subscribe or follow the "Age Better with Barbara Hannah Grufferman" podcast on platforms like Apple Podcasts, Spotify, and YouTube. Yep, you can watch it or just listen!   Share Your Ideas and Questions   Your questions have spurred many episodes, so please keep them coming! Share your ideas for topics and guest suggestions at agebetterpodcast@gmail.com  Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode discusses the use of statin drugs for high cholesterol and their potential risks and side effects. Jen shares her personal experience with her father's healing journey and the role of statins in his health issues. The conversation covers the importance of understanding heart disease and cholesterol, the impact of inflammation and liver health, and the benefits of using food as medicine to reduce heart disease risk. Jen also provides tips for helping reluctant loved ones make dietary changes and emphasizes the importance of proper testing to wean statin medication and nutritional support. Takeaways Statin drugs are commonly prescribed for high cholesterol but can have potential risks and side effects. Understanding heart disease and cholesterol is crucial for making informed decisions about statin use. Inflammation and liver health play significant roles in heart disease. Using food as medicine and making dietary changes can help reduce heart disease risk. Proper blood testing and nutritional support are essential for managing heart disease and weaning off statins. Show notes: STATIN BLOG: https://www.middaypigeon.com/complete-blog/statin-secrets   HORMONE HEALING GUIDE: https://fantastic-trailblazer-5737.ck.page/be8ab6b193  ONE DAY DETOX GUIDE: https://www.inspirehealthbyjen.com/onedaydetox  MEALS TO HEAL: https://www.inspirehealthbyjen.com/inspire-products/meals-to-heal-recipe-ebook  FREE NON-TOX LIFESTYLE GUIDE: https://fantastic-trailblazer-5737.ck.page/ff2cd2a562  IN-HOME INFRARED THERAPY: https://www.inspirehealthbyjen.com/infrared-therapy GUT CLEANSE GUIDE: https://fantastic-trailblazer-5737.ck.page/c3a5591584  SYMPTOMLESS FOOD AS MEDICINE COURSE: https://www.inspirehealthbyjen.com/symptomless-course-info  Have a question? Send a request and we may feature it on a future episode!: https://forms.gle/bbpYJKTPhmsezYs3A   WORK WITH JEN 1-1 https://www.inspirehealthbyjen.com/discovery-call CONNECT WITH JEN: https://www.inspirehealthbyjen.com/work-with-jen  INSPIRE HEALTH FACEBOOK GROUP: https://www.facebook.com/groups/inspirehealthhealing/ FOLLOW JEN ON IG: https://www.instagram.com/inspirehealthbyjen/  Read my Google reviews! https://tinyurl.com/googlereviewsihbj    Free Guide(s): Non-Tox Lifestyle Guide: https://fantastic-trailblazer-5737.ck.page/ff2cd2a562  One Day Detox Recipes: https://www.inspirehealthbyjen.com/onedaydetox  Full Moon Meditation: http://www.inspirehealthbyjen.com/subscribe-for-full-moon-meditation Energy Healing Audio: https://www.inspirehealthbyjen.com/energy-healing-audio-download  Gut Cleanse Guide: https://fantastic-trailblazer-5737.ck.page/c3a5591584  Find Out More: www.inspirehealthbyjen.com  Blog: www.middaypigeon.com   If you have questions or would like me to help you get started… Let's get in touch and begin your true path of healing today. Your body and your mind will eternally thank you!

Heart Surgeon and best selling author Dr. Phil Ovadia discusses the foods and lifestyle factors driving a new wave of early-onset heart disease. Sponsored: Support your Intermittent Fasting lifestyle with the Berberine Fasting Accelerator by MYOXCIENCE: https://bit.ly/berberine-fasting-accelerator Use code podcast to save 12% Link to full show notes and articles: https://bit.ly/3uKRKMC Connect with Dr. Ovadia: https://ifixhearts.com/quiz/ Show Notes: 0:00 Intro 1:30 Up to 95% of people with cardiac disease are insulin resistant. 4:45 Processed foods and high carbs are the two primary drivers of metabolic disease, the primary driver of heart disease. 6:53 Insulin resistance damages blood vessels. 11:18 Exercise is indirectly helpful in preventing atherosclerosis. 13:10 The better you can maintain muscle as you age, the better you can deal with the aging process. 14:30 It is possible to reverse atherosclerosis. 16:30 Tests: coronary artery calcium scan (CAC) and coronary CT angiogram (CCTA). 18:30 People in their 30s and 40s now end up on the cardiac operating table. 20:30 High LDL may not be dangerous in a person who is metabolically healthy. 21:00 The quality of your LDL particles is important. 22:54 90% of adults are metabolically unhealthy, so their high LDL is likely dangerous. 24:05 Statin use for over 10 years increases your risk of developing insulin resistance and type 2 diabetes, primary drivers of heart disease. 26:30 Inflammation is an important part of the development of heart disease. 27:40 High blood pressure root cause is insulin resistance/metabolic disease. 31:41 Ferritin testing measures total body iron stores. It is also an inflammation marker. 35:50 Linoleic acid LDL oxidation hypothesis 37:30 Plant-based diets 40:25 Lowering your intake of omega 6 improves your omega 3 index. 41:10 Low vitamin D 42:00 Sun exposure has been misunderstood. 44:10 Triglycerides is a higher risk than LDL. 48:30 Bioidentical hormones are superior to synthetic. 50:03 Low testosterone is a risk factor for heart disease. 53:10 Heart surgery does not fix the underlying problem.      

Nick Norwitz is an MD student at Harvard, & holds a PhD from Oxford in metabolism and nutrition. JOIN THE PATREON FAMILY: https://patreon.com/dannyjones SPONSORS https://ver.so/danny - Use code DANNY to save 15% on your first order. https://ketobrainz.com/pages/djp - Use code "DANNY20" at checkout. EPISODE LINKS https://www.youtube.com/@nicknorwitzPhD https://twitter.com/nicknorwitz FOLLOW DANNY JONES https://www.instagram.com/jonesdanny https://twitter.com/jonesdanny OUTLINE 00:00 - Nick's medical situation 07:02 - Ketogenic diet science 10:49 - Health industry contradictions 15:03 - Nutrition documentaries 20:12 - 500 LDL on low carb diet 23:41 - Lean mass hyper responder 34:43 - Evidence carbohydrates reduce cholesterol 36:50 - Oreo VS Statin Experiment 49:15 - Backlash from medical community 53:34 - Oreos vs Statin test results 01:11:03 - Adding carbs to Ketogenic diet 01:14:08 - Seed oils; polyunsaturated fats 01:16:02 - Risk profiles for heart disease 01:22:47 - Arterial plaque in fit people with high cholesterol 01:26:49 - ApoB & LP(a) 01:29:29 - Misconceptions about Keto 01:33:29 - Expanding the LMHR study 01:35:37 - Harvard Medical school 01:37:47 - Broken medical system 01:39:40 - Misinformation in medical journals 01:53:59 - GLP-1 fat loss meds 01:59:29 - Weight lifting affects on LDL 02:07:20 - Cardio effects on LDL 02:08:06 - Neuro-protective effects of Keto 02:10:53 - DARPA's interest in Keto diet 02:14:39 - Allulose: Healthy sugar? 02:21:17 - Diet Coke

Dr. Nicholas Norwitz obtained his Ph.D. in ketogenic nutrition and metabolism from Oxford University and is pursuing his MD at Harvard Medical School. He is a certified Metabolic Health Practitioner (MHP), and the author of peer-reviewed scientific papers and textbook chapters on topics including Alzheimer's disease, cardiovascular disease, diabetes, gastrointestinal health, genetics, osteology, and Parkinson's disease, as well as a blogger and lecturer on the application of the ketogenic diet as metabolic medicine. Follow and contact Dr Norwitz here: Twitter https://twitter.com/nicknorwitz YouTube www.youtube.com/@nicknorwitzPhD/videos Oreo cookies vs statin crossover experiment: https://www.mdpi.com/2218-1989/14/1/73 Oreos vs Statins discussion video: https://youtu.be/L1mMnnyJrgk?si=WfnE2aKxQhOnQW2y   Topics discussed:  -Lean Mass hyper responders data -Oreo Cookies vs Statins to lower LDL experiment -"You are what you eat" Netflix special -Plant Chompers and Walter Willet   Contact and Follow Dr Chaffee: ✅PATREON for early releases, bonus content, and weekly Zoom meetings https://www.patreon.com/AnthonyChaffeeMD ✅Sign up for our 30-day carnivore challenge and group here! https://www.howtocarnivore.com/ ✅INSTAGRAM: @anthonychaffeemd www.instagram.com/anthonychaffeemd/ ✅TWITTER: @Anthony_Chaffee ✅TIKTOK: @AnthonyChaffeeMD ✅Apple Podcast: The Plant Free MD https://podcasts.apple.com/au/podcast/the-plant-free-md-podcast/id1614546790 ✅Spotify: The Plant Free MD https://open.spotify.com/show/0WQtoPLuPMWWm3ZT3DYXzp?si=PPc2rXZzQXuzjIRK__SEZQ ✅To Sign up for a personal consultation with me, you can use my Calendly link below to schedule an appointment: ✅60 minute consultation https://calendly.com/anthonychaffeemd/60-minute-consultation ✅For collaborations, please email me at the below address. Please understand that I cannot give advice over email, but only in a consultation setting: AnthonyChaffee@gmail.com For more of my interviews and discussions, as well as other resources, go to my Linktree at: ✅ https://linktr.ee/DrChaffeeMD OR my website at: ✅ www.TheCarnivoreLife.com   Sponsors and Affiliates: ✅ Brand Ambassador for Stone and Spear tallow and soaps referral link https://www.stoneandspeartallow.com/?ref=gx0gql8b Discount Code "CHAFFEE" for 10% off ✅ Carnivore t-shirts from the Plant Free MD  www.plantfreetees.com ✅THE CARNIVORE BAR: Discount Code "Anthony" for 10% off all orders!   https://the-carnivore-bar.myshopify.com/?sca_ref=1743809.v3IrTuyDIi ✅Barbell Foods Biltong and Meat Sticks Use code AC10 for 10% of all orders! www.barbellfoods.com.au ✅Schwank Grill (Natural Gas or Propane) https://glnk.io/503n/anthonychaffeemd $150 OFF with Discount Code: ANTHONYMD ✅Butcher Crowd Meat Deliveries https://home.butchercrowd.com.au/?via=anthony Code CARNIVORE20 for $20 off your first purchase ✅ iRestore Laser Hair Therapy: $400 off with discount code AnthonyChaffee https://glnk.io/wyrl/anthonychaffee ✅X3 bar system with discount code "DRCHAFFEE" https://www.kqzyfj.com/click-100676052-13511487 ✅Cerule Stem cells https://DrChaffee.cerule.com ✅CARNIVORE CRISPS: Discount Code "DRCHAFFEEMD" for 10% off all orders! www.carnivorecrisps.com ✅Shop Amazon https://www.amazon.com/shop/anthonychaffeemd?ref=ac_inf_hm_vp   And please like and subscribe to my podcast here and Apple/Google podcasts, as well as my YouTube Channel to get updates on all new content, and please consider giving a 5-star rating as it really helps!   This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.  

Download the 9-Page "Cognitive Enhancement Blueprint" Discover my premium podcast The Aliquot Show notes are available by clicking here Peter Attia, MD is a highly respected expert in preventive medicine, focused on the crucial subject of longevity and cardiovascular health. He's also the author of the NY Times best selling book Outlive - which I highly recommend if you have not read it already. Peter's philosophy transcends the conventional goal of merely extending lifespan; it's about enriching the quality of every year, ensuring that each stage of life is lived with optimal health and vitality. In this episode, we discuss: (00:07:36) Defining cardiovascular disease (00:09:43) Coronary plaque and fatality risk (00:11:09) What is cholesterol? (00:13:34) How ApoB predicts heart disease (00:21:34) Factors elevating ApoB (00:25:24) ApoB reference range explained (00:27:23) Does high ApoB cause cardiovascular disease (00:37:01) ApoB thresholds for ASCVD prevention (00:40:27) Dietary factors raising ApoB (00:39:33) Genetics of ApoB and LDL (00:53:24) Does low LDL increase cancer? (00:56:19) Cholesterol-lowering drugs (00:59:59) Statins, uses, and side effects (01:03:12) Are statins toxic to mitochondria? (01:09:56) Ubiquinol for statin-induced muscle soreness (01:11:09) How to train in zone 2 (01:17:09) Statins and neurodegenerative disease risk (01:21:54) Cholesterol synthesis in the brain (desmosterol role) (01:25:58) Statin alternatives – pros and cons (01:27:30) Ezetimibe (01:31:01) Bempedoic acid (01:36:49) Berberine for CVD Risk Reduction? (01:39:36) Muscle as a glucose sink (01:45:58) Chronic glucose toxicity and vascular impact (01:51:38) Hemoglobin A1C Levels and Mortality Data (01:55:35) 80/20 Zone 2/VO2 Max Training Protocol (02:02:12) Insights from VO2 max testing data (02:12:17) How obesity increases cancer risk (02:15:03) Cancer screening benefits and risks (02:20:47) Dr. Attia's recommended cancer screening age (02:28:54) Liquid biopsies for detecting cancer (02:34:48) CT scans, mammograms and radiation concerns (02:40:32) Menopause – hormonal shifts and health effects (02:45:13) Hormone replacement therapy (HRT) (02:58:57) Perimenopause diagnosis with hormone levels (03:02:04) HRT's impact on dementia, cancer, and heart disease risk (03:04:49) Estrogen's role in bone density (03:07:42) Vitamin D (03:16:24) Testosterone replacement for women's sexual function (03:18:47) HRT safety 10 years post-menopause (03:23:05) Treating low testosterone in men (03:29:53) TRT side effects and risks (03:32:33) Ways to reduce blood pressure (03:39:33) How to measure blood pressure (03:45:30) Peter's longevity optimization routines Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/premium

Picture yourself in your mid-70s, feeling as though you're at the prime of your life.  Yes, it's possible. Meet Warren Matthews, a 76-year-old researcher, a pioneer in the field of natural health, and a living testament to the age-defying benefits of his work. Born in Christchurch, New Zealand, the son of a carpenter, Warren's path has been remarkable. For over 40 years, he's been a driven entrepreneur with a passion for technological innovation and environmental sustainability, successfully establishing multiple businesses along the way. Around two decades ago, Warren's unwavering interest in health and well-being led him to channel his energy and resources into the field of natural health. In 1998, he, alongside his son, Lance Matthews, embarked on a journey that would ultimately result in the creation of Xtend-Life Natural Products in 2000. Today, Xtend-Life is celebrated as one of New Zealand's business success stories, known for its commitment to purity, innovative formulations, and competitive pricing. Their products, ranging from natural supplements to Zupafoods™, Omega-3, and skincare, reach thousands of customers in over 40 countries each month. Warren's mission is clear: to promote scientific research and wider public awareness of the genuine benefits of pure, natural products combined with sensible diet and lifestyles. My second guest, Ivor Cummins, is a seasoned chemical engineer with a remarkable career in the medical device industry and beyond. With a specialty in leading teams through complex problem-solving efforts, Ivor's expertise is unquestionable. He's a University College Dublin graduate who spent the first six years of his career developing and optimizing medical devices like hemodialysis units, hemoperfusion cartridges, and coronary stent assemblies. Over the years, Ivor continued to enhance his professional knowledge by becoming a Chartered Engineer (CEng) and a Project Management Professional (PMP). He also completed an Innovation and Entrepreneurial Management Certificate at Stanford University. In today's episode, Warren will share his remarkable insights into living a long and healthy life at the age of 76, Ivor will explore the intricate world of multivitamin absorption and delivery mechanisms, and we'll unravel the significance of blending different forms of vitamins, minerals, and supplements for optimal health.  Full Show Notes: https://bengreenfieldlife.com/xtend Episode Sponsors: Neurohacker Qualia Synbiotic: Visit neurohacker.com/BGL15  to try Qualia Synbiotic risk-free for 100 days and code BGL15 at checkout for 15% off. Organifi (Gold Pumpkin): Visit organifi.com/Ben for 20% off your order. LMNT: Visit DrinkLMNT.com/BenGreenfield to get a free gift with your purchase! Brain.fm: Visit brain.fm/ben30 and get 30% off using the offer code BEN30. ProLon: Visit ProLonLife.com/BEN and save 15% on your order.See omnystudio.com/listener for privacy information.

Dr. Aseem Malhotra, MD, is an NHS Trained Consultant Cardiologist, and visiting Professor of Evidence-Based Medicine, Bahiana School of Medicine and Public Health, Salvador, Brazil. He is the author of several books, including "The Pioppi Diet", "The 21-day Immunity Plan", and "A Statin-free Life". www.doctoraseem.com