POPULARITY
Slovenija se stara hitro – in tega trenda ne bo mogoče ustaviti. Že skoraj pred 10imi leti je številčnost starostnikov 65+ preseglo število naše najmlajše populacije, stare do 18 let. Do sredine stoletja bo skoraj vsak tretji prebivalec Unije starejši od 65 let. Število starejših od 80 let pa se bo v tem času skoraj podvojilo. Hkrati bodo naraščali stroški pokojnin, zdravstva in dolgotrajne oskrbe, največji pritisk pri nas je pričakovati okoli leta 2060. Urška Valjavec se je o posledicah demografije pogovarjala z dr. Andražem Rangusom, raziskovalcem Inštituta za ekonomska raziskovanja. Prisluhnite jima v sredinem Intervjuju po deseti na Prvem.
En este episodio nos adentramos en una de las estructuras más fascinantes y peor simplificadas del sistema nervioso: el tálamo. Durante años se nos ha enseñado como una gran “estación de relevo sensitiva”, pero esa metáfora se queda corta. El tálamo no solo transmite información hacia la corteza: la filtra, la organiza, la modula y participa en el estado funcional en el que esa información llega al cerebro consciente. A lo largo del episodio recorremos su historia, su lugar dentro del diencéfalo, sus principales núcleos y su papel en sensibilidad, visión, audición, movimiento, memoria, atención, cognición y conciencia. Pero el episodio no se queda en la anatomía clásica. Entramos también en la neurofisiología moderna del tálamo: entradas drivers y modulators, núcleos de primer orden y de orden superior, bucles cortico-tálamo-corticales, modos de disparo tónico y en ráfaga. Finalmente, aterrizamos todo en clínica: ictus talámicos, dolor central, afasia talámica, negligencia, alteraciones cognitivas, trastornos del movimiento, arteria de Percheron, mesocircuito de Schiff y la idea central del episodio: el tálamo enferma como nodo, no como simple estación. Referencias del episodio: 1. Atallah, O., Almealawy, Y. F., Alabide, A. S., Farooq, M., Sanker, V., Alrubaye, S. N., Darwazeh, R., Awuah, W. A., Abdul-Rahman, T., Muthana, A., Saleh, A., Wellington, J., & Badary, A. (2024). Navigating the clinical landscape of artery of Percheron infarction: A systematic review. eNeurologicalSci, 37, 100521. https://doi.org/10.1016/j.ensci.2024.100521 (https://pubmed.ncbi.nlm.nih.gov/39257866/). 2. Biesbroek, J. M., Verhagen, M. G., van der Stigchel, S., & Biessels, G. J. (2024). When the central integrator disintegrates: A review of the role of the thalamus in cognition and dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association, 20(3), 2209–2222. https://doi.org/10.1002/alz.13563 (https://pmc.ncbi.nlm.nih.gov/articles/PMC10984498/). 3. Bolkan, S. S., Stujenske, J. M., Parnaudeau, S., Spellman, T. J., Rauffenbart, C., Abbas, A. I., Harris, A. Z., Gordon, J. A., & Kellendonk, C. (2017). Thalamic projections sustain prefrontal activity during working memory maintenance. Nature neuroscience, 20(7), 987–996. https://doi.org/10.1038/nn.4568 (https://pubmed.ncbi.nlm.nih.gov/28481349/). 4. Cacciatore, M., Magnani, F. G., Barbadoro, F., Ippoliti, C., Stanziano, M., Clementi, L., Nigri, A., Nanetti, L., Marino, S., La Porta, F., Lucca, L. F., Prada, F., & Leonardi, M. (2025). Thalamus and consciousness: a systematic review on thalamic nuclei associated with consciousness. Frontiers in neurology, 16, 1509668. https://doi.org/10.3389/fneur.2025.1509668 (https://pmc.ncbi.nlm.nih.gov/articles/PMC12241866/). 5. Cao, T., He, S., Wang, L., Chai, X., He, Q., Liu, D., Wang, D., Wang, N., He, J., Wang, S., Yang, Y., Zhao, J., & Tan, H. (2024). Clinical neuromodulatory effects of deep brain stimulation in disorder of consciousness: A literature review. CNS neuroscience & therapeutics, 30(6), e14559. https://doi.org/10.1111/cns.14559 (https://pubmed.ncbi.nlm.nih.gov/38115730/). 6. Fritsch, M., Rangus, I., & Nolte, C. H. (2022). Thalamic Aphasia: a Review. Current neurology and neuroscience reports, 22(12), 855–865. https://doi.org/10.1007/s11910-022-01242-2 (https://pmc.ncbi.nlm.nih.gov/articles/PMC9750901/). 7. Gupta, N., & Pandey, S. (2018). Post-Thalamic Stroke Movement Disorders: A Systematic Review. European neurology, 79(5-6), 303–314. https://doi.org/10.1159/000490070 (https://pubmed.ncbi.nlm.nih.gov/29870983/). 8. Marcuse, L. V., Langan, M., Hof, P. R., Panov, F., Saez, I., Jimenez-Shahed, J., Figee, M., Mayberg, H., Yoo, J. Y., Ghatan, S., Balchandani, P., & Fields, M. C. (2025). The thalamus: Structure, function, and neurotherapeutics. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 22(2), e00550. https://doi.org/10.1016/j.neurot.2025.e00550 (https://pubmed.ncbi.nlm.nih.gov/39956708/). 9. Mitchell A. S. (2015). The mediodorsal thalamus as a higher order thalamic relay nucleus important for learning and decision-making. Neuroscience and biobehavioral reviews, 54, 76–88. https://doi.org/10.1016/j.neubiorev.2015.03.001 (http://pubmed.ncbi.nlm.nih.gov/25757689/). 10. Schiff N. D. (2010). Recovery of consciousness after brain injury: a mesocircuit hypothesis. Trends in neurosciences, 33(1), 1–9. https://doi.org/10.1016/j.tins.2009.11.002 (https://pubmed.ncbi.nlm.nih.gov/19954851/). 11. Schmahmann J. D. (2003). Vascular syndromes of the thalamus. Stroke, 34(9), 2264–2278. https://doi.org/10.1161/01.STR.0000087786.38997.9E (https://pubmed.ncbi.nlm.nih.gov/12933968/). 12. Schmitt, L. I., Wimmer, R. D., Nakajima, M., Happ, M., Mofakham, S., & Halassa, M. M. (2017). Thalamic amplification of cortical connectivity sustains attentional control. Nature, 545(7653), 219–223. https://doi.org/10.1038/nature22073 (https://pubmed.ncbi.nlm.nih.gov/28467827/). 13. Sherman, S. M., & Guillery, R. W. (1998). On the actions that one nerve cell can have on another: distinguishing "drivers" from "modulators". Proceedings of the National Academy of Sciences of the United States of America, 95(12), 7121–7126. https://doi.org/10.1073/pnas.95.12.7121 (https://pubmed.ncbi.nlm.nih.gov/9618549/). 14. Sherman S. M. (2016). Thalamus plays a central role in ongoing cortical functioning. Nature neuroscience, 19(4), 533–541. https://doi.org/10.1038/nn.4269 (https://pubmed.ncbi.nlm.nih.gov/27021938/). 15. Steriade M. (2005). Sleep, epilepsy and thalamic reticular inhibitory neurons. Trends in neurosciences, 28(6), 317–324. https://doi.org/10.1016/j.tins.2005.03.007 (http://pubmed.ncbi.nlm.nih.gov/15927688/). 16. Whyte, C. J., Redinbaugh, M. J., Shine, J. M., & Saalmann, Y. B. (2024). Thalamic contributions to the state and contents of consciousness. Neuron, 112(10), 1611–1625. https://doi.org/10.1016/j.neuron.2024.04.019 (https://pubmed.ncbi.nlm.nih.gov/38754373/).
O ajdi smo se pogovarjali z Natašo in Antonom Rangus iz mlina Rangus. Predstavili smo zelo staro sorto ajde, ki ima odlične sestavine. Za produkt Tatarska ajdova kaša sta prejela tudi priznanje Inovacija desetletja.
O ajdi smo se pogovarjali z Natašo in Antonom Rangus iz mlina Rangus. Predstavili smo zelo staro sorto ajde, ki ima odlične sestavine. Za produkt Tatarska ajdova kaša sta prejela tudi priznanje Inovacija desetletja.
This new track was a ball buster all the way around. The guys rib me for buying a power tool item to clean my shower. Rangus the Prepper thinks I use to pee into and then we get into a … Continue reading →
This new show was definitely a ball buster! Rangus the Prepper was happy as anything that we were back in the Pit of Despair. CPAP Chuck mentions that coffee makes him poop and he had a 1 lbs poop! Ha! … Continue reading →
Another funny show in the list to listen to and share. We talk about a great new brownie place find then we get into several hilarious stories on a show Rangus the Prepper went to like the Ace Frehley concert. … Continue reading →
We have been gone for a mini bit but are right back on track. This latest show has Rangus the Prepper hacking his neighbor’s internet so he can Zoom in on the show! We then talk about me going to … Continue reading →
What a great new show! I talk about how I cut my lip on a fork and CPAP Chuck thinks it is because I use camping cookware from Goodwill. Ha! Rangus the Pampered Prepper has poor water pressure in his … Continue reading →
This new show begins on how I was doing some research and watching some porn and the craziest thing happened to my computer. Rangus the Prepper was able to help me out with how to fix it which is odd … Continue reading →
We are back and roaring with laughter as this new show begins. CPAP Chuck laughs at me for getting a used CPAP Machine from Rangus the Pampered Prepper! Ha! I talk about going back to work after my father’s funeral … Continue reading →
What a great new show this one is, starting with the cringing moment of Rangus the Pampered Bionic Prepper talking about his knee replacement. Then the laughter begins with A1 Wayne talking about going on a vacation golf trip in … Continue reading →
This latest show starts out hilariously as Rangus the Pampered Prepper is having technical difficulties with his video and it is funny as hell. Most of the time while we are talking to Gary he is making cocktails then we … Continue reading →
Always willing to lend a helping hand, our guest for Episode 112 of Black Flag Athletics Black Flag Radio is the Big Sexy himself, Chris Rangus. The life long tradesman lets us in on the values that he has learned and that have guided him to become a positive person. We also dive into the benefits of staying true to your passion, overcoming obstacles, evaluating progress, and how little acts of kindness have a much much larger impact. Enjoy!
This really funny show has us going in ten directions at one time with laughs. CPAP Chuck talks about IBS Ninjas, Rangus the Pampered Prepper wants a cook out, we think about using 23 & me, a conversation about Disney … Continue reading →
This show is another in a string of hilarious shows filled with bloopers and laughs. We start talking about a breather machine the CPAP Chuck had in his kitchen, then going into Halloween Peeps. Rangus the Prepper talks about people … Continue reading →
This new show, starts by saying how Rangus, Byron and Gary are absent for this latest but we move forward. A1 Wayne talks about how he loves PT Byron’s look, and how I went camping at our islands and how … Continue reading →
This returning show is a hilarious outburst show right after we turn on the mics. What a great new one , with Rangus the Pampered Prepper talking about his recent grilling experience and laughing about my Miley Cyrus grill. We … Continue reading →
This hilarious new show rolls out with A1 Wayne talking about Oxygen Bars, yes Oxygen bars. Rangus the Pampered Prepper then talks about his latest round of smoking meats, then we begin ribbing on Soundman Gary since he isn’t here … Continue reading →
This new show is a laughter fest from the start. Rangus the Pampered Prepper talks about his new smoker then we introduce our guest the great DJ Topgun. Don’t forget to follow him @djtopgun and mention you heard about him … Continue reading →
The crew enjoys some poorly-earned downtime. Dar explores the plumbing. Pleck reminisces about Rangus 6. C-53 can swim? Featuring: Jeremy Bent as C-53 Alden Ford as Pleck Decksetter Allie Kokesh as Dar Seth Lind as Nermut Bundaloy and Peck the Pervert Winston Noel as Sammo Moujan Zolfaghari as Bargie and Wink With special guest Lauren Adams as Bory Ampber Edited by Seth Lind Recorded at Braund Studios by Shane O’Connell Sound Design and Mix by Shane O’Connell Music by Brendan Ryan Additional music by Shane O’Connell Opening Crawl narration by Jeremy Crutchley Ship design for The Bargarean Jade by Eric Geusz