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View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Lisa Mosconi is a world-renowned neuroscientist and the director of the Women's Brain Initiative at Weill Cornell Medicine, where she studies how sex differences and hormonal transitions influence brain aging and Alzheimer's disease risk. In this episode, Lisa explores why Alzheimer's disease disproportionately affects women and why longer lifespan alone does not explain their nearly twofold risk compared to men. She explains why Alzheimer's disease may be best understood as a midlife disease for women, beginning decades before symptoms appear, and how menopause represents a fundamental brain event that reshapes brain energy use, structure, and immune signaling. The conversation also examines what advanced brain imaging reveals about preclinical Alzheimer's disease, estrogen receptors in the brain, and why genetic risks such as APOE4 appear to affect women differently from men. Finally, Lisa discusses the nuanced evidence around menopause hormone therapy, the legacy of the WHI, her new CARE Initiative to cut women's Alzheimer's risk in half by 2050, and practical, evidence-based strategies to support brain health through midlife—including lifestyle, sleep, metabolism, mood, and emerging therapies such as GLP-1 agonists and SERMs (selective estrogen receptor modulators). We discuss: How Lisa's personal family history and scientific background led her to focus on the intersection of women's health, brain aging, and Alzheimer's disease (AD) [2:45]; The long preclinical phase of AD and the emotional burden carried by patients before dementia becomes severe [7:15]; How AD compares to other common forms of dementia: prevalence, pathology, symptoms, diagnostic challenges, and more [10:45]; Why AD disproportionately affects women: how AD is not simply a disease of old age or longevity but a midlife disease in which women develop pathology earlier [16:15]; Menopause as a leading explanation for women's increased Alzheimer's risk, and how advanced braining imaging can detect early changes in the brain [26:15]; How a new method for imaging estrogen receptors in the brain is changing how we think about the menopause transition [35:45]; What estrogen receptor imaging can and cannot tell us about hormone therapy's potential impact on brain health [48:45]; Lisa's studies on the relationship between levels of systemic estrogen and density of estrogen receptors in the brain [58:00]; Why blood estrogen levels poorly reflect brain estrogen signaling, and how tightly regulated brain hormone dynamics complicate our understanding of menstrual-cycle and lifestyle effects [1:02:15]; The CARE Initiative: Lisa's research program looking to slash AD rates in women [1:07:45]; The dramatic difference in AD risk between men and women associated with APOE4 [1:10:45]; What the evidence suggests about menopausal hormone therapy (MHT) and AD risk, and why timing, formulation, and uterine status appear to matter [1:12:00]; How the CARE initiative plans to study MHT and AD risk, within the practical constraints of a three-year research window [1:17:30]; How to think about starting hormone therapy during perimenopause: balancing symptom relief, hormonal variability, and individualized care [1:21:00]; Investigating selective estrogen receptor modulators (SERMs) as a targeted approach to brain health during and after menopause [1:25:00]; Why estrogen became wrongly associated with cancer risk and what the evidence actually shows [1:29:30]; Why better biomarkers are central to advancing women's Alzheimer's research [1:38:30]; Modifiable risk factors for dementia, the limitations of risk models, and questionable conclusions drawn from observational data [1:44:15]; GLP-1 agonists and brain health: exploring potential neuroprotective effects of GLP-1 agonists beyond metabolic benefits [1:49:00]; The importance of lifestyle factors in reducing risk of dementia: practical strategies for women to support brain health [1:53:45]; Why long-term, consistent lifestyle habits are essential for building cognitive resilience and protecting brain health over decades [2:01:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
Brad and Jonathan continue unpacking *incremental gains* — the small, tactical decisions that compound into financial independence. This conversation moves quickly through **core FI math, expense optimization, retirement accounts, and tax strategy**, showing how flexibility, optionality, and understanding the rules of the game can radically change your long-term outcomes. Retirement Accounts: The Rules That Matter 401(k): Always Take the Match Employer match = free money Declining it = turning down part of your salary Pre-Tax Accounts Are Often Better for FI Account Benefit Traditional 401(k) Lowers taxable income today Traditional IRA Tax deduction now 457(b) Penalty-free access after separation
We have a classic episode for you. Master male hypogonadism diagnosis and management. Discover when and how to test, how to tackle confounding conditions, and why lifestyle changes may be more effective than testosterone therapy in certain patients. We are joined by Dr. Brad Anawalt, an expert in endocrine care, to guide us through the essentials.Claim CME for this episode at curbsiders.vcuhealth.org!Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CMEShow Segments Intro Case 1 History and Physical Laboratory Testing Effect of Lifestyle on Testosterone Case 2 Prostate and Cardiovascular risk Treatment Options and Considerations Secondary Causes of Hypogonadism Case 3 Testicular Size and Klinefelter Syndrome hCG and Clomiphene Monitoring and Follow-Up Take-Home Points Outro Credits Written and produced by Paul Wurtz MD. Show notes, cover art, and infographic also created by Paul Wurtz MD. Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP Reviewer: Sai S Achi MD, MBA, FACP Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Bradley D. Anawalt MD Sponsor: GustoTry Gusto today at gusto.com/CURB, and get three months free when you run your first payroll.Sponsor: LocumstoryLocumstory.com is literally just a free, unbiased resource dedicated to educating physicians about locums. Sponsor: MedStudy PodcastCurbsiders listeners get 15% off with code CURB15 at medstudy.comSponsor: The Sanford GuideCurbsiders listeners can get 20% off the already very moderately priced yearly subscriptions directly at sanfordguide.com. Go to sanfordguide.com and use the code, CURB at checkout.
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In today's episode, Tim Whitaker speaks with Pastor Kimberly Bulgin who shares her transformative journey from traditional ministry to empowering women to break free from patriarchy, sexual shame, and church abuse. She discusses her mission to help women reclaim their faith and navigate their relationships with God and themselves in a healthy, joyful way. Kim's Facebook Page Chapters 01:39 Pastor Kim's Journey: From Music Teacher to Senior Pastor 07:42 Transitioning from Traditional Ministry to Empowering Women 11:35 Reclaiming Faith: Navigating Church Hurt and Patriarchy 26:09 Navigating Sexual Ethics: From Purity Culture to Healthy Relationships 37:16 The Sisters Stay Dropping Gems: A New Perspective on Women in the Bible ____________________________________________________ TNE Podcast hosts thought-provoking conversations at the intersection of faith, politics, and justice. We're part of the New Evangelical's 501c3 nonprofit that rejects Christian Nationalism and builds a better path forward, rooted in Jesus and centered on justice. If you'd like to support our work or get involved, visit our website: www.thenewevangelicals.com Follow Us On Instagram @thenewevangelicals Subscribe On YouTube @thenewevangelicals This show is produced by Josh Gilbert Media | Joshgilbertmedia.com Learn more about your ad choices. Visit megaphone.fm/adchoices
Learn more about Tina at: https://www.propelmodels.comhttps://www.instagram.com/propelmodels/?next=%2F Show Notes:
Your gut already has its own version of Ozempic, and it's been doing this job long before injections existed.In this video, I explain how appetite is actually regulated, why synthetic shortcuts often create new problems over time, and what has quietly shut down the body's natural satiety signals for so many people.Once you understand the pathway drugs are trying to imitate, the question stops being “how do I eat less?” and becomes “why was my body blocked from doing this in the first place?”This is about restoring a system, not overpowering it.Chapters0:00 - Introduction: Your Body's Natural Ozempic0:53 - Hunger Is a Hormone Problem5:08 - How to Fix Your Hormone Signals7:28 - Why Ozempic Often Backfires10:54 - The Resistant Starch Solution15:03 - How to Use Resistant Starch18:12 - Rebuilding Your Gut Environment19:31 - Lifestyle Support for Gut HealthResources: • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: Instagram: https://www.instagram.com/TheHumanUpgradePodcast/ Facebook: https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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My name is Roxi Ruiz, and I am from McAllen, TX, which is located right on the Mexican/US border. My city has been voted the most obese city for 8 years in a row. I am the Mom of one amazing daughter. I am a Speech LanguageA pathologist who specialises in feeding disorders. I became an Intermittent Fasting in February of 2019 after being diagnosed with prediabetes and NAFLD. Both sides of my family have generational metabolic disorders. I found myself fasting after a coworker asked me to read Delay, Don't Deny by Gin Stephens to get my opinion on fasting. I had never heard of IF before this. I started my first fast that evening. I have lost and maintained a 30-pound weight loss over7 years, but more importantly, I have reversed my prediabetes and no longer have a fatty liver. I am one of two administrators for Gin Stephens's Community. Weare an online fasting community that is found on Facebook. When I am not working, I spend my time creating content for my Instagram and TikTok accounts. Feel free to find me @fastingrox In this update, we catch up with Roxi, who is about to celebrate seven years of living an IF lifestyle. Roxi delves into all things IF, and her insights are fantastic as always.Graeme's Links to connect with me directly. Come and Join Our Patreon Community At the Link Belowwww.patreon.com/thefastinghighway.Come for a month or stay for a year, check it out, and get all the content. Your first step to excellent support and accountability is right here. Make 2026 your year. To Book a Zoom Call With Graeme One-on-One, Go Here www.thefastinghighway.com Get help, get coaching.To Read My Book The Fasting Highway Amazon or all good book sellers.To Listen to My Audio Book Apple Books or many Audio Book Platforms Free on Joining The Patreon Community To be a guest on the show, please go to www.thefastinghighway.com, click on listen to the podcast, " and follow the how to be a guest prompt.Disclaimer - All views are those of the host and guest and should not be taken as medical advice. Please consult your doctor before starting any health plan.
"If you want answers, they are out there. But the one thing that I have learned is who do you have a testimony in? If you have a testimony in the church, if you have a testimony in the missionaries, in anything other than Jesus, it's going to fail you and you're going to fall. But if you have a testimony in Jesus and you really do believe that this is His church, all of those things-they'll pale. And when it's time for you to find those answers, you will find those answers. God works that way, line upon line, precept upon precept."00:00 Introduction and Personal Beliefs01:42 Welcoming Chase to the Podcast11:29 Post-Mission Life and Rebellion14:27 Life in the Mountains and Personal Realizations22:17 The Miracle and Reconnecting with Faith25:26 The Experiment Begins34:06 Struggles and Realizations40:22 Understanding Celestial ThinkingMemor Jewelry code COMEBACK for 10% offhttps://memorjewelry.com/Serve Clothing code COMEBACK for 15% offhttps://serveclothing.com/If you have a story to share please contact ashly.comebackpodcast@gmail.comFor inquiries contact info.comebackpodcast@gmail.comCome Back Team:Director, Founder, & Host: Ashly StoneEditor: Cara ReedOutreach Manager: Jenna CarlsonAssistant Editor: Michelle BergerAssistant Editor: Britt SmallzeArt Director: Jeremy GarciaProduction Director: Trent Wardwell
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Dave Watumull is on a mission to bring astaxanthin to the world. This marine super nutrient supports whole body health and longevity and has captured his imagination for more than 25 years of research, development, and commercialization. He is the Co-Founder and CEO of AX3 Life, a consumer health company dedicated to astaxanthin products, education, and community. He is also the COO of Cardax, a life sciences business focused on pharmaceutical and nutraceutical applications of astaxanthin. Today on the show we discuss: Why diet sleep and movement remain the foundation of longevity no matter what you supplement, how most longevity supplements collapse when you actually examine the science, the most overlooked longevity supplement that actually works, why hype and marketing dominate the biohacking space more than evidence, how astaxanthin works at the cellular level to support aging pathways and how to evaluate supplements intelligently without wasting money or chasing trends and much more. Get 20% off your first order of Ax3: https://ax3.life and use code "Doug" at checkout ⚠ WELLNESS DISCLAIMER ⚠ Please be advised; the topics related to health and mental health in my content are for informational, discussion, and entertainment purposes only. The content is not intended to be a substitute for professional advice, diagnosis, or treatment. Always seek the advice of your health or mental health professional or other qualified health provider with any questions you may have regarding your current condition. Never disregard professional advice or delay in seeking it because of something you have heard from your favorite creator, on social media, or shared within content you've consumed. If you are in crisis or you think you may have an emergency, call your doctor or 911 immediately. If you do not have a health professional who is able to assist you, use these resources to find help: Emergency Medical Services—911 If the situation is potentially life-threatening, get immediate emergency assistance by calling 911, available 24 hours a day. National Suicide Prevention Lifeline, 1-800-273-TALK (8255) or https://suicidepreventionlifeline.org. SAMHSA addiction and mental health treatment Referral Helpline, 1-877-SAMHSA7 (1-877-726-4727) and https://www.samhsa.gov Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode, I sit down with Laurie Hammer, a functional nutrition therapist, to explore the powerful connection between brain health and gut function. Laurie shares her personal journey into functional nutrition and explains why amino acids play a foundational role in both emotional resilience and physical well-being. Our conversation dives into the relationship between neurotransmitters and amino acids, with a focus on serotonin, GABA, and catecholamines. Laurie explains how imbalances in these systems can contribute to anxiety, depression, and even neurodegenerative conditions. Through clinical experience and real-world examples, she outlines how targeted amino acid therapy can create meaningful changes when applied thoughtfully and individually. We also expand the discussion beyond supplementation to the lifestyle factors that support optimal brain health. From adequate protein intake and environmental toxin reduction to grounding practices and cleaner personal care products, this episode offers a holistic framework for supporting the nervous system. It is an insightful conversation for anyone interested in practical, nutrition-driven strategies to improve brain health and long-term vitality. Key takeaways: Amino acids are crucial for neurotransmitter balance, impacting mental health and overall well-being. Laurie Hammer emphasizes the therapeutic potential of tryptophan, glutamine, and the role of other essential amino acids in addressing brain and gut health. Lifestyle changes, including nutrient-rich diets, sunlight exposure, and grounding, are essential for maintaining optimal neurological health. Targeted, therapeutic supplementation of amino acids can significantly improve symptoms of anxiety and depression by nourishing the nervous system. Laurie Hammer's approach encourages tackling brain health through foundational elements like proteins, fats, and minerals, rather than solely focusing on genetic predispositions. More About Laurie Hammer: Laurie Hammer is a Functional Nutritional Therapist, speaker, and host of the Take Back My Brain Podcast. She specializes in targeted amino acid therapy and brain-first nutrition to help women—and the practitioners who serve them—overcome anxiety, overwhelm, brain fog, and burnout without relying on medications. Laurie is the creator of the Mind Thrive Amino Acid Therapy Certification and is known for her bold message: You can't medicate away a nutrient deficiency. Website Instagram Facebook Connect with me! Website Instagram Facebook YouTube
Part 2: Dr. Phil sits down with Roshin and Tyler, whose extraordinary true story has captivated millions online. At just 13 years old, Roshin fled an abusive home to survive. Unbeknownst to her, a police officer named Tyler was part of the search team that night. Fifteen years later, they reconnected while working together at the sheriff's department, fell in love, and got engaged. In this powerful episode, they reveal the harrowing details of Roshin's escape, her struggles in foster care, and the incredible twist of fate that brought them together, proving that hope and healing are possible even after the darkest chapters.Thank you to our sponsors:NMLS 182334, https://nmlsconsumeraccess.org APR for rates in the 5s start at 6.196% for well qualified borrowers. Call 888-841-1319, for details about credit costs and terms. Or https://americanfinancing.net/PhilChapter: Don't wait! If you're on Medicare or will be soon, reach out to Chapter. Call: (352)-845-0659 or go to https://askchapter.org/ to learn about your Medicare options and get help finding ways to save money.Watch Dr. Phil on Linear (Subscriptions needed):Spectrum/Charter - https://www.spectrum.com/cable-tv/channel-lineup (Search for Envoy TV; Channel may vary by location)Frndly TV - https://watch.frndlytv.com/channel/live/envoy_tvFAST (No subscriptions needed):SamsungTV Plus - Channel 2977 or found in the category Lifestyle & Pop CultureLocal Now - Download the app on your CTV or stream via Web https://localnow.com/channels/envoy-fastVIDAA on Hisense TV's:Watch on Hisense TV's with VIDAA OS or download the VIDAA App:IOS: https://apps.apple.com/gb/app/vidaa/id1526408639Google Play: https://play.google.com/store/apps/details?id=com.universal.remote.multi&hl=en_USSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Ep 730: Ethical Broads PRIVATEWe kick off FOLLOW UP with California's AG sending a cease-and-desist to xAI over Grok generating creepy deepfakes of minors, while regulators finally notice Elon Musk's xAI datacenter illegally running methane turbines in Memphis. The FTC is also appealing its loss in the Meta monopoly case, because apparently breaking up Zuckerberg's data empire is still the hill they want to die on.IN THE NEWS, Washington joins the age-verification-for-porn parade, the UK considers an Australia-style social media ban for kids under 16, and governments everywhere continue demanding your ID before you're allowed to enjoy the internet. OpenAI rolls out age prediction for ChatGPT accounts ahead of a rumored adult mode—though hey, at least you can now group tabs in ChatGPT's Atlas browser. Anthropic rewrites Claude's “constitution” to make it more vibes-based, Nevada moves to block Polymarket because gambling is only legal when the house owns the house, and YouTube promises even more AI features in 2026. Elsewhere, a Swiss suicide pod gets an AI “mental fitness” upgrade, Microsoft's CEO begs AI developers to do something useful before the grid collapses, Musk hunts for a $134 billion payday from OpenAI and Microsoft, and makes yet more Davos predictions about robotaxis and aliens that are absolutely happening this year. On the bright side, A-list creatives push back on AI and Comic-Con bans AI art, buying humans a little more time.MEDIA CANDY finds us slogging through Wish, The Pitt, and the “Mel's Diner in Space” look of Star Trek: Starfleet Academy. We confirm 20-year-old CGI wargs still look terrible, get cautiously excited for 28 Years Later: The Bone Temple, and note that Fallout Season 2's weekly drops may not be working for a binge-rotted audience.In APPS & DOODADS, X launches Bluesky-style starter packs—presumably to help you find more Nazis—while ICE becomes one of the most-blocked accounts on Bluesky. Threads edges out X in daily mobile users, proving the “federated future” is just another Zuck app. And yes, we think we know what the Apple AI pin is—and definitely what it isn't.AT THE LIBRARY, we check out The Elements, Jet Tila's 101 Thai Dishes You Need to Cook Before You Die, Half Baked Harvest: Quick & Cozy, and Southern Living's A Southern Gentleman's Kitchen. Scott reports back from a Jim Butcher talk, where we learn Harry Dresden sounds suspiciously like Han Solo.We close with THE DARK SIDE WITH DAVE, who is juggling five podcasts while reading Going to the Top: The Story of Videopolis, plus teasers for Star Wars: Maul – Shadow Lord and a baffling Masters of the Universe trailer, a rant on what “remastered” even means anymore, a dishwasher follow-up, and the grim news that a lot of snow is coming.Sponsors:DeleteMe - Get 20% off your DeleteMe plan when you go to JoinDeleteMe.com/GOG and use promo code GOG at checkout.SquareSpace - go to squarespace.com/GRUMPY for a free trial. And when you're ready to launch, use code GRUMPY to save 10% off your first purchase of a website or domain.Private Internet Access - Go to GOG.Show/vpn and sign up today. For a limited time only, you can get OUR favorite VPN for as little as $2.03 a month.SetApp - With a single monthly subscription you get 240+ apps for your Mac. Go to SetApp and get started today!!!1Password - Get a great deal on the only password manager recommended by Grumpy Old Geeks! gog.show/1passwordShow notes at https://gog.show/730Watch on YouTube at https://youtu.be/LiwVkLKr8CoFOLLOW UPCalifornia AG sends cease and desist to xAI over Grok's explicit deepfakesElon Musk's xAI datacenter generating extra electricity illegally, regulator rulesZuck stuck on Trump's bad side: FTC appeals loss in Meta monopoly caseIN THE NEWSWashington is the latest state pursuing an age verification law for porn sitesThe UK is mulling an Australia-like social media ban for users under 16OpenAI is launching age prediction for ChatGPT accountsYou can now group tabs on OpenAI's ChatGPT Atlas browserAnthropic Updates Claude's 'Constitution,' Just in Case Chatbot Has a ConsciousnessNevada files to block Polymarket from offering ‘unlicensed wagering' in the stateYouTube CEO promises more AI features in 2026Controversial Swiss Suicide Pod Gets an AI-Powered Mental Fitness UpgradeMicrosoft CEO urges AI developers 'to get to a point where we are using this to do something useful,' or 'lose even the social permission...to generate these tokens'Elon Musk is looking for a $134 billion payout from OpenAI and MicrosoftElon Musk Sure Made Lots of Predictions at DavosA-List creatives sign up to fight AI, say it enables 'theft at a grand scale'Comic-Con Bans AI Art After Artist PushbackMEDIA CANDYWishThe PittStar Trek: Starfleet Academy28 Years Later: The Bone Temple'Fallout' Season 2's Weekly Drops May Not Be WorkingAPPS & DOODADSX is also launching Bluesky-like starter packsICE becomes one of the most-blocked accounts on Bluesky after its verificationThreads edges out X in daily mobile users, new data showsI think I know what the Apple pin is, and definitely know what it isn'tApple Developing AirTag-Sized AI Pin With Dual CamerasNot to be outdone by OpenAI, Apple is reportedly developing an AI wearableSiri's iOS 27 upgrade sounds exactly right. Apple's AI pin sounds exactly wrongAT THE LIBRARYThe Elements by John Boyne101 Thai Dishes You Need to Cook Before You Die by Jet TilaHalf Baked Harvest Quick & Cozy: A Cookbook by Tieghan GerardPestleSouthern Living A Southern Gentleman's Kitchen: Adventures in Cooking, Eating, and Living in the New South by Matt MooreTHE DARK SIDE WITH DAVEDave BittnerThe CyberWireHacking HumansCaveatControl LoopOnly Malware in the BuildingGoing to the Top: The Story of Videopolis—Part OneStar Wars: Maul - Shadow Lord | Official Teaser Trailer | Streaming April 6 on Disney+Masters of The Universe – Official Teaser TrailerCLOSING SHOUT-OUTSClassic-Era Scorpions Bassist Francis Buchholz Dies at 71See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
This episode covers: • Real Food Reset in U.S. Dietary Policy The new Dietary Guidelines for Americans 2025–2030 put real food back at the center of U.S. nutrition policy and take a direct swing at ultra processed foods, added sugar, and sugary drinks. Dave breaks down why this matters beyond personal dieting: these guidelines influence school meals, SNAP and WIC, federal feeding programs, and they shape what eventually shows up on labels and in public institutions. He also shares how biohackers can use this shift as leverage to push for better food environments in schools, workplaces, and hospitals. -Source: https://www.usda.gov/about-usda/news/press-releases/2026/01/07/kennedy-rollins-unveil-historic-reset-us-nutrition-policy-put-real-food-back-center-health • Drug Combo Extends Lifespan of Frail Old Mice by 73% A new aging study found that combining oxytocin with a compound called A5i extended the remaining lifespan of frail elderly male mice by 73%, while also improving function and tissue health. Dave explains why this is a big signal for the future of longevity medicine: stacking targeted interventions can outperform single compounds, especially when you start late in life. He also explains what to do with the idea right now: stop building random “everything stacks” and start thinking in phases, tracking outcomes, and waiting for real human combo data. -Source: https://www.futura-sciences.com/en/study-finds-drug-combo-could-slow-aging-and-increase-lifespan-by-73_23229/ • ChatGPT Health Turns Your Data Into a Health OS OpenAI launched ChatGPT Health, a dedicated health experience that lets you securely connect medical records and wellness apps like Apple Health and MyFitnessPal, so you can summarize visits, interpret labs, and prepare better questions for your doctor. Dave explains why this is a turning point for quantified self and protocol building: it reduces the friction of pulling data from five different places, and it makes pattern-finding accessible to nontechnical people. He also shares how to use it like a pro: clean inputs, smarter questions, and better doctor conversations. -Source: https://openai.com/index/introducing-chatgpt-health/ • Whole Milk Is Back in Schools The Whole Milk for Healthy Kids Act restores whole and reduced-fat milk options in schools, aligning school nutrition rules with the updated dietary guidelines that no longer treat full-fat dairy like a default villain. Dave breaks down why this matters for child healthspan: satiety and nutrient density drive behavior, learning, and metabolic stability. He also explains why this is a real-world policy experiment worth watching across school districts, and how it can open the door for bigger institutional upgrades like better protein and fewer ultra processed items. -Source: https://www.usda.gov/about-usda/news/press-releases/2026/01/14/whole-milk-back-president-trump-signs-whole-milk-healthy-kids-act • Tirzepatide Trial Targets Biological Age With Aging Clocks A registered clinical trial titled Tirzepatide to Slow Biological Aging is using multiple DNA methylation aging clocks as primary endpoints, along with functional metrics like grip strength and a 6-minute walk test. Dave explains why this is a big maturity step for longevity science: instead of assuming metabolic improvement equals slower aging, this study is measuring biological age directly, across multiple clocks, with performance outcomes. He also shares the practical lesson for biohackers: stop relying on one favorite metric and start thinking in panels, function, and durability of results. -Source: https://clinicaltrials.gov/study/NCT07220473 All source links provided for direct access to the original research and reporting. This episode is designed for biohackers, longevity seekers, and high-performance listeners who want practical strategies rooted in cutting-edge science. Host Dave Asprey translates emerging research into actionable upgrades for your biology, from metabolism and food policy to AI-driven tracking, institutional nutrition, and biological aging measurement. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: Dietary Guidelines for Americans 2025-2030, real food policy reset, ultra processed foods policy, added sugar limits, sugary drinks guidelines, school lunch nutrition policy, SNAP WIC nutrition impact, USDA HHS dietary guidelines 2026, whole food protein guidelines, full fat dairy guidelines, oxytocin aging study, A5i lifespan extension, frail elderly mice lifespan 73 percent, combination longevity therapies, aging intervention synergy, staged longevity protocols, functional aging biomarkers, ChatGPT Health launch, OpenAI health records AI, Apple Health ChatGPT integration, MyFitnessPal ChatGPT integration, AI lab interpretation, AI doctor visit summary, quantified self AI tools, Whole Milk for Healthy Kids Act, whole milk back in schools, school dairy policy change, child satiety nutrition, school meal regulations USDA, tirzepatide biological aging trial, GLP-1 GIP longevity, epigenetic aging clocks trial, DNAmAge PhenoAge GrimAge DunedinPACE, grip strength aging endpoint, 6 minute walk aging endpoint, biological age measurement, longevity clinical trial endpoints, biohacking news update, longevity policy shifts, metabolic health upgrades Thank you to our sponsors! -BEYOND Conference 2026 | Register now at https://beyondconference.com/ -EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps:0:00 - Intro0:19 - New Dietary Guidelines2:09 - Longevity Research Breakthrough3:41 - ChatGPT Health Launch5:10 - Whole Milk Returns to Schools6:29 - GLP-1 Aging Trial7:34 - Weekly Upgrade Protocol9:09 - OutroSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this wide-ranging and deeply grounded conversation, Darin sits down with Dr. Richard J. Brown to unpack some of the most pressing issues at the intersection of modern medicine, aesthetics, ethics, lifestyle, and personal responsibility. From GLP-1 medications and obesity treatment to body dysmorphia, medical ethics, AI in healthcare, and the urgent need to integrate lifestyle medicine into traditional care, this episode explores what it truly means to help people heal — not just shrink symptoms. Dr. Brown shares candid insights from the front lines of plastic surgery, preventative medicine, and fatherhood, offering a rare look at how discipline, community, and generational health can reshape both individuals and the healthcare system itself. What You'll Learn The real role of GLP-1 medications in obesity treatment Why lifestyle change determines long-term success after weight loss drugs The ethical dangers of cosmetic medicine driven by profit and aesthetics How body dysmorphia is being amplified by social media culture Why some patients should be turned away from surgery The importance of mental health screening in aesthetic medicine How AI is reshaping medical research and clinical decision-making The risks of unverified online medical advice Why doctors receive almost no training in nutrition and exercise The disconnect between lifestyle medicine and the healthcare system How preventative medicine could radically reduce chronic disease The role of discipline, habit-building, and accountability in health Why community is one of the most powerful drivers of lasting change How generational health starts with parents modeling behavior Why personal responsibility is the foundation of true sovereignty Chapters 00:00:00 – Welcome to SuperLife and the mission of sovereignty 00:00:32 – Sponsor: TheraSage and frequency-based healing technologies 00:02:15 – Welcoming Dr. Richard J. Brown 00:02:55 – GLP-1 medications, obesity, and long-term use 00:03:31 – Why some people regain weight after stopping GLP-1s 00:04:20 – Lifestyle change as the differentiating factor 00:05:16 – Ethical concerns around GLP-1 misuse 00:06:02 – Body dysmorphia vs medical necessity 00:06:57 – GLP-1s as central nervous system drugs 00:07:37 – Compounding pharmacies and prescription risks 00:08:43 – Aesthetic pressure and social media distortion 00:09:31 – Ethics in plastic surgery and patient selection 00:10:05 – Saying no: turning patients away 00:11:19 – Weight loss, identity, and fear of letting go 00:12:20 – The need for qualified, ethical providers 00:13:13 – Exit strategies and long-term planning 00:14:22 – AI, ChatGPT, and medical misinformation 00:15:04 – How physicians are using AI responsibly 00:16:13 – Risks of self-diagnosis without medical context 00:17:17 – Empowered patients and the "Google MD" era 00:18:43 – Lifestyle medicine vs allopathic medicine 00:23:07 – Why lifestyle still isn't embraced by healthcare 00:24:21 – Doctors as educators, not just specialists 00:25:32 – The absence of nutrition training in medical school 00:27:17 – Redesigning medical education from the ground up 00:28:21 – Teaching exercise, VO₂ max, and resistance training 00:29:19 – How misinformation spreads through bad science 00:30:37 – Authority, algorithms, and ethical responsibility 00:32:12 – Debunking viral health claims 00:36:57 – Preventative medicine and generational health 00:38:26 – Parenting, discipline, and modeling health 00:39:35 – The 75 Hard program and mental resilience 00:42:15 – Planning, time management, and habit stacking 00:43:51 – Personal excellence as rebellion 00:45:25 – Health as agency and probability 00:47:22 – Community as the missing link 00:50:21 – A personal story on health consequences 00:52:03 – Accountability groups and shared momentum 00:54:12 – The future of plastic surgery and wellness integration 00:56:10 – Persistence, setbacks, and commitment 00:57:16 – Closing reflections and gratitude Thank You to Our Sponsors Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Our Place: Toxic-free, durable cookware that supports healthy cooking. Use code DARIN for 10% off at fromourplace.com. Manna Vitality: Go to mannavitality.com/ and use code DARIN12 for 12% off your order. Find More From Dr. Ricky: Instagram: @drrichardjbrown Website: drrichardjbrown.com YouTube: Dr. Ricky's YouTube Book: The Real Beauty Bible Find More From Darin: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Key Takeaway True medicine doesn't just change bodies — it changes behavior, belief systems, and the trajectory of future generations.
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Kat Braden built a massive online audience the hard way: consistency, work ethic, and a willingness to look cringe early.In this episode, we talk about how she went all-in on content (4 to 6 posts a day), what her real process looks like behind a 45-second video, why chasing views can burn you out, and how she's shifting toward creating content that actually adds value.We also get into boundaries, real-life connection vs social media, and how to use AI without letting it kill your creativity.Follow Kat here:Instagram: https://www.instagram.com/girlandadoodle/TikTok: https://www.tiktok.com/@girlandadoodleYouTube: https://www.youtube.com/@girlandadoodle
TODAY checks in with eager football fans in Seattle, Los Angeles, Denver, and Boston, ahead of this weekend's NFL conference championship games. Plus, Savannah Guthrie shares an inside look into her vocal cord surgery, her recovery, and rediscovering her voice. And Siri Daly whips up two soup recipes that you can make in bulk and freeze for later. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Today, I'm joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators. Use code NAT10 for 10% off products at https://alchemiqlabs.com/ Episode Timestamps: Welcome and episode introduction ... 00:00:00 Anthony Castore's path from strength coaching to cellular medicine ... 00:05:55 Connecting strength training with cellular pathways (AMPK, mTOR) ... 00:12:27 Explaining and balancing AMPK and mTOR for performance ... 00:13:03 Training strategies: Metabolic, hypertrophy, and neural approaches ... 00:18:18 Building a solid foundation: Lifestyle, training, nutrition, peptides ... 00:23:04 Assessing recovery capacity and individualizing protocols ... 00:26:02 Mitochondrial fission, fusion, and targeted adaptation ... 00:29:57 Optimizing muscle gain and fat loss through calories and recovery ... 00:31:00 Differentiating bodybuilder vs. longevity approaches ... 00:34:44 Integrating peptides and support molecules into routines ... 00:40:44 Ketone esters and mitochondrial peptide interventions ... 00:41:20 Cautions on stacking and combining interventions ... 00:54:04 Lessons learned from overdoing interventions ... 01:05:02 Our Amazing Sponsors: Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off. BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement — and get 20% off at beamminerals.com with code NAT20. Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
This week on STICK TO WRESTLING, we dive deep into Mid-South Wrestling from January 1986, a month where the booking fires on all cylinders. On the table this week: –The booking is fantastic. For example, Dick Slater is positioned perfectly as the wily veteran, using every trick in the book to outsmart a younger, less … Continue reading Episode 397: My Habits and My Lifestyle → The post Episode 397: My Habits and My Lifestyle appeared first on Stick To Wrestling with John McAdam.
Somewhere between those two truths is where football card collecting lives.This episode moves through the chaos of championship football and the chaos of the hobby. Big moments. Bigger emotions. We talk about hype cycles in real time. How collectors react when prices move fast. Why some cards feel right even when the data feels wrong.From modern quarterbacks carrying the future of the market to forgotten defenders with stories that never leaveThis is a conversation about how collectors think when the season is ending and the pressure is rising.If you collect football cards with your head and your heart this episode speaks your language.Check out Card Ladder the official data partner of Stacking SlabsFollow The Football Card Podcast on Instagram for memes and stuff.Get your free copy of Collecting For Keeps: Finding Meaning In A Hobby Built On HypeGet exclusive content, promote your cards, and connect with other collectors who listen to the pod today by joining the Patreon: Join Stacking Slabs Podcast Patreon[Distributed on Sunday] Sign up for the Stacking Slabs Weekly Rip Newsletter using this linkFollow Stacking Slabs: | Twitter | Instagram | Facebook | TiktokFollow Pack: | Instagram ★ Support this podcast on Patreon ★
This episode dives into the story of Cody Pritchett and his journey through business, marriage, and faith. Cody shares honest perspectives from the lessons learned along the way and the experiences that shaped who he is today. A real conversation you won't want to miss.
"The repair mechanisms don't work as well as you get older... The whole idea was: if we can give you more of the 'repair guys,' maybe we can reverse disease."Dr. Adeel Khan is a global thought leader in regenerative medicine. He is the CEO and Founder of and founder of Eterna Health, whose work with MUSE cell therapy—developed in collaboration with its discoverer, Professor Mari Dezawa—has made him the go-to expert for world leaders, athletes, and celebrities Chris Hemsworth, Kim Kardashian, and Tony Robbins. In this episode, we move beyond the hype of "anti-aging" to explore the hard science of Muse cells (Multilineage-differentiating Stress-Enduring cells). Dr. Khan breaks down how these unique cells differ from the "medicinal signaling cells" (MSCs) found in most clinics and how they act as a bridge to a future where tissue regeneration is standard care.(0:00) The Future of Regenerative Medicine(6:13) The Muse Difference: Why these cells are "pluripotent" (able to become any tissue) without the cancer risks of Yamanaka factors.(10:29) Curing the Incurable: Diabetes & Alzheimer's (11:27) The Cure Triad: How combining stem cells, gene therapy, and Fecal Microbial Transplants (FMT) could cure complex autoimmune diseases within a decade.(12:56) Biological Noise: Measuring the "mistakes" in our gene expression to quantify aging.(16:42) Lifestyle as Medicine: Why Dr. Khan prescribes community, mindfulness, and nature immersion alongside advanced therapies.(18:13) From Sketchy to Standardized: The Regulatory Landscape(23:25) A Personal Mission: Trying to Save Mom(25:38) The Cancer Hunter: How Muse cells naturally detect and trigger cell death in tumors.(29:02) Quantum Biology & Healing Frequencies(41:13) The AI Pessimist: Planning for a Post-Human World(44:03) Reconnecting with NatureEpisode Websitewww.creativeprocess.info/podInstagram:@creativeprocesspodcast
Cancer and heart disease claim the lives of more people each year, while diseases such as obesity and diabetes can keep us from fully enjoying our prime years. Lifestyle changes can be daunting, but John Bradshaw and cardiologist Dr. James Marcum discuss tangible steps you can take and how adding the power of God can make all the difference in your journey to overcome disease.
Cancer and heart disease claim the lives of more people each year, while diseases such as obesity and diabetes can keep us from fully enjoying our prime years. Lifestyle changes can be daunting, but John Bradshaw and cardiologist Dr. James Marcum discuss tangible steps you can take and how adding the power of God can make all the difference in your journey to overcome disease.
What if you are single and living in the life. How does dating look for you? What are the pitfalls? I talk to Jeff about how his dating life has been. Knowing that he is dating but not relationshipping. Find out his hurdles
1月23日OAのゲストは、NPO法人 日本ファイバーリサイクル連帯協議会(JFSA) 理事長の依知川守さんです。 日本で集めた衣類等のリサイクル、リユース販売を通じて パキスタンのスラムに暮らす子供たちの 自立を目指した支援活動を続けているJFSA。 なぜこのような取り組みを始めたのか? その理念や具体的活動内容を伺っていきます。 あなたにも何か協力できることがあるかも知れません! NPO法人日本ファイバーリサイクル連帯協議会 https://jfsa.jpn.org <オンエア楽曲> The Aay Jays『The Aay Jays Theme』
Wenn man ein grundsätzliches Verständnis für die Funktion von Östradiol und Progesteron hat, kann man die hormonellen Übergangsphasen im Leben einer Frau viel besser verstehen – und die vermeintlich unerklärlichen Symptome, mit denen sie einher gehen können. Das gilt nicht nur in der Perimenopause, sondern auch in der Zeit danach, der Postmenopause. Diana im Gespräch mit Gynäkologin, Autorin und Medfluencerin Dr. Judith Bildau über schlechten Schlaf nach der letzten Regelblutung, urogenitale Beschwerden, die erst einige Jahre später kommen, Hormondosierungen 60plus und welche Vorsorgeuntersuchungen sie für besonders unterschätzt hält.INFOS ZUR FOLGE:Hier geht's zur Website von Dr. Judith Bildau.Hier geht es zu Judith auf Instagram.Hier geht es zu Judiths aktuellem Buch, das im Oktober bei Droemer Knaur erschienen ist: „Body in Balance“.Hier geht es zu Judiths letztem Buch: „Raus aus dem Hormonkarussell“, erschienen bei Gräfe und Unzer GU im April 2024.Hier geht es zu ihrer Online-Sprechstunde bei wexxeljahre.de.Hier geht es zum Newsletter "Saisonwechsel" von der BRIGITTE.Hier geht es zum meno_brigitte-Insta-Account.Hier geht es zu Dianas Instagram.Hier geht es zu Julias Instagram.Auch interessant:Hier geht es zur MENO AN MICH Folge Nr. 40 "Untenrum Unbehagen: Scheidentrockenheit" mit Dr. Katrin Schaudig.Hier geht es zu Folge Nr. 85 "Kaputte Nächte – schlechter Schlaf in der Gynäkologie-Praxis" mit Dr. Katrin Schaudig.Hier geht es zur Folge Nr. 132 "Und danach? Die Postmenopause." mit Dr. Katrin Schaudig.Hier geht es zur Folge Nr. 16 "Auch wach? Besser schlafen in der Lebensmitte" mit Dr. Beate Paterok.+++ Weitere Infos zu unseren Werbepartnern findet Ihr hier: https://linktr.ee/menoanmich +++WEITERE ANGEBOTE aus der BRIGITTE Redaktion:Krafttraining-Kurs 50 plus der BRIGITTE Academy: Forever Fit On Demand Kurs von BRIGITTE ACADEMY.Masterclass Finanzen (aus unserer Eigenwerbung in dieser Folge, der Early Bird Rabatt gilt bis zum 8. September): academy.brigitte.de/masterclass?utm_source=menoanmich&utm_medium=podcast&utm_campaign=mcf-premium-kh11&utm_term=shopSkin-Code-Kurs mit Dermatologin Dr. Yael Adler: brigitte.de/meno-skinOn Demand Video-Kurs "Wechseljahre: Wissen, was hilft": https://academy.brigitte.de/course/wechseljahre?utm_source=podcast&utm_medium=meno&utm_campaign=wechseljahreKostenloses Webinar Rentenlücke berechnen: https://academy.brigitte.de/webinar-aufzeichnung-rentenluecke-berechnenETF Kurs: https://academy.brigitte.de/course/etf-kurs?utm_source=menoanmich&utm_medium=podcast&utm_campaign=etf-kurs-mEs gibt auch einen MENO AN MICH-Rabattcode, MENO15 (gilt für viele BRIGITTE-Angebote). Ihr habt Anregungen, wollt uns Eure Geschichte erzählen oder selbst bei uns zu Gast im Podcast sein? Dann schreibt uns beiden persönlich, worüber Ihr gern mehr wissen würdet, was Euch bewegt, rührt, entsetzt und Freude macht an podcast@brigitte.de. Wir freuen uns auf Euch! Und bewertet und abonniert unseren Podcast gerne auch auf Spotify, iTunes, Amazon Music oder Audio Now. Noch mehr spannende Beiträge findet Ihr zudem auf Brigitte.de sowie dem Instagram- oder Facebook-Account von BRIGITTE –schaut vorbei! +++Unsere allgemeinen Datenschutzrichtlinien finden Sie unter https://datenschutz.ad-alliance.de/podcast.html +++Wir verarbeiten im Zusammenhang mit dem Angebot unserer Podcasts Daten. Wenn Sie der automatischen Übermittlung der Daten widersprechen wollen, klicken Sie hier: https://datenschutz.ad-alliance.de/podcast.htmlUnsere allgemeinen Datenschutzrichtlinien finden Sie unter https://art19.com/privacy. Die Datenschutzrichtlinien für Kalifornien sind unter https://art19.com/privacy#do-not-sell-my-info abrufbar.
Dr. Phil sits down with Roshin and Tyler, whose extraordinary true story has captivated millions online. At just 13 years old, Roshin fled an abusive home to survive. Unbeknownst to her, a police officer named Tyler was part of the search team that night. Fifteen years later, they reconnected while working together at the sheriff's department, fell in love, and got engaged. In this powerful episode, they reveal the harrowing details of Roshin's escape, her struggles in foster care, and the incredible twist of fate that brought them together,proving that hope and healing are possible even after the darkest chapters.Thank you to our sponsors:NMLS 182334, https://nmlsconsumeraccess.org APR for rates in the 5s start at 6.196% for well qualified borrowers. Call 888-841-1319, for details about credit costs and terms. Or https://americanfinancing.net/Phil Chapter: Don't wait! If you're on Medicare or will be soon, reach out to Chapter. Call: (352)-845-0659 or go to https://askchapter.org/ to learn about your Medicare options and get help finding ways to save money.Watch Dr. Phil on Linear (Subscriptions needed):Spectrum/Charter - https://www.spectrum.com/cable-tv/channel-lineup (Search for Envoy TV; Channel may vary by location)Frndly TV - https://watch.frndlytv.com/channel/live/envoy_tvFAST (No subscriptions needed):SamsungTV Plus - Channel 2977 or found in the category Lifestyle & Pop CultureLocal Now - Download the app on your CTV or stream via Web https://localnow.com/channels/envoy-fastVIDAA on Hisense TV's:Watch on Hisense TV's with VIDAA OS or download the VIDAA App:IOS: https://apps.apple.com/gb/app/vidaa/id1526408639Google Play: https://play.google.com/store/apps/details?id=com.universal.remote.multi&hl=en_USSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Most brain decline, mood instability, and impulsive behavior start with a breakdown in how the brain's immune cells produce and use energy. This episode shows how mitochondrial health inside microglia influences cognition, emotion, and long-term brain resilience, and how everyday inputs quietly push those systems toward damage or repair. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Dr. David Perlmutter, a board-certified neurologist and six-time New York Times bestselling author whose work focuses on the intersection of neurology, nutrition, metabolism, and brain health. A Fellow of the American College of Nutrition and member of the Editorial Board of the Journal of Alzheimer's Disease, Dr. Perlmutter brings decades of clinical and research experience to this conversation on how inflammation and mitochondrial function shape the brain across the lifespan. Together, they explore how microglial cells shift their behavior based on metabolic conditions, and how those shifts influence neurodegeneration, emotional regulation, impulse control, and cognitive performance. The discussion covers real-world inputs that shape these systems, including sleep optimization, fasting, ketosis, glucose regulation, gut signaling, environmental toxins, and tools referenced in the episode such as red and infrared light, 40 Hz light and sound, hyperbaric oxygen, lithium, nicotine, supplements, nootropics, GLP-1 agonists, and dietary approaches like carnivore and ketosis. The conversation connects brain biology to lived experience, showing how metabolism influences behavior, decision making, and long-term human performance through a Smarter Not Harder lens. You'll Learn: • How microglia shift between supportive and destructive states and why metabolism drives that change • How mitochondrial function inside immune cells influences inflammation and brain resilience • How inflammation affects the prefrontal cortex, impulse control, and reward-driven behavior • What the episode says about GLP-1 agonists and behavior changes like reduced cravings and gambling • How gut-derived signaling and short-chain fatty acid balance (butyrate vs propionate) relates to brain function • How tools like red and infrared light, hyperbaric oxygen, and 40 Hz light and sound connect to microglia • The lifestyle levers discussed in the episode: sleep optimization, fasting, ketosis, glucose control, and toxin reduction • The compounds mentioned, including lithium, nicotine, urolithin A, CoQ10, rosmarinic acid, and dihydromyricetin Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off. BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide Establish a powerful foundation for sustained wellness with Pique. Unlock 20% off: piquelife.com/DAVE Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: microglia brain health, brain immune system mitochondria, neuroinflammation podcast, mitochondrial dysfunction brain, david perlmutter podcast, dr david perlmutterneurologist, grain brain author podcast, alzheimers brain metabolism, parkinsons microglia, autism brain inflammation, gut brain immune signaling, short chain fatty acids brain, butyrate propionate brain, glp-1 brain behavior, glp-1 addiction research, red light therapy brain, infrared light mitochondria brain, 40 hz light sound brain, hyperbaric oxygen brain health, lithium microglia brain Resources: • Learn More About Dr. Perlmutter at: https://drperlmutter.com/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 - Introduction 1:45 - Autism Spectrum 4:38 - Alzheimer's & Beta Amyloid 7:02 - Brain Immune Cells 8:06 - GLP-1 & Parkinson's 10:44 - M1 vs M2 Microglia 13:08 - Pharmaceutical Microdosing 15:51 - Gene Therapy 19:09 - Mold & Toxins 21:58 - Environmental Pollution 26:05 - MPTP Discovery 29:07 - Healing Interventions 31:39 - Light & Sound Therapy 36:35 - Mitochondrial Function 44:57 - Inflammation & Prefrontal Cortex 48:00 - GLP-1 Global Impact 52:11 - Mitochondrial Community 56:05 - Consciousness & The Field 1:00:00 - Psychedelics 1:01:59 - Love & Judgment 1:06:35 - Death & Knowing 1:09:06 - Heart-Brain Connection 1:11:06 - Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Send us a textSwinging Isn't What You Think: Busting the Biggest Lifestyle Myths | Episode 228In this episode of The Swing Nation Podcast, the top-rated podcast about non-monogamy and swinging, Dan and Lacy break down Swinger Myths vs. Reality and tackle some of the biggest misconceptions about the lifestyle.They dive into common myths like “everyone has to hook up,” “only certain body types are welcome,” and the idea that you must look or perform a certain way to belong. Dan and Lacy explain how much choice, autonomy, and diversity actually exist in the lifestyle, and why pressure to participate or fit a mold is one of the biggest misunderstandings outsiders—and even newcomers—have.Drawing from real-life experiences, they talk about how confidence, communication, and comfort matter far more than appearance or expectations. Whether you're curious about the lifestyle or already part of the community, this episode helps strip away the stigma and replace it with honest, no-BS insight into how things really work.Electric Pleasures Events- The Swing Nation - Main Website Quick Navigation Website: -- (Find all our social media links & more!)- Swinger Society - Our Website to meet, connect & events Swinger Society Discord Our Facebook Group- Swinger Websites -Kasadie 90 day free trialUsername: TheSwingNation SDC 14 day free trial Username: TheSwingNation** Use code 36313 for 14 days free! **- Merch & More -Order Your Merch Here!- Lacy's Fun Links -VIP OnlyFansPREMIUM OnlyFans-- THANK YOU TO OUR SPONSORS --IKNOWMYSTATUS: Test Like a Porn StarUse Code LifeStyle and get 15% OFFShameless Care: ED MedicationUse Code TSN at checkout for $15 off your order!Promescent® Make Love Longer, It's Time for Great SexUse Code SwingNation for 5% off!Sing it Bikinis: adjustable one-size styles, thoughtfully crafted to flatter every body type.Support the show- Thank you for the support! -
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Let's talk about the lifestyle baby! I'm reconnecting with my lifestyle crew and it feels so good to be back! I'm sharing my journey on how I discovered the lifestyle, what the culture is like, how my sexuality evolved and how I plan to move forward being with Mr. Right. I also share hot tales and why this episode is a day late...priorities Cravers! XOXOGet 20% OFF my favorite toys at TracysDog.com using code CRAVERS20
Best-selling author Jennifer Wallace stops by studio 1A to offer a guide to connection and lifting each other up, the topic of her new book “Mattering: The Secret to a Life of Deep Connection and Purpose”. Also, Al Roker travels to the Kennedy Space Center to tour Nasa's Artemis II Rocket and chat with the crew before their historic mission next month. And Today lifestyle and fashion contributor, Melissa Garcia, shares the winter products to help keep you warm, hydrated, and stress-free until spring arrives. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Five years ago, In The LOOP started with an iPhone, a truck seat, and a simple desire to tell stories that mattered. Today, it's grown into a platform with over 250 episodes, a loyal community, and a new chapter as part of the Cowboy Channel.In this solo reflection episode, In The LOOP Podcast host Jordan Jo looks back on the journey — from the early days of breakaway roping's professional rise to the moments, conversations, and people that shaped the heart of the show. She shares how rodeo opened doors, introduced lifelong friendships, and ultimately laid the foundation for a podcast rooted in storytelling, curiosity, and faith.Jordan Jo also pulls back the curtain on what's ahead. As 2026 begins, In The LOOP is entering a more intentional season — one focused on deeper, wiser conversations and the pursuit of bold goals within the Western industry. This year's episodes will center on women who are building, leading, competing, and evolving — both inside and outside the arena — alongside the men who support, challenge, and champion them.From navigating identity and leadership to building businesses, making hard decisions, and celebrating wins we don't talk about enough, this episode sets the tone for what's next: honest dialogue, courageous questions, and conversations that matter.If you've been here since the beginning — or you're just joining — this episode is an invitation to step into the next chapter together.
(January 22, 2026) A surprising beneficiary of weight-loss drug? U.S. Airlines. ‘Death Café’ will explore end-of-life issues, over refreshments. Beyond Meats tests protein beverages in bid for much needed growth. VA promises hundreds of tiny homes on its West L.A campus; veterans want something nicer.See omnystudio.com/listener for privacy information.
Licensed mental health counselor and author Jill Sylvester discusses strategies and tips, along with trusting your own inner voice, to live your very best life. Today's discussion: Guest Interview with Astrologer Jill JardineContact Jill SylvesterFollow us on IG @jillsylvesterSend us questions or feedback at jill@jillsylvester.comFor more information or to check out our other products: www.jillsylvester.comThanks to Carl Sylvester for production, Jon Grabowski for sound engineering, Tracy Colucci for newsletter creation, and Good Health in Hanover Massachusetts for sponsorship. With their support, the TYI podcast is made possible for YOU to gain personal development strategies and live your best life. Thanks for listening!
Send us a textChoose Self-Care or Choose ResentmentMost resentment isn't caused by other people.It's caused by what you've been neglecting in yourself.In this Lifestyle of Fitness Office Hours, Michael Caulo breaks down why self-care isn't selfish—and how neglecting it quietly turns into burnout, resentment, and emotional dysregulation.This isn't motivational fluff. It's behavioral science, physiology, and real-world application.Check out the Lifestyle of Fitness blog post for the full breakdown!
Does your financial plan have the same flexibility you want your life to?In this episode, we delve into the importance of not just planning for basic financial stability, but also planning for a comfortable and flexible lifestyle in your retirement years. We discuss the variables that impact financial planning, stress testing for potential economic factors, and how an individualized lifestyle buffer can provide peace of mind.
Not Just Fluff: Pet wellness from the pros at Banfield Pet Hospital
How do you know if the cat on your lap, or the dog at your feet, has the right care plan? Just like people, the needs of our pets change with age, lifestyle, and environment. In this episode, Hannah Shaw chats with Dr. Elizabeth Thompson, Chief of Staff at Banfield Pet Hospital in Mt. Hood, Oregon, about what it really takes to keep pets thriving long term. Together, they talk through how lifestyle factors shape preventive care, how to make decisions around vaccines, nutrition, and travel, and why it's important to have open conversations about cost, wellness plans, and pet insurance. Dr. Thompson also shares real stories from the clinic that show how proactive care can catch hidden issues early, and even save lives. If you are ready to team up with your veterinarian on preventive care, this episode is for you! Follow us on social media!Facebook: Banfield Pet HospitalInstagram: @banfieldpethospitalDisclaimer: The information provided in this podcast is for informational purposes only and is not a substitute for professional veterinary advice. Always consult a veterinarian with any questions regarding your pet's health or medical condition. Never disregard or delay seeking professional veterinary advice based on information from this podcast.The listener question featured in this episode is a hypothetical scenario presented by an actor. It does not reflect the views or experiences of an actual listener.
Part 2: In September 2020 in Westlake Village, California, a speeding SUV struck and killed two young brothers in a crosswalk. The driver Rebecca Grossman claims it was a tragic accident, but she was found guilty of two counts of murder and sentenced to 15 years to life. Now her husband speaks out, sharing her remorse, regrets, and what they say is her truth. Thank you to our sponsors:NMLS 182334, https://nmlsconsumeraccess.org APR for rates in the 5s start at 6.196% for well qualified borrowers. Call 888-841-1319, for details about credit costs and terms. Or https://americanfinancing.net/PhilChapter: Don't wait! If you're on Medicare or will be soon, reach out to Chapter. Call: (352)-845-0659 or go to https://askchapter.org/ to learn about your Medicare options and get help finding ways to save money.Watch Dr. Phil on Linear (Subscriptions needed):Spectrum/Charter - https://www.spectrum.com/cable-tv/channel-lineup (Search for Envoy TV; Channel may vary by location)Frndly TV - https://watch.frndlytv.com/channel/live/envoy_tvFAST (No subscriptions needed):SamsungTV Plus - Channel 2977 or found in the category Lifestyle & Pop CultureLocal Now - Download the app on your CTV or stream via Web https://localnow.com/channels/envoy-fastVIDAA on Hisense TV's:Watch on Hisense TV's with VIDAA OS or download the VIDAA App:IOS: https://apps.apple.com/gb/app/vidaa/id1526408639 https://play.google.com/store/apps/details?id=com.universal.remote.multi&hl=en_USSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
On today's episode, we hear about: A woman wondering how to find common ground with her husband about productivity A woman whose mother-in-law won't stop one-upping her and her husband A woman trying to stop her friend from going back to an abusive ex Next Steps: ❤️ Get away with your spouse today!
Women with uterine fibroids face a significantly higher long-term risk of heart disease, meaning fibroids act as an early warning sign of deeper cardiovascular strain rather than a localized reproductive issue The increased risk shows up early, often years before traditional heart disease symptoms appear, giving you a key window to address underlying metabolic and vascular stress Fibroids are linked to chronic inflammation, impaired blood vessel function, and disrupted energy metabolism, all of which contribute to heart disease development over time Addressing root causes such as low cellular energy, poor metabolic flexibility, and vascular stress helps reduce both fibroid progression and cardiovascular risk Lifestyle strategies that support energy production, reduce inflammation, and improve circulation shift your body out of survival mode and lower long-term heart disease risk
Erin Port of Simple Purposeful Living shares how tiny tweaks can make a good life even betterSee omnystudio.com/listener for privacy information.
Dr. Phil sits down with 25-year-old Blake Resnick, the founder of BRINC, to talk about how a teen who loved building drones ended up taking on Chinese tech giants in America's skies. Blake explains how the Las Vegas Route 91 shooting changed everything for him, why he started cold-calling SWAT teams as a teenager, and how that led to his life-saving Lemur and Responder drones now used by major law-enforcement agencies. And former NYPD Chief of Department John Chell joins the conversation to share how critical drones have become to keeping his officers and the public safe, and why he believes every police department in America should be using them. Thank you to our sponsors:NMLS 182334, https://nmlsconsumeraccess.org APR for rates in the 5s start at 6.196% for well qualified borrowers. Call 888-841-1319, for details about credit costs and terms. Or https://americanfinancing.net/PhilChapter: Don't wait! If you're on Medicare or will be soon, reach out to Chapter. Call: (352)-845-0659 or go to https://askchapter.org/ to learn about your Medicare options and get help finding ways to save money.Watch Dr. Phil on Linear (Subscriptions needed):Spectrum/Charter - https://www.spectrum.com/cable-tv/channel-lineup (Search for Envoy TV; Channel may vary by location)Frndly TV - https://watch.frndlytv.com/channel/live/envoy_tvFAST (No subscriptions needed):SamsungTV Plus - Channel 2977 or found in the category Lifestyle & Pop CultureLocal Now - Download the app on your CTV or stream via Web https://localnow.com/channels/envoy-fastVIDAA on Hisense TV's:Watch on Hisense TV's with VIDAA OS or download the VIDAA App:IOS: https://apps.apple.com/gb/app/vidaa/id1526408639Google Play: https://play.google.com/store/apps/details?id=com.universal.remote.multi&hl=en_USSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Mississippi's “miracle” is a literacy glow-up: science of reading, phonics, coaching, early screening, and accountability. A blueprint, not luck. Mississippi went from “dead last” vibes to top-tier literacy gains by sticking to the science of reading: phonics-based instruction, statewide coaching, early screening, and a tough “third-grade gate.” Here's what actually changed and why this “miracle” looks more like a repeatable blueprint for fixing reading nationwide. Thank you to our sponsor:NMLS 182334, https://nmlsconsumeraccess.org. APR for rates in the 5s start at 6.196% for well qualified borrowers. Call 888-841-1319, for details about credit costs and terms. Or https://americanfinancing.net/PhilWatch Dr. Phil on TV (Subscriptions needed):Spectrum/Charter - https://www.spectrum.com/cable-tv/channel-lineup (Search for Envoy TV; Channel may vary by location)Frndly TV - https://watch.frndlytv.com/channel/live/envoy_tvFAST (No subscriptions needed):SamsungTV Plus - Channel 2977 or found in the category Lifestyle & Pop CultureLocal Now - Download the app on your CTV or stream via Web https://localnow.com/channels/envoy-fastVIDAA on Hisense TV's:Watch on Hisense TV's with VIDAA OS or download the VIDAA App:IOS: https://apps.apple.com/gb/app/vidaa/id1526408639Google Play: https://play.google.com/store/apps/details?id=com.universal.remote.multi&hl=en_USSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Your body does not fail all at once. Aging starts when cells quietly shift into survival mode and never come back out. In this episode, you go inside the thinking of a true medical outlier to understand how stress, travel, toxins, and metabolic overload reprogram cells, shut down energy, and accelerate aging, and how restoring mitochondrial function can reverse that trajectory from the inside out. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Theodore Achacoso and Boomer Anderson, leaders in Health Optimization Medicine and Practice. Dr. Achacoso is a physician-scientist and the founding pioneer of Health Optimization Medicine, known for his work on cellular networks, metabolomics, and mitochondrial function. Boomer Anderson is the CEO of Smarter Not Harder and Troscriptions, where he focuses on translating complex biology into practical tools for human performance and longevity. Together, they unpack how cells respond to perceived threats through the Cell Danger Response, why mitochondria control energy, inflammation, and repair, and why chasing disease labels misses the real drivers of aging. The discussion covers methylene blue as an electron recycler, why LDL cholesterol plays a role in detoxification and immune signaling, how fasting and ketosis shift metabolism between repair and growth, and why sleep optimization, circadian rhythm, and light exposure matter even more when you travel. They also explore neuroplasticity, consciousness, nootropics, supplements, and why health optimization works best when you restore balance instead of forcing outcomes. You'll Learn: • What the Cell Danger Response is and how it reshapes aging and performance • How mitochondria sense stress before symptoms appear • Why cellular energy controls resilience, sleep, and longevity • How methylene blue supports mitochondrial electron flow • Why fasting and ketosis shift metabolism between repair and growth • How travel, light, and circadian disruption affect aging • Why very low LDL can impair detoxification and immune signaling • Why real anti-aging starts at the cellular level, not with disease labels Thank you to our sponsors! AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers. Screenfit | Get your at-home eye training program for 40% off using code DAVE at www.screenfit.com/dave. Puori | Use code DAVE at puori.com/DAVE to get 32% off your Puori Fish Oil when you start a subscription. You save more than $18. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cell danger response podcast, mitochondria aging, mitochondrial dysfunction aging, health optimization medicine, dr ted achacoso, boomer anderson, troscriptions, troscriptions methylene blue, methylene blue mitochondria, methylene blue biohacking, cellular aging podcast, anti aging mitochondria, metabolic stress aging, fasting ketosis metabolism, mitochondrial energy production, neuroplasticity mitochondria, sleep optimization aging, functional medicine mitochondria, smarter not harder biohacking, dave asprey mitochondria Resources: • Get A Discount On All Troscription Products with code ‘dave' at: https://troscriptions.com/ • Learn More About Methylene Blue From My Full Masterclass Covering The Topic: https://daveasprey.com/mb/ • Discover More About The ‘Health Optimization Medicine and Practice' From Our Guests: https://homehope.org/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Trailer 1:25 – Introduction & Guest Background 3:11 – Health Optimization Medicine Origins 4:26 – Root Causes of Health vs Disease 6:15 – Biohacking & Self-Experimentation 8:19 – Medicinal Plants & Nootropics 11:25 – Travel & Jet Lag Solutions 13:42 – Cell Danger Response 17:38 – Metabolites & Cellular Health 18:57 – LDL & Lipopolysaccharides 20:42 – Cellular Model & First Principles 22:55 – Consciousness & Mitochondria 25:46 – Nanotechnology Research 28:55 – Giving Back & Service 31:17 – Blue Cannatine Development 34:48 – Methylene Blue Products 36:22 – Metformin Discussion 38:00 – Dosing & Cordycepin 41:25 – Closing & Discount Code See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.