Podcasts about CNS

Fluphenazine is a high-potency typical antipsychotic that primarily acts as a dopamine D2 receptor antagonist in the mesolimbic pathway, reducing positive symptoms of schizophrenia. Extrapyramidal symptoms (EPS), such as dystonia, akathisia, and parkinsonism, are common due to potent D2 blockade in the nigrostriatal pathway. Neuroleptic malignant syndrome (NMS), though rare, is a life-threatening adverse effect characterized by rigidity, hyperthermia, altered mental status, and autonomic instability. CYP2D6 inhibitors (e.g., fluoxetine, paroxetine) can increase fluphenazine plasma concentrations, potentially raising the risk of toxicity and side effects. Concomitant use of fluphenazine with CNS depressants (e.g., alcohol, benzodiazepines) can enhance sedation and respiratory depression.

Send us a textAmy Berger is a returning guest on our show! Be sure to check out her appearances on episode 47, episode 68, and episode 354 of Boundless Body Radio!Amy Berger, MS, CNS, is a U.S. Air Force veteran and Certified Nutrition Specialist who specializes in helping people do “Keto Without the Crazy.”™ She has a master's degree in human nutrition and writes about a wide range of health and nutrition-related topics, such as insulin, metabolism, weight loss, diabetes, thyroid function, and more.Amy is the author of The Alzheimer's Antidote: Using a Low-Carb, High-Fat Diet to Fight Alzheimer's Disease, Memory Loss, and Cognitive Decline, and The Stall Slayer: Seven Roadblocks to Keto Fat Loss and What to Do About Them. She is also the co-author of End Your Carb Confusion: A Simple Guide to Customize Your Carb Intake for Optimal Health.Amy spent years doing what nutrition and health experts claimed to lose weight but failed to experience the expected results. You can read her blog at www.tuitnutrition.com, where Amy's readers value her clever and humorous writing style, and her ability to translate scientific research jargon and gobbledygook into plain English.Find Amy at-Consultations- https://stallslayer.com/consultation/ YouTube- Tuit NutritionTW- @Tuit NutritionPatreon- Tuit Nutrition Online courses- http://adaptyourlifeacademy.com/ Funny- This Is Why Healthy Eating is Hard- Funny or DieAmy's blog post that broke my brain about gluconeogenesis!Find Boundless Body at- myboundlessbody.com Book a session with us here!

Getting a good night's sleep is something that benefits everyone. And if you're someone who's living with MS, it's perhaps even more important. But research suggests that more than half the people living with MS experience poor sleep.    Dr. Katie Siengsukon, the Director of the Sleep, Health, and Wellness Lab at the University of Kansas Medical Center Department of Physical Therapy and Rehabilitation Science, returns to the podcast to discuss the importance of good sleep hygiene, along with steps you can take to improve the quality of your sleep. We're also explaining how changes in U.S. public policy will impact people with MS. We'll tell you about an algorithm developed at Duke University that can predict (with 80-90% accuracy!) whether someone's MS symptoms will worsen in the weeks ahead. We'll share study results that show MS accelerates biological aging among children and teens with MS. We'll explain why this finding can also be applied to adults with MS, and what it means. And we'll tell you about the biotech start-up that has succeeded at bringing the brains of people who have passed away back to life, and we'll explain why that can have a major impact on CNS disease research. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Sleep Hygiene and MS  :22 How public policy changes in the U.S. will impact people with MS  1:18 What if you knew when an MS symptom was going to worsen?  6:18 Study results show MS accelerates biological aging in children  9:04 How re-animated human brains could accelerate CNS research (And which company is doing it!)  12:00 Dr. Katie Siengsukon discusses the importance of good sleep hygiene for people living with MS  15:37 Share this episode  33:32 Have you downloaded the free RealTalk MS app?  33:52 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/407 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Become an MS Activist https://nationalmssociety.org/advocacy Act Now! Contact Your Senators About Medicaid and Health Coverage https://nmss.quorum.us/campaign/127768 STUDY: Performance of Machine Learning Models for Predicting High-Severity Symptoms in Multiple Sclerosis https://nature.com/articles/s41598-024-63888-x STUDY: Epigenetic Aging in Pediatric-Onset Multiple Sclerosis https://neurology.org/doi/10.1212/WNL.0000000000213673 Bexorg https://bexorg.com Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 407 Guest: Dr. Katie Siengsukon Privacy Policy

Struggling to keep the nervous system straight—or just worried you'll blank on that -70 mV resting potential?

Julie Poteet, OD, MS, CNS, FOWNS, joins Marc R. Bloomenstein, OD, FAAO, to discuss the role of nutrition in ocular health. Dr. Poteet shares insights into how she integrates the discussion of nutrition into each patient's exam, highlighting the use of diagnostic imaging to show patients a visualization of their eye health. She also discusses the evidence and data behind food's impact on vision.

Forbes, NYT, The Huffington Post, CNN, MSNBC have featured Renown Nutritionist & Fitness Expert. Best-selling author, Jonny Bowden, PhD, CNS.His first Love is MUSIC, but started out as a professional musician & played all over New York CIty, playing jazz, pop, Broadway, nightclub acts, Jonny studied with the great Herbie Hancock & was as a pianist at the Alvin Ailey Dance Studios. He has a Master's degree in psychology BUT after learning the lifestyle & physical effects that the professional music & entertainment scene can bring, He was able to beat his addiction to smoking, drugs & alcohol.Jonny got a PhD in holistic nutrition and earned board certification and the CNS (Certified Nutrition Specialist) designation from the College's Certifying Board of Nutrition Specialists.He is a frequent guest on television and radio, he has appeared on Fox News, ABC, NBC, and CBS as an expert on nutrition, weight loss, and longevity. the author of thirteen books on health, healing, food and longevity including several best-sellers, “The 150 Healthiest Foods on Earth” and “Living Low Carb” & "The Most Effective Ways To Live Longer".Dr. Jonny has contributed to articles for dozens of national publications (print and online) including The New York Times, The Wall Street Journal, Forbes, The Daily Beast, The Huffington Post, Vanity Fair Online, Time, Oxygen, Marie Claire, Diabetes Focus, GQ, US Weekly, Cosmopolitan, Self, Fitness, Family Circle, Allure, Men's Heath, Prevention, In Style, Natural Health, and many other publications. He appears regularly as an expert on ABC-TV Los Angeles. ~ JonnyBowden.com2025 Building Abundant Success!!All Rights Reserved © 2025  Building Abundant Success!!Join Me on ~ iHeart Media@ https://tinyurl.com/iHeartBASSpot Me on Spotify: https://tinyurl.com/yxuy23baAmazon Music ~ https://tinyurl.com/AmzBAS  

This is the latest episode of the free DDW narrated podcast, titled “Innovative uses for biomarkers in drug discovery”, which covers three articles written for DDW Volume 24 – Issue 4, Fall 2023. They are called: “Advances in neuroscience drug discovery”, “Putting human data at the centre of drug discovery”, and “The era of precision neuroscience”. In the first article, Lu Rahman looks at neuroscience drug discovery – advances and challenges – and how breakthroughs in this field are helping address areas of unmet need. In the second article, James Peach, Co-Founder and CEO of Human Centric Drug Discovery (HCDD), an Oxford University spin-out improving neurology drug discovery by bringing more human data to the process, shares insight with me.  In the third article, Dr Steve Gardner, CEO of the computational biology company PrecisionLife, explores the challenges of achieving precision medicine in complex CNS conditions and explains how new precision neuroscience approaches are benefitting pharmaceutical companies who are again investing in the field to develop better treatments for neurological and neuropsychiatric diseases.

Dr. Sam Berne is a super star holistic optometrist celebrated for his innovative approaches to eye health and wellness. He is the author of Vital Vision. Join The First Lady of Nutrition for an eye-opening conversation that goes far beyond glasses and eye drops.  Together, Ann Louise and Dr. Berne explore the groundbreaking idea that vision is not just about the eyes—but a dynamic connection between the brain, body, and soul. With stories of reversing cataracts, improving macular degeneration, and dissolving floaters naturally, Dr. Berne shares why you don't have to live out your doctor's diagnosis. From post-COVID vision issues to the rise in nearsightedness from screen time, this episode covers practical steps to protect and restore your eyesight—including what to do for glaucoma, night blindness, dry eyes, and more. Learn why the liver and gallbladder are critical to eye health, why early morning sunlight matters, and how simple therapies like “palming” can make a big difference. Plus, the truth about blue light, vitamin A, brain injuries, and why your glasses may be doing more harm than good. This podcast is a must-listen for anyone who wants to see life more clearly—naturally.  Learn more about Dr. Berne at https://www.drsamberne.com/. The post Casting Your New Vision – Episode 196: Dr. Sam Berne first appeared on Ann Louise Gittleman, PhD, CNS.

Nutrition discussion with an optometrist. Dr. Julie Poteet, OD, MS, CNS, FOWNS Dr. Julie Poteet, OD, MS, CNS, FOWNS is an industry key opinion leader in nutrition and ocular health. Master of Science in human nutrition and functional medicine; one of the first ODs to become a Certified Nutrition Specialist; frequent lecturer and author on nutrition and ocular health. Honored to have served as immediate past president of the Ocular Wellness & Nutrition Society, serves on the Board of the American Nutrition Association BCNS, the Macular Degeneration Association, Women in Optometry, and the Ocular Wellness & Nutrition Society.

Dexmedetomidine — or “Dex” — has become one of the most intriguing and versatile drugs in the anesthesia world. In this episode of Anesthesia Alchemy with hosts Lynn Macksey, MSN, CRNA and Garry Brydges, PhD, DNP, MBA, CRNA, ACNP-BC, FAAN dive deep into the pharmacology, clinical application, and emerging research surrounding this alpha-2 agonist. Here's some of what we discuss in this episode:

Nutrition discussion with an optometrist. Chronic inflammation, oxidative stress, and excess sugar lead to accelerated aging and chronic diseases, including diseases of the eyes. Nutrition is the starting point to target these risk factors and should be a component of a healthy eye care routine. On this episode of Live Foreverish, Dr. Mike and Dr. Crystal have an insightful discussion with Dr. Julie Poteet, a Doctor of Optometry and Certified Nutrition Specialist. Discussion highlights include how nutrition impacts ocular health, top dietary considerations for cataracts, macular degeneration, glaucoma, and the important work of the Ocular Wellness & Nutrition Society. Dr. Julie Poteet, OD, MS, CNS, FOWNS Dr. Julie Poteet, OD, MS, CNS, FOWNS is an industry key opinion leader in nutrition and ocular health. Master of Science in human nutrition and functional medicine; one of the first ODs to become a Certified Nutrition Specialist; frequent lecturer and author on nutrition and ocular health. Honored to have served as immediate past president of the Ocular Wellness & Nutrition Society, serves on the Board of the American Nutrition Association BCNS, the Macular Degeneration Association, Women in Optometry, and the Ocular Wellness & Nutrition Society.

In part one of this three-part series, Dr. Justin Abbatemarco and Dr. Sumanth Reddy discuss small vessel primary CNS vasculitis. Show reference: https://www.neurology.org/doi/10.1212/NXI.0000000000200397 

Dr. Justin Abbatemarco talks with Drs. Sumanth Reddy and Jeffrey Gelfand about the complexities of small vessel predominant primary CNS vasculitis, clinical features, and the impact of early intensive immunosuppressive therapy on remission.  Read the related article in Neurology® Neuroimmunology & Neuroinflammation.  Disclosures can be found at Neurology.org. 

With 93% of Americans now considered metabolically unhealthy, this episode is a wake-up call. The First Lady of Nutrition welcomes Ben Azadi—biohacker and author of the newly released book, Metabolic Freedom: A 30-Day Guide to Restore Your Metabolism, Heal Hormones & Burn Fat. It also explores the top hidden contributor to metabolic dysfunction—heavy metal toxicity—and why the most powerful biohack of all may be your thoughts.   In this inspiring conversation, Ben shares how he transformed his body and mind using ketosis—and why most people are doing keto all wrong. Ann Louise and Ben dive into the real keys to metabolic freedom, including how to test for ketosis (and why one method stands above the rest), the vital role of liver support, and what “metabolic flex days” can do to reset your system.   Ben also opens up about his childhood struggles with obesity and how his health journey lifted him out of depression and into clarity and confidence. According to Ben, we get thousands of chances a day to shift our body toward balance and healing. If you're looking to boost energy, burn fat, and truly feel good again, this podcast could be your roadmap to metabolic freedom.   Special Offer for our listeners: When you order Metabolic Freedom, you'll get access to a free bonus course—12 exclusive lessons on metabolism, including behind-the-scenes interviews. Visit metabolicfreedombook.com to learn more. The post Callin All Pet Parents! What You and Your Pet Need to Thrive – Episode 195: Angela Ardolino first appeared on Ann Louise Gittleman, PhD, CNS.

This episode is brought to you by Pique Teas, Z-Biotics and Caldera Lab. Dr. Brooke Scheller, DCN, CNS is back to take us on her personal journey of nearly four years without alcohol, revealing the profound impact it has had on her life and career. As she delves into the multifaceted effects of alcohol on health, including its influence on hormone balance and mental well-being, Dr. Scheller invites you to reconsider your relationship with alcohol. We explore the growing trend of "sober curious" and how societal attitudes toward alcohol consumption are shifting, especially among younger generations. By discussing the benefits of a sober lifestyle, nutrition, and the rise of non-alcoholic alternatives, Dr. Scheller challenges the stigma surrounding alcohol abstention and celebrates the empowerment that comes from choosing sobriety. Whether you're exploring sobriety or simply curious about its benefits, this episode offers valuable insights into living a healthier, alcohol-free life. Follow Brooke @drbrookescheller Follow Chase @chase_chewning ----- In this episode we discuss... (00:00) Exploring Alcohol's Impact on Health (10:08) Rise of the Sober Curious Movement (16:39) Transitioning to Alcohol-Free Life (27:57) Navigating Social Changes Without Alcohol (33:13) Alcohol's Impact on Hormones (45:37) Brooke's Personal Reflection and Choice to Go Alcohol-Free (56:45) Emerging World of Non-Alcoholic Beverages (01:09:39) Other Benefits of Alcohol-Free Living (01:19:11) Rethinking Alcohol's Impact on Health (01:24:12) What Modern Functional Sobriety and Wellness Really Looks Like ----- Episode resources: Get 20% off FOR LIFE of the best teas at https://www.PiqueLife.com/everforward  Save 10% on the drink before your drink with code EVERFORWARD10 at https://www.ZBiotics.com/everforward10  Save 20% on Father's Day skincare with code EVERFORWARD at https://www.CalderaLab.com Watch and subscribe on YouTube Brooke's first appearance in EFR 785: How Alcohol Affects Your Gut Microbiome, Brain Health, Hormones, Lowers Fertility, and How to Eat to Change How You Drink and watch on YouTube here

Featuring an interview with Dr Rinath M Jesselsohn, including the following topics: Evaluating first-line treatment of metastatic ER-positive, HER2-positive breast cancer: heredERA Breast Cancer study (0:00) Kuemmel S et al. heredERA Breast Cancer: A phase III, randomized, open-label study evaluating the efficacy and safety of giredestrant plus the fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection in patients with previously untreated HER2-positive, estrogen receptor-positive locally advanced or metastatic breast cancer. BMC Cancer 2024;24(1):641. Abstract  Treatment outcomes with CDK4/6 inhibitors and with elacestrant in real-world studies (4:13) Lloyd MR et al. CDK4/6 inhibitor efficacy in ESR1-mutant metastatic breast cancer. NEJM Evid 2024;3(5). Abstract  Lloyd M et al. Impact of prior treatment, ESR1 mutational (ESR1m) landscape, and co-occurring PI3K pathway status on real-world (RW) elacestrant outcomes in patients (pts) with hormone receptor-positive (HR+)/HER2-negative advanced breast cancer (aBC). San Antonio Breast Cancer Symposium 2024;Abstract PS7-05.  Evaluating the CNS activity of imlunestrant, an oral selective estrogen receptor degrader (SERD) (8:06) VandeKopple M et al. Preclinical characterization of imlunestrant, an oral brain-penetrant selective estrogen receptor degrader with activity in a brain metastasis (BM) model. ESMO Breast 2023;Abstract 41P.  Selective review of trials of oral SERDs in the adjuvant setting (11:27) A study of imlunestrant versus standard endocrine therapy in participants with early breast cancer (EMBER-4). NCT05514054 CME information and select publications

In this episode, I'm thrilled to welcome back Dr. Aaron Boster, he is a board-certified Neurologist specializing in Multiple Sclerosis and related CNS inflammatory disorders. Dr. Boster joins me to share his powerful ‘5 for 5' framework—five essential strategies to slow MS progression and improve your quality of life with multiple sclerosis. We break down each pillar: smoking cessation, exercise, nutrition, mindfulness, and choosing the most effective disease-modifying therapy. Dr. Boster offers practical advice that's easy to understand and apply, covering everything from hydration tips and vitamin D to how to make exercise a sustainable part of your MS lifestyle. If you're looking for expert MS management strategies, actionable exercises, and ways to support your MS journey, you won't want to miss this empowering conversation! Tune in for clear, actionable tips to take control of your MS and live your best life. About Dr. Aaron Boster: Aaron L Boster, MD, is a board-certified clinical neuroimmunologist specializing in Multiple Sclerosis. As a neuroimmunologist, Dr Boster provides diagnosis and treatment for all types of MS as well as a wide range of neuroimmunological conditions. He also provides medical management of refractory severe spasticity with expertise in intrathecal baclofen. Dr. Boster received his undergraduate degree from Oberlin College in Oberlin, Ohio and his medical degree from the University of Cincinnati College of Medicine in Cincinnati, Ohio. Dr Boster completed his internship and neurology residency through the University of Michigan in Ann Arbor, Michigan. He continued his training at Wayne State University in Detroit, Michigan, where he completed a fellowship focused on clinical neuroimmunology and multiple sclerosis. He has over a decade and a half of experience combating MS in the clinic and participating in MS clinical research. Connect with Dr. Aaron Boster: Twitter: https://twitter.com/aaronbostermd Youtube: https://www.youtube.com/c/AaronBosterMD Facebook: https://www.facebook.com/AaronBosterMD/ Website: https://bosterms.com/ Additional Resources: https://www.doctorgretchenhawley.com/insider Reach out to Me: hello@doctorgretchenhawley.com Website: www.MSingLink.com Social: ★ Facebook: https://www.facebook.com/groups/mswellness ★ Instagram: https://www.instagram.com/doctor.gretchen ★ YouTube: https://www.youtube.com/c/doctorgretchenhawley?sub_confirmation=1 → Game Changers Course: https://www.doctorgretchenhawley.com/GameChangersCourse → Total Core Program: https://www.doctorgretchenhawley.com/TotalCoreProgram → The MSing Link: https://www.doctorgretchenhawley.com/TheMSingLink

In this episode of Hope Natural Health, Dr. Erin chats w/guest Dr. Shayne Morris about the relationship between stress, your microbiome, and hormones.  Dr. Shayne Morris, Ph.D., CNS, MBA, is a trailblazer in the world of natural health and microbiome research. As the CEO of Systemic Formulas and Alimentum Labs, founded in the 1980s, Dr. Morris has dedicated his life to uncovering the incredible potential of the microbiome in transforming health. His cutting-edge supplements are recognized as industry leaders, blending the latest scientific advancements with ancient wisdom to create powerful, effective solutions. Passionate about advancing microbiome science, Dr. Morris has pioneered innovative methods for cultivating beneficial microbes and developing high-quality, life-changing products. During this episode you will learn about: How imbalances in the gut microbiome manifest in common women's health issues The fascinating connection between cortisol, stress, and the gut microbiome What "microbiome" and the broader "holobiome" are Website: alimentumlabs.com Social Media: @drshaynemorris (tik tok, instagram, facebook) @alimentumlabs (youtube)   For more on Dr. Erin: Work with Dr. Erin here: https://p.bttr.to/3E88ps4 Buy Dr. Erin's Supplements here: https://drerinellis.com/shop Get the Period Productivity Planner here:  https://www.amazon.com/dp/B0BBYBRT5Q?ref_=pe_3052080_397514860 Download the FREE Menstrual Cycle Nutrition Guide here: https://detox.drerinellis.com/ Watch The Free Video "7 Hormones Affecting Your Weight Loss Goals" here: https://weightloss.drerinellis.com/ Let's Be Friends: Follow Dr. Erin on Instagram: https://www.instagram.com/dr.erinellis/ Follow Dr. Erin on Facebook: https://www.facebook.com/drerinellisnmd Follow Dr. Erin on TikTok: https://www.tiktok.com/@dr.erinellis?lang=en Join the Fix My Period Private Facebook Group: https://www.facebook.com/groups/470429440943215 Bookmark Dr. Erin's Website: https://drerinellis.com/ Subscribe to Hope Natural Health on YouTube: https://www.youtube.com/channel/UChHYVmNEu5tKu91EATHhEiA Follow Hope Natural Health on FB: https://www.facebook.com/hopenaturalhealth Sign up for Newsletters here: https://dashboard.mailerlite.com/forms/129653/99504448452166810/share Link to Testing: https://hopenaturalhealth.wellproz.com/   #Microbiome, #GutHealth, #WomensHealth, #HormoneBalance, #Periods, #Wellness, #NaturopathicMedicine, #AdrenalHealth, #StressManagement, #Holobiome, #NaturalHealth, #GutBrainAxis, #AlimentumLabs  

With 93% of Americans now considered metabolically unhealthy, this episode is a wake-up call. The First Lady of Nutrition welcomes Ben Azadi—biohacker and author of the newly released book, Metabolic Freedom: A 30-Day Guide to Restore Your Metabolism, Heal Hormones & Burn Fat. It also explores the top hidden contributor to metabolic dysfunction—heavy metal toxicity—and why the most powerful biohack of all may be your thoughts.   In this inspiring conversation, Ben shares how he transformed his body and mind using ketosis—and why most people are doing keto all wrong. Ann Louise and Ben dive into the real keys to metabolic freedom, including how to test for ketosis (and why one method stands above the rest), the vital role of liver support, and what “metabolic flex days” can do to reset your system.   Ben also opens up about his childhood struggles with obesity and how his health journey lifted him out of depression and into clarity and confidence. According to Ben, we get thousands of chances a day to shift our body toward balance and healing. If you're looking to boost energy, burn fat, and truly feel good again, this podcast could be your roadmap to metabolic freedom.   Special Offer for our listeners: When you order Metabolic Freedom, you'll get access to a free bonus course—12 exclusive lessons on metabolism, including behind-the-scenes interviews. Visit metabolicfreedombook.com to learn more. The post Doing Keto Right: True Metabolic Freedom – Episode 194: Ben Azadi first appeared on Ann Louise Gittleman, PhD, CNS.

Episode 190: Measles BasicsFuture Dr. Kapur explained the basics of measles, including the pathophysiology, diagnosis and management of this disease. Dr. Schlaerth added information about SPPE and told interesting stories of measles. Dr. Arreaza explained some statistics and histed the episode.  Written by Ashna Kapur MS4 Ross University School of Medicine. Comments by Katherine Schlaerth, MD, and Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Introduction.According to the CDC, as of April 24, 2025, a total of 884 confirmed measles cases were reported by 30 states, including California, and notably Texas. This is already three times more cases than 2024. There are 3 confirmed deaths so far in the US. What is measles?Measles is a disease that's been around for centuries, nearly eradicated, yet still lingers in parts of the world due to declining vaccination rates. Let's refresh our knowledge about its epidemiology, clinical features, diagnosis, management, and most importantly — prevention.Definition.Measles, also known as rubeola, is an acute viral respiratory illness caused by the measles virus. It's a single-stranded, negative-sense RNA virus belonging to the Paramyxoviridae family. It's extremely contagious with a transmission rate of up to 90% among non-immune individuals when exposed to an infected person.EpidemiologyBefore the introduction of the measles vaccine in 1963, nearly every child got measles by the time they were 15 years old. With the introduction of vaccination, cases and deaths caused by measles significantly declined. For example, in 2018, over 140,000 deaths were reported in the whole world, mostly among children under the age of 5.Measles is still a common disease in many countries, including in Europe, the Middle East, Asia, and Africa. Measles outbreaks have been reported recently in the UK, Israel, India, Thailand, Vietnam, Japan, Ukraine, the Philippines, and more recently in the US. So, let's take prevention seriously to avoid the spread of this disease here at home and abroad. How do we get measles, Ashna?Mode of Transmission:● Air: Spread primarily through respiratory droplets.● Surfaces: The virus remains viable on surfaces or in the air for up to 2 hours. (so, if a person with measles was in a room and you enter the same room within 2 hours, you may still get measles)● Other people: Patients are contagious from 4 days before until 4 days after the rash appears.PathophysiologyThe measles virus first infects the respiratory epithelium, replicates, and then disseminates to the lymphatic system.It leads to transient but profound immunosuppression, which is why secondary infections are common. It affects the skin, respiratory tract, and sometimes the brain, leading to complications like pneumonia or encephalitis.Clinical PresentationThe classic presentation of measles can be remembered in three C's:● Cough● Coryza (runny nose)● ConjunctivitisCourse of Disease (3 Phases):1. Prodromal Phase (2-4 days)○ High fever (can peak at 104°F or 40°C)○ The 3 C's○ Koplik spots: Small white lesions on the buccal mucosa.2. Exanthem Phase○ Maculopapular rash begins on the face (especially around the hairline), then spreads from head to toe. The rash typically combines into 1 big mass as it spreads, and the fever often persists during the rash.3. Recovery Phase○ Rash fades in the same order it appeared.○ Patients remain at risk for complications during and after rash resolution.Complications:● Pneumonia (most common cause of death in children)● Otitis media (most common overall complication)● Encephalitis (can lead to permanent neurologic sequelae)● Subacute sclerosing panencephalitis (SSPE): A rare, fatal, degenerative CNS disease that can occur years after measles infection.High-risk groups for severe disease include:● Infants and young children● Pregnant women● Immunocompromised individualsDiagnosisClinical diagnosis is sufficient if classic symptoms are present, especially in outbreak settings.Ashna: Laboratory confirmation:● Measles-specific IgM antibodies detected by serology.● RT-PCR from nasopharyngeal, throat, or urine samples.Notify public health authorities immediately upon suspicion or diagnosis of measles to limit spread. ManagementThere is no specific antiviral treatment for measles. Management is supportive:● Hydration (by mouth and only IV in case of severe dehydration)● Antipyretics (e.g., acetaminophen) for fever● Oxygen if hypoxicVitamin A supplementation:● Recommended for all children with acute measles, particularly in areas with high vitamin A deficiency. It has shown to reduce morbidity and mortality.Hospitalization may be necessary for:● Severe respiratory compromise● Dehydration● Neurologic complicationsPrevention: We live in perilous times and vaccination is under scrutiny right now. Before the measles vaccine, about 48,000 people were hospitalized and 400–500 people died in the United States every year. Measles was declared eradicated in the US in 2000, but the vaccination coverage is no longer 95%. How do we prevent measles?Vaccination is the cornerstone of prevention.● MMR vaccine (Measles, Mumps, Rubella):○ First dose at 12-15 months of age.○ Second dose at 4-6 years of age.○ 97% effective after 2 doses.The Advisory Committee on Immunization Practices (ACIP) has noted that febrile seizures typically occur 7 to 12 days after vaccination with MMR, with an estimated incidence of 3.3 to 8.7 per 10,000 doses. The Centers for Disease Control and Prevention (CDC) states that febrile seizures following MMR vaccination are rare and not associated with any long-term effects. The risk of febrile seizures is higher when the MMR vaccine is administered as part of the combined MMRV (measles, mumps, rubella, and varicella) vaccine compared to the MMR vaccine alone.Post-exposure prophylaxis:● MMR vaccine within 72 hours of exposure (if possible).● Immunoglobulin within 6 days for high-risk individuals (e.g., infants, pregnant women, immunocompromised).Herd immunity requires at least 95% vaccination coverage to prevent outbreaks.Key Takeaways● Measles is a highly contagious viral illness that can lead to severe complications.● Diagnosis is often clinical, but lab confirmation helps with public health tracking.● Treatment is mainly supportive, with Vitamin A playing a critical role in reducing complications.● Vaccination remains the most effective tool to eliminate measles worldwide.While measles might seem like a disease of the past, it can make a dangerous comeback without continued vigilance and vaccination efforts.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Centers for Disease Control and Prevention (CDC). Measles (Rubeola), Clinical Overview, July 15, 2024. Accessed on May 1, 2025. https://www.cdc.gov/measles/hcp/clinical-overview/index.html.World Health Organization (WHO). Measles, November 14, 2024. https://www.who.int/news-room/fact-sheets/detail/measlesGans, Hayley and Yvonne A. Maldonado, Measles: Clinical manifestations, diagnosis, treatment, and prevention, UpToDate, January 15, 2025. Accessed on May 1, 2025. https://www.uptodate.com/contents/measles-clinical-manifestations-diagnosis-treatment-and-preventionTheme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

Patti Milligan – (IG: @milliganpatti, X: @pattimilligan, FB: @patti.t.milligan) PhD, RD, CNS has a Bachelor of Science in Dietetics and Consumer Sciences, Master of Science in Nutritional Biochemistry and Sports Medicine and a Doctorate in Neuroscience of Taste specializing in saliva's impact in regeneration nutrition. As a competitive athlete, and trained nutritionist, she approaches performance in a truly integrated way. She links neuroscience of taste and eating behaviors in a novel way to bring more satiety and fun of daily eating experiences for all. She combines her experience with the natural foods industry, knowledge, commitment, and enthusiasm to impact the way people experience high-performance foods and supplements to elevate their energy, brain agility resilience, and overall performance. She is also the CEO & Founder of Renewal Kit for Travelers, a great way for anyone that travels often to reduce the side effects of jet lag, brain fog, and slow digestion from excess traveling. To watch Dr. Milligan's TEDx talk ‘Your Saliva is Talking to You' - CLICK HERE     Affiliates: PAYNTR Golf Shoes - Payntr Golf delivers performance traction resulting from our shoe's ability to resist, support, & enhance – allowing golfers the capacity to leverage ground forces, control movement, and maximize speed at impact. https://payntrgolf.com/golf360 Books by Rande Somma Why Do We Call Them Leaders?: https://amzn.to/3VIhDI6 Leadersh!t: https://amzn.to/3VY4zib The Stack System is the ultimate device to use when looking to biohack your swing speed. Co-developed by ‘The Savant of Speed' – Dr. Sasho MacKenzie, and PING engineer Marty Jertsen, it is a device that every golfer can utilize to increase their swing speed. The Stack System uses AI to ensure that your development is as efficient as possible. To order The Stack you can do so on their website at www.thestacksystem.com. Be sure to use the discount code GOLF360 to receive your special discount. Sponsors: Get your 15% discount on your next order of JustThrive Probiotic at https://justthrivehealth.com/ (use code: GOLF360) Looking to play one of the best golf courses in the Hilton Head Island area? Be sure to check out Old South Golf Links and have one of your best golf experiences ever https://www.oldsouthgolf.com/  

In this episode of The Nurse Practitioner Podcast, Julia Rogers, DNP, APRN, CNS, FNP-BC, FAANP and Stephen Ferrara, DNP, FNP, FAANP, FAAN discuss AI and NP practice.

MCAS, hypermobility, neurodivergence, & dysautonomia with Dr. Laura Gouge, ND, CNSIn this episode of The Healer Revolution, I sit down with Dr. Laura Gouge, ND, CNS, a naturopathic physician and expert in mast cell activation syndrome (MCAS), POTS, ADHD, long COVID, and nervous system dysregulation. We dive deep into the connections between immune function, histamine intolerance, neurodivergence, and chronic conditions like hypermobility, dysautonomia, and anxiety.Dr. Gouge shares her personal journey with MCAS, histamine intolerance and how she helps patients reduce sensitivities, regulate their nervous system, and reclaim their energy. We discuss why so many people with ADHD and anxiety also struggle with MCAS and how understanding these links can unlock deeper healing.If you've ever felt like your symptoms are all over the place—ranging from allergies and gut issues to joint pain and brain fog and burnout—this conversation is for you!

Building on the science of the gut-brain axis, this episode focuses on actionable strategies pharmacists can use to counsel patients on mental health, gut-related medication effects, and evidence-based lifestyle interventions. From tailored counseling tips to supplement and nutrition guidance, pharmacists will learn how to support patients managing both GI and mental health symptoms. Tune in to discover how small conversations can lead to big health improvements in both gut and brain function.HOSTJoshua Davis Kinsey, PharmDVP, EducationCEimpactGUESTLara Zakaria, PharmD, MS, CNS, CDN, IFMCPOwner, FounderFoodie Farmacist LLCPharmacists, REDEEM YOUR CPE HERE!CPE is available to Health Mart franchise members onlyTo learn more about Health Mart, click here: https://join.healthmart.com/CPE INFORMATION Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Identify evidence-based strategies pharmacists can use to support patients with gastrointestinal issues linked to mental health conditions.2. Explain how lifestyle, diet, and complementary supplements influence the gut-brain connection to support patient care.0.05 CEU/0.5 HrUAN: 0107-0000-25-154-H01-PInitial release date: 5/5/2025Expiration date: 5/5/2026Additional CPE details can be found here.

Building on the science of the gut-brain axis, this episode focuses on actionable strategies pharmacists can use to counsel patients on mental health, gut-related medication effects, and evidence-based lifestyle interventions. From tailored counseling tips to supplement and nutrition guidance, pharmacists will learn how to support patients managing both GI and mental health symptoms. Tune in to discover how small conversations can lead to big health improvements in both gut and brain function.HOSTJoshua Davis Kinsey, PharmDVP, EducationCEimpactGUESTLara Zakaria, PharmD, MS, CNS, CDN, IFMCPOwner, FounderFoodie Farmacist LLCPharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE INFORMATIONLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Identify evidence-based strategies pharmacists can use to support patients with gastrointestinal issues linked to mental health conditions.2. Explain how lifestyle, diet, and complementary supplements influence the gut-brain connection to support patient care.0.05 CEU/0.5 HrUAN: 0107-0000-24-154-H01-PInitial release date: 5/5/2025Expiration date: 5/5/2026Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

Lorlatinib is reshaping first-line treatment for ALK-positive NSCLC—but its distinct side effect profile demands proactive, personalized management. In this episode,  Stefanie Houseknecht, PharmD, BCOP (Johns Hopkins Medicine) and Monica Chintapenta, PharmD, BCOP (Parkland Health)share how they're navigating real-world use of lorlatinib, from interpreting long-term data to counseling patients through CNS effects, weight gain, and metabolic challenges.Highlights:Why lorlatinib is gaining traction in first-line ALK+ NSCLCWhat the long-term CROWN data really means for patient outcomesHow to handle tricky side effects like cognitive changes, weight gain, and hyperlipidemiaReal-world tips for patient counseling and supporting adherenceThe importance of catching drug interactions and staying ahead on labsHow pharmacists are shaping care across the oncology teamBonus: Hear how our guests find balance beyond the clinic, whether in the garden or on the Boston marathon course. About Our Guests:Monica completed her Doctor of Pharmacy at Texas Tech University Health Sciences Center and went on to complete PGY-1 and PGY-2 residencies at Tufts Medical Center and Froedtert & the Medical College of Wisconsin, respectively. At Parkland, she supports outpatient hematology/oncology care and leads quality initiatives.   Stefanie earned her PharmD from the University of the Pacific, followed by PGY-1 and PGY-2 residencies at Palomar Medical Center and the University of California-San Diego. Her work focuses on thoracic malignancies, access to oral targeted therapies, and patient outcomes. She is active in the International Association for the Study of Lung Cancer and serves as a preceptor to pharmacy trainees across the Mid-Atlantic.  

In this Thursday episode of Tom the Trainer's Fitness Podcast, I go deep on some of the most pressing questions from my Facebook group, Tom the Trainer's Tribe.This episode tackles big topics like: Can you get bodybuilder-level shredded in your 70s without a gym? How does aging impact hormones, recovery, and realistic expectations? I share brutally honest but hopeful insights, covering everything from training intensity and testosterone therapy to skin elasticity and smart goal setting for older adults.I also dive into tendon pain solutions for biceps and triceps, with actionable advice on biomechanics, smart rest, and why your grip angle might be wrecking your joints. And if you're an active person trying to balance sports (like walking 7 miles, playing golf!) with muscle-building goals, I break down how to intuitively manage your training volume, CNS fatigue, and recovery using real-life examples.With a blend of practical science, personal stories, and unfiltered wisdom, this episode is a goldmine for anyone in their 40s, 50s, 60s, or even 70s, trying to get leaner, stronger, and smarter about fitness.Want to transform your body in the next 12 weeks? Join Tom The Trainer's Tribe, and message me the word “coaching” on Instagram at Tomthetrainerfitness or Facebook at Tom Trainer Mouland!Have the best day ever! Hosted on Acast. See acast.com/privacy for more information.

Emma Wille and Summer Colling discuss the 2025 American Academy of Neurology (AAN) conference with CNS and I&I analysts Wen-Yu Huang, Joseph Jacob and Istafa Armughan.

This is the second episode of a two-part series on the HER2 diagnostic and treatment landscape in non-small cell lung cancer (NSCLC), hosted by the Oncology Brothers, Drs Rohit and Rahul Gosain.      In this episode, Dr Isabel Preeshagul and Dr Eric Singhi provide the benefit of their experience when discussing how to approach different treatment scenarios in HER2-mutant NSCLC.   The conversation unfolds to cover: • Ways to distinguish HER2 alterations from other alterations on biomarker reports  • The latest efficacy and safety data of currently approved and emerging treatments for HER2-altered NSCLC   • The potential CNS activity of these treatments in patients with HER2-mutated NSCLC  • How the treatment pathway may look in the near future      Clinical takeaways • In NSCLC, HER2-positivity includes mutations, amplifications and overexpression. It's important to distinguish HER2 alterations from EGFR mutations, particularly exon 20 insertions, when interpreting next-generation sequencing (NGS) results  • Trastuzumab Deruxtecan (T-DXd) is currently the only approved targeted agent for HER2-altered NSCLC in the 2nd-line setting. It shows promising efficacy, especially in HER2-mutant cases, but has limited brain penetration and is associated with notable side effects, including pneumonitis, which requires close monitoring  • Emerging TKIs, such as zongertinib, BAY 2927088 (sevabertinib), and NVL-330, target HER2-mutations and have shown high response rates and CNS activity in early studies, without ILD/pneumonitis. These treatments come with unique side effects like diarrhoea and rash, which can be managed with supportive care  • CNS metastases are common, with up to 30% of HER2-altered NSCLC patients presenting with or quickly developing CNS metastases. Current large molecule therapies (like T-DXd) have limited brain penetration, making small-molecule TKIs, like zongertinib, BAY 2927088 (sevabertinib), and NVL-330, promising for their potential CNS activity • Current standard 1st-line care for HER2-mutant NSCLC remains platinum-based chemotherapy ± immunotherapy. Targeted agents (like T-DXd) are generally reserved for 2nd-line use, but ongoing trials are evaluating the move toward frontline therapy Follow us on social media: •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ Don't forget to subscribe for the next episode

The gut and brain are in constant conversation, influencing everything from mood and motivation to digestion and hormonal health. In this episode, we unpack the fundamentals of the gut-brain axis, including the role of the microbiome, common medications that impact gut health, and how those changes can ripple into mental well-being. Tune in to build your foundational knowledge and start recognizing how pharmacy practice intersects with the gut-brain connection.HOSTJoshua Davis Kinsey, PharmDVP, EducationCEimpactGUESTLara Zakaria, PharmD, MS, CNS, CDN, IFMCPOwner, FounderFoodie Farmacist LLCPharmacists, REDEEM YOUR CPE HERE!CPE is available to Health Mart franchise members onlyTo learn more about Health Mart, click here: https://join.healthmart.com/CPE INFORMATION Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Explain the physiological connection between the gut and brain, including the role of the microbiome in mental and neurological health.2. Describe how some drugs can influence the composition and function of the gut microbiome.0.05 CEU/0.5 HrUAN: 0107-0000-25-153-H01-PInitial release date: 4/28/2025Expiration date: 4/28/2026Additional CPE details can be found here.

The gut and brain are in constant conversation, influencing everything from mood and motivation to digestion and hormonal health. In this episode, we unpack the fundamentals of the gut-brain axis, including the role of the microbiome, common medications that impact gut health, and how those changes can ripple into mental well-being. Tune in to build your foundational knowledge and start recognizing how pharmacy practice intersects with the gut-brain connection.HOSTJoshua Davis Kinsey, PharmDVP, EducationCEimpactGUESTLara Zakaria, PharmD, MS, CNS, CDN, IFMCPOwner, FounderFoodie Farmacist LLCPharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE INFORMATIONLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Explain the physiological connection between the gut and brain, including the role of the microbiome in mental and neurological health.2. Describe how some drugs can influence the composition and function of the gut microbiome.0.05 CEU/0.5 HrUAN: 0107-0000-25-153-H01-PInitial release date: 4/28/2025Expiration date: 4/28/2026Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

Join The First Lady of Nutrition as she engages in a fascinating conversation with Elwin Robinson, the visionary founder of Genetic Insights—a next-level DNA analysis company that's lightyears ahead of the rest. If you've ever felt caught in a cycle of symptoms without real solutions, this eye-opening interview will shift your entire perspective on health and healing. Elwin reveals how his team of scientists and AI engineers analyzes over 200 million genetic variations, delivering 500+ in-depth reports covering everything from hormone health and food intolerances to nutrient deficiencies and lab markers in one of the most comprehensive, inexpensive DNA tests on the market today. After interviewing Elwin, Ann Louise took the test herself—and what impressed her most was its ability to pinpoint which nutrients an individual is genetically most deficient in. That is how she knew to take orthomolecular doses of lysine and glycine—and how she was introduced to time-released T3 to support her low thyroid. You'll discover how small, targeted changes based on your unique DNA can lead to big breakthroughs in your health. Elwin shares compelling real-life success stories that show just how powerful it can be to address even the most basic nutritional gaps. This is the future of personalized wellness—don't miss it! As a special gift to our listeners, get 25% off Elwin's DNA testing with code FLN25 at checkout: https://geneticinsights.co/geneticinsightslimitless/gscpage.html The post The Most Comprehensive DNA Analysis You'll Ever Uncover – Episode 193: Elwin Robinson first appeared on Ann Louise Gittleman, PhD, CNS.

Are you navigating perimenopause or menopause while also managing chronic health conditions? Or perhaps perimenopause has triggered an underlying, previously dormant issue? Traditional healthcare may not be enough to combat the symptoms, but do not fear! Today's guest is here to teach us how your nervous system, immune system, and hormones can all work together to support healing and longevity. This week, host Jenn Trepeck is joined by Dr. Jessica Drummond, Founder and CEO of The Integrative Women's Health Institute. Together, they explore how seemingly “silent” chronic conditions like endometriosis, pelvic pain, autoimmune disorders or even long covid, can complicate menopause—and what you can do about it. Dr. Drummond shares her insights on calming the nervous system, building metabolic health through nutrient-dense habits, and using tools like heart rate variability (HRV) to guide recovery. The Salad With a Side of Fries podcast is hosted by Jenn Trepeck, who discusses wellness and weight loss for real life, clearing up the myths, misinformation, bad science & marketing surrounding our nutrition knowledge and the food industry. Let's dive into wellness and weight loss for real life, including drinking, eating out, and skipping the grocery store. IN THIS EPISODE: (00:00) The impact of menopause on silent chronic conditions(05:44) Dr. Jessica Drummond reflects on her professional journey in the chronic condition space(11:11) Common underlying chronic conditions affecting menopause(16:08) Discussion of the silent underlying conditions that can manifest later in life(25:43) Calming the nervous system to heal in a consistent way(30:50) The importance of your metabolic health in the form of nutrient-dense food, strength training, walking, hydration and circadian rhythm(32:09) Discussion of heart rate variability, recovery, and developing the art of sitting quietly(41:36) The importance of working with a health coach to plan for the future of your healthKEY TAKEAWAYS:Menopause and perimenopause symptoms can be overwhelming on their own. Still, when layered on top of chronic conditions like endometriosis, pelvic pain, autoimmune disorders, or post-viral syndromes (e.g., long COVID), it creates a compounded health challenge. Traditional training often overlooks the role of nutrition, nervous system regulation, and lifestyle in healing. Chronic conditions—especially during perimenopause—require a personalized, holistic strategy.Healing during menopause doesn't require drastic changes—small, consistent steps matter most. Start where it feels easiest, like mindfulness, nutrition, or gentle movement. Recovery and nervous system regulation are just as important as action. Tools like heart rate variability (HRV) can help track progress, showing that true resilience comes from balancing effort with rest.Integrating the nervous, immune, and hormone systems is the key to living a longer, more active, healthier life. When these systems are balanced and working together, they support overall well-being and longevity.QUOTES:         (10:04) “In my traditional physical therapy training, nutrition was not emphasized as a healing tool. It was more like you needed adequate nutrients to perform certain physical activities, but we didn't think about it from an anti-inflammatory standpoint.” - Dr. Jessica Drummond(13:59) “Research shows us that acute illnesses like infections trigger chronic diseases.” - Dr. Jessica Drummond(22:36) “It's exposing these underlying things that have been lying dormant, that we just brushed aside or pushed through because they weren't really standing in the way of us doing the things that we wanted to do.”  - Jenn Trepeck(40:19) “I think we make these plans expecting perfection, planning for this optimal, ideal day that never happens. So put these things in place so they happen even on the days where we don't feel a hundred percent, even on the days where nothing goes as planned.” - Jenn TrepeckRESOURCES:Become A Member of Salad with a Side of FriesJenn's Free Menu PlanA Salad With a Side of FriesA Salad With A Side Of Fries MerchA Salad With a Side of Fries InstagramUse Your Heart Rate Monitor to Improve Your Health                GUEST RESOURCES:The Integrative Women's Health InstituteIntegrative Women's Health  - Podcast Integrative Women's Health - PubMedInnovative Approaches to Chronic Pain with The Anodunos Method TeamGUEST BIOGRAPHY:Dr. Jessica Drummond, DCN, CNS, PT, NBC-HWC, is a leading expert in women's health and the Founder and CEO of The Integrative Women's Health Institute. With 25 years of clinical experience, in her MenoChronic Program, she specializes in supporting women ages 35-55 through the perimenopause and menopause transitions who struggle with underlying chronic conditions such as pelvic pain, endometriosis, post-viral syndromes (such as long covid), and autoimmune issues, using health coaching, integrative, and functional medicine. She is a licensed clinical nutritionist, physical therapist, and board-certified Women's Health Coach. Dr. Drummond is the best-selling author of Outsmart Endometriosis and Clinician to Coach: Secrets to Building Your Successful Health Coach Practice, offering practical strategies for health and wellness practitioners.

Simon Green isn't the first country bloke to put off going to the Doctor. But when an extremely rare and sinister tumour began snaking its way down his spine, time was not on the father of three's side. In less than four weeks, his symptoms morphed from mild discomfort to nerve tingling to full-blown paralysis of his lower body. With Simon's condition quickly deteriorating, his Doctors arranged an emergency RFDS evacuation to Newcastle. Later, specialists from around the world would consult on the best way to salvage his spinal cord and save Simon's life - after diagnosing him with a cancer of the Central Nervous System that accounts for less than 2% of all brain and other CNS tumors.***Thanks so much for listening to this episode of the Flying Doctor Podcast. It is lovely to have you along on the journey with us.There has been some wonderful feedback from listeners about our podcast and the incredible people we have interviewed. Word of mouth is always the best promotion for a podcast – so if you enjoy this podcast, or a specific story, please share with family and friends. Reviews and ratings help our podcast to be found by others, so if you can take the time to do that it would be appreciated. You can also send feedback, questions or comments through to podcast@rfds.org.au. We'd also love you to become part of the Flying Doctor Podcast Facebook group, where passionate listeners and incredible outback communities come together. Hosted on Acast. See acast.com/privacy for more information.

This episode of The Dr. Terri Show features guest Elizabeth DiMeo, MS, CNS, LDN, and challenges the overemphasis on vaccine hysteria, arguing that children's diets and overall nutrition deserve far greater public health attention. The hosts explore the impact of processed foods and sugar on children, the crucial role of prenatal and early childhood nutrition (including a critique of infant formula), the link between gut health and autism, and the stark contrast between America's food culture and healthier global models. -- The Dr. Terri Show is presented by Evexias Health Solutions. For more, visit: https://www.evexias.com Connect more with Dr. Terri:

Join The First Lady of Nutrition as she sits down with Leo Tonkin, one of the nation's leading voices on the science and benefits of salt therapy—also known as halotherapy. From its origins in the healing salt mines of Eastern Europe to its modern-day use in thousands of wellness centers across the U.S., this ancient remedy is making a powerful comeback. Ann Louise and Leo get right to the heart of the matter, exploring how dry salt therapy—more absorbent and potent than ocean air or nebulizers—can help improve respiratory health, skin conditions, and immunity. Safe for daily use (even for infants), it has become a go-to for athletes looking to boost lung function and for anyone dealing with asthma, COPD, eczema, acne, or allergies. Tune in to learn the truth about Himalayan salt lamps, what kind of salt is really therapeutic, and how you can create your own pop-up salt booth at home. As Leo explains, breathing clean air isn't just refreshing, it could be the single most important marker of longevity and quality of life. To find a salt therapy location near you, visit www.salttherapyassociation.org/ and check out Leo's innovations at https://salttherapyhome.com/. The post Could Salt Be The Secret to Better Breathing? – Episode 192: Leo Tonkin first appeared on Ann Louise Gittleman, PhD, CNS.

Send us a textCan you heal your skin from the inside out? Is your daily dairy intake sabotaging your skin's clarity? Dive into the powerful connection between nutrition, the gut, and our largest organ, the skin. This episode promises to uncover the intricate relationships and the latest approaches to addressing common skin issues.Join Dr. Emmie Brown, ND, and co-host Melissa Gentile, INHC, as they welcome Dr. Dana Filatova, DCN, CNS, LDN, a doctor of clinical nutrition, to explore the dynamic interplay between gut health and skin conditions. Dr. Filatova unveils her journey with acne and how it ignited her passion for nutrition. She shares the intricate connections of the gut-skin axis, emphasizing the role of the microbiome and how inflammation in the gut can reflect on the skin's health, influencing conditions like acne, eczema, and rosacea. From food sensitivities to lifestyle changes, Dr. Filatova offers insights into holistic approaches to skincare. And for all the dog lovers out there, we even touch on the shared microbiomes between humans and dogs!Key Takeaways from Today's Episode:

Optic neuropathies encompass all congenital or acquired conditions affecting the optic nerve and are often a harbinger of systemic and central nervous system disorders. A systematic approach to identifying the clinical manifestations of specific optic neuropathies is imperative for directing diagnostic assessments, formulating tailored treatment regimens, and identifying broader central nervous system and systemic disorders. In this episode, Gordon Smith, MD, FAAN speaks with Lindsey De Lott, MD, MS, author of the article “Optic Neuropathies” in the Continuum® April 2025 Neuro-ophthalmology issue. Dr. Smith is a Continuum® Audio interviewer and a professor and chair of neurology at Kenneth and Dianne Wright Distinguished Chair in Clinical and Translational Research at Virginia Commonwealth University in Richmond, Virginia. Dr. De Lott is an assistant professor of neurology and ophthalmology at the University of Michigan in Ann Arbor, Michigan. Additional Resources Read the article: Optic Neuropathies Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @gordonsmithMD Guest: @lindseydelott Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Smith: Hello, this is Dr Gordon Smith. Today I'm interviewing Dr Lindsey De Lott about her article on optic neuropathies, which appears in the April 2025 Continuum issue on neuro-ophthalmology. Lindsey, welcome to the podcast, and perhaps you can introduce yourself to our audience. Dr De Lott: Thank you, Dr Smith. My name is Lindsey De Lott and I am a neurologist and a neuro-ophthalmologist at the University of Michigan. I also serve as the section lead for the Division of Neuro-Ophthalmology, which is actually part of the ophthalmology department rather than the neurology department. And I spend a good portion of my time as a researcher in health services research, and that's now about 60% of my practice or so. Dr Smith: I'm super excited to spend some time talking with you. One, I'm a Michigan person. As we were chatting before this, I trained with Wayne Cornblath and John Trobe, and it's great to have you. I wonder if we maybe can begin- and by the way, your article is outstanding. It is such a huge topic and it was actually really fun to read, so I encourage our listeners to check it out. But you begin by talking about misdiagnosis as being a common problem in this patient population. I wonder if you can talk through why that is and if you have any pearls or pitfalls in avoiding it? Dr De Lott: Yeah, I think there's been a lot of great research looking at misdiagnosis in specific types of optic neuropathies; in particular, compressive optic neuropathies and optic neuritis. A lot of that work has come out of the group at Emory and the group at Washington University. But a lot of neuro-ophthalmologists across the country really contributed to those data. And one of the statistics that always strikes me is that, you know, for example, in patients with optic nerve sheath meningiomas, something like 70% of them are actually misdiagnosed. And a lot of those errors in diagnosis, whether it's for compressive optic neuropathy or some other type of optic neuropathy, really comes down to the way that physicians are really incorporating elements of the history in the physical. For example, in optic neuritis, we know that physicians tend to anchor pretty heavily on pain in general. And that often tends to lead them astray when optic neuritis was never the diagnosis to begin with. So, it's really overindexing on certain things and not paying attention to other features of the physical exam; for example, say presence of an afferent pupillary defect. So, I think it just really highlights the need to have a really relatively structured approach to patients that you think have an optic neuropathy when you're trying to sort of plan your diagnostic testing and your treatment. Dr Smith: I do maybe five or six weeks on our hospital service each year, and I don't know if it's just a Richmond thing, but there's always at least two people in my week who come in with an optic neuropathy or acute vision loss. How common is this in medical practice? Or neurologic practice, I should say? Dr De Lott: Optic neuropathies themselves… if you look across, unfortunately we don't have any great data that puts together all optic neuropathies and gives us an actual sort of prevalence estimate or an incidence estimate from year to year. We do have some of those data for specific types of optic neuropathies like optic neuritis and NAION, and you're probably looking around five-ish per one hundred thousand. So, these aren't that common, but at the same time they do get funneled to- often to emergency rooms and to neurologists from our ophthalmology colleagues and optometry colleagues in particular. Dr Smith: So, one other question I had before kind of diving into the topic at hand is how facile neurologists need to be in recognizing other causes of acute visual loss. I mean, we see acute visual loss as neurologists, we think optic neuropathy, right? Optic neuritis is sort of the go-to in a younger patient, and NAION in someone older. But what do neurologists need to know about other ophthalmologic causes? So, glaucoma or acute retinal disorders, for instance? Dr De Lott: Yeah, I think it's really important that neurologists are able to distinguish optic neuropathies from other causes of vision loss. And so, I would really encourage the listeners to take a look at the excellent article by Nancy Newman about vision loss in this issue where she really kind of breaks it down into vision loss that is acute and chronic and how you really think through distinguishing optic neuropathies from other causes of vision loss. But it is really important. For example, a patient with a central retinal artery occlusion may potentially be eligible for treatments. And that's very different from a patient with optic neuritis and acute vision loss. So, we want to be able to distinguish these things.  Dr Smith: So maybe we can pivot to that a little bit. Just for our listeners, our focus today is going to be on- not so much on optic neuritis, although obviously we need to talk a little bit about how we differentiate optic neuritis from non-neuritis optic neuropathies. It seems like the two most common situations we encounter are ischemic optic neuropathies and optic neuritis. Maybe you can talk a little bit about how you distinguish these two? I mean, some of it's age, some of it's risk factors, some of it's exam. What's the framework, of let's say, a fifty-year-old person comes into the emergency room with acute vision loss and you're worried about an optic neuropathy? Dr De Lott: The first step whenever you are considering an optic neuropathy is just making sure that the features are present. I think, really going back to your earlier question, making sure that the patient has the features of an optic neuropathy that we expect. So, it's not only vision loss, but it's also the presence of an apparent pupillary defect in a patient with a unilateral optic neuropathy. In a person who has a bilateral optic neuropathy, that apparent pupillary defect may not be present because it is relative. So, you really would have to have asymmetric vision loss between the two eyes. They should also have impairment of their color vision, and they're probably going to have some kind of visual field defect, whether that's central scotoma or an arcuate scotoma or an altitudinal defect that really respects the horizontal meridian. So, you want to make sure that, first and foremost, you've got a patient that really meets most of those- most of those features. And then from there, we're looking at the other features on their history. How acute is the onset of the vision loss? What is the progression over time? Is there pain associated or not associated with the vision loss? What other medical issues does the patient have? And you know, one of the things you already brought up, for example, is, what's the age of the patient? So, I'm going to be much more hesitant to make a diagnosis of optic neuritis in a much older patient or a diagnosis on the other side, of ischemic optic neuropathy, in a much younger patient, unless they have really clear features that push me in that direction. Dr Smith: I wonder if maybe you could talk a little bit about features that would push you away from optic neuritis, because, I mean, people who are over fifty do get optic neuritis- Dr De Lott: They do. Dr Smith: -and people who get ischemic optic neuropathies who are younger. So, what features would push you away from optic neuritis and towards… let's be broad, just a different type of optic neuropathy? Dr De Lott: Sure. We know that most patients with optic neuritis do have pain, but that pain is accompanied---within a few days, typically---with vision loss. So, pain alone going on for a number of days without any visual symptoms or any of those other things I listed, like the afferent papillary defect, the visual field defect, would push me away from optic neuritis. But in general, yes, most optic neuritis is indeed painful. So, the presence of optic disc edema is unfortunately one of those things that an optic neuritis may be present, may not be present, but in somebody with ischemia that is anterior---and that's the most common type of ischemic optic neuropathy, would be anterior ischemic optic neuropathy---they have to have optic disc edema for us to be able to make that diagnosis, and that is a diagnosis of NAION, or nonarteritic ischemic optic neuropathy. An APD in this case, again, that's just a feature of an optic neuropathy. It doesn't really help you to distinguish, individual field defects are going to be relatively similar between them. So then in patients, I'm also looking, like I said, at their history. So, in a patient where I'm entertaining a diagnosis of ischemic optic neuropathy, I want to make sure that they have vascular risk factors or that I'm actually doing things like measuring their blood pressure in the office if they haven't seen a physician recently or checking a lipid panel, hemoglobin A1c, those kinds of things, to look for vascular risk factors. One of the other features on exam that might push me more- again, in a patient with ischemic optic neuropathy, where it might suggest ischemia over optic neuritis, would be some other features on exam like a crowded optic disc that we sometimes will see in patients with ischemic optic neuropathy. I feel like that was a bit of a convoluted answer. Dr Smith: I thought that was a great answer. And when you say crowded optic disc, that's the- is that the “disc at risk”? Dr De Lott: That is the “disk at risk,” yes. So, crowded optic disk is really a disk that is smaller than what we see in the average population, and the average cup to disk ratio is 0.3. So, I think that's where 30% of the disk should be. So, this extra wiggle room, as I sometimes will explain to my patients. Dr Smith: And then, I wonder if you could talk a little bit about more- just more about exam, right? You raised the importance of recognizing optic disc edema. Are there aspects of that disc edema that really steer you away from optic neuritis and towards ischemia-like hemorrhages or whatnot? And then a similar question about the importance of careful visual field testing? Dr De Lott: So, on the whole, optic disc edema is optic disc edema. And you can have very severe optic neuritis with hemorrhages, cotton wool spots, which is essentially just an infarction of the retinal nerve fiber layer either overlying the disc or other parts of the retina. And ischemia, you can have some of the same features. In patients who have giant cell arteritis, which is just one form of anterior ischemic optic neuropathy, patients can have a pallid optic disc edema where the optic disc is swollen and white-looking. But on the whole, swelling is swelling. So, I would caution anyone against using the features of the optic nerve swelling to make any type of, sort of, definitive kind of diagnosis. It's worth keeping in mind, but I just- I would caution against using specific features, optic nerve swelling. And then for visual field testing, there are certain patterns that sometimes can be helpful. I think as I mentioned earlier, in patients with ischemic optic neuropathy, we'll often see an altitudinal defect where either the top half or, more commonly, the bottom half of the vision is lost. And that vision loss in the field corresponds to the area of swelling on the disk, which is really rewarding when you're actually able to see sectoral swelling of the disk. So, say the top half of the disk is swollen and you see a really dense inferior defect. And other types of optic neuropathy such as hereditary optic neuropathies, toxic and nutritional optic neuropathies, they often cause more central field loss. And in patients who have optic neuropathies from elevated intracranial pressure, so papilladema, those folks often have more subtle visual field loss in an arcuate pattern. And it's only once the optic nerves have sustained a pretty significant injury that you start to see other patterns of field loss and actual decline in visual acuity in those patients. I do think a detailed visual field assessment can often be pretty helpful as an adjunct to the rest of the exam. Dr Smith: So, we haven't talked a lot about neuroimaging, and obviously, neuroimaging is really important in patients who have optic neuritis. But how about an older patient in whom you suspect ischemic optic neuropathy? Do those patients all need a MRI scan? And if so, is it orbits and brain? How do you- how do you protocol it? Dr De Lott: You're asking such a good question, totally controversial in in some ways. And so, in patients with ischemic optic neuropathy, if you are confident in your diagnosis: the patient is over the age of fifty, they have all the vascular, you know, they have vascular risk factors. And those vascular risk factors are things like diabetes, hypertension, high blood pressure, hyperlipidemia, obstructive sleep apnea. They have a “disc at risk” in the fellow eye. They don't have pain, they don't have a cancer history. Then doing an MRI of the orbits is probably not necessary to rule out another cause. But if you aren't confident that you have all of those features, then you should absolutely do an MRI of the orbit. The MRI of the brain probably doesn't provide you with much additional information. However, if you are trying to distinguish between an ischemic optic neuropathy and, say, maybe an optic neuritis, in those patients we do recommend MRI orbits and brain imaging because the brain does provide additional information about other CNS demyelinating disorders that might be actually the cause of a patient's optic neuritis. Dr Smith: I wonder if you could talk a little bit about posterior ischemic optic neuropathy. That's much less common, and you mentioned earlier that those patients don't have optic disk edema. So, if there's a patient who has vision loss that- in a similar sort of clinical scenario that you talked about, how do you approach that and under what circumstances do we see patients who have posterior ischemic optic neuropathy? Dr De Lott: So, you're going to most often see patients with posterior ischemic optic neuropathy who, for example, have undergone a recent surgery. These are often associated with things like spinal surgeries, cardiac surgeries. And there are a number of risk factors that are associated with it. Things like blood pressure, drain surgery, the amount of blood loss, positioning of patient. And this is something that the surgeons and anesthesiologists are very sensitive to at this point in time, and many patients are often- this can be part of the normal informed consent process at this point in time since this is something that is well-recognized for specific surgeries. In those patients, though… again, unless you're really certain, for example, maybe the inpatient neurology attending and you've been asked to consult on a patient and it's very clear that they went into surgery normal, they came out of surgery with vision loss, and all the rest of the features really seem to be present. I would recommend that in those cases you think about orbital imaging, making sure you're not missing anything else. Again, unless all of the features really are present- and I think that's one of the themes, definitely, throughout this article, is really the importance of neuroimaging in helping us to distinguish between different types of optic neuropathy. Dr Smith: Yeah, I think one of the things that Eric Eggenberger talks about in his article is the need to use precise nomenclature too, which I plan on talking to him about. But I think having this very structured approach- and your article does it very well, I'll tell our listeners who haven't seen it there's a series of really great tables in the article that outline a lot of these. I wonder, Lindsey, if we can switch to talk about arteritic optic neuropathy. Is that okay? Dr De Lott: Sure. Yeah, absolutely. Dr Smith: How do you sort that out in an older patient who comes in with an ischemic optic neuropathy? Dr De Lott: Yeah. In patients who are over the age of fifty with an ischemic optic neuropathy, we always need to be thinking about giant cell arteritis. It is really a diagnosis we cannot afford to miss. If we do miss it, unfortunately, patients are likely to lose vision in their fellow eye about 1/3 to 1/2 the time. So, it is really one of those emergencies in neuro-ophthalmology and neurology. And so you want to do a thorough review systems for giant cell arteritis symptoms, things like headache, jaw claudication, myalgias, unintentional weight loss, fevers, things of that nature. You also want to check their inflammatory markers to look for evidence of an elevated ESR, elevated C-reactive protein. And then on exam, what you're going to find is that it can cause an anterior ischemic optic neuropathy, as I mentioned earlier. It can cause palette optic disc swelling. But giant cell arteritis can also cause posterior ischemic optic neuropathy. And so, it can be present without any swelling of the optic disc. And in fact, you know, you mentioned one of my mentors, John Trobe, who used to say that in a patient where you're entertaining the idea of posterior ischemic optic neuropathy, who is over the age of fifty with no optic disc swelling, you should be thinking about number one, giant cell arteritis; number two, giant cell arteritis; number three, giant cell arteritis. And so, I think that is a real take-home point is making sure that you're thinking of this diagnosis often in our patients who are over the age of fifty, have to rule it out. Dr Smith: I'll ask maybe a simple question. And presumably just about everyone who you see with a presumed ischemic optic neuropathy, even if they don't have clinical features, you at least check a sed rate. Is that true? Dr De Lott: I do. So, I do routinely check sedimentation rate and C-reactive protein. So, you need to check both. And the reason is that there are some patients who have a positive C-reactive protein but a normal sedimentation rate, so. And vice versa, although that is less common. And so both need to be checked. One other lab that sometimes can be helpful is looking at their CBC. You'll often find these patients with giant cell arteritis have elevated platelet counts. And if you can trend them over time, if you happen to have a patient that's had multiple, you'll see it sort of increasing over time. Dr Smith: I'm just thinking about how you sort things out in the middle, right? I mean, so that not all patients with GCF, sky-high sed rate and CRP…. And I'm just thinking of Dr Trobe's wisdom. So, when you're in an uncertain situation, presumably you go ahead and treat with steroids and move to biopsy. Maybe you can talk a bit about that pathway? Dr De Lott: Yeah, sure. Dr Smith: What's the definitive diagnostic process? Do you- for instance, the sed rate is sky-high, do you still get a biopsy? Dr De Lott: Yes. So, biopsy is still our gold-standard diagnosis here in the United States. I will say that is not the case in all parts of the world. In fact, many parts of Europe are moving toward using other ancillary tests in combination with labs and exam, the history, to make a definitive diagnosis of giant cell arteritis. And those tests are things like temporal artery ultrasound. We also, even though we call it temporal artery ultrasound, we actually need to image not only the temporal arteries but also the axillary arteries. The sensitivity and specificity is actually greater in those cases. And then there's high-resolution imaging of the vessels and the- both the intracranial and extracranial distributions. And both of those have shown some promise in their predictive values of patients actually having giant cell arteritis. One caution I would give to our listeners, though, is that, you know, currently in the US, temporal artery biopsy is still the gold standard. And reading the ultrasounds and the MRIs takes a really experienced radiologist. So, unless you really know the diagnostic accuracy at your institution, again, temporal artery biopsy remains the gold standard here. So, when you are considering giant cell arteritis, start the patient on steroids and- that's high dose, high dose steroids. In patients with vision loss, we use high dose intravenous methylprednisolone and then go ahead and get the biopsy. Dr Smith: Super helpful. And are there other treatments, other than steroids? Maybe how long do you keep people on steroids? And let's say you've got a patient who's, you know, diabetic or has other factors that make you want to avoid the course of steroids. Are there other options available? Dr De Lott: So, in the acute phase steroids are the only option. There is no other option. However, long term, yes, we do pretty quickly put patients on tocilizumab, which is really our first-line treatment. And I do that in conjunction with our rheumatology colleagues, who are incredibly helpful in managing and monitoring the tocilizumab for our patients. But when you're seeing the patients, you know, whether it's in the emergency room or in the hospital, those patients need steroids immediately. There are other steroid-sparing agents that have been tried, but the efficacy is not as good as tocilizumab. So, the American College of Rheumatology is really recommending tocilizumab as our first line steroid-sparing agent at this point. Dr Smith: Outstanding. So again, I will refer our listeners to your article. It's just chock-full of great stuff. This has been a great conversation. Thank you so much for joining me today. Dr De Lott: Thank you, Dr Smith. I really appreciate it.  Dr Smith: The pleasure has been all mine, and I know our listeners will be enjoying this as well. Again, today I've been interviewing Dr Lindsey De Lott about her article on optic neuropathies, which appears in the most recent issue of Continuum on neuro-ophthalmology. Be sure to check out Continuum Audio episodes from this and other issues. I already mentioned Dr Eggenberger and I will be talking about optic neuritis, which will be a great companion to this discussion. Listeners, thank you for joining us today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

Send your questions or provocations to Adam or Budi here!In this episode, Budi sits down with Wellness Practitioner, Charlene Marie Muhammad to talk about her extensive career in the arts and as a yoga teacher.Charlene Marie Muhammad (MS, CNS, LD, E-RYT500, C-IAYT), a wellness practitioner, practicing yoga for over 30 years is a E-RYT500 yoga teacher. Since 2006, Charlene teaches weekly yoga classes for communities of color and facilitates YTT 200- and 300-hour core requirements workshops for YTT schools around the United States. She was the yoga interventionist for the National Institutes of Health's National Institute of Arthritis and Musculoskeletal and Skin Disease clinical study Yoga as Self-Care for Arthritis in Minority Communities (NCT01617421). The study assessed the feasibility and acceptability of providing yoga to an urban, minority population with arthritis. Charlene has presented workshops and lectures at local, regional, national, and most recently international venues such as the keynote: Health equity and access to care: yoga's important role in healing for the Global Yoga Therapy Day Conference (2021). Charlene holds a Master of Science Degree in Herbal Medicine from Maryland University of Integrative Health (MUIH) and is a licensed dietitian and certified yoga therapist. She is a member of the Black Yoga Teachers Alliance (BYTA) Board of Directors, served as chair for the Diversity, Equity, and Inclusion Task Force for the International Association of Yoga Therapists (IAYT), and provides mentorship for the Yoga for Arthritis teacher certification program and the Certified Nutrition Specialist certification program. Mentioned in this episodeUrban Herbalist  Support the showIf you enjoyed this week´s podcast, please leave a review on Apple Podcasts. To submit a question: Voice- http://www.speakpipe.com/theatreofothers Email- podcast@theatreofothers.com Show Credits Co-Hosts: Adam Marple & Budi MillerProducer: Jack BurmeisterMusic: (Intro) Jack Burmeister, (Outro) https://www.purple-planet.comAdditional compositions by @jack_burmeister

Featuring an interview with Dr Justin F Gainor, including the following topics: Duration of responses observed with ALK inhibitors in patients with ALK-positive metastatic non-small cell lung cancer (mNSCLC) (0:00) Current role of other systemic therapy options for the treatment of ALK-positive mNSCLC; management of oligometastatic disease (8:38) Local therapy approaches for treating CNS disease in ALK-positive mNSCLC (18:32) Tolerability profile of lorlatinib (23:28) Review of clinical investigator survey results (37:08) Novel ALK inhibitors under clinical development (53:22) CME information and select publications

Featuring a slide presentation and related discussion from Dr Justin F Gainor, including the following topics: Duration of responses observed with ALK inhibitors in patients with ALK-positive metastatic non-small cell lung cancer (mNSCLC) (0:00) Current role of other systemic therapy options for the treatment of ALK-positive mNSCLC; management of oligometastatic disease (8:38) Local therapy approaches for treating CNS disease in ALK-positive mNSCLC (18:32) Tolerability profile of lorlatinib (23:28) Review of clinical investigator survey results (37:08) Novel ALK inhibitors under clinical development (53:31) CME information and select publications

Welcome back to the pod! This week, we're diving deep into the science and strategy behind ultra recovery, speed training myths, and (yes) mid-run bananas.

⭐️ Want support with real-world strategies that actually work on your campus? We're doing that every day in the School for School Counselors Mastermind. Come join us! ⭐️**********************************We've got to stop calling it "defiance" when it's actually dysregulation.In this episode, we're pulling back the curtain on what ADHD really is- and why the strategies we often use in schools aren't cutting it. You'll learn:Why ADHD isn't a behavior problem (and what it actually is)The critical difference between knowing and doingWhy worksheets, clip charts, and “just try harder” don't workWhat school counselors can do instead to actually helpIf you've ever had a student who “knows the rules” but can't seem to follow them, this one's for you.And if you're tired of seeing kids punished for things they haven't learned how to manage yet?You're in the right place... Let's go!Resources:American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.Barkley, R. A. (1997). ADHD and the nature of self-control. New York, NY: Guilford Press.Barkley, R. A. (2011). Executive functions: What they are, how they work, and why they evolved. New York, NY: Guilford Press.Brown, T. E. (2013). A new understanding of ADHD in children and adults: Executive function impairments. Routledge.Centers for Disease Control and Prevention. (2022). Data and statistics about ADHD. https://www.cdc.gov/ncbddd/adhd/data.htmlQuinn, P. O., & Madhoo, M. (2014). A review of attention-deficit/hyperactivity disorder in women and girls: uncovering this hidden diagnosis. The primary care companion for CNS disorders, 16(3), 27250.Shaw, P., Eckstrand, K., Sharp, W., Blumenthal, J., Lerch, J. P., Greenstein, D. E. E. A., ... & Rapoport, J. L. (2007). Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. Proceedings of the national academy of sciences, 104(49), 19649-19654.**********************************Our goal at School for School Counselors is to help school counselors stay on fire, make huge impacts for students, and catalyze change for our roles through grassroots advocacy and collaboration. Listen to get to know more about us and our mission, feel empowered and inspired, and set yourself up for success in the wonderful world of school counseling.Hang out in our Facebook groupJump in, ask questions, share your ideas and become a part of the most empowering school counseling group on the planet! (Join us to see if we're right.)Join the School for School Counselors MastermindThe Mastermind is packed with all the things your grad program never taught you IN ADDITION TO unparalleled support and consultation. No more feeling alone, invisible, unappreciated, or like you just don't know what to do next. We've got you!Did someone share this podcast with you? Be sure to subscribe for all the new episodes!!

Featuring a slide presentation and related discussion from Dr Adrienne G Waks, including the following topics: Updated analyses from key studies of the 21-gene Recurrence Score® for localized ER-positive breast cancer (29:30) Four-year landmark analysis of the NATALEE trial of adjuvant ribociclib with nonsteroidal aromatase inhibitor for localized breast cancer (9:49) The PADMA trial of palbociclib with endocrine therapy compared to chemotherapy induction followed by endocrine therapy maintenance for hormone receptor (HR)-positive, HER2-negative metastatic breast cancer (mBC) (11:25) Imlunestrant with or without abemaciclib for metastatic ER-positive mBC (13:18) TROP2-directed antibody-drug conjugates (ADCs) datopotamab deruxtecan and sacituzumab tirumotecan for HR-positive/HER2-negative mBC (17:50) Recent analyses from the DESTINY-Breast06 trial of trastuzumab deruxtecan (T-DXd) after endocrine therapy for HR-positive, HER2-low or HER2-ultralow mBC (21:09) The ICARUS-BREAST01 Phase II trial of the HER3-targeted ADC patritumab deruxtecan for HR-positive/HER2-negative mBC (26:02) Updates from neoadjuvant/adjuvant trials of pembrolizumab (KEYNOTE-522) and atezolizumab (NSABP B-59/GBG 96-GeparDouze) for localized triple-negative breast cancer (TNBC) (27:36) Ten-year update of the OlympiA trial of adjuvant olaparib for patients with germline BRCA1/2-mutated HER2-negative localized breast cancer (31:23) Exploratory analysis of patients who did or did not receive prior PD-1/PD-L1 inhibition in the Phase III OptiTROP-Breast01 study of sacituzumab tirumotecan versus chemotherapy for previously treated advanced TNBC (32:56) CNS efficacy of T-DXd (DESTINY-Breast12 trial) and outcomes with palbociclib combined with anti-HER2 therapy (AFT-38 PATINA trial) for HER2-positive mBC (34:04) CME information and select publications

Step into the gym with brothers Derek and Jacob Wellock as they reignite their podcast journey with raw honesty and hard-earned wisdom. This conversation peels back the curtain on what really drives sustainable fitness results—finding that sweet spot between showing up consistently and pushing your limits with proper intensity.The brothers tackle fitness myths head-on, particularly the misunderstood concept of CNS fatigue that many use as a convenient excuse to skip workouts. Through personal examples and years of coaching experience, they explain why most gym-goers will never truly experience this phenomenon and how to recognize when you're genuinely pushing too hard versus not hard enough.What truly sets this discussion apart is their exploration of finding your "why" in fitness. Jacob shares his ambitious "1800-pound challenge" (a 600-pound deadlift, 500-pound squat, 400-pound clean, and 300-pound snatch), while Derek reflects on how his daughter's health crisis reshaped his approach to fitness as a gift we shouldn't take for granted. This powerful contrast shows how different motivations can fuel equally meaningful fitness journeys.Between amusing anecdotes about brotherly wrestling matches and thoughtful reflections on their decade-plus building Double Edge Fitness, the Wellocks deliver a masterclass in balancing work and recovery. Their faith-driven approach reminds us that fitness isn't just about looking better—it's about becoming our best selves for those who depend on us. Whether you're just starting your fitness journey or looking to break through plateaus, their practical wisdom will help you train smarter, not just harder.Follow us on Instagram here! https://www.instagram.com/doubleedgefitness/

Fibromyalgia is more than just chronic pain—it's a complex condition that can leave sufferers feeling trapped in a cycle of exhaustion, brain fog, and sleepless nights. In this enlightening episode, The First Lady of Nutrition sits down with Dr. Michael Lenz, an integrative medical doctor specializing in fibromyalgia, to break down the science behind this often-misunderstood condition. Dr. Lenz explains why fibromyalgia is different in how the brain processes pain, often leading to hypersensitivity and "plastic pain." He dives into how fibro is diagnosed, including the Widespread Pain Index and Symptom Severity Score, and reveals the lifestyle and dietary protocols that can help manage symptoms. Ann Louise and Dr. Lenz also talk about the fascinating connections between fibromyalgia, colic, restless leg syndrome, ADHD, and more. If you or a loved one struggle with fibromyalgia, this episode is a must-listen—offering real solutions and a deeper understanding of what's really going on in the body. Learn more about Dr. Lenz at https://www.conqueringyourfibromyalgia.com/. The post Unraveling Fibromyalgia: Diagnosing and Treating Chronic Pain – Episode 191: Dr. Michael Lenz first appeared on Ann Louise Gittleman, PhD, CNS.

This podcast episode explores leadership principles through the lens of inversion—focusing on what not to do to become a better leader. Bradley Hartmann shares insights from CNS 5632:Leadership Principles in Construction within the University of Oklahoma's MBA program for construction professionals, which was heavily influenced by Charlie Munger's mental models. The episode provides a comprehensive list of leadership "don'ts" developed collaboratively with students, covering critical areas like emotional control, communication, delegation, and team management. Listeners will gain practical, actionable advice on avoiding common leadership pitfalls, such as micromanaging, stealing credit, ignoring team suggestions, and trying to be the smartest person in the room. This episode offers a refreshing, pragmatic approach to leadership development that goes beyond traditional motivational advice, as you'll receive a tangible framework for leadership improvement that emphasizes simplicity, self-awareness, and continuous learning. By understanding what to avoid, leaders can more effectively guide their teams, build trust, and create a positive organizational culture.    This episode is brought to you by The Simple Sales Pipeline® —the most efficient way to organize and value any construction sales rep's roster of customers and prospects in under 30 minutes once every 30 days. *** If you enjoyed this podcast, please leave a review on Apple Podcasts. Your feedback will help us on our mission to bring the construction community closer together. If you have suggestions for improvements, topics you'd like the show to explore, or have recommendations for future guests, do not hesitate to contact us directly at info@bradleyhartmannandco.com.  

Modafinil (Provigil) is a CNS stimulant medication. I cover modafinil pharmacology, adverse effects, drug interactions, and much more on this podcast episode. You should be aware that modafinil is a Schedule 4 controlled substance so it does carry a risk of dependence and addiction. Modafinil can cause CYP3A4 induction and lead to lowering the concentrations of many medications. This includes antiepileptic agents and oral contraceptives. The most common adverse effects of modafinil include ramping up the body and causing symptoms such as anxiety and insomnia. Cardiovascular changes are a risk with modafinil as this medication can contribute to hypertension and tachycardia.