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Những tuyến cao tốc được đầu tư để rút ngắn thời gian di chuyển, nâng cao năng lực kết nối và giảm áp lực cho mạng lưới giao thông. Thế nhưng, khi lưu lượng phương tiện ngày càng tăng, không ít điểm trên cao tốc vẫn xuất hiện ùn ứ, thậm chí kéo dài.Đáng chú ý, điểm nghẽn không phải lúc nào cũng nằm ở tuyến chính hay bắt nguồn từ thiếu làn đường. Dưới góc nhìn của VOV Giao thông Quốc gia, câu chuyện này cần được nhìn rộng hơn bởi "Cao tốc ùn tắc: Không chỉ là chuyện thiếu làn"
Tin tức tối 27-9: Bộ GD-ĐT sửa đổi 4 môn trong chương trình giáo dục thường xuyên cấp THCS, THPT; Cao tốc Bến Lức - Long Thành sắp hoàn thiện sau 12 năm thi công; Quốc lộ 1 qua Lâm Đồng chi chít ổ gà; Giả danh cảnh sát cơ động, chặn người đi đường gây chết người...
Read more from VPM News: Nearly 235K Virginians should never have been disenfranchised, state says 2nd District Q&A: Matt Baker, Jen Kiggans, Elaine Luria, Geral “Bishop” Staten Chesterfield food bank expands pantry network to 26 county schools Other links: Richmond schools have ‘zero' preventive maintenance, audit says amid mold issues (WRIC) As Council vets major solar deal, CAO says he's ‘extremely comfortable' with it (The Richmonder) UPDATED: Former Shoosmith Landfill owners indicted on felony charges (Richmond Times-Dispatch)* Dinwiddie families fear data center near their homes will upend wildlife, water and way of life (WTVR) *This outlet uses a paywall. Our award-winning work is made possible with your donations. Visit vpm.org/donate to support local journalism.
Christian organizations urging President Trump to raise with President Xi the case of an ailing pastor barred from leaving China...new survey shows religious affiliation growing among Gen Z...and pushback in public schools over Ten Commandment Laws.
VOV1 - Sau gần một thập kỷ triển khai, Chương trình “Mỗi xã một sản phẩm” (OCOP), tỉnh Lào Cai đã ghi dấu bằng những con số ấn tượng. Hàng trăm sản phẩm đặc trưng của địa phương được chuẩn hóa, xây dựng thương hiệu và từng bước tiếp cận thị trường. Tuy nhiên, đằng sau sự gia tăng mạnh mẽ về số lượng là một bài toán lớn đang được đặt ra: làm thế nào để sản phẩm OCOP không chỉ dừng lại ở một danh hiệu, mà thực sự tạo ra giá trị gia tăng, nâng cao thu nhập cho người dân và trở thành động lực phát triển kinh tế nông thôn bền vững.Theo Sở Công thương Lào Cai, đến nay, Chương trình "Mỗi xã một sản phẩm" (OCOP) tại địa bàn tỉnh đã chuẩn hóa gần 600 sản phẩm đặc sắc, góp phần khẳng định vị thế nông sản bản địa như Tương ớt Mường Khương, Cao mềm Actiso Sa Pa hay Trà Bát tiên Mường Hum. Tuy nhiên, để những "sản vật vùng cao" này thực sự lan tỏa giá trị, bài toán đặt ra hiện nay là chuyển tư duy từ "chạy theo danh hiệu" sang "phát triển kinh tế bền vững". Hà Nội: Tạm giữ hơn 93.000 sản phẩm thương hiệu Make Sense không có hóa đơn, chứng từ
AI is everywhere right now, but the most useful question isn't “what can it do?” It's “who does it work for?” We sit down with Neil Barnett, Microsoft's new Chief Accessibility Officer, to talk about what it takes to make technology work for everyone, especially people with disabilities, and why accessibility has to be treated as a core business priority rather than a bolt-on.We get into Microsoft's long accessibility history and the unglamorous work that actually creates progress: skilling, required accessibility training, and a culture where feedback is treated as a gift. Neil explains how he thinks about the CAO role as translating lived experience into better products and services, and we unpack what it looks like to keep accessibility consistent across a global organization through champions, frameworks, and shared accountability.Then we go deep on disability inclusion and the talent side of accessibility. Neil shares lessons from building inclusive hiring systems, including neurodiversity hiring, and why retention depends on processes like onboarding, manager capability, recruiter readiness, and accommodations. On AI, we move past the buzzword to real outcomes: captions, image descriptions, meeting recaps, and executive function support that many neurodivergent people now rely on, alongside the very real risk of overreliance and lost ideation.We also spotlight a practical resource more people should know about: Microsoft's Disability Answer Desk, which provides free support and creates a direct feedback loop into engineering. To wrap, we connect a classic accessibility habit to better AI results: accessible, well-structured documents help AI be more accurate because it needs clean, readable structure much like a screen reader does. Subscribe, share this with a colleague, and leave a review with your biggest takeaway.Send us Fan MailSupport the showFollow axschat on social media.Bluesky:Antonio https://bsky.app/profile/akwyz.comDebra https://bsky.app/profile/debraruh.bsky.socialNeil https://bsky.app/profile/neilmilliken.bsky.socialaxschat https://bsky.app/profile/axschat.bsky.socialLinkedInhttps://www.linkedin.com/in/antoniovieirasantos/ https://www.linkedin.com/company/axschat/https://www.linkedin.com/in/neilmilliken/Vimeohttps://vimeo.com/akwyzhttps://twitter.com/axschathttps://twitter.com/AkwyZhttps://twitter.com/neilmillikenhttps://twitter.com/debraruh
Christy Lake, Chief Administrative Officer at Twilio, joined us on The Modern People Leader. We talked about how AI is changing work, why skills, governance, and human judgment matter more than ever, and how Twilio is thinking about remote-first work, employee experience, and curiosity in the AI era.---- Sponsor Links:
Hay pacientes con daño cerebral que tienen fuerza, movilidad o equilibrio suficientes para hacer mucho más de lo que finalmente consiguen en su vida diaria. Y otros, aparentemente más afectados, terminan siendo mucho más independientes. ¿Qué explica esa discrepancia? En este episodio utilizamos el concepto pedagógico de "fenotipo premotor" para explorar todo lo que ocurre entre disponer de movimiento y conseguir convertirlo en una acción: selección, preparación, secuenciación, predicción, aprendizaje, automatización y transferencia. Hablamos de corteza premotora, complejo motor suplementario, sinergias, aprendizaje explícito e implícito, retención, generalización y de por qué a veces "da un paso largo” funciona mejor que “extiende la rodilla”. También revisamos estrategias clínicas y tecnologías que podrían ayudarnos cuando el verdadero problema no está simplemente en la fuerza o el tono. Porque en neurorrehabilitación no basta con conseguir más movimiento: necesitamos conseguir que ese movimiento se convierta en una acción útil, estable, transferible y autónoma. Referencias del episodio: 1. Antenucci, P., Moura, J., Bhatia, K. P., Rocchi, L., & Latorre, A. (2026). The Bereitschaftspotential in Voluntary Movement and Movement Disorders: Potential, Limitations and New Perspectives. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 187, 2111895. https://doi.org/10.1016/j.clinph.2026.2111895 (https://pubmed.ncbi.nlm.nih.gov/42013765/). 2. Ariani, G., Shahbazi, M., & Diedrichsen, J. (2025). Cortical Areas for Planning Sequences before and during Movement. The Journal of neuroscience : the official journal of the Society for Neuroscience, 45(3), e1300242024. https://doi.org/10.1523/JNEUROSCI.1300-24.2024 (https://pmc.ncbi.nlm.nih.gov/articles/PMC11735648/). 3. Boyd, L., & Winstein, C. (2006). Explicit information interferes with implicit motor learning of both continuous and discrete movement tasks after stroke. Journal of neurologic physical therapy : JNPT, 30(2), 46–59. https://doi.org/10.1097/01.npt.0000282566.48050.9b (https://pubmed.ncbi.nlm.nih.gov/16796767/). 4. Branscheidt, M., Hadjiosif, A. M., Anaya, M. A., Keller, J., Widmer, M., Runnalls, K. D., Luft, A. R., Bastian, A. J., Krakauer, J. W., & Celnik, P. A. (2025). Reinforcement Learning is Impaired in the Sub-acute Post-stroke Period. Neurorehabilitation and neural repair, 39(4), 297–311. https://doi.org/10.1177/15459683241304352 (https://pubmed.ncbi.nlm.nih.gov/39849897/). 5. Cattaneo, L., Nunes, S., Giampiccolo, D., Caro, V. D., Basaldella, F., Badari, A., Tagliaferri, M., Squintani, G., & Sala, F. (2025). Anatomical characterization of premotor-motor connectivity in humans by paired intraoperative direct cortical stimulation. NeuroImage, 324, 121621. https://doi.org/10.1016/j.neuroimage.2025.121621 (https://pubmed.ncbi.nlm.nih.gov/41314273/). 6. Demeco, A., Marotta, N., Lentini, M. P., Fratto, C., Loiarro, G., Frizziero, A., Salerno, A., Cerasa, A., de Sire, A., & Ammendolia, A. (2026). Mental simulation practices in stroke rehabilitation reorganize brain connectivity: a systematic review. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 35(9), 108719. https://doi.org/10.1016/j.jstrokecerebrovasdis.2026.108719 (https://pubmed.ncbi.nlm.nih.gov/42537726/). 7. Denyer, R., Greenhouse, I., & Boyd, L. A. (2023). PMd and action preparation: bridging insights between TMS and single neuron research. Trends in cognitive sciences, 27(8), 759–772. https://doi.org/10.1016/j.tics.2023.05.001 (https://pubmed.ncbi.nlm.nih.gov/37244800/). 8. Fridman, E. A., Hanakawa, T., Chung, M., Hummel, F., Leiguarda, R. C., & Cohen, L. G. (2004). Reorganization of the human ipsilesional premotor cortex after stroke. Brain : a journal of neurology, 127(Pt 4), 747–758. https://doi.org/10.1093/brain/awh082 (https://pubmed.ncbi.nlm.nih.gov/14749291/). 9. Fried, I., Katz, A., McCarthy, G., Sass, K. J., Williamson, P., Spencer, S. S., & Spencer, D. D. (1991). Functional organization of human supplementary motor cortex studied by electrical stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 11(11), 3656–3666. https://doi.org/10.1523/JNEUROSCI.11-11-03656.1991 (https://pubmed.ncbi.nlm.nih.gov/1941101/). 10. Fu, Y., Wang, W., Yan, Q., Song, J., Li, Y., Zhu, C., Chai, S. C., Subramaniam, P., Yao, L., & Singh, D. K. A. (2026). Comparative effects of transcranial direct and alternating current stimulation combined with cognitive-motor dual-task training on functional and cognitive recovery in stroke survivors. Frontiers in neurology, 17, 1720429. https://doi.org/10.3389/fneur.2026.1720429 (https://pubmed.ncbi.nlm.nih.gov/41725712/). 11. Garcea, F. E., & Buxbaum, L. J. (2023). Mechanisms and neuroanatomy of response selection in tool and non-tool action tasks: Evidence from left-hemisphere stroke. Cortex; a journal devoted to the study of the nervous system and behavior, 167, 335–350. https://doi.org/10.1016/j.cortex.2023.06.012 (https://pmc.ncbi.nlm.nih.gov/articles/PMC10543550/). 12. Genkin, M., Shenoy, K. V., Chandrasekaran, C., & Engel, T. A. (2025). The dynamics and geometry of choice in the premotor cortex. Nature, 645(8079), 168–176. https://doi.org/10.1038/s41586-025-09199-1 (https://pubmed.ncbi.nlm.nih.gov/40562938/). 13. Jahfari, S., Waldorp, L., van den Wildenberg, W. P., Scholte, H. S., Ridderinkhof, K. R., & Forstmann, B. U. (2011). Effective connectivity reveals important roles for both the hyperdirect (fronto-subthalamic) and the indirect (fronto-striatal-pallidal) fronto-basal ganglia pathways during response inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(18), 6891–6899. https://doi.org/10.1523/JNEUROSCI.5253-10.2011 (https://pubmed.ncbi.nlm.nih.gov/21543619/). 14. Kim, M. S., Park, H., Kwon, I., An, K. O., Kim, H., Park, G., Hyung, W., Im, C. H., & Shin, J. H. (2025). Efficacy of brain-computer interface training with motor imagery-contingent feedback in improving upper limb function and neuroplasticity among persons with chronic stroke: a double-blinded, parallel-group, randomized controlled trial. Journal of neuroengineering and rehabilitation, 22(1), 1. https://doi.org/10.1186/s12984-024-01535-2 (https://pubmed.ncbi.nlm.nih.gov/39757218/). 15. Koyama, T., & Domen, K. (2017). Diffusion Tensor Fractional Anisotropy in the Superior Longitudinal Fasciculus Correlates with Functional Independence Measure Cognition Scores in Patients with Cerebral Infarction. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 26(8), 1704–1711. https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.03.034 (https://pubmed.ncbi.nlm.nih.gov/28478977/). 16. Liepmann, H. (1900). Das Krankheitsbild der Apraxie (Motorische asymbolie): Auf Grund eines Falles von einseitiger Apraxie. Monatschrift für Psychiatrie und Neurologie, 8, 15-44 (https://www.mpi.nl/publications/item2354912/das-krankheitsbild-der-apraxie-motorische-asymbolie-auf-grund-eines-falles). 17. Meehan, S. K., Randhawa, B., Wessel, B., & Boyd, L. A. (2011). Implicit sequence-specific motor learning after subcortical stroke is associated with increased prefrontal brain activations: an fMRI study. Human brain mapping, 32(2), 290–303. https://doi.org/10.1002/hbm.21019 (https://pubmed.ncbi.nlm.nih.gov/20725908/). 18. Mihara, M., Hattori, N., Hatakenaka, M., Yagura, H., Kawano, T., Hino, T., & Miyai, I. (2013). Near-infrared spectroscopy-mediated neurofeedback enhances efficacy of motor imagery-based training in poststroke victims: a pilot study. Stroke, 44(4), 1091–1098. https://doi.org/10.1161/STROKEAHA.111.674507 (https://pubmed.ncbi.nlm.nih.gov/23404723/). 19. Mihara, M., Fujimoto, H., Hattori, N., Otomune, H., Kajiyama, Y., Konaka, K., Watanabe, Y., Hiramatsu, Y., Sunada, Y., Miyai, I., & Mochizuki, H. (2021). Effect of Neurofeedback Facilitation on Poststroke Gait and Balance Recovery: A Randomized Controlled Trial. Neurology, 96(21), e2587–e2598. https://doi.org/10.1212/WNL.0000000000011989 (https://pubmed.ncbi.nlm.nih.gov/33879597/). 20. Nachev, P., Kennard, C., & Husain, M. (2008). Functional role of the supplementary and pre-supplementary motor areas. Nature reviews. Neuroscience, 9(11), 856–869. https://doi.org/10.1038/nrn2478 (https://pubmed.ncbi.nlm.nih.gov/18843271/). 21. Park, S. H., Yan, S., Dee, W., Reed, R., Roth, E. J., Rymer, W. Z., & Wu, M. (2022). Repeated adaptation and de-adaptation to the pelvis resistance force facilitate retention of motor learning in stroke survivors. Journal of neurophysiology, 127(6), 1642–1654. https://doi.org/10.1152/jn.00046.2022 (https://pubmed.ncbi.nlm.nih.gov/35583975/). 22. Paul, T., Cieslak, M., Hensel, L., Wiemer, V. M., Tscherpel, C., Grefkes, C., Grafton, S. T., Fink, G. R., & Volz, L. J. (2024). Corticospinal premotor fibers facilitate complex motor control after stroke. Annals of clinical and translational neurology, 11(9), 2439–2449. https://doi.org/10.1002/acn3.52159 (https://pubmed.ncbi.nlm.nih.gov/39073030/). 23. Potgieser, A. R., de Jong, B. M., Wagemakers, M., Hoving, E. W., & Groen, R. J. (2014). Insights from the supplementary motor area syndrome in balancing movement initiation and inhibition. Frontiers in human neuroscience, 8, 960. https://doi.org/10.3389/fnhum.2014.00960 (https://pmc.ncbi.nlm.nih.gov/articles/PMC4246659/). 24. Zhang, Y., Zhang, Y., Zheng, B., Chen, S., Yu, H., Dai, L., Zhang, W., Huang, H., Su, X., Cao, M., & Chen, J. (2025). The effects of combining anodal transcranial direct current stimulation with robot-assisted gait training on lower limb motor function and the motor cortex regulation of stroke patients. Journal of neuroengineering and rehabilitation, 22(1), 230. https://doi.org/10.1186/s12984-025-01731-8 (https://pubmed.ncbi.nlm.nih.gov/41163056/). 25. Zhang, Y. S., Li, Y. D., Ou, C. X., Bi, Z. T., Xiao, J. H., Zhang, J. M., Wei, J. X., Xu, J. W., & Huang, L. (2026). Comparative efficacy and mechanistic insights of non-invasive neuromodulation and motor rehabilitation on functional reorganization of the supplementary motor area in subacute stroke: a narrative review. Frontiers in physiology, 17, 1744260. https://doi.org/10.3389/fphys.2026.1744260 (https://pubmed.ncbi.nlm.nih.gov/42005313/). 26. Zhou, Y., Li, X., Huang, W., Xie, H., Zheng, Y., Su, L., Xiang, H., Zhou, H., Jiang, W., & Dou, Z. (2026). Predicting activities of daily living at discharge in stroke patients using rehabilitation robot training-induced functional connectivity. Topics in stroke rehabilitation, 33(6), 618–629. https://doi.org/10.1080/10749357.2026.2612712 (https://pubmed.ncbi.nlm.nih.gov/41496182/).
Ngày 1-9 theo giờ địa phương, Tổng thống Mỹ Donald Trump đề cử Quyền Bộ trưởng Hải quân Hùng Cao làm Bộ trưởng Hải quân chính thức và hối thúc Thượng viện nhanh chóng phê chuẩn.
Beidh scoláirí na hArdteistiméireachta ag fáil a dtairiscintí CAO maidin amárach.See omnystudio.com/listener for privacy information.
On the Young Stock Podcast this week, Sarah McIntosh and Daire Cregg discuss CAO points, going to college and offer advice to students navigating their next steps. They are joined by this week's guest, Leo Walsh who is preparing to compete in the two-furrow (two-fur) novice class at this year's National Ploughing Championships in Screggan, Co Offaly on 15-17 September.Leo discusses how he deals with the pressures of competing, where his ploughing knowledge came from and the final preparations that are currently underway.As well as the Ploughing, Leo is getting ready to start college this September. Hosted on Acast. See acast.com/privacy for more information.
On Tuesday's Morning Focus, Alan Morrissey was joined by John Burns, Chair of the board at Rice College and Educational Consultant. This week, John shared practical advice on the CAO process and the important decisions students face when considering further education. The discussion also looks at the annual challenges of returning to school, focusing on the do's and don'ts for students as they begin a new academic year. Image (c) Clare FM
With the first round of CAO offers now out, college has become less of a far away possibility to now a reality. One thing that will be an issue for many is how they will pay for everything, from fees to accommodation. So, how do you get the money together?Newstalk's Dylan Hand has been putting together the ultimate college survival guide, and joins Ciara to discuss!
VOV1 - Để đảm bảo công tác cung cấp điện phục vụ nhân dân và các sự kiện quan trọng trong dịp Lễ Quốc khánh năm nay, Tổng công ty Điện lực TP.HCM (EVNHCMC) đã chỉ đạo các đơn vị thành viên không thực hiện các thao tác trên lưới, làm mất điện khách hàng.Theo đó, EVNHCMC đã quán triệt đến từng cán bộ công nhân viên tầm quan trọng của việc đảm bảo điện đối với sự kiện chính trị trọng đại này. EVNHCMC yêu cầu các đơn vị tuyệt đối không chủ quan, không để xảy ra sai sót trong quá trình triển khai thực hiện đảm bảo cung cấp điện.Các Công ty Điện lực khu vực và Công ty Lưới điện Cao thế tăng cường kiểm tra, phát hiện và xử lý kịp thời các khiếm khuyết của thiết bị nguồn, lưới điện. Hành lang các tuyến dây cần được phát quang để đảm bảo an toàn lưới điện, đồng thời đẩy mạnh công tác tuyên truyền, nâng cao nhận thức người dân về hành lang an toàn lưới điện và ổn định cho ngày nghỉ lễ. Lập phương án đảm bảo cung cấp điện trong thời gian nghỉ lễ Quốc khánh và tổ chức diễn tập tại địa điểm tổ chức lễ mít tinh, diễu hành sự kiện, lễ hội trên địa bàn quản lý.Các Công ty Điện lực chủ động, phối hợp với chính quyền địa phương tăng cường các biện pháp bảo vệ an ninh đối với các công trình điện; rà soát, xây dựng và triển khai các phương án bảo vệ an ninh, an toàn, phòng chống cháy nổ cho các công trình điện và tuyên truyền ngăn ngừa các trường hợp vi phạm hành lang tuyến dây. Các đơn vị này phải thực hiện đảm bảo cung cấp điện an toàn và ổn định điện cho các khu vực diễn ra các sự kiện.Trung tâm Điều độ hệ thống điện ngoài việc thực hiện các chức năng chuyên môn, phải phối hợp chặt chẽ với Công ty Lưới điện Cao thế và các Công ty Điện lực để đảm bảo cấp điện ưu tiên cho các sự kiện. Trong khi đó, các công ty trực thuộc EVNHCMC tổ chức bố trí lực lượng trực vận hành và tăng cường nhân sự trực tại các trạm trọng điểm (nếu cần thiết); chuẩn bị sẵn sàng lực lượng, vật tư, phương tiện, thiết bị để xử lý kịp thời các tình huống sự cố phát sinh trong suốt thời gian diễn ra sự kiện. PV/VOV TPHCMNhân viên điện lực rà soát, sửa chữa các tuyến dây
CAO offers and the end of a sunny summer can make us all ponder our career choices. If you are doing a job you really don't like, and you need to make a dramatic change, where do you start? And does your age preclude you from making that career leap?Joining Tom Dunne to discuss is Peter Cosgrove, Managing Director at Careers Portal.
Lillian Griffin, Admissions Officer MTU, talks course selection, CAO offer/acceptance and starting college with PJ Hosted on Acast. See acast.com/privacy for more information.
The first round of CAO offers for 2026 will be released this afternoon at 2pm, marking another important milestone for Leaving Cert students across the country. But for those who don't get the offer they were hoping for, there are still a number of options available, including further CAO rounds and Available Places. Mary Tyrell from Careerfocus in Ennis joined Alan Morrissey to talk through what students need to know and what their next steps should be. Photo (c) YinYang from Getty Images Signature via Canva
Today, CAO applicants across the country will receive their offers for third-level education. With us to give advice on how to prepare, and what to do once you get your offer was Gemma Lawlor, Guidance Counsellor at Tyndall College Carlow.
The first CAO offers have been released today for those who have completed their Leaving Cert hoping to get their top choices.Minister for Education James Lawless joins Shane to discuss the results…
CAO offers are out today, which officially ushers in the new academic year.However, while new or returning students should be excited, many are stressed as they struggle to secure accommodation…Listeners join guest host Clare McKenna to share their experiences.
Louth GAA Captain Sam Mulroy speaks to Gerry on Lite Lunch about getting his dreams, without filling in a CAO form Hosted on Acast. See acast.com/privacy for more information.
CAO offers and the end of a sunny summer can make us all ponder our career choices. If you are doing a job you really don't like, and you need to make a dramatic change, where do you start? And does your age preclude you from making that career leap?Joining Tom Dunne to discuss is Peter Cosgrove, Managing Director at Careers Portal.
Today, CAO applicants across the country will receive their offers for third-level education. With us to give advice on how to prepare, and what to do once you get your offer was Gemma Lawlor, Guidance Counsellor at Tyndall College Carlow.
On today's show, GAA Louth captain Sam Mulroy spoke of his education journey to a Masters - and it didn't contain a CAO form, there's a new artist in Navan, parenting on the first day at school and so much more! Hosted on Acast. See acast.com/privacy for more information.
New survey shows parents are ringing creches from the maternity ward in the hopes of securing a space, faulty goods, pricing and contract performance among the issues consumers turned to the CCPC about in the first half of this year, plans for an arts venue in West Cork get the green light from Cork County Council and Show Counsellor Joe Heffernan shares advice for those waiting on CAO offers Hosted on Acast. See acast.com/privacy for more information.
Yesterday, thousands of Leaving Cert students received their results around the country. Though a few would have been over the moon, many will have been disappointed and worried about what their results will mean for their chances in next week's CAO round one offers. Joining Bobby to reflect on results day and look towards next week's offers is Guidance counsellor and Education Columnist, Brian Mooney.
On Friday, Acting Navy Secretary Hung Cao announced that the aircraft carrier USS Abraham Lincoln (CVN-72) is returning to the United States as part of a “planned rotation.” Cao's announcement follows weeks of reporting on strained conditions aboard the ship, including food and supply shortages, mental health struggles among sailors, and multiple sailors reportedly attempting to jump overboard. Aside from brief stops in Guam in December and Oman in July, the carrier has been operating for 271 days at sea without its crew taking a port call. The Japan-based USS George Washington (CVN-73) is set to relieve the Lincoln.Ad-free podcasts are here!Get 20% off your first year of ad-free episodes, exclusive interviews, and deep dives with Tangle's podcast membership!The real story of the Reflecting Pool.By now, you've almost certainly heard about the controversy over President Trump's renovations to the Reflecting Pool in Washington, D.C. But while most news reports have focused on alleged vandalism and administration infighting, questions remain about what, exactly, went wrong. In our latest video, Associate Producer Aidan Gorman reports from the National Mall. You can watch it here. You can read today's podcast here and today's “Have a nice day” story here.You can subscribe to Tangle by clicking here or drop something in our tip jar by clicking here. Take the survey: Are you concerned about U.S. military readiness? Let us know.Our Executive Editor and Founder is Isaac Saul. Our Executive Producer is Jon Lall.This podcast written by: Will Kaback and audio engineered and edited by Dewey Thomas. Music for the podcast was produced by Diet 75.Our newsletter is edited by Managing Editor Ari Weitzman, Senior Editor Will Kaback, Bailey Saul, Audrey Moorehead, and Carina Pacheco. Hosted on Acast. See acast.com/privacy for more information.
VOV1 - Sau khi hợp nhất, công tác đảm bảo TTATGT tại tỉnh Tuyên Quang bước sang một giai đoạn mới, địa bàn trải dài hơn, quản lý phức tạp hơn. Chính vì vậy, việc tuần tra, kiểm soát luôn được Phòng CSGT, Công an tỉnh Tuyên Quang bố trí lực lượng phù hợp theo thực tế từng địa bàn, khu vực. Hàng ngày, tại tỉnh Tuyên Quang nhiều đoàn du khách đi xe máy nối đuôi nhau trên các tuyến đường lên Cao nguyên đá Đồng Văn. Khách du lịch người nước ngoài đủ điều kiện lái xe có thể thuê xe máy tự lái, hoặc thuê xe ôm để thăm cảnh đẹp của cao nguyên đá. Cũng vì thế, từ nhiều năm qua làm xe ôm chở khách được nhiều người dân địa phương coi là một nghề “ hót” ở tỉnh Tuyên Quang.Chị Vừ Thị Páo, ở xã Thuận Hòa, tỉnh Tuyên Quang làm nghề xe ôm gần được 2 năm, thu nhập 1 tháng cũng được gần 10 triệu đồng, chia sẻ:(Cũng cần phải đi quen đường, đi theo nhóm thì cũng phải theo thẳng hàng thì dễ hơn. Phải đi chuẩn hàng lái xe không quá tốc độ 40-50km/h, đường đèo chỉ đi khoảng 25-30 km/h thôi).Anh Phàn Quốc Vài ở xã Thuận Hòa, tỉnh Tuyên Quang cũng làm nghề xe ôm chở khách du lịch cho biết.(Một ngày mình đi đến Đồng Văn ngủ lại, hôm sau về Du Già, hôm thứ 3 về Hà Giang. Hướng dẫn viên hướng dẫn mình đi đảm bảo cho khách và đảm bảo cho mình. Khách tự lái phải có bằng và phải tự đặt xe. Đi trên đường khách muốn lái không cho lái vì không an toàn).
Astronomy Daily · S05E163 · “The Long Way Home” · Monday 10 August 2026. Sources verified against primary / institutional outlets. Starship “lost at sea” (Flight 13) • Flight 13 launched 24 July 2026 from Starbase, South Texas; the upper stage (“Ship,” Ship 40, ~52 m) made the softest Starship water landing yet in the Indian Ocean off Western Australia — and, in a program first, survived intact and afloat. • SpaceX had not planned to recover it. Musk confirmed the salvage attempt on 28 July (“We're sending a ship out to recover Starship”); recovery ship Go Australis was joined by Norwegian tugs Normand Ranger and Skimmer Tide, with a tow line to the nose. • On 7 August, Musk said recovery is “not looking good right now” in rough seas — but the team had already obtained close-up photos of critical heat-shield and engine regions for future upgrades. A saltwater-soaked Ship was never going to be reflown. • Heat shield: on SpaceX's first quarterly earnings call (4 August) Musk said he'd “consider the heat-shield problem solved,” long the biggest hurdle to full reuse. • The flight also deployed 20 next-gen Starlink V3 satellites; the Super Heavy booster had engine trouble and was lost in the Gulf of Mexico. Stacked, Starship stands ~124 m. Flight 14 is targeted for late August — its first attempt at operational orbit with production Starlink. • Sources: SpaceX / @elonmusk on X (7 Aug); Space.com (Mike Wall, 7 Aug); CNN (3 Aug). Landspace Zhuque-3, second landing attempt • Landspace (private, Beijing, founded 2015) targets liftoff ~7:45 p.m. EDT Mon 10 Aug (23:45 UTC / ≈9:45 a.m. AEST Tue 11 Aug) from Jiuquan, aiming for a propulsive first-stage recovery on legs (Falcon 9-style), landing downrange in Gansu. • The methalox, stainless-steel Zhuque-3 (~66 m) is broadly a Falcon 9 rival. Its Dec 2025 maiden flight reached orbit but the first stage failed its landing burn and crashed. • Accuracy note: this is China's fourth orbital-class recovery attempt. A Long March 10B already landed via net-capture on 10 July (China became the 2nd nation to land an orbital booster) — so tonight would make Landspace the first Chinese company to attempt a propulsive/landing-legs recovery, not “China's first.” • Sources: Space.com (7 Aug); Yahoo/Space (7 Aug); launch trackers (NOTAM-based). Uranus's “breathing” bow shock • New multifluid-MHD modelling shows Uranus's bow shock expands and contracts over a single ~17-hour Uranian day — driven by the planet's own extreme rotation and tilted, offset magnetic field, not by changes in the solar wind. • The model is constrained by Voyager 2's 1986 flyby — still the only direct measurements ever taken inside the Uranian system (a nice callback to E159's Voyager 2 “Big Bang” lead). • Implications for future ice-giant missions and for the many ice-giant exoplanets now being found. Cao et al., AGU Advances; surfaced via an Eos research spotlight this week. (Framed as newly-spotlighted rather than newly-published.) • Sources: AGU Advances (Cao et al.); Eos research spotlight; phys.org (7 Aug). Total solar eclipse — 12 August 2026 • The only total solar eclipse of 2026. Unusual over-the-pole path: Arctic Siberia → eastern Greenland → western Iceland → northern Spain (clipping NE Portugal) → the Balearics at sunset. • Greatest eclipse ≈17:46 UTC; max totality 2 min 18 s just off Iceland's west coast, with the Sun only ~26° high. Iceland's first total eclipse since 1954 (Reykjavik's first in 593 years); Spain's first since 1905. • North America sees a partial across the northern tier (Alaska to North Carolina) and most of Canada — deepest in the far north, a shallow bite (
Ondanks dat biotechbedrijf Leyden Labs gestage vooruitgang boekt bij het ontwikkelen van zijn eerste antivirale neusspray, boekt het bedrijf nog altijd geen omzet. Toch blijken investeerders telkens weer bereid tientallen miljoenen in het Leidse bedrijf te stoppen. Koenraad Wiedhaup, medeoprichter en directeur van Leyden Labs is te gast in BNR Zakendoen. Macro met Mujagić Elke dag een intrigerende gedachtewisseling over de stand van de macro-economie. Op dinsdag en vrijdag gaat presentator Thomas van Zijl in gesprek met econoom Arnoud Boot, de rest van de week praat Van Zijl met econoom Edin Mujagić. Ook altijd terug te vinden als je een aflevering gemist hebt. Blik op de wereld Wat speelt zich vandaag af op het wereldtoneel? Het laatste nieuws uit bijvoorbeeld Oekraïne, het Midden-Oosten, de Verenigde Staten of Brussel hoor je iedere werkdag om 12.10 van onze vaste experts en eigen redacteuren en verslaggevers. Ook los te vinden als podcast. Economenpanel Klaas Knot is dé vervanger van Christine Lagarde wat de Nederlandse overheid betreft. En: de werkelijke loongroei is vaak hoger dan de CAO-loongroei, moeten we daardoor anders naar koopkrachtanalyses gaan kijken? Dat en meer bespreekt presentator Thomas van Zijl vanaf 11.00 in het economenpanel met: Jan-Paul van de Kerke, hoofd Nederland bij het economisch bureau van ABN Amro. en Roelof Salomons, Chief Investment Strategist bij BlackRock. Luister l Economenpanel Zakenlunch Elke dag, tijdens de lunch, geniet je mee van het laatste zakelijke nieuws, actuele informatie over de financiële markten en ander economische actualiteiten. Op een ontspannen manier word je als luisteraar bijgepraat over alles wat er speelt in de wereld van het bedrijfsleven en de beurs. En altijd terug te vinden als podcast, mocht je de lunch gemist hebben. Contact & Abonneren BNR Zakendoen zendt elke werkdag live uit van 11:00 tot 13:30 uur. Je kunt de redactie bereiken via e-mail. Abonneren op de podcast van BNR Zakendoen kan via bnr.nl/zakendoen, of via Apple Podcast en Spotify. See omnystudio.com/listener for privacy information.
VOV1 - Chuyển đổi số đang trở thành giải pháp quan trọng giúp nông nghiệp Hà Nội nâng cao giá trị sản phẩm, minh bạch nguồn gốc và đáp ứng yêu cầu ngày càng cao của thị trường trong nước cũng như xuất khẩu.Tại nhiều địa phương, công nghệ số đã được đưa vào sản xuất. Ở xã Bát Tràng, Hợp tác xã Văn Đức triển khai dán tem điện tử trên ứng dụng HaNoi Trace để truy xuất nguồn gốc sản phẩm cải ngọt. Hơn 200 héc-ta vùng chuyên canh tại đây đã áp dụng nhật ký điện tử và gắn biển nhận diện từng thửa ruộng. Trong khi đó, Hợp tác xã Đông Cao, xã Mê Linh, sử dụng phần mềm xacthucso.vn kết hợp mã QR để truy xuất nguồn gốc trên 547 héc-ta rau tập trung.Theo Sở Nông nghiệp và Môi trường Hà Nội, hệ thống truy xuất nguồn gốc check.hanoi.gov.vn đã cấp tài khoản cho hơn 3.300 cơ sở, quản lý dữ liệu trên 12.300 sản phẩm. Thành phố cũng đang kết nối dữ liệu với Bộ Nông nghiệp và Môi trường, ưu tiên các sản phẩm chủ lực như thịt lợn, thịt gà, rau và trà hoa vàng Sóc Sơn. Cùng với đó, hơn 26.800 hồ sơ tự công bố sản phẩm đã được công khai, tỷ lệ đạt yêu cầu của hệ thống kiểm tra kiến thức an toàn thực phẩm đạt trên 93,6%.Thời gian tới, Hà Nội tiếp tục đẩy mạnh tập huấn kỹ năng số cho nông dân, mở rộng các chuỗi liên kết an toàn, góp phần xây dựng nền nông nghiệp hiện đại, minh bạch và phát triển bền vững./.Hà Nội khuyến khích nông dân ứng dụng công nghệ số, truy xuất nguồn gốc và các tiêu chuẩn sản xuất an toàn nhằm nâng cao giá trị nông sản, đáp ứng yêu cầu của thị trường và bảo vệ sức khỏe người tiêu dùng
VOV1 - Những bức ảnh bị phai mờ sau hơn 50 năm nằm sâu trong lòng đất vừa được Đội K72 cẩn trọng thu thập tại xã Minh Đức, TP. Đồng Nai và nhờ các bạn trẻ phục dựng. Từ những di ảnh vừa được hồi sinh, một hành trình đong đầy hy vọng đang mở ra là tìm lại tên tuổi và đưa các anh trở về với gia đình.Những di vật biết nói dưới lòng đấtTrong đợt tìm kiếm, quy tập hài cốt liệt sĩ tại lô cao su 97, thuộc nông trường Cao su Bình Long, xã Minh Đức, TP. Đồng Nai (trước là huyện Hớn Quản, tỉnh Bình Phước), các cán bộ, chiến sĩ Đội K72 thuộc Bộ Chỉ huy Quân sự TP. Đồng Nai đã có những giây phút nghẹn ngào.Tại một hầm mộ quy tập được 4 hài cốt liệt sĩ, bên cạnh cây bút khắc dòng chữ “Tiến Quy”, lực lượng chức năng phát hiện một bức ảnh tập thể. Ở một hầm mộ khác có 3 hài cốt, trong chiếc ví đã sờn cũ của người nằm xuống cũng cất giữ một tấm di ảnh cá nhân.Nằm dưới lòng đất hơn nửa thế kỷ, các tài liệu, giấy tờ và ảnh chụp đều đã bị mục rã, phai mờ. Bằng tình cảm và sự tri ân sâu sắc, các cán bộ, chiến sĩ Đội K72 đã vô cùng tỉ mỉ, nâng niu từng mảnh di vật để tránh bị rách hỏng, đồng thời lập tức chụp lưu lại hình ảnh trước khi không khí làm hư hại thêm.Chia sẻ về khoảnh khắc đặc biệt này, Đại úy Nguyễn Vũ Huy, Phân đội trưởng Phân đội 2, Đội K72 nghẹn ngào: "Khi đào tìm mà phát hiện hài cốt và các di vật của các liệt sĩ, cán bộ, chiến sĩ chúng tôi bồi hồi, xúc động ở trong đó. Tự bảo nhau làm việc thực là tỉ mỉ, nhẹ nhàng, di vật và hài cốt đem về cho thân nhân liệt sĩ nhận dạng. Đối với những hình ảnh vừa rồi, tôi hi vọng là truyền thông rộng rãi để thân nhân kịp thời nắm bắt và nhận dạng được liệt sĩ của mình."Hồi sinh di ảnh, nối lại nhịp cầu ký ứcNgay sau khi tiếp cận và lưu giữ các hình ảnh, Đội K72 đã nhanh chóng phối hợp cùng các cộng tác viên, những bạn trẻ giàu tâm huyết để tiến hành phục dựng.Từ những tấm hình mờ nhòe của thời gian, qua công nghệ và sự trân trọng của thế hệ trẻ, hình ảnh các chiến sĩ năm xưa đã trở nên rõ nét.Tấm ảnh tập thể được tìm thấy dưới hầm mộ có 4 liệt sĩ
For most of the last century, gardeners were taught to cultivate their soil after every rain to conserve moisture, to think of plant roots as lone competitors, and to treat "plant communication" as science fiction. All of that was built on the best evidence available at the time, and all of it has been revised, in some cases more than once, as better tools let researchers see what earlier generations simply could not. In this episode, we walk through four real case studies of plant science changing its mind. Along the way, we talk about how the scientific method works, why one of my favorite phrases, "we don't know what we don't know," is not a discouraging idea but an exciting one, and what all of this means for the choices you make in your own garden each season, now and into the future. Let's dig in! References and Resources: Chalker-Scott, L., and C.H. Daniels. (2016). "Scientific Literacy for the Citizen Scientist." WSU Extension Manual EM100E. https://wpcdn.web.wsu.edu/extension/uploads/sites/30/2024/07/Scientific-Literacy-for-the-Citizen-Scientist.pdf Chalker-Scott, L. (2021, revised). "Dust Mulch Efficacy in Gardens and Landscapes." WSU Extension Fact Sheet FS167E. https://wpcdn.web.wsu.edu/wp-ecommerce/uploads/sites/2/product-3540-sku-FS167E.pdf Chalker-Scott, L. (2017). "A Gardener's Primer to Mycorrhizae: Understanding How They Work and Learning How to Protect Them." WSU Extension Fact Sheet FS269E. https://wpcdn.web.wsu.edu/wp-ecommerce/uploads/sites/2/product-3286-sku-FS269E.pdf Chalker-Scott, L. (2023). "Gardening with Companion Plants." WSU Extension Publication EM128E. https://pubs.extension.wsu.edu/product/gardening-with-companion-plants-home-garden-series/ Oklahoma State University Extension. "Mycorrhizal Fungi." Fact Sheet. https://extension.okstate.edu/fact-sheets/mycorrhizal-fungi Pacific Horticulture Society. "Mycorrhizal Fungi, Nature's Key to Plant Survival and Success." https://pacifichorticulture.org/articles/mycorrhizal-fungi-natures-key-to-plant-survival-and-success/ Cao, D., Chabikwa, T., Barbier, F., Dun, E.A., Fichtner, F., Dong, L., Kerr, S.C., & Beveridge, C.A. (2023). "Auxin-independent effects of apical dominance induce changes in phytohormones correlated with bud outgrowth." Plant Physiology, 192(2), 1420–1434. https://doi.org/10.1093/plphys/kiad034 Mason, M.G., Ross, J.J., Babst, B.A., Wienclaw, B.N., & Beveridge, C.A. (2014). "Sugar demand, not auxin, is the initial regulator of apical dominance." Proceedings of the National Academy of Sciences, 111(16), 6092–6097. https://www.pnas.org/doi/10.1073/pnas.1322045111 Barbier, F.F., Dun, E.A., & Beveridge, C.A. (2017). "A Growing Stem Inhibits Bud Outgrowth — The Overlooked Theory of Apical Dominance." Frontiers in Plant Science, 8:1874. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671643/ "Lessons from a century of apical dominance research." (2023). Journal of Experimental Botany. https://pmc.ncbi.nlm.nih.gov/articles/PMC10400159/ Simard, S.W., Perry, D.A., Jones, M.D., Myrold, D.D., Durall, D.M., & Molina, R. (1997). "Net transfer of carbon between ectomycorrhizal tree species in the field." Nature, 388, 579–582. https://www.nature.com/articles/41557 "Belowground carbon transfer across mycorrhizal networks among trees: Facts, not fantasy." (2023). Review discussing the scope and limits of current evidence for mycorrhizal carbon transfer. https://pmc.ncbi.nlm.nih.gov/articles/PMC10751480/ Baldwin, I.T., & Schultz, J.C. (1983). "Rapid Changes in Tree Leaf Chemistry Induced by Damage: Evidence for Communication Between Plants." Science, 221(4607), 277–279. https://www.science.org/doi/10.1126/science.221.4607.277 Heil, M. (2014). "Herbivore-induced plant volatiles: targets, perception and unanswered questions." New Phytologist, 204(2), 297–306. https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.12977 Just Grow Something: https://justgrowsomething.com Gardening Courses: https://justgrowsomething.com/courses Just Grow Something Merch and Downloads: https://justgrowsomething.com/shop Just Grow Something Gardening Friends Facebook Group: https://www.facebook.com/share/g/18YgHveF5P/ Check out how you can become a patron on Patreon: https://www.patreon.com/JustGrowSomething Feed my coffee habit: https://buymeacoffee.com/justgrowsomething Amazon storefront: https://www.amazon.com/shop/justgrowsomething Get 10% off and FREE shipping on my favorite raised planters at Planter Box Direct using code JUSTGROW10: https://planterboxdirect.com/?ref=593 Save on your Aquatru water system at Aquatru.com using code GROW. https://aquatru.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Laudetur Jesus Christus - Ngợi khen Chúa Giêsu KitôRadio Vatican hằng ngày của Vatican News Tiếng Việt.Nội dung chương trình hôm nay:0:00 Bản tin16:04 Sinh hoạt Giáo hội : Ngày Thế giới Ông bà và Người Cao tuổi 2026: Đan kết các thế hệ và Khám phá ơn gọi trong sự mong manh---Những hình ảnh này thuộc Bộ Truyền Thông của Toà Thánh. Mọi sử dụng những hình ảnh này của bên thứ ba đều bị cấm và dẫn đến việc đánh bản quyền, trừ khi được cho phép bằng giấy tờ của Bộ Truyền Thông. Copyright © Dicasterium pro Communicatione - Giữ mọi bản quyền.
James and Jimmy sit down with Tim Ozgener of Oz Family Cigars at The Drawing Room in Davenport, Iowa. The trio discuss Tim's creativity, his history in the cigar industry, and the impact his father had on him. From his days with CAO to coming back to the industry, Tim dives into what lessons he learned, what his father taught him, his family, and working with retailers.
A busy council agenda but not before they break early for the summer. Ken Sim flip flops on the park board once more while making vague threats against the province. Metro Vancouver’s CAO is out and Richmond’s speeds are slowing. Links Opposition cries foul as Vancouver council scrubs last meeting before summer break | CBC News Village plan? New tallest towers? Vancouver council faces summer sprint | CBC News Vancouver Villages Plan draws massive turnout at city hall as debate over housing densification continues Vancouver mayor says he won’t try to eliminate the park board if re-elected | CBC News Vancouver mayor threatens ‘unprecedented' action against the province, can't say why it is necessary Vancouver mayor's office inquired about public plaza: FOI reveals Metro Vancouver CAO Jerry Dobrovolny could be on his way out – BC | Globalnews.ca Speed limit reduced to 30 km/h on residential roads in Richmond 30 km/h speed limits coming to Richmond neighbourhood streets | CBC News Trans-Canada Air Lines Flight 3 – Wikipedia Photo credit: Tannoy at Wikipedia
In this episode we speak with Alon Goren from UC San Diego about his work at the intersection of genomic technology development and chromatin biology. We discuss how his lab studies how the epigenome is regulated, how disruption of that regulation contributes to disease, and how technology can be improved to make results more robust and reproducible. We talk about his early interest in biology, how that developed through medical research training, and how a molecular biology lab shaped the direction of his career. He explains how curiosity about how cells and organisms work led him toward genomics and chromatin research. We then discuss several methods from his career, including early direct sequencing approaches for small amounts of DNA and RNA, ChIP-based methods for chromatin regulators, and work on improving ChIP-seq workflows. He explains why antibody choice matters, why monoclonal antibodies can improve reproducibility, and how automation helped scale the process. We also cover his work on spike-in normalization, including the risks of using exogenous chromatin incorrectly and the need for better safeguards in genome-wide comparisons. He describes a newer approach that uses two spike-ins to provide multiple checks on normalization. Finally, we discuss his work on short tandem repeats, zebrafish heart regeneration, and SIRT6-related polymerase pausing, as well as a newer platform that converts molecular interactions into sequencing-readable barcodes. He closes by stressing the importance of validation, careful protocol design, and methods that can be used reliably by multiple people. References Ram, O., Goren, A., Amit, I., Shoresh, N., Yosef, N., Ernst, J., Kellis, M., Gymrek, M., Issner, R., Coyne, M., Durham, T., Zhang, X., Donaghey, J., Epstein, C. B., Regev, A., & Bernstein, B. E. (2011). Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells. Cell, 147(7), 1628–1639. https://doi.org/10.1016/j.cell.2011.09.057 Busby, M., Xue, C., Li, C., Farjoun, Y., Gienger, E., Yofe, I., Gladden, A., Epstein, C. B., Cornett, E. M., Rothbart, S. B., Nusbaum, C., & Goren, A. (2016). Systematic comparison of monoclonal versus polyclonal antibodies for mapping histone modifications by ChIP-seq. Epigenetics & chromatin, 9, 49. https://doi.org/10.1186/s13072-016-0100-6 Patel, L. A., Cao, Y., Mendenhall, E. M., Benner, C., & Goren, A. (2024). The Wild West of spike-in normalization. Nature biotechnology, 42(9), 1343–1349. https://doi.org/10.1038/s41587-024-02377-y Ben-Yair, R., Butty, V. L., Busby, M., Qiu, Y., Levine, S. S., Goren, A., Boyer, L. A., Burns, C. G., & Burns, C. E. (2019). H3K27me3-mediated silencing of structural genes is required for zebrafish heart regeneration. Development (Cambridge, England), 146(19), dev178632. https://doi.org/10.1242/dev.178632 Patel, L., Cao, Y., Xu, T., Modolo, E., Dishon, T., Zhang, L., Mendenhall, E., Heinz, S., Simon, I., Benner, C., & Goren, A. (2025). Improved spike-in normalization clarifies the relationship between active histone modifications and transcription. Genomics. https://doi.org/10.1101/2025.11.25.690627 Xu, T., Wang, J., Shin, Y., Cao, Y., Zhang, L., Modolo, E., Dishon, T., Fisher, J., Norton, M., Fry, C. J., Farjoun, Y., Mendenhall, E., Heinz, S., Benner, C., & Goren, A. (2026). Multiplexed measurements of protein-protein interactions and protein abundance across cellular conditions using Prod&PQ-seq. Genomics. https://doi.org/10.64898/2026.01.01.697286 Related Episodes Taking ChIP from Yeast to ENCODE to Enable Genome-Wide Regulatory Protein Mapping (Peggy Farnham) Comparing CUT&Tag to ENCODE ChIP-Seq in Alzheimer's Disease Samples (Sarah Marzi) Chromatin Profiling: From ChIP to CUT&RUN, CUT&Tag and CUTAC (Steven Henikoff) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com
In this episode, Howard Farran welcomes back Dr. Densen Cao — physicist, prolific inventor, and founder and CEO of CAO Group and AMD Lasers — for his first return to the show in eight years. Mentored early in his career by Dr. Gordon and Dr. Rella Christensen, Dr. Cao has spent decades developing disruptive dental technologies at the intersection of physics, materials science, and clinical dentistry. The heart of the conversation is his newly released LEAP procedure (Laser Endodontic Ablation Procedure), unveiled at AAE 2026 after five years of FDA review and more than 100 U.S. cases. Dr. Cao explains why disinfection — not obturation — is the true key to root canal success, and how LEAP uses a low-energy diode laser to ablate residual tissue and bacteria, paired with a proprietary LEAP solution of chlorhexidine and ethanol to reach the fins and side canals. The result, he says, is a five-nines (99.999%) bacteria reduction achieved in live patients, with an independent clinical study by Dr. Rella Christensen now underway. The discussion then moves to prevention, where Dr. Cao introduces his caries risk testing strips — which measure salivary pH and buffer capacity with a simple lick — and "Cavity Fighter" mints designed to neutralize acid and remineralize enamel during the critical window after eating. Along the way, Howard and Dr. Cao explore why a small percentage of people never get cavities, the impact of vaping and dry mouth on caries risk, the physics of curing lights, and the history behind AMD Lasers. The episode closes with Dr. Cao's reflections on COVID and disinfection, the future of AI in dentistry, and what a lifetime in physics has taught him about trusting science and data above all. Episode #1711 : Dentistry Uncensored with Howard Farran, Howard welcomes back his friend Dr. Densen Cao — physicist, inventor, and founder & CEO of CAO Group and AMD Lasers — eight years after his first appearance. From a groundbreaking new laser root canal disinfection procedure (LEAP) that just earned FDA clearance, to caries risk strips and "Cavity Fighter" mints that could change how we prevent decay, Dr. Cao shares what happens when a physicist tackles dentistry's oldest problems.
- Chủ tịch Quốc hội Trần Thanh Mẫn tiếp Tổng Chưởng lý Malaysia đang có chuyến thăm và làm việc với Viện Kiểm sát nhân dân tối cao Việt Nam.- Phường Bình Quới, thành phố HCM ra mắt mô hình “Điểm truy cập số và thủ tục hành chính trực tuyến” tại địa bàn khu dân cư.- Đại học Bách khoa Hà Nội công bố điểm xét tuyển tài năng 2026, đáng chú ý 53 thí sinh đạt điểm tuyệt đối 100/100.- Cao tốc Cam Lộ - La Sơn tạm dừng lưu thông ban đêm để phục vụ thi công mở rộng tuyến lên 4 làn xe.- Giá dầu bật tăng sau vụ tàu chở dầu bị tấn công tại eo biển Hormuz - tuyến vận tải dầu chiến chiến lược của thế giới.+ Hơn 1.000 trường học tại Anh gián đoạn hoạt động do nắng nóng. Trong khi đó, Khu tự trị dân tộc Choang Quảng Tây (Trung Quốc) phải nâng cảnh báo lũ lên mức đỏ do mưa lớn kéo dài.
Is é amárach, an chéad lá de mhí Iúil, an spriocdháta do dhaltaí lena n-intinn a athrú maidir leis na roghanna atá déanta acu ar chóras iontrála an CAO. Labhair Susan linn faoin spriocdháta seo agus chuir sí rud beag comhairle ar dhaoine faoina gcuid roghanna.
The CAO change of mind closes at 5pm on the 1st of July, meaning students must decide on their final preferences. Guidance counsellor and columnist with the Irish Times Brian Mooney joined Anton to give last minute advice.
Mới đây một lễ tang long trọng diễn ra tại sân vận động Criket Melbourne, để tiễn biệt ông Neale Daniher, người đấu tranh cho căn bệnh thoái hóa thần kinh vận động (MND). Cuộc chiến kéo dài 13 năm của Daniher với căn bệnh mà ông gọi là “The Beast hay Con thú", nổi tiếng nhờ chiến dịch gây quỹ và nâng cao nhận thức cho nghiên cứu y học về MND của Neale. Bác sĩ Michael Dũng Cao tại Sydney cho biết thêm về bệnh nầy, vốn thường xuất hiện ở các bậc cao niên.
Đề xuất giảm tuổi hưởng trợ cấp hưu trí xã hội xuống 70 thay vì 75 như hiện nay. Từ 1/7, lương cơ sở tăng lên 2,53 triệu đồng một tháng nhưng một cuộc khảo sát tìm thấy 54,3% người lao động cho biết tiền lương, thu nhập hiện chỉ vừa đủ chi tiêu cơ bản của gia đình. Quyền Bộ trưởng Hải quân Hoa Kỳ Hùng Cao viếng thăm Việt Nam.
Tonight we welcomed Melanie Brown and her daughter, Rebekah, to the show. Melanie, CAO and co-owner of Prairie Sky Recovery Centre and a Registered Social Worker, shared how her lived experience in addiction and recovery has helped shape both her personal journey and her life's work. Joined by Rebekah, an emerging voice in the recovery community, the conversation highlighted the importance of carrying the message of hope to the next generation. A longtime friend of the show, Prairie Sky Recovery Centre continues to make a lasting impact through the legacy of founder Ardyth Wilson and its commitment to helping people find lasting recovery.
Listener discretion is advised! References: Buttner & Arlanger. (May 3, 2022). ST depression does not localise. Available: https://litfl.com/st-depression-does-not-localise/ Cannon, J. W., Khan, M. A., Raja, A. S., et al. (2017). Damage control resuscitation in patients with severe traumatic hemorrhage. Journal of Trauma and Acute Care Surgery, 82, 605-617. Kabra, R., Acharya, S., Kamat, S., & Kumar, S. (2022). ST-Segment Elevation in Lead aVR With Global ST-Segment Depression: Never Neglect Left Main Coronary Artery (LMCA) Occlusion. Cureus. Lee, G.-K., Hsieh, Y.-P., Hsu, S.-W., Lan, S.-J., & Soni, K. (2019). Value of ST‐segment change in lead aVR in diagnosing left main disease in Non‐ST‐elevation acute coronary syndrome—A meta‐analysis. Annals of Noninvasive Electrocardiology, 24. Morrison, C. A., Carrick, M. M., Norman, M. A., et al. (2011). Hypotensive Resuscitation Strategy Reduces Transfusion Requirements and Severe Postoperative Coagulopathy in Trauma Patients With Hemorrhagic Shock: Preliminary Results of a Randomized Controlled Trial. Journal of Trauma: Injury, Infection & Critical Care, 70, 652-663. Rossaint, R., Afshari, A., Bouillon, B., et al. (2023). The European guideline on management of major bleeding and coagulopathy following trauma: sixth edition. Critical Care, 27. Tamura, A. (2014). Significance of lead aVR in acute coronary syndrome. World Journal of Cardiology, 6(7), 630. Uthamalingam, S., Zheng, H., Leavitt, M., Pomerantsev, E., Ahmado, I., Gurm, G. S., & Gewirtz, H. (2011). Exercise-Induced ST-Segment Elevation in ECG Lead aVR Is a Useful Indicator of Significant Left Main or Ostial LAD Coronary Artery Stenosis. JACC: Cardiovascular Imaging, 4, 176–186. Weymouth, W., Long, B., Koyfman, A., & Winckler, C. (2019). Whole Blood in Trauma: A Review for Emergency Clinicians. The Journal of Emergency Medicine, 56, 491-498. Wang, A., Singh, V., Duan, Y., Su, X., Su, H., Zhang, M., & Cao, Y. (2020). Prognostic implications of ST‐segment elevation in lead aVR in patients with acute coronary syndrome: A meta‐analysis. Annals of Noninvasive Electrocardiology, 26.
Do you think AI will have an impact on science? You are wrong. It will not–it already does. The annual International Conference on Information Systems received over 1,000 more paper submissions this year. Our main journals report a 20%, 40%, or even 100% increase in submission numbers. This could be great if these papers were good, if we simply saw more and better research being produced. Problem is: We don't. What we see is an AI slop tsunami of less readable papers, hastily produced, with marginal insights if any. How should we handle this situation? We discuss a few possible levers on the supply and demand side of research that we as a field could implement. References Gartenberg, C., Hasan, S., Murray, A., & Pierce, L. (2026). More Versus Better: Artificial Intelligence, Incentives, and the Emerging Crisis in Peer Review. Organization Science, 37(3), https://doi.org/10.1287/orsc.2026.ed.v37.n3. Ho, S. Y., Recker, J., Tan, C.-W., Vance, A., & Zhang, H. (2023). MISQ Special Issue on Registered Reports. MIS Quarterly, https://misq.umn.edu/call_for_papers/registered-reports. Liang, W., Zhang, Y., Cao, H., Wang, B., Ding, D. Y., Yang, X., Vodrahalli, K., He, S., Smith, D. S., Yin, Y., McFarland, D. A., & Zou, J. (2024). Can Large Language Models Provide Useful Feedback on Research Papers? A Large-Scale Empirical Analysis. NEJM AI, 1(8). https://doi.org/10.1056/AIoa240019 Saunders, C. (2005). Editor's Comments: Looking for Diamond Cutters. MIS Quarterly, 29(1), iii–viii. Tyner, A. H., Abatayo, A. L., Daley, M., . . . Errington, T. M. (2026). Investigating the Replicability of the Social and Behavioural Sciences. Nature, 652(8108), 143–150. Dennis, A. R., Valacich, J. S., Fuller, M. A., & Schneider, C. (2006). Research Standards for Promotion and Tenure in Information Systems. MIS Quarterly, 30(1), 1–12.
Taking the non-traditional path to leadership does not necessarily mean failure – sometimes, it is exactly what you need to unleash your fullest potential. Jack McCullough sits down with Kate Gulliver, CFO and CAO of Wayfair, who shares the story of her unconventional yet inspiring road to a C-level position. She talks about the most valuable lessons she learned from her mentors, how she maintains a work-life balance despite her hectic schedule, and how she keeps a meaningful relationship with her CEO. Kate also discusses the biggest advantages of Wayfair's technology-driven asset-light marketplace model that connects consumers with suppliers at scale.
In this episode Divya speaks with Rachel Carmenta, Associate Professor of Climate Change and International Development at the University of East Anglia. They discuss Rachel's recent work on the poverty–biodiversity loss association (PBLA) and the idea of connected conservation. In this scholarship, Rachel and her colleagues critically examine how mainstream conservation narratives have often framed poor and rural communities as drivers of biodiversity decline, while overlooking the larger structural forces, such as extractive industries, unsustainable patterns of consumption, and unequal political and economic systems, that are central to environmental degradation and biodiversity loss. They also discuss how poverty is often reduced to income deprivation and how that framing has made conservation and development programs to focus heavily on cash-based incentives and payment schemes. Rachel argues that poverty is way more than income deprivation; instead, it must be understood as multidimensional, encompassing wellbeing, dignity, health, education, security, and access to social services. This broader understanding challenges narrow approaches to both poverty alleviation and conservation governance. Another important theme in their discussion is connected conservation, which emphasizes the interconnected relationships between people, ecosystems, livelihoods, cultural practices, and local knowledge systems, rather than viewing conservation and human wellbeing as separate or competing goals. In this context, Rachel reflects on biocultural conservation and the importance of recognizing the ways communities live with, care for, and understand their environments and what these relationships can teach us about more just and meaningful approaches to conservation in a rapidly changing world. References: Carmenta, R., Lima, M.G.B., Choiruzzad, S.A., Dawson, N., Estrada-Carmona, N., Hicks, C., Kallis, G., Nana, E., Killick, E., Lees, A. and Martin, A., 2025. Unveiling pervasive assumptions: moving beyond the poverty-biodiversity loss association in conservation. Current Opinion in Environmental Sustainability, 74, p.101537. Tebboth, M.G., Carmenta, R., Minas, A., Adelekan, A., Cao, X., Fullonton, A., Kinally, C., Cataldo, N.L., Mander, S. and Shelton, C., 2025. The ‘how'of transformation: Principles for a justice-centered response to the climate and biodiversity crises. Environment: Science and Policy for Sustainable Development, 67(3), pp.7-23. Carmenta, R., Barlow, J., Lima, M.G.B., Berenguer, E., Choiruzzad, S., Estrada-Carmona, N., França, F., Kallis, G., Killick, E., Lees, A. and Martin, A., 2023. Connected Conservation: Rethinking conservation for a telecoupled world. Biological Conservation, 282, p.110047. Lapola, D.M., Pinho, P., Barlow, J., Aragão, L.E., Berenguer, E., Carmenta, R., Liddy, H.M., Seixas, H., Silva, C.V., Silva-Junior, C.H. and Alencar, A.A., 2023. The drivers and impacts of Amazon forest degradation. Science, 379(6630), pp. 8622. Carmenta, R., Zaehringer, J.G., Balvanera, P., Betley, E., Dawson, N.M., Estrada‐Carmona, N., Forster, J., Hoelle, J., Lliso, B., Llopis, J.C. and Menon, A., 2023. Exploring the relationship between plural values of nature, human well‐being, and conservation and development intervention: Why it matters and how to do it?. People and nature, 5(6), pp.1720-1738.
Tony Katz and Fingers Malloy light up the CAO Arcana Stokk Belicoso, a limited-edition 6.5x52 cigar with a Connecticut Broadleaf wrapper, Nicaraguan binder, and a distinctive filler blend that includes Cyprian Latakia pipe tobacco. The guys talk through the cigar’s odd-looking band, excellent draw, near-perfect burn, and the challenge of pinning down a flavor profile that seems to move between pepper, wood, tea, and a smoky note that keeps getting more interesting as the cigar develops. They also spend time digging into what makes a cigar worth revisiting, why construction matters just as much as flavor, and whether this CAO earns a spot in the humidor at around $13 a stick. Also in this Happy Hour episode: another round of Gas Station Finds with Pop Daddy Birthday Cake Popcorn, which somehow turns out to be both gimmicky and surprisingly good, plus talk about family-farm popcorn, sweet snack regret, and how close a man can get to accidentally eating an entire bag. It’s cigars, snack food, palate talk, and the completely unnecessary honesty that makes Eat, Drink, Smoke Happy Hour what it is. Find everything at EatDrinkSmokeShow.comSee omnystudio.com/listener for privacy information.