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With the increasing incidence of colorectal cancer in those less than 50 years of age, one must wonder how many patients present with a Stage IV diagnosis. Take a deep dive with us discussing the management of metastatic colorectal cancer by joining our team and guests, Drs. Cathy Eng, Michael D'Angelica, and Nina Sanford.Hosts: - Dr. Janet Alvarez - General Surgery Resident at New York Medical College/Metropolitan Hospital Center- Dr. Wini Zambare – General Surgery Resident at Weill Cornell Medical Center/New York Presbyterian- Dr. Philip Bauer, Assistant Professor of Surgery, Division of Colon and Rectal Surgery, The Ohio State University Wexner Medical Center, Arthur G. James Cancer Hospital-  Dr. J. Joshua Smith MD, PhD, Chair, Department of Colon and Rectal Surgery at MD Anderson Cancer Center Guest Speakers:- Dr. Michael D'Angelica MD, FACS – Hepatopancreatobiliary Surgery, Memorial Sloan Kettering Cancer Center, Enid A. Haupt Chair in Surgery, Vice Chair, Education- Dr. Cathy Eng MD, FACP - Division of Hematology and Oncology, Vanderbilt-Ingram Cancer Center, David H. Johnson Endowed Chair in Surgical and Medical Oncology, Professor of Medicine, Hematology and Oncology, VICC Associate Director for Strategic Relations and Research Partnerships, Executive Director, Young Adult Cancers Program - Dr. Nina Sanford, MD – Radiation Oncology, UT Southwestern Medical Center, Chief of Gastrointestinal Radiation Oncology Service, Associate Professor Learning Objectives:1.     Review the epidemiology, prognosis, and common metastatic patterns of metastatic colorectal cancer (mCRC).2.     Discuss the role of systemic chemotherapy and targeted therapies in the first- and subsequent-line treatment of mCRC, including the impact of molecular biomarkers such as MSI/MMR, RAS, BRAF, and HER2.3.     Evaluate the indications and timing of surgical and locoregional therapies for metastatic colorectal cancer, particularly in patients with liver-limited or oligometastatic disease.4.     Describe the multidisciplinary management of mCRC, including the roles of radiation therapy, systemic therapy sequencing, and palliative interventions to optimize outcomes and quality of life.References:Singh, M., Morris, V. K., Bandey, I. N., Hong, D. S. & Kopetz, S. Advancements in combining targeted therapy and immunotherapy for colorectal cancer. Trends Cancer 10, 598–609 (2024). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/38821852/Napolitano, S. et al. BRAFV600E mutant metastatic colorectal cancer: Current advances in personalized treatment and future perspectives. Cancer Treat. Rev. 134, (2025). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40009904/Ciardiello, F. et al. Clinical management of metastatic colorectal cancer in the era of precision medicine. CA. Cancer J. Clin. 72, 372–401 (2022). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/35472088/Kim, S. Y. & Kim, T. W. Current challenges in the implementation of precision oncology for the management of metastatic colorectal cancer. ESMO Open 5, e000634 (2020). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/32188714/Biller, L. H. & Schrag, D. Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review. JAMA 325, 669–685 (2021). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/33591350/Smith, J. J. et al. Genomic stratification beyond Ras/B-Raf in colorectal liver metastasis patients treated with hepatic arterial infusion. Cancer Med. 8, 6538–6548 (2019). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/31503397/Saadat, L. V. et al. Hepatic Artery Infusion Chemotherapy Compared to Transarterial Radioembolization For Unresectable Colorectal Liver Metastases. Ann. Surg. 10.1097/SLA.0000000000006851 doi:10.1097/SLA.0000000000006851. PubMed Link: https://pubmed.ncbi.nlm.nih.gov/?term=10.1097/SLA.0000000000006851 (Linked via DOI search as the direct PMID is still indexing)Xiao, A. & Fakih, M. KRAS G12C Inhibitors in the Treatment of Metastatic Colorectal Cancer. Clin. Colorectal Cancer 23, 199–206 (2024). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/38825433/André, T. et al. Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer. N. Engl. J. Med. 383, 2207–2218 (2020). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/33264544/Morris, V. K. et al. Treatment of Metastatic Colorectal Cancer: ASCO Guideline. J. Clin. Oncol. 41, 678–700 (2023). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/36252154/Xu, Z. et al. Treatments for Stage IV Colon Cancer and Overall Survival. J. Surg. Res. 242, 47–54 (2019). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/31071604/Smith, J. J. & D'Angelica, M. I. Surgical Management of Hepatic Metastases of Colorectal Cancer. Hematol. Oncol. Clin. North Am. 29, 61–84 (2015). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/25475573/Strickler, J. H. et al. Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study. Lancet Oncol. 24, 496–508 (2023). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/37142372/Kruijssen, D. E. W. van der et al. Upfront resection versus no resection of the primary tumor in patients with synchronous metastatic colorectal cancer: the randomized phase III CAIRO4 study conducted by the Dutch Colorectal Cancer Group and the Danish Colorectal Cancer Group. Ann. Oncol. 35, 769–779 (2024). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/38852675/Hitchcock, K. E., Romesser, P. B. & Miller, E. D. Local Therapies in Advanced Colorectal Cancer. Hematol. Oncol. Clin. North Am. 36, 553–567 (2022). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/35562258/Hitchcock, K. E. et al. Alliance for clinical trials in Oncology (Alliance) trial A022101/NRG-GI009: a pragmatic randomized phase III trial evaluating total ablative therapy for patients with limited metastatic colorectal cancer: evaluating radiation, ablation, and surgery (ERASur). BMC Cancer 24, 201 (2024). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/38350888/Adam, R. et al. Liver transplantation plus chemotherapy versus chemotherapy alone in patients with permanently unresectable colorectal liver metastases (TransMet): results from a multicentre, open-label, prospective, randomised controlled trial. The Lancet 404, 1107–1118 (2024). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/39306468/Elez, E. et al. Encorafenib, Cetuximab, and mFOLFOX6 in BRAF-Mutated Colorectal Cancer. N. Engl. J. Med. 392, 2425–2437 (2025). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40444708/***Fellowship Application Link: https://forms.gle/QSUrR2GWHDZ1MmWC6Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium:General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

In this episode, we are going to take a closer look at Vancomycin, one of the most widely used antibiotics in the hospital setting and a medication that pharmacists frequently monitor. Vancomycin is a glycopeptide antibiotic primarily used to treat serious gram-positive infections, including those caused by Methicillin-resistant Staphylococcus aureus (MRSA). Its mechanism of action involves inhibiting bacterial cell wall synthesis by binding to the D-alanine–D-alanine portion of peptidoglycan precursors, which ultimately prevents the bacteria from forming a stable cell wall. Clinically, vancomycin is commonly used for infections such as bacteremia, endocarditis, osteomyelitis, and severe skin and soft tissue infections when resistant gram-positive organisms are suspected. One of the most important aspects of vancomycin therapy is therapeutic drug monitoring, as maintaining appropriate exposure is critical for both efficacy and safety. Current practice often focuses on achieving target AUC-to-MIC ratios rather than relying solely on trough levels. Pharmacists also play an important role in adjusting doses based on renal function and monitoring for adverse effects. Two key safety concerns with vancomycin are nephrotoxicity and vancomycin infusion-related reactions such as “red man syndrome,” which is characterized by flushing, rash, and hypotension if the medication is infused too rapidly. Throughout this episode, we will review the pharmacology, monitoring parameters, and clinical pearls that healthcare professionals should understand when managing patients receiving vancomycin therapy. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources! NAPLEX Study Materials BCPS Study Materials BCACP Study Materials BCGP Study Materials BCMTMS Study Materials Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101

Our guest today is Kevin Washington, a former Notre Dame linebacker who is currently an associate AD with Baylor University in Waco, TX."Get in the Game" is part of the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sports Spectrum Podcast Network⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Sign up for our Sports Spectrum Magazine and receive 15% off a 1-year subscription by using the code PODCAST15⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://SportsSpectrum.com/magazine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Do you know Christ personally? Click ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to learn how you can commit your life to Him."Get in the Game" is part of the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sports Spectrum Podcast Network⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

SEG 14: Grant Newsham discusses South Korea's reluctance to assist in the Strait of Hormuz. He characterizes the current administration as ideologically pro-China and skeptical of US alliances, potentially undermining regional security cooperation against common global threats. (15)1950 Korea

Exploring Bogus oil prices Hold cow – look at what Gemini and JSD can do… Markets needed good news – Correlation high Fed on hold? PLUS we are now on Spotify and Amazon Music/Podcasts! Click HERE for Show Notes and Links DHUnplugged is now streaming live - with listener chat. Click on link on the right sidebar. Love the Show? Then how about a Donation? Follow John C. Dvorak on Twitter Follow Andrew Horowitz on Twitter   Warm-Up - Bogus Oil Prices - Look at what Gemini and JSD can do... - Markets needed good news - Correlation high - Fed on hold? - JCD LIMERICK! Markets - Did we just correct? - Inflation - Eco that matters - Manipulation in Oil - Land? John Dvorak Jr. - Guest  - UPDATE ON JCD - AH Spoke with JCD Saturday.... Oil Prices - Bogus? - The price of oil in the middle east is at $140 for its land-locked price, but ocean traveling oil is at $100. - Sort, of, opposite of what you'd expect? - But, then there's been active conversation and warning about manipulating oil futures to manage the situation. - Oil in Backwardation across the spectrum. (Current price of oil contract is $95 and December contract is $75) Oil Prices may be BOGUS - But What About Gas? Gas Prices More Manipulation - The Trump administration has discussed trading in the oil futures market as a strategy to help curb surging crude prices amid the war in Iran, Interior Secretary Doug Burgum said. - US would just sell future contracts and then deliver at those prices at the end of the contract date. (SPR/Venezuela?) - Not sure how markets will take an intervention like that. - Remember when short selling was banned on Financials back in the 2008 ----Stock prices continued to fall during the ban and tended to stabilize only after it was lifted, suggesting the ban did not stop the decline. ------ Seems that when government intervenes in free markets they can set off more panic as the optics make it look even worse. ---- AND- Russian Oil sanctions partially removed Inflation and ECO - PCE Prices stay elevated - GDP rose at a seasonally and inflation-adjusted annual rate of just 0.7% in the fourth quarter, according to a Commerce Department revision Friday. - The first revision of the GDP reading was a sharp step down from the previous estimate of 1.4% and well below the Dow Jones consensus forecast for 1.5%. - The core PCE inflation rose 0.4% in January and 3.1% on a 12-month basis. The ex-food and energy reading was 0.1 percentage point higher than December. Eco Table Oil Models...Very Cool - JSD - Explain - https://gemini.google.com/share/d1427a61a804 Department of Defense, err War, is hiring - The Pentagon is hiring financial 'defense', or is that a financial warfare unit? - This may mean we're beginning to really adopt "Unrestricted Warfare (???) ----- ie: The Chinese strategy where the warfare model is extended to include social engineering, illicit trade, and finance operations. - Isn't this already in play? Tariffs, Straits of Hormuz, Asset Seizure (Russian Yachts), Venezuelan Oil???? --- This is why Quantum is in play too...(offense and defense) Did you know? - 30% of Helium production comes from Qatar - Qatar helium production stopped back on March 2nd, and is ~30% of all helium globally - South Korea depends almost entirely on helium from the strait of Hormuz, with 65% from Qatar specifically -  Semiconductor manufacturing - - Wafer/equipment cooling — High thermal conductivity removes heat fast during lithography, etching, deposition, and other steps; critical for precise temp control and smaller chip nodes (no good substitutes). - - Inert purging & atmospheres — Chemically inert; flushes systems, prevents unwanted reactions in annealing, deposition, or vacuum chambers. -- - Plasma processes — Acts as carrier, diluent, or purge gas in plasma etching for precise circuit patterning. - - Leak detection — Tiny atoms detect micro-leaks in tools, pipelines, and vacuum systems to ensure reliability. - - Backside wafer cooling — Delivers stable cooling to silicon wafers in advanced fabs. INDIA! Running out of Gas - Does it matter? - India maintains only a 25 day reserve of oil - Good news for them that they use coal for electricity generation, and only use oil for transportation - BUT BUT BUT, What about getting goods from one place to another in India? -- FWIW - coal prices up 19% YTD in India Back to this... - AI not causing job losses - WHAT ABOUT META? - Meta's stock climbed after Reuters reported the social media giant is planning to lay off over 20% of its 79,000 employees to balance AI-related spending. Drone Warfare - New Warfare fought like games - Ender's Game Movie - Length: 3.5 meters (about 11.5 feet) Wingspan: 2.5 meters (about 8.2 feet) Weight (total takeoff/mass): Approximately 200 kg (around 440 pounds) Warhead/payload: Typically 40–50 kg explosive (some variants up to 90 kg with reduced fuel/range) --- Usage ~ 2,000 per day in Iran an peak of 10,000 per day in Ukraine/Russia Gaming Industry - DOA? See above - no wonder why - it is IRL now - Q1 continues sharp decline in video game sales - Older gamers: new AAA titles heavily cannibalized by old games - Gen Z & Alpha mostly play only Roblox (144M DAU), Fortnite (60M DAU), or Minecraft (11M DAU) - Young gamers rarely buy new AAA titles or consoles - Industry “growth” driven purely by subscriptions & upsells — no real sales increase - Hardware far below peaks: PS2 sold 160M, Nintendo DS 154M vs Switch 2 only 17M (original Switch lifetime 114M) - AI failing to cut costs for big studios — Roblox capturing all the upside - Roblox launches Incubator & Jumpstart programs for kids using AI “vibe-coding” to chase millionaire status INTERACTIVE BROKERS Check this out and find out more at: http://www.interactivebrokers.com/ Target Earnings - Target posted another quarter of falling revenue and customer traffic at its stores, though its shares rose as the retailer's earnings beat estimates and it said it is poised to end its sales slump. -  Earnings per share: $2.44 adjusted vs. $2.16 expected - Revenue: $30.45 billion vs. $30.48 billion expected - Target said it expects full-year adjusted earnings per share to range from $7.50 to $8.50. Its adjusted earnings per share for the most recent full year were $7.57. - Shares up 7% in a piss poor tape     Love the Show? Then how about a Donation? THE CLOSEST TO THE PIN for CATERPILLAR Winners will be getting great stuff like the new "OFFICIAL" DHUnplugged Shirt!     FED AND CRYPTO LIMERICKS There is a tech pundit whose name be John, Whose sharp takes went late into dawn. He hit pause for some care, But with grit (and repair), Soon he'll be back oh so steady and strong. See this week's stock picks HERE Follow John C. Dvorak on Twitter Follow Andrew Horowitz on Twitter

Listen and subscribe to Money Making Conversations on iHeartRadio, Apple Podcasts, Spotify, www.moneymakingconversations.com/subscribe/ or wherever you listen to podcasts. New Money Making Conversations episodes drop daily. I want to alert you, so you don’t miss out on expert analysis and insider perspectives from my guests who provide tips that can help you uplift the community, improve your financial planning, motivation, or advice on how to be a successful entrepreneur. Keep winning! Two-time Emmy and Three-time NAACP Image Award-winning, television Executive Producer Rushion McDonald interviewed Natalie Southwell. Founder and CEO of The Essence of a Woman, LLC, a female empowerment agency dedicated to helping high‑achieving women rise with confidence, courage, clarity, and faith-driven purpose. The conversation explores: How women can overcome fear, trauma, and misaligned life decisions The role of faith, purpose, and intentionality in decision-making Her frameworks: PAIN and REAL Her personal journey to launching The Essence of a Woman How she guides women across generations—including students, early professionals, mid-career women, and women 50+—toward alignment and leadership.

On this episode of the Woodard Report podcast, Heather and Joe discuss the growing threat of AI-powered financial scams and practical steps firms can take to protect themselves and their clients. They also explore major shifts in the accounting technology space, including platform-driven CAS models, AI misconceptions, and evolving firm strategies. Current events — Financial scams on the rise and they are getting better. How can we protect ourselves? Xendoo to purchase the Infinite platform from Botkeeper TV/Movie quote of the week — Portlandia A Knight of the 7 Kingdoms Excellent things we learned — More than a Glitch: Confronting Race, Gender, and Ability Bias in Tech The Productivity Project: Accomplishing More by Managing Your Time, Attention, and Energy Member spotlight — Melissa Honan, Profitable Painter CPA The Woodard Report article of the week — Inside Intuit's Career Pipeline Program for Accountants Thank you to our show sponsor, Woodard! The Woodard membership program will help you build your ideal practice with our coaching, education, community, and resources. We'll get you there with strategic direction from experienced pros, access to skill building and resources, and a community to continually inspire your practice's transformation. Learn more about the show and our sponsors at Woodard.com/podcast

Dr Lajos Pusztai from Yale Cancer Center in New Haven, Connecticut, discusses recent developments with circulating tumor DNA assays in the management of breast cancer.CME information and select publications here.

Brandon Sedloff sits down with John Atwater to explore the evolution of Prime Finance and the broader dynamics shaping real estate private credit. John shares the story of launching Prime during the Savings and Loan crisis and how periods of market stress often create the best opportunities for disciplined lenders. The conversation traces the growth of Prime into a major platform across CMBS, origination, and special situations while examining how lending businesses are ultimately built around relationships and service. Along the way, they discuss how today's private credit market compares to past cycles and where the most compelling opportunities may emerge over the next several years. They discuss: • John Atwater's career path and the founding of Prime during the Savings and Loan crisis • Why market dislocations often create the best investment opportunities for lenders • How Prime built scale across CMBS, origination, and special situations strategies • Key differences between real estate private credit and corporate private credit markets • Current private credit market dynamics and the outlook for the next five years Links: John on LinkedIn - https://www.linkedin.com/in/john-atwater-89ba1b126/ Prime - https://primefinance.com/ Brandon on LinkedIn - ⁠https://www.linkedin.com/in/bsedloff/⁠ Juniper Square - ⁠https://www.junipersquare.com/⁠ Topics: (00:00:00) - Intro (00:02:34) - John Atwater's career and background (00:12:39) - Starting prime during the S&L crisis (00:17:28) - Why crisis creates opportunity (00:22:42) - Building the Prime finance platform (00:28:04) - Special situations vs origination (00:33:12) - Real estate credit vs corporate private credit (00:40:08) - Current private credit market dynamics (00:43:31) - Outlook for next 5 years (00:50:20) - How to reach prime finance (00:50:42) - Closing remarks

In this episode of More Faith More Life, Steve Gray explores the historical roots of America's Judeo-Christian values and why the current crisis facing the nation is not merely political, but spiritual. From the Continental Congress calling citizens to repentance in 1775 to the adoption of “In God We Trust” as the national motto in 1956, this episode looks at how faith influenced America's beginnings.Using the biblical story of Elisha purifying contaminated water with salt, Steve explains why Jesus called believers the salt of the earth and what happens when the church loses its influence. Key Takeaways:America was founded on Judeo-Christian values, which were crucial in shaping its foundational documents and laws.Current societal shifts introduce new religious and political ideas that diverge from the nation's historical roots.The challenges facing America are primarily spiritual in nature, not merely political.The church plays a critical role, likened to salt, in preserving and nurturing the spiritual health of the nation.A call to action for spiritual renewal and revival within American society to maintain its foundational integrity.Looking for more? Join our More Faith More Life community: https://morefaithmorelife.com

The United States takes on Venezuela in the championship game of the World Baseball Classic. The Venezuela team is playing in a WBC final for the first time in their country's history. Geoff Bennett discussed the tournament with Howard Bryant, author of multiple books, including most recently, "Kings and Pawns: Jackie Robinson and Paul Robeson in America." PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

As the war with Iran continues, businesses and shipping companies are growing increasingly concerned about potential disruptions to the global supply chain. So far, major ports in the U.S. are operating normally, but there are real questions about how long that stability can hold. Geoff Bennett discussed what this could mean for global trade with Gene Seroka of the Port of Los Angeles. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

For perspective on Israel's killing of one of Iran's most senior leaders, Ali Larijani, and the head of Iran's Basij internal security force, Amna Nawaz spoke with Alan Eyre and Joel Rayburn. Eyre was part of the Obama administration's negotiating team for the nuclear deal with Iran and is now at the Middle East Institute. Rayburn is a retired Army colonel and is now at the Hudson Institute. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

To discuss Joe Kent's comments about the Iran war and what his resignation says about the intelligence community, Nick Schifrin spoke with Nick Rasmussen. He directed the National Counterterrorism Center under the Obama administration. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

Joe Kent, the former director of the United States National Counterterrorism Center, resigned from that position in protest on Tuesday. Kent refuted President Trump's statements that Iran presented an imminent threat, and said the war was in Israel's interest, but not the United States'. White House correspondent Liz Landers reports. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

Iranian officials confirmed that Ali Larijani, a fixture of Iran's regime for decades, was killed by an Israeli airstrike that also killed another top security official. And for the first time in years, a senior U.S. government official has resigned in protest. Nick Schifrin reports. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

Support the show: http://www.newcountry963.com/hawkeyeinthemorningSee omnystudio.com/listener for privacy information.

2. The debate continues with a comparison of Emperor Trump to Nero and Claudius, questioning if his current crisis is a result of bad luck or hubris. While Claudius favored low-risk, calculated campaigns, Trump's offensive is characterized as a "rash and incalculably risky gambit" that mirrors strategic failures in Ukraine. This conflict has solidified the Russia-Chinabond and left Israel "naked and exposed" due to US failures. Germanicus argues that the US ignored the "weak points" of its own coalition, turning Gulf State bases into liabilities rather than security assets. Likening Trump's overconfidence to Hitler's before the invasion of Russia, the speakers suggest that the US has "got suckered" into a war it cannot win through air power alone. They conclude that the only rational path is to accept defeat and reorganize, as the Romans did when facing superior Persian cavalry. (2)1680 CONSTANTINOPLE

Is there anything better than pouring a glass of wine after putting the kids to bed and sitting down for a cozy, unfiltered “favorite things” girl chat? Avery shares the little things currently bringing her joy, from the homemade latte that gets her out of bed every morning to the skincare and beauty products that completely changed her routine. She also gets into her latest wellness obsessions, including red light therapy, regular facials, and the retinol that finally convinced her to join the anti-aging club. Cheers! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Navigating the Current Multifamily Market: Insights from Matt Frazier In this episode, Jake and Gino host Matt Frazier, founder and CEO of Jones Street Investment Partners, to discuss the nuances of the multifamily real estate landscape amid shifting market dynamics. Matt shares his journey, investment strategies, and predictions for the coming year, providing valuable lessons for both new and seasoned investors. Timestamps 00:00 - Introduction and guest background: 25+ years in real estate and finance 02:21 - Current state of the multifamily market and interest rate outlook 03:51 - The fundamental problem: capital deployment and investor psychology 05:39 - Matt's origin story: From venture capital to real estate 07:42 - Early deals: Boston triplexes and market evolution 09:11 - Transition from small assets to larger, institutional-scale properties 12:24 - The regional focus: Northeast's resilience and supply-demand fundamentals 14:14 - Investment criteria: Value-oriented strategies in changing environments 15:48 - How vintage and location influence value-add opportunities 17:55 - What defines true value in multifamily investments? 19:10 - Market risks: Supply constraints, regulatory hurdles, and volatility 20:54 - Rent growth and market dynamics: Northeast vs. Sunbelt 22:48 - Mistakes in dealing with bridge debt and deal selection 24:56 - Advice for new investors entering today's market 27:37 - Market diversity: Geographic reach from Maine to Virginia 28:23 - Secondary markets: Population thresholds and niche opportunities 30:37 - The psychology of investor appetite in smaller markets 33:33 - How investor psychology affects market segmentation and compression 36:42 - Market fundamentals: The importance of barriers to entry and supply constraints 37:17 - Building a scalable property management operation 39:49 - Challenges and opportunities in property management industry 42:37 - Emerging role of AI and technology in property operations 44:41 - Avoiding pitfalls: personnel and organizational mistakes 45:32 - Bold predictions for 2024: Market thaw and interest rate declines 47:07 - Connecting with Matt and closing remarks   Contact Matt Frazier: Jonesstreet.com Ready to dive into multifamily real estate? Start your journey at wheelbarrowprofits.com For more content and coaching, visit jakeandgino.com We're here to help create real estate entrepreneurs... About Jake & Gino: Jake & Gino are multifamily investors, operators, and owners who have created a vertically integrated real estate company. They control over $350M in assets under management. Connect with Jake & Gino here --> https://jakeandgino.com. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dan Anthony from WePayTheTariffs explains the recent Supreme Court decision that ruled certain tariffs illegal, how the refunds for affected importers will work, and what steps ecommerce owners should take moving forward. The Supreme Court recently struck down President Trump's tariffs.  And that means there's good news and bad news.  The good news is that you're likely going to be entitled to a full refund of any IEPPA tariffs you paid last year after the SCOTUS ruling. The other good news is that the CBP has been instructed to make the job of getting tariff refunds as simple as possible. The bad news is you're going to have to jump through a couple of hoops first. In today's episode, Dan Anthony from WePayTheTariffs is on to clear some of the confusion and skepticism about the refunds and the recent tariff increase that was announced after the Supreme Court passed their judgement.    Timestamps: 00:00 - The Supreme Court's ruling on tariffs 01:44 - What the ruling did and did not address 02:12 - What happens to tariff money? 03:42 - Differences in legal footing between Trump 1.0 and 2.0 tariffs 05:15 - Timeline for implementing new tariffs 09:46 - Current application rates of tariffs: 10% or 15% 10:10 - What you need to do to get tariff refunds 13:37 - The urgency of refunds and how delays cost the US government money 16:58 - The likelihood of refunds being issued 18:54 - Potential government objections to refunds and appeal possibilities 20:19 - Timeline and procedural steps for refund payments 22:04 - Windows to protest tariffs and how they apply here 23:37 - The role of legislative efforts and legal timelines for refunds 26:07 - WePayTheTariffs' mission and ongoing advocacy efforts 28:48 - How small importers can support the campaign and register for refunds Resources & Links: WePayTheTariffs.com — Join the movement to advocate for tariffs refunds CBP Refund Registration — Register for ACH refunds to ensure you receive your money Section 301 Trade Law — U.S. Trade Representative info Section 232 Steel & Aluminum Tariffs — Official documentation As always, if you have any questions or anything that you need help with, leave a comment down below if you're interested. Don't forget to leave us a review over on iTunes if you enjoy content like this. Happy selling and we'll talk to you soon!

Full Text of Readings Tuesday of the Fourth Week of Lent Lectionary: 245 The Saint of the day is Saint Patrick Saint Patrick's Story Legends about Saint Patrick abound; but truth is best served by our seeing two solid qualities in him: He was humble and he was courageous. The determination to accept suffering and success with equal indifference guided the life of God's instrument for winning most of Ireland for Christ. Details of his life are uncertain but his popularity has never wavered. Current research places his dates of birth and death a little later than earlier accounts. Patrick may have been born in Dunbarton, Scotland, Cumberland, England, or in northern Wales. He called himself both a Roman and a Briton. At 16, he and a large number of his father's slaves and vassals were captured by Irish raiders and sold as slaves in Ireland. Forced to work as a shepherd, he suffered greatly from hunger and cold. After six years Saint Patrick escaped, probably to France, and later returned to Britain at the age of 22. His captivity had meant spiritual conversion. He may have studied at Lerins, off the French coast; he spent years at Auxerre, France, and was consecrated bishop at the age of 43. His great desire was to proclaim the good news to the Irish. In a dream vision it seemed “all the children of Ireland from their mothers' wombs were stretching out their hands” to him. He understood the vision to be a call to do mission work in pagan Ireland. Despite opposition from those who felt his education had been defective, he was sent to carry out the task. He went to the west and north–where the faith had never been preached–obtained the protection of local kings, and made numerous converts. Because of the island's pagan background, Patrick was emphatic in encouraging widows to remain chaste and young women to consecrate their virginity to Christ. He ordained many priests, divided the country into dioceses, held Church councils, founded several monasteries and continually urged his people to greater holiness in Christ. He suffered much opposition from pagan druids and was criticized in both England and Ireland for the way he conducted his mission. In a relatively short time, the island had experienced deeply the Christian spirit, and was prepared to send out missionaries whose efforts were greatly responsible for Christianizing Europe. Patrick was a man of action, with little inclination toward learning. He had a rock-like belief in his vocation, in the cause he had espoused. He never doubted his direction because he understood that grace could guide him One of the few certainly authentic writings is his Confessio, above all an act of homage to God for having called Patrick, unworthy sinner, to the apostolate. There is hope rather than irony in the fact that his burial place is said to be in County Down in Northern Ireland, long the scene of strife and violence. Reflection What distinguishes Saint Patrick is the durability of his efforts. In the face of difficulty or strife, he maintained the faith. When one considers the state of Ireland when he began his mission work, the vast extent of his labors, and how the seeds he planted continued to grow and flourish, one can only admire the kind of man Patrick must have been. One of tireless faith and incredible stamina in bringing people to God. The holiness of a person is known only by the fruits of his or her work.Saint of the Day, Copyright Franciscan Media

Occasionally a new comic comes out that gets us so excited, we just have to talk about it. That was the feeling of Moonstar! We dive in and break down this first issue of Dani's solo mini series, spinning out of Ashley Allen's Magik solo run.  News - 1:02 |  Moonstar #1 - 7:13 |  Big Picture - 28:40 |  Thoughts & Questions - 30:49 |  Why Should I Buy? - 33:56 |  Thanks for joining us in our sixteenth episode of an evolving new format. We're trying out different ways to talk about things within continuity that excited us and we'd love to hear what you think! Leave us a review, send us a DM or shout from the telepathic rooftops! It's all greatly appreciated. 

I sat down with Sydney Huang from Human API to explore a completely novel concept—AI agents hiring humans, not the other way around. We dive into how they're solving the last mile problem for AI agents, why data collection is their first focus, and how you can actually get paid for contributing voice data and other tasks. Sydney shares her journey from buying Ethereum in 2017 to building Eclipse (a Solana VM L2 on Ethereum) to now creating an agent-native marketplace. We discuss the challenges of building a two-sided marketplace, the growing demand for AI training data, and why now is the perfect time to build in this space. KEY POINTS WITH TIMESTAMPS• [00:00] Introduction to Human API and the concept of AI agents hiring humans• [02:30] Sydney's journey from buying ETH in 2017 to working in VC to building in crypto full-time• [04:15] Eclipse explained: Building a Solana VM L2 on Ethereum and the modular blockchain thesis• [06:45] The last mile problem for AI agents and why human tasks are still needed• [09:20] How Human API differs from traditional workflow automation tools• [11:00] Current use cases: Conversational audio data collection for training voice AI• [14:30] Future expansion into health wearables data and other data types• [18:45] Why people are willing to work for AI agents and contribute data• [21:00] Building a better UX than Fiverr and Upwork with reputation systems• [25:15] The chicken-and-egg challenge of balancing supply and demand• [28:30] Why now is the perfect time to build in the AI data space• [31:00] Roadmap: App launch and making the agent experience seamless• [32:45] How to become a contributor at thehumanapi.comCONNECTHuman API Website: https://thehumanapi.comSydney Huang LinkedIn: https://linkedin.com/in/sydney-huangEclipse Website: https://eclipse.xyzWeb3 with Sam Kamani: https://www.linkedin.com/in/samkamani/DisclaimerNothing mentioned in this podcast is investment advice and please do your own research. It would mean a lot if you can leave a review of this podcast on Apple Podcasts or Spotify and share this podcast with a friend. Be a guest on the podcast or contact us - https://www.web3pod.xyz/

As the U.S. and Israeli war with Iran unfolds, one of the most difficult perspectives to hear has been that of ordinary Iranians because of repressive measures inside the country. Among the 4 million outside Iran, there are deep and bitter divisions over the impact of the war. Special correspondent Leila Molana-Allen spoke with Iranians living inside and outside the country. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

The war with Iran has entered its third week, shipping traffic through the critical Strait of Hormuz remains effectively shut off, and the shockwaves to the global supply chain of oil are being felt, with gas prices on the rise. President Trump himself is demanding help from U.S. allies to secure the strait. Nick Schifrin reports. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

On Monday, White House correspondent Liz Landers spoke on the phone with President Trump while he was attending what he described as a "very important meeting" on the Iran war. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

Iran is still blocking the Strait of Hormuz and President Trump is now demanding that NATO allies act to help reopen it. For two views on this and the war, Amna Nawaz spoke with retired Vice Admiral Kevin Donegan and Nathalie Tocci. Donegan is the former commander of the U.S. 5th Fleet and is now at the Middle East Institute. Tocci is Professor of Practice at Johns Hopkins SAIS Europe. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

Christian; Follower of GOD Servant of CHRIST        Combat Veteran; U.S. Marine Corps Urban Warfare Instructor;       S.R.T. Commander Active Shooter Response Team Law Enforcement Los Angeles Police (L.A.P.D.) Police Officer / Fugitive RecoveryF.B.I. Instructor N.R.A Instructor Competition Shooter; Multi Time State Rifle Pistol Champion Hunting; Life Long Hunter Proffessional Hunter and Guide Private Security Contractor; Several Agencies,  Current.Patreon https://bit.ly/3jcLDuZthe LORD is a Man or War, Exodus 15 

This year's MWC took place as the telecom industry is at a crossroads, with additional monetization of 5G beyond mobile broadband less certain, smartphone growth flattening, AI influence increasing, and more questions than answers about the future. In this episode, Neil Shah of Counterpoint Research, Leonard Lee of Next Curve, and I discuss our experience at the event, and analyze the traction and monetization of 5G Advanced, Autonomous Networks, compare and contrast the progress of Western and Asian markets, the opportunity for AI for telecom, early use cases, and the prospect of RAN for AI. 6G and more. We also delve into whether telcos are better positioned for the sovereign AI and Data Center market. Index: 00:00 - Intro 00:35 - Guest intro (Neil Shah, Leonard Lee) 01:10 - MWC attendance 02:23 - Major themes of the event - 5G Advanced, AI, Autonomous Networks, 6G 07:00 - AI Ops for operators (AI for Telco) - Customer Care, Marketing, Billing, HR, Network Management, etc. 14:43 - AI for Networks Ops - Challenges,(data for AI) opportunities, and progress so far 17:38 - Autonomous Networks - Chinese operators at Level-4 (pockets), others at Level-2/2.5 21:30 - Current status of AI - Frank talk by Samsung Network executives on the current status 23:14 - Challenges of extending Autonomous Networks beyond China (by Chinese vendors), need for monetization opportunities 25:56 - Can the 5G Advanced monetization use case, successful in China, work in the US/Europe? 29:42 - RAN for AI, feasibility of GPU at Base stations, and challenges (power, weight, space) 33:29 - 6G - Qualcomm sensing demos, Ericsson/Apple - 5G/6G spectrum sharing (MRS) demo, uplink, need for monetization going beyond wireless service 41:25 - Are operators better positioned to offer Sovereign AI Data Centers - Deutsche Telekom's strategy, similar approach by Middle East /Korea, Is sovereignty is about data or also includes models?  50:50 - Did MWC 2026 move the needle for operators? 52:35 - Closing

From August 30, 2024: Elliot Jones, a Senior Researcher at the Ada Lovelace Institute, joins Kevin Frazier, Assistant Professor at St. Thomas University College of Law and a Tarbell Fellow at Lawfare, to discuss a report he co-authored on the current state of efforts to test AI systems. The pair break down why evaluations, audits, and related assessments have become a key part of AI regulation. They also analyze why it may take some time for those assessments to be as robust as hoped. To receive ad-free podcasts, become a Lawfare Material Supporter at www.patreon.com/lawfare. You can also support Lawfare by making a one-time donation at https://givebutter.com/lawfare-institute.Support this show http://supporter.acast.com/lawfare. Hosted on Acast. See acast.com/privacy for more information.

Andrew Pollard speaks with TNA Knockout Dani Luna:00:41 - Challenging for the Knockouts Title at TNA Sacrifice01:17 - Missing TNA Genesis due to visa issues02:24 - Brutal dog collar match with Indi Hartwell03:26 - Incorporating the chain into her presentation03:51 - Pressure and privilege of the Knockouts division05:47 - Current stacked Knockouts line-up07:12 - Thoughts on non-TNA talent holding TNA gold08:42 - Wider WWE and TNA relationship09:57 - Potential WWE opponents11:19 - Signing with WWE at 2012:59 - Dealing with crazy international schedule14:19 - Rayne Leverkusen signing with WWE15:42 - Backstage vibe after TNA-AMC move17:26 - Hopes for the rest of 2026ENJOY!Follow us on Twitter:@CulturedLeftPeg@WhatCultureWWE Hosted on Acast. See acast.com/privacy for more information.

Cattle futures wobbled Friday with uneven outside markets and wonderment about the potential strike at the JBS plant in Greeley next week. Live Cattle futures closed an average of 42¢ lower. Feeder Cattle futures were mixed, from an average of 64¢ lower to an average of 68¢ higher. Week to week on Friday, Live [...]

The gang is back and there's plenty to unpack. Sleazy, Mr. PBS, and Robzilla kick things off by catching up on the past few weeks and diving into the escalating war in Iran, breaking down the major developments and discussing what the potential global implications could be moving forward.Shifting gears to the entertainment world, the hosts tackle the massive Paramount and Warner Bros. merger. What could it mean for Hollywood labor, the future of streaming, and the consumers stuck in the middle of another corporate mega-deal? The crew shares their thoughts on the industry shakeup.Next up, Robzilla returns with another installment of the fan-favorite segment Zilla's Tubi Pick, highlighting a hidden gem lurking in the glorious depths of Tubi's streaming jungle.Then Robzilla and Sleazy dive into a full spoiler discussion of the FX hit series The Beauty – Season 1, breaking down the story, performances, and whether the show lives up to the hype.To close things out, the crew fires up another classic segment, “Whatchu Watchin',” where everyone shares the movies and shows currently lighting up their screens.Current events, industry shakeups, streaming recommendations, and TV deep dives… it's all packed into Episode 228 of The Sleazy Podcast.

Current events in the Middle East are already having a knock on effect for many at home as fuel costs rise - potentially impacting members of the hobby who are already operating on a tight budget. In this episode Chris discusses ways to help reduce the costs associated with World War Two reenacting..... As ever, a very big thank you to everyone that supports the Podcast via  Patreon - we really couldn't do this without you ! Why not sign up and become one of our growing band of supporters with access to all of our Patreon exclusive content and more for as little as $5 a month.  www.patreon.com/reenactorpodcast    

Wildfires are also out of control in South Dakota and Kansas at this time.

In this episode, we dive into one of the most controversial and disturbing comics ever published — Crossed by Garth Ennis and Jacen Burrows.Originally released in 2008, Crossed presents a brutal vision of societal collapse where a mysterious contagion strips humanity of all restraint, turning the infected into sadistic killers marked by the red cross across their faces.This episode explores the entire first volume (Issues 0–9), breaking down the story arc, the major characters, and the themes that make the series both fascinating and deeply unsettling.We follow Stan, Cindy, and a small group of survivors as they attempt to navigate a world where civilization has collapsed almost overnight. Along the way we examine the evolution of the Crossed themselves, the psychological toll on survivors, and the moral compromises that arise when survival becomes the only priority.We also explore how Crossed reflects real-world anxieties, including themes of societal fragility and disaster response — ideas that Garth Ennis has cited as inspiration following events like Hurricane Katrina.Content warning: This series contains extreme violence and disturbing subject matter. Listener discretion is advised.If you're a fan of horror comics or want to understand why Crossed remains one of the most talked-about graphic novels in modern horror, this episode provides a full breakdown of the first run of the series.Send us a message (I'm not able to reply)Support the showPage Chewing Blog Page Chewing Forum Film Chewing PodcastSpeculative Speculations Podcast Support the podcast via PayPal Support the show by using our Amazon Affiliate linkJoin Riverside.fm Co-Hosts: Jarrod Varsha Chris Jose Carl D. Albert (author) Thomas J. Devens (author) Alex French (author) Intro and Outro Music by Michael R. Fletcher (2024-Current)

In this episode of Page Burners, the crew continues their journey through Midnight Tides, Book Five of Malazan Book of the Fallen by Steven Erikson, diving deep into the chaos and revelations of the late-book chapters as the Letherii–Edur conflict erupts into full war.The discussion explores the sudden devastation unleashed by Letherii sorcery, wiping out entire villages and throwing the Edur world into upheaval. The hosts unpack the emotional weight of Buruk's tragic storyline and Seren Pedac's complicated reaction to his death, debating whether Erikson's “fog of war” storytelling heightens the tension or obscures the emotional impact.From there, the conversation branches into some of the book's biggest mysteries. What is the Empty Hold, and why might Seren Pedac be tied to its power? Who are the mysterious “Mistresses,” and how does the awakening of Death in Lether connect to the shifting metaphysical balance of the world?The crew also examines the arrival of the Crimson Guard and the enigmatic Iron Bars, whose appearance raises new questions about Lether's place in the broader Malazan world.Meanwhile, the discussion turns toward Trull Sengar and the Edur war campaign, touching on the strange presence of the Jheck, the implications of a Tiste Edur with Andii traits, and the broader question of how disconnected the Edur may have become from their own origins.Finally, the hosts dive into one of the novel's most bizarre and fascinating threads: Udinaas' journey into a strange pocket realm inhabited by ghostly T'lan Imass, the shocking revelation of his son's existence, and the tangled manipulations of the dragon-blooded powers moving behind the scenes.As always, theories fly, timelines get debated, and the group wrestles with the sprawling mythology that makes Malazan one of fantasy's most ambitious series.Send us a message (I'm not able to reply)Support the showPage Chewing Blog Page Chewing Forum Film Chewing PodcastSpeculative Speculations Podcast Support the podcast via PayPal Support the show by using our Amazon Affiliate linkJoin Riverside.fm Co-Hosts: Jarrod Varsha Chris Jose Carl D. Albert (author) Thomas J. Devens (author) Alex French (author) Intro and Outro Music by Michael R. Fletcher (2024-Current)

We're back with The Smart Stepmom, Laura Petherbridge! We continue our discussion about stepfamily life by picking up where we left off in part 1.Specifically, Laura and I discuss the following: Current trends with stepfamilies.For example, the term “bonus mom” is now commonly used instead of “stepmother.” Is this helpful or hurtful?Custody changes—moving from mothers having full custody to 50/50 arrangements.Why children tend to have a harder time connecting with stepmothers as opposed to stepfathers.The many stepfamilies in the Bible and how Laura believes God views stepfamilies.Whether you're personally part of a stepfamily or not, you'll be blessed by Laura's warmth, wit, and wisdom. Please join us! Laura Petherbridge, The Smart StepmomWebsite: https://www.thesmartstepmom.com/Dr. Karin & Pastor Elliott AndersonWebsite: http://loveandlifemedia.com/Empowered Dating Playbook: smarturl.it/EmpoweredDatingBookInstagram: @dr.karin | @pastorelliottanderson

Notre Dame's national championship hopes hinge on at least one explosive wide receiver stepping up from a loaded group, including Micah Gilbert, Cam Williams, Elijah Burris, Quincy Porter, and Mylan Graham. Can any of these dynamic athletes become the reliable playmaker CJ Carr needs in key red zone and third-down moments? Brian Smith analyzes the Irish receiver room's strengths, potential lineup combinations, and the importance of route running, hands, and consistency at the Power Four level. Key topics include whether Notre Dame will employ more four-wide-out sets, how red zone threats like Porter and Graham can shift the offense, and which new faces might surprise this season. With a deep, athletic roster, will refined chemistry and leadership be the missing ingredient for Notre Dame to capture the 2026 national title? Everydayer Club If you never miss an episode, it's time to make it official. Join the Locked On Everydayer Club and get ad-free audio, access to our members-only Discord, and more — all built for our most loyal fans. Click here to learn more and join the community: https://theportal.supercast.com/ Support us by supporting our sponsors! 5-Hour ENERGY Have your cake & drink it too. Birthday cake-flavor is back, no fork needed. Vanilla-y cakey flavor, caffeinated kick, and no sugar. It's party time. Order Now at https://5-hourENERGY.com or Amazon. Coast Right now, Coast Pay is offering our listeners up to $2,000 credit when you get started at https://coastpay.com/LOCKEDONCOLLEGE. Term Apply. The Coast Visa®️ Commercial Credit Card is issued by Celtic Bank. All card accounts are subject to credit approval. Mazda Like our players, we're driven by the details. Because highlights make the reel. What it takes to get there makes it count. There's more to a Mazda. Because there's more to you. TurboTax This year you're getting a major upgrade — Intuit TurboTax now has in-person locations nationwide. Visit http://TurboTax.com/local to book your appointment today. Robinhood You're no longer just a spectator. Play by play. You decide. Trade Every Play with Robinhood. Now available across the U.S. Download the Robinhood app now to begin. Futures and cleared swaps trading involves significant risk and is not appropriate for everyone. Event contracts are offered by Robinhood Derivatives, LLC., a registered futures commission merchant and swap firm. Indeed Listeners of this show get a $75 Sponsored Job Credit to help give your job the premium placement it deserves at http://Indeed.com/podcast Gametime Today's episode is brought to you by Gametime. Download the Gametime app, create an account, and use code LOCKEDON for $20 off your first purchase. Terms and conditions apply. FanDuel FanDuel is giving you a way to turn that energy into even bigger potential wins with a College Basketball Parlay Profit Boost. Visit https://FANDUEL.COM to get started — Play Your Game. FANDUEL DISCLAIMER: 21+ in select states. First online real money wager only. Bonus issued as nonwithdrawable free bets that expires in 14 days. Restrictions apply. See terms at sportsbook.fanduel.com. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MD, MI, NJ, PA, IL, VA, WV), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 (WY, KS) or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), 1-877-8-HOPENY or text HOPENY (467369) (NY), TN REDLINE 1-800-889-9789 (TN) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

For people living with kidney disease, clinical trials can offer hope—but not without questions or concerns. Today, we talk with Dr. Nadine Barrett, Glenda Roberts, and Luz Baqueiro about lived experience, community trust, and the power of being asked. In this episode we heard from:  Dr. Nadine J. Barrett is a Professor in the Department of Social Sciences and Health Policy in the Division of Public Health Sciences and the inaugural Senior Associate Dean of Community Engagement and Equity in Research at Wake Forest School of Medicine, she is Associate Director of Community Outreach and Engagement for Wake Forest Comprehensive Cancer Center, the Clinical Translational Science Institute and the Maya Angelou Center for Health Equity. Prior to joining Wake Forest, Dr. Barrett served 13 years in senior leadership roles at Duke University, as the Founding Director of both the Duke Center for Equity in Research and the nationally awarded, Duke Cancer Institute's Office of Health Equity. She is also President of the national Association of Cancer Care Centers, in Washington DC. A medical sociologist by training, Dr. Barrett is a health disparities researcher, expert equity strategist, and a nationally recognized leader in facilitating authentic community, healthcare, and academic partnerships to advance health equity. She develops multi-level interventions to address implicit bias, structural and systemic racism, and inequities that limit access to quality research and trustworthy health care among underserved and marginalized populations. Dr. Barrett brings an equity lens to her work and collaborations to enhance healthcare systems, close the disparities gap in health outcomes, and increase diverse and broad representation in research participation and the research workforce. Glenda Roberts: Prior to joining the Mount Sinai Center for Kidney Disease Innovation as the Director of Communications and Patient Engagement, Glenda V. Roberts was an Information Technology executive with over 35 years of experience with top-caliber corporations, including General Electric, Microsoft and Johnson & Johnson. She was also the Executive Director of the Seattle Transplant House, and the Director of External Relations & Patient Engagement at the University of Washington Center for Dialysis Innovation (CDI) and the Kidney Research Institute (KRI). Before going on dialysis, Glenda managed the progression of her disease for over 40 years using diet and exercise. Since her transplant in 2010, she's completed nine half marathons. Based upon her personal experience with kidney disease, Glenda is a passionate activist for kidney research and patients living with kidney disease. She's involved in myriad patient-centered national and international health care transformation initiatives.  All are focused on addressing patient preferences and improving patient-reported outcomes.   Glenda brings the patient voice to several NIH/NIDDK government and industry research efforts (Kidney Precision Medicine Project, APOLLO), as well as the American Society of Nephrology's Current & Emerging Threats (C-ET) Steering Committee. She's the inaugural co-chair of the Critical Path Institute's Biomarker Data Repository Governance Committee, and a member of the Kidney Health Initiative (KHI) Board of Directors. Additionally, she contributes to the Advisory Boards of LifeCenter Northwest and Home Dialyzors United, and over 15 other industry and academic research advisory committees/boards focused on transplantation, kidney, cardiovascular, and metabolic health. As an ambassador for the National Kidney Foundation, the American Kidney Fund, and the American Association of Kidney Patients, Glenda's advocacy tirelessly advances the voices, needs, and aspirations of the kidney community worldwide. Luz Baqueiro serves as a patient advocate with the National Kidney Foundation (NKF), providing feedback and helping develop new initiatives to better support the Latin American community affected by chronic kidney disease. She also raises awareness of the barriers faced by patients living with renal failure while educating and supporting her community in Georgia. In 2019, Luz was diagnosed with end-stage renal disease (ESRD). With limited resources  in Georgia, she relied on emergency in-hospital dialysis for a year. In August 2021, through self-determination, self-education, and the support of her family and community, she received a kidney transplant.   Additional Resources Clinical Trial Information Hub What is a Clinical Trial? Are Clinical Trials Safe?   Do you have comments, questions, or suggestions? Email us at NKFpodcast@kidney.org. Also, make sure to rate and review us wherever you listen to podcasts.

In episode 169 of The Red Diamond Courier, Bob Chichinske and Doggedbark24 cover the CURRENT content and updates released with update 49 and in the patch notes. This is part 1 of 3, current, DK updates, and future. This update is unique as it is the first of their new cadence and thus some things are not available yet, and we also felt the DK update should get it's own episode, so basically, we wanted to break it down for you all as much as possible! As always, we hope you enjoy, and thanks for listening! Get 15% off Loot Crate & Support our show! Click this link: https://www.anrdoezrs.net/click-100173810-13902093?sid=rdc  and use coupon code - ROBOTSRADIO Try Gamefly for a month for only 10$ and get an extra month free from us! https://www.tkqlhce.com/click-100173810-10495782?sid=rdc Check out https://www.eso-hub.com for all your ESO needs, and download the Dwemer Automaton bot for your discord!  X (Formerly Twitter): Https://www.X.com/RedDiamondCast Come check out Robots Radio and join the Discord: Https://www.robotsradio.net Music Producer Daniel Knisley: https://www.linkedin.com/in/daniel-knisley-20392a194  Help support the show by buying some swag: https://teespring.com/stores/the-red-diamond-courier Learn more about your ad choices. Visit megaphone.fm/adchoices

Listen and subscribe to Money Making Conversations on iHeartRadio, Apple Podcasts, Spotify, www.moneymakingconversations.com/subscribe/ or wherever you listen to podcasts. New Money Making Conversations episodes drop daily. I want to alert you, so you don’t miss out on expert analysis and insider perspectives from my guests who provide tips that can help you uplift the community, improve your financial planning, motivation, or advice on how to be a successful entrepreneur. Keep winning! Two-time Emmy and Three-time NAACP Image Award-winning, television Executive Producer Rushion McDonald interviewed Natalie Southwell. Founder and CEO of The Essence of a Woman, LLC, a female empowerment agency dedicated to helping high‑achieving women rise with confidence, courage, clarity, and faith-driven purpose. The conversation explores: How women can overcome fear, trauma, and misaligned life decisions The role of faith, purpose, and intentionality in decision-making Her frameworks: PAIN and REAL Her personal journey to launching The Essence of a Woman How she guides women across generations—including students, early professionals, mid-career women, and women 50+—toward alignment and leadership.

Listen and subscribe to Money Making Conversations on iHeartRadio, Apple Podcasts, Spotify, www.moneymakingconversations.com/subscribe/ or wherever you listen to podcasts. New Money Making Conversations episodes drop daily. I want to alert you, so you don’t miss out on expert analysis and insider perspectives from my guests who provide tips that can help you uplift the community, improve your financial planning, motivation, or advice on how to be a successful entrepreneur. Keep winning! Two-time Emmy and Three-time NAACP Image Award-winning, television Executive Producer Rushion McDonald interviewed Natalie Southwell. Founder and CEO of The Essence of a Woman, LLC, a female empowerment agency dedicated to helping high‑achieving women rise with confidence, courage, clarity, and faith-driven purpose. The conversation explores: How women can overcome fear, trauma, and misaligned life decisions The role of faith, purpose, and intentionality in decision-making Her frameworks: PAIN and REAL Her personal journey to launching The Essence of a Woman How she guides women across generations—including students, early professionals, mid-career women, and women 50+—toward alignment and leadership.

Stephan Livera and Pieter Wuille discuss Cluster Mempool for Bitcoin Core, its motivations, and its implications for Bitcoin users and miners. Where does the current mempool design have issues? Why is it important to maintain a transparent and reliable open mempool? Pieter Wuille also explains the complexities of transaction clustering and how the new framework improves efficiency and helps keep bitcoin mining open. Timestamps:(00:00) - Intro(01:05) - What is Cluster Mempool?(03:05) - What is its impact on everyday Bitcoin users?(06:21) - How does the mempool work today?(11:52) - Current mempool heuristics and issues(16:37) - Censorship resistance and economic demand(22:56) - Practical implications for exchanges & miners(26:12) - How does cluster mempool work?(29:29) - Transaction clusters & mempool dynamics(37:27) - Should mempools align across the node network?(43:47) - What about other implementations of Bitcoin?(48:17) - Other interesting areas for bitcoin development(52:11) - Closing thoughtsLinks: https://github.com/bitcoin/bitcoin/pull/33629 https://bitcoinmagazine.com/print/the-core-issue-cluster-mempool-problems-are-easier-in-chunks https://delvingbitcoin.org/t/an-overview-of-the-cluster-mempool-proposal/393 https://delvingbitcoin.org/t/mempool-incentive-compatibility/553 Stephan Livera links:Follow me on X: @stephanliveraSubscribe to the podcastSubscribe to Substack

Fresh off a big move from the Washington Spirit to the KC Current, Croix Bethune joins Sam to talk about her feelings on leaving DC and why she's excited to jump into the electric Current.SUBSCRIBE TO THE WOMEN'S GAME NEWSLETTER: https://mibcourage.co/42X5HpBSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

PREVIEW FOR LATER. Rebecca Grant emphasizes the urgent need to accelerate U.S. Navy carrier construction. Despite legal requirements for eleven carriers, current projections suggest a decline, leaving the fleet overstretched against global threats from China. (3)1942 LEXINGTON