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Episode SummaryIn this Think Thursday episode, Molly explores why December feels so emotionally intense and why anticipation plays such a powerful role in our thoughts, feelings, and habits. Anticipation is not just psychological. It is driven by the brain's predictive systems that simulate the future long before it arrives.Using findings from neuroscience, including research highlighted in Neuron, University College London, Stanford University, and studies on dopamine and reward processing, Molly explains how imagining the future changes our emotional state in the present. She shows how anticipation can create craving, heighten anxiety, and influence behavior before anything even happens.Importantly, she connects this science to behavior change. When we understand anticipation, we gain the ability to shape our emotional experience, support our habit goals, and build a stronger relationship with our future selves.What You Will LearnWhy the brain is not reactive but predictiveHow the prospection network simulates possible futuresWhy anticipation activates the same regions involved in memory and emotionHow dopamine spikes during anticipation more than during rewardWhy the holidays intensify emotional forecastingHow the brain treats future you similarly to a strangerHow anticipation contributes to cravings, stress, and anxietyPractical strategies for using anticipation intentionally in behavior changeKey Insights from the EpisodeAnticipation is a physiological experience. Heart rate, dopamine, and emotional readiness all shift based on prediction.December amplifies anticipation because the brain is projecting ahead using vivid emotional memories from past holidays.Many habit patterns with alcohol, eating, and spending are anticipatory rather than reactive in the moment.The medial prefrontal cortex becomes less active when imagining the distant future, which explains why future you feels separate.Mental rehearsal activates the same neural pathways as actual behavior and can support intentional change.Anticipatory framing can influence how stressful events are interpreted afterward.Practical Tools from the Episode1. Anticipate the emotional landscape, not the event. Shift from worrying about what will happen to planning for how you want to feel.2. Rehearse your chosen identity. Imagine yourself acting in alignment with your values to strengthen the neural pathways that support follow-through.3. Shorten the distance to future you. Ask questions like:What will tonight's me thank me forWhat does tomorrow morning's me need4. Anticipate urges with curiosity. Recognize that urges are forecasts of relief, not emergencies.5. Create micro anticipations that ground you. Examples include expecting the first sip of warm tea, a quiet step outside, or the feeling of waking up proud the next morning.Studies and Sources Mentioned2023 review in Neuron on the prospection networkUniversity College London study on dopamine release during anticipatory uncertaintyStanford University research on future self representation in the brainStudies from the University of Michigan and Max Planck Institute on dopamine and anticipation2024 Psychological Science study on anticipatory framing and stress interpretation ★ Support this podcast ★
Trong video này, bạn sẽ học được 2 từ khoá mới. Hãy viết xuống và tiếp tục nghiên cứu thêm nhé.(1) Farmer's carry(2) Neuron vận động
In today's episode, I'm opening the first chapter of what I believe is the most important series I've ever created — a deep dive into progesterone and why it became the heart of my medical practice. For more than 20 years, I've watched this “simple, humble hormone” transform women's lives in ways most conventional medicine overlooks. What started in two small treatment rooms has grown into a 25,000 sq ft facility, and the core of our success comes down to understanding progesterone's impact on the female brain, stress response, and emotional resilience. In this episode, I break down: Why progesterone is far more than a reproductive hormone How it regulates the female stress response (amygdala, hippocampus, prefrontal cortex) Why anxiety, insomnia, irritability, and emotional overwhelm often map directly to progesterone decline Why so many women feel “unraveled” in their 40s — and why it's not their fault The science behind oral vs. sublingual progesterone (and why I use troches) How conventional medicine often misses the root cause The importance of physicians showing their work, their data, and their citations The lived stories and clinical outcomes that changed how I practice medicine If you've ever felt dismissed, unseen, or told that your anxiety or mood changes are “just stress,” this episode is for you. This is the beginning of a 7-part series where I break down the neurobiology, endocrinology, testing, dosing, delivery methods, breast health, perimenopause, and more. Citations: Brinton, Roberta Diaz, et al. “Neurosteroids and Brain Function.” Steroids, vol. 81, 2014, pp. 61–78. Epperson, C. Neill, et al. “New Insights into Perimenopausal Depression: A Neuroendocrine Vulnerability Framework.” The Lancet Psychiatry, vol. 9, no. 2, 2022, pp. 110–118. Frye, Cheryl A. “Neurosteroids—Endogenous Modulators of GABA_A Receptors.” Pharmacology & Therapeutics, vol. 116, no. 1, 2007, pp. 58–76. Genazzani, Andrea R., et al. “Progesterone, Stress, and the Brain.” Human Reproduction Update, vol. 16, no. 6, 2010, pp. 641–655. Meeker, John D., et al. “Environmental Endocrine Disruptors: Their Effects on Human Reproduction and Development.” Reproductive Toxicology, vol. 25, 2008, pp. 1–7. Mellon, Stanley H. “Neurosteroid Regulation of Central Nervous System Development.” Pharmacology & Therapeutics, vol. 116, 2007, pp. 107–124. Mizrahi, Romy, et al. “The Role of Allopregnanolone in Stress, Mood, and Trauma.” Neurobiology of Stress, vol. 11, 2019, 100198. Paul, Steven M., and Graziano Pinna. “Allopregnanolone: From Molecular Pathways to Therapeutic Applications.” Current Opinion in Neurobiology, vol. 48, 2018, pp. 90–96. Pluchino, Nicoletta, et al. “Progesterone and Allopregnanolone: Effects on the Central Nervous System in the Luteal Phase and in Perimenopause.” Gynecological Endocrinology, vol. 36, no. 6, 2020, pp. 441–445. Rasgon, Natalie L., et al. “Perimenopausal Changes in the Brain and Mood: A Review.” Journal of Clinical Endocrinology and Metabolism, vol. 107, no. 4, 2022, pp. 1120–1134. Reddy, Doodipala Samba. “The Neurosteroid Allopregnanolone and GABA-A Receptor Modulation in Epilepsy and Mood Disorders.” Frontiers in Neuroscience, vol. 12, 2018, 933. Schiller, Crystal E., et al. “The Neuroendocrinology of Perimenopausal Depression.” Trends in Neurosciences, vol. 44, no. 2, 2021, pp. 119–135. Schumacher, Michael, et al. “Neuroprotective Effects of Progesterone and Its Metabolites.” Frontiers in Neuroendocrinology, vol. 33, 2012, pp. 415–439. Selye, Hans. “The General Adaptation Syndrome and the Diseases of Adaptation.” Journal of Clinical Endocrinology, vol. 6, no. 2, 1946, pp. 117–230. Sheng, Jun, and György Buzsáki. “Neuronal Firing and Theta Oscillations in the Amygdala During Fear Conditioning.” Neuron, vol. 53, 2007, pp. 653–667. Smith, Sheryl S. “Progesterone Withdrawal Increases Neuronal Excitability in the Hippocampus: A GABA_A Mechanism.” Journal of Neuroscience, vol. 28, 2008, pp. 10171–10179. Snyder, Jonathan S., et al. “Adult Hippocampal Neurogenesis and Stress Regulation.” Nature Reviews Neuroscience, vol. 12, 2011, pp. 1–9. Stanczyk, Frank Z., and Jerilynn C. Prior. “Progesterone and Progestins: A Review of Pharmacology, PK, and Clinical Use.” Steroids, vol. 82, 2014, pp. 1–8. Tu, Ming-Je, et al. “Oral, Vaginal, and Transdermal Progesterone: PK, Metabolism, and Tissue Distribution.” Drug Metabolism Reviews, vol. 52, no. 2, 2020, pp. 1–28. Wang, Jun, et al. “Stress, Amygdala Plasticity, and the Neuroendocrine Interface.” Nature Neuroscience, vol. 10, 2007, pp. 1093–1100. Weinstock, Marta. “The Hippocampus and Chronic Stress.” Neurochemical Research, vol. 42, 2017, pp. 1–12. World Health Organization. Progesterone and Reproductive Function: Clinical Perspectives. WHO, 2019. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.
In this episode, we sit down with Pavan Davuluri, Corporate Vice President of Microsoft's Windows + Devices business, to explore how Windows is evolving into an AI-native platform. Pavan leads the team responsible for strategy, design, and delivery of Windows products across the full stack - from silicon and devices to platform, OS, apps, experiences, security, and cloud. With 23 years at Microsoft, he's driven the creation of the Surface line and now oversees how hardware and software fuse together with AI at the center. We explore how Copilot is being deeply integrated into Windows, the engineering shifts required to make Windows a more proactive and intelligent platform, and how Microsoft balances powerful automation with user control. From Surface design standards influencing the broader ecosystem to supporting OEM partners in the AI PC era, Pavan reveals the principles guiding Windows' transformation and what the computing experience will look like in the next five years.Subscribe to The Neuron newsletter: https://theneuron.aiMicrosoft Surface: https://www.microsoft.com/surfaceWindows AI features: https://www.microsoft.com/windows/ai-features
Ämnet för den här veckan är en artikel i tidskriften Neuron med titeln Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism. Som titeln på artikeln avslöjar så visar författarna till artikeln att det idag inte finns några bra belägg för att tarmfloran påverkar risken för autism eller autismsymptom. Författarna visar det här både genom att visa att det inte finns någon anledning att tro att andelen personer på autismspekrat har förändrats nämnvärt över tid och genom att visa att de studier som påstår sig ha visat en länk har stora metodologiska problem. På Hälsoveckan by Tyngres instagram kan du hitta bilder relaterat till detta och tidigare avsnitt. Hålltider (00:00:00) Introsnack om Alex kärlek till kycklingkorv (00:02:12) Det finns ingen bevisad länk mellan tarmfloran och autism (00:05:05) Andelen människor som har autistiska drag har sannolikt inte ökat över tid (00:13:47) Tre typer av studier som påstås ha visat på en koppling mellan tarmfloran och autism (00:20:31) Djurstudier trots att möss inte har autism (00:23:02) Interventionsstudier på människor med autism
While everyone obsesses over which AI model is smartest, a quiet revolution is happening in the infrastructure layer underneath. Modular just raised $250M at a $1.6B valuation to solve a problem most people don't know exists: AI is locked into expensive, vendor-specific hardware ecosystems. Tim Davis, Co-Founder & President of Modular, joins us to explain why his company is building the "hypervisor for AI"—making it possible to write code once and run it on any GPU, from NVIDIA to AMD to Apple Silicon. We dive into why this matters for businesses, what the Android analogy really means, how companies are seeing 70-80% cost reductions, and whether we're even on the right path to superintelligence.Subscribe to The Neuron newsletter: https://theneuron.aiTry Modular: https://modular.comGetting Started Guide: https://modular.com/get-started
In this episode, we sit down with Scott Guthrie, EVP of Microsoft's Cloud + AI Group, to explore the architecture behind Azure's AI Superfactory. Scott oversees Microsoft's hyperscale cloud computing solutions including Azure, generative AI platforms, and next-generation infrastructure. We dive into Microsoft's strategic approach to AI datacenter buildout, the innovative Fairwater architecture with its 120,000+ fiber miles of AI WAN backbone, and how Microsoft is balancing performance, sustainability, and cost at planet-scale. From dense GPU clusters drawing 140kW per rack to closed-loop liquid cooling systems, Scott reveals the engineering trade-offs behind infrastructure that powers frontier AI models with trillions of parameters. Whether you're an enterprise leader planning AI adoption or a developer curious about cloud architecture, you'll leave understanding how Microsoft is executing on next-gen infrastructure that transforms global challenges into opportunities.Subscribe to The Neuron newsletter: https://theneuron.ai
This week, we are joined by Kevin Mitchell, Associate Professor of Genetics and Neuroscience at Trinity College Dublin, who has committed the unforgivable sin of pointing out that an entire academic and media hype cycle might be built on… well, very little actually. His new co-authored paper in Neuron politely dismantles the highly promoted link between the gut microbiome and autism, which turns out to rest on flawed studies, contradictory findings, creative statistics, and a touching faith in mice burying marbles.Kevin walks us through the joys of observational studies that don't replicate, mouse experiments that don't make sense, and clinical trials where there is no blinding and no control wing, and shockingly, everyone reports feeling better. Meanwhile, journalists and wellness gurus eagerly report each new “breakthrough”, unburdened by any concerns about the strength of evidence or methodological robustness.In the end, the microbiome–autism connection looks less like a sturdy scientific stool and more like three damp twigs taped together by optimism and marketing departments.We finish, naturally, by dragging Matt back out of his panpsychism phase and asking whether consciousness is really fundamental to the universe or just something that happens in podcasters who haven't slept enough.LinksMitchell, K. J., Dahly, D. L., & Bishop, D. V. (2025). Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism. Neuron.Kevin Mitchell's Website
Retool CEO David Hsu reveals that 48% of non-engineers are now shipping software. We explore how AI is democratizing software development, why engineers might stop coding internal apps within 18-24 months, and what this means for the future of work. David shares insights from Retool's survey of 10,000+ companies, Retool's new AppGen program, and how "tomorrow's developers" are using AI to build real production applications on enterprise data.Subscribe to The Neuron newsletter: https://theneuron.aiLearn more about Retool: https://retool.com
Outline00:00 – Intro07:22 – Anatomy of a feedback loop15:12 – A brief historical recap on the history of feedback23:40 – Inventing the negative feedback amplifier34:28 – Feedback in biology, economics, society, and ... board games!52:44 – Negative vs positive feedback59:15 – Feedback, causality, and the arrow of time1:06:22 – Classics: fundamental limitations, uncertainty, robustness1:21:30 – Adaptive control: learning in the loop1:29:50 – Modern AI feedback loops (RL, social media, alignment)1:40:40 – OutroLinksWatt's flyball governor: https://tinyurl.com/ne5nene3Maxwell - "On Governors": https://tinyurl.com/2a7cxj7m Black - "Inventing the negative-feedback amplifier": https://tinyurl.com/yevsemdpNyquist Criterion: https://tinyurl.com/33hfbw8mBode's integral: https://tinyurl.com/53sxkdzuWiener - "Cybernetics": https://tinyurl.com/yta899ayApoptosis: https://tinyurl.com/mcxjycka Predator–prey dynamics (Lotka–Volterra): https://tinyurl.com/5cvx33tn Bird migration cues (photoperiodism): https://tinyurl.com/y2e7t22v Neuron action potentials: https://tinyurl.com/2wemwdn4Economic equilibrium & feedback: https://tinyurl.com/nhdx7r3sEcho chambers: https://tinyurl.com/4v8yk7e8 Game design: https://tinyurl.com/bdhdhv38Gap metric (Vinnicombe): https://tinyurl.com/y9nw3yveGeorgiou, Smith - "Feedback Control and the Arrow of Time": https://tinyurl.com/5xvj76jrAnnaswamy, Fradkov - "A Historical Perspective of Adaptive Control and Learning": https://tinyurl.com/4nfew8vm Algorithmic trading flash crash (2010): https://tinyurl.com/2dsrs8j2AI alignment: https://tinyurl.com/yvs3wnj8Support the showPodcast infoPodcast website: https://www.incontrolpodcast.com/Apple Podcasts: https://tinyurl.com/5n84j85jSpotify: https://tinyurl.com/4rwztj3cRSS: https://tinyurl.com/yc2fcv4yYoutube: https://tinyurl.com/bdbvhsj6Facebook: https://tinyurl.com/3z24yr43Twitter: https://twitter.com/IncontrolPInstagram: https://tinyurl.com/35cu4kr4Acknowledgments and sponsorsThis episode was supported by the National Centre of Competence in Research on «Dependable, ubiquitous automation» and the IFAC Activity fund. The podcast benefits from the help of an incredibly talented and passionate team. Special thanks to L. Seward, E. Cahard, F. Banis, F. Dörfler, J. Lygeros, ETH studio and mirrorlake . Music was composed by A New Element.
„Neuroinformatyka” brzmi jak nauka wyrwana z książek Science Fiction, a jednak zajmują się nią studenci PWr w Kole Naukowym Neuroinformatyki Neuron. W tej rozmowie zarząd kola przybliży nam, co to są Interfejsy Mózg-Komputer, czy granie na komputerze za pomocą myśli jest możliwe, i opowiedzą o Neurohackatonie - imprezie programistycznej która będzie miała miejsce pod koniec listopada na Politechnice Wrocławskiej. Jest to jeden z największych neurohackatonów w Europie!Zaprasza Ewa Śmigaj.
Hi Shiny Mind
Un tema che riguarda milioni di persone e che tocca da vicino la vita quotidiana: l'impatto dell'alimentazione sul cervello e, in particolare, sulla memoria. Il cervello è uno degli organi più sensibili a quello che si mangia, una nuova ricerca condotta dall'Università del North Carolina, pubblicata sulla prestigiosa rivista Neuron, mostra che bastano pochi giorni di una dieta ricca di grassi per alterare il funzionamento della memoria. Il team guidato dalla professoressa Juan Song ha scoperto che una dieta ad alto contenuto di grassi – simile a quella tipica occidentale, ricca di fast food, hamburger e patatine fritte – sovrastimola un gruppo specifico di neuroni nell'ippocampo, la regione del cervello deputata alla memoria.
Behind every AI response, there's an invisible army of humans who trained it. In this episode, we talk with Casper Elliott from Invisible Technologies - the company that's trained 80% of the world's top AI models. We explore how models actually learn, why data quality matters more than quantity, what enterprises get wrong about AI deployment, and whether AI will really automate everyone's jobs. Casper shares insights from working with frontier labs, reveals the surprising skills that make great AI trainers (hint: League of Legends helps), and explains why the future needs more humans, not fewer.Subscribe to The Neuron newsletter: https://theneuron.aiLearn more about Invisible Technologies: https://invisibletech.ai
Computers can see and hear, but they've never been able to smell—until now. In this episode, we sit down with Alex Wiltschko, Founder & CEO of Osmo, to explore how his company is using AI to digitize scent. Alex walks us through how they "teleported" the smell of a fresh plum across their lab, created the world's first AI-designed fragrance molecules, and built Osmo Studio—a platform that lets anyone design custom fragrances in one week instead of two years. We discuss the read/map/write framework for digitizing smell, why scent is tied directly to memory and emotion, and how this technology could eventually detect diseases like cancer and Parkinson's earlier than any current diagnostic. Plus: what does the Museum of Pop Culture smell like, and can AI really create a fragrance from a Bon Iver song?Links: Osmo: https://www.osmo.aiScent Teleportation Update: https://www.osmo.ai/blog/update-scent-teleportation-we-did-itOsmo Studio: https://osmostudios.ai/ Subscribe to The Neuron newsletter: https://theneuron.aiCheck out the sponsor of this video, Flora: https://dub.florafauna.ai/neuronSubscribe to The Neuron newsletter: https://theneuron.aiHosted by: Corey Noles and Grant HarveyGuest: Alex Wiltschko (Founder & CEO, Osmo)Published by: Manique SantosEdited by: Kush Felisilda
Ever wondered who's actually teaching ChatGPT and Claude how to think? Meet Caspar Eliot from Invisible Technologies - the company behind 80% of the world's top AI model training. In this eye-opening conversation, we uncover the massive human workforce behind "artificial" intelligence, why your League of Legends skills might land you an AI job, and the shocking mistakes enterprises make when deploying AI.We discuss:• How AI models really learn (hint: it's not just scraping the internet)• Why data quality beats data quantity every time• The Charlotte Hornets' revolutionary AI scouting system• Whether robots will actually take your job (spoiler: probably not)• The $14.8 billion Scale AI valuation and what it means• Why Mark Andreessen thinks VCs won't be automatedPlus: Caspar reveals the #1 mistake companies make with AI deployment and why "AI-ifying" your current process is doomed to fail.Subscribe to The Neuron newsletter: https://theneuron.aiConnect with Caspar on LinkedIn: https://uk.linkedin.com/in/caspar-eliot-46b9a55aLearn more about Invisible Technologies: https://invisibletech.aiPlease check out the sponsor of this video, Warp.dev: https://warp.dev
From Adobe Max 2025 in Los Angeles, Corey and Grant sit down with Ely Greenfield, Adobe's Chief Technology Officer, to explore the philosophy behind Adobe's practical AI strategy. Discover why the crowd went wild over AI renaming layers, how Adobe thinks about "additive not subtractive" AI, and where creative tools are heading next. Ely shares Adobe's vision for making AI a creative partner that enhances rather than replaces human artistry, and explains why the best AI features are often the most boring ones.Topics covered include: the Photoshop AI Assistant, Harmonize for instant compositing, auto-masking in Premiere Pro, the Express conversational workflow, and Adobe's unique approach to balancing automation with creative control.Read our Adobe Max coverage:• Adobe Reinvents Creative Suite with AI• Day 2 Keynote Recap• NVIDIA's Beyond-GPUs StrategyThis episode was made possible by our sponsor, Clutch: https://clutch.co/resources/how-smbs-see-ai-crawlers?source=theneuron&utm_medium=referral&utm_campaign=newsletter_10-14-2025Related resources:• Adobe Max 2025 announcements: https://www.theneuron.ai/explainer-articles/adobe-goes-all-in-on-ai-max-2025-unleashes-creative-ai-arsenal-across-every-tool• Day 2 Keynote and Sneaks recap: https://www.theneuron.ai/explainer-articles/adobe-max-day-2-the-storyteller-is-still-king-but-ai-is-their-new-superpower• Check out Adobe Firefly: https://firefly.adobe.com/• Project Graph demo: https://www.youtube.com/live/wQza2t9Qs64?t=10409sMake sure to check out Clutch's new report on AI crawling for SMBS! https://clutch.co/resources/how-smbs-see-ai-crawlers?source=theneuron&utm_medium=referral&utm_campaign=newsletter_10-14-2025Subscribe to The Neuron newsletter for daily AI news: https://theneuron.aiOriginal article: https://www.theneuron.ai/explainer-articles/adobe-goes-all-in-on-ai-max-2025-unleashes-creative-ai-arsenal-across-every-tool
Get ready to elevate your Halloween celebrations with the latest episode of the Stress Factor Podcast! Episode 329 features the return of the electrifying DJ B-12, who has curated a 3-hour journey through the pulsating world of drum and bass. With an impressive selection of 100 tracks, this set is a masterclass in mixing that showcases the freshest sounds in the genre. Whether you're a die-hard DnB fan or just looking to add some energy to your Halloween festivities, this episode promises to deliver an unforgettable auditory experience. DJ B-12 has meticulously crafted a blend of uplifting and intelligent drum and bass that will have you dancing in no time. The set features a perfect balance of upfront and vocal styles, ensuring that every listener finds something to connect with. But that's not all, this mix also includes tantalizing hints of the harder, rougher, and darker elements of DnB, making it a versatile soundtrack for any occasion. From the first beat to the last, you'll be captivated by the seamless transitions and expertly layered sounds that only DJ B-12 can deliver. So, whether you're hosting a Halloween party, going for a late-night drive, or simply looking to unwind, tune in to this exhilarating episode and let the music take you away. With DJ B-12 at the helm, you can expect nothing less than a thrilling ride through the depths of drum and bass. Grab your headphones, turn up the volume, and immerse yourself in the vibrant world of DnB this Halloween. Happy listening! This episode contains track and remixes by the following artists and on the following labels: Andy C, Felix Samuel, Armada Music, Electronic Youth, A Sides, ASTIR Recordings, Blossom, UKF, Bloque, KushSessions, Andromedik, Kanine, Grafix, ROVA, Grafix Music, Bzrnt, ElectroBreakz, Aktive, Liquicity Records, Subkey, Fokuz Recordings, Liquefaction, Lizplay Records, ghost., DistroKid, Digital Native, Goldfat Records, Jaydan, Smokin Riddims, Liquefaction, Phrase, Ranger Records, CPH, Phil Tangent, Onward Music, Wood Packa, Monofire Records, NRTK, DNBB Digital, Dr. Uggist, Apothecary Record, Bennie, Born On Road, Divurse, Manifest, SUUNE , inMotion, Sleepless Music Ltd., Monrroe, Must Make Music, Technimatic, Zero T, Hospital Records, Bella Renee, Skellytn, Dim Mak Records, Phloem, Galacy, DLTO, onesevenfour, Pola and Bryson, Shogun Audio, Flava D, Lauren Archer, Frameshift, Axel Boy, B.O.M, DnB Active Records, Wood Packa, Monofire Records, 1991, I99I, Henry, Nostre, Celsius Recordings, Twintone, Offworld Recordings, Wresker, Offworld Recordings, Sustance, Catching Cairo, Gravity, Totally Liquid, Lexurus, DIEDE, Krakota, Lee Mvtthews, NU, Elevate Records, Ryan Audley, Elephant Trunk, Skyfade, YANA Music, Solid State, Joy Doc, High Tea Music, Clank, Maider, CandM Records, Clusion, Precinct, Ragdoll, Yumi Recordings, Children Of Our Stars, IAMDOOMED, Blu Saphir, Culture Shock, Sarah De Warren, Culture Shock Music, Overview Music, Sub Focus, Fireboy DML, Irah, Positiva, DIMOD, BazAan, S9, I.C.U, Lateral, MYKOOL, YANA Music, T Phonic, Sense, Roadblock Records, Casa, CASA Sounds, Metrik, DK Foyer, Liquid Brilliants, Bad 4 Life, Bevent, Matrix and Futurebound, Miss Trouble, Metro, Viper Recordings, Freaks and Geeks, Blooom, Cameron Hayes, YASUKI, Mad Joker, GOVERNADE, KEYS MUSIC, Twintone, Lucidity, FX909 MUSIC, Frameshift, Subsonic, Sasha Busko, Spring Tube AC, Sigma, Julia Church, Another Rhythm, Text, Outhouse Sounds, London Elektricity, Danny Byrd, Fast Soul Music, Sacha, Day Ones, T and Sugah, A Little Sound, Basstripper, Shaki, DA TU, AEON MODE, ANY, KushSessions, Syglit, Modern Conveniences, Airstrike, Sodie, Guy Arthur, MORE BASS MORE GOOD, Tim Clay, Function Records, Carbon Music, S.P.Y, DARKMTTR Records, Freaks and Geeks, Nu La, Playa, Influenza Media, nCamargo, NCounter Music, Lemon D. Infrared Records, Dan Guidance, Neuron, Fokuz Recordings, Yumi Recordings, Mia Kirkland and Danny Byrd, B1 Recordings Tracklist 01. Andy C - Ricochet feat. Felix Samuel (Extended Mix) [Armada Music] 02. Electronic Youth - In Your Eyes (A Sides Mix) [ASTIR Recordings] 03. Blossom - Stronger [UKF] 04. Bloque - Smoke [KushSessions] 05. Andromedik and Kanine - Ascension [Andromedik] 06. Grafix and ROVA - Let Me Down [Grafix Music] 07. Bzrnt - Wake Up [ElectroBreakz] 08. Aktive - On My Own [Liquicity Records] 09. Subkey - Stellar [Fokuz Recordings] 10. Liquefaction - Summer Time [Lizplay Records] 11. ghost. - I SEE COLORS (Extended Mix) [DistroKid] 12. Digital Native - Journey Through [Goldfat Records] 13. Jaydan - Devotion [Smokin Riddims] 14. Liquefaction - Move To You [Lizplay Records] 15. Phrase - Get To Know [Ranger Records] 16. CPH and Phil Tangent - Can You Hear Me [Onward Music] 17. Wood Packa - Give It a Moment [Monofire Records] 18. NRTK - Drifted Days [DNBB Digital] 19. Dr. Uggist - Remedy [Apothecary Records LLC] 20. Bennie - Drag Me Down [Born On Road] 21. Liquefaction - Motion [Lizplay Records] 22. Divurse - Coming Back [Manifest] 23. SUUNE and inMotion - Heartless (Extended Mix) [Sleepless Music Ltd.] 24. Monrroe - Cold Shoulder Therapy [Must Make Music] 25. Technimatic - The Golden Section (Zero T Remix) [Hospital Records] 26. Bella Renee and Skellytn - Mirage [Dim Mak Records] 27. Phloem - Cathartic [Galacy] 28. DLTO - All Night [onesevenfour] 29. Pola and Bryson - Aurora [Shogun Audio] 30. Flava D and Lauren Archer - The Cycle [Hospital Records] 31. Frameshift - Deep Space [Lizplay Records] 32. Axel Boy and B.O.M - Over You [DnB Active Records] 33. Wood Packa - Meta Heart [Monofire Records] 34. 1991 - Get A Good Feeling (Extended Mix) [I99I] 35. Henry and Nostre - Moonlight [Celsius Recordings] 36. Twintone - Last Minutes On Earth [Offworld Recordings] 37. Grafix - Night Drive [Grafix Music] 38. Wresker - The Special One [Offworld Recordings] 39. Sustance Ft. Catching Cairo - I Want You [Shogun Audio] 40. Gravity - Escalation [Totally Liquid] 41. Lexurus - Live The Lie (ft. DIEDE) [Liquicity Records] 42. Krakota - Breathe In [Sleepless Music Ltd.] 43. Lee Mvtthews and NU - Made For You [Elevate Records] 44. Ryan Audley - CYHMN [Elephant Trunk] 45. Skyfade - Aries [YANA Music] 46. Solid State and Joy Doc - Let You Go [High Tea Music] 47. Clank and Maider - Stay with Me [CandM Records] 48. Clusion - Heat Haze [Precinct] 49. Andromedik - Calling (ft. Ragdoll) [UKF] 50. Frameshift and Twintone - A Poison In Disguise [Yumi Recordings] 51. Children Of Our Stars - Nostalgia (IAMDOOMED Remix) [Blu Saphir] 52. Culture Shock and Sarah De Warren - All The Things She Said (Culture Shock Version) [Culture Shock Music] 53. Monrroe - Apostate [Overview Music] 54. Sub Focus, Fireboy DML and Irah - Original Don (Extended Mix) [Positiva] 55. DIMOD and BazAan - Stratus [Offworld Recordings] 56. S9 and I.C.U - Faster [Liquicity Records] 57. MYKOOL and Lateral - Stay [YANA Music] 58. T-Phonic and Sense - What's The Rush [Roadblock Records] 59. Casa - Giving Me Light [CASA Sounds] 60. Metrik - Setting Sun [Hospital Records] 61. DK Foyer - Higher [Liquid Brilliants] 62. Liquefaction - Station [Lizplay Records] 63. Bad 4 Life - Ressurection (Bevent Remix) [Liquid Brilliants] 64. Matrix and Futurebound - Motivation (ft. Miss Trouble) [Metro Viper Recordings] 65. Freaks and Geeks and Blooom - Bitter End ft. Cameron Hayes [Shogun Audio] 66. YASUKI - Think Of You [Manifest] 67. Mad Joker and GOVERNADE - LIVE FIVE STORE [KEYS MUSIC] 68. Twintone and Lucidity - Feels Unspoken [FX909 MUSIC] 69. Subsonic - Underwater [UKF] 70. Twintone and Lucidity - Save Me [FX909 MUSIC] 71. Sasha Busko - Charged Morning [Spring Tube AC] 72. Sigma - MAGNETIC ft. Julia Church (Extended Mix) [Another Rhythm] 73. Text - Nothing Else Matters When I'm With You [Outhouse Sounds] 74. London Elektricity and Danny Byrd - Echoes In The Dance [Fast Soul Music] 75. Sigma - ONLY YOU ft. Sacha [Day Ones] 76. Twintone - Felt [Offworld Recordings] 77. T and Sugah - Ayaya [UKF] 78. Andromedik, A Little Sound, and Basstripper - Sunlight (Extended Mix) [Andromedik] 79. Shaki and DA TU - Silver and Gold [Offworld Recordings] 80. AEON MODE - Fireflies (ft. ANY) [UKF] 81. Liquefaction - Call My Name [KushSessions] 82. Syglit - Roll The Dice [Modern Conveniences] 83. Airstrike and Sodie - Last Words [Offworld Recordings] 84. Monrroe - Romance [Overview Music] 85. Guy Arthur - STAY WITH ME [MORE BASS MORE GOOD] 86. Gravity - Body And Soul [Totally Liquid] 87. Tim Clay - Future Nostalgia [Function Records] 88. Zero T - Holding On [Carbon Music] 89. Liquefaction - Void (Accelerated Remix) [Lizplay Records] 90. S.P.Y - Void [DARKMTTR Records] 91. Frameshift - Into Darkness [Lizplay Records] 92. Freaks and Geeks and Nu-La - Space and Time [Elevate Records] 93. Playa - Lessons Learned [Influenza Media] 94. Grafix - Into Your Arms [Grafix Music] 95. nCamargo - Soul Echoes [NCounter Music] 96. Lemon D - High Tech Souls [Infrared Records] 97. Dan Guidance and Neuron - Neural Circuit [Fokuz Recordings] 98. Frameshift and Twintone - Another Place (Original Mix) [Yumi Recordings] 99. Grafix - Telling Me (Original Mix) [Grafix Music] 100. Mia Kirkland and Danny Byrd - Lonestar (Extended) [B1 Recordings]
AI is changing what we need from our computers—but does that mean you need an "AI PC"? Corey and Grant sit down with Logan Lawler from Dell Technologies who leads Dell Pro Max AI solutions to decode what matters (and what doesn't) when buying or upgrading your next computer. From CPUs and GPUs to memory, NPUs, and traps to avoid, this episode is your practical roadmap for staying future-ready through the next five years of AI-powered work.Dell Pro Max Workstations: https://www.dell.com/en-us/plcp/lp/dell-pro-max-pcs LM Studio LIVE tutorial: https://www.youtube.com/watch?v=Ai3sBeBdA1Y Kiwix Wikipedia Download: https://en.wikipedia.org/wiki/Kiwix One Trainer: https://github.com/Nerogar/OneTrainerJawset Postshot: https://www.jawset.com/Subscribe to The Neuron newsletter: https://theneuron.aiCheck out the Reshaping Workflows Podcast: https://reshaping-workflows.simplecast.com/
This week, Paul and Alec discuss a number of small Yu-Gi-Oh updates like the Neuron event, Holiday Charity, and the Fallen and the Virtuous Deck release. MTG also has a new tournament series with a huge $500,000 prize pool, and both Xbox and PlayStation have thoughts on their next gen consoles!
AI is changing what we need from our computers—but does that mean you need an "AI PC"? Corey and Grant sit down with Logan Lawler from Dell Technologies who leads Dell Pro Max AI solutions to decode what matters (and what doesn't) when buying or upgrading your next computer. From CPUs and GPUs to memory, NPUs, and traps to avoid, this episode is your practical roadmap for staying future-ready through the next five years of AI-powered work.Dell Pro Max Workstations: https://www.dell.com/en-us/plcp/lp/dell-pro-max-pcs LM Studio LIVE tutorial: https://www.youtube.com/watch?v=Ai3sBeBdA1Y Kiwix Wikipedia Download: https://en.wikipedia.org/wiki/KiwixOne Trainer: https://github.com/Nerogar/OneTrainerJawset Postshot: https://www.jawset.com/Subscribe to The Neuron newsletter: https://theneuron.aiCheck out the Reshaping Workflows Podcast: https://reshaping-workflows.simplecast.com/
Wenn wir uns vorstellen, was andere Menschen empfinden, um angemessen auf sie zu reagieren, sind wir empathisch. Das kann anstrengend sein, stärkt aber unsere sozialen Bindungen. Diane Hielscher und Main Huong Nguyen sprechen über die Facetten von Empathie.**********An dieser Stelle findet ihr die Übung:00:33:46 - Geleitete Meditation zum Thema Empathie**********Quellen aus der Folge:Fredrickson, B. L., Cohn, M. A., Coffey, K. A., Pek, J., & Finkel, S. M. (2008). Open hearts build lives: positive emotions, induced through loving-kindness meditation, build consequential personal resources. Journal of personality and social psychology, 95(5), 1045. Hein, G., Silani, G., Preuschoff, K., Batson, C. D., & Singer, T. (2010). Neural responses to ingroup and outgroup members' suffering predict individual differences in costly helping. Neuron, 68(1), 149-160. Muradova, L. (2025). Empathy and Political Reasoning: How Empathy Promotes Reflection and Strengthens Democracy. Cambridge University Press. Singer, T., & Klimecki, O. M. (2014). Empathy and compassion. Current biology, 24(18), R875-R878. Roth, M., Schönefeld, V., & Altmann, T. (2016). Trainings-und Interventionsprogramme zur Förderung von Empathie. Springer Berlin Heidelberg. **********Mehr zum Thema bei Deutschlandfunk Nova:Manipulation: Achtsam bei uns bleibenNarzissmus: Wie wir mit selbstbezogenen Menschen umgehenEmpathie und Selbstschutz: Wie wir achtsam mit Menschen umgehen können, die sich negativ verhalten**********Den Artikel zum Stück findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .**********Ihr habt Anregungen, Ideen, Themenwünsche? Dann schreibt uns gern unter achtsam@deutschlandfunknova.de
Learn how to use NVIDIA's Nemotron open-source AI models with VP Kari Briski. We cover what Nemotron is, minimum hardware specs, the difference between Nano/Super/Ultra tiers, when to choose local vs cloud AI, and practical deployment patterns for businesses. Perfect for anyone wanting to run powerful AI locally with full control and privacy.Resources mentioned:NVIDIA Nemotron Models: https://www.nvidia.com/en-us/ai-data-science/foundation-models/nemotron/Start prototyping for free: https://build.nvidia.com/explore/discoverSubscribe to The Neuron newsletter: https://theneuron.aiWatch more AI interviews: https://www.youtube.com/@TheNeuronAI
AI search is fundamentally changing how people find information online, but it's also creating a Wild West of spam, manipulation, and brand impersonation. SEO expert Mark Williams-Cook joins us to discuss why he calls AI a "leaky bucket," how expired domains are gaming LLMs, and what the death of the link graph means for the future of search. We'll explore practical strategies for making your site visible to AI, the risks brands face from AI phishing, and whether SEO is truly dead or just evolving. Perfect for anyone who owns a website or runs a business.Subscribe to The Neuron newsletter: https://theneuron.aiGuest: Mark Williams-Cook - Director at Candour, Founder of AlsoAskedFind Mark on LinkedIn: https://www.linkedin.com/in/markseo Search with Candour podcast: https://withcandour.co.uk/podcast
理研CBSの長井淳さん(@JunNagaiLab)ゲスト回(前編)。どうしてグリア研究に至ったか。大学院時代の”思い出”、再現性問題、バル・カークとのポスドク生活など (9/19 収録)Show Notes (番組HP):理研CBSグリア-神経回路動態研究チーム (長井ラボ)やたらうまいてんぷらを食べる我々柳下さんまこっちゃん (長井と早稲田大学生命医科学科の同級生) 過去NR登場回:1,2,3音楽で溢れる家庭で盲目のピアニスト辻井伸行さん 安田涼平さん 過去NR登場回誤:慶應医学部の先生が引退して 正:慶應医学部卒の早稲田大学名誉教授竜田邦明先生が理工学研究科長(当時)として(長井)TWIns大島登志男先生御子柴克彦先生花嶋先生坂内さん早稲田って人をバカにさせる大学 例2コ上の先輩と会社やってるCdk5とReelinシグナリングの仕事Tom CarmichaelDC1の締切に向けてcultureの系に切り替えてまとめた仕事Bal Khakh役人から見ていろんな研究やってるなっていう (そうなっているのだろうか…) (長井)Michael Sofroniewアストロ”スカー”/ボーダーの見方を大きく変えたNature2016論文InscopixInscopix miniaturized scopeの元になった原著(Ghosh2011 Nat.Methods) 原価1-10USDでした(萩)UCLA miniscopeEppendorfのmicroloader 個人的には火でシリンジ引いたことはないです(萩)お世話になった元同僚 Xinzhu Yu (現UT Houston)の”CalEx” 2018Neuron論文Yi ZuoNIH Directors Pioneer Award (DP1)CEPsh glia 線虫のアストロサイト様細胞 参考: worm, fly, fish, mouse, humanのアストロサイトアストロサイトはextracellular compartmentalizationECM: ExtraCellular Matrix 水分子チャネル アクアポリングルタミン酸トランスポーターGLT1 on 神経 GLT1がシナプスの周りにあるCHDI FoundationアストロのAldh1l1-CreERT2ライン等を作った論文(2016年Neuron)2019年の線状体アストロサイトに関するCell論文GABAB受容体とGIRKアストロのRNA-seqデータベースKCNQがD1の下流で動くGq primingでGi-mediated カルシウムATPアストロをprimingしておくとGABAでCaが上がるアストロ反応がgateされる最近のScience論文GfaABC1Dプロモータ by Michael BrennermicroRNA targeting sequenceでアストロ特異性を担保したCre AAVスロンボスポンジンはシナプトジェネシスシグナルBen BarresNicola AllenによるPreviewNature 2018でHailan Huが参考にした Nature Neuro 2014 by Khakh labHailan HuによるNature News&ViewsMasmanidis発生期にD1/D2特異的アストロサイトが存在する(かも)、でも成体期では形態的特異性なし(Fig. 5)。Michael FanselowJosh JohansenAndrew HolmesラジバンダリOlena BukaloHolmesのtouchscreenプロトコル論文Maiken NedergaardHajime HiraseがYusteのところでCaとった (実験自体はむしろブザキ研時代?) でしたね。すみません(長井)iβARKOptoXR by DeisserothEme KatoさんMelanopsinParapinopsinOPN3 の応用tool by Oferchicken OPN5 GPCR系Opsinは共役しているG-proteinが生物種や細胞によって異なるらしく複雑ですね(長井)RCaMP3 by 坂本さんSERCA inhibitor (CPA)でアストロCaが上がる (Fig. 4D-E)Editorial Notes:自分で基準と期間(締切意識)を設けるようになったのは、早稲田でお祭りモードが長かった反省からかも(長井)Upでバーンは嫌だな...昔ガラスでひどく手を切ったことがあるので(萩)院時代アストロ研究を横目で見ていましたが、当時からすると、自由行動下vivoイメージングの技術が進んで生理的条件での機能の理解が進んでますね(神経にも当てはまるが、アストロでは電気生理的手法が使えないので、よりジャンプが大きい印象)。血管との関連ももっと解像度高くなりそう(脇)
TWiN explains how visual neurons show functional flexibility by selectively responding to subsets of inputs representing attended objects while ignoring those conveying information about irrelevant objects. Hosts: Vincent Racaniello, Vivianne Morrison, and Tim Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Gamma-band synchronization in visual cortex (Nat Comm) Timestamps by Jolene Ramsey. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv
Everyone's talking about the AI datacenter boom right now. Billion dollar deals here, hundred billion dollar deals there. Well, why do data centers matter? It turns out, AI inference (actually calling the AI and running it) is the hidden bottleneck slowing down every AI application you use (and new stuff yet to be released). In this episode, Kwasi Ankomah from SambaNova Systems explains why running AI models efficiently matters more than you think, how their revolutionary chip architecture delivers 700+ tokens per second, and why AI agents are about to make this problem 10x worse.
In this episode, we're joined by Ahmed El-Kishky, research lead at OpenAI, to discuss their historic victory at the International Collegiate Programming Contest (ICPC) where their AI system solved all 12 problems, beating every human team in the world finals. We dive into how they combined GPT-5 with experimental reasoning models, the dramatic last-minute solve, and what this means for the future of programming and AI-assisted science. Ahmed shares behind-the-scenes stories from Azerbaijan, explains how AI learns to test its own code, and discusses OpenAI's path from this win to automating scientific discovery over months and years.Subscribe to The Neuron: https://theneuron.aiWisprFlow: https://wisprflow.ai/neuronOpenAI: https://openai.com
Microsoft AI CEO Mustafa Suleyman (co-founder of DeepMind) joins The Neuron to discuss his provocative essay on "Seemingly Conscious AI" and why machines that mimic consciousness pose unprecedented risks - even when they're not actually alive. We explore how 700 million people are already using AI as life coaches, Microsoft's massive $208B revenue strategy for AI, and exclusive features like Copilot Vision that can see everything you see in real-time.Key topics:• Why AI consciousness is an illusion - and why that's dangerous • Microsoft's 2 gigawatt datacenter expansion (2.5x Seattle's power usage)• MAI-1 Preview breaking into the top 10 models globally• The future of AI browsers and autonomous agents• Why granting AI rights could threaten humanitySubscribe to The Neuron newsletter (580,000+ readers): https://theneuron.aiResources mentioned:• Mustafa's essay "Seemingly Conscious AI Is Coming" https://mustafa-suleyman.ai/seemingly...• Try Copilot Vision: https://copilot.microsoft.com• Microsoft Edge AI features: https://www.microsoft.com/en-us/edge• MAI-1 Preview models: https://microsoft.ai/news/two-new-in-...Special thanks to today's sponsor, Wispr Flow: https://wisprflow.ai/neuron
X2M.159 – Quaquaversal | Starfield Astrocyte Quaquaversal (Latin quaqua “whichever way” + versus “turned”) signifies spreading in all directions, unlike a line locked into one axis.¹ In geology it describes strata dipping outward from a central point; in PH12 it names consciousness opening in every direction at once. • Philosophical resonance: Paradise Lost narrowed perception into single channels of shame and toil. Quaquaversal reopens perception as manifold, unconfined by decay. • Cosmic image: The Starchild's mind is refracted like starlight, not bound to one trajectory but diffusing across dimensions. • Theological anchor: Ezekiel's vision of the wheels “full of eyes all around” (Ezek. 1:18) parallels the quaquaversal spread — perception that sees every direction at once.² • Neurobiological analogy: Just as neurogenesis remaps hippocampal circuits (see X2M.164), so quaquaversal spreading allows new outputs from old inputs, perception re-coded for multidirectionality.³ In PH12's runtime, Quaquaversal inaugurates the Starfield Astrocyte: consciousness no longer a tunnel but a radiating starfield. It is the first spark of transfiguration — spreading outward, carrying glory into every vector. ⸻ Footnotes ¹ Oxford English Dictionary, “Quaquaversal,” s.v. ² Ezekiel 1:18. ³ Sailor et al., “Synaptic Remodeling in Dentate Granule Cells,” Neuron (2017). ⸻ Glorification | The Final Frontier Going Boldly Where The Last Man has Gone Before! Decrease time over target: PayPal or Venmo @clastronaut Cash App $clastronaut
In our wonderful interview, Dr. Danna Trachtenberg Zeiger and I celebrate her debut picture book, Rewriting the Rules, a STEM nonfiction picture book which was just released from Millbrook Press (Carol Hinz, editor) on September 9, 2025". She is represented by Gaby Cabezut at The Seymour Agency. A published scientist, Danna's research has appeared in top scientific journals such as Science, Neuron, and PNAS. Formerly a biology professor and program director at Fisher College, she now focuses on writing for children. In our conversation Danna describes her transition from scientist to author, and the benefits that a career in science can bring to the writer's table. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
In our wonderful interview, Dr. Danna Trachtenberg Zeiger and I celebrate her debut picture book, Rewriting the Rules, a STEM nonfiction picture book which was just released from Millbrook Press (Carol Hinz, editor) on September 9, 2025". She is represented by Gaby Cabezut at The Seymour Agency. A published scientist, Danna's research has appeared in top scientific journals such as Science, Neuron, and PNAS. Formerly a biology professor and program director at Fisher College, she now focuses on writing for children. In our conversation Danna describes her transition from scientist to author, and the benefits that a career in science can bring to the writer's table. Learn more about your ad choices. Visit megaphone.fm/adchoices
Steve Brown's house burned down in a wildfire—and accidentally saved his life. When doctors missed his aggressive blood cancer for over a year, Steve built a swarm of AI agents that diagnosed it in minutes and helped design his treatment. Now he's turning that breakthrough into CureWise, a precision oncology platform helping cancer patients become better advocates. We explore agentic medicine, AI safety in healthcare, and how swarms of specialized AI agents are changing cancer care from diagnosis to treatment selection.
韓国Ulsan National Institute of Science and Technology (UNIST)で来年2月に独立するJHUの長濱さん(@k_hammer_1001 )再登場回。前回登場時からのアップデート。 (9/11 収録)Show Notes (番組HP):連絡先:https://bsky.app/profile/k-hammer.bsky.social ; https://x.com/k_hammer_1001 ; email: knagahama1001@gmail.com長濱さんNR初回登場回井上(昌俊)さんJung Hoや井上(昌)さんとの日本神経科学会でのシンポジウムシーズンオフ、ホットシーズン:アメリカのjob marketは大体8月後半-9月から翌年2-3月がjob openingの盛んなシーズンはんべー(Hyungbae Kwon)アポスティーユ公証人¬ary: 1 や 2犯罪歴証明書Kanghoon JungSynapShot論文:Son, Nagahama et al., Nat. Methods 2024; Dimerization-dependent fluorescent protein (ddFP)とsynapse organizer (Nlgn1とNrxn1β)を用いることで、可逆性がある蛍光シグナルをベースにシナプスの構造学的な変動を追跡していくツール。 Chuljung KwakGuo, Svoboda et al. マウス行動プロトコル論文シャンデリアセル+テクスチャ―の論文iTango2の論文GRASP, mGRASP, eGRASPGFP reconstitution across synaptic partners (GRASP): Feinberg et al., Neuron 2008 https://www.cell.com/AJHG/fulltext/S0896-6273(07)01020-3mGRASP: Kim, J. et al, Nat. Methods 2012 (Jeffrey C. Magee lab)eGRASP: 明るくしてvivoへの応用※同様のシナプス形成の可視化ツールとして、Sudhof labからのSynView: Tsetsenis et al., J. Neurosci. 2014 (https://www.jneurosci.org/content/34/45/15083.short)があります(長濱)Split-GFP: beta-barrel structure of GFP (1-10 & 11th 16残基, 215-230 amino acids)とsynapse organizerを組み合わせて、シナプス形成を可視化するツール。論文:https://www.nature.com/articles/nmeth932dimerization-dependent fluorescent protein (ddFP): 二つのモノマー(copy A & copy B)がヘテロダイマーを形成することで、蛍光を発色するタンパク質。Robert Campbell研で開発。論文1 (ddRFP): Alford et al., Cell Chemical Biology 2012 論文2 (ddGFP & ddYFP): Alford et al., ACS Synthetic Biology 2012 Won Do Heo※SynapShotの論文上では、IBS (Institute for Basic Science)で独立している Sangkyu Lee もco-corresponding authorになっています(長濱)OptoTrkBの論文: SynapShot論文でもFig. 3のdual-colorのimagingで使用。Small GTPaseの論文(optogenetic manipulation toolではなく、ddFPベースのbiosensorでした(長濱)):https://www.nature.com/articles/s41467-018-08217-3KAIST (Korea Advanced Institute of Science and Technology)Tobias MeyerMeyer研からBDRで独立した方:調べたら小長谷 有美さんでした。井上(Takanori Inoue)さんかんふんのescape behaviorの論文じょんほーのセロトニンの論文牧野さんの回小川さん; NR登場回ジョブハントでお世話になった方々: UTSWの藤田(Hirofumi Fujita)さん , OHIO-State の二本垣(Yuta Nihongaki)さん, 3人目は当然Jung Ho Hyun Future PI Slackかりごうさん回Referenceをお願いした方々: Paul Worley 狩野方伸先生 かりごう (Tomomi Karigo) さん 上阪さんNelson SprustonMax Planck: Max Planck Florida Institute for Neuroscience(MPFI)H-1BやJ1: アメリカのビザの種類。ポスドクは概ねJ1(交流訪問者ビザ)で渡米し、5年満期に達したところでH-1B(非移民就労ビザ)にビザ変更を行う。みんひゃお(Minhyeok Chang) すしアカデミーは70万円かかる4つあるIST (Institute of Science and Technology): UNIST, KAISTの他に、DGIST, GIST基本的には、USと似た方式でjob openingがある: 各大学・研究所がシーズン毎にtenure-track assistant professorのpositionを募集する。Soul National University(ソウル大学)Yonsei UniversityKorea University酒に頼りがち、ボルチモアクラフトビールKajikenDaikaya新潟大学脳研のシンポ三國さん藤島さんERC (European Research Council) starting grantK: アメリカのキャリアグラントのひとつであるK99のことScienceのcommentary: We started our Ph.D.s during COVID-19. Now, we're graduating into political chaosHigh BrainBong-Kiun KaangHee-Sup ShinEunjoon Kim IBS: Institute for Basic ScienceSebastien RoyerKIST (Korea Institute of Science and Technology) 韓国のGrant: National Research Foundation in Korea (NRF) がメイン。異なる時期にグラント締め切りあり。Korea Health Industry Development Institute (KHIDI) のようなAMEDに類似した団体もある。長濱ラボのバイオロジー:Biological commonalities across diverse psychiatric and neurological disordersSetd1aの論文Joshua A. GordonBipolar disorderとSchizophreniaがgeneticに似ている 1 2 3プレコックス感Nlgn3 KOマウスのケージメイトの行動異常論文長濱ラボ宣伝2026年2月から開設予定@Ulsan National Institute of Science and Technology (UNIST)Graduate School of Health Science and Technology (HST)大学院生は熱烈歓迎:https://admg-intl.unist.ac.kr/admissions/guidelines/2026 Spring 2nd 10/13/2025-10/22/20252026 Fall 4/6/2026-4/15/2026ポスドク:随時募集(予算次第ですが、興味がある方はお気軽にご連絡ください by長濱)Lab HPEditorial Notes:熱意のある大学院生・ポスドクの方々絶賛募集中です。ラボメンが皆それぞれにhappyでいられるような環境作りに向けて努力していく所存です。”日本に帰るつもりだったなら、医師免許使えよ”というツッコミは、自身に臨床医としての自覚が欠如しているため、お控えください(長濱)。韓国はインチョン空港にしか行ったことがないので、遊びに行くよい口実ができました(萩)独立おめでとうございます!日本が参考にすべきなのは、アメリカより欧州・アジアのやり方だとよく思うので、韓国アカデミアがどうやっているのかは非常に参考になりました。今後も色々伺うのが楽しみです!(脇)
What if our memories weren't fixed, but flexible? And what if the key to understanding fear, emotion, and consciousness lies in how the brain constantly reshapes experience?In this episode of Mind-Body Solution, Dr Tevin Naidu speaks with Prof Daniela Schiller, a world-renowned neuroscientist, and director of the Laboratory of Affective Neuroscience at Mount Sinai. Prof Schiller's groundbreaking work explores how we form, change, and even reimagine emotional memories, from the neuroscience of fear to the dynamic nature of consciousness and identity. Together, we dive into:- How fear memories are formed in the brain- Why emotional responses are flexible, not hardwired- The ethics of modifying traumatic memories- Social navigation: how the brain maps human relationships- The Human Affectome: a bold framework linking emotion and consciousness- Can machines ever be conscious? Free will, probabilities, and neuroscience- Memory as liberation: how to live with multiple stories of the selfProf Schiller is not only a world-leading neuroscientist with work published in Nature, Neuron, Nature Neuroscience, and PNAS, she's also a Fulbright Fellow, Kavli Frontiers of Science Fellow, two-time Moth StorySLAM winner, and drummer for the rock band "The Amygdaloids".TIMESTAMPS:(0:00) – Introduction: Daniela Schiller on the Science of Emotion & Memory(0:39) – From Animal Models to Human Fear Studies: Schiller's Journey(2:00) – What Happens in the Brain When a Fear Memory is Formed?(3:15) – Flexibility of Emotional Responses: Why Fear Is Not Hardwired(4:51) – Computational Psychiatry & the Brain as an Algorithmic System(6:00) – From Circuits to Consciousness: Can Neuroscience Explain Subjective Experience?(7:11) – The Human Affectome: A Framework Linking Emotion and Consciousness(9:13) – What Is Consciousness? Felt Experience as the Core of Mind(11:04) – Social Navigation: Mapping Human Relationships in the Brain(14:02) – How Social Media Distorts Real Interaction and Social Space(18:15) – Ethics of Modifying Traumatic Memories: Liberation or Risk?(21:27) – Are Emotions Brain Events, Bodily Events, or Psychological Phenomena?(23:16) – The 4E Approach: Embedded, Embodied, Enactive, and Extended Cognition(24:00) – Bringing Philosophy Into Neuroscience: The Human Affectome Project(27:03) – Exciting Advances: Intracranial Recordings, VR, and Naturalistic Neuroscience(33:11) – Can Artificial Intelligence or Machines Ever Be Conscious?(36:26) – Free Will and Probabilities: Neuroscience Meets Philosophy(41:12) – Overcoming Fear as Liberation: Redefining Memory and Identity(46:09) – Living With Multiple Stories: Memory, Authenticity, and Self-Creation(1:02:24) – Future Directions: Reconsolidation, Social Space, and the Human AffectomeEPISODE LINKS:- Daniela' Website: https://profiles.mountsinai.org/daniela-schiller- Daniela's Lab: https://labs.neuroscience.mssm.edu/project/schiller-lab/- Daniela's Publications: https://www.ncbi.nlm.nih.gov/myncbi/daniela.schiller.2/bibliography/public/CONNECT:- Website: https://tevinnaidu.com - Podcast: https://creators.spotify.com/pod/show/mindbodysolution- YouTube: https://youtube.com/mindbodysolution- Twitter: https://twitter.com/drtevinnaidu- Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu- LinkedIn: https://linkedin.com/in/drtevinnaidu=============================Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.
Illia Polosukhin, co-author of Attention Is All You Need and co-founder of NEAR Protocol, believes today's centralized AI ecosystem is broken. In this episode, he explains why User-Owned AI is the path forward — making systems private, verifiable, and aligned with users rather than corporations. We explore confidential computing, interoperable AI agents, and what a more sustainable AI future might really look like.Subscribe to The Neuron newsletter: https://www.theneurondaily.com
On this day of remembrance, we honor those lost and the lives forever changed by the events of 9/11. But beyond the history, there's something profound about how our bodies hold on to trauma—whether it's from a personal experience or a collective event that shook us all.
Most of us can agree: music is awesome. Regardless of which songs speak to you, music probably plays an important role in your life. The question is, what makes music so powerful? Why does a particular combination of sounds and rhythms grab us and affect us in the way that it does? And is it true that music can help heal patients with Alzheimer's, Parkinson's, PTSD, chronic pain, and more? To help us understand what we're learning about the neuroscience of music and how it can heal and enrich our lives, we're speaking with Daniel Levitin. He's a musician and a producer as well as a neuroscientist and bestselling author. His newest book is "I Heard There was a Secret Chord: Music As Medicine." Learn More:"I Heard There Was a Secret Chord" playlistMenon, V., & Levitin, D. J. (2005). The rewards of music listening: Response and connectivity of the mesolimbic system. NeuroImage.Menon, V. (2023). 20 years of the default mode network: A review and synthesis. Neuron.Salimpoor, V. N., et al. (2013). Interactions between the nucleus accumbens and auditory cortices predict music's reward value. Science.Wang, L., Peng, J.-l., et al. (2022). Effects of rhythmic auditory stimulation on gait and motor function in Parkinson's disease: Systematic review & meta-analysis. Frontiers in Neurology.Zumbansen, A., et al. (2014). Melodic Intonation Therapy: Back to basics for future research. Frontiers in Neurology.Moreno-Morales et al. (2020). Music therapy in the treatment of dementia: Systematic review & meta-analysis. Frontiers in Medicine.Allen, E. J., et al. (2017). Representations of pitch and timbre variation in human auditory cortex. Journal of Neuroscience.Sonos/Apple “Music Makes It Home” study (2016). "This Speaker Company Says Music Makes You Happier." Time Magazine.We want to hear from your neurons! Email us at at neuronspodcast@stanford.eduSend us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.
Thomson Reuters just launched Deep Research—an AI system that doesn't just search legal databases, but plans and strategizes like an experienced attorney. In this episode, we explore how one of the world's largest legal research companies is using AI agents to transform how lawyers work, the challenges of building AI for high-stakes legal decisions, and what this means for the future of knowledge work. CTO Joel Hron shares insights from testing with 1,200+ customers, tackling hallucination risks in legal settings, and building professional-grade AI systems.Resources mentioned: Thomson Reuters Deep Research: https://www.prnewswire.com/news-releases/thomson-reuters-launches-cocounsel-legal-transforming-legal-work-with-agentic-ai-and-deep-research-302521761.html Westlaw & KeyCite: https://legal.thomsonreuters.com/en/products/westlaw/keycite Claude Code for development: https://www.anthropic.com/claude-code LinkedIn: Joel HronThomson Reuters Medium blog: https://medium.com/tr-labs-ml-engineering-blog Subscribe to The Neuron newsletter: https://theneuron.ai
Vincent and Daniel discuss research showing that Toxoplasma gondii infection of the brain alters extracellular vesicle production and the communication between neurons and astrocytes. Hosts: Vincent Racaniello and Daniel Griffin Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server T. gondii infection of neurons (PLoS Path) Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees
Today we go deeper on Google's AI stack with Logan Kilpatrick: what AI Studio is great at, how it fits with Firebase/Colab/Gemini CLI/Jules, and where "thinking" models make sense. We cover real-world workflows—from game prototyping and screen-share assistance to legal/privacy basics and on-device micro-apps. Logan shares his insights on vibe coding, the future of AI development, and Google's open-source strategy with Gemma models.Resources mentioned:Google AI Studio: https://aistudio.google.com/Gemini CLI: https://github.com/google-gemini/gemini-cliKaggle Game Arena: https://www.kaggle.com/competitionsGoogle Firebase: https://firebase.google.com/Gemma models: https://ai.google.dev/gemmaSubscribe to The Neuron newsletter: https://theneuron.ai
Jde o průlom v zubní medicíně? - Projekt expedice Neuron povede český tým do guatemalských hor za evolučním zázrakem. Tým mladých vědců se v listopadu vydá do různých ekosystémů Guatemaly prozkoumat kutilky, konkrétně jejich hnízdění a sociální chování. - Jak se mění a vyvíjí tvorba krevních buněk u novorozenců - tuto dosud ne úplně probádanou oblast zkoumali čeští vědci. Co jejich výzkum odhalil? Moderuje Naděžda Hávová.
What does it take to steer a 3,500-person company into the age of generative AI? ZoomInfo founder and CEO Henry Schuck joins us to unpack the company's journey from data powerhouse to AI-first GTM platform, the cultural shifts that enabled it, and the hard-won lessons any leader can borrow. We explore how they reduced teams from 26 to 2 people using AI agents, why 2/3 of employees now use AI daily, and the critical role of data infrastructure in AI success.Subscribe to The Neuron newsletter: https://theneuron.aiLearn more about ZoomInfo: https://www.zoominfo.com
Did you know that real human connection—not supplements, superfoods, or workouts—is one of the most powerful ways to protect your brain? In this episode of Happy and Healthy with Amy Lang, we dive into the science behind social connection and why it's essential for women in midlife who want to protect their cognitive health.What to Listen For:[01:25] The New York Times article that sparked this episode[02:05] What makes “Super Agers” cognitively younger than their peers[03:00] Brene Brown's definition of real connection[03:45] Why your brain is biologically wired to bond with others[04:10] What the longest-running study on adult development reveals about relationships and brain health[05:05] The devastating effects of loneliness—equal to smoking 15 cigarettes a day[06:30] What is social homeostasis and why it matters for your brain[07:20] How isolation rewires the brain and leads to cognitive decline[10:55] The 3 layers of social connection: inner circle, common clusters, and micro-interactions[14:00] 4 actionable strategies (plus a bonus!) to start building brain-supportive connections todayProtecting your brain doesn't have to be complicated. Real, authentic human connection is one of the most powerful tools we have—and it's free. In this episode, I shared how you can start strengthening your brain through relationships today. Be sure to subscribe to Happy and Healthy with Amy Lang, and don't forget to join the priority list for Second Spring Society (moxie-club.com/society), our upcoming membership for women in midlife who want to thrive together.Sources:Waldinger, R., & Schulz, M. (2023). The Good Life: Lessons from the World's Longest Scientific Study of Happiness. Simon & Schuster.Holt-Lunstad, J., Smith, T. B., & Layton, J. B. (2010). Social Relationships and Mortality Risk: A Meta-analytic Review. PLOS Medicine.Liu, D., & Tye, K. (2021). Neural mechanisms of social homeostasis. Neuron.Sepúlveda-Loyola, W., et al. (2020). Impact of Social Isolation Due to COVID-19 on Health in Older People: Mental and Physical Effects and Recommendations. Journal of Nutrition, Health & Aging.Lara, B., et al. (2021). Neuropsychiatric symptoms and quality of life in Alzheimer's patients before and during lockdown. International Psychogeriatrics.Brown, B. (2010). The Power of Vulnerability. TEDx Houston.Dr K (Dr. Alok Kanojia), Healthy Gamer GG. I Don't Know How to Build Relationships: https://www.youtube.com/watch?v=yfWVQ25UmEQ Cole, T. (2021). Boundary Boss: The Essential Guide to Talk True, Be Seen, and (Finally) Live Free. Sounds True.RESOURCES: Register for the FREE Masterclass: 5 Keys to Protecting Your Brain Health Book a FREE Discovery Call with Amy Lang Order Amy's book Thoughts Are Habits Too: Master Your Triggers, Free Yourself From Diet Culture, and Rediscover Joyful Eating. Follow Amy on Instagram @habitwhisperer
What does "AI governance" really entail, and why does it matter right now? Credo AI founder Navrina Singh joins The Neuron to unpack risk buckets, Model Trust Scores, and the regulatory zig-zag between the EU and the U.S.—so you can move fast without crashing the car. We dive into open source safety, agent governance, and test OpenAI's brand new open source model live.Learn more about AI governance: https://credo.ai/resourcesSubscribe to The Neuron newsletter: https://theneuron.ai
A lot of people aren't sure whether they should just chat with an AI model, craft a structured prompt, spin up a project, or unleash a full-blown agent. In this episode, we break down the differences between these approaches and share a practical decision-making framework. We'll show how simple prompts excel for quick, isolated tasks, why structured prompts improve clarity and focus, when a project (workflow) is better for predictable, repeatable processes, and where autonomous agents shine for dynamic, open-ended problems. Along the way we'll demo real examples, share tips for avoiding unnecessary complexity, and help listeners decide which tool fits their use case.Subscribe to The Neuron newsletter: https://theneuron.ai
In 1985, Coca-Cola changed its flavour. You probably know that this was a complete failure. ‘New Coke' was discontinued after just 79 days. But you probably don't know the true reason why New Coke failed. Many claim it was due to poor market research, but today's guest on Nudge, leading consumer behaviour expert Philip Graves, disagrees. Philip says New Coke failed not because the research was poor, but because market research is inherently flawed. Want to understand the biggest marketing blunder of the century? Listen to today's Nudge. --- Phil's book: https://shorturl.at/kzAta Phil's consultancy: https://www.philipgraves.net/consultancy/ Subscribe to the (free) Nudge Newsletter: https://nudge.ck.page/profile Connect on LinkedIn: https://www.linkedin.com/in/phill-agnew-22213187/ Watch Nudge on YouTube: https://www.youtube.com/@nudgepodcast/ --- Today's sources: Dutton, D. G., & Aron, A. P. (1974). Some evidence for heightened sexual attraction under conditions of high anxiety. Journal of Personality and Social Psychology, 30(4), 510–517. Graves, P. (2010). Consumer.ology: The market research myth, the truth about consumers and the psychology of shopping. Nicholas Brealey. Hasel, L.E. & Kassin, S.M. (2009). On the presumption of evidentiary independence: Can confessions corrupt eyewitness identifications? Psychological Science, 20(1), 122. McClure, S. M., Li, J., Tomlin, D., Cypert, K. S., Montague, L. M., & Montague, P. R. (2004). Neural correlates of behavioral preference for culturally familiar drinks. Neuron, 44(2), 379–387. Nisbett, R. E., & Wilson, T. D. (1977). Telling more than we can know: Verbal reports on mental processes. Psychological Review, 84(3), 231–259.
Sabine VdL talks to Lou Smith, a true trailblazer in the world of financial services and insurance. In today's episode, we'll dive into Lou's incredible journey, explore the vision behind Neuron, and discuss the key takeaways from the latest report that insurance providers need to consider. KEY TAKEAWAYS We all have moments in life where the last thing we want to look at is out credit rating and history, but those things can affect how you access financial services in the future. Lou was part of the team that delivered the first end-to-end mortgage renewal online, started to break down investments and getting it to the hands of the many rather than the few. Everybody says insurance is behind the rest of the financial services industry, and it's a funny statement. It doesn't matter. What I'm seeing in insurance in the last 5-6 years is that this conversation has circled around about what do we do? But in the last 12-18 months I've seen a passion for how do now think about using digital, distribution models, digital, analytics and AI and thinking of all of those things together and deliver distribution models that start to move industry forward. The challenge is always in leadership, culture and change adoption. This is because it's really difficult to step into an unknown and think it's going to be better than what you're doing today. You want to power people with the data and capabilities so they can do what they're brilliant at, which is focusing on the best product and position for their client. Neuron and others enable brokers to do that. You also want to attract a new generation into the brokering sector, but rather than have them focus on the admin of that sector, they should be having great conversations with clients. All the work we're doing enables brokers to do that. BEST MOMENTS ‘When starting my career I had a real passion for how to make the services we were offering more successful for clients and customers.'‘We care about the customer and making financial data accessible to you through the narratives we use.'‘I'd love to say this was all planned out, we didn't call it anything or know what it looked like, we just started to bring data and technologies together to build ‘workflow' and that's now become cool.'‘We want to be the easiest, most predictable and consistent broker to work with.' ABOUT THE GUEST Louise (or Lou) Smith is a trailblazer in the financial services and insurance industries, with a career spanning leadership roles across digital transformation, data, product innovation, distribution, technology, and operations. Her journey has been marked by groundbreaking achievements, including delivering the UK's first steps into digital distribution at Barclays, leading the digital transformation of the Royal Bank of Scotland (including NatWest) during its turnaround to profitability, and becoming the first-ever Chief Digital Officer at Lloyd's of London. Currently, Louise is at the helm of Neuron, a transformative initiative aimed at redefining the insurance and financial services landscape. Through Neuron, she is driving innovation, collaboration, and growth, focusing on creating a more connected and customer-centric industry. WTWCO LinkedIn ABOUT THE HOST Sabine is a corporate strategist turned entrepreneur. She is the CEO and Managing Partner of Alchemy Crew a venture lab that accelerates the curation, validation, & commercialization of new tech business models. Sabine is renowned within the insurance sector for building some of the most renowned tech startup accelerators around the world working with over 30 corporate insurers, accelerated over 100 startup ventures. Sabine is the co-editor of the bestseller The INSURTECH Book, a top 50 Women in Tech, a FinTech and InsurTech Influencer, an investor & multi-award winner. Twitter LinkedIn Instagram Facebook TikTok Email Website This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/