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Microsoft AI CEO Mustafa Suleyman (co-founder of DeepMind) joins The Neuron to discuss his provocative essay on "Seemingly Conscious AI" and why machines that mimic consciousness pose unprecedented risks - even when they're not actually alive. We explore how 700 million people are already using AI as life coaches, Microsoft's massive $208B revenue strategy for AI, and exclusive features like Copilot Vision that can see everything you see in real-time.Key topics:• Why AI consciousness is an illusion - and why that's dangerous • Microsoft's 2 gigawatt datacenter expansion (2.5x Seattle's power usage)• MAI-1 Preview breaking into the top 10 models globally• The future of AI browsers and autonomous agents• Why granting AI rights could threaten humanitySubscribe to The Neuron newsletter (580,000+ readers): https://theneuron.aiResources mentioned:• Mustafa's essay "Seemingly Conscious AI Is Coming" https://mustafa-suleyman.ai/seemingly...• Try Copilot Vision: https://copilot.microsoft.com• Microsoft Edge AI features: https://www.microsoft.com/en-us/edge• MAI-1 Preview models: https://microsoft.ai/news/two-new-in-...Special thanks to today's sponsor, Wispr Flow: https://wisprflow.ai/neuron
In our wonderful interview, Dr. Danna Trachtenberg Zeiger and I celebrate her debut picture book, Rewriting the Rules, a STEM nonfiction picture book which was just released from Millbrook Press (Carol Hinz, editor) on September 9, 2025". She is represented by Gaby Cabezut at The Seymour Agency. A published scientist, Danna's research has appeared in top scientific journals such as Science, Neuron, and PNAS. Formerly a biology professor and program director at Fisher College, she now focuses on writing for children. In our conversation Danna describes her transition from scientist to author, and the benefits that a career in science can bring to the writer's table. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
In our wonderful interview, Dr. Danna Trachtenberg Zeiger and I celebrate her debut picture book, Rewriting the Rules, a STEM nonfiction picture book which was just released from Millbrook Press (Carol Hinz, editor) on September 9, 2025". She is represented by Gaby Cabezut at The Seymour Agency. A published scientist, Danna's research has appeared in top scientific journals such as Science, Neuron, and PNAS. Formerly a biology professor and program director at Fisher College, she now focuses on writing for children. In our conversation Danna describes her transition from scientist to author, and the benefits that a career in science can bring to the writer's table. Learn more about your ad choices. Visit megaphone.fm/adchoices
Steve Brown's house burned down in a wildfire—and accidentally saved his life. When doctors missed his aggressive blood cancer for over a year, Steve built a swarm of AI agents that diagnosed it in minutes and helped design his treatment. Now he's turning that breakthrough into CureWise, a precision oncology platform helping cancer patients become better advocates. We explore agentic medicine, AI safety in healthcare, and how swarms of specialized AI agents are changing cancer care from diagnosis to treatment selection.
韓国Ulsan National Institute of Science and Technology (UNIST)で来年2月に独立するJHUの長濱さん(@k_hammer_1001 )再登場回。前回登場時からのアップデート。 (9/11 収録)Show Notes (番組HP):連絡先:https://bsky.app/profile/k-hammer.bsky.social ; https://x.com/k_hammer_1001 ; email: knagahama1001@gmail.com長濱さんNR初回登場回井上(昌俊)さんJung Hoや井上(昌)さんとの日本神経科学会でのシンポジウムシーズンオフ、ホットシーズン:アメリカのjob marketは大体8月後半-9月から翌年2-3月がjob openingの盛んなシーズンはんべー(Hyungbae Kwon)アポスティーユ公証人¬ary: 1 や 2犯罪歴証明書Kanghoon JungSynapShot論文:Son, Nagahama et al., Nat. Methods 2024; Dimerization-dependent fluorescent protein (ddFP)とsynapse organizer (Nlgn1とNrxn1β)を用いることで、可逆性がある蛍光シグナルをベースにシナプスの構造学的な変動を追跡していくツール。 Chuljung KwakGuo, Svoboda et al. マウス行動プロトコル論文シャンデリアセル+テクスチャ―の論文iTango2の論文GRASP, mGRASP, eGRASPGFP reconstitution across synaptic partners (GRASP): Feinberg et al., Neuron 2008 https://www.cell.com/AJHG/fulltext/S0896-6273(07)01020-3mGRASP: Kim, J. et al, Nat. Methods 2012 (Jeffrey C. Magee lab)eGRASP: 明るくしてvivoへの応用※同様のシナプス形成の可視化ツールとして、Sudhof labからのSynView: Tsetsenis et al., J. Neurosci. 2014 (https://www.jneurosci.org/content/34/45/15083.short)があります(長濱)Split-GFP: beta-barrel structure of GFP (1-10 & 11th 16残基, 215-230 amino acids)とsynapse organizerを組み合わせて、シナプス形成を可視化するツール。論文:https://www.nature.com/articles/nmeth932dimerization-dependent fluorescent protein (ddFP): 二つのモノマー(copy A & copy B)がヘテロダイマーを形成することで、蛍光を発色するタンパク質。Robert Campbell研で開発。論文1 (ddRFP): Alford et al., Cell Chemical Biology 2012 論文2 (ddGFP & ddYFP): Alford et al., ACS Synthetic Biology 2012 Won Do Heo※SynapShotの論文上では、IBS (Institute for Basic Science)で独立している Sangkyu Lee もco-corresponding authorになっています(長濱)OptoTrkBの論文: SynapShot論文でもFig. 3のdual-colorのimagingで使用。Small GTPaseの論文(optogenetic manipulation toolではなく、ddFPベースのbiosensorでした(長濱)):https://www.nature.com/articles/s41467-018-08217-3KAIST (Korea Advanced Institute of Science and Technology)Tobias MeyerMeyer研からBDRで独立した方:調べたら小長谷 有美さんでした。井上(Takanori Inoue)さんかんふんのescape behaviorの論文じょんほーのセロトニンの論文牧野さんの回小川さん; NR登場回ジョブハントでお世話になった方々: UTSWの藤田(Hirofumi Fujita)さん , OHIO-State の二本垣(Yuta Nihongaki)さん, 3人目は当然Jung Ho Hyun Future PI Slackかりごうさん回Referenceをお願いした方々: Paul Worley 狩野方伸先生 かりごう (Tomomi Karigo) さん 上阪さんNelson SprustonMax Planck: Max Planck Florida Institute for Neuroscience(MPFI)H-1BやJ1: アメリカのビザの種類。ポスドクは概ねJ1(交流訪問者ビザ)で渡米し、5年満期に達したところでH-1B(非移民就労ビザ)にビザ変更を行う。みんひゃお(Minhyeok Chang) すしアカデミーは70万円かかる4つあるIST (Institute of Science and Technology): UNIST, KAISTの他に、DGIST, GIST基本的には、USと似た方式でjob openingがある: 各大学・研究所がシーズン毎にtenure-track assistant professorのpositionを募集する。Soul National University(ソウル大学)Yonsei UniversityKorea University酒に頼りがち、ボルチモアクラフトビールKajikenDaikaya新潟大学脳研のシンポ三國さん藤島さんERC (European Research Council) starting grantK: アメリカのキャリアグラントのひとつであるK99のことScienceのcommentary: We started our Ph.D.s during COVID-19. Now, we're graduating into political chaosHigh BrainBong-Kiun KaangHee-Sup ShinEunjoon Kim IBS: Institute for Basic ScienceSebastien RoyerKIST (Korea Institute of Science and Technology) 韓国のGrant: National Research Foundation in Korea (NRF) がメイン。異なる時期にグラント締め切りあり。Korea Health Industry Development Institute (KHIDI) のようなAMEDに類似した団体もある。長濱ラボのバイオロジー:Biological commonalities across diverse psychiatric and neurological disordersSetd1aの論文Joshua A. GordonBipolar disorderとSchizophreniaがgeneticに似ている 1 2 3プレコックス感Nlgn3 KOマウスのケージメイトの行動異常論文長濱ラボ宣伝2026年2月から開設予定@Ulsan National Institute of Science and Technology (UNIST)Graduate School of Health Science and Technology (HST)大学院生は熱烈歓迎:https://admg-intl.unist.ac.kr/admissions/guidelines/2026 Spring 2nd 10/13/2025-10/22/20252026 Fall 4/6/2026-4/15/2026ポスドク:随時募集(予算次第ですが、興味がある方はお気軽にご連絡ください by長濱)Lab HPEditorial Notes:熱意のある大学院生・ポスドクの方々絶賛募集中です。ラボメンが皆それぞれにhappyでいられるような環境作りに向けて努力していく所存です。”日本に帰るつもりだったなら、医師免許使えよ”というツッコミは、自身に臨床医としての自覚が欠如しているため、お控えください(長濱)。韓国はインチョン空港にしか行ったことがないので、遊びに行くよい口実ができました(萩)独立おめでとうございます!日本が参考にすべきなのは、アメリカより欧州・アジアのやり方だとよく思うので、韓国アカデミアがどうやっているのかは非常に参考になりました。今後も色々伺うのが楽しみです!(脇)
What if our memories weren't fixed, but flexible? And what if the key to understanding fear, emotion, and consciousness lies in how the brain constantly reshapes experience?In this episode of Mind-Body Solution, Dr Tevin Naidu speaks with Prof Daniela Schiller, a world-renowned neuroscientist, and director of the Laboratory of Affective Neuroscience at Mount Sinai. Prof Schiller's groundbreaking work explores how we form, change, and even reimagine emotional memories, from the neuroscience of fear to the dynamic nature of consciousness and identity. Together, we dive into:- How fear memories are formed in the brain- Why emotional responses are flexible, not hardwired- The ethics of modifying traumatic memories- Social navigation: how the brain maps human relationships- The Human Affectome: a bold framework linking emotion and consciousness- Can machines ever be conscious? Free will, probabilities, and neuroscience- Memory as liberation: how to live with multiple stories of the selfProf Schiller is not only a world-leading neuroscientist with work published in Nature, Neuron, Nature Neuroscience, and PNAS, she's also a Fulbright Fellow, Kavli Frontiers of Science Fellow, two-time Moth StorySLAM winner, and drummer for the rock band "The Amygdaloids".TIMESTAMPS:(0:00) – Introduction: Daniela Schiller on the Science of Emotion & Memory(0:39) – From Animal Models to Human Fear Studies: Schiller's Journey(2:00) – What Happens in the Brain When a Fear Memory is Formed?(3:15) – Flexibility of Emotional Responses: Why Fear Is Not Hardwired(4:51) – Computational Psychiatry & the Brain as an Algorithmic System(6:00) – From Circuits to Consciousness: Can Neuroscience Explain Subjective Experience?(7:11) – The Human Affectome: A Framework Linking Emotion and Consciousness(9:13) – What Is Consciousness? Felt Experience as the Core of Mind(11:04) – Social Navigation: Mapping Human Relationships in the Brain(14:02) – How Social Media Distorts Real Interaction and Social Space(18:15) – Ethics of Modifying Traumatic Memories: Liberation or Risk?(21:27) – Are Emotions Brain Events, Bodily Events, or Psychological Phenomena?(23:16) – The 4E Approach: Embedded, Embodied, Enactive, and Extended Cognition(24:00) – Bringing Philosophy Into Neuroscience: The Human Affectome Project(27:03) – Exciting Advances: Intracranial Recordings, VR, and Naturalistic Neuroscience(33:11) – Can Artificial Intelligence or Machines Ever Be Conscious?(36:26) – Free Will and Probabilities: Neuroscience Meets Philosophy(41:12) – Overcoming Fear as Liberation: Redefining Memory and Identity(46:09) – Living With Multiple Stories: Memory, Authenticity, and Self-Creation(1:02:24) – Future Directions: Reconsolidation, Social Space, and the Human AffectomeEPISODE LINKS:- Daniela' Website: https://profiles.mountsinai.org/daniela-schiller- Daniela's Lab: https://labs.neuroscience.mssm.edu/project/schiller-lab/- Daniela's Publications: https://www.ncbi.nlm.nih.gov/myncbi/daniela.schiller.2/bibliography/public/CONNECT:- Website: https://tevinnaidu.com - Podcast: https://creators.spotify.com/pod/show/mindbodysolution- YouTube: https://youtube.com/mindbodysolution- Twitter: https://twitter.com/drtevinnaidu- Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu- LinkedIn: https://linkedin.com/in/drtevinnaidu=============================Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.
Illia Polosukhin, co-author of Attention Is All You Need and co-founder of NEAR Protocol, believes today's centralized AI ecosystem is broken. In this episode, he explains why User-Owned AI is the path forward — making systems private, verifiable, and aligned with users rather than corporations. We explore confidential computing, interoperable AI agents, and what a more sustainable AI future might really look like.Subscribe to The Neuron newsletter: https://www.theneurondaily.com
On this day of remembrance, we honor those lost and the lives forever changed by the events of 9/11. But beyond the history, there's something profound about how our bodies hold on to trauma—whether it's from a personal experience or a collective event that shook us all.
Elsa Fouragnan is an Associate Professor and UKRI Future Leader Fellow at the University of Plymouth. We talk mainly about her work on focussed transcranial ultrasound stimulation, a new non-invasive way other stimulating (human) brains, including deep areas that can't be reached with TMS. We also discuss her childhood in French Polynesia, how she started doing research, what it's like seeing a brain during surgery, and much more.This was the first episode I recorded in-person. The audio quality is really good, with the minor exception that I made a really silly error during editing, such that quiet parts are sometimes not entirely audible. A few words are not audible, but this shouldn't affect comprehension.BJKS Podcast is a podcast about neuroscience, psychology, and anything vaguely related, hosted by Benjamin James Kuper-Smith.Support the show: https://geni.us/bjks-patreonTimestamps0:00:00: Elsa's childhood in French Polynesia and in mainland France0:10:25: Why Elsa studied engineering and started doing research0:19:04: How Elsa started working on Transcranial Focused Ultrasound Stimulation0:23:08: What is Transcranial Focused Ultrasound Stimulation?0:28:20: Is it safe?0:36:12: What can you do with it/what kind of stimulations is it?0:53:41: The practicalities of using TUS1:04:42: What it's like to see brain surgery in the operating theatre1:10:11: Back to the skull being a problem and which brains regions can be reached with TUS?1:18:49: The future of TUS1:27:59: A book or paper more people should read1:30:13: Something Elsa wishes she'd learnt sooner1:34:51: Advice for PhD students/postdocsPodcast linksWebsite: https://geni.us/bjks-podBlueSky: https://geni.us/pod-bskyElsa's linksWebsite: https://geni.us/fouragnan-webGoogle Scholar: https://geni.us/fouragnan-scholarBlueSky: https://geni.us/fouragnan-bskyBen's linksWebsite: https://geni.us/bjks-webGoogle Scholar: https://geni.us/bjks-scholarBlueSky: https://geni.us/bjks-bskyReferences and linksUa Pou: https://en.wikipedia.org/wiki/Ua_PouFolloni, Verhagen, Mars, Fouragnan, ... & Sallet (2019). Manipulation of subcortical and deep cortical activity in the primate brain using transcranial focused ultrasound stimulation. Neuron.Liptrot (2015). The Outrun.Murphy & Fouragnan (2024). The future of transcranial ultrasound as a precision brain interface. PLoS Biology.Yoo, Mittelstein, Hurt, Lacroix & Shapiro (2022). Focused ultrasound excites cortical neurons via mechanosensitive calcium accumulation and ion channel amplification. Nature Communications.Yaakub, ... & Fouragnan (2024). Non-invasive Ultrasound Deep Neuromodulation of the Human Nucleus Accumbens Increases Win-Stay Behaviour. BioRxiv.
Most of us can agree: music is awesome. Regardless of which songs speak to you, music probably plays an important role in your life. The question is, what makes music so powerful? Why does a particular combination of sounds and rhythms grab us and affect us in the way that it does? And is it true that music can help heal patients with Alzheimer's, Parkinson's, PTSD, chronic pain, and more? To help us understand what we're learning about the neuroscience of music and how it can heal and enrich our lives, we're speaking with Daniel Levitin. He's a musician and a producer as well as a neuroscientist and bestselling author. His newest book is "I Heard There was a Secret Chord: Music As Medicine." Learn More:"I Heard There Was a Secret Chord" playlistMenon, V., & Levitin, D. J. (2005). The rewards of music listening: Response and connectivity of the mesolimbic system. NeuroImage.Menon, V. (2023). 20 years of the default mode network: A review and synthesis. Neuron.Salimpoor, V. N., et al. (2013). Interactions between the nucleus accumbens and auditory cortices predict music's reward value. Science.Wang, L., Peng, J.-l., et al. (2022). Effects of rhythmic auditory stimulation on gait and motor function in Parkinson's disease: Systematic review & meta-analysis. Frontiers in Neurology.Zumbansen, A., et al. (2014). Melodic Intonation Therapy: Back to basics for future research. Frontiers in Neurology.Moreno-Morales et al. (2020). Music therapy in the treatment of dementia: Systematic review & meta-analysis. Frontiers in Medicine.Allen, E. J., et al. (2017). Representations of pitch and timbre variation in human auditory cortex. Journal of Neuroscience.Sonos/Apple “Music Makes It Home” study (2016). "This Speaker Company Says Music Makes You Happier." Time Magazine.We want to hear from your neurons! Email us at at neuronspodcast@stanford.eduSend us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.
Thomson Reuters just launched Deep Research—an AI system that doesn't just search legal databases, but plans and strategizes like an experienced attorney. In this episode, we explore how one of the world's largest legal research companies is using AI agents to transform how lawyers work, the challenges of building AI for high-stakes legal decisions, and what this means for the future of knowledge work. CTO Joel Hron shares insights from testing with 1,200+ customers, tackling hallucination risks in legal settings, and building professional-grade AI systems.Resources mentioned: Thomson Reuters Deep Research: https://www.prnewswire.com/news-releases/thomson-reuters-launches-cocounsel-legal-transforming-legal-work-with-agentic-ai-and-deep-research-302521761.html Westlaw & KeyCite: https://legal.thomsonreuters.com/en/products/westlaw/keycite Claude Code for development: https://www.anthropic.com/claude-code LinkedIn: Joel HronThomson Reuters Medium blog: https://medium.com/tr-labs-ml-engineering-blog Subscribe to The Neuron newsletter: https://theneuron.ai
Vincent and Daniel discuss research showing that Toxoplasma gondii infection of the brain alters extracellular vesicle production and the communication between neurons and astrocytes. Hosts: Vincent Racaniello and Daniel Griffin Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server T. gondii infection of neurons (PLoS Path) Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees
Today we go deeper on Google's AI stack with Logan Kilpatrick: what AI Studio is great at, how it fits with Firebase/Colab/Gemini CLI/Jules, and where "thinking" models make sense. We cover real-world workflows—from game prototyping and screen-share assistance to legal/privacy basics and on-device micro-apps. Logan shares his insights on vibe coding, the future of AI development, and Google's open-source strategy with Gemma models.Resources mentioned:Google AI Studio: https://aistudio.google.com/Gemini CLI: https://github.com/google-gemini/gemini-cliKaggle Game Arena: https://www.kaggle.com/competitionsGoogle Firebase: https://firebase.google.com/Gemma models: https://ai.google.dev/gemmaSubscribe to The Neuron newsletter: https://theneuron.ai
Jde o průlom v zubní medicíně? - Projekt expedice Neuron povede český tým do guatemalských hor za evolučním zázrakem. Tým mladých vědců se v listopadu vydá do různých ekosystémů Guatemaly prozkoumat kutilky, konkrétně jejich hnízdění a sociální chování. - Jak se mění a vyvíjí tvorba krevních buněk u novorozenců - tuto dosud ne úplně probádanou oblast zkoumali čeští vědci. Co jejich výzkum odhalil? Moderuje Naděžda Hávová.
What does it take to steer a 3,500-person company into the age of generative AI? ZoomInfo founder and CEO Henry Schuck joins us to unpack the company's journey from data powerhouse to AI-first GTM platform, the cultural shifts that enabled it, and the hard-won lessons any leader can borrow. We explore how they reduced teams from 26 to 2 people using AI agents, why 2/3 of employees now use AI daily, and the critical role of data infrastructure in AI success.Subscribe to The Neuron newsletter: https://theneuron.aiLearn more about ZoomInfo: https://www.zoominfo.com
Did you know that real human connection—not supplements, superfoods, or workouts—is one of the most powerful ways to protect your brain? In this episode of Happy and Healthy with Amy Lang, we dive into the science behind social connection and why it's essential for women in midlife who want to protect their cognitive health.What to Listen For:[01:25] The New York Times article that sparked this episode[02:05] What makes “Super Agers” cognitively younger than their peers[03:00] Brene Brown's definition of real connection[03:45] Why your brain is biologically wired to bond with others[04:10] What the longest-running study on adult development reveals about relationships and brain health[05:05] The devastating effects of loneliness—equal to smoking 15 cigarettes a day[06:30] What is social homeostasis and why it matters for your brain[07:20] How isolation rewires the brain and leads to cognitive decline[10:55] The 3 layers of social connection: inner circle, common clusters, and micro-interactions[14:00] 4 actionable strategies (plus a bonus!) to start building brain-supportive connections todayProtecting your brain doesn't have to be complicated. Real, authentic human connection is one of the most powerful tools we have—and it's free. In this episode, I shared how you can start strengthening your brain through relationships today. Be sure to subscribe to Happy and Healthy with Amy Lang, and don't forget to join the priority list for Second Spring Society (moxie-club.com/society), our upcoming membership for women in midlife who want to thrive together.Sources:Waldinger, R., & Schulz, M. (2023). The Good Life: Lessons from the World's Longest Scientific Study of Happiness. Simon & Schuster.Holt-Lunstad, J., Smith, T. B., & Layton, J. B. (2010). Social Relationships and Mortality Risk: A Meta-analytic Review. PLOS Medicine.Liu, D., & Tye, K. (2021). Neural mechanisms of social homeostasis. Neuron.Sepúlveda-Loyola, W., et al. (2020). Impact of Social Isolation Due to COVID-19 on Health in Older People: Mental and Physical Effects and Recommendations. Journal of Nutrition, Health & Aging.Lara, B., et al. (2021). Neuropsychiatric symptoms and quality of life in Alzheimer's patients before and during lockdown. International Psychogeriatrics.Brown, B. (2010). The Power of Vulnerability. TEDx Houston.Dr K (Dr. Alok Kanojia), Healthy Gamer GG. I Don't Know How to Build Relationships: https://www.youtube.com/watch?v=yfWVQ25UmEQ Cole, T. (2021). Boundary Boss: The Essential Guide to Talk True, Be Seen, and (Finally) Live Free. Sounds True.RESOURCES: Register for the FREE Masterclass: 5 Keys to Protecting Your Brain Health Book a FREE Discovery Call with Amy Lang Order Amy's book Thoughts Are Habits Too: Master Your Triggers, Free Yourself From Diet Culture, and Rediscover Joyful Eating. Follow Amy on Instagram @habitwhisperer
What does "AI governance" really entail, and why does it matter right now? Credo AI founder Navrina Singh joins The Neuron to unpack risk buckets, Model Trust Scores, and the regulatory zig-zag between the EU and the U.S.—so you can move fast without crashing the car. We dive into open source safety, agent governance, and test OpenAI's brand new open source model live.Learn more about AI governance: https://credo.ai/resourcesSubscribe to The Neuron newsletter: https://theneuron.ai
A lot of people aren't sure whether they should just chat with an AI model, craft a structured prompt, spin up a project, or unleash a full-blown agent. In this episode, we break down the differences between these approaches and share a practical decision-making framework. We'll show how simple prompts excel for quick, isolated tasks, why structured prompts improve clarity and focus, when a project (workflow) is better for predictable, repeatable processes, and where autonomous agents shine for dynamic, open-ended problems. Along the way we'll demo real examples, share tips for avoiding unnecessary complexity, and help listeners decide which tool fits their use case.Subscribe to The Neuron newsletter: https://theneuron.ai
In 1985, Coca-Cola changed its flavour. You probably know that this was a complete failure. ‘New Coke' was discontinued after just 79 days. But you probably don't know the true reason why New Coke failed. Many claim it was due to poor market research, but today's guest on Nudge, leading consumer behaviour expert Philip Graves, disagrees. Philip says New Coke failed not because the research was poor, but because market research is inherently flawed. Want to understand the biggest marketing blunder of the century? Listen to today's Nudge. --- Phil's book: https://shorturl.at/kzAta Phil's consultancy: https://www.philipgraves.net/consultancy/ Subscribe to the (free) Nudge Newsletter: https://nudge.ck.page/profile Connect on LinkedIn: https://www.linkedin.com/in/phill-agnew-22213187/ Watch Nudge on YouTube: https://www.youtube.com/@nudgepodcast/ --- Today's sources: Dutton, D. G., & Aron, A. P. (1974). Some evidence for heightened sexual attraction under conditions of high anxiety. Journal of Personality and Social Psychology, 30(4), 510–517. Graves, P. (2010). Consumer.ology: The market research myth, the truth about consumers and the psychology of shopping. Nicholas Brealey. Hasel, L.E. & Kassin, S.M. (2009). On the presumption of evidentiary independence: Can confessions corrupt eyewitness identifications? Psychological Science, 20(1), 122. McClure, S. M., Li, J., Tomlin, D., Cypert, K. S., Montague, L. M., & Montague, P. R. (2004). Neural correlates of behavioral preference for culturally familiar drinks. Neuron, 44(2), 379–387. Nisbett, R. E., & Wilson, T. D. (1977). Telling more than we can know: Verbal reports on mental processes. Psychological Review, 84(3), 231–259.
University of South Carolinaで独立した小川優樹さん(@YukiOgawaPhD)ゲスト回。AISに興味を持つようになるまでの過程、ポスドクを行ったBaylor Collegeでの研究、ジョブハント体験記、最新作Hide-and-seekに関するディスカッション、今後の展望について (2/22 収録)Show Notes (番組HP):小川さんラボHP岡野ジェイムス洋尚ラボ(再生医学研究室)Matthew Rasband lab星でやっていた薬物依存の研究岡野ジェイムス洋尚先生慶應の岡野栄之先生パーキンソン病患者の脳内に胎児からの幹細胞を打って改善?薬物依存における神経変性: 1 2岡野ジェイムス洋尚先生が昔からやっていた研究の例院でやっていたHuCの研究 (院での研究その1, KIFの内容は論文に出してました by 小)Robert Darnell labHITS-CLIPKIFレビューAnkyrin Gがなくなると軸索がなくなる (より正確には、「軸索が樹状突起っぽくなる」でした by 小)Neuronの突起はデフォルトが樹状突起になっているようで、軸索へのspecificationにAnkyrinGが関わっています by 小小脳だとHuCが多いのtable2胎児期と大人で変わってくる (院での研究その2)軸索にはDNAがないミトコンドリアが集積する、のプレプリントAxon carrying dendriteの報告論文とリップル参加率の違いPaclitaxelを培養ニューロンに処理すると軸索が増える:1 2以前に留学していた吉村武先生International Society of Neurochemistry (日本神経化学会の国際学会)の合宿、advanced school神経化学会の雑誌で記事を書いています by 小山本先生ラボ (その後ゲストとして登場して先に公開されてます)MD Anderson Cancer CenterAISのタンパク質をBioID法で網羅的に解析した論文BioID法、元論文UCLAでの共同研究先:UCSFでした、間違えました(泣) by 小Adelson FoundationsMattラボで最初に出したRanbp2論文抗体のクオリティ問題に関するエッセイAAV crude prepのAllenのプロトコルHide-and-Seek論文ではHEKを凍結融解しない方法を採用しています。細胞を壊さないためToxicな成分が少ないのかなと思ってはいますが比較したことはないです。 by 小HiUGE法 (HDR非依存ノックイン)Mattラボでのメインワーク 日本語の記事SLENDR (HDR依存ノックイン)vSLENDR (HDR依存ノックイン)HITI (HDR非依存ノックイン)Split Cas9smFPスパゲッティ・モンスター教宮脇敦史先生の蛍光タンパク質の本TurboIDUltraID日本で開発されたAirIDは直接相互作用しているタンパクの同定に適しているそうです論文中で使った抗体依存的なビオチン化 1 2 3同時期に出た、permeabilitzation後にラベルした論文 (共同研究その1)Split TurboID高野さん高野さんの三者間シナプスでのSplit-TurboIDSubhojit Roy共同研究その2共同研究その3五十嵐先生井上さんご夫妻Outlookでエキスポートする方法Carolina Autism and Neurodevelopment (CAN) Research CenterUniversity of South CarolinaのDepartment of Biological SciencesThe Medical University of South CarolinaHide-and-Seekのプレプリント(が論文になったもの)Gephyrinはどこまで重要か、の議論Taniguchiさんのシャンデリア論文MADMCiliaセロトニンレセプターが良く出ている池谷研からBLA axo-axonic cell のgenetic labelingIntersectional な方法でのaxo-axonic cell labeling興奮性に働くAxo-axonic synapsedevelopment中のGABAは興奮性大学側がNIHを書くなと言ってくる例Zillow (普通留学中はアパートを借りると思いますが、一軒家を借りようとしたので手間取りました。アパートなら普通に借りれたと思います。前ボスからは「5年以上住むなら家を買うのはあり」と言われました。 by 小)羊土社の留学本近接依存性標識プロトコルの本分生でのシンポジウムこの度は呼んで頂きありがとうございました!ジョブハントは業績も大事ですがマッチングも大事です。論文がトップジャーナルに載らなくても採用のチャンスは十分にあると感じました。またこのラジオで神経分子研究の面白さが少しでも伝わっていれば嬉しいです。研究内容などに興味・ご相談のある方はお気軽にご連絡ください (小川)使ったことはないものの学びたかった手法が盛りだくさんだったので役得感ありました(萩原) 追記:公開までに半年空いた(revisionお疲れ様でした)ので聴き直してみましたが、全然内容覚えてなかったので再び学びがありました。使用しているメソッドの特徴が「これを解析するために作られた!」というくらい興味対象にピッタリとハマっているのが印象的でした (脇)
In this hands-on episode, Corey and Grant attempt to build three different AI apps in one hour using Google AI Studio - with zero coding experience required. They create an Inbox Zero email organizer, a meme generator that roasts their photos, and a spontaneous adventure planner with interactive maps. Watch as they navigate errors, discover workarounds, and prove that anyone can build functional AI apps without being a developer.Subscribe to The Neuron newsletter: https://theneuron.aiOriginal article: https://www.theneuron.ai/newsletter/googles-ai-makes-you-appsRead more: https://www.theneuron.ai/explainer-articles/how-to-build-an-ai-agent-part-one-testing-googles-firebase-studio-ai-agent-builderGoogle AI Studio: https://aistudio.google.comNoCodeMBA Tutorial: https://youtu.be/ANth52yyr9U?si=L9iT1-eYgB8nOfrgAlternative builders mentioned:- Lovable: https://lovable.dev- Claude Artifacts: https://claude.ai- V0 by Vercel: https://v0.dev- Bolt.new: https://bolt.new
OpenAI just dropped ChatGPT Agent, and we test it LIVE for the first time. Watch as we put this "true" AI agent through its paces - from finding the perfect Gibson Les Paul to building competitive intelligence reports. We explore what makes this different from Zapier-style automation, demonstrate real-world use cases, and discuss why this might be the beginning of America's first super app. Plus: can it actually convince Corey's wife he needs a new guitar?Subscribe to The Neuron newsletter: https://theneuron.aiOriginal article: https://www.theneuron.ai/newsletter/openais-new-agent-is-hereRead More: https://www.theneuron.ai/explainer-articles/how-to-build-your-own-ai-agent-without-being-a-pro-coderhttps://www.theneuron.ai/newsletter/operator-book-me-some-clientsChatGPT Agent: https://openai.com/index/introducing-chatgpt-agent/ N8N: https://n8n.io/
留言告訴我你對這一集的想法: https://open.firstory.me/user/ckq9bl3vd660p0805d1apvgrd/commentsBook a free consultation: https://calendly.com/d/zzg-xx9-gjdMandarin Lessons: https://yunfei.world/languages/learn-mandarin/Email: zhuimin9698@gmail.comIG@ huimin_taiwan_mandarin· Paypal: PayPal.Me/ZhanghuiminTW · Transcript: patreon.com/user?u=66323162 生詞表 vocabulary list 編號 中文 拼音 英文 1. 壽命 shòu mìng Lifespan 2. 稀奇 xī qí Rare/unusual 3. 科學發達 kē xué fā dá Scientific advancement 4. 六十大壽 liù shí dà shòu 60th birthday celebration 5. 生命 shēng mìng Life 6. 天花板 tiān huā bǎn Ceiling 7. 死亡的來臨 sǐ wáng de lái lín The arrival of death 8. 臥床 wò chuáng Bedridden 9. 輪迴轉世 lún huí zhuǎn shì Reincarnation 10. 遊樂園 yóu lè yuán Amusement park 11. 退休年齡 tuì xiū nián líng Retirement age 12. 平均壽命 píng jūn shòu mìng Average lifespan 13. 人瑞 rén ruì Centenarian 14. 歷史新高紀錄 lì shǐ xīn gāo jì lù Record high in history 15. 高齡人口 gāo líng rén kǒu Elderly population 16. 超高齡社會 chāo gāo líng shè huì Super-aged society 17. 高齡化社會 gāo líng huà shè huì Aging society 18. 高齡社會 gāo líng shè huì Aged society 19. 超過 chāo guò Exceed/surpass 20. 認真思考 rèn zhēn sī kǎo Think seriously 21. 合法 hé fǎ Legal 22. 自願退休 zì yuàn tuì xiū Voluntary retirement 23. 制定 zhì dìng Formulate/establish 24. 醫藥發達 yī yào fā dá Medical advancement 25. 癌症 ái zhèng Cancer 26. 治好 zhì hǎo Cured 27. 完全治癒 wán quán zhì yù Complete recovery 28. 往後延 wǎng hòu yán Postpone/delay 29. 延後 yán hòu Delay/postpone 30. 挑戰 tiǎo zhàn Challenge 31. 足夠的錢 zú gòu de qián Enough money 32. 財富自由 cái fù zì yóu Financial freedom 33. 維持健康狀態 wéi chí jiàn kāng zhuàng tài Maintain healthy condition 34. 老化 lǎo huà Aging 35. 必然的過程 bì rán de guò chéng Inevitable process 36. 受傷 shòu shāng Get injured 37. 跌倒 diē dǎo Fall down 38. 惡性循環 è xìng xún huán Vicious cycle 39. 肌少症 jī shǎo zhèng Sarcopenia 40. 重量訓練 zhòng liàng xùn liàn Weight training 41. 舉重 jǔ zhòng Weightlifting 42. 骨頭密度 gǔ tóu mì dù Bone density 43. 減少 jiǎn shǎo Decrease/reduce 44. 骨折 gǔ zhé Bone fracture 45. 肌肉 jī ròu Muscle 46. 骨頭 gǔ tóu Bone 47. 刺激 cì jī Stimulate 48. 靈活 líng huó Flexible/agile 49. 細胞 xì bāo Cell 50. 活化 huó huà Activate 51. 腦力退化 nǎo lì Mental capacity 52. 記憶 jì yì Memory 53. 退化 tuì huà Degenerate/deteriorate 54. 社交生活 shè jiāo shēng huó Social life 55. 互動 hù dòng Interact 56. 啟動大腦 qǐ dòng dà nǎo Activate the brain 57. 獨處 dú chǔ Solitude/being alone 58. 活躍 huó yuè Active 59. 長壽 cháng shòu Longevity 60. 學習新事物 xué xí xīn shì wù Learn new things 61. 思考 sī kǎo Think 62. 神經元 shén jīng yuán Neuron 63. 產生新的連結 chǎn shēng xīn de lián jié Create new connections 64. 彈奏樂器 tán zòu yuè qì Play musical instruments 65. 視覺 shì jué Vision 66. 看譜 kàn pǔ Read sheet music 67. 聽覺 tīng jué Hearing 68. 音符 yīn fú Musical note 69. 促進情緒發展 cù jìn qíng xù fā zhǎn Foster emotional development 70. 抒情音樂 shū qíng Ballad music 71. 舒緩情緒 shū huǎn qíng xù Relieve emotions 72. 得到安慰 dé dào ān wèi Get comfort 73. 調節情緒 tiáo jié qíng xù Regulate emotions 74. 避免久坐 bì miǎn jiǔ zuò Avoid sitting for a long time 75. 血液循環 xuè yè xún huán Blood circulation 76. 中風 zhòng fēng Stroke 77. 心臟病 xīn zàng bìng Heart disease 78. 風險 fēng xiǎn Risk 79. 加速老化 jiā sù lǎo huà Accelerate aging 80. 靜態活動 jìng tài huó dòng Sedentary activity 81. 手工藝品 shǒu gōng yì pǐn Handicrafts 82. 付房貸 fù fáng dài Pay mortgage 83. 對別人有貢獻 duì bié rén yǒu gòng xiàn Contribute to others 84. 總結一下 zǒng jié yī xià To summarize Powered by Firstory Hosting
Support the show to get full episodes, full archive, and join the Discord community. The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists. Read more about our partnership. Sign up for Brain Inspired email alerts to be notified every time a new Brain Inspired episode is released. To explore more neuroscience news and perspectives, visit thetransmitter.org. A few episodes ago, episode 212, I conversed with John Beggs about how criticality might be an important dynamic regime of brain function to optimize our cognition and behavior. Today we continue and extend that exploration with a few other folks in the criticality world. Woodrow Shew is a professor and runs the Shew Lab at the University of Arkansas. Keith Hengen is an associate professor and runs the Hengen Lab at Washington University in St. Louis Missouri. Together, they are Hengen and Shew on a recent review paper in Neuron, titled Is criticality a unified setpoint of brain function? In the review they argue that criticality is a kind of homeostatic goal of neural activity, describing multiple properties and signatures of criticality, they discuss multiple testable predictions of their thesis, and they address the historical and current controversies surrounding criticality in the brain, surveying what Woody thinks is all the past studies on criticality, which is over 300. And they offer a account of why many of these past studies did not find criticality, but looking through a modern lens they most likely would. We discuss some of the topics in their paper, but we also dance around their current thoughts about things like the nature and implications of being nearer and farther from critical dynamics, the relation between criticality and neural manifolds, and a lot more. You get to experience Woody and Keith thinking in real time about these things, which I hope you appreciate. Shew Lab. Hengen Lab. Is criticality a unified setpoint of brain function? 0:00 - Intro 3:41 - Collaborating 6:22 - Criticality community 14:47 - Tasks vs. Naturalistic 20:50 - Nature of criticality 25:47 - Deviating from criticality 33:45 - Sleep for criticality 38:41 - Neuromodulation for criticality 40:45 - Criticality Definition part 1: scale invariance 43:14 - Criticality Definition part 2: At a boundary 51:56 - New method to assess criticality 56:12 - Types of criticality 1:02:23 - Value of criticality versus other metrics 1:15:21 - Manifolds and criticality 1:26:06 - Current challenges
Headlines scream that AI is "breaking the classroom," but is the story that simple? In this episode we explore the real cracks in today's education system, how AI sometimes widens them, and—more importantly—how the same technology could personalize learning, free teachers to teach, and shift schools from rote memorization to true mastery. We discuss the UCLA "CheatGPT" controversy, MIT's brain study, Alpha School's 2-hour learning model, and OpenAI's new $10M teacher training initiative.Subscribe to The Neuron newsletter: https://theneuron.aiWTF is going on with AI and education: https://www.theneuron.ai/explainer-articles/wtf-is-going-on-with-ai-and-educationOne Useful Thing (Ethan Mollick) Post-apocalyptic education: https://www.oneusefulthing.org/p/post-apocalyptic-education MIT study: https://www.media.mit.edu/publications/your-brain-on-chatgpt/ Ethan Mollick again, “Against brain damage”: https://www.oneusefulthing.org/p/against-brain-damage OpenAI working with teachers union: https://openai.com/global-affairs/aft/ Make it Stick book: https://www.makeitstick.com/
Sabine VdL talks to Lou Smith, a true trailblazer in the world of financial services and insurance. In today's episode, we'll dive into Lou's incredible journey, explore the vision behind Neuron, and discuss the key takeaways from the latest report that insurance providers need to consider. KEY TAKEAWAYS We all have moments in life where the last thing we want to look at is out credit rating and history, but those things can affect how you access financial services in the future. Lou was part of the team that delivered the first end-to-end mortgage renewal online, started to break down investments and getting it to the hands of the many rather than the few. Everybody says insurance is behind the rest of the financial services industry, and it's a funny statement. It doesn't matter. What I'm seeing in insurance in the last 5-6 years is that this conversation has circled around about what do we do? But in the last 12-18 months I've seen a passion for how do now think about using digital, distribution models, digital, analytics and AI and thinking of all of those things together and deliver distribution models that start to move industry forward. The challenge is always in leadership, culture and change adoption. This is because it's really difficult to step into an unknown and think it's going to be better than what you're doing today. You want to power people with the data and capabilities so they can do what they're brilliant at, which is focusing on the best product and position for their client. Neuron and others enable brokers to do that. You also want to attract a new generation into the brokering sector, but rather than have them focus on the admin of that sector, they should be having great conversations with clients. All the work we're doing enables brokers to do that. BEST MOMENTS ‘When starting my career I had a real passion for how to make the services we were offering more successful for clients and customers.'‘We care about the customer and making financial data accessible to you through the narratives we use.'‘I'd love to say this was all planned out, we didn't call it anything or know what it looked like, we just started to bring data and technologies together to build ‘workflow' and that's now become cool.'‘We want to be the easiest, most predictable and consistent broker to work with.' ABOUT THE GUEST Louise (or Lou) Smith is a trailblazer in the financial services and insurance industries, with a career spanning leadership roles across digital transformation, data, product innovation, distribution, technology, and operations. Her journey has been marked by groundbreaking achievements, including delivering the UK's first steps into digital distribution at Barclays, leading the digital transformation of the Royal Bank of Scotland (including NatWest) during its turnaround to profitability, and becoming the first-ever Chief Digital Officer at Lloyd's of London. Currently, Louise is at the helm of Neuron, a transformative initiative aimed at redefining the insurance and financial services landscape. Through Neuron, she is driving innovation, collaboration, and growth, focusing on creating a more connected and customer-centric industry. WTWCO LinkedIn ABOUT THE HOST Sabine is a corporate strategist turned entrepreneur. She is the CEO and Managing Partner of Alchemy Crew a venture lab that accelerates the curation, validation, & commercialization of new tech business models. Sabine is renowned within the insurance sector for building some of the most renowned tech startup accelerators around the world working with over 30 corporate insurers, accelerated over 100 startup ventures. Sabine is the co-editor of the bestseller The INSURTECH Book, a top 50 Women in Tech, a FinTech and InsurTech Influencer, an investor & multi-award winner. Twitter LinkedIn Instagram Facebook TikTok Email Website This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/
India is witnessing a transformation in urban mobility underpinned by a growing ecosystem of cleantech solutions. Neuron Energy is a key player in this space, focused on building full-stack energy systems for the electric future. On a mission to innovate scalable solutions, Neuron Energy's co-founder Pratik Kamdar joins us on this episode of Unusual Suspects to chart the course of electric mobility in India and the world. He sheds light on the startup's experimentation with next-generation battery technologies, such as sodium-ion, which could open new possibilities, marking a pivotal chapter in the unfolding story of electric energy storage systems.
The MidPacker Pod is part of the Freetrail network of Podcasts.Join the Newsletter at: MidPack Musings SubStackSupport the MidPacker Pod on Patreon.Check Out MPP Merch Make sure you leave us a rating and review wherever you get your pods.Looking for 1:1 Ultra Running Coaching? Check out Troy's Coaching PageSTOKED TO PARTNER WITH JANJI HYPERLYTE LIQUID PERFORMANCEBEAR BUTT WIPES USE PROMO CODE MIDPACER FOR A SWEET DISCOUNT“Endurance running taught me that suffering can be healing.”On this episode of the MidPacker Pod, host Troy Meadows sits down with someone whose name you might recognize from the tech world—but whose story on the trails is just as compelling. Randi Zuckerberg joins Troy to talk about grit, glitter, and the deeply personal journey that's taken her from postpartum struggles to finishing Cocodona 250. This isn't just a tale of logging miles—it's about reclaiming identity, building resilience, and weaving together family, career, and ultrarunning in the most authentic way.“This is mine—my grit, my journey,” she told herself. From there, running became more than just fitness—it became therapy, transformation, and a bold new identity.Randi has built her ultrarunning life around presence, creativity, and deep connection.She trains early—usually 4 to 7 a.m.—before her family wakes.Her kids are part of the experience, running their own races at events.Her husband is training for an Ironman.Her 5-year-old daughter completed a 1K trail race.She embraces what she calls a “well-lopsided” balance—going all-in on what matters most in each moment.Always a builder at heart, Randi's bringing her entrepreneurial energy into the endurance world:She's an angel investor and advisor in several trail and ultra-related startups.Current investments include:Janji - (friend of the pod)Neuron (AI-powered pacing app)RUNNA (training and coaching platform)Through these projects, she's helping create tools and communities that support and elevate everyday runners—just like us.Randi's Links: IG - @randizuckerbergRadio Show - Randi Zuckerberg Means Business on SiriusXMPartner Links: Janji - Janji.comA big shoutout to our sponsor, Janji! Their running apparel is designed for everyday exploration, and 2% of sales support clean water initiatives worldwide. Plus, with a five-year guarantee, you know it's gear you can trust. Check them out at janji.com,Use the code MIDPACKER for 10% off your order.Hyerlyte Liquid Performance - https://www.hyperlyteliquidperformance.comMade by the ultra-endurance athlete, for the ultra-endurance athlete.H001 is a new hydration mix that has the carbs and sodium your body needs for high-output adventures in a single serving.Check them out at hyperlyteliquidperformance.comUse the code MIDPACKER for 10% off your individual order and 10% off your first subscription order.Bear Butt Wipes - Bearbuttwipes.comPortable individually wrapped wipes for when nature calls and a DNF is not an option. Bear Butt Wipes: Stay wild. Stay clean.Check them out at Bearbuttwipes.comUse the code MIDPACKER for 10% off your order.Run Trail Life - https://runtraillife.com/Find Official MPP Merch on RTL!!Use code: midpackerpod to double the donation from your purchase. Visit RunTrailLife.com to check out our line of Hats and Organic cotton T's.Freetrail - https://freetrail.com/Visit Freetrail.com to sign up today.Randi Zuckerberg, Cocodona 250, postpartum depression, ultrarunning, family running, tech and endurance, Neuron pacing app, UltraSignup, RUNNA, Janji, women in endurance, OrangeTheory, trail running, mental resilience, sleep deprivation, endurance mindset, Tahoe Rim Trail, Black Canyon Ultras, NYC Marathon, ultra crew dynamics, grit, transformation, Freetrail, MidPacker Pod
Listen as Michael S. Blaiss, MD provides case-based perspectives on chronic cough recognition, burden, management, and pathophysiology and describes the evolving treatment landscape for refractory chronic cough.PresenterMichael S. Blaiss, MDClinical Professor of PediatricsDivision of Allergy-ImmunologyMedical College of Georgia at Augusta UniversityAugusta, GeorgiaLink to full program: https://bit.ly/4kweynG
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When panic strikes, it hits before thought has a chance to catch up. In this episode, I get real about fear — not the idea of it, but the full-body experience. We'll talk about how panic hijacks the brain, how to self-soothe, and what I learned on the trail when things got intense. A grounded, honest look at fear, and how to walk through it. Quote of the Week:“You gain strength, courage, and confidence by every experience in which you really stop to look fear in the face.” – Eleanor RooseveltReferences:Whalen, P. J., et al. (2001). Human amygdala responsivity to masked fearful eye whites. Neuron, 27(3), 595–601.Schiller, D., et al. (2010). Preventing the return of fear in humans using reconsolidation update mechanisms. Nature, 463(7277), 49–53.Let's go, let's get it done. Get more information at: http://projectweightloss.org
In just 27 minutes, you can learn 7 scientifically backed marketing tactics to apply to your website today. You'll learn: How one word increased my email open rate by 6.4%. The tiny reward that helped a cafe generate 1,276 5-star reviews. Why adding steps increased job applicants by 20%. How “you'll lose X” reduced customer cancellations by 90%. The irrelevant reason that boosted conversions by 41%. And the irrational addition that increased conversions by 2x. --- Sign up for the Bas's community Online Influence: https://shorturl.at/vNYOU My social proof a/b test results: https://ibb.co/mCsdwFVb Kia Ora Cafe surprise reward: https://shorturl.at/YdG4q Bas's book Online Influence: https://www.onlineinfluence.com/book-online-influence/ Subscribe to the (free) Nudge Newsletter: https://nudge.ck.page/profile Connect on LinkedIn: https://www.linkedin.com/in/phill-agnew-22213187/ Watch Nudge on YouTube: https://www.youtube.com/@nudgepodcast/ --- Sources: Berridge KC, Kringelbach ML (2015). Pleasure systems in the brain. Neuron 6;86(3):646-64. Behavioural Insights Team. (2014). EAST: Four simple ways to apply behavioural insights. Behavioural Insights Ltd. Gonzales MH, Aronson E, Costanzo M (1988). Increasing the effectiveness of energy auditors: a field experiment. Journal of Applied Social Psychology 18:1046-66. Langer, E. J., Blank, A., & Chanowitz, B. (1978). The mindlessness of ostensibly thoughtful action: The role of "placebic" information in interpersonal interaction. Journal of Personality and Social Psychology, 36(6), 635–642. https://doi.org/10.1037/0022-3514.36.6.635 Grieser S (2014). Is too much choice killing your conversion rates? [Case studies] Unbounce. Via: www.unbounce.com/conversion-rate-optimization/psychology-of-choice-conversion-rates
This week on the show: Are we ready to create digital models of the human brain? Last month, Stanford researcher Andreas Tolias and colleagues created a "digital twin" of the mouse visual cortex. The researchers used the same foundation model approach that powers ChatGPT, but instead of training the model on text, the team trained in on brain activity recorded while mice watched action movies. The result? A digital model that can predict how neurons would respond to entirely new visual inputs. This landmark study is a preview of the unprecedented research possibilities made possible by foundation models of the brain—models which replicate the fundamental algorithms of brain activity, but can be studied with complete control and replicated across hundreds of laboratories.But it raises a profound question: Are we ready to create digital models of the human brain? This week we talk with Wu Tsai Neuro Faculty Scholar Dan Yamins, who has been exploring just this question with a broad range of Stanford colleagues and collaborators. We talk about what such human brain simulations might look like, how they would work, and what they might teach us about the fundamental algorithms of perception and cognition.Learn moreAI models of the brain could serve as 'digital twins' in research (Stanford Medicine, 2025)An Advance in Brain Research That Was Once Considered Impossible (New York Times, 2025)The co-evolution of neuroscience and AI (Wu Tsai Neuro, 2024)Neuroscientists use AI to simulate how the brain makes sense of the visual world (Wu Tsai Neuro, 2024)How Artificial Neural Networks Help Us Understand Neural Networks in the Human Brain (Stanford Institute for Human-Centered AI (HAI), 2021)Related researchA Task-Optimized Neural Network Replicates Human Auditory Behavior... (PNAS, 2014)Vector-based navigation using grid-like representations in artificial agents (Nature, 2018)The neural architecture of language: Integrative modeling converges on predictive processing (PNAS, 2021)Using deep reinforcement learning to reveal how the brain encodes abstract state-space representations... (Neuron, 2021) We want to hear from your neurons! Email us at at neuronspodcast@stanford.edu. Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.
Satelit ROSE-L díky největší anténě svého druhu pomůže lépe sledovat změnu klimatu, blížící se zemětřesení anebo pomůže navigaci lodí. Jak? Česko-slovenský tým vědců - archeologů objevuje v guatemalské džungli další a další mayské památky. Děje se tak díky lidaru - leteckému laserovému scanování, které umožňuje objevit pevné ruiny staveb a soch i v těžko propustné džungli. Expedici Abuelos a její mimořádné objevy podpořila nadace Neuron. - Na Mezinárodní vesmírné stanici budou měřit čas a to i díky detektoru českých vědců. Proč je tak důležité vědět, kolik hodin přesně mají ve vesmíru?
Numerous neuron models have been made, but most of them are "single-purpose" in that they are made to address a single scientific question. In contrast, multipurpose neuron models are made to be used to address many scientific questions. In 2011, the guest published a multipurpose rodent pyramidal-cell model which has been actively used by the community ever since. We talk about how such models are made, and how his group later built human neuron models to explore network dynamics in brains of depressed patients.
Two-thirds of those diagnosed with Alzheimer's disease are women — but why? In this episode, we unpack the neurological, hormonal, and social drivers that uniquely affect women's brain health during the menopausal transition — from estrogen's protective role in the brain to the misunderstood history of hormone replacement therapy. We discuss: • Why women face a higher risk of Alzheimer's than men • How menopause accelerates brain aging (and how it starts earlier than is often expected) • The role of estrogen in brain metabolism and neuroprotection • The real story behind hormone replacement therapy (HRT) • The impact of genes like APOE4 on women's brain health • How lifestyle factors like stress, sleep, and cognitive activity can help reduce the impact of neurological changes onset by menopause ——— Get our free curation of women's brain health resources in our Brain Box: http://thebraindocs.com/brainbox ——— To help us tell this story, we welcome three world-renowned women's health experts to the podcast: DR. LISA MOSCONI: Director of the Women's Brain Initiative, author of ‘The Menopause Brain', and pioneering researcher in brain imaging and hormonal neuroscience. MARIA SHRIVER: Founder of the Women's Alzheimer's Movement, journalist, and relentless advocate for gender equity in brain health research. DR. LISA GENOVA: Neuroscientist and bestselling author of ‘Still Alice', which was adapted into a film starring Julianne Moore, who won the 2015 Best Actress Oscar for her role as Alice Howland. This is... Your Brain On Menopause. ‘Your Brain On' is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Menopause' • SEASON 5 • EPISODE 1 ——— Our free Women's Brain Health Brain Box includes: • Guides on how to speak with healthcare providers about menopause • Delicious brain-healthy Mother's Day brunch recipes • Meaningful gift ideas for the women you love • Inspiring interviews with world-leading women's health experts • And even a chance to check your cognitive health with an insightful, science-backed test Get the Brain Box for free! Here: http://thebraindocs.com/brainbox ——— References: Mosconi, L. (2017). Perimenopause and emergence of an Alzheimer's bioenergetic phenotype in brain and periphery. PloS One, 12(10), e0185926. Belloy, M. E. & Alzheimer's Disease Neuroimaging Initiative. (2019). A quarter century of APOE and Alzheimer's disease: Progress to date and the path forward. Neuron, 101(5), 820-838. Rahman, A. (2019). Sex and gender driven modifiers of Alzheimer's: The role for estrogenic control across age, race, medical, and lifestyle risks. Frontiers in Aging Neuroscience, 11, 315. Rocca, W. A. (2012). Hysterectomy, oophorectomy, estrogen, and the risk of dementia. Neurodegenerative Diseases, 10(1-4), 175-178. Scheyer, O. (2018). Female sex and Alzheimer's risk: The menopause connection. Journal of Prevention of Alzheimer's Disease, 5(4), 225-230. Women's Health Initiative Memory Study Investigators. (2003). Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: The Women's Health Initiative Memory Study—a randomized controlled trial. JAMA, 289(20), 2651–2662. Women's Health Initiative Investigators. (2002). Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial. JAMA, 288(3), 321-333. Whitmer, R. A. (2005). Midlife cardiovascular risk factors and risk of dementia in late life. Neurology, 64(2), 277-281. Livingston, G. (2024). Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. The Lancet, 404(10452), 572-628. Maki, P. M. (2016). Hormone therapy, dementia, and cognition: The Women's Health Initiative 10 years on. Climacteric, 19(3), 313-315.
Send us a textThis week we look to deunk myths about rising autism rates and explain the genetic and environmental factors at play, while exploring the resurrection of dire wolves through genetic engineering and how puppy cognition predicts adult dog behavior.• CDC data shows autism diagnoses increased from 1 in 150 children in 2000 to 1 in 31 in 2022• Approximately 80% of autism cases stem from inherited genetic variations with 200+ genes linked to early brain development• Better screening, diagnosis, and awareness accounts for much of the increase in autism rates• Scientists have genetically engineered puppies with dire wolf traits using DNA from ancient remains• The three pups—Romulus, Remus, and Khaleesi—received 20 gene edits targeting coat color, body size, and facial features• Study of 1,400+ puppies shows early cognitive traits persist into adulthood• Puppies good at following pointing gestures became more trainable adults, while those with better impulse control grew into calmer dogs• Understanding puppy cognition allows for customized training approaches that support lifelong well-beingSome Links and Studies:https://www.sciencenews.org/article/autism-adhd-risk-not-linked-prenatal-exposure-antidepressantsS. Gilman et al. Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron, Vol. 70, June 9, 2011. DOI:10.1016/j.neuron.2011.05.021D. Levy et al. Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders. Neuron, Vol. 70, June 9, 2011. DOI 10.1016/j.neuron.2011.05.015Y. Sakai et al. Protein interactome reveals converging molecular pathways among autism disorders. Science Translational Medicine, Vol. 3, June 8, 2011. doi: 10.1126/scitranslmed.3002166Sanders et al. Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism. Neuron, Vol. 70, June 9, 2011. DOI:10.1016/j.neuron.2011.05.015C. Schaaf et al. Oligogenic heterozygosity in individuals with high-functioning autism spectrum disorder. Human Molecular Genetics. doi: 10.1093/hmg/ddr243. Available online: [Go to]C.P. Schaaf and H.Y. Zoghbi. Solving the autism puzzle a few pieces at a time. Neuron, Vol. 70, June 9, 2011. DOI: 10.1016/j.neuron.2011.05.025I. Voineagu et al. Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature. doi: doi:10.1038/nature10110Our links:Our Website! www.bunsenbernerbmd.comSign up for our Weekly Newsletter!Bunsen and Beaker on Twitter:Bunsen and Beaker on TikTokSupport the showFor Science, Empathy, and Cuteness!Being Kind is a Superpower.https://twitter.com/bunsenbernerbmd
Support the show to get full episodes, full archive, and join the Discord community. Gabriele Scheler co-founded the Carl Correns Foundation for Mathematical Biology. Carl Correns was her great grandfather, one of the early pioneers in genetics. Gabriele is a computational neuroscientist, whose goal is to build models of cellular computation, and much of her focus is on neurons. We discuss her theoretical work building a new kind of single neuron model. She, like Dmitri Chklovskii a few episodes ago, believes we've been stuck with essentially the same family of models for a neuron for a long time, despite minor variations on those models. The model Gabriele is working on, for example, respects the computations going on not only externally, via spiking, which has been the only game in town forever, but also the computations going on within the cell itself. Gabriele is in line with previous guests like Randy Gallistel, David Glanzman, and Hessam Akhlaghpour, who argue that we need to pay attention to how neurons are computing various things internally and how that affects our cognition. Gabriele also believes the new neuron model she's developing will improve AI, drastically simplifying the models by providing them with smarter neurons, essentially. We also discuss the importance of neuromodulation, her interest in wanting to understand how we think via our internal verbal monologue, her lifelong interest in language in general, what she thinks about LLMs, why she decided to start her own foundation to fund her science, what that experience has been like so far. Gabriele has been working on these topics for many years, and as you'll hear in a moment, she was there when computational neuroscience was just starting to pop up in a few places, when it was a nascent field, unlike its current ubiquity in neuroscience. Gabriele's website. Carl Correns Foundation for Mathematical Biology. Neuro-AI spinoff Related papers Sketch of a novel approach to a neural model. Localist neural plasticity identified by mutual information. Related episodes BI 199 Hessam Akhlaghpour: Natural Universal Computation BI 172 David Glanzman: Memory All The Way Down BI 126 Randy Gallistel: Where Is the Engram? 0:00 - Intro 4:41 - Gabriele's early interests in verbal thinking 14:14 - What is thinking? 24:04 - Starting one's own foundation 58:18 - Building a new single neuron model 1:19:25 - The right level of abstraction 1:25:00 - How a new neuron would change AI
As this work begins to bear fruit, researchers “are becoming less afraid to ask very difficult questions that you can uniquely ask in people.”
Intelligence seems to correlate with total number of neurons in the brain. Different animals' intelligence levels track the number of neurons in their cerebral cortices (cerebellum etc don't count). Neuron number predicts animal intelligence better than most other variables like brain size, brain size divided by body size, “encephalization quotient”, etc. This is most obvious in certain bird species that have tiny brains full of tiny neurons and are very smart (eg crows, parrots). Humans with bigger brains have on average higher IQ. AFAIK nobody has done the obvious next step and seen whether people with higher IQ have more neurons. This could be because the neuron-counting process involves dissolving the brain into a “soup”, and maybe this is too mad-science-y for the fun-hating spoilsports who run IRBs. But common sense suggests bigger brains increase IQ because they have more neurons in humans too. Finally, AIs with more neurons (sometimes described as the related quantity “more parameters”) seem common-sensically smarter and perform better on benchmarks. This is part of what people mean by “scaling”, ie the reason GoogBookZon is spending $500 billion building a data center the size of the moon. All of this suggests that intelligence heavily depends on number of neurons, and most scientists think something like this is true. But how can this be? https://www.astralcodexten.com/p/why-should-intelligence-be-related
TWiN explains a study showing that when a mouse is confronted with an unconscious conspecific, it engages in behavior including tongue-dragging to resuscitate the animal via a tongue-brain connection. Hosts: Vincent Racaniello, Tim Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Tongue-dragging in mice (Sci Adv) Timestamps by Jolene Ramsey. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv
This study by Vaneet Kaur introduces a novel framework that integrates social neuroscience and entrepreneurship to explore how neuronal pathways enable the transformation of individuals into entrepreneurs with robust capabilities. Moving beyond traditional individual-centric views, it investigates inter-individual neural and social synchronization, identifying neurosocial mediators that drive the development of entrepreneurial competencies within enterprises. By leveraging the extended mirror neuron system and neuroplasticity, this conceptual paper demonstrates how social learning processes activate and strengthen neural networks, resulting in emergent entrepreneurial behaviors. Employing a theory-bridging approach, this research develops a nomological network to predict relationships between entrepreneurial and neurosocial constructs, clarifying causal linkages, antecedents, outcomes, and contingencies. This framework offers a comprehensive understanding of how individual capabilities evolve into entrepreneurial capabilities, moving beyond assumptions of serendipity and simplistic aggregation.
Osteosarcoma Webinar Series: Sowmya Ramesh, PhD joins us on OsteoBites to discuss how multi-modal omics analysis identifies targetable sensory neuron circuitry that promotes sarcoma disease progression.Bone pain is a hallmark of bone cancers, including osteosarcoma (OS), mediated by skeletal-innervating peripheral afferent neurons. However, the roles of tumor-associated sensory neurons in OS beyond pain perception remain poorly understood. To investigate their regulatory functions, a chemical-genetic approach was employed in mice carrying a knock-in allele for TrkA to perturb sensory nerve innervation during OS growth and progression. TrkA inhibition in these transgenic mice significantly reduced sarcoma-associated sensory innervation and vascularization, altered tumor-associated macrophage polarization, decreased tumor growth and metastasis, and extended overall survival.These findings suggest that targeting pathological innervation in OS may serve as an adjunctive therapy to enhance clinical outcomes and survival.Dr. Ramesh is a postdoctoral researcher from the James lab at Johns Hopkins. The lab's research focus lies at the intersection of skeletal pathophysiology and stem cell biology. The lab looks at the interaction of nerves in various musculoskeletal repair including bone repair and regeneration, osteoprogenitor cell characterization, and neoplastic bone. Dr. Ramesh specifically works on understanding how peripheral nerves regulate osteosarcoma disease progression.
This episode of Naked Neuroscience is co-published on the Naked Scientists Podcast. James Tytko examines one of the largest causes of disability amongst the young: multiple sclerosis. We hear from Lara Kingsman who is living with MS, doctors at the University of Cambridge take us inside the brain to help guide interventions, and the MS Society tell us about their innovative drug trial in collaboration with UCL to help find new treatments... Like this podcast? Please help us by supporting the Naked Scientists
Support the show to get full episodes, full archive, and join the Discord community. The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists. Read more about our partnership. Sign up for the “Brain Inspired” email alerts to be notified every time a new “Brain Inspired” episode is released: To explore more neuroscience news and perspectives, visit thetransmitter.org. Since the 1940s and 50s, back at the origins of what we now think of as artificial intelligence, there have been lots of ways of conceiving what it is that brains do, or what the function of the brain is. One of those conceptions, going to back to cybernetics, is that the brain is a controller that operates under the principles of feedback control. This view has been carried down in various forms to us in present day. Also since that same time period, when McCulloch and Pitts suggested that single neurons are logical devices, there have been lots of ways of conceiving what it is that single neurons do. Are they logical operators, do they each represent something special, are they trying to maximize efficiency, for example? Dmitri Chklovskii, who goes by Mitya, runs the Neural Circuits and Algorithms lab at the Flatiron Institute. Mitya believes that single neurons themselves are each individual controllers. They're smart agents, each trying to predict their inputs, like in predictive processing, but also functioning as an optimal feedback controller. We talk about historical conceptions of the function of single neurons and how this differs, we talk about how to think of single neurons versus populations of neurons, some of the neuroscience findings that seem to support Mitya's account, the control algorithm that simplifies the neuron's otherwise impossible control task, and other various topics. We also discuss Mitya's early interests, coming from a physics and engineering background, in how to wire up our brains efficiently, given the limited amount of space in our craniums. Obviously evolution produced its own solutions for this problem. This pursuit led Mitya to study the C. elegans worm, because its connectome was nearly complete- actually, Mitya and his team helped complete the connectome so he'd have the whole wiring diagram to study it. So we talk about that work, and what knowing the whole connectome of C. elegans has and has not taught us about how brains work. Chklovskii Lab. Twitter: @chklovskii. Related papers The Neuron as a Direct Data-Driven Controller. Normative and mechanistic model of an adaptive circuit for efficient encoding and feature extraction. Related episodes BI 143 Rodolphe Sepulchre: Mixed Feedback Control BI 119 Henry Yin: The Crisis in Neuroscience 0:00 - Intro 7:34 - Physicists approach for neuroscience 12:39 - What's missing in AI and neuroscience? 16:36 - Connectomes 31:51 - Understanding complex systems 33:17 - Earliest models of neurons 39:08 - Smart neurons 42:56 - Neuron theories that influenced Mitya 46:50 - Neuron as a controller 55:03 - How to test the neuron as controller hypothesis 1:00:29 - Direct data-driven control 1:11:09 - Experimental evidence 1:22:25 - Single neuron doctrine and population doctrine 1:25:30 - Neurons as agents 1:28:52 - Implications for AI 1:30:02 - Limits to control perspective
TWiN discusses a study showing that repetitive injury reactivates HSV-1 in a human brain tissue model and induces phenotypes associated with Alzheimer's disease. Hosts: Vincent Racaniello and Tim Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Repetitive injury, herpes, and Alzheimers (Sci Signal) The tau of herpesvirus (TWiV 1187) Fishing for viruses in senile (TWiV 519) Timestamps by Jolene Ramsey. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv
Čeští vědci teď testují nové metody pro diagnostiku neurodegenerativních nemocí v průzkumu, kterého se účastní 4 tisíce respondentů. - Jak by mohl vypadat život jinde ve vesmíru a jakou roli v tom hrají proteiny? To zkoumala laureátka prestižní vědecké ceny Neuron 2024, jejíž objevy mají potenciál objasnit otázky o vzniku života na Zemi. - Ostravští vědci budou mít nový areál pro vývoj a testování samořiditelných aut, mobilních robotů nebo systémů se strojovým učením. Neposlouží jen akademikům, ale měla by pomoci i průmyslu celého regionu.
Joshua Burda Ph.D. joins the podcast to discuss how cells in the brain regulate response to injury and disease. As an Assistant Professor in the Department of Neurology at Cedars-Sinai Medical Center, Joshua applies his knowledge as a biomedical neuroscientist to uncover new treatment paths for patients with neurological disabilities. Joshua is interested in the functional recovery of neurological injuries, and his research reflects this. Over the course of his professional career, he has been published in multiple peer-reviewed scientific journals – including Nature, Neuron, and in the Proceedings of the National Academy of Science. Jump into the conversation to hear Joshua talk about: How spinal cord injury inhibits people's ability to live independent lives. The primary methods by which spinal cord injuries occur. How inflammation impacts brain and spinal cord injuries, and the importance of immune system response to traumatic events. The importance of maintaining a healthy cellular waste removal system. Neurological diseases and injuries are among the hardest for scientists to understand and treat. Fortunately, professionals like Joshua are leading the charge toward a future of neuroscientific innovation! Click here to engage with Joshua's work for yourself! Episode also available on Apple Podcasts: http://apple.co/30PvU9