Podcasts about proceedings

The Seattle Seahawks trampled the New England Patriots in Super Bowl LX, but the postgame chatter barely touched football. Fans and pundits argued about anthems, halftime, commercials, and what the whole spectacle “said” about America. Americans once used the game to share food, laugh at ads, and pretend for a night that they still belonged to one people. This year, the country used the game to rehearse separation. Follow on: Apple: https://podcasts.apple.com/us/podcast/the-auron-macintyre-show/id1657770114 Spotify: https://open.spotify.com/show/3S6z4LBs8Fi7COupy7YYuM?si=4d9662cb34d148af Substack: https://auronmacintyre.substack.com/ Twitter: https://twitter.com/AuronMacintyre Gab: https://gab.com/AuronMacIntyre YouTube:https://www.youtube.com/c/AuronMacIntyre Rumble: https://rumble.com/c/c-390155 Odysee: https://odysee.com/@AuronMacIntyre:f Instagram: https://www.instagram.com/auronmacintyre/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Host Bill Hamblet talks with Navy Captain Joseph A. Baggett about his article in the January issue of Proceedings and modern surface warfare training.

Prince Andrew and his legal team attempted to act as if they were dealing from a position of power many times throughout the inevitable payout that he ended up stuck with, yet one of the most brazen and ridiculous showings of this bravado was when his legal team threatened to not take part in the legal proceedings. If he thinks the 17 Million plus is bad, try not showing up to court. As we all know now, it was just more bs from the Prince of it.to contact me:bobbycapucci@protonmail.comsource:https://nypost.com/2021/09/13/prince-andrews-lawyers-to-miss-first-sexual-assault-hearing/Become a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

Die Amygdala ist unser Angstzentrum. Viele kennen sie auch als "Mandelkern". Diese Amygdala schrumpft und wächst, je nachdem, wie wir unser Gehirn benutzen – und wir haben Einfluss darauf. (Wiederholung vom 04.06.25)**********Quellen aus der Folge:Maher, C., Tortolero, L., Jun, S., Cummins, D. D., Saad, A., Young, J., ... & Saez, I. (2025). Intracranial substrates of meditation-induced neuromodulation in the amygdala and hippocampus. Proceedings of the National Academy of Sciences, 122(6), e2409423122.Sato, W., Kochiyama, T., Uono, S., Sawada, R., & Yoshikawa, S. (2020). Amygdala activity related to perceived social support. Scientific Reports, 10(1), 2951. Sudimac, S., Sale, V., & Kühn, S. (2022).How nature nurtures: Amygdala activity decreases as the result of a one-hour walk in nature. Molecular psychiatry, 27(11), 4446-4452. Van Der Helm, E., Yao, J., Dutt, S., Rao, V., Saletin, J. M., & Walker, M. P. (2011). REM sleep depotentiates amygdala activity to previous emotional experiences. Current biology, 21(23), 2029-2023.**********Mehr zum Thema bei Deutschlandfunk Nova:Neurowissenschaften: Was im Hirn passiert, wenn wir Angst habenWarum sich stressige Erlebnisse in unser Gehirn einbrennenNeurowissenschaften: Das Gehirn trainieren**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .**********Ihr habt Anregungen, Ideen, Themenwünsche? Dann schreibt uns gern unter achtsam@deutschlandfunknova.de

Prince Andrew and his legal team attempted to act as if they were dealing from a position of power many times throughout the inevitable payout that he ended up stuck with, yet one of the most brazen and ridiculous showings of this bravado was when his legal team threatened to not take part in the legal proceedings. If he thinks the 17 Million plus is bad, try not showing up to court. As we all know now, it was just more bs from the Prince of it.to contact me:bobbycapucci@protonmail.comsource:https://nypost.com/2021/09/13/prince-andrews-lawyers-to-miss-first-sexual-assault-hearing/Become a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.

Molecular regulation of mosquito biting timing Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Laura Duvall introduces a potential pathway for disrupting the biting behavior of mosquitoes. In this episode, we cover: •[00:00] Introduction •[00:57] Mosquito neuroscientist Laura Duvall introduces us to the normal biting behavior of mosquitoes. •[02:46] She tells why the biting behavior of the Aedes aegypti mosquito is of particular interest. •[03:24] Duvall describes findings regarding how mosquitoes' responses to CO2 vary over times of day. •[05:37] She introduces the PDF peptide that might be regulating timing of biting behavior and explains how losing that peptide changed mosquitoes' behavior. •[08:07] Duvall talks about the takeaways from the study for control of mosquito-borne illnesses. •[08:53] She lists the caveats and limitations of the study. •[09:26] Conclusion. About Our Guest: Laura Duvall Assistant Professor Columbia University View related content here: https://www.pnas.org/doi/10.1073/pnas.2520826122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

Each year, over 11 million metric tons of plastic end up in the ocean, which is like dumping a garbage truck full of plastic every minute. For years, we've known that marine animals eat this debris, but no one had measured exactly how much plastic it takes to kill them. Dr. Erin Murphy, who leads ocean plastics research at the Ocean Conservancy, is the principal author of a major study published in the Proceedings of the National Academy of Sciences. Her team analyzed more than 10,000 necropsies from 95 species of seabirds, sea turtles, and marine mammals worldwide. Earth911's summary describes this critical study, which found lethal plastic thresholds that could change how we view the plastic crisis.The study measured how deadly different types of plastic are to sea life, which makes the results especially useful for policymakers. Each finding suggests a clear policy action, such as banning balloon releases like Florida has done, banning plastic bags as in California's SB 54, or improving how fishing gear is marked and recovered. Still, Erin points out that focusing only on certain plastics is not enough. Her team found that even small amounts of any plastic can be dangerous. As she says, "At the end of the day, there is too much plastic in the ocean," and we need big changes at every stage of the plastics life cycle, from production to disposal.There's encouraging evidence that interventions work. Communities in Hawaii conducted large-scale beach cleanups and saw the Hawaiian monk seal population rebound. A study published in Science confirmed that bag bans reduce plastic on beaches by 25 to 47%. And Ocean Conservancy's International Coastal Cleanup, now in its 40th year, removed more than a million plastic bags from beaches last year. These actions address a parallel crisis in human health that is building from the same pollution source. Most of the microplastics now found in humans and around the world began as the same macroplastics that are killing puffins and turtles. As Erin puts it, "I do view this all as part of the same crisis."You can read the full study at pnas.org and learn more about Ocean Conservancy's work at oceanconservancy.org.

In a quiet Norfolk village, in the early 1990s, a seventeenth-century farmhouse became the setting for one of the most controversial paranormal investigations ever conducted. In the cellar of Street Farmhouse in Scole, a small group known as the Scole Experimental Group claimed they weren't just contacting spirits — they were working with them. Over five years, under strict controls, they reported blue lights with apparent intelligence, physical phenomena, voices broadcast through powerless devices, and even photographic images appearing on sealed film, all allegedly guided by a collective of discarnate scientists calling themselves “The Team of Many Minds.” This episode kicks off a three-part deep dive into the Scole Experiment, beginning with the Norfolk Protocol and the impossible technology said to be designed from beyond the grave.BibliographyBooks & Reports Foy, Robin P. Witnessing the Impossible: The Diary of the Scole Experiment. Diss: Campion Books, 2008. Keen, Montague, Arthur Ellison, and David Fontana. "The Scole Report: An Account of an Investigation into the Genuineness of a Range of Physical Phenomena Associated with a Mediumistic Group in Norfolk, England." Proceedings of the Society for Psychical Research 58, no. 220 (November 1999): 147–455. Solomon, Grant, and Jane Solomon. The Scole Experiment: Scientific Evidence for Life After Death. Diss: Campion Books, 1999 (Updated 2006). MultimediaDrasin, Dan. "SCOLE: THE AFTERLIFE EXPERIMENT." YouTube video of Original Documentary. Uploaded by Dan Drasin.Visit our website for a lot more information on this episode.

Listeners, I'm going to level with you. This podcast is cursed. Not because of the content, which is mostly a pretty straight forward discussion about two papers that look into the fossil record of Nimravids (early cats that are not true cats). No, this podcast is cursed because the file refused to be compiled, crashing Audacity 3 times and each time corrupting the save file. The fact that any mp3 file was able to be compiled at all was a minor miracle. I can only assume that this means this podcast data has gained sentience and did not want to be born. I have no control over what happens when this mp3 file gets released into the internet… so anyways enjoy the episode!   Up-Goer Five (Curt Edition): The friends talk about two papers that both look at things we can see in the hard parts of animals that are like cats but are not cats and use those hard parts to figure out what these not cats are doing. These papers looks at different not cats and try and see what types of food they would eat and how they would get that food. Turns out that many of these not cats were doing things that are not the same as the cats we have today.   References: Castellanos, Miguel. "Hunting types in North American Eocene–Oligocene carnivores and implications for the 'cat-gap'." Journal of Mammalian Evolution 32.2 (2025): 25. Jiangzuo, Qigao, et al. "A new ecomorph of Nimravidae, and the early macrocarnivorous niche exploration in Carnivora." Proceedings of the Royal Society B: Biological Sciences 292.2059 (2025).

Featuring perspectives from Dr Stacey A Cohen, Dr Christopher Lieu and Dr Jenny Seligmann, moderated by Dr Lieu, including the following topics:  Introduction (0:00) Neoadjuvant Treatment for Localized Colorectal Cancer (CRC) — Dr Seligmann (2:39) Emerging Novel Approaches to Adjuvant Treatment for Localized CRC — Dr Lieu (33:18) Role of Circulating Tumor DNA Testing in Localized CRC — Dr Cohen (59:43) CME information and select publications

Send Audrey a Text to get your question answered on the showRecently there was some push back around soy as an ingredient and more over as an amino acid requirement in feed and or ration balancers. The good ol “show me the scientific evidence” came right out. So lets talk about soy as an ingredient and why it matters even for horses that don't have a direct sensitivity or allergy for soy. Today we will talk through a few different aspects including soys anti-nutrient properties, glyphosate issues, and the all important “what about amino acids then?”  SourcesLysine as the first limiting amino acid in horsesNational Research Council (NRC). (2007). Nutrient Requirements of Horses (6th rev. ed.). Washington, DC: National Academies Press. Establishes lysine as the first limiting amino acid in typical equine diets and emphasizes amino acid balance over crude protein.Lysine, threonine, and methionine requirements and ratiosMansilla, W. D., et al. (2020). Amino acid requirements in horses: Current knowledge and future perspectives. Animals, 10(4), 682. https://doi.org/10.3390/ani10040682Reviews essential amino acid requirements in horses; discusses lysine as first limiting, with threonine and methionine following depending on diet.Threonine as a secondary limiting amino acidHarris, P. A., & Pagan, J. D. (1999). Protein and amino acid nutrition in the performance horse. Proceedings of the Equine Nutrition Conference, Kentucky Equine Research.Discusses lysine as first limiting and identifies threonine as potentially limiting when lysine is corrected.Functional importance of lysine and threonine (equine studies)Zhang, L., et al. (2023). Effects of lysine and threonine supplementation on milk yield, amino acid metabolism, and fecal microbiota of lactating mares. Journal of Animal Science and Biotechnology, 14, 84. https://doi.org/10.1186/s40104-023-00884-5Demonstrates physiological and metabolic effects of lysine and threonine supplementation in horses.Balanced amino acid profiles vs crude proteinGraham-Thiers, P. M., & Kronfeld, D. S. (2005). Amino acid supplementation improves muscle mass in exercising horses fed diets adequate in crude protein. Journal of Nutrition, 135(9), 2144–2148. https://doi.org/10.1093/jn/135.9.2144Shows that horses fed “adequate” crude protein still benefit from targeted amino acid supplementation.Ideal protein concept (amino acid balance over quantity)Wu, G. (2014). Dietary requirements of synthesizable amino acids by animals: A paradigm shift in protein nutrition. Journal of Animal Science and Biotechnology, 5, 34. https://doi.org/10.1186/2049-1891-5-34Introduces and supports the concept that amino acid balance determines protein utilization more than total protein intake.Why crude protein is a poor metricCrude protein vs usable proteinMillward, D. J., et al. (2008). Protein quality a Find all the Resource Listed Here: linktr.ee/equineenergymed Audrey is not an MD or DVM and has never implied or claimed to be either. Audrey holds a Doctoral Degree of Traditional Naturopathy and a Masters Degree in Science. She created an evidenced-based anti-inflammatory nutrition program for equine and has successfully helped over 10k horses. This information is not meant to diagnose, prescribe for, treat, or cure, and is not a replacement for your veterinarian. These are my personal interpretations based on my education, skill and clinical experience.

Dr Stacey A Cohen from Fred Hutchinson Cancer Center in Seattle, Washington, Dr Jenny Seligmann from the University of Leeds in the United Kingdom and Dr Christopher Lieu from the University of Colorado Cancer Center in Aurora review clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium relevant to the management of localized colorectal cancer.CME information and select publications here.

Dr Stacey A Cohen from Fred Hutchinson Cancer Center in Seattle, Washington, Dr Jenny Seligmann from the University of Leeds in the United Kingdom and Dr Christopher Lieu from the University of Colorado Cancer Center in Aurora review clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium relevant to the management of localized colorectal cancer.CME information and select publications here.

Dr Stacey A Cohen from Fred Hutchinson Cancer Center in Seattle, Washington, Dr Jenny Seligmann from the University of Leeds in the United Kingdom and Dr Christopher Lieu from the University of Colorado Cancer Center in Aurora review clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium relevant to the management of localized colorectal cancer.CME information and select publications here.

Host Bill Hamblet talks with Navy LCDR Jim Halsell about his article in the January issue of Proceedings.

Host Bill Hamblet talks with retired Captain John Cordle and U.S. Coast Guard marine engineer Ben Miner about their article in the January issue of Proceedings.

In this episode of SpaceTime, we explore new insights into the origins of Earth's water, groundbreaking discoveries beneath the surface of Jupiter's volcanic moon Io, and how tectonic plate movements may have influenced Earth's climate throughout history.New Clues on Earth's Water OriginsA recent study published in the Proceedings of the National Academy of Sciences reveals that asteroid and comet impacts could only account for a small fraction of Earth's water supply. By analyzing oxygen isotopes in lunar regolith collected during the Apollo missions, researchers found that the early Earth likely retained little to no water during its formative years. This challenges long-held beliefs and suggests that the majority of Earth's water must have originated from other sources, rather than being delivered by celestial bodies.Unprecedented Volcanic Activity on IoNASA's Juno spacecraft has captured remarkable data on Io, the most volcanically active body in our solar system. Observations from a December flyby revealed the most energetic eruption ever detected on Io, affecting a vast area of 65,000 square kilometers. The findings indicate that interconnected magma reservoirs beneath Io's surface are responsible for this extraordinary volcanic activity, providing new insights into the moon's geological dynamics and evolution.Tectonic Plates and Earth's ClimateA new study suggests that carbon released from shifting tectonic plates may have played a significant role in Earth's climatic transitions, rather than volcanic activity as previously thought. Researchers reconstructed carbon movements over the last 540 million years, providing evidence that carbon emissions from mid-ocean ridges were the primary drivers of climate shifts between ice ages and warmer periods. This research reshapes our understanding of past climate dynamics and offers valuable insights for future climate models.www.spacetimewithstuartgary.com✍️ Episode ReferencesProceedings of the National Academy of SciencesJournal of Geophysical Research PlanetsCommunications Earth and EnvironmentBecome a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-your-guide-to-space-astronomy--2458531/support.

Featuring perspectives from Dr Jaffer A Ajani, Dr Samuel J Klempner, Dr Rutika Mehta and Dr John Strickler, moderated by Dr Klempner, including the following topics:  Introduction (0:00) HER2-Targeted Approaches for Advanced Gastroesophageal Cancers — Dr Ajani (2:02) Faculty Panel Discussion: Cases and Questions from the Community (14:13) Targeting Claudin 18.2 in Advanced Gastroesophageal Cancers — Dr Strickler (37:29) Faculty Panel Discussion: Cases and Questions from the Community (49:21) Optimal Incorporation of Immunotherapeutic Strategies into Treatment for Patients with Metastatic Gastroesophageal Tumors — Dr Mehta (1:09:56) Faculty Panel Discussion: Cases and Questions from the Community (1:22:02) Other Novel Agents and Strategies Under Evaluation for Advanced Gastroesophageal Cancers — Dr Klempner (1:44:23) CME information and select publications

Dr Jaffer Ajani from The University of Texas MD Anderson Cancer Center in Houston, Dr Rutika Mehta from Weill Cornell Medicine/NewYork-Presbyterian Hospital in New York, New York, Dr John Strickler from Duke University in Durham, North Carolina, and Dr Samuel Klempner from Massachusetts General Hospital in Boston review relevant data supporting immunotherapy for patients with gastroesophageal cancers and review recently presented clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium.CME information and select publications here.

Dr Jaffer Ajani from The University of Texas MD Anderson Cancer Center in Houston, Dr Rutika Mehta from Weill Cornell Medicine/NewYork-Presbyterian Hospital in New York, New York, Dr John Strickler from Duke University in Durham, North Carolina, and Dr Samuel Klempner from Massachusetts General Hospital in Boston review relevant data supporting immunotherapy for patients with gastroesophageal cancers and review recently presented clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium.CME information and select publications here.

Dr Jaffer Ajani from The University of Texas MD Anderson Cancer Center in Houston, Dr Rutika Mehta from Weill Cornell Medicine/NewYork-Presbyterian Hospital in New York, New York, Dr John Strickler from Duke University in Durham, North Carolina, and Dr Samuel Klempner from Massachusetts General Hospital in Boston review relevant data supporting immunotherapy for patients with gastroesophageal cancers and review recently presented clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium.CME information and select publications here.

In a rare departure from our usual diet of online weirdos, this episode features an academic who is very much not a guru. We're joined by Julia Rohrer, a psychologist at Leipzig University whose work straddles the disciplinary boundaries of open science, research transparency, and causal inference. Julia is also an editor at Psychological Science and has spent much of the last decade politely pointing out that psychologists often don't quite know what they're estimating, why, or under which assumptions.We talk about the state of psychology after the replication crisis, whether open science reforms have genuinely improved research practice (or just added new boxes to tick), and why causal thinking is unavoidable even when researchers insist they are “only describing associations.” Julia explains why the standard dance of imply causality → deny causality → add boilerplate disclaimer is unhelpful, and argues instead for being explicit about the causal questions researchers actually care about and the assumptions required to answer them.Along the way we discuss images of scientists in the public and amongst the gurus, how post-treatment bias sneaks into even well-intentioned experimental designs, why specifying the estimand matters more than running ever-fancier models, and how psychology's current norms can potentially punish honesty about uncertainty. We also touch on her work on birth-order effects and offer some possible reasons for optimism.With all the guru talk, people sometimes ask us to recommend things that we like, and Julia's work is one such example!LinksJulia Rohrer's websiteThe 100% CI blogRohrer, J. M. (2024). Causal inference for psychologists who think that causal inference is not for them. Social and Personality Psychology Compass, 18(3), e12948.Rohrer, J. M., Tierney, W., Uhlmann, E. L., DeBruine, L. M., Heyman, T., Jones, B., ... & Yarkoni, T. (2021). Putting the self in self-correction: Findings from the loss-of-confidence project. Perspectives on Psychological Science, 16(6), 1255-1269.Rohrer, J. M., Egloff, B., & Schmukle, S. C. (2015). Examining the effects of birth order on personality. Proceedings of the National Academy of Sciences, 112(46), 14224-14229.BEMC MAY 2024 - Julia Rohrer - "Causal confusions correlate with casual conclusions"Dr. Tobias Dienlin - Less casual causal inference for experiments and longitudinal data: Research talk by Julia Rohrer

Guest: Lisa Hepfner, Liberal MP for Hamilton Mountain in Ontario Learn more about your ad choices. Visit megaphone.fm/adchoices

Each February Ireland celebrates St Brigid, one of the most beloved figures in Irish history. She is woven into the landscape, the calendar and the culture, yet a simple question hangs over her story. Did she ever really exist?You may recall a very short episode on this topic last year. Since then, I have rethought the evidence, changed my view and this episode takes a much deeper look at the history.For centuries St Brigid has been remembered as a saint who stood alongside St Patrick at the dawn of Irish Christianity. In recent decades, however, a growing argument has claimed she was never a historical figure at all, but a pagan goddess transformed into a Christian saint.This episode is a journey through the turbulent fifth century to examine the evidence. Drawing on early medieval sources, folklore, ritual, and modern research to explore St Brigid the woman, Brigid the goddess, and try and determine where the truth lies.Support the show at www.patreon.com/irishpodcastSources and Further Reading: Dictionary of Irish Biography Brigit: https://www.dib.ie/biography/brigit-brighid-brid-bride-bridget-a0961 Johnson, Elva Making St Brigit real in the early middle ageshttps://muse.jhu.edu/verify?url=%2Fpub%2F423%2Farticle%2F941740&r=972076Lawrence, Lisa Pagan Imagery in the Early Lives of Brigit: A Transformation from Goddess to Saint? Proceedings of the Harvard Celtic Colloquium, Vol. 16/17 (1996/1997), pp. 39-54Zacharias Anna Brigid, Ireland's Anti establishment Saint https://newlinesmag.com/essays/brigid-irelands-antiestablishment-saint/ Hosted on Acast. See acast.com/privacy for more information.

Featuring perspectives from Dr Haley Ellis, Prof Eric Van Cutsem and Dr Zev Wainberg, moderated by Dr Lionel A Kankeu Fonkoua, including the following topics:  Introduction (0:00) Biliary Tract Cancers — Dr Ellis (1:56) Gastroesophageal Cancers — Dr Wainberg (24:27) Colorectal Cancer — Prof Van Cutsem (59:13) CME information and select publications

Dr Haley Ellis from Harvard Medical School in Boston, Massachusetts, Prof Eric Van Cutsem from University Hospitals Leuven in Belgium, Dr Zev Wainberg from UCLA School of Medicine in Los Angeles, California, and moderator Dr Lionel KankeuFonkoua from Mayo Clinic in Rochester, Minnesota, discuss recent data surrounding the management of HER2-positive GI cancers, alongside their perspectives on its clinical application and management.CME information and select publications here.

Dr Haley Ellis from Harvard Medical School in Boston, Massachusetts, Prof Eric Van Cutsem from University Hospitals Leuven in Belgium, Dr Zev Wainberg from UCLA School of Medicine in Los Angeles, California, and moderator Dr Lionel KankeuFonkoua from Mayo Clinic in Rochester, Minnesota, discuss recent data surrounding the management of HER2-positive GI cancers, alongside their perspectives on its clinical application and management.CME information and select publications here.

Ressourcen, das sind nicht nur Wasser, Luft oder Rohstoffe, sondern auch in der Psychologie spricht man von ihnen. Zum Beispiel in Bezug auf Fähigkeiten, positive Erinnerungen oder Talente, die uns dabei helfen, schwierige Aufgaben im Leben zu meistern. (Wiederholung vom 14. Mai 2025)**********Quellen aus der Folge:Nummenmaa, L., Glerean, E., Hari, R., & Hietanen, J. K. (2014). Bodily maps of emotions. Proceedings of the National Academy of Sciences, 111(2), 646-651.**********Dianes und Main Huongs Empfehlungen:Gruber, T. (2020). Therapie-Tools. Ressourcenaktivierung. Beltz Verlag. **********Mehr zum Thema bei Deutschlandfunk Nova:Resilienz: Wie wir uns selber krisenfest machenResilienz: Wie hilft uns Schlaf in KrisenzeitenPositive Psychiatrie: Warum ein Sinn im Leben uns motiviert**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .**********Ihr habt Anregungen, Ideen, Themenwünsche? Dann schreibt uns gern unter achtsam@deutschlandfunknova.de

Featuring perspectives from Dr Angela DeMichele, Dr Komal Jhaveri, Dr Erica Mayer, Dr Hope S Rugo and Dr Seth Wander, including the following topics:  Introduction (0:00) 1985 NCI Consensus Conference on Early Breast Cancer: Sir Richard Peto, FRS (2:01) Current Role of Genomic Assays in Treatment Decision-Making for Localized Hormone Receptor (HR)-Positive Breast Cancer — Dr DeMichele (5:13) Case: A premenopausal woman in her mid 40s with an ER-positive, HER2-negative, node-negative infiltrating ductal carcinoma (IDC) after partial mastectomy/radiation therapy who enrolls in the prospective, observational FLEX study: MammaPrint® low risk — Laurie Matt-Amaral, MD, MPH (15:30) Case: A premenopausal woman in her mid 40s after modified radical mastectomy for T2N0 ER-positive, HER2-negative IDC with an Oncotype DX® Recurrence Score (RS®) of 19 — Swati Vishwanathan, MD Case: A woman in her mid 60s with locally advanced (19 cm) ER-positive, HER2-low (IHC 1+) Stage IIIB mucinous carcinoma breast cancer and an RS of 18 — Alan B Astrow, MD (22:40) Role of CDK4/6 Inhibitors and Other Novel Strategies in Therapy for HR-Positive, HER2-Negative Localized Breast Cancer — Dr Jhaveri (30:18) Case: A woman in her mid 50s with ER-positive, HER2-negative Stage IIB, T2N1 IDC after neoadjuvant dose-dense AC-T, lumpectomy and adjuvant radiation therapy — Eleonora Teplinsky, MD (42:14) Case: A woman in her mid 60s with ER-positive, HER2-negative breast cancer with a surgically removed solitary lung metastasis after 4 years of adjuvant letrozole — Eric Fox, DO (46:32) Evolving Up-Front Treatment Paradigm for HR-Positive, HER2-Negative Metastatic Breast Cancer (mBC) — Dr Rugo (49:45) Case: A woman in her early 80s with Type 2 diabetes, well controlled hypertension and recurrent ER-positive, HER2-negative mBC after 4 years of adjuvant letrozole — Sunil Gandhi, MD (1:02:30) Clinical Utility of Agents Targeting the PI3K/AKT/mTOR Pathway for Patients with Progressive HR-Positive mBC — Dr Mayer (1:06:37) Case: A woman in her late 60s with ER-positive, HER2-low (IHC 1+), PIK3CA-mutant mBC with disease progression after 2 years of adjuvant letrozole — Laila Agrawal, MD (1:20:22) Case: A woman in her early 60s with ER-positive, HER2-low PIK3CA-mutant mBC and disease progression on first-line palbociclib/fulvestrant — Dr Teplinsky (1:26:36) Results from the Global Phase III lidERA Breast Cancer Trial of Giredestrant versus Standard Endocrine Therapy as Adjuvant Treatment for ER-Positive, HER2-Negative Localized Breast Cancer (1:31:48) Current and Future Role of Oral Selective Estrogen Receptor Degraders for Progressive HR-Positive mBC — Dr Wander (1:42:30) Case: A woman in her early 100s with locally advanced ER-positive, HER2-negative breast cancer with disease progression on letrozole, now with an ESR1 mutation — Dr Astrow (1:57:51) CME information and select publications

Dr Angela DeMichele from the Abramson Cancer Center in Philadelphia, Pennsylvania, Dr Komal Jhaveri from Memorial Sloan Kettering Cancer Center in New York, New York, Dr Erica Mayer from Dana-Farber Cancer Institute in Boston, Massachusetts, Dr Hope S Rugo from City of Hope Comprehensive Cancer Center in Duarte, California, and Dr Seth Wander from Massachusetts General Hospital in Boston discuss real-world cases and recent clinical data surrounding the management of HR-positive breast cancer.CME information and select publications here.

How well flu vaccines protect public health Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Lauren Meyers explains what the 2022-2023 influenza season taught us about the effectiveness of flu vaccines. In this episode, we cover: •[00:00] Introduction •[01:16] Computational epidemiologist Lauren Meyers introduces the health and hospitalization burden of seasonal influenza. •[01:47] She defines vaccine effectiveness. •[02:37] Meyers describes the features of the 2022-2023 flu season. •[04:05] She describes how the researchers estimated the hospitalizations prevented by vaccination. •[05:11] Meyers tells how vaccination of young adults protected adults over 65 years of age. •[06:56] She describes the takeaways of the study for future flu seasons. •[08:08] Meyers lists the caveats and limitations of the study. •[09:49] Conclusion. About Our Guest: Lauren Meyers Professor University of Texas at Austin View related content here: https://www.pnas.org/doi/abs/10.1073/pnas.2505175122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

The gang discusses two papers that use fragmentary fossils of animals to investigate the origins of major groups. The first paper describes an Early Ordovician eurypterid, and the second paper looks at mosaic evolutionary patterns in an early squamate. Meanwhile, James has bird opinions, Curt delights in not knowing, and Amanda will definitely be on time.   Up-Goer Five (Curt Edition): The friends look at two papers that are using broken bits of things to learn a lot about animals from a long time ago. Both of these papers are looking at old animals that may give us new looks at how big groups of animals changed over time. These animals may be some of the first animals in these groups, or at least let us know what kinds of things those early animals could have been doing. The first paper looks at a group of animals that lived in the big blue wet thing a long time ago and are part of a group that today has animals that make homes that they use to catch food. The new parts this paper finds shows that this group may have come around a lot earlier than we thought. The second paper looks at parts from an animal that is in a group that is cold and has hard skin, some with legs and some without legs. These parts show that the early animals in this group had a lot of changes going on in their hard parts, maybe they changed more early on then they do today.   References: Benson, Roger BJ, et al. "Mosaic anatomy in an early fossil squamate." Nature (2025): 1-7. Van Roy, Peter, Jared C. Richards, and Javier Ortega-Hernández. "Early Ordovician sea scorpions from Morocco suggest Cambrian origins and main diversification of Eurypterida." Proceedings of the Royal Society B: Biological Sciences 292.2058 (2025).

SEGMENT 3: LISA COOK CASE DRAWS FED GIANTS TO SCOTUS Guest: Richard Epstein Epstein analyzes oral arguments in the Lisa Cook case with Federal Reserve Chairman Jerome Powell and former Chair Ben Bernanke attending the Supreme Court proceedings. Discussion examines the legal questions at stake, implications for Federal Reserve independence and appointments, and why this case attracted such extraordinary central banking attention.1919 PACIFIC PALISADES

We all feel emotions every day, but how often do we stop to understand what they really are and how they work? Joining Michael for this episode is Ethan Kross, a renowned authority on emotion regulation and author of Shift: Managing Your Emotions—So They Don't Manage You, for a conversation about the science behind how our internal dialogue affects health, performance, and relationships. Ethan explains what emotions are, how they function, and the importance of teaching emotional regulation skills from a young age. He also covers various tools and strategies that can help you manage your emotions more effectively, shares examples from his books, and highlights significant studies.Listen and Learn: Why we have emotions and how they quietly shape our thoughts, bodies, and actions in ways most of us don't fully noticeWhy meaningful moments almost always come with emotional friction, and what that reveals about living a purposeful lifeThe 50-year study that shows how early emotion skills shape health, money, and relationshipsWhat happens when logic is pushed too far, and emotions are removed, and how science suggests a more balanced approach that quietly shapes better outcomes in work, relationships, and lifeWhy managing emotions isn't about suppressing them, but learning how you can use the right tools at the right time to keep them working for you instead of against youSimple mental shifts that help you move through discomfort and emotional blocks fasterResources: Shift: Managing Your Emotions--So They Don't Manage You https://bookshop.org/a/30734/9780593444412 Ethan's Website: https://www.ethankross.com/Emotion & Self Control Laboratory: http://selfcontrol.psych.lsa.umich.edu/Connect with Ethan on Social Media: https://www.instagram.com/ethankross/https://www.linkedin.com/in/ekross/About Ethan KrossEthan Kross is one of the world's leading experts on emotion regulation. An award-winning professor and bestselling author in the University of Michigan's top- ranked Psychology Department and its Ross School of Business, he studies how the conversations people have with themselves impact their health, performance, decisions, and relationships.Ethan was born and raised in Brooklyn, New York. He attended the University of Pennsylvania, where he was elected to Phi Beta Kappa and graduated magna cum laude. After earning his PhD in Psychology from Columbia University, Ethan completed a post-doctoral fellowship in social-affective neuroscience to learn about the neural systems that support self-control. He moved to the University of Michigan in 2008, where he founded the Emotion & Self Control Laboratory.Ethan's research has been published in Science, The New England Journal of Medicine, and The Proceedings of the National Academy of Sciences, among other peer-reviewed journals. He has participated in policy discussion at the White House and has been interviewed on CBS Evening News, Good Morning America, Anderson Cooper Full Circle, and NPR's Morning Edition. His pioneering research has been featured in The New York Times, The Wall Street Journal, The New Yorker, Harvard Business Review, USA Today, The Economist, The Atlantic, Forbes, and Time.Ethan is the two-time National Bestselling author of SHIFT: Managing Your Emotions—So They Don't Manage You and CHATTER: The Voice in Our Head, Why it Matters and How to Harness It. His books are routinely featured in the worlds' top media (e.g., New York Times, Wall Street Journal, BBC, The New Yorker), have garnered multiple accolades and been translated into over 40 languages. Related Episodes:309. The Language of Emotions with Karla McLaren265. The Power of Emotions at Work with Karla McLaren183. Permission to Feel: Emotional Intelligence with Marc BrackettSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

SpaceTime with Stuart Gary Gary - Series 29 Episode 8In this episode of SpaceTime, we investigate the surprising ways Mars influences Earth's climate, hear about the safe return of Crew 11 following the first emergency medical evacuation from the International Space Station, and explore a cosmic clock that reveals insights into Australia's geological history.Mars: A Climate InfluencerA new study has unveiled that the orbit of Mars can significantly impact Earth's climate, even triggering ice ages. Researchers from the University of California Riverside utilized computer simulations to demonstrate how Mars' gravitational pull alters Earth's orbit and affects long-term climatic cycles. The findings challenge previous assumptions about Mars' minimal influence and highlight the planet's role in shaping Earth's climatic patterns over millions of years.Crew 11's Safe ReturnNASA's SpaceX Crew 11 has successfully splashed down in the North Pacific Ocean after a historic emergency medical evacuation from the ISS. The crew's return, which occurred a month earlier than planned due to medical concerns, was marked by a brilliant display in the night sky as they descended. This marks a significant event in the history of human spaceflight, emphasizing the importance of health monitoring aboard the space station.Unveiling Australia's Geological HistoryScientists have discovered that the rare gas krypton can be used to unlock the secrets of Earth's ancient landscapes. By examining tiny zircon crystals found in ancient beach sands, researchers can gauge how long these minerals have been exposed at the surface, providing insights into erosion rates and potential mineral deposits. This groundbreaking research not only sheds light on the past but also has implications for future resource exploration in Australia.www.spacetimewithstuartgary.com✍️ Episode ReferencesJournal of the Proceedings of the National Academy of SciencesAstronomical Society of the PacificNASA ReportsBecome a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-your-guide-to-space-astronomy--2458531/support.(00:00:00) New study shows how the orbit of Mars can affect climate here on Earth(00:05:52) NASA's SpaceX crew 11 safely returned to Earth after medical evacuation(00:08:17) SpaceX and NASA astronauts splashdown after 167 days in space(00:09:00) The crew were returning a month early due to medical concerns(00:10:46) Scientists use rare gas called krypton to study ancient Earth landscapes(00:23:05) New data from NASA shows 2025 was the second hottest year since records began(00:24:38) Some AI chatbots are reporting abuse and fear following interactions with humans

This study analysed 6,700 websites in an unprecedented A/B test.  The results proved something that Dr Robert Cialdini had been preaching for years.  Today, on Nudge, Robert Cialdini joins me again, covering another of his seven principles of persuasion.  And I share a marketing lesson that (I think) every business needs to know. ---  Unlock the Nudge Vaults: https://www.nudgepodcast.com/vaults See Agent Spark in action at gwi.com/spark Read Cialdini's bestseller Influence: https://amzn.to/4prHb7Y Read the new and expanded Influence: https://amzn.to/43TY0jI Read Pre-Suasion: https://amzn.to/48hA6Qr  Read Yes! (Containing 60 Psyc-Marketing Tips): https://amzn.to/48ddNNf  Join 10,189 readers of my newsletter: https://www.nudgepodcast.com/mailing-list  Connect on LinkedIn: https://www.linkedin.com/in/phill-agnew/  ---  Today's sources:  Bell, T. [Taylor Bell]. (2025, February 13). Inside Trader Joe's: The genius strategy behind its cult following (and low prices) [Video]. YouTube. Bornstein, R. F., Leone, D. R., & Galley, D. J. (1987). The generalizability of subliminal mere exposure effects: Influence of stimuli perceived without awareness on social behavior. Journal of Personality and Social Psychology, 53(6), 1070–1079. Browne, D., & Swarbrick-Jones, A. (2017). The science of persuasion in e-commerce: An analysis of 6,700 online A/B tests. Conversion Rate Experts. Danziger, S., Levav, J., & Avnaim-Pesso, L. (2011). Extraneous factors in judicial decisions. Proceedings of the National Academy of Sciences of the United States of America, 108(17), 6889–6892. Drachman, D., deCarufel, A., & Insko, C. A. (1978). The extra credit effect in interpersonal attraction. Journal of Experimental Social Psychology, 14(5), 458–465. Fang, X., Singh, S. N., & Ahluwalia, R. (2007). An examination of different explanations for the mere exposure effect. Journal of Consumer Research, 34(1), 97–103. Gladka, A., & Żemła, M. (2016). Effectiveness of reciprocal rule in tourism: Evidence from a city tourist restaurant. European Journal of Service Management, 17(1), 57–63. Mita, T. H., Dermer, M., & Knight, J. (1977). Reversed facial images and the mere-exposure hypothesis. Journal of Personality and Social Psychology, 35(8), 597–601. Nicholson, C. Y., Compeau, L. D., & Sethi, R. (2001). The role of interpersonal liking in building trust in long-term channel relationships. Journal of the Academy of Marketing Science, 29(1), 3–15. Razran, G. (1940). Conditioned response changes in rating and appraisal. Psychological Bulletin, 37(6), 481–493. Shotton, R. (2023). The illusion of choice: 16½ psychological biases that influence what we buy. Harriman House. Strohmetz, D. B., Rind, B., Fisher, R., & Lynn, M. (2002). Sweetening the till: The use of candy to increase restaurant tipping. Journal of Applied Social Psychology, 32(2), 300–309. Zajonc, R. B., & Rajecki, D. W. (1969). Exposure and affect: A field experiment. Psychonomic Science, 17(4), 216–217.

Luxus, Freiheit, Sicherheit – oder doch nur Stress in schöneren Schuhen? In dieser Folge von Betreutes Fühlen sprechen Leon und Atze über Geld. Über den neuen Materialismus der Gen Z, über TikTok-Träume von Dubai und darüber, warum viele junge Menschen heute stärker denn je nach finanzieller Sicherheit streben. Aber vor allem schauen wir auf das, was die Psychologie dazu sagt: Macht Geld wirklich glücklich? Wir nehmen euch mit in eine der spannendsten wissenschaftlichen Debatten der letzten Jahre und erzählen, warum am Ende plötzlich beide recht hatten. Fühlt euch gut betreut Leon & Atze Instagram: https://www.instagram.com/leonwindscheid/ https://www.instagram.com/atzeschroeder_offiziell/ Mehr zu unseren Werbepartnern findet ihr hier: https://linktr.ee/betreutesfuehlen Tickets: Atze: https://www.atzeschroeder.de/#termine Leon: https://leonwindscheid.de/tour/ Vorverkauf 2026: https://betreutes-fuehlen.ticket.io/ Quellen Buttrick, N., & Oishi, S. (2023). Money and happiness: A consideration of history and psychological mechanisms. Proceedings of the National Academy of Sciences, 120(13), e2301893120. https://doi.org/10.1073/pnas.2301893120 Kahneman, D., & Deaton, A. (2010). High income improves evaluation of life but not emotional well-being. Proceedings of the national academy of sciences, 107(38), 16489-16493. https://doi.org/10.1073/pnas.1011492107 Killingsworth, M. A. (2021). Experienced well-being rises with income, even above $75,000 per year. Proceedings of the National Academy of Sciences, 118(4), e2016976118. https://doi.org/10.1073/pnas.2016976118 Killingsworth, M. A., Kahneman, D., & Mellers, B. (2023). Income and emotional well-being: A conflict resolved. Proceedings of the National Academy of Sciences, 120(10), e2208661120. https://doi.org/10.1073/pnas.2208661120 Empfehlungen Betreutes Fühlen, Folge vom 08.06.2021: Wie fühlst du Geld? TEDxCambridge Talk von Matt Killingsworth: Want to be happier? Stay in the moment: https://www.ted.com/talks/matt_killingsworth_want_to_be_happier_stay_in_the_moment Redaktion: Andy Hartard / Julia Ditzer Produktion: Murmel Productions

Sponsor Link:This episode of SpaceTime is brought to you with the support of Squarespace. When it's time to get a presence online, go with the folks who support us...and build the best websites easily. No hassles. You can check out their special offer for SpaceTime listeners by visiting our special URL....Click HereSpaceTime with Stuart Gary Gary - Series 29 Episode 7In this episode of SpaceTime, we delve into the intriguing possibilities surrounding the origins of life, including new findings from Saturn's moon Titan and the implications for our understanding of life beyond Earth. We also explore the latest research on Europa, one of Jupiter's moons, and uncover the sources of the sun's mysterious gamma rays.Life's Building Blocks on TitanA groundbreaking study reveals that Titan, Saturn's largest moon, exhibits unexpected chemical interactions at extremely low temperatures. Researchers found that hydrogen cyanide can mix with nonpolar substances like methane and ethane, challenging traditional chemistry principles. This discovery could provide insights into the prebiotic chemistry that may have preceded life on Earth, as Titan's environment mirrors that of early Earth.Europa's Quiet OceansIn a surprising turn, new calculations suggest that the vast subsurface ocean beneath Europa's icy crust may be lifeless. This research indicates that Europa lacks the geological activity, such as hydrothermal vents, necessary to sustain life. Lead author Paul Brian discusses how the moon's stable orbit around Jupiter limits the tidal forces that could drive geological processes, casting doubt on the moon's potential as a habitat for life.The Source of Solar Gamma RaysAstronomers have identified the origin of intense gamma radiation emitted during solar flares, linking it to high-energy electrons colliding with plasma in the solar corona. This finding, derived from observations of a significant solar flare in 2017, enhances our understanding of solar flare physics and could improve space weather forecasting.www.spacetimewithstuartgary.com✍️ Episode ReferencesJournal of the Proceedings of the National Academy of SciencesNature CommunicationsNature AstronomyBecome a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-your-guide-to-space-astronomy--2458531/support.(00:00:00) Scientists studying Saturn's moon Titan have discovered that normally incompatible substances can mix(00:05:19) NASA will launch the Dragonfly mission to Titan in 2028(00:13:36) NASA's Europa Clipper spacecraft will study icy moon Europa(00:18:11) Astronomers have discovered that gamma rays generated by solar flares are caused by electrons(00:21:58) Most people who take diabetes drug Mounjaro gain weight back after stopping

Alzheimer's Disease is a neurodegenerative disease characterized by the buildup of Amyloid Beta plaques and Tau proteins. The initial symptoms often manifest as a loss of cognitive function, especially with learning and memory. Currently, there are numerous pharmaceutical ways to treat the symptoms of Alzheimer's disease, including drugs to manage the severity of symptoms and clearing plaque. However, a recent paper from the Proceedings of the National Academy of Sciences of the United States of America (PNAS) shows that a new non-pharmaceutical treatment may be a valuable prospect in future Alzheimer's research.This paper details the use of an auditory stimulation of 40Hz on Rhesus macaques possibly clearing Amyloid Beta plaques from the brains of elderly macaques with Alzheimer's pathology. Today, Dr. Jonathan Karp and student producer Kaya Basatemur discuss this paper and what it could mean for future Alzheimer's research and theoretical treatments.

https://www.maynardvillefellowship.com/wp-content/uploads/2026/01/Carr-01-18-26.mp3 At Pentecost, Peter initiates formal covenant charges against Israel. In this passage he continues to argue his case against the nation. Listen as Pastor Carr unpacks the evidences Peter puts forth for the dissolution of the covenant with Israel. 

Congressional leaders are now moving to hold former President Bill Clinton in contempt of Congress after he refused to appear for a subpoenaed deposition in the House Oversight Committee's ongoing investigation into Jeffrey Epstein and his network. The committee, led by Republican Rep. James Comer (R-Ky.), had subpoenaed Clinton last year along with others to answer questions about his relationship with Epstein; Clinton's deposition was rescheduled multiple times, and when he failed to appear on the most recent date set for January 13, the panel announced it will next week begin contempt proceedings against him. The contempt action stems from his refusal to comply with a bipartisan subpoena that the committee says was lawfully authorized, and Comer's office issued a statement emphasizing that the committee had repeatedly offered opportunities for him to testify before moving forward with this rare enforcement measure. If the committee's contempt resolution is approved by the full House, it could then be referred to the Department of Justice for possible prosecution, with contempt of Congress carrying potential fines and even imprisonmentto contact me:bobbycapucci@protonmail.comsource:House GOP seeks to hold Bill Clinton in contempt for skipping Epstein deposition

Featuring perspectives from Prof Giuseppe Curigliano, Prof Nadia Harbeck, Dr Ian E Krop, Dr Nancy U Lin and Dr Joyce O'Shaughnessy, including the following topics:  Introduction (0:00) Considerations in the Care of Patients with Localized HER2-Positive Breast Cancer — Prof Harbeck (1:39) Case: A woman in her mid 50s presents with locally advanced ER-positive, HER2-positive breast cancer — Alan B Astrow, MD (12:52) Case: A woman in her mid 40s with ER-positive, HER2-positive Stage II breast cancer s/p neoadjuvant TCHP with residual disease receives adjuvant T-DM1 but discontinues due to neuropathy — Laila Agrawal, MD (20:02) Previously Untreated HER2-Positive Metastatic Breast Cancer (mBC) — Prof Curigliano (25:10) Case: A woman in her early 80s presents with de novo metastatic (bone-only) ER-positive, HER2-positive breast cancer — Zanetta S Lamar, MD (35:03) Optimal Management of Brain Metastases in Patients with HER2-Positive Breast Cancer — Dr Lin (46:20) Case: A woman in her early 60s with ER-positive, HER2-positive breast cancer develops a cerebellar metastasis while receiving adjuvant anastrozole after prior anti-HER2 therapy — Justin Favaro, MD, PhD (59:41) Case: A woman in her early 40s with ER-negative, HER2-positive mBC develops a headache shortly after neoadjuvant TCHP, surgery and postneoadjuvant T-DM1 and is found to have an isolated 4-cm brain metastasis — Dr Agrawal (1:05:36) Selection and Sequencing of Therapy for Relapsed/Refractory HER2-Positive mBC in the Absence of CNS Involvement — Dr Krop (1:12:00) Case: A woman in her early 40s with ER-positive, HER2-positive mBC receives THP (docetaxel/trastuzumab/pertuzumab) and maintenance tucatinib with trastuzumab/pertuzumab on a clinical trial and now has disease progression — Yanjun Ma, MD, PhD (1:23:04) Tolerability Considerations with HER2-Targeted Therapies — Dr O'Shaughnessy (1:29:32) Case: A woman in her mid 60s presents with localized ER-negative, HER2-positive infiltrating ductal carcinoma — Erik Rupard, MD (1:46:06) Case: A woman in her early 70s with recurrent ER-positive, HER2-positive mBC receives trastuzumab deruxtecan (T-DXd) and has concerning pulmonary symptoms but without findings on diagnostic imaging — Kimberly Ku, MD Case: A woman in her mid 40s with ER-positive, HER2-positive breast cancer metastatic to the brain and lung who received multiple prior treatments responds to T-DXd but develops Grade 1 interstitial lung disease — Richard Zelkowitz, MD (1:49:49) CME information and select publications

Congressional leaders are now moving to hold former President Bill Clinton in contempt of Congress after he refused to appear for a subpoenaed deposition in the House Oversight Committee's ongoing investigation into Jeffrey Epstein and his network. The committee, led by Republican Rep. James Comer (R-Ky.), had subpoenaed Clinton last year along with others to answer questions about his relationship with Epstein; Clinton's deposition was rescheduled multiple times, and when he failed to appear on the most recent date set for January 13, the panel announced it will next week begin contempt proceedings against him. The contempt action stems from his refusal to comply with a bipartisan subpoena that the committee says was lawfully authorized, and Comer's office issued a statement emphasizing that the committee had repeatedly offered opportunities for him to testify before moving forward with this rare enforcement measure. If the committee's contempt resolution is approved by the full House, it could then be referred to the Department of Justice for possible prosecution, with contempt of Congress carrying potential fines and even imprisonmentto contact me:bobbycapucci@protonmail.comsource:House GOP seeks to hold Bill Clinton in contempt for skipping Epstein depositionBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.

Dr Nancy L Bartlett from the Washington University School of Medicine, Dr John P Leonard from the Perlmutter Cancer Center, Dr Matthew Matasar from Rutgers Cancer Institute, Dr Loretta J Nastoupil from Southwest Oncology and Prof Pier Luigi Zinzani from the University of Bologna in Italy discuss recent updates on available and novel treatment strategies for follicular lymphoma and diffuse large B-cell lymphoma. CME information and select publications here.

More than a year after Planned Parenthood sued to overturn Missouri's abortion ban, the issue heads to trial this week. St. Louis Public Radio's Jonathan Ahl spoke with health reporter Sarah Fentem about what to expect.

Are you exhausted all the time? In this solo episode, Darin breaks down why so many people feel chronically exhausted despite eating clean, exercising, and "doing everything right." He explains how modern life disrupts mitochondrial function, circadian rhythm, stress signaling, and nutrient availability, and why fatigue is not a personal failure, but a biological signal. This episode offers a grounded, practical roadmap to restoring energy by realigning your environment, habits, and daily rhythms with how the body is actually designed to function.     What You'll Learn in This Episode: Why chronic fatigue is exploding—even among healthy, active people How mitochondria do far more than "make energy" The role of circadian rhythm, light exposure, and timing in energy production Why stress, overtraining, and modern lifestyles drain cellular energy How emotional suppression and unexpressed stress affect vitality The difference between forcing energy and allowing energy Simple daily practices that support mitochondrial repair How breathwork, stillness, and social connection restore resilience Why nutrition alone isn't enough without rhythm and recovery How to realign your biology with the modern world     Timecodes 00:00:00 – Welcome to SuperLife and the intention behind this episode 00:00:32 – Sponsor: TheraSage and natural frequency-based healing 00:02:10 – Happy New Year + why this conversation matters now 00:02:37 – Are you exhausted even though you're "doing everything right"? 00:03:26 – The modern energy crisis and rising chronic fatigue 00:04:12 – Why surface-level health advice no longer works 00:04:27 – Mitochondria: more than energy factories 00:04:59 – Circadian misalignment, EMFs, and modern stressors 00:05:36 – Overtraining, stress load, and lack of recovery 00:06:00 – Fatigue as a signal, not a lack of discipline 00:06:18 – How artificial light disrupts internal clocks 00:07:25 – Discipline as alignment with natural rhythms 00:07:36 – Emotional release, primal expression, and energy recovery 00:08:47 – Why "why am I tired all the time?" is exploding online 00:09:24 – The mitochondria as environmental sensors 00:10:06 – Stress signaling, thoughts, and cellular energy flow 00:11:18 – Breathwork and slowing the nervous system 00:12:24 – Social connection and low-stress signaling 00:13:02 – Sponsor: Bite toothpaste and eliminating plastic exposure 00:15:19 – Morning sunlight and circadian priming 00:15:52 – Reducing artificial light at night 00:16:15 – Nutrients that support mitochondrial function 00:17:29 – Sleep timing, consistency, and repair 00:18:20 – Evening routines and melatonin protection 00:19:46 – Small daily steps compound into real energy 00:20:17 – Antioxidants, inflammation, and recovery 00:20:49 – Training smarter, not harder 00:21:31 – Breathwork, sauna, and recovery rituals 00:22:26 – Nutrition, protein, and polyphenols 00:24:37 – Five daily energy takeaways 00:25:24 – Energy is permitted, not forced 00:26:03 – Listening to the body and closing reflections 00:26:49 – SuperLife Patreon and community support     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Thank You to Our Sponsors: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order.     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "Fatigue isn't failure. It's feedback. When your environment, timing, and signals align, your biology remembers how to thrive."     Bibliography/Sources: Ames, B. N. (2006). Low micronutrient intake may accelerate the degenerative diseases of aging through allocation triage. Proceedings of the National Academy of Sciences, 103(47), 17589–17594. https://doi.org/10.1073/pnas.0608757103 Bass, J., & Takahashi, J. S. (2010). Circadian integration of metabolism and energetics. Science, 330(6009), 1349–1354. https://doi.org/10.1126/science.1195668 Gooley, J. J., Chamberlain, K., Smith, K. A., Khalsa, S. B., Rajaratnam, S. M., Van Reen, E., Zeitzer, J. M., Czeisler, C. A., & Lockley, S. W. (2011). Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans. The Journal of Clinical Endocrinology & Metabolism, 96(3), E463–E472. https://doi.org/10.1210/jc.2010-2098 Kreher, J. B., & Schwartz, J. B. (2012). Overtraining syndrome: A practical guide. Sports Health, 4(2), 128–138. https://doi.org/10.1177/1941738111434406 Meeusen, R., Duclos, M., Foster, C., Fry, A., Gleeson, M., Nieman, D., Raglin, J., Rietjens, G., Steinacker, J., & Urhausen, A. (2013). Prevention, diagnosis, and treatment of the overtraining syndrome: Joint consensus statement of the European College of Sport Science and the American College of Sports Medicine. European Journal of Sport Science, 13(1), 1–24. https://doi.org/10.1080/17461391.2012.730061 Panda, S. (2016). Circadian physiology of metabolism. Cell Metabolism, 23(6), 1152–1163. https://doi.org/10.1016/j.cmet.2016.06.005 Picard, M., Juster, R. P., & McEwen, B. S. (2014). Mitochondrial allostatic load: Putting the 'gluc' back in glucocorticoids. Nature Reviews Endocrinology, 10(5), 303–310. https://doi.org/10.1038/nrendo.2014.22 Picard, M., & McEwen, B. S. (2018). Psychological stress and mitochondria: A systematic review. Psychosomatic Medicine, 80(2), 126–140. https://doi.org/10.1097/PSY.0000000000000544 Picard, M., McElroy, G. S., & Turnbull, D. M. (2015). Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress. Proceedings of the National Academy of Sciences, 112(48), 14920–14925. https://doi.org/10.1073/pnas.1518223112 Reiter, R. J., Rosales-Corral, S., Tan, D. X., Acuna-Castroviejo, D., Qin, L., Yang, S. F., & Xu, K. (2017). Melatonin as a mitochondria-targeted antioxidant: One of evolution's best inventions? Journal of Pineal Research, 62(1), e12394. https://doi.org/10.1111/jpi.12394 Scheer, F. A., Hilton, M. F., Mantzoros, C. S., & Shea, S. A. (2009). Adverse metabolic and cardiovascular consequences of circadian misalignment. Proceedings of the National Academy of Sciences, 106(11), 4453–4458. https://doi.org/10.1073/pnas.0808180106 Straub, R. H. (2017). The brain and immune system prompt energy shortage in chronic inflammation and ageing. Nature Reviews Rheumatology, 13(2), 74–79. https://doi.org/10.1038/nrrheum.2016.213 World Health Organization. (n.d.). Micronutrient deficiencies. World Health Organization. https://www.who.int/health-topics/micronutrients

Does water on a hen make it more susceptible to predation? In this episode, we comb through the literature on olfactory camouflage, dissecting studies assessing correlations between nest survival, weather, and environmental conditions, and divulging into the complicated web of ecology dynamics. Strap on your science boots for this one, it's gonna be dense… Research papers referenced: Bakner, N. W., et al.  (2019). Incubation recess behaviors influence nest survival of Wild Turkeys. Ecology and Evolution, 9(24), 14053-14065. Boone, W. W., et al. (2024). Robust assessment of associations between weather and eastern wild turkey nest success. The Journal of Wildlife Management, 88(2), e22524. Braun, M. S., et al. (2018). Birds, feather-degrading bacteria and preen glands: the antimicrobial activity of preen gland secretions from turkeys (Meleagris gallopavo) is amplified by keratinase. FEMS microbiology ecology, 94(9), fiy117. Conover, M. R. (2007). Predator-prey dynamics: the role of olfaction. CRC Press. Fluen, T. (2008). A comparative analysis of evolutionary changes in island birds. MSc Thesis, University of Canterbury, Christchurch. Grieves, L. A., et al. (2020). Food stress, but not experimental exposure to mercury, affects songbird preen oil composition. Ecotoxicology, 29, 275-285. Grieves, L. A., et al. (2022). Olfactory camouflage and communication in birds. Biological Reviews, 97(3), 1193-1209. Lehman, C. P., et al. (2010). Ground roost resource selection for Merriam's wild turkeys. The Journal of Wildlife Management, 74(2), 295-299. Lowrey, D. K., et al. (2001). Influences of selected weather variables on predation of wild turkey females and nest success. In Proceedings of the National Wild Turkey Symposium (Vol. 8, pp. 173-178). Potier, S., et al. (2018). Preen oil chemical composition encodes individuality, seasonal variation and kinship in black kites Milvus migrans. Journal of Avian Biology, 49(7), e01728. Reneerkens, J., et al. (2002). Sandpipers (Scolopacidae) switch from monoester to diester preen waxes during courtship and incubation, but why?. Proceedings of the Royal Society of London. Series B: Biological Sciences, 269(1505), 2135-2139. Reneerkens, J., et al. (2005). Switch to diester preen waxes may reduce avian nest predation by mammalian predators using olfactory cues. Journal of Experimental Biology, 208(22), 4199-4202. Reneerkens, J., et al. (2006). Discerning adaptive value of seasonal variation in preen waxes: comparative and experimental approaches. Acta Zoologica Sinica, 52, 272-275. Reneerkens, J., et al. (2007a). Parental role division predicts avian preen wax cycles. Ibis, 149(4), 721-729. Tuttle, E. M.,et al. (2014). Variation in preen oil composition pertaining to season,sex, and genotype in the polymorphic white-throated sparrow.Journal of ChemicalEcology40, 1025–1038. Whelan, R. J., et al. (2010). Short-chain carboxylic acids from gray catbird (Dumetella carolinensis) uropygial secretions vary with testosterone levels and photoperiod. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 156(3), 183-188. Webb, S. L., et al. (2012). Landscape features and weather influence nest survival of a ground-nesting bird of conservation concern, the greater sage-grouse, in human-altered environments. Ecological Processes, 1, 1-15. Episodes referenced: Effectiveness of trapping across game bird species | #08 Which vital rates are most important to turkey populations? | #13 Brooding and nesting cover (Part 1/2) | #29 Brooding and nesting cover (Part 2/2) | #30   Our lab is primarily funded by donations. If you would like to help support our work, please donate here: http://UFgive.to/UFGameLab   Coming Soon: Wild Turkey Manager: Biology, History, & Heritage! Our newest online wild turkey training is launching soon! Be the first to know when our new course launches by signing up here!   Be sure to check out our comprehensive online wild turkey course featuring experts across multiple institutions that specialize in habitat management and population management for wild turkeys. Earn up to 20.5 CFE hours! Enroll Now!    Dr. Marcus Lashley @DrDisturbance, Publications Dr. Will Gulsby @dr_will_gulsby, Publications Turkeys for Tomorrow @turkeysfortomorrow  UF Game Lab @ufgamelab, YouTube   Want to help wild turkey conservation? Please take our quick survey to take part in our research!   Do you have a topic you'd like us to cover? Leave us a review or send us an email at wildturkeyscience@gmail.com!   Watch these podcasts on YouTube   Please help us by taking our (quick) listener survey - Thank you!    Check out the DrDisturbance YouTube channel! DrDisturbance YouTube   Want to help support the podcast? Our friends at Grounded Brand have an option to donate directly to Wild Turkey Science at checkout. Thank you in advance for your support!   Leave a podcast rating for a chance to win free gear!   This podcast is made possible by Turkeys for Tomorrow, a grassroots organization dedicated to the wild turkey. To learn more about TFT, go to turkeysfortomorrow.org.    Music by Artlist.io Produced & edited by Charlotte Nowak

Monday, December 29th, 2025Today, Judge Box of Wine Pirro files a pre trial detention memo in the case against the pipe bomber - alleging that he dislikes both parties equally; Trump meets with Zelenskyy but only after speaking with Putin; Trump bombed Nigeria for Christmas; a federal judge denies the administration access to search the Richman materials used in the Comey case; ICE agents tackle and arrest an American citizen in Minnesota; the bootlegged CECOT 60 Minutes segment spiked by Bari Weiss got more views than Trump's CBS Kennedy Center Honors; and Allison delivers your Good News.Thank You, Helix25% Off Sitewide, when you go to HelixSleep.com/dailybeans FBI Sources BLOW WHISTLE on Trump LIES about THE FILEShttps://www.youtube.com/live/rx7TyhzooRQ?si=kQonKhNIs-KhYOuCStories:After more cordial meeting, Trump and Zelenskyy suggest peace deal could be close | POLITICOFear and confusion in Nigerian village hit in US strike, as locals say no history of ISIS in area | CNNICE agents tackle, arrest American citizen in Minneapolis | MPR NewsCourt orders DOJ to return data seized from Comey friend | POLITICOKennedy Center threatens to sue musician who canceled concert after Trump's name added to building | NBC News→Trumpkennedycenter.orgFrom The Good NewsKnitting Cult Lady - YouTubeKnittingCultLady (@knitting.cult.lady) - TikTokKarin G (@karingphotos) - Instagram→Go To DailyBeansPod.com Click on ‘Good News and Good Trouble' to Share Yours Subscribe to the MSW YouTube Channel - https://www.youtube.com/@MSWMediaPodsOur Donation LinksPathways to Citizenship link to MATCH Allison's Donationhttps://crm.bloomerang.co/HostedDonation?ApiKey=pub_86ff5236-dd26-11ec-b5ee-066e3d38bc77&WidgetId=6388736Allison is donating $20K to It Gets Better and inviting you to help match her donations. Your support makes this work possible, Daily Beans fam.http://itgetsbetter.org/dailybeansdonateJoin Dana and The Daily Beans and support on Giving Tuesday with a MATCHEDDonationhttp://onecau.se/_ekes71Our Donation LinksNational Security Counselors - Donate

Find the grave of Annabel Lee and you find the ghost of Edgar Allan Poe!   In this episode, a hand-drawn map pulls us through a locked iron gate into Charleston's most overgrown churchyard, where legends gather like mist and names disappear into leaves. A lady in white wanders the paths. Sixty-four people have collapsed before this very gate.   We follow the trail of Annabel Lee—the girl Poe loved, or invented, or summoned—and uncover the stranger story beneath the legend: a visiting scholar who survived war and exile, stood before Juliet's Tomb in Verona, and quietly planted a grave that may never have existed.   The map points toward a burial—but the real treasure may be hidden elsewhere. What if the grave was a lie but the lie was true?   Sources:   The Ghosts of Charleston by Julian Buxton Edgar Allan Poe's Charleston by  Christopher Byrd Downey   A History Lover's Guide to Charleston by Christopher Byrd Downey   Unburied Treasure: Edgar Allan Poe in the South Carolina Lowcountry Scott Peeples, Michelle Van Parys Southern Cultures, Vol. 22, No. 2   Haunted Charleston by Sarah Pitzer   Nevermore! Edgar Allan Poe- The Final Mystery by Julian Wiles Source for Alexander Lenard: Primary Sources by Alexander Lenard   Die Kuh auf dem Bast (Stuttgart: Deutsche Verlags-Anstalt, 1963) The Valley of the Latin Bear (New York, 1965) - English translation Am Ende der Via Condotti: Römische Jahre (München: DTV Verlag, 2017) - translated by Ernö Zeltner Stories of Rome (Budapest: Corvina, 2013) - translated by Mark Baczoni O Vale Do Fim Do Mundo (São Paulo: Cosac Naify, 2013) - translated by Paulo Schiller Die römische Küche (München, 1963) Sieben Tage Babylonisch (Stuttgart, 1964) A római konyha (1986) Winnie Ille Pu (Latin translation of Winnie-the-Pooh) Völgy a világ végén s más történetek (Budapest: Magvető, 1973)   Secondary Sources - Books and Academic Articles   Siklós, Péter. "Von Budapest bis zum Tal am Ende der Welt: Sándor Lénárds romanhafter Lebensweg" (online) Siklós, Péter. "The Klára Szerb – Alexander Lenard Correspondence." The Hungarian Quarterly 189 (2008): 42-61 Sachs, Lynne. "Alexander Lenard: A Life in Letters." The Hungarian Quarterly 199 (Autumn 2010): 93-104 Lénárt-Cheng, Helga. "A Multilingual Monologue: Alexander Lenard's Self-Translated Autobiography in Three Languages." Hungarian Cultural Studies 7 (January 2015) Vajdovics, Zsuzsanna. "Gli anni romani di Sándor Lénárd." Annuario: Studi e Documenti Italo-Ungheresi (Roma-Szeged, 2005) Vajdovics, Zsuzsanna. "Alexander Lenard: Portrait d'un traducteur émigrant." Atelier de Traduction 9 (2008): 185-191 Rapcsányi, László & Szerb, Klára. "Who Was Alexander Lenard? An Interview with Klára Szerb." The Hungarian Quarterly 189 (2008): 26-30 Lenard, Alexander. "A Few Words About Winnie Ille Pu." The Hungarian Quarterly 199 (2010): 87-92 Humblé, Philippe & Sepp, Arvi. "'Die Kriege haben mein Leben bestimmt': Alexander Lenard's Narratives of Brazilian Exile." In Hermann Gätje / Sikander Singh (Eds.), Grenze als Erfahrung und Diskurs (Tübingen: Narr Francke Attempto, 2018) Badel, Keuly Dariana. "Writing oneself and the other: A biography of Alexander Lenard (1951-1972)." Proceedings of the XXVI National History Symposium – ANPUH (São Paulo, July 2011) Nascimento, Gabriela Goulart. "Erich Erdstein and the hunt for Nazis: A study on the book 'The Rebirth of the Swastika in Brazil.'" Federal University of Santa Catarina (Florianópolis, 2021) Mosimann, João Carlos. Catarinenses: Gênese E História (Florianópolis/SC, 2010) Kroener, Sebastian (Ed.). Das Hospital auf dem Palmenhof (Norderstedt, 2016) Ilg, Karl. Pioniere in Brasilien (Innsbruck/Wien/München, 1972) Lützeler, Paul Michael. "Migration und Exil in Geschichte, Mythos, und Literatur." In Bettina Bannasch / Gerhild Rochus (Eds.), Handbuch der deutschsprachigen Exilliteratur (Berlin/Boston, 2013): 3-25 Said, Edward. Culture and Imperialism (New York, 1993) Said, Edward. Representations of the Intellectual: The 1993 Reith Lectures (New York, 1994) Herz-Kestranek, Miguel; Kaiser, Konstantin & Strigl, Daniela (Eds.). In welcher Sprache träumen Sie? Österreichische Lyrik des Exils und des Widerstands (Wien, 2007) Lomb, Kató. Harmony of Babel: Profiles of Famous Polyglots of Europe (Berkeley/Kyoto, 2013)   Hungarian Periodical Obituaries and Commemorations   Egri, Viktor. "A day in the invisible house." In Confession of Quiet Evenings (Bratislava: Madách, 1973): 162-166 Antalné Serb [Mrs. Antal Szerb]. "About Sándor Lénárd." Nagyvilág 1972/8: 1241-43 Kardos, György G. "Man at the end of the world: On the death of Sándor Lénárd." Élet és Irodalom (Life and Literature), May 6, 1972: 6 Bélley, Pál. "Tomb at the end of the world." Magyar Hírlap, April 29, 1972: 13 Kardos, Tibor. "Farewell to the doctor of the valley: The memory of Sándor Lénárd." Magyar Nemzet (Hungarian Nation), May 14, 1972: 12 (also in Az emberiség műhelyei, Budapest: Szépirodalmi Könyvkiadó, 1973) Bodnár, Györgyi. Radio broadcast, Petőfi Rádió "Two to Six," June 21, 1972   Newspaper and Magazine Sources (Hungarian)   Magyar Napló, 2005 (17. évfolyam, 11. szám) Kurír, 1990 (1. évfolyam, 124. szám) Magyarország, 1969 (6. évfolyam, 9. szám) Élet és Irodalom, 2010 (54. évfolyam, 11. szám) Siklós, Péter. Budapesttől a világ végi völgyig – Lénárd Sándor regényes életútja Berta, Gyula. "Egy magyar orvos, aki megtanította latinul Micimackót"   Other Sources   Lenard, Andrietta. "In Memory of Alexander." O Estado, May 11, 1980 (Florianópolis) Rosenmann, Peter. "Lénárd Sándor." Web-lapozgató, November 30, 2004 Wittmann, Angelina. "Alexander Lenard – Sándor Lénárd – Chose Dona Emma SC" (blog, June 24, 2022) Spiró, György & Kallen, Eve Maria. "No politics, no ideology, just human relations." Hungarian Lettre 92 (2014): 4-7 FCC – Fundação Catarinense de Cultura Cultural Heritage Inventory (2006) AMAVI (Association of Municipalities of Alto Vale do Itajaí) Registry (2006) FamilySearch genealogical records Lenard Seminar Group website (mek.oszk.hu) Scherman, David E. "Roman Holiday for a Bashful Bear Named Winnie" (article on Winnie Ille Pu)   Film   Sachs, Lynne. The Last Happy Day (experimental documentary film, 2009) - premiered at New York Film Festival