Podcasts about MX1

Another classic Webster vs Beaton battle in MX1, plus a Connolly double in MX2 – that was the story of Traralgon and round four of ProMX 2025. Recap all of the action with Nic Still and Trent Maher in MotoOnline's Express Podcast presented by FLY Racing, available now across the leading platforms. For complete information on FLY Racing, visit the brand online or stop in at your local retailer.

We catch up with the main protagonists from the Huck Cup & Mike Brown Memorial Motocross, including winner Tommy Searle, Brad Todd, Taylor Hammal, Luke Dean and Chris Mills, as well as the Jude Morris Celebration Race winner Ollie Bubb and MX1 victor Billy Bolt...Subscribe for tons more British Motocross, Enduro and Offroad content.Website - https://www.dirthub.co.uk/Podcast - https://www.dirthub.co.uk/podcasts/Instagram - https://www.instagram.com/dirthubuk/Facebook - https://www.facebook.com/dirthubuk

Ben and Paul review the first round of the 2025 Motul ACU British Motocross Championship, which kicked off at Hawkstone Park in the latest episode of the All British Motocross Podcast. In this show, they chat about Conrad Mewse's stunning 1-1 in MX1 and the confidence-boosting race wins for Bobby Bruce and Billy Askew in MX2, plus loads more...Subscribe for tons more British Motocross, Enduro and Offroad content.Website - https://www.dirthub.co.uk/Podcast - https://www.dirthub.co.uk/podcasts/Instagram - https://www.instagram.com/dirthubuk/Facebook - https://www.facebook.com/dirthubuk

The MX1 class of the 2025 Motul British Motocross Championship is previewed in the latest episode of the All British Motocross Podcast, with Ben and Paul chewing the cud on who they predict will be the contenders and favourites for the title this year...Subscribe for tons more British Motocross, Enduro and Offroad content.Website - https://www.dirthub.co.uk/Podcast - https://www.dirthub.co.uk/podcasts/Instagram - https://www.instagram.com/dirthubuk/Facebook - https://www.facebook.com/dirthubuk

Big news in Canadian moto as the reigning MX1 champion moves over from KTM to Yamaha. Matthes, Newf and Gauldy talk about that decision, World Vets FOMO and more in this Reaction pod

This week's Torq Moto Podcast Show sees part two of the Stephen Sword interview. In episode one ‘Swordy' opened up on his illustrious MX racing career and looked back in great detail, from where it all started, living near Lockerbie, Scotland and being a Team Green youth rider through to his best years racing the 125cc and MX2 world motocross championship where he held the red plate until bad luck and injuries ended his quest for a world title, before moving into MX1. In this episode, Stephen talks about how his racing career came to a close and what he did once it all stopped to where he is now as a riding coach. He also discusses the current state of the sport, the modern-day crop of riders, and racing in the Evo scene with hosts DocWob and Jeffro Perrett. In particular, Farleigh Castle and what it's like riding a CR500 when the throttle sticks wide open! Throughout both interviews, we see an informative, relaxed and enthusiastic Swordy, arguably a side of his personality not many people got to see in his racing heyday. It's all good stuff from a man who kept his cards close to his chest during his racing career. Don't forget to like and subscribe, as the Torq Moto team will be out in force at VMXDN Foxhill filming four live podcast shows over the event - coming to a screen near you soon! 

MX Farm was perhaps the most decisive day yet in the 2024 Penrite ProMX Championship, where Kyle Webster was able to strike in MX1 with a single round to run and Brodie Connolly clinched in MX2. Recap all of the action with Nic Still and Trent Maher in MotoOnline's Express podcast, available now across the leading podcast platforms.

Toowoomba's retro round saw Jed Beaton finally get back on top in MX1, while Honda Racing won the rest of the classes with Brodie Connolly (MX2), Jake Cannon (MX3) and Charli Cannon (MXW), plus we even had a one-off ProMX cameo from Jack Miller! Recap all of the action with Nic Still and Trent Maher in MotoOnline's Express podcast.

Round five of Penrite ProMX 2024 saw Kyle Webster begin to take control with his fourth MX1 overall of the season, as Alex Larwood was able to rise to the occasion in MX2, and there were a bunch of storylines outside of the winners, recapped by Nic Still and Dylan Wills in MotoOnline's Express podcast.

We're officially at the halfway point of the 2024 Penrite ProMX Championship and following Maitland's fourth round on the weekend, it's still all to play for between Kyle Webster and Jed Beaton just one point apart at the top of the MX1 table, while the MX2 title race tightened up following Ryder Kingsford's breakout win yesterday. Recap the action with Nic Still and Dylan Wills in MotoOnline's Express podcast.

Joe Stevens is joined by Danny Ham straight from the ProMX TV coverage to talk all things Gillman and how the day ran across the Championship classes of MX1, MX2 & MX3.As always our ProMX Race Coverage content is proudly supported by AMX Superstores.Check out https://www.amxsuperstores.com.au/ or visit one of their 30 + locations Nationwide.

A pivotal day of competition saw Kyle Webster reclaim the red plate in MX1 and Honda Racing teammate Brodie Connolly extend in MX2 as we approach the middle stages of the 2024 Penrite ProMX season. Recap the action with Nic Still and Trent Maher in MotoOnline's Express podcast, available now across the leading podcast platforms.

Paul and Ben Rumbold Preview the 2024 Dirt Store ACU British Motocross Championship, delve into the contenders in MX1 and MX2, and make their predictions as to who will make the top five come the culmination of the eight-round championship.Subscribe for tons more British Motocross, Enduro and Offroad content.Website - https://www.dirthub.co.uk/Podcast - https://www.dirthub.co.uk/podcasts/Instagram - https://www.instagram.com/dirthubuk/Facebook - https://www.facebook.com/dirthubuk

With Nathan Crawford and Jed Beaton splitting the MX1 moto wins and Brodie Connolly storming away with the MX2 double, Horsham's second round of Penrite ProMX 2024 produced another intriguing day of competition. Recap the action with Nic Still and Trent Maher in MotoOnline's Express podcast.

Join me for a summary looking at miniscrews, looking at where the answer to successful TAD placement lies, in research or clinical practice. The reasons for higher failure rates than others with TADs was explored through 3 key factors; insertion torque, site selection and root proximity. Evaluation of both scientific and clinical processes were described by Sebastian Baumgartel at the British Orthodontic Conference, as the Northcroft lecture.   Is torque a factor in TAD success? Torque study – compression during insertion Motoyoshi 2006 ·      High torque – 60% ·      Low torque = 72% ·      Medium torque – 92% Understanding ·      Low torque = low compression, low primary stability - early failure as not engagement with screw ·      High torque = high compression, early success, but greater resorption after insertion, remodelling results in a resorption process ·      Medium = best of both = sufficient compression for primary stability, not high enough to cause resorption remodelling Ideal ·      Ideal torque range – 10 Ncm Shantavasinkal 2016 o   Study of buccal tads ·      Sebastian's empirical experience between 10-25Ncm depending on site   Rules: ·      Aim for medium torque ·      Target 10Ncm ·      Exceed 10Ncm on palate acceptable   What is the best site for TAD insertion?   Keratinised gingiva ·      Evidence - states no difference  Lim 2009, Chen 2008, Park 2006, Cheng 2004 ·      Non Keratlised – depends on mobile or non mobile, with non-mobile higher success rate Viwattanatipa 2009 ·      2mm apical to muco-gingival junction o   zone of opportunity   Target zones and site o   No roots o   Consistent cortical bone o   More tolerant to higher torque o   Attached gingiva with low mobile mucosa     Is there ideal bone? ·       = if ideal torque = ideal cortical plate thickness §  1-1.5mm cortical plate thickness ·      CBCT can be overkill, using research sites for average sites     Ideal site: –      1st premolar region  (transverse)  Sebastian 2009 –      2 mm away from mid-palatal suture o   = creates ideal zone ‘Mx1'   Evidence of site selection success ·      98% Vs buccal 71% Houfar 2017 ·      84% Trainee success Sebastian 2020 ·      Success of Sebastian anterior palate 100%, maxillary buccal lowest 85%   Does root proximity influence TAD success? ·      Not just contact with roots, but proximity to root also causes failure Kuroda 2007, Asschericks 2008, Chen 2008   Understanding o   Increase root and PDL proximity =  bone stress increases = increase bone turnover = increase failure of TAD ·      4mm interradicular distance needed (depending on size of tad) to achieve 1 mm clearance from roots ·      Most buccal sites have less than 4mm (resolve through diverging roots, or sites with no roots)   What happens if TADs fail and we try again? –      Secondary insertion success o   58% (reduced by 33%) Park 2006 o    44.2%  (reduced by 36%) Uesugi 2017 o   58.1% buccal (reduced by 21%), 88.9% palatal (increased by 4%) Uesugi 2018 §  Uesugi 2018 showed buccal failure increases for secondary insertion, but palatal insertion increases success   For more education see Sebastian's TAD course: https://tadchallenge.com/tad-certification-course   I have no financial interest  

Fresh off his win in this years MXGP World Motocross Championship, Jorge was on vacation in the US doing some Supercross and we were lucky enough to get some time in between ride to record the podcast. I met Jorge earlier this year at the Arco event and we talked about making the podcast happen at some point through the season, but alas, we were never able to make it happen. That may have turned out for the better though as Jorge went on to wrap up his first MX1 title and have a great performance at MXON before owning the internet with footage of him at the KTM test track.On this episode of the podcast we talk about the relief he feels after winning his first MXGP title, his relationship with his father, being a prodigy in Europe and a factory rider since 11, his rivalry with Jefferey Herlings and Jett Lawrence, the 2023 Motocross of Nations, his plans to race Supercross and much more.To listen to all of our episodes before they are available to the public and without ads for just $11.99 per month, head to our membership website http://www.gypsy-tales.comSPONSORS:DRINK AG1: http://www.drinkag1.com/gypsytalesMake sure you use the code to get your years free supply of Vitamin D and 5 FREE travel packs!MANSCAPED: http://www.manscaped.comGet 20% Off + Free Shipping, with the code GYPSYGANGKRUSH OZ: https://krushoz.comDriTimes: http://www.dritimes.comFIST HANDWEAR: http://www.fisthandwear.comCODE: GYPSYGANG 15%DIXXON: http://www.dixxonquality.com.auTROPICAL AUTO GROUP: http://www.tropicalauto.com.auANTIGRAVITY BATTERIES: Use our affiliate code for a discount at: https://antigravitybatteries.com/ref/...SUBSCRIBE TO THE PODCAST ►https://www.youtube.com/channel/UCsBG...ADD GYPSY TALES ON INSTAGRAM ►https://www.instagram.com/gypsytalesp..See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Pro MX Rewind presented by Leatt. Trent is joined every week by Elijah Wiese to break down Round 7 of the Pro MX championship. The boys talk about all things QMP. Also Zac Watson the MX1 stand-out from QMP calls in to talk about his year and weekend. And the guy who dominated MX3 at QMP Jake Cannon calls in to discuss the win and his pant malfunctions Leatt is a head-to-toe brand that offers protection and style. Founded in 2001 by Dr. Chris Leatt with the sole purpose of keeping riders safe. This methodology remains today through extensive research development and testing. Find Leatt today at your local Retailer ⁠Leatt – Whites Powersports⁠ --- Send in a voice message: https://podcasters.spotify.com/pod/show/motolimited/message

The THOR post race interviews from ProMX R7 at QMP saw Joe Stevens catch up with privateer MX1 hero Joel Evans after his second moto holeshot, Luke Reardon chats about his Serco Yamaha signing, Zach Watson on his first THOR MX1 Top Ten finish along with Jayce Cosford, Noah Ferguson, Emma Millesivic, Taylah McCutcheon and Tahlia O'Hare.THOR MX via Gas Imports proudly support our post race interviews from ProMX. Check out the 2024 THOR MX Range available now https://gasimports.com.au/brands/thor/

MotoOnline's Express delivers a post-race review podcast from Gillman's fifth round of the 2023 Penrite ProMX Championship, as Nic Still and Dylan Wills break down the weekend's results as we start to see the MX1 title chase tighten up at the top of the standings.

MotoOnline.com.au's MotoNow podcast is our take on all things happening at MotoOnline from our perspective. As we hit the halfway point of the season, Nic Still and Dylan Wills discuss their predictions for the MX1, MX2 and MX3 classes ahead of round five at Gillam, South Australia this Sunday, as well as a range of other topics.

The AMX Superstores ProMX Review show is back covering all things Maitland. MX1 class Privateer Zhane Dunlop joins host Joe Stevens in studio to analyse the action from Maitland over two days of on track action.Guests on tonight's episode are MX2 overall winner Rhys Budd from Serco Yamaha, ProMX TV Commentator Lee Hogan and MX3 Moto winner Jett Alsop. The Inside Dirt ProMX Race Coverage is proudly supported by AMX Superstores.www.amxsuperstores.com.auhttps://www.instagram.com/amxsuperstores/

MotoOnline.com.au's MotoNow podcast is our take on all things happening at MotoOnline from our perspective. In this week's edition, Nic Still and Dylan Wills talk about this weekend's two-day event at Maitland and what you can expect when the gates drop on Saturday. They also discuss the spread out points at the front of the MX1 championship, who to watch in MX2, and a whole lot more.

THOR Australia via GAS Imports brings you the post race pit interviews from Wodonga. Hear from Alex Larwood, Nathan Crawford, Noah Ferguson in MX2 and Kirk Gibbs, Max Purvis and Levi Rogers in MX1 on their fast reaction to how their day went in the challenging Wodonga conditions. 

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.15.536998v1?rss=1 Authors: Assou, S., Ahmed, E., Morichon, L., Nasri, A., Foisset, F., Bourdais, C., Gros, N., Wong, S., Petit, A. F., Vachier, I., Muriaux, D., Bourdin, A., De Vos, J. Abstract: Airway-liquid interface cultures of primary epithelial cells and of induced pluripotent stem cell-derived airway epithelial cells (ALI and iALI, respectively) are physiologically relevant models for respiratory virus infection studies because they can mimic the in vivo human bronchial epithelium. Here, we investigated gene expression profiles in human airway cultures (ALI and iALI models) infected or not with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using publicly available and our own bulk and single-cell transcriptome datasets. SARS-CoV-2) infection significantly increased the expression of interferon-stimulated genes (IFI44, IFIT1, IFIT3, IFI35, IRF9, MX1, OAS1, OAS3 and ISG15) and inflammatory genes (NFKBIA, CSF1, FOSL1, IL32 and CXCL10) at day 4 post-infection, indicating activation of the interferon and immune responses to the virus. Extracellular matrix genes (ITGB6, ITGB1 and GJA1) also were altered in infected cells. Single-cell RNA sequencing data revealed that SARS-CoV-2 infection damaged the respiratory epithelium, particularly mature ciliated cells. The expression of genes encoding intercellular communication and adhesion proteins also was deregulated, suggesting a mechanism to promote shedding of infected epithelial cells. These data demonstrate that ALI/iALI models help to understand the airway epithelium response to SARS-CoV-2 infection and are a key tool for developing COVID-19 treatments. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Pro MX Rewind presented by Leatt. Trent is joined every week by Elijah Wiese to break down Round 2 at Appin. After an absolutely scorching weekend, there were many questions answered but still so many questions unanswered. MX1 overall winner Aaron Tanti calls in to talk about his day, and so too does MX3 winner Ky Woods after a near-perfect day. Then another rider from Privateer Island Liam Jackson calls in after being followed by Elijah all day for the Privateer Profile. Leatt is a head-to-toe brand that offers protection and style. Founded in 2001 by Dr. Chris Leatt with the sole purpose of keeping riders safe. This methodology remains today through extensive research development and testing. Find Leatt today at your local Retailer  Leatt – Whites Powersports --- Send in a voice message: https://podcasters.spotify.com/pod/show/motolimited/message

Pro MX Rewind presented by Leatt. Trent is joined every week by Elijah Wiese to break down Round 1 at Wonthaggi. Such a devastating ending to the event but there were still lots of talking points from what we saw out of round 1. Also, the drama that has ensued since with the Wilson Todd and Nathan Crawford. and the MX1 class is still full of questions. Leatt is a head-to-toe brand that offers protection and style. Founded in 2001 by Dr. Chris Leatt with the sole purpose of keeping riders safe. This methodology remains today through extensive research development and testing. Find Leatt today at your local Retailer Leatt – Whites Powersports --- Send in a voice message: https://anchor.fm/motolimited/message

Australian Pro MX is back for 2023!! and with that so too is the Pro MX Rewind and Preview Podcast presented by Leatt. This year is set to be a massive year of racing with both MX1 and MX2 classes filled to the brim with talent and race winners. Trent is joined on the panel by Elijah Wiese and Bailey Malkiewicz to break down the off-season and discuss what 2023 has install for us. Leatt is a head-to-toe brand that offers protection and style. Founded in 2001 by Dr. Chris Leatt with the sole purpose to keep riders safe. This methodology remains today through extensive research development and testing. Find Leatt today at your local Retailer Leatt – Whites Powersports --- Send in a voice message: https://anchor.fm/motolimited/message

Show 102, Trent, and Nic are back. The boys are joined in the studio by KTM Australia's Kirk Gibbs. This is 12 months in the making and it is finally here. Kirk opens up about his 2022 season, the 2012 crash that nearly cost him everything, the 2015 MX1 championship, and Brendan Harrison talk as well. Serco Yamaha's newest signing Brad West calls into the show to discuss his debut in Adelaide, life in Dingo, if he should be worried about Jason and Fortnite talk. Congratulations to Nick Lindenberg who won the States Mx Wheel Giveaway. motolimited.au go and get the new merch now. www.serco.com.au roosystems.com.au ktrapparel.com.au FLY Racing mpesuspension.com.au propowder.com.au linkint.com.au qb4.com.au @t.maher83 @iamstillyn99 --- Send in a voice message: https://anchor.fm/motolimited/message

MotoOnline.com.au's MotoNow podcast is our take on all things happening at MotoOnline from our perspective. This time out, Alex Gobert and Moto Limited's Nic Still review a memorable 2022 Penrite ProMX season finale at Coolum, where the MX1, MX3 and MXW champions were crowned, look ahead to the Australian Supercross Championship, Motocross of Nations (MXoN) and much more.

MotoOnline.com.au's MotoNow podcast is our take on all things happening at MotoOnline from our perspective. This time out, Alex Gobert and Moto Limited's Nic Still preview the 2022 Penrite ProMX finals at Coolum, where the MX1 title will be going down to the wire, briefly recap last weekend at Queensland Moto Park and a bunch more.

* Activities started for the Great Solidarity Motocross Race 2022 Within the framework of the traditional festival of Playa del Carmen, the municipal president Lili Campos inaugurated the 2022 Great Solidarity Motocross Race, which is being held at the José Quiam Chan track. The president of Solidarity gave the flag for the race. The event brings together around a hundred competitors from various states in the country, as well as a large group of fans of this extreme sport. The president of the Marlins Riviera Maya motocross club, Raúl Méndez. He recalled that there were already years without competitions of this type. Among the first results, the winner of the MX1 category was Martín García, from the State of Colima. The one from MX2 was Gerardo Arturo, from Mérida, Yucatán. In the 50-60 Veterans category, first place went to Raúl Méndez Briceño. Other participating categories were: enduro, youth, female youth and children. *Gloria Trevi spectacularly opens the concerts in the Plaza 28 de Julio The headquarters of the great events on the occasion of the Feria del Carmen 2022 whose activities are concentrated in the fairgrounds of the CTM avenues with 75 * Cozumel restaurateurs are trained to act against extortion Given the increase in the number of extortion cases in restaurants in Cozumel, the Cyber ​​Police Unit of the Ministry of Public Security offered a course to avoid this *They will teach the art of painting murals From the measurement of space, planning and project design are the steps that will follow in a fun summer course. Summer will be colorful for children from 6 to 12 years old thanks to the initiative that Street Art Cancun and the School Community with Values --- Support this podcast: https://anchor.fm/cjr-news/support

Here what Trent & Nic have to say as they break down Round 4 of the Australian Pro MX Championships from Gillman in South Australia. The boys get the scoop on what's going on with the riders and break down what they saw. Aaron Tanati joins the boys to talk about his first overall win of the in the MX1 class and claiming the Red plate. Rhys Budd joins the boys to talk about his first career MX2 podium. MX3 moto 2 stand out Ty Kean also hops on to talk to the boys about his start to the season and MXW Winner Charli Cannon also hops on to talk about her year so far and plans for 2023. motolimited.au for more. --- Send in a voice message: https://anchor.fm/motolimited/message

MotoOnline.com.au's MotoNow podcast is our take on all things happening at MotoOnline. In this edition, Alex Gobert and Moto Limited's Nic Still preview the Gillman round of the 2022 Penrite ProMX Championship, looking ahead to the upcoming MX1 and MX2 action from our perspective.

MotoOnline.com.au's MotoNow podcast is our take on all things happening at MotoOnline. In this edition, Alex Gobert and Moto Limited's Nic Still recap the Mackay round of the 2022 Penrite ProMX Championship, looking back at the MX1 and MX2 action from our perspective.

G'day Legends! With Baker and Blair finally back in the home land, the boys are once again reunited to bring you another ripper episode. Baker gives as a run down of his trip over in Tassie for the 2022 Enduro Jam with a of couple WA legends like the one and only Jordan Prochyra who calls in to chat about it alomg side baker. We also hear from WA's own and 2021 ProMX MX2 Champion Kyle Webster who has a chat with the boys about the opening round of the 2022 ProMX season as well as how he is feeling about heading into the 2nd round in his MX1 debut. This episode is just full of goodness, a bunch of laughs and is just an all round phat time. We hope you enjoy this one legends! Thanks so much to all of our sponsors: Empire Cycles - https://empirecycles.com.au Westeffex - https://westeffex.com The Underclass - https://www.shoptheunderclass.com Karradale Meats - https://m.facebook.com/KarradaleMeats Perth Husqvarna - GasGas - https://www.perthhusqvarna.com.au Concept Coatings Design Co. - https://www.conceptcoatingsdesignco.com Elite Automotive Care - https://www.facebook.com/eliteautomotivecare Pro Pleat - https://pro-pleat.com Roleystone Brewing Co. - https://www.roleystonebrewingco.com Smarter Outdoors - https://www.facebook.com/smarteroutdoors 50/Fifty Productions - https://www.facebook.com/50Fiftyproductions Mundijong Mechanical & Mobile - https://www.facebook.com/mundijongmechanical TD Modula Granny Flats - https://tdgrannyflats.com.au Maxxis - https://www.maxxismoto.com.au Motorex - https://www.motorexoil.com.au Make sure to check us out on our socials as well: I nstagram - https://www.instagram.com/thebeersandbikesshow Facebook - https://www.facebook.com/thebeersandbikesshow YouTube - https://www.youtube.com/channel/UCqLrBN20co96VNFXBfR9Dow Cheers Legends!

MotoOnline.com.au's MotoNow podcast is our take on all things happening at MotoOnline. In this edition, Alex Gobert and Moto Limited's Nic Still look back at the weekend's 2022 Penrite ProMX Championship opener staged in Wonthaggi, recapping the MX1 and MX2 action from our perspective

Nathan Crawford joins me on the phone to go over his injury that occures 1 week out from he ProMX Championship. Nato and I then reflect on Rd 1 at Wonthaggi, with interviews with MX1 2nd place Aaron Tanti, MX2 riders Alex Larwood 2nd for the day and Noah Ferguson

I preview the first round of the ProMx to be held at Wontaggi, interviews with Dylan Wills as he steps up into the Husqvarna Factory Team, Hayden Mellross as he switches from Yamaha to GASGAS and Kyle Webster as he embarks on his rookie year in MX1, expert tips from Jackson Richardson and Cru Halliday

Los Kiroleros han charlado con Jon Idiakez líder vasco en motocross. El piloto de Zuzenak logró este fin de semana en Falces una gran victoria en la general de su categoría MX1 en la prueba puntuable para el campeonato de Euskadi.

Hemos felicitado a Jon Idiakez tras proclamarse el fin de semana campeón de Euskadi en MX1.

Carl Capolingua from Think Markets and Jason McIntosh from Motion Trader go in-depth and stock-specific. Stocks covered: AIS, MAD, APE, VAF, BGA, EGG, TAH, CMW, MX1 and HYD. Replacing our usual 'Stock of the day', the guests proposed Kleos Space (KSS) and Neometals (NMT) as their ' life-changing' stocks. See acast.com/privacy for privacy and opt-out information.

Det slutade med en tredjeplats i motocross-SM i MX1 klassen 2020 för Anton Nordström Graaf och det självklara målet för 2021 är SM-guld.

Det slutade med en tredjeplats i motocross-SM i MX1 klassen 2020 för Anton Nordström Graaf och det självklara målet för 2021 är SM-guld.

Where to ride in SW Ontario Canada.  Gphoer Dunes has top knotch track and trail facilities for all rides in Motocross, ATV, Dual Sport/Enduro.MAIN TRACKThe main feature of Gopher Dunes is our world famous 2km sand track. The course features man-made obstacles with a 40 rider starting gate and underground irrigation system. The track is groomed 4 days per week and irrigated 3 days per week (if applicable)TRAILSOur trail system offers 3 separate one-directional trails that are close to 10km each in length for bikes, ATV’s, and UTV’s. The trails are well marked and groomed several times per year offering something fun to ride from beginner to Pro. Our trails also feature a single track section for bikes only and a Mud trail for ATV’s and UTV’s only.BEGINNER TRACKOur beginner track is designed for those who are just getting started with off-road riding. The course is 1.2 km in length and is also the same course used for our Red Rider training programs for those who have never rode before. Check out our rider training section for more information.PEEWEE TRACKOur peewee track at Gopher Dunes is 1.3 kilometres in length with a hybrid underground irrigation system. This track is designed for 50cc and 65cc two-strokes along with up to 125cc 4-stroke bikes. This is a great course for kids who want to get the full track riding experience.SUPERCROSS TRACKOur Supercross track was built in 2016 and was designed for racers with advanced skills who like to jump. The course is made up of clay and the layout was constructed by Derek Schuster and our MX1 motocross Pro, Colton Facciotti.CORNER TRACKOur corner track was built give give riders a sport to work on practicing their cornering skills which as most racers know, is the most crucial skill set to have. The track features a wide variety of soil including clay, wood chips, dark loam, and of sand.Presented by Energy Powersports: energypowersports.ca#gopherdunes #mudbrats #andy78kerr #motocross#fanphotos#snowmobilesessions#energypowersportsSHARE YOUR SUMMER Adventure PHOTOS/VIDEO LINKS on a future episode - email along with a brief story/description mailto:fanphoto@mudbrats.com (HAVE  A VIDEO? Please DO NOT send a video file - just the link to vimeo or youtube)Donate (Buy us a round):  https://bit.ly/2KHTSuZ• Mudbrats ADV Subscribe:  https://www.youtube.com/subscription_center?add_user=mudbratsPodcast: https://open.spotify.com/show/3FsgPV7hfJCd1eUDP5WOvm?si=rYSwp1o9RzmR4nGhumnarQSupport the show (https://bit.ly/2KHTSuZ)

Com diversos títulos nacionais e internacionais, nosso convidado tem uma carreira cheia de conquistas. Quem conhece motocross no Brasil com certeza já ouviu falar o nome de Jean Ramos. Durante esse podcast tivemos a oportunidade de conhecer ainda mais Jean, e que com muita humildade nos contou histórias marcantes do passado e seus projetos futuros para disputar a ponta da tabela no campeonato brasileiro de motocross na categoria MX1. Sinta conosco!

On this episode I'm joined by the reigning MX1 National Champion, Todd Waters.Some things we discuss:The physical side of motocrossTodd's emphasis on mindfulness and mental trainingRacing overseas in the MXGP and AMARacing for the Factory Husqvarna Team in MX1 and AORCImportance of strength training and nutrition/supplementationPost-career aspirationsTDUB Racing Gear@toddwaters47https://toddwaters.com.au/@tdub_auwww.younifyactive.com DKFITNESS at checkout for 15% offUse code DJK10 on all EHPlabs supplements for 10% offUse code DK10 on all Athletikan Sneakers for 10% offIntro by Will Sparks.Find this episode helpful? Share it with a friend or post a screenshot to your social media.

The first episode of the 2021 AMX Superstores MotoOnline.com.au ProMX Recap Show live from the Lynbrook AMX Superstore is here! Host Joe Stevens is joined Two Time MX1 Champion Matt Moss who will return to racing for the first time since 2016. Veteran champion of the sport Cameron Taylor joins the show to help preview the season and talk about his return the track this weekend in the 125 Cup. MotoOnline's Alex Gobert gives his thoughts on the upcoming championship and series contenders. Finally MX1 Privateer Joel Evans stops by to talk about his Privateer to Pro youtube and his goals for the 2021 MX1 season. As always please subscribe, like, rate and share Inside Dirt! The boys will back monday after Round 1 to recap and review all the action from Wonthaggi. But for now bring on the racing!

La segunda prueba del Campeonato de España de Motocross se celebró en Albaida (Valencia). Carreras muy emocionantes en todas las categorías, pero sobretodo en la de MX1. Eugenio y Pablo hablamos de lo que nos ofreció el streaming de la federación, analizamos lo ocurrido y además también compartimos las impresiones de varios pilotos: Valentín, Arcarons, Farres y Braceras nos explican que tal su fin de semana es esta carrera del nacional. La siguiente prueba se celebrará en Calatayud y seguro que veremos carreras muy emocionantes.

On the latest episode of the Inside Dirt Show Joe Stevens sits down for a one on one interview with 2019 MXD Champion Regan Duffy. Regan discusses his move to factory KTM for the upcoming ProMX season, where he will make his debut in the premier MX1 class. The boys also talk about Regan's MXON experience in 2019, along with his 2019 MXD Championship, his interrupted 2020 season and his plans for his future racing career. This is one you don't want to miss! As always please Subscribe, Share and rate the podcast and don't forget to head over to insdedirt.com.au for more content!

Space lasers. Yes, the future is here. We speak with Ohad Harlev, CEO of the revolutionary space-based storage in motion start-up, LyteLoop Technologies, to discuss how this innovative means of storing data securely in space using photonics (light) technology is set to change the way in which we think about and store an ever growing and increasingly crucial aspect of society, data. Ohad has held many senior positions during his career, including President of RRSat (now MX1) and COO at WorldLink Communications, and we dig deeper to understand how and why Ohad came to lead this new, exciting LyteLoop endeavour. We also discuss topics such the current state of the satellite and space industries, where they are heading, how COVID has impacted them, and of course we make sure to ask the truly important questions, like wine or beer and cats or dogs.

Scott Power from the Morgans Healthcare team speaks with Peter Rowland, CEO from Micro-X (ASX: MX1) where he explains the technology, its application, and upcoming catalysts for 2021.

The Inside Dirt Show is back for 2021 and episode #1 is packed full of preseason goodness for you! We have Joe Stevens and Aiden Williams co hosting with producer Darnell in studio. GasGas Australia new signing Aaron Tanti is on to talk about him re signing in Australia as opposed to racing AMA Supercross and his debut in MX1, Kirk Gibbs comes on to talk about signing to Honda and riding the new 2021 CRF450r, Scott Brewster owner of SB Motorsports Suzuki talks about being a team owner in the current state of the industry with COVID and privateer entrepreneur Joel Evans comes on from QLD to tell us about his Youtube series Privateer to Pro, his coaching schools and racing full time without a factory contract. Please subscribe, share and rate the podcast to help us blow Inside Dirt up in 2021!

Scott Power from the Morgans Healthcare team runs through a number of themes for 2021 together with some upcoming catalysts. Stocks mentioned include Pro Medicus (PME), Nanosonics (NAN), EBOS Group (EBO), Micro-X (MX1), Impedimed (IPD) Volpara Health Technologies (VHT), and ResMed (RMD).Check out more from Morgans:Visit the Morgans website: https://www.morgans.com.auCheck out our blog: https://www.morgans.com.au/BlogOn Facebook: https://www.facebook.com/MorgansAUOn Instagram: https://www.instagram.com/morgans.australiaOn Twitter: https://twitter.com/morgansAU#Healthcare #Technology #Morgans

The Morgans Healthcare provides an update on the following companies Promedicus (PME), Nanosonics (NAN), Resmed (RMD), Volpara (VHT), Virtus (VRT), Impedimed (IPD), and Micro-X (MX1)

Morgans Senior Analyst Scott Power recaps the healthcare picks for and what to look out for across the current active opportunities.Some of the companies Scott talks about are: Mach7 Technologies (ASX:M7T), Impedimed (ASX:IPD), Micro-X(ASX:MX1), and Neuron Pharmaceuticals (ASX:NEU).

Morgans Senior Analyst Scott Power recaps the healthcare picks for the week ending in 13, November 2020. Some of the active opportunities Scott details are Mach7 Technologies (ASX:M7T), Impedimed (ASX:IPD), Micro-X (ASX:MX1), and Neuron Pharmaceuticals (ASX:NEU).

Andrew Page from Strawman.com and Michael Wayne from Medallion Financial go in-depth and stock-specific. Stocks: GDG, EVS, NEA, MSB, MX1, URW, APX, SXY, CHN, RMS. The stock of the day is Kathmandu (KMD). See acast.com/privacy for privacy and opt-out information.

¿Sabía que se puede formar parte de un estudio clínico para ayudar a las personas con Alzheimer? En este episodio de JUNTOS Radio nos acompaña nuevamente nuestro gran amigo el Dr. Jaime Perales Puchalt, investigador en el tema de demencia. Él nos platica sobre la participación de las personas con Alzheimer en estudios clínicos, cómo se llevan a cabo y los recursos en español que podemos encontrar sobre esta enfermedad. ¡Esperemos disfrute de este episodio! Recursos del episodio:MedlinePlus español https://medlineplus.gov/spanish/alzheimersdisease.htmlAsociación de la Enfermedad de Alzheimer - Español  https://www.alz.org/?lang=es-MX1-800-272-3900 24/7University of Kansas Alzheimer's Disease Center - Español http://www.kualzheimer.org/en-español.html913-588-3716 Facebook: @kuadespanolUs Against Alzheimer's https://www.usagainstalzheimers.orgInstituto Nacional Sobre el Envejecimiento (NIA, por sus siglas en inglés) https://www.nia.nih.gov/health/espanol/temas Otros recursos confiables:Centro de Educación y Referencia Sobre el Alzheimer y las Demencias Relacionadas1-800-438-4380 www.nia.nih.gov/health/spanish/alzheimerCuidar a una persona con Alzheimer - Artículo https://www.nia.nih.gov/health/cuidar-persona-alzheimer-entender-mejor-enfermedad. Los recursos desarrollados en esta publicación reciben apoyo de National Library of Medicine (NLM), National Institutes of Health (NIH) bajo el acuerdo cooperativo número UG4LM012344. El contenido es solamente la responsabilidad de los autores y no necesariamente representa el punto de vista oficial de los National Institutes of Health. Conozca más acerca de nuestro amigo el Dr. Jaime Perales Puchalt, Ph. D., MPH:Jaime es Profesor Ayudante en University of Kansas Alzheimer's Disease Center. Estudió psicología y salud pública. Ha llevado a cabo su investigación en España, Inglaterra y los Estados Unidos de América y ha colaborado con equipos de investigación en otros países de la Unión Europea y las Américas. Su principal área de investigación son las desigualdades en demencia en la población latina. Para un tratamiento integral, para las necesidades de cada persona: All of Us. Ingrese a http://Joinallofus.org/bnm Síganos en las redes sociales de JUNTOSFacebook: @juntosKSYoutube: Juntos KSInstagram: juntos_radioTwitter: @juntosKSPágina web: http://juntosks.org WhatsApp: +1 913 229 4406 Centro JUNTOS para Mejorar la Salud Latina4125 Rainbow Blvd. M.S. 1076,Kansas City, KS 66160913-945-6635 Los recursos desarrollados en esta publicación reciben apoyo de National Library of Medicine (NLM), National Institutes of Health (NIH) bajo el acuerdo cooperativo número UG4LM012344. El contenido es solamente la responsabilidad de los autores y no necesariamente representa el punto de vista oficial de los National Institutes of Health. Developed resources reported in this [publications, press releases, internet sites] are supported by the National Library of Medicine (NLM), National Institutes of Health (NIH) under cooperative agreement number UG4LM012344. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. 

¿Sabía que se puede reducir el riesgo de desarrollar la enfermedad de Alzheimer? En este episodio de JUNTOS RADIO nos acompaña nuestro gran amigo el Dr. Jaime Perales Puchalt, investigador en el tema de demencia. Él nos platica cuáles son los factores de riesgo y síntomas de esta enfermedad además de cómo prevenirla. ¡Esperemos disfrute de esta gran charla! Recursos del episodio:MedlinePlus español https://medlineplus.gov/spanish/alzheimersdisease.htmlAsociación de la Enfermedad de Alzheimer - Español  https://www.alz.org/?lang=es-MX1-800-272-3900 24/7University of Kansas Alzheimer's Disease Center - Español http://www.kualzheimer.org/en-español.html913-588-3716 Facebook: @kuadespanolUs Against Alzheimer's https://www.usagainstalzheimers.orgInstituto Nacional Sobre el Envejecimiento (NIA, por sus siglas en inglés) https://www.nia.nih.gov/health/espanol/temasOtros recursos confiables:Centro de Educación y Referencia Sobre el Alzheimer y las Demencias Relacionadas1-800-438-4380 www.nia.nih.gov/health/spanish/alzheimerCuidar a una persona con Alzheimer - Artículo https://www.nia.nih.gov/health/cuidar-persona-alzheimer-entender-mejor-enfermedad Conozca más acerca de nuestro amigo el Dr. Jaime Perales Puchalt, Ph. D., MPH:Jaime es Profesor Ayudante en University of Kansas Alzheimer's Disease Center. Estudió psicología y salud pública. Ha llevado a cabo su investigación en España, Inglaterra y los Estados Unidos de América y ha colaborado con equipos de investigación en otros países de la Unión Europea y las Américas. Su principal área de investigación son las desigualdades en demencia en la población latina. Para un tratamiento integral, para las necesidades de cada persona: All of Us. Ingrese a http://Joinallofus.org/bnm Síganos en las redes sociales de JUNTOSFacebook: @juntosKSYouTube: Juntos KSInstagram: juntos_radioTwitter: @juntosKSPágina web: http://juntosks.org WhatsApp: +1 913 229 4406 Centro JUNTOS para Mejorar la Salud Latina4125 Rainbow Blvd. M.S. 1076,Kansas City, KS 66160913-945-6635  

Facciamo un recap sulla stagione MotoGP, SBK e Motocross dopo quasi un mese dallo scoppio dell'emergenza sanitaria che ha bloccato il mondo intero.

JSM guld i MX1 de två senaste åren och en 5:e plats totalt i MX1 SM 2018 är några resultat Emil Berggren haft genom åren. Vi pratar också supercross och lite enduro.

JSM guld i MX1 de två senaste åren och en 5:e plats totalt i MX1 SM 2018 är några resultat Emil Berggren haft genom åren. Vi pratar också supercross och lite enduro.

Gonçalo Reis foi campeão mundial de Enduro. No Campeonato Nacional de Motocross, Sandro Peixe consagrou o seu título em MX1. Em MX2, Diogo Grança sagrou-se campeão nacional. No Mundial de Superbikes, Jonathan Rea dominou em Itália. Na Fórmula 1, o Grande Prémio de França correu-se em Paul Ricard. A Mercedes reforçou a liderança do campeonato. António Félix da Costa não pontuou na Fórmula E, no E-Prix da Suíça. Tiago Monteiro teve mais uma ronda pouco produtiva na Taça do Mundo de Carros de Turismo. Apesar disso, venceu a categoria TCR nas 24h de Nurburgring. O Campeonato de Portugal de Ralis está ao rubro. Em Castelo Branco a luta foi ao segundo. O Troféu C1 Learn & Drive foi até ao Algarve. Estas e outras noticias para ouvires no Automobile desta semana. Design: Inês Militão Genérico: David Mateus Texto: David Pacheco e Madalena Costa Contatos: tresdoisumautomobile@gmail.com

O MotoGP foi à Catalunha e só 13 pilotos terminaram a corrida espanhola. Em 2022, o MotoGP regressa a Portugal ao Circuito Internacional do Algarve. Ivo Lopes dominou o fim-de-semana algarvio do Campeonato Nacional de Velocidade. No Campeonato Nacional de Motocross, já temos campeão em MX1. O Campeonato Mundial de Motocross foi até à Letónia. A Toyota #8 venceu as 24 horas de Le Mans. Dani Sordo venceu pela segunda vez no Campeonato Mundial de Ralis. Dupla vitória portuguesa em Jaramá na GT4 South European Series. Pedro Salvador dominou os Super Seven by Toyo Tires, no Circuito de Jaramá. O Troféu Mini teve emoção atéao fim, em Jaramá. Vitor Pascoal venceu o Rali Alto Tâmega. Carlos Martins e Daniel Amaral venceram o Rali de Monchique. João Fonseca dominou a Rampa de Santa Marta. Pedro Meireles não vai participar no Rali de Castelo Branco, a contar para o Campeonato de Portugal de Ralis. Design: Inês Militão Genérico: David Mateus Texto: David Pacheco e Madalena Costa Contatos: tresdoisumautomobile@gmail.com

Joe Stevens & Geran Stapleton in studio with guest Regan Duffy fresh off his Manjimump 15000 shock victory in the MX1 class. We talk about the AMA pro Motocross from Colorado and finish up with Jack Simpson as a guest checking in from the Finke desert race.

Esta semana el programa ha sido un mano a mano entre los hermanos Pablo y Eugenio Majó. Hablamos de las diferentes noticias del sector que nos ofrece www.mxvice.es El regreso de Herlings, Contrato de Tom Vialle y mucho más. Hablamos de la última prueba del nacional de Motocross en Alcañiz, donde Larrañaga y Valentin conseguían el título de Campeones de España de MX2 y MX1 respectivamente. En USA Cianciarulo ha vuelto a ganar y Roczen ha demostrado que está en un gran nivel de forma. Hablamos de algunos rumores de los fichajes y mucho más.

On the show tonight Aiden Williams and I go through Rd 1 at Appin held in arguably the worst conditions ever seen in 23 years of the MX Nationals. We interview MX1 winner Todd Waters, MX2 winner Jy Roberts and runner up Jay Wilson. 

This Canadian just scored 7th overall in the MX1 series up there and talks about how he did it, how he almost hung up the boots this winter, training with Maff in SoCal, his switch to Husky's and more

This Canadian just scored 7th overall in the MX1 series up there and talks about how he did it, how he almost hung up the boots this winter, training with Maff in SoCal, his switch to Husky's and more

Vi tar ett snack med Jimmy Wicksell. Totalfyra i MX1 efter två SM deltävlingar 2018. Vi pratar motocross, Gotland Grand National, Novemberkåsan och mycket mer.

Vi tar ett snack med Jimmy Wicksell. Totalfyra i MX1 efter två SM deltävlingar 2018. Vi pratar motocross, Gotland Grand National, Novemberkåsan och mycket mer.

A DM 2017 er lige om hjørnet! Lyt med når Nicholas Schrøder og Kasper Kvist bryder MX1- og MX2 feltet ned, og snakker med MX2 DM-kandidaten Mathias Gryning om hans crossfit-træning og hans sæsonforberedelser til 2017. Sponseret af: Kukkonen MX Service Yamaha Store Ringsted Hedegaard MX Track Service

Why is Harri Kullas riding MX1 and MX2? He explains exclusively.

Vi pratar med Jonas Algotsson, team coach i MC Sport Racing Team och deras MX1-stjärna Anton Wallstén.

Vi pratar med Jonas Algotsson, team coach i MC Sport Racing Team och deras MX1-stjärna Anton Wallstén.

Vi pratar med SM-guldmedaljören i MX1 om just SM, VM i USA, lag-VM i Frankrike och mycket mer.

Vi pratar med SM-guldmedaljören i MX1 om just SM, VM i USA, lag-VM i Frankrike och mycket mer.

Vi tar ett snack med SM-ledaren i MX1 klassen, Rasmus Sjöberg. Känslor att ha vunnit första deltävlingen och nu ha rödplåten.

Vi tar ett snack med SM-ledaren i MX1 klassen, Rasmus Sjöberg. Känslor att ha vunnit första deltävlingen och nu ha rödplåten.

Background Fingolimod (FTY720) is the first sphingosine-1-phosphate (S1P) receptor modulator approved for the treatment of multiple sclerosis. The phosphorylated active metabolite FTY720-phosphate (FTY-P) interferes with lymphocyte trafficking. In addition, it accumulates in the CNS and reduces brain atrophy in multiple sclerosis (MS), and neuroprotective effects are hypothesized. Methods Human primary astrocytes as well as human astrocytoma cells were stimulated with FTY-P or S1P. We analyzed gene expression by a genome-wide microarray and validated induced candidate genes by quantitative PCR (qPCR) and ELISA. To identify the S1P-receptor subtypes involved, we applied a membrane-impermeable S1P analog (dihydro-S1P), receptor subtype specific agonists and antagonists, as well as RNAi silencing. Results FTY-P induced leukemia inhibitory factor (LIF), interleukin 11 (IL11), and heparin-binding EGF-like growth factor (HBEGF) mRNA, as well as secretion of LIF and IL11 protein. In order to mimic an inflammatory milieu as observed in active MS lesions, we combined FTY-P application with tumor necrosis factor (TNF). In the presence of this key inflammatory cytokine, FTY-P synergistically induced LIF, HBEGF, and IL11 mRNA, as well as secretion of LIF and IL11 protein. TNF itself induced inflammatory, B-cell promoting, and antiviral factors (CXCL10, BAFF, MX1, and OAS2). Their induction was blocked by FTY-P. After continuous exposure of cells to FTY-P or S1P for up to 7 days, the extent of induction of neurotrophic factors and the suppression of TNF-induced inflammatory genes declined but was still detectable. The induction of neurotrophic factors was mediated via surface S1P receptors 1 (S1PR1) and 3 (S1PR3). Conclusions We identified effects of FTY-P on astrocytes, namely induction of neurotrophic mediators (LIF, HBEGF, and IL11) and inhibition of TNF-induced inflammatory genes (CXCL10, BAFF, MX1, and OAS2). This supports the view that a part of the effects of fingolimod may be mediated via astrocytes.

Colt 45 is a 3 time Canadian national champion. After two injury riddled season he's on a brand new program with TLD Honda in Canada and holds a 9 point lead over Mike Alessi in the MX1 standings. We chat with Colton about all things moto on route to his 2014 campaign.

In dieser Studie wurde die Kompetenz des Immunsystems von Turopolje (TxT), Deutsche Landrasse x Pietrain (LxP) und Deutsche Landrasse x Turopolje (LxT) verglichen. Die verschiedenen Rassen sind Vertreter einer alten und einer modernen Rasse und einer Kreuzung von beiden. Hauptziel war es zu untersuchen, ob sich die verschiedenen Rassen in ihrer Immunabwehr gegenüber einer Infektion unterscheiden und wie das Immunsystem durch Stressoren belastet wird. Außerdem wurde untersucht, ob sich LxT zur kommerziellen Mast eignet. Unterschiede in der Sekretion von Immunglobulin G und M im Kolostrum und reifen Milch der Deutsche Landrasse und Turopolje Sauen, sowie deren Aufnahme durch die Ferkel wurde mittels ELISA untersucht. Nach dem Absetzen der Ferkel wurden zwei getrennte Gruppen gebildet: Die erste Gruppe wurde mit einem attenuierten Lebendimpfstoff gegen das Porzine Reproduktive und Respiratorische Syndrom Virus (PRRS MLV) immunisiert, um eine Infektion zu simulieren. Die Fragmente des PRRS MLV wurden aus dem Serum, den Leukozyten, den Tonsillen und dem Lymphonodus tracheobronchale extrahiert und mittels qRT-PCR gemessen. Durch ELISA wurden die Konzentrationen der Interleukine-1β, 6, 10 und 12 gemessen. Die Genexpression von CD163, SIGLEC1, Mx1, TLR7 und TLR8, TRAF6, Myd88, Interleukin 1, 6, 8, 10, 12, TNFα, TGFβ und CXCL12 wurde näher untersucht. Innerhalb der nicht geimpften Gruppe untersuchte man den Einfluss von Stress auf das Immunsystem. Hierbei wurde die Konzentration von Interleukin 6, 10, 12 im Plasma mittels ELISA, die Genexpression in den Lymphozyten durch qRT-PCR von Interleukin 1β, 6, 10, 12 und TNFα bestimmt. Außerdem wurde eine mitogenstimulierte Lymphozytenproliferation mittels Lumineszenzmessung durchgeführt. Bei beiden Gruppen wurde ein Differentialblutbild angefertigt, um Veränderungen im weißen Blutbild untersuchen zu können. Weiterhin wurde mittels ELISA die Immunglobulinkonzentration G und M im Serum untersucht. Es wurde in der Gruppe der immunisierten Tiere sichtbar, dass die Rassen unterschiedlich auf die Vakzination reagierten. TxT zeigt keine Konzentrationsveränderung von Interleukin 1β im Plasma. Durch die unveränderte Konzentration des Interleukins könnten vermehrt zytotoxische T Zellen gebildet werden. Als Folge wird TNFα aufreguliert. TNFα inhibiert CD163, daher wird nur eine geringe Anzahl von B-Zellen aktiviert und es werden spezifische Antikörper gebildet. Im Gegensatz dazu reagieren die beiden anderen Rassen mit einer Immunantwort des Typs 2. Die oben beschriebene Inhibierung kann nicht stattfinden und es kommt zur Synthese der B-Zellen und zu einer erhöhten Konzentration an Immunglobulinen und spezifischen Antikörpern. Die Ergebnisse meiner Studie können tendenziell den Einfluss des Stresses auf das Immunsystem bestätigen. So deuten bei TxT die geringere Immunglobulinkonzentration und das Differentialblutbild darauf hin, dass die Immunreaktion auf Stress eher auf T-Zellen basiert (Immunreaktion Typ 1). Auch bei LxT und LxP scheint es, dass die Immunantwort Typ2 und eine Hochregulation der Genexpression von IL6 und die Konzentration im Plasma dominieren. Weiterhin besteht eine Tendenz, dass TxT auf Stress robuster reagieren als die beiden anderen Rassen. Nach der Schlachtung wurden die Schweinehälften aller Rassen und Gruppen mittels der SEUROP-Klassifizierung eingeteilt und bewertet. Bei Schweinen, die in der 25. Lebenswoche geschlachtet wurden, untersuchte man zusätzlich den Tropfsaftverlust und das intramuskuläre Fett. Im Vergleich der Schachtkörper und Fleischqualität schnitten die Tiere der Kreuzungsrasse (LxT) qualitativ am besten ab. Schlussfolgernd ist die Kreuzungsrasse (LxT) zur Mästung als Nutzungsrasse geeignet. Sie stellt eine Bereicherung innerhalb der kommerziellen Schweinefleischproduktion dar.

Last years MX1 champ just got back from California and in this podcast we talk about his career and the coming year.

Last years MX1 champ just got back from California and in this podcast we talk about his career and the coming year.

Influenza A virus infections are a major threat to the world poultry population. In the 19th century fatal influenza A virus infections have been described under the name “fowl plague” in chickens. The chicken is a natural host for this viral infection. The myxovirus resistance (Mx) gene which belongs to the group of interferon stimulated genes (ISG) was first described in mice. This protein confers protection against highly pathogenic influenza A viruses in mice. Mx proteins have been characterized in many species including mammals, poultry and fish. They belong to the family of large GTPase proteins exhibiting three highly conserved GTP-binding motifs at the amino-terminus and a leucin zipper at the carboxy-terminus. The GTPase activity was been shown to be essential for the antiviral activity of the Mx protein. Mx was also identified in the chicken, where it shows a significant degree of polymorphism. A polymorphism at aminoacid position 631 (serin versus asparagin) is thought to confer antiviral activity towards influenza A viruses. With the help of the RCAS retroviral vector system these two different chMx isoforms were examined in vitro and in vivo for their antiviral activity towards various pathogenic influenza A viruses. Neither in vitro nor in vivo antiviral activity of the chMx isoforms was detectable. In contrast overexpression of murine Mx1 and human MxA in the same form led to protection of the chicken embryo fibroblast cultures against influenza A viruses. Stimulation of chicken embryo fibroblasts with type I interferon induced chMx mRNA and protein expression as well as an antiviral state of the cells. However a chMx knock down mediated by siRNA did not lead to the loss of the antiviral state mediated by type I interferon. In summary, the in vitro studies did not provide evidence for a role of chMx in the antiviral state induced by type I interferon.

Guests include MX1 champ Dusty Klatt, Michael Willard, Chuck Mesley, Brett Lee, Ryan Gauld