Podcasts about tfg1

ToyCast is back and better than ever! This is Episode 194, this time TFG1Mike welcomes back Steve/Megatron as they talk about the awesome 3D printed Transformers Decepticon Command Chair from the Nemesis that Steve made for Mike, and so much more! Check it out! as we are back Talkin' Toys here on ToyCast!!INTERACT WITH THE GCRN FOLLOW US ON X! and LIKE US ON FACEBOOK!GAMER NEWS STORIES, HERE, HERE, and HERE!USE TFG1Mike's LinkTree to Follow Him!!Follow Steve/Megatron on X!, Instagram, and Threads!ToyWorldOrder!POPPIN' OFF TOYS! Follow Them on X! Facebook and Instagram!Pixel Dan's The Toys of He-Man and The Masters of the Universe!!!UNLEAS THE TOY GEEK IN YOU!!!!!

15 YEARS!!!!! Can you believe it? The TFG1 Podcast is 15 Years Old! In celebration we are giving you 15 NEW Episodes! This time around join TFG1Mike and Mike Seibert, as they have a wonderfully G1 conversation about The Cybertronic Spree's Transformers 1986 album! The TFG1 Podcast is back folks! You won't believe your ears!USE TFG1Mike's LinkTree to Follow Him!!LISTEN TO MSRP!! and 2Mikes2Furious!!Also follow Mike on X!This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/2922319/advertisement

In Episode 422 of Altered Geek Steve Megatron is joined by TFG1Mike!!! Tune in to hear what Steve and Mike have to say about the rabbit holes that they just can't get out of! From TV, Film, and other content, to toys, 3-D printing, and something soooo dumb, but TFG1 is soooo proud of this! Get ready for how we approach the GEEK and ALTER IT, all this and more! Only on Altered Geek!!!!!Use the Hashtag #WhatsGeekyToYou with what you're geeking out to this week and we'll try to feature your topic in a future episode!Use TFG1Mike's LinkTree to Follow Him!!Follow Steve/Megatron on X!, Instagram, and Threads!This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/2921918/advertisement

In Episode 424 of All Things Transformers, Steve and Mike are back to talk about the Hasbro Pulse Con reveals, so much and more! We are talkin' Transformers all the time here on All Things Transformers! As always we want to "UNLEASH THE TRANSFORMERS GEEK IN YOU!"

In Episode 285 of All Things Transformers TFG1Mike gets the Transformers Origins story of Snazzy Mike from The Transmissions Podcast! You are not gonna wanna miss this! We talk about his fave characters, fave Transformers era, from comics, to toys, to the bayverse, and back to the cartoons, plus so much more. So join us as we transform and transcend ATTF once more. This is the original Robots in Disguise Podcast of the GCRN.

In Episode 271 of All Things Transformers TFG1Mike gets the Transformers Origins  story of Charles aka Big C from The Transmissions Podcast! You are not gonna wanna miss this! We talk about his fave characters, fave Transformers era, from comics, to toys, to the bayverse, and back to the cartoons, plus so much more. So join us as we transform and transcend ATTF once more. This is the original Robots in Disguise Podcast of the GCRN.

2017 is here, and it's a brand new year! Steve "Megatron" and  TFG1Mike reflect on the career of Dick Gautier, most will know him as the voices of Season 3-4 Rodimus in TFG1, and Serpentor in G.I. Joe. He was also Hymie the Robot in Get Smart. So grab some energon drinks, sit back, relax, and listen to us talk Transformers! Only on All Things Transformers Version 3.0. Transform and Transcend! Welcome to the revival of All Things Transformers v3.0! Here we are hoping to bring a different take to all the Transformers Discussions from week to week. This will not be a weekly show and it will be bi-weekly to monthly. This is the original Robots in Disguise Podcast of the GCRN. Join Steve Megatron and TFG1Mike as we bring in a diverse group of guests to talk Transformers with us.To subscribe to the show, click here.Email us: feedback@geekcastradio.comTweet us: @AllThingsTFv3Download: ATTFv3 Episode 58Geeks:Steve "Megatron" PhillipsMike "TFG1" Blanchard

Steve and Dodd join forces to defeat the Furry alliance... Just kidding. We embark on the journey with TFG1 only in a segment this week and discuss the happenings in life, tv, film, health side projects, flint city water, the GCRN Awards and of course we respond to last week when we had the pleasure of speaking with Ramona the SportsGalPal, who you can hear on BlogTalkRadio as well as on SportsGalPal.com and iTunes.All this and more on this week's AGU! We hope you continue to enjoy the episodes and please feel free to respond to any and all feedback methods. We will read and reply on the show. Topic suggestions also welcome. So get Altered, Get Geeky with the Altered Geeks.Your Geek Question for the WeekIf we could have guests on from other places, who would you like to see?What do you look for in a podcastWhat would you like to see in the episode next week?Is there anything you'd like us to cover? Let us know! Geeks:Steve "Megatron" PhillipsMike "Birdman" Dodd

Gene transcription is a fundamental process of the living cell. Eukaryotic transcription of messenger RNA requires the regulated recruitment of the conserved transcribing enzyme RNA polymerase (Pol) II to the gene promoter. The most heavily regulated step is transcription initiation that involves the ordered assembly of Pol II, the general transcription factors (TF) -IIA, -IIB, -IID, -IIF, -IIE, -IIH and the co-activator Mediator complex. Mediator communicates between transcription regulators and Pol II, and is associated with human disease. Mediator from the yeast Saccharomyces cerevisiae (Sc) has a molecular mass of 1.4 megadaltons and contains 25-subunits that constitute a head, middle, tail and kinase module. The core of Mediator contains the head and middle modules that are essential for viability in Sc, and directly contact Pol II. Mediator co-operates with TFIIH, to assist assembly and stabilization of the transcription initiation complex and stimulate TFIIH kinase activity. Because of the large size and complexity of Mediator and the initiation machinery, the underlying mechanism remains poorly understood. In this work we studied the structure and function of Mediator head and middle modules, the structure of the reconstituted Pol II-core Mediator transcription initiation complex, and reveal mechanisms of transcription regulation. We report the crystal structure of the 6-subunit Schizosaccharomyces pombe Mediator head module at 3.4 Å resolution. The structure resembles the head of a crocodile and reveals eight elements that are part of three domains named neck, fixed jaw and movable jaw. The neck contains a spine, shoulder, arm and finger. The arm and essential shoulder elements contact the remainder of Mediator and Pol II. The head module jaws and central joint, important for transcription, also interact with Mediator and Pol II. The Sp head module structure is conserved and revises a 4.3 Å model of the Sc head module, explains known mutations, and provides an atomic model for one half of core Mediator. We further propose a model of the Mediator middle module based on protein crosslinking and mass spectrometry. To determine how Mediator regulates initiation, we prepared recombinant Sc core Mediator by co-expression of its 15 subunits in bacteria. Core Mediator is active in transcription assays and bound an in vitro reconstituted core initially transcribing complex (cITC) that contains Pol II, the general factors TFIIB, TBP, TFIIF, and promoter DNA. We determined the cryo-electron microscopy structure of the initially transcribing core initiation complex at 7.8 Å resolution. The structure reveals the arrangement of DNA, TBP, TFIIB, and TFIIF on the Pol II surface, the path of the complete DNA template strand and three TFIIF elements. The ‘charged helix’ and ‘arm’ of TFIIF subunit Tfg1, reach into the Pol II cleft and may stabilize open DNA. The linker region of TFIIF subunit Tfg2 extends between Pol II protrusion and TFIIB, and may stabilize TFIIB. The structure agrees with its human counterpart, and suggests a conserved architecture of the core initiation complex. Finally, we determined the cryo-electron microscopy architecture of the cITC-core Mediator complex at 9.7 Å resolution. Core Mediator binds Pol II at the Rpb4/Rbp7 stalk close to the carboxy-terminal domain (CTD). The Mediator head module contacts the Pol II dock and TFIIB ribbon and stabilizes the initiation complex. The Mediator middle module ‘plank’ domain touches the Pol II foot and may control polymerase conformation allosterically. The Med14 subunit bridges head and middle modules with a ‘beam’, and connects to the tail module that binds transcription activators located on upstream DNA. The ‘arm’ and ‘hook’ domains of core Mediator form part of a ‘cradle’ that may position CTD and the TFIIH kinase to stimulate Pol II phosphorylation. Taken together, our results provide a structural framework to unravel the role of Mediator in transcription initiation and determine mechanisms of gene regulation.

Steve, Birdman and TFG1 sit down together and talk Geek. We discuss retro TV, nostalgia, Tech, Microsoft, Films and more! So Thank you again to all who responded last week and we hope you join in the conversation this week as well. All this and more on this week’s AGU! We hope you continue to ...

Steve, Birdman and TFG1 sit down together and talk Geek. We discuss retro TV, nostalgia, Tech, Microsoft, Films and more! So Thank you again to all who responded last week and we hope you join in the conversation this week as well. All this and more on this week’s AGU! We hope you continue to enjoy ...

Steve, Mike and TFG1 sit down and chat about a variety of topics. We talk Beetlejuice sequel, New Pee-wee Herman Movie Produced By Judd Apatow Heading To Netflix, North Korea knocked offline, Unused Michael Keaton Batsuit Designs, is putting the “Throwback” 2003 Ninja Turtles episodes online, Peyton List To Play ‘Lisa Snart’, a.k.a. ‘The Golden ...

Steve, Mike and TFG1 sit down and chat about a variety of topics leading up to the last podcast of the year. Arrow, Flash, Continuum, Pirate Bay, AGU, Off The Cuff and future GCRN Projects were discussed. So Thank you again to all who responded last week and we hope you join in the conversation ...

Steve is joined by the 3 Mikes, TFG1, Birdman and Boothninja. We sit down and chat about Sony Hacks, Games, New Movie Trailers over the last week, the negativity surrounding the Star Wars trailer, Suicide Squad, Deadpool and more! We also jump into some weekly events, GCRN WarZ and a multitude of other topics. Thank ...

This week is a little less controversial. Sorry for some odd delays but plans for something new next week. We have Steve, TFG1 and Birdman Dodd this week talking Comics, Ghostbusters, Reboots and Geek Change. All this and more on this week’s AGU! We hope you continue to enjoy the episodes and please feel free ...

The guys fire up for a 2nd run at a live show. This week however, Steve and Mike and TFG1 will talk more of their things, as well as various news articles. We return to the 10 Minute Blitz and cover the feedback. All this and more on this week’s AGU! We hope you continue ...

Episode 01 of Pixels In The Animation is here!!! Join TFG1Mike and TV’s Mr. Neil as they tackle the first six episodes of The Super Mario Bros Super Show!!! Classic Gamers and Animation Aficionados alike should be listening to this podcast!!! Tune in to find out just what scars TFG1 for life, when it comes ...

This might be the most personal podcast series TFG1Mike has ever done. It is the first ever GCR spinoff series. Here the adventure of flying back hom to Boston, then driving back to Louisville. TFG1Mike introduces you to his mom Kathy.  Geeks: Mike “TFG1″ Blanchard Kathy “GeekMom” Blanchard Subscribe to us using iTunes or use ...

Today September 17, 2012 marks the 28th anniversary of the 1984 Transformers cartoon. On this day we announce that in the year of the 30th Anniversary The TFG1 Podcast will be reformatted! Yes that's right we'll be doing TFG1 right this time around. It will have an all new RSS feed entitled The TFg2 Podcast. ...

Today September 17, 2012 marks the 28th anniversary of the 1984 Transformers cartoon. On this day we announce that in the year of the 30th Anniversary The TFG1 Podcast will be reformatted! Yes that’s right we’ll be doing TFG1 right this time around. It will have an all new RSS feed entitled The TFg2 Podcast. ...

We have covered tons of stuff in the music spotlight. Mainstream, heavy metal, countdowns, artist spotlights, and more. In this ep Birdman, JT, and TFG1 talk about the lesser know stuff, covers, cover bands, and video game music. We also hit on nerdcore. So be prepared to take the non mainstream.  Birdman Wants You To ...

Canadian Rockers Nickelback have risen to stardom in the music industry. Starting out very RAW, and unpolished, since 1996 they have crafted their sound, and are now one of the biggest names in Rock. In this artist spotlight TFG1, Birdman, and JT analyze everything there is to find out about Chad Kroeger, Ryan Peake, Mike ...

Supplemental Episode 20.5: In the fourth of our Supplemental episodes, join Optimus and TFG1 as they talk about one of the key elements to any successful television show…the THEME SONG!! Each host has prepared his top ten list of theme songs from the season 1 slate of shows. Will your favorite theme song from season ...

Supplemental Episode 15.5: In the third of our Supplemental episodes, join Optimus, TFG1 and Glade as they discuss their top ten picks for their favorite Puppet characters of all-time. The lists were not limited to ‘muppet’ characters and the guys did come up with some creative puppets in their lists.  This show definitely does its ...

Supplemental Episode 10.5: In the second of our Supplemental episodes, join Optimus and TFG1 as they discuss their top ten picks for which 80s/90s kids show characters they would most want to have as their parent. Thats right who were the best adult role models, father/mother figures, or any other way you want to interpret ...

In this episode of The MWIRE the 2 Mikes review Daredevil where TFG1Mike points out the differences between the theatrical release DVD and the Directors Cut DVD. So join in the fun with Birdman and TFG1 as they give Daredevil good grades and kick the Elektra film in the ass. Geeks: Mike “TFG1″ Blanchard Mike …

Mike Celebrates the 20th episode of TFG1 with Michael and Steve/Megatron, a fun time is had by all Discussing Starscream's Ghost, Ghost In The Machine, and three other episodes that are just forgetable. The trio is cut to a duo after Steve has to leave, but still a awesome episode of The TFG1 Podcast. Guest ...

Mike Celebrates the 20th episode of TFG1 with Michael and Steve/Megatron, a fun time is had by all Discussing Starscream’s Ghost, Ghost In The Machine, and three other episodes that are just forgetable. The trio is cut to a duo after Steve has to leave, but still a awesome episode of The TFG1 Podcast. Guest ...

In the 11th episode TFG1 has been reformatted! Also this episode features the return of The Display Case Mike also reviews Kremzeek! and four more episodes from Generation 1 Season 2. Geeks: Mike “TFG1? Blanchard Subscribe to us using iTunes or use any other podcatching client by using: http://feeds.feedburner.com/TheTFG1Podcast Download TFG1_EP011.mp3

In the 11th episode TFG1 has been reformatted! Also this episode features the return of The Display Case Mike also reviews Kremzeek! and four more episodes from Generation 1 Season 2. Geeks: Mike “TFG1? Blanchard Subscribe to us using iTunes or use any other podcatching client by using: http://feeds.feedburner.com/TheTFG1Podcast Download TFG1_EP011.mp3

Geeks: Steve “Megatron” Phillips Mike “TFG1? Blanchard Subscribe to us using iTunes or use any other podcatching client by using: http://feeds.feedburner.com/AllThingsTransformersV3

The Now Lost Episode of TFG1 has finally been released. Geeks: Mike “TFG1? Blanchard Subscribe to us using iTunes or use any other podcatching client by using: http://feeds.feedburner.com/TheTFG1Podcast Download TFG1_EP003-SUPL.mp3

The Now Lost Episode of TFG1 has finally been released. Geeks: Mike “TFG1? Blanchard Subscribe to us using iTunes or use any other podcatching client by using: http://feeds.feedburner.com/TheTFG1Podcast Download TFG1_EP003-SUPL.mp3

Crossover of ATTF and TFG1. Best of 2008 Episode. Geeks: Steve “Megatron” Phillips Mike “TFG1? Blanchard Subscribe to us using iTunes or use any other podcatching client by using: http://feeds.feedburner.com/TheTFG1Podcast Download TFG1_EP002-SUPL.mp3

Crossover of ATTF and TFG1. Best of 2008 Episode. Geeks: Steve “Megatron” Phillips Mike “TFG1? Blanchard Subscribe to us using iTunes or use any other podcatching client by using: http://feeds.feedburner.com/TheTFG1Podcast Download TFG1_EP002-SUPL.mp3