Podcasts about berlex biosciences

There's plenty of controversy these days around telomere testing. Is it accurate? Does it really show your so-called "biological vs. chronological" age? And once you do get your results, how can you lengthen your telomeres? In today's episode, I interview one of the world's leading experts on telomeres: Dr. Bill Andrews. Dr. Andrews is the Founder and CEO of , a company focused on finding ways to extend the human lifespan and health span through telomere maintenance. As a scientist, athlete and executive, he continually pushes the envelope and challenges convention. He has been featured in Popular Science, The Today Show and numerous documentaries on the topic of life extension including, most recently, the movie The Immortalists in which he co-stars with Aubrey de Grey. Bill has been a researcher in biotech since 1981, focusing on cancer, heart disease, and inflammation research; though his passion has always been aging. In the early to mid 1990’s, while at Geron Corporation, Bill led the research to discover both the RNA and protein components of human telomerase. He was awarded 2nd place as "National Inventor of the Year" in 1997. Bill earned his Ph.D. in Molecular and Population Genetics at the University of Georgia in 1981. And then served as Senior Scientist at Armos Corporation and Codon Corporation, Director of Molecular Biology at Berlex Biosciences and at Geron Corporation, and Director of Technology Development at EOS Biosciences, before starting Sierra Sciences in 1999. Bill is also a named inventor on over 50+ US issued patents on telomerase and author of numerous scientific research studies published in peer reviewed scientific journals. Bill is also an avid ultra-marathon runner. He regularly competes in 50 and 100+ mile races often finishing at the top of his age group. These grueling races have taken him all over the world to race in some of the most extreme environments, from Death Valley to the Himalayas. His running is presently featured in the movie The High. During our discussion, you'll discover: -The differing effects of short vs. long distance running on telomere lengths...9:25 Not the length per se, but how you do it. If it quits being fun, it's time to quit. Consistent running actually decreases inflammation; inconsistent or sporadic running is problematic -What are telomeres, and their role in our physical mortality...13:15 Think of each chromosome in the body as a "shoelace"; the little caps on the end of the laces are the telomeres Telomere shortening results in declining health with aging Each time our cells divide, our telomeres get a bit shorter DNA and cell replication Cells can't replicate DNA all the way to the end Cells eventually "crash"; lose the ability to function It's possible to calculate the maximum lifespan of a human based on telomere shortening rates Attention anti-agers: you can't do it unless you can figure out how to prevent telomere shortening -How telomeres can be lengthened, and how to lower the rate by which they shorten...19:30 Telomeres are not shortened when reproductive cells replicate Telomerase prevents the shortening of telomeres Telomerase is too big to get into cells Senescent cell: a cell that has lost the ability to divide Shutting down senescent cells actually inhibits cancer cells "Chromosome rearrangement": a precursor to cancer Shortened telomeres hinders cancer treatments such as chemotherapy Keeping telomeres long is the best way to treat cancer should it enter the body -Telomere tests: do they work, and how accurate are they...35:10 Accuracy is extremely low in measuring biological age Best available is fluorescence in situ hybridization ; PCR, a popular means of testing, is "manipulatable"- uncontrollable changes Test yourself multiple times; use different names Telomere Restriction Fragment is Dr. Andrews favorite test Difference in costs: More accurate = more expensive Range: $100-300 -The research Dr. Andrews is conducting on increasing telomerase activity...44:20 Two ways to produce telomerase inside the cells Find a way to turn the gene "on" in preexisting cells Deliver a brand new gene to the cell; turned on more than a regular gene Decreasing the rate of shortening the telomeres "Tug of War" analogy Not currently possible to reverse the aging process 1-3 years away from having the tug of war a "tie"; meaning the aging process comes to a halt, then possibly we'll see aging process reversed Real life products in the marketplace based on Dr. Andrews' research at Sierra Science...50:30 Dr. Andrews focuses solely on research; partners with pharmaceutical companies for marketing, distribution, etc. : a supplement that increases telomerase levels Dr. Andrews takes every supplement that's been shown to increase telomerase levels -Dr. Andrews' personal anti-aging protocol...53:45 You can't design natural products to be better; they would cease to be natural products Elements of his protocol that may fly under the radar: Omega 3 fatty acids () Yellow bell peppers: highest amount of Vitamin C and lowest amount of sugars Book: Yoga, meditation, running, don't increase telomerase, but limit shortening of telomeres -Precautions to take before diving headlong into an anti-aging protocol...1:07:35 No known negative effects of long telomeres Gene delivery/therapy -About the "telomere clock"...1:16:15 -And much more! Resources from this episode: - - - - - - - -Book: - - - - - - Episode sponsors: - Support for normal blood sugar levels and healthy energy metabolism, even after large, carb-rich meals. - After using the Joovv for close to 2 years, it's the only light therapy device I'd ever recommend. Give it a try: you won't be disappointed. Use my link for your purchase and score a sweet bonus gift! - Your Favorite Organic Foods and Products. Up to 50% Off. Delivered to Your Door. Use my link and get an extra 25% off your first order. - Wake up each day feeling rested. Relax your body after a long day. Help stiff joints feel young again. Use discount code "greenfield" and get 20% off your entire order!   Do you have questions, thoughts or feedback for Dr. Andrews or me? Leave your comments at http://bengreenfieldfitness.com/telomeres and one of us will reply!  

She works with individuals and organizations, consulting with them on how to develop a strategic business and life plan that will result in higher performance, increased productivity, and greater fulfillment.She holds a Master’s degree in Business from the Massachusetts Institute of Technology and was a marketing executive with Bristol-Meyer’s Squibb and Berlex Biosciences, as well as a Wealth Advisor with Morgan Stanley.She was CEO of her own firm, The Mendel Group, for seven years, helping to close funding (including IPO’s) and business development deals for Venture-Funded Start-Up firms backed by Kleiner Perkins, Senmed Ventures, Blue Cross Blue Shield and many others. Her firm worked with Senior Executives on critical projects at Fortune 500 firms such as Glaxo Smithkline and Pfizer.Her firm also published five books for the Biopharmaceutical Industry.She has been featured on NPR, The San Jose Business Journal, and the San Francisco Business Journal. Eileen is here today to share with us how you can live more passionately and abundantly by becoming empowered with practical tools to guide your business and life!Learn More: www.thebalancedmillionaire.comInfluential Influencers with Mike Saundershttp://businessinnovatorsradio.com/influential-entrepreneurs-with-mike-saunders/

She works with individuals and organizations, consulting with them on how to develop a strategic business and life plan that will result in higher performance, increased productivity, and greater fulfillment.She holds a Master’s degree in Business from the Massachusetts Institute of Technology and was a marketing executive with Bristol-Meyer’s Squibb and Berlex Biosciences, as well as a Wealth Advisor with Morgan Stanley.She was CEO of her own firm, The Mendel Group, for seven years, helping to close funding (including IPO’s) and business development deals for Venture-Funded Start-Up firms backed by Kleiner Perkins, Senmed Ventures, Blue Cross Blue Shield and many others. Her firm worked with Senior Executives on critical projects at Fortune 500 firms such as Glaxo Smithkline and Pfizer.Her firm also published five books for the Biopharmaceutical Industry.She has been featured on NPR, The San Jose Business Journal, and the San Francisco Business Journal. Eileen is here today to share with us how you can live more passionately and abundantly by becoming empowered with practical tools to guide your business and life!Learn More: www.thebalancedmillionaire.comInfluential Influencers with Mike Saundershttp://businessinnovatorsradio.com/influential-entrepreneurs-with-mike-saunders/

ON TODAY’S COUCHTALK WE WILL BE TALKING ABOUT “REVERSING AGING”… So excited to have as my guest today, Dr. Bill Andrews.  I’ve known Bill for almost a decade, and I’ve watched him really just push the envelope in so many areas of physical health, and in particular, relating to the science of maintaining healthy telomeres and literally reversing aging. For those who aren’t familiar with telomeres, they are the tips on every one of your body’s chromosomes.  Why Are Telomeres Important? Science has shown that our telomeres get shorter as we age. And they get shorter when we have a disease, are chronically stressed, etc! So clearly a better understanding of what will shorten and lengthen our telomeres is important to living longer…and living more healthily. What’s so interesting about our discussion during this awesome interview is the perspective between “slowing aging (or slowing decline in our health)” vs. “reversing aging”. We discuss the science behind telomeres and telomerase (an enzyme identified as having the ability to lengthen telomeres) in an understandable way for such a complex area of science. This is definitely worth a thoughtful listen to and please post your questions. SOME KEY POINTS WE DISCUSSED: Telomeres really are the “end of life clock that is ticking inside all of us”… Science has proven telomeres are shortened every time cells divide (Bill explains why in our interview), so diseases and lifestyle choices that cause greater cell division cause your telomeres to shorten more quickly! This includes chronic stress and anything that increases your inflammation! Pessimistic thought has been linked to shorter telomeres! Women who experience greater sexually intimacy – and who are in long-term, committed relationships – have longer telomeres! People having more oxytocin in their lives have longer telomeres! Mediation and yoga seem to result in longer telomeres! BILL’S BOTTOM LINE: Lifestyle choices can slow decline in your health (and can cause telomeres to shorten more slowly)…but there is no current solution to lengthen telomeres (aka: reverse aging). But Bill is working on this! Learn more by listening in to this fascinating interview. MORE ABOUT DR. BILL ANDREWS Dr. Bill Andrews is the president and CEO of Sierra Sciences. As a scientist, athlete, and executive, he continually pushes the envelope and challenges convention. He’s been featured in Popular Science, The Today Show, and numerous documentaries on the topic of life extension. In his 32-year biotech career, he’s focused in the last 20 years on finding ways to extend the human lifespan and health span. It’s not only enough to live a long life but to live a quality life. And that has been in his research on telomere maintenance. He’s going to talk to us all about what telomere is and the importance of that. As one of the principal discoverers of both the RNA and protein components of human telomerase, Dr. Andrews was awarded 2nd place as “National Inventor of the Year” in 1997. He earned his Ph.D. in Molecular and Population Genetics at the University of Georgia in 1981. He has served as Senior Scientist at Armos Corporation and Codon Corporation, Director of Molecular Biology at Berlex Biosciences and at Geron Corporation, and Director of Technology Development at EOS Biosciences. He is also a named inventor on 45 US issued patents on telomerase and author of numerous scientific research studies published in peer-reviewed scientific journals. He is also at age 65—did we say 65? He does a hundred-mile runs, finishing at the top of his age group. We’ll talk about that by doing grueling races including Death Valley races and races in the Himalayas. Learn more at http://www.sierrasci.com/ He also has a book, Telomere Basics: Curing Aging. I’ve included the link for it on Amazon (click on the photo), with a brief description if you are interested in more information. In the book… Bill Andrews explains the groundbreaking science of telomere biology, the first and only emergent technology that holds the promise of treating and reversing age-related diseases, including aging itself. Topics discussed include the biological basis for the human aging process, the basic science behind telomeres and telomerase, a history of Dr. Andrews’ discoveries at Sierra Sciences, the most exciting experiments demonstrating the promise of therapies based on telomere length maintenance, and the diseases that could be treated or cured by this technology. Dr. Andrews is the President and CEO of Sierra Sciences, a biotech company focused solely on reversing aging through telomere maintenance. He is one of the principal discoverers of both the RNA and protein components of human telomerase, the enzyme most critical to this technology. He has focused the last 20 years of his career exclusively on addressing the problem of human aging. All profits from the sale of this book go to anti-aging research.

ON TODAY'S COUCHTALK WE WILL BE TALKING ABOUT “REVERSING AGING”… So excited to have as my guest today, Dr. Bill Andrews.  I've known Bill for almost a decade, and I've watched him really just push the envelope in so many areas of physical health, and in particular, relating to the science of maintaining healthy telomeres and literally reversing aging. For those who aren't familiar with telomeres, they are the tips on every one of your body's chromosomes.  Why Are Telomeres Important? Science has shown that our telomeres get shorter as we age. And they get shorter when we have a disease, are chronically stressed, etc! So clearly a better understanding of what will shorten and lengthen our telomeres is important to living longer…and living more healthily. What's so interesting about our discussion during this awesome interview is the perspective between “slowing aging (or slowing decline in our health)” vs. “reversing aging”. We discuss the science behind telomeres and telomerase (an enzyme identified as having the ability to lengthen telomeres) in an understandable way for such a complex area of science. This is definitely worth a thoughtful listen to and please post your questions. SOME KEY POINTS WE DISCUSSED: Telomeres really are the “end of life clock that is ticking inside all of us”… Science has proven telomeres are shortened every time cells divide (Bill explains why in our interview), so diseases and lifestyle choices that cause greater cell division cause your telomeres to shorten more quickly! This includes chronic stress and anything that increases your inflammation! Pessimistic thought has been linked to shorter telomeres! Women who experience greater sexually intimacy – and who are in long-term, committed relationships – have longer telomeres! People having more oxytocin in their lives have longer telomeres! Mediation and yoga seem to result in longer telomeres! BILL'S BOTTOM LINE: Lifestyle choices can slow decline in your health (and can cause telomeres to shorten more slowly)…but there is no current solution to lengthen telomeres (aka: reverse aging). But Bill is working on this! Learn more by listening in to this fascinating interview. MORE ABOUT DR. BILL ANDREWS Dr. Bill Andrews is the president and CEO of Sierra Sciences. As a scientist, athlete, and executive, he continually pushes the envelope and challenges convention. He's been featured in Popular Science, The Today Show, and numerous documentaries on the topic of life extension. In his 32-year biotech career, he's focused in the last 20 years on finding ways to extend the human lifespan and health span. It's not only enough to live a long life but to live a quality life. And that has been in his research on telomere maintenance. He's going to talk to us all about what telomere is and the importance of that. As one of the principal discoverers of both the RNA and protein components of human telomerase, Dr. Andrews was awarded 2nd place as “National Inventor of the Year” in 1997. He earned his Ph.D. in Molecular and Population Genetics at the University of Georgia in 1981. He has served as Senior Scientist at Armos Corporation and Codon Corporation, Director of Molecular Biology at Berlex Biosciences and at Geron Corporation, and Director of Technology Development at EOS Biosciences. He is also a named inventor on 45 US issued patents on telomerase and author of numerous scientific research studies published in peer-reviewed scientific journals. He is also at age 65—did we say 65? He does a hundred-mile runs, finishing at the top of his age group. We'll talk about that by doing grueling races including Death Valley races and races in the Himalayas. Learn more at http://www.sierrasci.com/ He also has a book, Telomere Basics: Curing Aging. I've included the link for it on Amazon (click on the photo), with a brief description if you are interested in more information. In the book… Bill Andrews explains the groundbreaking science of telomere biology, the first and only emergent technology that holds the promise of treating and reversing age-related diseases, including aging itself. Topics discussed include the biological basis for the human aging process, the basic science behind telomeres and telomerase, a history of Dr. Andrews' discoveries at Sierra Sciences, the most exciting experiments demonstrating the promise of therapies based on telomere length maintenance, and the diseases that could be treated or cured by this technology. Dr. Andrews is the President and CEO of Sierra Sciences, a biotech company focused solely on reversing aging through telomere maintenance. He is one of the principal discoverers of both the RNA and protein components of human telomerase, the enzyme most critical to this technology. He has focused the last 20 years of his career exclusively on addressing the problem of human aging. All profits from the sale of this book go to anti-aging research.

I would like to introduce our guest speaker Eileen Mendel. Eileen is a Business Strategist, Social Media Expert, Life Mastery Consultant, Motivational Speaker and Author. She hosts her own podcast "The Balanced Millionaire." Eileen works with individuals and organizations, teaching them how to use transformational tools to develop a strategic business and life plan that will result in higher performance, increased productivity, and greater fulfillment. She holds a Master's degree in Business from the Massachusetts Institute of Technology and was a marketing executive with Bristol-Meyer's Squibb and Berlex Biosciences, as well as a Wealth Advisor with Morgan Stanley. She was CEO of her own firm, The Mendel Group, for seven years, helping to close funding (including IPO's) and business development deals for Venture-Funded Start-Up firms backed by Kleiner Perkins, Senmed Ventures, Blue Cross Blue Shield and many others. Her firm worked with Senior Executives on critical projects at Fortune 500 firms such as Glaxo Smithkiline and Pfizer. Her firm also published five books for the Biopharmaceutical Industry. She has been featured on NPR, The San Jose Business Journal, and the San Francisco Business Journal. Eileen is here today to share with us how you can live more passionately and abundantly by becoming empowered with practical tools to guide your business and life! I would like to introduce our guest speaker Eileen Mendel. Eileen is a Business Strategist, Life Mastery Consultant, Motivational Speaker and Author. She works with individuals and organizations, teaching them how to use transformational tools to develop a strategic business and life plan that will result in higher performance, increased productivity, and greater fulfillment. She holds a Master's degree in Business from the Massachusetts Institute of Technology and was a marketing executive with Bristol-Meyer's Squibb and Berlex Biosciences, as well as a Wealth Advisor with Morgan Stanley. She was CEO of her own firm, The Mendel Group, for seven years, helping to close funding (including IPO's) and business development deals for Venture-Funded Start-Up firms backed by Kleiner Perkins, Senmed Ventures, Blue Cross Blue Shield and many others. Her firm worked with Senior Executives on critical projects at Fortune 500 firms such as Glaxo Smithkiline and Pfizer. Her firm also published five books for the Biopharmaceutical Industry. She has been featured on NPR, The San Jose Business Journal, and the San Francisco Business Journal. Eileen is here today to share with us how you can live more passionately and abundantly by becoming empowered with practical tools to guide your business and life! --- Support this podcast: https://anchor.fm/authorsunite/support

We welcome back Dr. Bill Andrews of Sierra Sciences to further expand on research into telomeres and telomerase for extending lifespan. Dr. Andrews explains how the existing research shows that there are potential telomere lengtheners, but they are still losing the tug-of-war with telomere shortening. He talks about how lack of funding may be the primary obstacle for telomere breakthroughs. Dr. Andrews also explains the actual link between telomerase and cancer, which is often misunderstood. They also consider the implications of gene therapy and gene editing in terms of producing telomerase. The main cause of telomere shortening is a lack of telomerase, though some things accelerate the process, like oxidative stress and inflammation. The doctors list a number of things people can do to reduce oxidative stress, including lifestyle changes and supplements that can help. Learn more about products by defytime® here. For information on IsaGenesis®/Product B, visit here. Learn more about Life Length: https://lifelength.com/ Learn more about RAADfest. On This Week on Longevity Science, Robb Taylor talks about the potential of Vitamin C to help in cancer therapy. Read more on the blog. Ask yourself: How serious am I about altering my lifestyle to protect my telomere lengths, and how much of my life, thought process and financial resources should I devote to this?  Special Guest: Dr. Bill Andrews is the President and CEO of Sierra Sciences. As a scientist, athlete and executive, he continually pushes the envelope and challenges convention. He has been featured in Popular Science, The Today Show and numerous documentaries on the topic of life extension, including, most recently, the movie The Immortalists in which he co-stars with Aubrey de Grey. Since 1981, Bill Andrews has focused on finding ways to extend the human lifespan and healthspan through telomere maintenance. As one of the principal discoverers of both the RNA and protein components of human telomerase, Dr. Andrews was awarded 2nd place as "National Inventor of the Year" in 1997. He earned his Ph.D. in Molecular and Population Genetics at the University of Georgia in 1981. He has served as Senior Scientist at Armos Corporation and Codon Corporation, Director of Molecular Biology at Berlex Biosciences and at Geron Corporation, and Director of Technology Development at EOS Biosciences. He is also a named inventor on over 50+ US issued patents on telomerase and author of numerous scientific research studies published in peer reviewed scientific journals. Bill is also an avid ultra-marathon runner. Born December 10, 1951, he regularly competes in 100k and 100+ mile runs often finishing at the top of his age group. These grueling races have taken him all over the world to race in some of the most extreme environments, from Death Valley to the Himalayas. His running is presently featured in the movie The High. You can order his books Bill Andrews on Telomere Basics: Curing Aging and Telomere Lengthening: Curing All Disease Including Aging and Cancer now. Follow Sierra Sciences on Facebook and Twitter: @SierraSciences.    

On this episode, we’re featuring a special RAAD Fest discussion from last year between Dr. Gladden and Dr. Bill Andrews, one of the leading scientists in telomere research. Dr. Andrews explains how telomeres work and how the length impacts your life expectancy. Put simply, longer telomeres are always good, and the shortening of them is always associated with disease and cell death.  Dr. Andrews mentions the book, The Telomere Effect by Dr. Elizabeth Blackburn and Dr. Elissa Epel, regarding slowing the shortening of telomeres. They discuss the research into telomerase activators and the hope for working toward lengthening telomeres. He discusses TAM-818 and TA-65® as means to reduce the rate of telomere shortening and offers up his top three suggestions on what people can do to extend their lives.  Special Guest:  Dr. Bill Andrews is the President and CEO of Sierra Sciences. As a scientist, athlete and executive, he continually pushes the envelope and challenges convention. He has been featured in Popular Science, The Today Show and numerous documentaries on the topic of life extension, including, most recently, the movie The Immortalists in which he co-stars with Aubrey de Grey. Since 1981, Bill Andrews has focused on finding ways to extend the human lifespan and healthspan through telomere maintenance. As one of the principal discoverers of both the RNA and protein components of human telomerase, Dr. Andrews was awarded 2nd place as "National Inventor of the Year" in 1997. He earned his Ph.D. in Molecular and Population Genetics at the University of Georgia in 1981. He has served as Senior Scientist at Armos Corporation and Codon Corporation, Director of Molecular Biology at Berlex Biosciences and at Geron Corporation, and Director of Technology Development at EOS Biosciences. He is also a named inventor on over 50+ US issued patents on telomerase and author of numerous scientific research studies published in peer reviewed scientific journals.  Bill is also an avid ultra-marathon runner. Born December 10, 1951, he regularly competes in 100k and 100+ mile runs often finishing at the top of his age group. These grueling races have taken him all over the world to race in some of the most extreme environments, from Death Valley to the Himalayas. His running is presently featured in the movie The High. You can order his books Bill Andrews on Telomere Basics: Curing Aging and Telomere Lengthening: Curing All Disease Including Aging and Cancer now.