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In the late 1990s, a strange carbon molecule quietly delivered the single longest lifespan extension ever recorded in mammals. The rats lived about 90% longer, and almost no one was paying attention. This episode breaks down what that molecule is, why it works, and how it may upgrade mitochondria, sleep, and human performance when used correctly. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Chris Burres, founder and chief scientist of MyVitalC and the original long-term manufacturer of carbon 60. Chris has produced this Nobel Prize–winning molecule since the early 1990s, supplying research institutions around the world years before it ever entered the biohacking space. He explains how carbon 60 behaves differently from traditional antioxidants, why stability and concentration used to be major problems, and how modern manufacturing finally made real-world use possible. Chris is also a published author, longevity summit host, patent holder, and longtime science communicator who brings rare clarity and humor to complex biology. Dave and Chris explore how carbon 60 interacts with mitochondria, oxidative stress, metabolism, and electrical signaling in the body, and where it fits alongside ketosis, nootropics, supplements, and functional medicine strategies. They also unpack why improving mitochondrial function often shows up first as better energy and sleep optimization, and how that foundation supports longevity, brain optimization, and Smarter Not Harder performance. Along the way, Dave shares his own early experience with C60, how he uses it today, and why it now shows up even in his Danger Coffee stack. You'll Learn: • Why carbon 60 produced the longest longevity result ever recorded in mammal studies • How mitochondrial efficiency shapes energy, sleep, and human performance • What makes C60 a selective antioxidant instead of a blunt one • Why purity, concentration, and stability determine whether a supplement works • How carbon 60 fits into biohacking stacks built around ketosis and metabolism • What users report first, from focus and resilience to deeper sleep • Why mitochondrial health underpins long-term anti-aging strategies • How to think about supplements through a Smarter Not Harder lens Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Affiliates: Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: carbon 60 podcast, C60 longevity science, biohacking mitochondria, mitochondrial optimization podcast, anti-aging supplements science, human performance longevity, selective antioxidant mitochondria, sleep optimization biohacking, brain optimization supplements, nootropics longevity stack, ketosis metabolism longevity, functional medicine mitochondria, oxidative stress longevity, carbon 60 supplement science, MyVitalC podcast, Chris Burres interview, Dave Asprey biohacking, Danger Coffee stack, Smarter Not Harder longevity, Nobel Prize molecule longevity, mitochondrial health podcast Resources: • Get a 30% discount on your next purchase of ESS60 at: https://www.myvitalc.com/pages/humanupgradeod?ref=humanupgrade • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Introduction & C60 Discovery 4:04 – The Molecule & Nobel Prize 8:27 – Quantum Properties & Superconductivity 11:16 – Rat Longevity Study Results 14:33 – Selective Antioxidant Properties 15:51 – User Experience & Timeline 18:15 – Biological Age Testing 21:33 – Why Oil & Product Development 23:32 – Mechanism of Action 28:13 – Biohacker Discovery Story 30:03 – FDA & Supplement Regulation 33:50 – Migraines & Clinical Observations 37:53 – Athletic Performance 40:43 – Stacking & Contraindications 45:57 – Skincare Product 50:43 – Who Benefits Most 1:00:37 – Mitochondria & Consciousness 1:02:03 – Where to Buy & Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Nutritionist Leyla Muedin discusses the importance of maintaining muscle mass during weight loss, highlighting recent research on the benefits of krill oil. Leyla delves into various aspects of the study conducted by Glasgow University's School of Human Nutrition, which demonstrated that daily supplementation with krill oil helps minimize muscle loss despite significant weight loss. The episode covers study details, the impact of krill oil on inflammation, muscle maintenance, and the potential advantages of krill oil over traditional fish oil. Leyla also emphasizes the critical role of a balanced diet and strength training in preserving muscle mass during weight loss journeys.
Anecdote on Heart Rate VariabilityWill there soon be biological criteria for diagnosing clinical depression?What is your opinion on cardioversion for curing atrial fibrillation?What's with the ongoing battle between low fat and full fat dairy advocates?What is the optimal blood level of folate?
Fish oil linked to reduced risk of atrial fibrillationIs it safe to take hydrogen peroxide every day over the long term?I've been experiencing arthritis and leg cramps during the night. What should I take?I follow a low-carb diet. Why is my Hemoglobin A1c high?
Helen Bennett, counsellor and psychotherapist, explores hormone-aware therapy practices and how hormonal shifts can influence neurodivergent presentations in clients assigned female at birth, with a focus on reducing distress, improving clinical understanding, and avoiding misdiagnosis. Interview with Elizabeth Irias, LMFT. Earn CE credit for listening to this episode by joining our low-cost membership for unlimited podcast CE credits for an entire year, with some of the strongest CE approvals in the country (APA, NBCC, ASWB, and more). Learn, grow, and shine with Clearly Clinical Continuing Ed by visiting https://ClearlyClinical.com.
Dr. Hoffman continues his conversation with Dr. Elena Gross, an expert on migraines and brain metabolism. She is the founder and CEO of KetoSwiss and MigraKet, is a passionate neuroscientist, has a PhD in clinical research, and is a former chronic migraine sufferer.
Unraveling Migraines with Dr. Elena Gross, an expert on migraines and brain metabolism. She is the founder and CEO of KetoSwiss and MigraKet, is a passionate neuroscientist, has a PhD in clinical research, and is a former chronic migraine sufferer. Dr. Gross discusses her personal journey with chronic migraines and how it led her to develop innovative, natural approaches to migraine relief. She does a deep-dive into the nuances of brain energy, metabolism, oxidative stress, and the role of ketone bodies. Dr. Gross highlights her product line 'Brain Ritual' and how it can support brain health and tackle migraine symptoms. She also touches on the broader implications of these approaches for various neurodegenerative and psychiatric conditions. The discussion aims to offer practical solutions and a holistic understanding of brain health.Click here for $30 off your purchase of Brain Ritual.
You can ALWAYS get stronger, no matter your age. In this episode, I'm joined by muscle-centric medicine expert Dr. Gabrielle Lyon to reframe how you think about your health—starting with muscle. Life gets busy and chaotic, especially when you're juggling kids, work, and everything in between. So Dr. Lyon breaks down how to simplify your focus and double down on what truly moves the needle for your health. At the center of it all? Skeletal muscle– the key driver of metabolic health, strength, and resilience as we age. She explains why protecting and building muscle isn't about aesthetics—it's about safeguarding your heart, brain, and long-term vitality. We're here to remind you that strength training is really about training for your future self, and it can be easier than you may think. Ready to boost your strength and confidence in midlife? This is an episode you don't want to miss!
Optimizing Skin Health: Gut Microbiome, Probiotics, and Natural Remedies with Dr. Ross Pelton, The Natural Pharmacist and Director of Science & Education for Essential Formulas, which specializes in premium probiotic products. He discusses various methods to enhance skin health, focusing on the role of the gut microbiome, diet, and probiotics. He explores the concept of the gut-skin axis and how intestinal health impacts skin conditions like acne, eczema, and psoriasis. Dr. Pelton highlights specific probiotic products and postbiotic metabolites, explaining their benefits for both gut and skin health. The conversation also touches on lifestyle factors such as hydration, sleep, and exercise, discussing how they contribute to overall skin wellness. Additionally, he delves into the potential anti-aging effects of rapamycin and the importance of maintaining a diverse diet to support a healthy microbiome.
Dr. Hoffman continues his conversation with Dr. Ross Pelton, The Natural Pharmacist and Director of Science & Education for Essential Formulas, which specializes in premium probiotic products.
Press ballyhooed heart, stroke risks associated with Omega-3 supplementation, but new study dispels fears over fish oil-atrial fibrillation link; Research highlights cancer, diabetes risks from food preservatives; Do the new dietary guidelines go too far, or are they a cop-out? GLP-1 weight loss drug use could save airlines millions on fuel costs; Does a “complex tear” of the hip labrum inevitably require surgery?
Can we crack the code on aging, or are humans just “term-limited”? What are some of the most promising anti-aging interventions currently under investigation? We may be curing more cancers, and discovering them earlier, but certain cancers are increasing in incidence, especially among the young; Why extreme old age may be protective against cancer; Big meta-analysis confirms cardio benefits of low-carb diet; Patients with depression who've tried everything obtain surprising relief from vagus nerve stimulation; Blood sugar spikes after meals—even absent diabetes—can drive Alzheimer's risk; New study pushes back on Tylenol-autism link, but highlights poor diet, chemical exposure , pre-natal anti-depressant use as potential culprits.
From Creative License comes a new production of the recent Broadway hit “The Lifespan of a Fact.” Based on the true story of the essayist John D'Agata's essay "What Happens There," this funny and high-stakes debate over the boundary between truth and accuracy is helmed by Creative License co-founder Aaron Holbritter. The production features a cast of Capital Region talent, including Jacob Bell, Lisa Bryk, and Creative License favorite, Ian LaChance."The Lifespan of a Fact” will be performed at the Cohoes Music Hall in Cohoes, New York from January 30 through February 8.
In this deeply meaningful return conversation, Joni sits down again with spiritual mentor, energy alchemist, and author Liane Lambert to explore conscious parenting across the lifespan—from raising children with awareness, to healing our own childhood wounds, to navigating relationships with aging parents. Together, they unpack how to parent without control, guilt, or fear, how to break intergenerational patterns, and how to relate to children (and parents) as sovereign beings rather than projections of our own unresolved stories. This episode is for parents, grandparents, adult children, and anyone committed to living awake, aligned, and emotionally free. In this episode, you'll explore: What conscious parenting really means (and what it doesn't) Why removing the need to be "right" transforms relationships How to teach children emotional awareness without control Parenting teenagers without power struggles Healing trauma while raising children Navigating co-parenting, divorce, and misaligned relationships How to pause instead of react (and why that pause changes everything) Social media, AI, and raising kids who can think for themselves Boundaries vs. cutting people off—when each is necessary Relating to aging parents with compassion instead of control Letting go of guilt, obligation, and fear-based parenting Living from dharma rather than duty Guest Bio Liane Lambert is a spiritual mentor, energy alchemist, speaker, and author of Karma to Dharma: A New Age Guide to Becoming Superhuman. Her work bridges ancient wisdom with modern embodied spirituality, helping individuals and families heal ancestral patterns, activate soul purpose, and live aligned with their highest dharma. Work With Liane Liane's 9-week live course begins March 1st and is now open for registration.
Stephen Grootes speaks to Peter Armitage, CEO of Anchor Capital; Cobus Loots, CEO of Pan African; and Sithembile Bopela, an investment research analyst at FNB Wealth and Investments, about gold smashing through the $5 000 mark for the first time and what this historic surge signals for the global economy, investor sentiment and geopolitical risk. In other interviews, Cathrine Mushi, Councillor at ICASA and chairperson of the committee on End User Subscriber Charter talks about the new Icasa regulations on mobile data rollover and how they will affect consumers. The Money Show is a podcast hosted by well-known journalist and radio presenter, Stephen Grootes. He explores the latest economic trends, business developments, investment opportunities, and personal finance strategies. Each episode features engaging conversations with top newsmakers, industry experts, financial advisors, entrepreneurs, and politicians, offering you thought-provoking insights to navigate the ever-changing financial landscape. Thank you for listening to a podcast from The Money Show Listen live Primedia+ weekdays from 18:00 and 20:00 (SA Time) to The Money Show with Stephen Grootes broadcast on 702 https://buff.ly/gk3y0Kj and CapeTalk https://buff.ly/NnFM3Nk For more from the show, go to https://buff.ly/7QpH0jY or find all the catch-up podcasts here https://buff.ly/PlhvUVe Subscribe to The Money Show Daily Newsletter and the Weekly Business Wrap here https://buff.ly/v5mfetc The Money Show is brought to you by Absa Follow us on social media 702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/CapeTalk 702 on YouTube: https://www.youtube.com/@radio702 CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/Radio702 See omnystudio.com/listener for privacy information.
SOFIA DIN, MD is a New York–based, board-certified family physician with over 25 years of medical expered from treating disease to proactively optimizing health, wellness, beauty, and longevity. An immigrant from Pakistan, Dr. Din completed her medical training twice—first in her home country and again in the United States—giving her a rare perspective that blendsEastern and Western approaches to medicine. Her work as a medical director and lead geriatrician reshaped her view of aging, leading her to conclude that aging gracefully and aging helplessly are mutually exclusive.Determined to give patients agency over their health, she retrained in aesthetic and anti-aging medicine, mastering the latest FDA-cleared technologies, medications, and integrative therapies. Author of "Do We Really Need Botox?", Dr. Din shares a holistic, sciencebacked framework for extending healthspan and beautyspan without excessivesurgery. Featured in major press, TV, and TEDx, she engages audiences with practical, empowering strategies to lift their bodies out of life's natural "pauses," maximize vitality, nd redefine beauty as an essential part of wellness. We talk about: We talk about:e x p e r t g u e s • How to lift your body out of its naturally programmed "pauses" (menopause, andropause) • The world's fastest anti-aging medicine • The relationship between your Lifespan, Healthspan & Beautyspan • Best antiaging supplements and where to get them. - How AI will be used in the very near future to improve the healthy experience.
Nutritionist Leyla Muedin discusses the important relationship between gut health and bone health. Leyla delves into the ways gastrointestinal disorders like Crohn's disease, ulcerative colitis, and irritable bowel syndrome can lead to osteoporosis and increased fracture risks. She explains how chronic inflammation, malabsorption, and dysbiosis are common underlying causes of bone loss. Leyla also reviews scientific studies on the link between the gut microbiome and bone mass, highlighting the potential of fecal microbiome transplants as future treatments for osteoporosis.
In this episode of The Jordan Syatt Podcast I speak with Solid Heaston (IG: @solidheaston) about his experience preparing for his first bodybuilding competition and the struggles he faced as he lost more and more body fat. Solid shares how this journey impacted his relationship with food and his mental health, highlighting the fine line between discipline and disordered eating.I hope you enjoy this episode and, if you do, please leave a review on iTunes (huge thank you to everyone who has written one so far).Finally, if you've been thinking about joining The Inner Circle but haven't yet... we have hundreds of home and bodyweight workouts for you and you can get them all: https://www.sfinnercircle.com/
I have neuropathy in both my feet and lower legs. Are there any natural supplements I can take for it?I purchased two containers of Flavamix. What is the ingredient Lucuma and why is it in their cocoa powder?What are your thoughts on the PSMA PET scan for detecting prostate cancer?What supplements do you recommend for prostate health?What are your thoughts on taking famotidine 2 to 3 times a day for GERD? Can you discuss the different creatine products?
"Wintering" - how to optimize your winter experienceWhat we're eating for dinnerAn overview of the Dietary Guidelines for AmericansWhat can I do to rectify any scar tissue in my throat from previous thyroid surgery?What can my son do or take to minimize scarring above his right cheek from a basketball game tussle?
Exploring the Future of Aging with Journalist William J. Cole, author of “The Big 100: Uncovering the Keys to Longevity." The discussion delves into the challenges and societal implications of increased lifespans, especially among baby boomers. They explore the interplay of genetics and lifestyle in achieving longevity, the role of positivity, and the looming financial and caregiving challenges due to an aging population. Cole emphasizes the importance of adapting society to accommodate this demographic shift and highlights the importance of sustainable and healthy aging practices.
Dr. Hoffman continues his conversation with Journalist William J. Cole, author of “The Big 100: Uncovering the Keys to Longevity."
What if the real question isn't just how to live longer, but why so many people are living longer and healthier lives on paper, yet feel depleted, inflamed, disconnected, or cognitively foggy in daily life?In this solo episode, Dr. Taz reframes what longevity really means and why healthy aging has far less to do with chasing more years and far more to do with protecting cellular health, vitality, and resilience across decades. She explains why humans are living longer than ever before, yet not necessarily living better, and how focusing only on disease management or biohacking trends misses the real drivers of aging.You'll learn why longevity is not defined by a number, but by biological age, health span, and cellular aging, and how inflammation, metabolic dysfunction, gut imbalance, nervous system stress, emotional disconnection, and loss of community quietly accelerate aging long before symptoms become diagnoses.This episode reframes longevity as a full body system, not a supplement stack or a protocol. One that integrates physical health, brain function, emotional regulation, spirituality, and community. When these systems fall out of sync, aging speeds up. When they are supported together, living longer becomes living with clarity, strength, and purpose.Dr. Taz shares: • What longevity actually means and why lifespan and health span are not the same • Why humans are living longer but not necessarily healthier • How cellular aging, inflammation, and metabolic stress drive chronic disease • Why diet quality, gut health, liver function, movement, sleep, and nervous system balance matter more than biohacking • How cognitive reserve, dopamine regulation, and emotional health protect the aging brain • Why community and spirituality are overlooked but essential pillars of healthy aging • Where peptides, hormones, and modern longevity tools fit and where they don't • How to build a longevity plan that is realistic, accessible, and sustainableWhether you're thinking about how to live longer, worried about aging faster than you should, or simply want to protect your health span as you move through midlife and beyond, this episode offers a grounded, integrative roadmap.Longevity is not about optimizing harder. It's about supporting the systems that keep you well, year after year.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)Chapters00:00 Longevity is not about more years00:50 Are humans really living longer01:49 The global aging reality03:31 Why aging became something to fear05:17 Aging on a spectrum, not a number06:07 The hidden disease burden of aging08:31 Cellular aging explained09:45 Why biohacking misses the foundation11:10 The five-body approach to longevity13:10 Community, emotion, and aging14:05 Diet, inflammation, and cellular health16:19 Medications, gut health, and aging16:49 Fasting, calories, and longevity18:52 What eating for longevity actually means19:39 Movement and aging well21:35 Sleep, repair, and brain health22:50 Dementia, cognitive reserve, and prevention24:20 Dopamine, emotion, and brain aging26:49 Spirituality, community, and vitality30:05 Peptides, hormones, and future medicine31:58 A new vision for positive aging32:48 Longevity is built day by day (00:00) - Longevity is not about more years (00:50) - Are humans really living longer (01:49) - The global aging reality (03:31) - Why aging became something to fear (05:17) - Aging on a spectrum, not a number (06:07) - The hidden disease burden of aging (08:31) - Cellular aging explained (09:45) - Why biohacking misses the foundation (11:10) - The five-body approach to longevity (13:10) - Community, emotion, and aging (14:05) - Diet, inflammation, and cellular health (16:19) - Medications, gut health, and aging (16:49) - Fasting, calories, and longevity (18:52) - What eating for longevity actually means (19:39) - Movement and aging well (21:35) - Sleep, repair, and brain health (22:50) - Dementia, cognitive reserve, and prevention (24:20) - Dopamine, emotion, and brain aging (26:49) - Spirituality, community, and vitality (30:05) - Peptides, hormones, and future medicine (31:58) - A new vision for positive aging (32:48) - Longevity is built day by day
Embracing a Holistic, Pain-Free Approach to Exercise with Dr. John Rusin, world-renowned strength coach, physical therapist, and injury prevention expert. He's author of "Pain-Free Performance: Move Better, Train Smarter, and Build an Unbreakable Body." John is the founder of the Pain-Free Performance Specialist Certification (PPSC), which has certified over 20,000 fitness and rehab professionals worldwide. He discusses the importance of a comprehensive approach to fitness, focusing on diet, sleep, mood, attitude, supplements, and, importantly, exercise. He emphasizes sustainable, pain-free strength training suitable for all ages and fitness levels. The conversation challenges the outdated 'no pain, no gain' philosophy and highlights the significance of balanced fitness, encompassing strength training, cardio, mobility, and athleticism for overall health and longevity. Practical advice on avoiding overtraining, incorporating HIIT intelligently, and the critical role of protein and creatine supplementation is provided. The episode encourages listeners to take actionable steps towards a lifelong commitment to fitness, emphasizing that the right movement practice can enhance both physical health and mental well-being.
Dr. Hoffman continues his conversation with Dr. John Rusin, world-renowned strength coach, physical therapist, and injury prevention expert. He's author of "Pain-Free Performance: Move Better, Train Smarter, and Build an Unbreakable Body."
Oprah's new book encourages followers to “free themselves” from “shame and blame” by accessing weight loss meds; Her claim “it's the obesity gene” is put to the test by twin studies; Study shows brain stimulation with external electronic headset produces weight loss rivaling shots, pills; Ultra-processed food ups daily calorie intake by 500; Breast-feeding moms gain less post-pregnancy weight; Solutions for Myelodysplastic Syndrome; Scientists find hidden weight gain trigger in soybean oil.
Calculators that assess your risk for heart disease miss the boat—half of actual heart attack victims were said to be at low-risk; Why an app could erroneously tell you that you should be taking a statin; New ways to fix a calcified aortic valve; Common amino acid may bust Alzheimer's plaque, Adequate sleep may trump healthy diet, exercise for longevity; Chinese vegetarians less likely than omnivores to surpass 100; Easily-gobbled “fast food” stokes total daily calorie intake; Common chemicals hike MS risk two-fold; Low-glutamate diet relieves migraines; Fish oil confers substantial stroke, heart attack protection to dialysis patients.
Challenges of GLP-1 Drugs and New Dietary Guidelines for Americans. Nutritionist Leyla Muedin discusses the recent findings on weight regain after stopping GLP-1 receptor agonists like OZEMPIC and Wegovy, based on a recent British Medical Journal editorial. The episode also highlights the Dietary Guidelines for Americans (2025-2030), which recommend focusing on real, nutrient-dense foods, prioritizing protein, and reducing highly processed foods. Leyla addresses the importance of maintaining healthy eating habits during and after using GLP-1 drugs to achieve long-term weight management and overall health.
A spoof on suggested nutrition guidelinesDoes nicotine destroy the spine? I can't seem to find Alpha Base with or without iron anymore. What do you recommend?
I'm an 88-year-old man with an irregular heart rate. Any suggestions to treat this?My PSA is on an upward trend since my last test. Should I stop taking testosterone?What can I take for essential tremors? I wake often during the night. What can I take to help me stay asleep?What are your thoughts on grounding mats, mattress covers, and sheets? Are they the real deal?
Embracing Winter: Strategies for Wellbeing with Dr. Kari Leibowitz, health psychologist and author of "How to Winter: Harness Your Mindset to Thrive on Cold, Dark, or Difficult Days." She explores how to push back against the notion of winter gloom and discusses the importance of mindset, cultural practices, and cognitive behavioral therapy in improving mental well-being during the winter months. Dr. Leibowitz shares insights from her experiences in Nordic countries and practical tips for maintaining a positive outlook, staying active, and embracing seasonal activities. She also covers the physiological and mental health benefits of practices such as cold water immersion and sauna use. This episode provides valuable advice for anyone looking to improve their winter wellness and overall resilience.
Dr. Hoffman continues his conversation with Dr. Kari Leibowitz, health psychologist and author of "How to Winter: Harness Your Mindset to Thrive on Cold, Dark, or Difficult Days," about winter survival strategies.
What does play therapy look like beyond childhood? In this episode, Lisa is joined by Tara McDonald and Karen O'Neill of PIP Solutions UK to explore how play therapy can support healing across the lifespan. Together, they discuss how play adapts from infancy through adulthood, the importance of creating safety around play for older clients, and the powerful role of symbolic repair in psychotherapy. This conversation invites clinicians to expand their understanding of play, embrace developmentally responsive approaches, and recognize the healing potential of play at any age. ✨ Tara and Karen will also be hosting Lisa for a 3-day in-person Introduction to Synergetic Play Therapy program in October 2026 in Solihull, UK. https://pipsolutions.co.uk/courses/an-introduction-to-synergetic-play-therapy/ Original Air Date: February 20, 2024 Podcast Resources: Synergetic Play Therapy Institute Synergetic Play Therapy Learning Website FREE Resources to support you on your play therapy journey Aggression in Play Therapy: A Neurobiological Approach to Integrating Intensity * If you enjoy this podcast, please give us a five-star rating and review on Apple Podcast, subscribe wherever you listen to podcasts, and invite your friends/fellow colleagues to join us.
Unlocking Mitochondrial Health: Exploring Urolithin A and Mitochondria-Boosting Supplements with Dr. Brad Currier, a senior scientist and manager of clinical trials at Timeline, a Swiss biotech company known for their product MitoPure. The conversation delves into a unique compound, Urolithin A, which is derived from pomegranates and identified as a key activator of mitophagy—the cellular process of recycling and rejuvenating damaged mitochondria. Dr. Currier elaborates on the significant health benefits of Urolithin A, including improved muscle strength, enhanced immune function, and its potential cognitive and anti-aging effects. The episode also covers topics such as the role of exercise and dietary protein in maintaining muscle health, the future potential of supplementary compounds like creatine, and highlights the newly introduced MitoPure gummies designed for convenient daily intake. Additionally, the discussion extends to the implications of mitochondrial function in various tissues, including skin and hair health.
Dr. Hoffman continues his conversation with Dr. Brad Currier, a senior scientist and manager of clinical trials at Timeline, a Swiss biotech company known for their product MitoPure.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter brings together his most up-to-date thinking on cardiorespiratory fitness into a single, practical guide designed to help listeners structure training for maximal impact on healthspan, lifespan, and long-term independence. He explains why cardiorespiratory fitness is one of the strongest modifiable predictors of longevity, clarifies what zone 2 training actually represents and how it differs from higher-intensity work, and addresses persistent confusion around exercise volume, intensity, and time constraints. The discussion covers how to measure and track progress in zone 2, VO₂ max targets and age-adjusted goals, planning for the marginal decade, and how to balance zone 2 with higher-intensity training across different weekly volumes. Peter also outlines how cardio training should be tailored for beginners, experienced trainees, and older adults, with special considerations for women and guidance on avoiding the most common cardio-training mistakes. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #79 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Rational for discussing cardiorespiratory fitness, zone 2, and VO₂ max despite having covered the topic extensively [2:30]; Why cardiorespiratory fitness and VO₂ max are powerful and modifiable predictors of all-cause mortality compared with other health metrics [7:30]; How age-related declines in VO₂ max constrain healthspan and everyday physical function [12:30]; The cardiorespiratory fitness triangle: how different training intensities contribute to building the aerobic base, the aerobic peak, and overall aerobic capacity [14:15]; The cellular mechanics of cardiorespiratory fitness: mitochondria, lactate, muscle fiber recruitment, and intensity thresholds [18:45]; The debate over whether zone 2 training has unique benefits or whether higher-intensity exercise alone is sufficient [27:15]; Balancing intensity and sustainability as training volume increases, and the important role of zone 2 training [32:15]; How to identify your zone 2 training intensity [34:45]; How to measure and track improvements in zone 2 fitness [40:00]; How to accurately measure VO₂ max: lab testing, field tests, and the limits of wearables [45:15]; How to set meaningful VO₂ max targets based on age, sex, long-term decline, and desired physical capabilities later in life [51:15]; How to structure and execute a zone 2 workout [59:45]; How strictly should zone 2 be maintained during a workout? [1:04:00]; How to design a VO₂ max training session: interval length, intensity, recovery, and progression strategies [1:07:00]; Why heart rate is not a reliable metric for titrating VO₂ max interval intensity [1:12:00]; Practical ways to monitor VO₂ max improvements [1:13:30]; How to balance zone 2 and VO₂ max training [1:15:30]; How to structure training for someone limited to 150 minutes per week of total exercise [1:19:00]; How to allocate 150 minutes per week of dedicated cardiorespiratory training between zone 2 and VO₂ max work [1:23:00]; How to structure training for someone with substantial available time who wants to maximize cardiorespiratory fitness [1:24:30]; Why spreading aerobic training across the week beats compressing volume into one session [1:26:15]; How beginners and metabolically unhealthy individuals should start cardiorespiratory training safely [1:28:00]; How "training age" determines the intensity and workload needed to continue improving cardiorespiratory fitness [1:31:15]; Why zone 2 training still matters for women (including postmenopausal women) [1:32:45]; How cardiorespiratory training should adapt with aging [1:35:45]; The most common mistakes people make when training cardiorespiratory fitness and how to avoid them [1:37:45]; How to break through a VO₂ max plateau [1:40:45]; The main takeaways about cardiorespiratory fitness and longevity [1:41:30]; Peter's carve out: oral hygiene and Peter's two-toothbrush system [1:43:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
Applauding a long-overdue change to the broken Food Pyramid; Vitamin C enhances skin health, protects against environmental pollutants; FDA green lights testosterone replacement; Does CoQ10 protect against statin muscle damage? The story of America's first vitamin pioneer; Millions of America's seniors take 8 or more prescription drugs simultaneously.
MAHA derailed by federal policies that allow harmful chemicals to proliferate; 25 years later, a study that exonerated glyphosate has been retracted due to undue influence from Monsanto; Judge blocks W. Virginia artificial food dye and additive ban; New refined criteria would raise US obesity rate to nearly 70%; FDA approves electrical stimulation headset as safe and effective for home-use to treat depression; Accidental toxic fume releases on planes cause long-term disability, deaths, in passengers and crew. “Digital pacifier” screen time for toddlers found to hike risk for adolescent focus problems, anxiety; Is just a little red wine every day bad for you?
Chris Duffin sits down with legendary molecular biologist and endurance athlete Dr. Bill Andrews, a man who truly walks the walk when it comes to resilience. In this episode, we explore Dr. Bill Andrews's remarkable pursuits as an ultramarathon runner—including competing in grueling events like the Death Valley Badwater 135 and high-altitude races in the Himalayas, defying what most believe possible for a 70-plus-year-old. Beyond his athletic feats, Dr. Bill Andrews shares his groundbreaking work on the human telomerase gene—an innovation that reshaped how we understand aging at the cellular level. Practical Longevity Tips You Can Use Today Dr. Bill Andrews doesn't just share science—he gives you actionable ways to slow down cellular aging and protect your longevity: The impact of lifestyle choices (yes, he discusses alcohol, stress, diet, and even meditation) Nature's defenses: antioxidants, anti-inflammatories, and a sneak peek into cutting-edge nutraceuticals like Telovital Debunking myths around anti-aging products and the best, science-backed tests to measure your cellular age Dive deeper! Learn more about Dr. Bill Andrews, his quest for immortality, and his favorite anti-aging supplements at Sierra Sciences: https://sierrasci.com/dr-bill-andrews/
Nutritionist Leyla Muedin discusses the crucial importance of Omega-3 fats, particularly emphasizing their role in mental and heart health. She highlights a recent UK Biobank study demonstrating that higher Omega-3 levels are linked to a significantly lower risk of self-harm and suicidal ideation. Additionally, another study in the Journal of the American Heart Association reveals that elevated Omega-3 levels correlate with a reduced risk of atrial fibrillation (AFib). Leyla underscores the necessity of a balanced diet rich in Omega-3 sources like fatty fish and grass-fed meats, arguing that these nutrients are crucial for optimal mental and heart health.
AJP-Heart and Circulatory Physiology has been championing women's health research for many years, and in 2021 launched a special call for papers, which later became a standing collection in the journal, that has amassed over 100 peer reviewed publications focused on women's cardiovascular health. In 2024 the American Physiological Society launched the Women's Health Research Initiative aimed at addressing critical scientific gaps underlying health conditions that uniquely impact women. In this episode, Dr. Jason Carter (Baylor College) interviews authors Jenna Stone (McMaster University), Dr. Maureen McDonald (McMaster University), and Dr. Kerrie Moreau (University of Colorado Anschutz Medical Campus) about their recent Review article published as part of the Women's Health Research Initiative. Stone et al. discuss how traditional cardiovascular disease risk factors have been historically misidentified in females, the importance of certain metrics such as arterial stiffness and vascular endothelial function, and how early risk indicators are impacted during premenopausal period, pregnancy, and menopause. Ready to learn more? Listen now. Jenna C. Stone, Margie H. Davenport, Kerrie L. Moreau, Kyra E. Pyke, Megan M. Wenner, Jennifer S. Williams, and Maureen J. MacDonald Endocrine enigmas: vascular health in females throughout the lifespan Am J Physiol Heart Circ Physiol, published November 11, 2025. DOI: 10.1152/ajpheart.00412.2025
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Dr. Hoffman continues his conversation with Dr. Heather Zwickey, Vice President of Research and Academic Excellence, Provost, and Professor of Immunology at the National University of Natural Medicine (NUNM).
Innovative Approaches to Parkinson's Disease with Dr. Heather Zwickey, Vice President of Research and Academic Excellence, Provost, and Professor of Immunology at the National University of Natural Medicine (NUNM), and author of "Eating Better for Parkinson's: A Nutritional Starter Guide." She delves into innovative treatments for Parkinson's disease, including the role of diet, particularly a ketogenic diet, and the impact of the gut microbiome. Dr. Zwickey shares her inspiration from NBA player Brian Grant's experience with Parkinson's and discusses her small study on the feasibility of a ketogenic diet, showing promising results. She also details other potential treatments like supplements, exercise, particularly boxing and dancing, environmental factors, and even cannabis. Dr. Zwickey highlights the importance of personalized approaches due to varying individual responses to treatments.
Understanding and Treating Complex Illnesses with Dr. Neil Nathan, author of “Toxic 2nd Edition: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities, and Chronic Environmental Illness.” Dr. Nathan shares his expertise on the multifaceted nature of chronic illnesses, which often defy simple categorization and may be misdiagnosed as psychiatric issues. The discussion covers the impact of environmental toxins, electromagnetic fields, and infections like Lyme disease and long COVID. Dr. Nathan also highlights the importance of understanding inflammation's complex pathways and offers suggestions for both elimination of root causes and restoration of immune system functionality. The episode provides insights into new diagnostic tools and treatment methodologies for persistent and intrusive health issues.
Dr. Hoffman continues his conversation with Dr. Neil Nathan, author of “Toxic 2nd Edition: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities, and Chronic Environmental Illness.”
Welcome to the latest episode of L.I.F.T.S, your bite‑sized dose of the Latest Industry Fitness Trends and Stories. In this episode of, hosts Matthew Januszek and Mohammed Iqbal sit down with Dr. Bill Andrews: molecular geneticist, inventor, and telomere pioneer to explore what actually causes human aging and whether it can be slowed, stopped, or even reversed. Key topics covered: What telomeres are and why they determine human lifespan. Why aging isn't random, but biologically programmed. The real relationship between telomeres and cancer. How exercise, inflammation, and lifestyle impact cellular aging. Why most anti-aging products fail scientific scrutiny. The role of telomerase in extending cellular life. What longevity influencers often get wrong. Practical habits that may slow biological aging.