Podcasts about lifespan

Calculators that assess your risk for heart disease miss the boat—half of actual heart attack victims were said to be at low-risk; Why an app could erroneously tell you that you should be taking a statin; New ways to fix a calcified aortic valve; Common amino acid may bust Alzheimer's plaque, Adequate sleep may trump healthy diet, exercise for longevity; Chinese vegetarians less likely than omnivores to surpass 100; Easily-gobbled “fast food” stokes total daily calorie intake; Common chemicals hike MS risk two-fold; Low-glutamate diet relieves migraines; Fish oil confers substantial stroke, heart attack protection to dialysis patients.

Oprah's new book encourages followers to “free themselves” from “shame and blame” by accessing weight loss meds; Her claim “it's the obesity gene” is put to the test by twin studies; Study shows brain stimulation with external electronic headset produces weight loss rivaling shots, pills; Ultra-processed food ups daily calorie intake by 500; Breast-feeding moms gain less post-pregnancy weight; Solutions for  Myelodysplastic Syndrome; Scientists find hidden weight gain trigger in soybean oil.

Challenges of GLP-1 Drugs and New Dietary Guidelines for Americans. Nutritionist Leyla Muedin discusses the recent findings on weight regain after stopping GLP-1 receptor agonists like OZEMPIC and Wegovy, based on a recent British Medical Journal editorial. The episode also highlights the Dietary Guidelines for Americans (2025-2030), which recommend focusing on real, nutrient-dense foods, prioritizing protein, and reducing highly processed foods. Leyla addresses the importance of maintaining healthy eating habits during and after using GLP-1 drugs to achieve long-term weight management and overall health.

I'm an 88-year-old man with an irregular heart rate.  Any suggestions to treat this?My PSA is on an upward trend since my last test. Should I stop taking testosterone?What can I take for essential tremors?  I wake often during the night.  What can I take to help me stay asleep?What are your thoughts on grounding mats, mattress covers, and sheets? Are they the real deal?

A spoof on suggested nutrition guidelinesDoes nicotine destroy the spine?  I can't seem to find Alpha Base with or without iron anymore. What do you recommend?

Dr. Hoffman continues his conversation with Dr. Kari Leibowitz, health psychologist and author of "How to Winter: Harness Your Mindset to Thrive on Cold, Dark, or Difficult Days," about winter survival strategies.

Embracing Winter: Strategies for Wellbeing with Dr. Kari Leibowitz, health psychologist and author of "How to Winter: Harness Your Mindset to Thrive on Cold, Dark, or Difficult Days." She explores how to push back against the notion of winter gloom and discusses the importance of mindset, cultural practices, and cognitive behavioral therapy in improving mental well-being during the winter months. Dr. Leibowitz shares insights from her experiences in Nordic countries and practical tips for maintaining a positive outlook, staying active, and embracing seasonal activities. She also covers the physiological and mental health benefits of practices such as cold water immersion and sauna use. This episode provides valuable advice for anyone looking to improve their winter wellness and overall resilience.

What does play therapy look like beyond childhood? In this episode, Lisa is joined by Tara McDonald and Karen O'Neill of PIP Solutions UK to explore how play therapy can support healing across the lifespan. Together, they discuss how play adapts from infancy through adulthood, the importance of creating safety around play for older clients, and the powerful role of symbolic repair in psychotherapy. This conversation invites clinicians to expand their understanding of play, embrace developmentally responsive approaches, and recognize the healing potential of play at any age. ✨ Tara and Karen will also be hosting Lisa for a 3-day in-person Introduction to Synergetic Play Therapy program in October 2026 in Solihull, UK. https://pipsolutions.co.uk/courses/an-introduction-to-synergetic-play-therapy/ Original Air Date: February 20, 2024 Podcast Resources:  Synergetic Play Therapy Institute Synergetic Play Therapy Learning Website FREE Resources to support you on your play therapy journey  Aggression in Play Therapy: A Neurobiological Approach to Integrating Intensity * If you enjoy this podcast, please give us a five-star rating and review on Apple Podcast, subscribe wherever you listen to podcasts, and invite your friends/fellow colleagues to join us.

Dr. Hoffman continues his conversation with Dr. Brad Currier, a senior scientist and manager of clinical trials at Timeline, a Swiss biotech company known for their product MitoPure.

Unlocking Mitochondrial Health: Exploring Urolithin A and Mitochondria-Boosting Supplements with Dr. Brad Currier, a senior scientist and manager of clinical trials at Timeline, a Swiss biotech company known for their product MitoPure. The conversation delves into a unique compound, Urolithin A, which is derived from pomegranates and identified as a key activator of mitophagy—the cellular process of recycling and rejuvenating damaged mitochondria. Dr. Currier elaborates on the significant health benefits of Urolithin A, including improved muscle strength, enhanced immune function, and its potential cognitive and anti-aging effects. The episode also covers topics such as the role of exercise and dietary protein in maintaining muscle health, the future potential of supplementary compounds like creatine, and highlights the newly introduced MitoPure gummies designed for convenient daily intake. Additionally, the discussion extends to the implications of mitochondrial function in various tissues, including skin and hair health.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter brings together his most up-to-date thinking on cardiorespiratory fitness into a single, practical guide designed to help listeners structure training for maximal impact on healthspan, lifespan, and long-term independence. He explains why cardiorespiratory fitness is one of the strongest modifiable predictors of longevity, clarifies what zone 2 training actually represents and how it differs from higher-intensity work, and addresses persistent confusion around exercise volume, intensity, and time constraints. The discussion covers how to measure and track progress in zone 2, VO₂ max targets and age-adjusted goals, planning for the marginal decade, and how to balance zone 2 with higher-intensity training across different weekly volumes. Peter also outlines how cardio training should be tailored for beginners, experienced trainees, and older adults, with special considerations for women and guidance on avoiding the most common cardio-training mistakes. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #79 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Rational for discussing cardiorespiratory fitness, zone 2, and VO₂ max despite having covered the topic extensively [2:30]; Why cardiorespiratory fitness and VO₂ max are powerful and modifiable predictors of all-cause mortality compared with other health metrics [7:30]; How age-related declines in VO₂ max constrain healthspan and everyday physical function [12:30]; The cardiorespiratory fitness triangle: how different training intensities contribute to building the aerobic base, the aerobic peak, and overall aerobic capacity [14:15]; The cellular mechanics of cardiorespiratory fitness: mitochondria, lactate, muscle fiber recruitment, and intensity thresholds [18:45]; The debate over whether zone 2 training has unique benefits or whether higher-intensity exercise alone is sufficient [27:15]; Balancing intensity and sustainability as training volume increases, and the important role of zone 2 training [32:15]; How to identify your zone 2 training intensity [34:45]; How to measure and track improvements in zone 2 fitness [40:00]; How to accurately measure VO₂ max: lab testing, field tests, and the limits of wearables [45:15]; How to set meaningful VO₂ max targets based on age, sex, long-term decline, and desired physical capabilities later in life [51:15]; How to structure and execute a zone 2 workout [59:45]; How strictly should zone 2 be maintained during a workout? [1:04:00]; How to design a VO₂ max training session: interval length, intensity, recovery, and progression strategies [1:07:00]; Why heart rate is not a reliable metric for titrating VO₂ max interval intensity [1:12:00]; Practical ways to monitor VO₂ max improvements [1:13:30]; How to balance zone 2 and VO₂ max training [1:15:30]; How to structure training for someone limited to 150 minutes per week of total exercise [1:19:00]; How to allocate 150 minutes per week of dedicated cardiorespiratory training between zone 2 and VO₂ max work [1:23:00]; How to structure training for someone with substantial available time who wants to maximize cardiorespiratory fitness [1:24:30]; Why spreading aerobic training across the week beats compressing volume into one session [1:26:15]; How beginners and metabolically unhealthy individuals should start cardiorespiratory training safely [1:28:00]; How "training age" determines the intensity and workload needed to continue improving cardiorespiratory fitness [1:31:15]; Why zone 2 training still matters for women (including postmenopausal women) [1:32:45]; How cardiorespiratory training should adapt with aging [1:35:45]; The most common mistakes people make when training cardiorespiratory fitness and how to avoid them [1:37:45]; How to break through a VO₂ max plateau [1:40:45]; The main takeaways about cardiorespiratory fitness and longevity [1:41:30]; Peter's carve out: oral hygiene and Peter's two-toothbrush system [1:43:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

MAHA derailed by federal policies that allow harmful chemicals to proliferate; 25 years later, a study that exonerated glyphosate has been retracted due to undue influence from Monsanto; Judge blocks W. Virginia artificial food dye and additive ban; New refined criteria would raise US obesity rate to nearly 70%; FDA approves electrical stimulation headset as safe and effective for home-use to treat depression; Accidental toxic fume releases on planes cause long-term disability, deaths, in passengers and crew. “Digital pacifier” screen time for toddlers found to hike risk for adolescent focus problems, anxiety; Is just a little red wine every day bad for you?

Applauding a long-overdue change to the broken Food Pyramid; Vitamin C enhances skin health, protects against environmental pollutants; FDA green lights testosterone replacement; Does CoQ10 protect against statin muscle damage? The story of America's first vitamin pioneer; Millions of America's seniors take 8 or more prescription drugs simultaneously. 

LifeSpan

Chris Duffin sits down with legendary molecular biologist and endurance athlete Dr. Bill Andrews, a man who truly walks the walk when it comes to resilience. In this episode, we explore Dr. Bill Andrews's remarkable pursuits as an ultramarathon runner—including competing in grueling events like the Death Valley Badwater 135 and high-altitude races in the Himalayas, defying what most believe possible for a 70-plus-year-old. Beyond his athletic feats, Dr. Bill Andrews shares his groundbreaking work on the human telomerase gene—an innovation that reshaped how we understand aging at the cellular level.   Practical Longevity Tips You Can Use Today Dr. Bill Andrews doesn't just share science—he gives you actionable ways to slow down cellular aging and protect your longevity: The impact of lifestyle choices (yes, he discusses alcohol, stress, diet, and even meditation) Nature's defenses: antioxidants, anti-inflammatories, and a sneak peek into cutting-edge nutraceuticals like Telovital Debunking myths around anti-aging products and the best, science-backed tests to measure your cellular age   Dive deeper! Learn more about Dr. Bill Andrews, his quest for immortality, and his favorite anti-aging supplements at Sierra Sciences: https://sierrasci.com/dr-bill-andrews/

Nutritionist Leyla Muedin discusses the crucial importance of Omega-3 fats, particularly emphasizing their role in mental and heart health. She highlights a recent UK Biobank study demonstrating that higher Omega-3 levels are linked to a significantly lower risk of self-harm and suicidal ideation. Additionally, another study in the Journal of the American Heart Association reveals that elevated Omega-3 levels correlate with a reduced risk of atrial fibrillation (AFib). Leyla underscores the necessity of a balanced diet rich in Omega-3 sources like fatty fish and grass-fed meats, arguing that these nutrients are crucial for optimal mental and heart health.

AJP-Heart and Circulatory Physiology has been championing women's health research for many years, and in 2021 launched a special call for papers, which later became a standing collection in the journal, that has amassed over 100 peer reviewed publications focused on women's cardiovascular health. In 2024 the American Physiological Society launched the Women's Health Research Initiative aimed at addressing critical scientific gaps underlying health conditions that uniquely impact women. In this episode, Dr. Jason Carter (Baylor College) interviews authors Jenna Stone (McMaster University), Dr. Maureen McDonald (McMaster University), and Dr. Kerrie Moreau (University of Colorado Anschutz Medical Campus) about their recent Review article published as part of the Women's Health Research Initiative. Stone et al. discuss how traditional cardiovascular disease risk factors have been historically misidentified in females, the importance of certain metrics such as arterial stiffness and vascular endothelial function, and how early risk indicators are impacted during premenopausal period, pregnancy, and menopause. Ready to learn more? Listen now.   Jenna C. Stone, Margie H. Davenport, Kerrie L. Moreau, Kyra E. Pyke, Megan M. Wenner, Jennifer S. Williams, and Maureen J. MacDonald Endocrine enigmas: vascular health in females throughout the lifespan Am J Physiol Heart Circ Physiol, published November 11, 2025. DOI: 10.1152/ajpheart.00412.2025

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete EBAC/CME information, and to apply for credit, please visit us at PeerView.com/JNR865. EBAC/CME credit will be available until 8 December 2026.Shielding Generations With Pneumococcal Vaccination Approaches Across the Lifespan In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete EBAC/CME information, and to apply for credit, please visit us at PeerView.com/JNR865. EBAC/CME credit will be available until 8 December 2026.Shielding Generations With Pneumococcal Vaccination Approaches Across the Lifespan In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc.Disclosure information is available at the beginning of the video presentation.

Could you discuss GABA for insomnia and sleep support?  Are there long-term health benefits?What impact does a cocktail of pharmaceutical drugs have on the microbiome?Can I take more than 2 daily doses of Dr. Ohira's probiotics?Which is the correct estrogen to take in HRT?  Estriol or estradiol?In light of the recent EPA proposal to double permissible formaldehyde emissions, how does this jibe with MAHA?

Top stories of 2025Does the use of statins lead to muscle loss?I have mitral valve prolapse with regurgitation. Should I increase my supplement dosages?

Dr. Hoffman continues his conversation with Dr. Heather Zwickey, Vice President of Research and Academic Excellence, Provost, and Professor of Immunology at the National University of Natural Medicine (NUNM).

Innovative Approaches to Parkinson's Disease with Dr. Heather Zwickey, Vice President of Research and Academic Excellence, Provost, and Professor of Immunology at the National University of Natural Medicine (NUNM), and author of "Eating Better for Parkinson's: A Nutritional Starter Guide." She delves into innovative treatments for Parkinson's disease, including the role of diet, particularly a ketogenic diet, and the impact of the gut microbiome. Dr. Zwickey shares her inspiration from NBA player Brian Grant's experience with Parkinson's and discusses her small study on the feasibility of a ketogenic diet, showing promising results. She also details other potential treatments like supplements, exercise, particularly boxing and dancing, environmental factors, and even cannabis. Dr. Zwickey highlights the importance of personalized approaches due to varying individual responses to treatments.

Dr. Hoffman continues his conversation with Dr. Neil Nathan, author of “Toxic 2nd Edition: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities, and Chronic Environmental Illness.”

Understanding and Treating Complex Illnesses with Dr. Neil Nathan, author of “Toxic 2nd Edition: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities, and Chronic Environmental Illness.” Dr. Nathan shares his expertise on the multifaceted nature of chronic illnesses, which often defy simple categorization and may be misdiagnosed as psychiatric issues. The discussion covers the impact of environmental toxins, electromagnetic fields, and infections like Lyme disease and long COVID. Dr. Nathan also highlights the importance of understanding inflammation's complex pathways and offers suggestions for both elimination of root causes and restoration of immune system functionality. The episode provides insights into new diagnostic tools and treatment methodologies for persistent and intrusive health issues.

Advancing longevity research is about honoring the value of life—and translating that respect into evidence-based prevention. If healthcare is judged by life expectancy + quality of life, longevity medicine may be one of the most meaningful metrics we can pursue: extending health span through early detection, validated biomarkers, and interventions that scale.This unforgettable Expert Panel from the 4th annual Medical Innovation Olympics (#MIO2025) convened all-star global leaders in Longevity and Preventive Medicine who separated hype from reality and outlined what it will take to bring longevity into mainstream care - rigorously, ethically, and accessibly.Topics include: breakthroughs (including epigenetic approaches pointing toward functional restoration of eyesight), biomarkers/endpoints as the “keystone” for faster trials, the TAME (Targeting Aging with Metformin) concept, and the role of standards, education, trust, and shared responsibility—keeping dignity central.Panelists:Dr. David Barzilai (Harvard Medical School; Geneva College of Longevity Science, GCLS) • Dr. Dominik Thor (President, GCLS) • Dr. Mishkat Shehata (Emirates Lifestyle & Longevity Medicine Society) • Keith Comito (Lifespan Research Institute) • Dr. Uma Senthilkumar (Three Five Revive)

As we head into 2026, many of us are thinking about goals: what to improve, what to let go of, and how to live better. But what if the real question isn't how long we live, but how well we live? In this episode, Dr. Holly Carling and Alicia shift the conversation from lifespan to healthspanL the number of years you live with vitality, independence, mental clarity, and joy. Dr. Carling explains why modern medicine has extended lifespan without protecting quality of life, and how inflammation, nutrition, stress, and mindset quietly determine how we age. You'll learn how acupuncture, real food, emotional resilience, and intentional thinking can slow decline, restore balance, and help you build a future where strength, clarity, and purpose last well into later decades. This episode is a powerful invitation to rethink your 2026 goals, not as resolutions, but as investments in your future self. In this episode: The difference between lifespan and healthspan and why it matters Why many people spend their final years managing illness instead of enjoying life How inflammation quietly accelerates aging The role of acupuncture in regulating inflammation, circulation, hormones, and stress Why nutrition at the cellular level shapes long-term vitality How mindset and emotional health directly influence aging Why purpose, joy, and curiosity protect brain and immune health How to reframe goals around vitality instead of restriction A simple framework: repair, restore, and reinforce   For full show notes, resources and links head to: https://vitalhealthcda.com/podcasts/ The Vital Health for You Podcast is for everyone. Get to know us more by connecting with us at our website or on our Facebook page.   *Disclaimer: The statements made in this episode about specific products have not been evaluated by the U.S. Food & Drug Administration and are not intended to diagnose, treat, cure or prevent disease. All information provided is for informational purposes only and is not intended as a substitute for advice from your physician or other healthcare professional.

Welcome to the latest episode of L.I.F.T.S, your bite‑sized dose of the Latest Industry Fitness Trends and Stories. In this episode of, hosts Matthew Januszek and Mohammed Iqbal sit down with Dr. Bill Andrews: molecular geneticist, inventor, and telomere pioneer to explore what actually causes human aging and whether it can be slowed, stopped, or even reversed. Key topics covered: What telomeres are and why they determine human lifespan. Why aging isn't random, but biologically programmed. The real relationship between telomeres and cancer. How exercise, inflammation, and lifestyle impact cellular aging. Why most anti-aging products fail scientific scrutiny. The role of telomerase in extending cellular life. What longevity influencers often get wrong. Practical habits that may slow biological aging.

Nutritionist Leyla Muedin discusses the renaming of fatty liver disease to metabolic dysfunction-associated steatotic liver disease (M-A-S-L-D) to reduce stigma and improve diagnosis. Dr. Mary Ella's efforts at the University of Chicago Medicine highlight how this change aids in better patient identification and treatment. Leyla emphasizes lifestyle changes like a low-carb diet to manage and reverse the disease. The episode also covers the prevalence of fake extra virgin olive oil (EVOO) on the market, ways to identify authentic olive oil, and the importance of choosing quality over mass-produced options.

Our bodies are designed to move. Staying active is vital for maintaining good health. Regular physical activity engages in various bodily functions that contribute to life-extending benefits.

Our bodies are designed to move. Staying active is vital for maintaining good health. Regular physical activity engages in various bodily functions that contribute to life-extending benefits.

Our bodies are designed to move. Staying active is vital for maintaining good health. Regular physical activity engages in various bodily functions that contribute to life-extending benefits.

Our bodies are designed to move. Staying active is vital for maintaining good health. Regular physical activity engages in various bodily functions that contribute to life-extending benefits.

What are your thoughts on Alpha-ketoglutarate for healthy aging?A treatment for warts?Am I destined to develop diabetes given my strong family history of diabetes and high blood pressure?

Consequences of weight loss with weight loss drugs...Enter myostatin inhibitor drugsMy latest HgbA1c is 5.9, and I'm doing everything right. What gives?I'm approaching 80. Could you discuss aging?

What do you think of thiamine as a treatment for Parkinson's?Is there a natural thyroid medicine you recommend that is not pork-derived?Please discuss the COVID-19 vaccine and cardiology issuesCan you help my granddaughter with guttate psoriasis?

Holiday Stress tops tax season stressWhat would Dr. Hoffman say?Is berberine truly efficacious?My doctor recommends I drink alcohol to reduce stress and improve circulation

What do you think of serrapeptase for reducing coronary plaque?We were told to get a TDAP vaccine or we wouldn't be able to see our new grandchild for 8 weeks!Do I have lupus?Which supplements tend to reduce negative effects of X-rays?

The Holiday Season in NYCPeanut allergies cause and effectWhich calcium supplements can I take if I'm allergic to cow protein?Can my husband take saw palmetto in lieu of his prostate medications?What do you think of traction to help bulging discs?What is your take on green powder supplements?

Nutritionist Leyla Muedin details key aspects of supplement use and addresses frequently asked questions. Topics include the importance of targeted supplementation, the rationale behind personalized dosages, best practices for starting new supplements, and managing common issues like nausea and bright yellow urine. Leyla also explains why some supplements may cause gastrointestinal discomfort and provides guidance on how to adjust dosages for optimal results. Emphasis is placed on the benefits of pharmaceutical-grade supplements available on Fullscript and the necessity of regular blood tests to fine-tune supplementation.

What are your thoughts on the efficacy of strontium for bone health?What to you think of HRT for bone health?I have aortic valve stenosis. Is there any alternative to surgery?I have dry eyes after cataract surgeryAre there any benefits to Deer Antler for increasing HGH?

For dark days, get some sun in your eyesThe misleading vegan diet twin studyA least favorite thing from one of our listeners

Dr. Hoffman continues his conversation with Dr. Jeffrey Bland, founder and president of the Personalized Lifestyle Medicine Institute and Big Bold Health.

Dr. Jeffrey Bland, founder and president of the Personalized Lifestyle Medicine Institute and Big Bold Health, discusses his significant influence on functional medicine and offers a deep dive into the history and benefits of fish oil, including its impact on cardiovascular health, inflammation, and immune system resilience. Dr. Bland elaborates on the necessity of balanced Omega-3 fatty acids, particularly EPA and DHA, and the unique benefits of cold-processed fish oils that retain natural nutrients. The conversation also touches on Big Bold Health's innovative approach to health through products like Omega-3 Rejuvenate and Himalayan Tartary Buckwheat, highlighting their roles in promoting immune health. The episode underscores the importance of sustainability and the dedication of farmers and fishermen in producing high-quality, health-supportive products.

Dr. Hoffman continues his conversation with Jeffrey Rose, a certified master hypnotherapist and advocate for the MAHA (Make America Healthy Again) Initiative.

The MAHA Initiative and Health Advocacy with Jeffrey Rose, a certified master hypnotherapist and advocate for the MAHA (Make America Healthy Again) Initiative. Jeffrey Rose discusses his involvement with RFK Jr. and the MAHA movement, which aims to advance public health and freedom of choice in medicine. The conversation highlights various health reforms, including the benefits of starting school later for teenagers, the focus on chronic disease prevention, and the potential for bipartisan support in improving public health policies. Additionally, the discussion covers Rose's professional work in hypnotherapy, emphasizing its effectiveness in treating insomnia, addiction recovery, and weight loss.

In this special holiday crossover episode from Harvard Business School's Climate Rising podcast, Professor Mike Toffel talks with ThredUp CEO James Reinhart about the company's mission to extend the life of apparel and reduce waste through resale. As thrifting becomes more popular and circular business models gain traction, Reinhart explains why ThredUp built a national logistics and tech platform, how it collaborates with big brands, and the growing role of AI and automation in the industry.

Most people don't actually want to live to 90 or 100. Not because they don't love life—but because they're afraid of what those extra years might look like. Loss of independence. Chronic pain. Medications. Watching their world slowly shrink. When people say, "I don't want to live that long," what they're really saying is, "I don't want to live like that."   In the first episode of this new Year series, Ted reframes the entire conversation around aging. Instead of asking how long you'll live, he asks a more important question: How well will you live? Ted talks about healthspan—the years you remain strong, mobile, mentally sharp, and independent—and explains why it matters far more than lifespan alone.   He also breaks down why so much age-related decline is driven by lifestyle, not genetics, why modern healthcare focuses on crisis instead of prevention, and which core pillars actually determine how you age.   If you want 2026 to be the year you stop fearing the future and start building a body—and a life—that lasts, this is where the conversation begins. Listen now!    You'll learn:  How metabolic dysfunction silently accelerates aging  The role of muscle, strength, and power in maintaining independence  Why cardiovascular fitness and VO₂ max are strong predictors of longevity  How visceral fat drives inflammation and chronic disease  Why weight loss alone doesn't fix metabolic health    What Ted discusses in this episode:   (00:00) Introduction  (02:00) The Reality of Aging and Healthcare  (04:38) The Longevity Masterclass: Healthspan vs. Lifespan  (14:32) The Importance of Metabolic Health  (17:12) Muscle Strength and Power: Your Aging Insurance Policy  (18:36) Heart Aging and VO2 Max  (19:50) Brain Aging and Lifestyle Factors  (21:45) Series Overview and Conclusion 

Popular media leverage weak study to criticize RFK Jr.'s rethink of standard recommendations for saturated fat avoidance; Poor quality plant-based diets hike cardio risk; A listener complains his lp(a) is going up with age despite his healthy diet, lifestyle; Scientists pinpoint cocoa ingredient that slows aging; Berry proanthocyanidins preserve brain power; Tattooing may promote inflammation, undermine immunity.