Study of genetic differences within and between populations including the study of adaptation, speciation, and population structure
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5 episodes with Population genetics
2 episodes with Population genetics
5 episodes with Population genetics
26 episodes with Population genetics
2 episodes with Population genetics
3 episodes with Population genetics
2 episodes with Population genetics
2 episodes with Population genetics
2 episodes with Population genetics
In this episode of Tiny Show and Tell Us, we discuss the differences between e-cigarettes (vapes) and far-less-studied dry herb vaporizers. Then we talk about some of the incredible evolutionary adaptations of populations of people living at high altitudes. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode, we review the high-yield topic of Population Genetics from the Biochemistry section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
Cristina and Anahi chat with Dr. Gonzalo Figueiro about his groundbreaking research in ancient DNA, kinship, and population genetics. Dr. Figueiro is a Professor of Biological Anthropology at the University of the Republic, Uruguay, and holds a PhD in Biological Sciences from the Basic Sciences Development Programme (PEDECIBA), Uruguay. His main research interests are the genetics of ancient and modern human populations and the bioarchaeology of prehistoric populations in Uruguay. He also reflects and writes on the ethics of working with DNA samples and human remains from the past. ------------------------------ Find the paper discussed in this episode: Figueiro, G. (2024). Simulating the effects of kinship and postmarital residence patterns on mitochondrial DNA diversity in mortuary contexts. American Journal of Biological Anthropology, e24910. ------------------------------ Contact Gonzalo via email: gonzalo.figueiro@fhce.edu.uy ------------------------------ Contact the Sausage of Science Podcast and Human Biology Association: Facebook: facebook.com/groups/humanbiologyassociation/, Website: humbio.org, Twitter: @HumBioAssoc Cristina Gildee, Co-host, SoS Co-Producer, HBA Junior Fellow Website: cristinagildee.org, E-mail: cgildee@uw.edu Anahi Ruderman, Co-host, SoS Co-Producer, HBA Junior Fellow E-mail: aniruderman@gmail.com Twitter:@ani_ruderman
On this episode of ID the Future from the vault, we bring you the second of three short interviews with MIT-trained physicist Dr. Lee Spetner. We were saddened to learn of the recent passing of Dr. Spetner at 91 years old, and we're sharing these conversations in tribute to his significant contributions to the evolution debate. Host Ira Berkowitz interviews Dr. Spetner in Jerusalem. Together they explore key arguments from Spetner's books Not by Chance and The Evolution Revolution. Here, Spetner takes on natural selection, discussing what it can and cannot do. He also explores aspects of population genetics and the constraints the Earth's history imposes on evolving new species. This is Part 2 of a three-part interview. Listen to Read More › Source
Dr. Doron Behar, MD, PhD is Founder & CEO of an end-to-end genetic platform company, Igentify ( https://www.igentify.com/ ), that provides a suite of digital tools designed to scale the provision of genomic medical services to more people worldwide, making it more accessible and actionable for clinicians, laboratories, and patients. Dr. Behar received his degrees from the Technion - Israel Institute of Technology. As an MD, he has dual specialization in Internal Medicine and Critical Care Medicine from Rambam Medical Center in Haifa, Israel. Dr. Behar's research areas of interest are across the broad range of evolutionary genomics, ancestry, phylogenetics, and translational genomics. He has been the leading author and co-author of numerous research papers in these areas. Dr. Behar is the former Chief Scientific Officer of Gene-by-Gene Ltd., a commercial genetic testing company. His expertise covers various aspects of mass genotyping, including regulation, privacy, genetic analysis, quality assurance, and more. Support the show
Unveil the enigmatic ties between Rajasthan and distant lands in this trivia-packed Episode ! From the exploits of Paan Singh Tomar to the fascinating history of the Tomar clan, embark on a journey through time and lineage. Explore the tantalizing theories linking Rajasthan's Chauhan kings to the Huns of Hungary, weaving a tale of shared heritage across continents. Delve into the world of genetics as we unravel the diverse origins of communities like the Jats and Rajputs, revealing the intricate tapestry of human ancestry. Till then Check out the other episodes, The strange Polish notion of Holocaust Envy - https://bit.ly/48zECZr The Oak Tree that chronicled Poland's Modern History - https://bit.ly/4b1PlO8 The suprising evolution of Polish food - https://bit.ly/48RUGWe The complicated legacy of Schindler's List - https://bit.ly/3vF9NEi The untold story of Holocaust heroism: 'Under the Eagle' Pharmacy - https://bit.ly/3vEtzzL Two Billion Euros and the Polish Temple of Memory - https://bit.ly/3HjkrmN You can check previous episodes of 'Podcasts from Nowhere' on https://bit.ly/4b3wOB8 You can reach out to our host Utsav on Instagram: @whywetravel42(https://www.instagram.com/whywetravel42 ) Do follow IVM Podcasts on social media. We are @IVMPodcasts on Facebook, Twitter, & Instagram. Do share the word with your folks! See omnystudio.com/listener for privacy information.
PopGroup is the beloved annual meeting of the Population Genetics group of the Genetics Society. This episode we hear from Mike Richie, lead organiser at this year's host organisation - the University of St Andrews, from plenary speaker Susan Johnston and from student prizewinner Diana Lobo. Hosted on Acast. See acast.com/privacy for more information.
Dr. Jenkins sits down with Matt Buehler, a Ph.D. Candidate studying indigo snake genetics. They begin with how Matt found himself working with indigo snakes and cover some interesting steps in his career including studying Sea Kraits. They start the discussion of indigo snake genetics by talking about what has already been done, including a study using mitochondrial data that showed there are two clades of Eastern Indigo Snakes and a second study showing that there is gene flow between the clades. They talk about Matt's research, including looking at population structure of indigo snakes and understanding the indigo snake genome. The results from all these studies are important for developing reintroduction strategies.Connect with Matt on his website.Connect with Chris on Facebook, Instagram or at The Orianne Society.Shop Snake Talk merch.
A Zionist account of history has it that, at some point in the past, the Jewish people were exiled from Judea and forced to settle across the world. This exile is believed to have taken place either as a consequence of the 1st and 2nd century revolts against the Romans, or as a result of the Arab Muslim conquest of the 7th century. The problem with this narrative is that it's highly unlikely to be true. Christian Aid Gaza Appeal: https://www.christianaid.org.uk/appeals/emergencies/middle-east-crisis-appeal Buy me a Coffee page: https://www.buymeacoffee.com/DSConsciousness To subscribe to the show: https://payhip.com/b/Sq0ZB Track: Walk it Off - Jae Ren Music provided by Verde Música Studio Watch: https://www.youtube.com/watch?v=S2l-97PH5R8 Notes For the majority of this episode I have drawn on The Invention of the Jewish People, by Shlomo Sand: https://tinyurl.com/4kykxhdj Population Genetics in Israel in the 1950s: The Unconscious Internalization of Ideology, by Nurit Kirsh https://philpapers.org/rec/KIRPGI For a rundown of the Khazarian Mafia conspiracy theory see: https://www.isdglobal.org/digital_dispatches/an-antisemitic-conspiracy-theory-is-being-shared-on-telegram-to-justify-russias-invasion-of-ukraine/ How the ADL brands any questioning of Jewish identity anti-Semitic: https://extremismterms.adl.org/glossary/khazars A Modest Proposal: All Palestinians Should Convert to Judaism, by Nadia Hijab: https://forward.com/opinion/386761/a-modest-proposal-all-palestinians-should-convert-to-judaism/ Palestinian requests for conversion rejected outright, official says, Times of Israel: https://www.timesofisrael.com/palestinian-requests-for-conversion-rejected-outright-official-says/ Huge Spike in Number of Israelis 'un-Jewed' by Chief Rabbinate in Past Two Years, Haaretz: https://tinyurl.com/5yryu53v For work challenging Sand see: Cassius Dio's figures for the demographic consequences of the Bar Kokhba War: Exaggeration or reliable account?, by Dvir Raviv and Chaim Ben David https://tinyurl.com/29we77n2 The Myth of the Khazar Conversion, by Shaul Stampfer: https://www.youtube.com/watch?v=PYbycYgjnSU
In the US, roughly 1 in 33 infants are born with a congenital disability, about 25% of which have an identified genetic cause. For the first time,, parents can use Orchid's whole genome sequencing to screen their embryos for these genetic variants and mitigate their baby's disease risk. Check out orchidhealth.com, and use code RAZIB when signing up to skip the waitlist. What is caste? This is a question many Americans have been asking since the publication of Isabel Wilkerson's Caste: The Origins of Our Discontents (an Oprah's Book Club selection). On this episode of Unsupervised Learning, Razib talks at length about the historical, cultural and genetic aspects of caste. He explains the genetic origins and impacts of the practice in the Indian subcontinent, and how that contrasts with “caste” in other societies like feudal Japan. Razib also explores how caste, a European-origin word, came to bracket a sociological phenomenon that includes two related concepts, varna and jati, and how the former is abstract while the latter is concrete. Caste in the Indian subcontinent has massive social and political implications. Razib talks about the demographics of caste, and how this is relevant to considerations of equity in a nation-state originally founded on socialistic principles. In the subcontinent, caste is not simply a Hindu phenomenon but extends to Muslims and Christians. And in a subcontinent of nearly 2 billion people, caste expresses itself in varied ways depending on region. Finally, Razib ponders the future of the institution. If diasporic communities like Mauritius and Guyana are any guide, caste has a dim future. With urban jati exogamy rates increasing constantly over the last generation, Razib predicts that in the 22nd century caste in the subcontinent will be viewed as a outmoded practice continued only by a few communities. Caste is a question that is relevant to both the past and the present, but the forces of modernization will eat away at its foundations going forward.
Virginie Courtier-OrgogozoBiodiversité et écosystèmes (2022-2023)Collège de FranceColloque - Integrating Evolutionary Genetics and Ecology : An Ancestral Balanced Inversion Polymorphism Confers Global AdaptationSince the pioneering work of Dobzhansky in the 1940s, many chromosomal inversions have been identified but how they contribute to adaptation remains poorly understood. In Drosophila melanogaster, the widespread inversion polymorphism In(3R)P is involved in climate adaptation, exhibiting non-neutral latitudinal clines on multiple continents. Here, I summarize new results suggesting that this chromosomal rearrangement represents a long-term (equilibrium) balanced polymorphism of ancestral African origin and that it harbors alleles that are maintained by balancing selection on several continents. Our findings indicate that In(3R)P spread out of its ancestral subtropical/tropical range and then become latitudinally along similar but independent climatic gradients, always being frequent in subtropical/tropical areas but rare or absent in temperate climates.Thomas Flatt is Full Professor of Evolutionary Biology and Head of the Department of Biology at the University of Fribourg, Switzerland. Thomas' research interests are the genomic basis of adaptation, population genetics, and the evolution life histories and aging, mainly using Drosophila as a model system. He received his M.Sc. from the University of Basel in 1999 (supervisor: Prof. Stephen Stearns), for work done at the University of Sydney with Prof. Richard Shine, and his Ph.D. from Fribourg in 2004 (supervisor: Prof. Tadeusz Kawecki). Between 2004 and 2008, he was a postdoctoral researcher at Brown University with Prof. Marc Tatar and a visiting postdoc with Prof. Neal Silverman at UMass Medical School, funded by fellowships from the Swiss National Science Foundation (SNSF) and the Roche Research Foundation. Prior to taking up his position in Fribourg in 2017, he was a SNSF Professor in the Department of Ecology and Evolution at Lausanne (2012-17), a Fellow at the Wissenschaftskolleg Berlin (2012), a faculty member of the Vienna Graduate School of Population Genetics and a tenured group leader at the Institute of Population Genetics in Vienna (2009-12). Between 2018 and 2021 he held a DFG Mercator Fellowship and Visiting Professorship at the University of Münster. He has been serving on numerous editorial, advisory and reviewing panels and, with Josefa Gonzalez (Barcelona), co-leads an international consortium of researchers, the European Drosophila Population Genomics Consortium (DrosEU). He currently serves as an elected member of the National Research Council, the scientific body of the Swiss National Science Foundation (SNSF).
Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Properties of Good Textbooks, published by niplav on May 7, 2023 on LessWrong. Heuristics for choosing/writing good textbooks (see also here): Has exercises Exercises are interspersed in the text, not in large chunks (better at the end of sections, not just at the end of chapters). Solutions are available but difficult to access (in a separate book, or on the web), this reduces the urge to look the solution up if one is stuck. Of varying difficulty (I like the approach Concrete Mathematics takes: everything from trivial applications to research questions). I like it when difficulty is indicated, but it's also okay when it's said clearly in the beginning that exercises are not marked for difficulty (making them mystery boxes). Takes many angles Has figures and illustrations. I don't think I've encountered a textbook with too many yet. (See Visual Complex Analysis for an example of doing this well.) Has many examples. I'm not sure yet about the advantage of recurring examples. Same point about amount as with figures. Includes code, if possible. It's cool if you tell me the equations for computing the likelihood ratio of a hypothesis & dataset, but it's even cooler if you give me some sample code I can use and extend along with it. Uses typography You can use boldface and italics and underlining for reading comprehension, example here. Use section headings and paragraphs liberally. Artificial Intelligence: A Modern Approach has one- to three-word side-notes describing the content of each paragraph. This is very good. Distinguish definitions, proofs, examples, case-studies, code, formulas &c. Dependencies Define terms before they are used. (This is not a joke. Population Genetics uses the term "substitution" on p. 32 without defining it, and exercise 12-1 from Naive Set Theory depends on the axiom of regularity, but the book doesn't define it.) If the book has pre-requisites beyond what a high-schooler knows, a good textbook lists those pre-requisites and textbooks that teach them. Indicators Multiple editions are an indicator for quality. Ditto for multiple authors. A conversational and whimsy style can be nice, but shouldn't be overdone. Hot take: I get very little value from proofs in math textbooks, and consider them usually unnecessary (unless they teach a new proof method). I like the Infinite Napkin for its approach. Wishlist Flashcard sets that come together with textbooks. Please. 3blue1brown style videos that accompany the book. From Zero to Geo is a great step in that direction. Thanks for listening. To help us out with The Nonlinear Library or to learn more, please visit nonlinear.org.
Link to original articleWelcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Properties of Good Textbooks, published by niplav on May 7, 2023 on LessWrong. Heuristics for choosing/writing good textbooks (see also here): Has exercises Exercises are interspersed in the text, not in large chunks (better at the end of sections, not just at the end of chapters). Solutions are available but difficult to access (in a separate book, or on the web), this reduces the urge to look the solution up if one is stuck. Of varying difficulty (I like the approach Concrete Mathematics takes: everything from trivial applications to research questions). I like it when difficulty is indicated, but it's also okay when it's said clearly in the beginning that exercises are not marked for difficulty (making them mystery boxes). Takes many angles Has figures and illustrations. I don't think I've encountered a textbook with too many yet. (See Visual Complex Analysis for an example of doing this well.) Has many examples. I'm not sure yet about the advantage of recurring examples. Same point about amount as with figures. Includes code, if possible. It's cool if you tell me the equations for computing the likelihood ratio of a hypothesis & dataset, but it's even cooler if you give me some sample code I can use and extend along with it. Uses typography You can use boldface and italics and underlining for reading comprehension, example here. Use section headings and paragraphs liberally. Artificial Intelligence: A Modern Approach has one- to three-word side-notes describing the content of each paragraph. This is very good. Distinguish definitions, proofs, examples, case-studies, code, formulas &c. Dependencies Define terms before they are used. (This is not a joke. Population Genetics uses the term "substitution" on p. 32 without defining it, and exercise 12-1 from Naive Set Theory depends on the axiom of regularity, but the book doesn't define it.) If the book has pre-requisites beyond what a high-schooler knows, a good textbook lists those pre-requisites and textbooks that teach them. Indicators Multiple editions are an indicator for quality. Ditto for multiple authors. A conversational and whimsy style can be nice, but shouldn't be overdone. Hot take: I get very little value from proofs in math textbooks, and consider them usually unnecessary (unless they teach a new proof method). I like the Infinite Napkin for its approach. Wishlist Flashcard sets that come together with textbooks. Please. 3blue1brown style videos that accompany the book. From Zero to Geo is a great step in that direction. Thanks for listening. To help us out with The Nonlinear Library or to learn more, please visit nonlinear.org.
Episode SummaryThe expression of genes in our genome to produce proteins and non-coding RNAs, the building blocks of life, is critical to enable life and human biology. So, the ability to predict how much of a gene is expressed based on that gene's regulatory DNA, or promoter sequence, would help us both understand gene expression, regulation, and evolution, and would also help us design new, synthetic genes for better cell therapies, gene therapies, and other genomic medicines in bioengineering.However, the process by which gene transcription is regulated is incredibly complex; thus, prediction transcriptional regulation has been an open problem in the field for over half a century. In his work, Eeshit used neural networks to predict the levels of gene expression based on promoter sequences. Then, he reverse engineered the model to design specific sequences that can elicit desired expression levels. Eeshit's work developing a sequence-to-expression oracle also provided a framework to model and test theories of gene evolution.About the GuestEeshit earned his double major in CS & Engineering and Biological Sciences & Engineering from the Indian Institute of Technology in Kanpur. During his PhD at MIT, working on Dr. Aviv Regev's team, he published 4 papers in Nature-family journals, including 2 on the cover and 1 on the cover as first and corresponding author. Eeshit's work is in Cell, Nature Biotechnology, Nature Medicine, Nature Communications, and beyond.Key Takeawayscis-regulatory elements like promoters interact with transcription factors in the cell to regulate gene expression.Variation in cis-regulatory elements drives phenotypic variation and influences organismal fitness.Modeling the relationship between promoter sequences and their function – in this case, the expression levels they induce – is important to better understand regulatory evolution and also enable the engineering of regulatory sequences with specific functions with applications across therapeutics and cell-based biomanufacturing.By cloning 50 million sequences into a yellow fluorescent protein (YFP) expression vector in S. cerevisiae and measuring the YFP levels they induced, Eeshit generated a rich dataset to map yeast promoter sequence to expression levels.Next, Eeshit trained neural network models, including convolutional neural networks and Transformers, to predict expression from sequence with high accuracy.Eeshit then “reverse-engineered” these convolutional models to create genetic algorithms that designed sequences which could induce desired expression levels.Finally, Eeshit's sequence-to-expression oracle allowed for the computational evaluation of regulatory evolution across different evolutionary scenarios, including genetic drift, stabilizing selection, and directional selection.ImpactEeshit's work developing a sequence-to-expression oracle provided a framework to model and test theories of gene evolution.This framework can help us both understand gene expression, regulation, and evolution, and design new, synthetic genes for better cell therapies, gene therapies, and other genomic medicines in bioengineering.Paper: The evolution, evolvability and engineering of gene regulatory DNA
Carlos Bustamante, over the past 15 years, has led a multidisciplinary team working on problems at the interface of computational and biological sciences. Much of his research has focused on genomics technology and its application in medicine, agriculture, and evolutionary biology. His first academic appointment was at Cornell University's College of Agriculture and Life Sciences. There, much of his work focused on population genetics and agricultural genomics motivated by a desire to improve the foods we eat and the lives of the animals upon which we depend. He moved to Stanford in 2010, to focus on enabling clinical and medical genomics on a global scale. He has been particularly focused on reducing health disparities in genomics by: (1) calling attention to the problem raised by >95% of participants in large-scale studies being of European descent; and (2) broadening representation of understudied groups, particularly U.S. minority populations and those from Latin America. Taken together, this work has empowered decision-makers to utilize genomics and data science in the service of improving human health and wellbeing. As Inaugural Chair of Stanford's new Department of Biomedical Data Science, his future goal is to scale these operations from focusing on researchers to consumers and patients, where we ultimately want our work to have the greatest impact.In 2017, Bustamante was appointed a Chan-Zuckerberg Investigator and, from 2011–2016, he was a MacArthur Fellow. He also received a Stanford Prize in Population Genetics and Society in 2016, a Sloan Research-Fellowship in Molecular Biology from 2007–2009, and a Marshall-Sherfield Fellowship from 2001–2002. Bustamante also has a strong interest in building new academic units, non-profits, and companies. He is Founding Director (with Marcus Feldman) of the Stanford Center for Computational, Evolutionary, and Human Genomics (CEHG), and former Founding Associate Director of the Cornell Center for Comparative and Population Genomics (3CPG).He serves as an advisor to the US federal government, private companies, startups, and non-profits in the areas of computational genomics, population and medical genetics, and veterinary and plant genomics. He is currently Director of EdenRoc Sciences, Founder @ Arc Bio, & an SAB member of: Embark Veterinary, the Mars/IBM Food Safety Board, & Digitalis Ventures.Alix Ventures, by way of BIOS Community, is providing this content for general information purposes only. Reference to any specific product or entity does not constitute an endorsement nor recommendation by Alix Ventures, BIOS Community, or its affiliates. The views & opinions expressed by guests are their own & their appearance on the program does not imply an endorsement of them nor any entity they represent. Views & opinions expressed by Alix Ventures employees are those of the employees & do not necessarily reflect the view of Alix Ventures, BIOS Community, affiliates, nor its content sponsors.Thank you for listening!BIOS (@BIOS_Community) unites a community of Life Science innovators dedicated to driving patient impact. Alix Ventures (@AlixVentures) is a San Francisco based venture capital firm supporting early stage Life Science startups engineering biology to create radical advances in human health.Music: Danger Storm by Kevin MacLeod (link & license)
Nick talks to genetics researcher & writer Razib Khan. Razib did graduate work in genetics at the University of California-Davis and recently founded a genomics data startup. He also runs a Substack, "Unsupervised Learning," where he writes a lot of fascinating articles on the subjects of human evolutionary & population genetics, personal genomics, and more. Nick and Razib discussed: how the story of human evolution has changed over the past two decades; genomics technology & ancient DNA; Neanderthals, Denisovans & ancient humans; personal genomics (e.g. 23AndMe, Ancestry.com); Razib's experience as a writer on Substack.SUPPORT M&M:Sign up for the free weekly Mind & Matter newsletter:[https://mindandmatter.substack.com/?sort=top]Learn how you can further support the podcast: [https://mindandmatter.substack.com/p/how-to-support-mind-and-matter]Learn more about our podcast sponsor, Dosist[https://dosist.com]ABOUT Nick Jikomes:Nick is a neuroscientist and podcast host. He is currently Director of Science & Innovation at Leafly, a technology startup in the legal cannabis industry. He received a Ph.D. in Neuroscience from Harvard University and a B.S. in Genetics from the University of Wisconsin-Madison.Support the show
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.08.26.504147v1?rss=1 Authors: Knoll, A., Tabbaa, M., Levitt, P. Abstract: Preclinical models of neurodevelopmental disorders typically use single inbred strains which fail to capture human genetic and symptom heterogeneity that is common clinically. We tested if systematically modeling human genetic diversity in mouse genetic reference panels would recapitulate population and individual differences in responses to a syndromic mutation in the high-confidence autism risk gene, CHD8. Trait disruptions mimicked those seen in human populations, including high penetrance of macrocephaly and disrupted behavior, but with robust strain and sex differences. For every trait, some strains exhibited a range of large effect size disruptions, sometimes in opposite directions, and remarkably others expressed resilience. Thus, systematically introducing genetic diversity into mouse models of neurodevelopmental disorders provides a better framework for discovering individual differences in symptom etiologies and improved treatments. Copy rights belong to original authors. Visit the link for more info Podcast created by PaperPlayer
Welcome to episode 22 of the TTM show!This episode is a conversation with my friend Brian Clark. We talked about a wide range of topics including:-Common mistakes made when training the younger population and what age is safe to start training-The importance of understanding the nervous system and the roll it plays in strength/muscle development and recovery- How genetics play a larger roll in strength, endurance, body composition etc. than many people think-Training splits and how to find the right one for you-Why cardio is not the best strategy for weight loss or body composition changes.-How to start training after a long layoff-How to train appropriately for your age and lifting experience-The relationship between training and nutrition-Much moreWhichever platform you're tuning in on, feel free to leave a review! Your feedback is greatly appreciated. The more reviews we receive, the more people the podcast will reach!Also, if you know anyone who loves fitness and podcasts, spread the word! My goal is to help as many people as I can and cut out the BS when it comes to fitness, nutrition and health.Look for weekly (or more) Q&A on my stories. I'll answer your questions on IG and here on the podcast.Programs, blog, nutrition guide (currently free w/any program purchase)terminatortraining.comKickstart- beginner/garage gym friendlyHypertrophy- intermediate/advancedJacked Gazelle- Hybrid athleteFollow Brian: IG: grizwald87Follow me:IG: terminator_trainingTwitter: @ksterminatortmyoutube: Terminator Training Method
Episode 480. Topic: Effective population size. Theme: Population genetics.What is the difference between total population size and effective population size? What is an example of this difference? What causes the difference? What is the effective population size of humans? Will it ever increase?Twitter: @3minutelesson Email: 3minutelesson@gmail.com Instagram: 3minutelesson Facebook: 3minutelesson New episode every Monday, Wednesday, and Friday! Find us everywhere podcasts are found.
Dan Klink examines what the most recent science on population genetics has to do with the Table of Nations in Genesis 10. Message originally given on July 24, 2022.
Episode 479. Topic: Speciation. Theme: Population genetics.Why is it difficult to assign species labels to salamanders? What does this mean for the definition of "speciation"? How do we define human species? What thresholds generally prevent species convergence?Twitter: @3minutelesson Email: 3minutelesson@gmail.com Instagram: 3minutelesson Facebook: 3minutelesson New episode every Monday, Wednesday, and Friday! Find us everywhere podcasts are found.
Episode 478. Topic: Evidence of selection. Theme: Population genetics. What is natural selection? How can you tell from the DNA of a species when and where natural selection has occurred? What in recent human evolution has undergone natural selection?Twitter: @3minutelesson Email: 3minutelesson@gmail.com Instagram: 3minutelesson Facebook: 3minutelesson New episode every Monday, Wednesday, and Friday! Find us everywhere podcasts are found.
Today's ID the Future continues intelligent design theorist Casey Luskin's conversation with Apologetics 315 podcast hosts Brian Auten and Chad Gross. Here in Part 2, Luskin give a peek behind the scenes of ID 3.0, the current research program inspired by the intelligent design framework. Luskin is then asked to explain his reservations about theistic evolution, and Luskin points out the evidential, rhetorical, and logical problems he sees with the brand of theistic evolution advocated by Francis Collins and Biologos. What about the future of the intelligent design movement? Luskin says he's optimistic, both because of the exciting research and publication breakthroughs of late, and because of the many converts he's seeing to the ID framework. According to Luskin, many of these Read More › Source
Episode 477. Topic: The founder effect. Theme: Population genetics.How can reduced genetic diversity alter the frequency of traits? Can this be dangerous? What are some founder effect examples in humans? What caused them? Twitter: @3minutelesson Email: 3minutelesson@gmail.com Instagram: 3minutelesson Facebook: 3minutelesson New episode every Monday, Wednesday, and Friday! Find us everywhere podcasts are found.
Episode 476. Topic: Genetic drift. Theme: Population genetics.How can traits change frequency in a population without natural selection? What is genetic drift? What would this look like in a population?Twitter: @3minutelesson Email: 3minutelesson@gmail.com Instagram: 3minutelesson Facebook: 3minutelesson
Have a dog with cancer and wish there was something you could do – right now – to help other dogs avoid this disease? Enter Darwin's Ark. The Darwin's Ark Cancer Project is a free, survey-based project that is looking for trends that could pinpoint why some dogs get cancer and why others don't. Some of the participants will also get a free genome sequencing and/or a silicone tag to help pick up pollutants that your dog is exposed to. Blood samples may also be collected from some dogs to evaluate tumor DNA circulating in the bloodstream. Listen in to learn more about Darwin's Ark, how to sign up, and how your dog's data will be used. Links Mentioned in Today's Show: Darwin's Ark Darwin's Ark Cancer Project Dog Aging Project About Today's Guest, Dr. Michelle White: My career focus is Precision Medicine and Veterinary Genetics and Genomics. I received my DVM (Doctor of Veterinary Medicine) degree from Cornell University in May of 2014, and my PhD in Translational Medicine with a minor in Genetics and Genomics in 2019 (also from Cornell). Specialties: Veterinary Medicine, Data Analysis, Translational Research, Population Genetics, Project Management, Financial Planning LinkedIn Twitter Other Links: To join the private Facebook group for readers of Dr. Dressler's book “The Dog Cancer Survival Guide,” go to https://www.facebook.com/groups/dogcancersupport/ Dog Cancer Answers is a Maui Media production in association with Dog Podcast Network This episode is sponsored by the best-selling animal health book The Dog Cancer Survival Guide: Full Spectrum Treatments to Optimize Your Dog's Life Quality and Longevity by Dr. Demian Dressler and Dr. Susan Ettinger. Available everywhere fine books are sold. Have a guest you think would be great for our show? Contact our producers at DogCancerAnswers.com Have an inspiring True Tail about your own dog's cancer journey you think would help other dog lovers? Share your true tail with our producers. If you would like to ask a dog cancer related question for one of our expert veterinarians to answer on a future Q&A episode, call our Listener Line at 808-868-3200 www.dogcanceransers.com. Dog Cancer News is a free weekly newsletter that contains useful information designed to help your dog with cancer. To sign up, please visit: www.dogcancernews.com Learn more about your ad choices. Visit megaphone.fm/adchoices
On today's ID the Future, physicist and engineer Brian Miller sits down with host Casey Luskin to survey exciting developments in intelligent design research that are driven by an engineering model for understanding and studying variations in species. ID researchers are pushing this work, but so too are systems biology researchers outside the intelligent design community. Tune in to hear Miller and Luskin discuss everything from fruit flies, finch beaks, and stickleback fish to mutational hotspots, phenotypic plasticity, and the gravity well model of biological adaptation. Source
In this episode, we review the high-yield topic of Population Genetics from the Biochemistry section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://anchor.fm/medbulletsstep1/message
My AP Biology Thoughts Unit 7 Natural Selection EPISODE TITLE: Unit 7: Darwin's FinchesWelcome to My AP Biology Thoughts podcast, my name is Shrithik Sekar, Kyle Mason, Gabe Moriello, and I am your host for Unit 7: Examples of Evolution, Darwin's Finches. In episode 116, we will be discussing this topic and how it relates to the AP Biology Curriculum. “We want to also thank our sources for the information presented in this podcast episode today which include (Britannica, Galapogosisland.org, and Crash course Biology on Youtube). You can find the citations and links to these sources in the show notes.” Segment 1: Overview of Darwin's finches What are Darwin's finches? Who is darwin? - Geologist and Biologist, who formed the theory of natural selection. Known for his contributions to Science of evolution. He studied many finches which were found in the galapagos islands located 1,000 km off the coast of Ecuador What were the finches? - These finches were a Group of 18 different species found in the Galapagos island. Darwin found the finches were all closely related with small direct observations that he made during his time in the Galapagos islands What did he study? -During his studies while in the Galapagos islands, he concluded the speciation of the finches which is known as the experiment of Darwin's finches How does it relate to evolution? - It relates to evolution because it is an example of Direct observation Segment 2: Evidence that supports Darwin's finches Connection direct observation evolution What is direct observation of evolution? - Through observation, in small population sizes, it can be found many changes of one species to then create many subspecies. Through direct observation of evidence in almost every species. THis idea had to do with the last universal ancestor, how all species are alike in many ways and all stemmed from the same ancestor. These finches dna is super similar, but these small differences of dna created a difference in appearance which was found ny darwin. ( This begs the question of ) Why are the finches an example of evolution? All 18 species of Darwin's Finches were originally one finch species on the coast of south america. However, Darwin discovered that this species branched off into 18 different species on the Galapagos islands depending on the finches' environment What Key pieces of evidence did darwin find? - Darwin found the difference, fruit eating finches had wide beaks, insect eating finches had narrow beaks, and based on different factors of each finches environment each species had a different characteristic change. - GO TO Image Segment 3: Connection to the CourseThe 5 pieces of evidence - of evolution. How do these ideas of evolution connect to our Biology class? ( Relates to AP bio curriculum 7.2 - Natural Selection) ( 7.4 - Population Genetics (7.6 - Evidence of evolution (7.7 - Common Ancestry Direct observation is only one example of evolutionary evidence 5 other examples - Fossils, Geological evidence, Change in DNA, Homologous structures All apart of either natural or physiological selection Natural selection is a part of the 5 fingers of evolution ( Sexual Selection, Genetic Drift, Gene flow, Mutation) Darwin's finches show that adaptive evolution among the finch populations - the finches evolved different beak types depending on which food they ate, showing how natural selection is a factor in pushing populations to evolve Thank you for listening to this episode of My AP Biology Thoughts. For more student-ran podcasts and digital content, make sure that you visit http://www.hvspn.com (www.hvspn.com). Ceeeyaaa!!!!!! Music Credits: "Ice Flow" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License...
Razib Khan is a Bangladeshi-American writer in Population Genetics & Consumer Genomics. He is a Public Intellectual & works at Insitome & has written publications for The New York Times, City Journal, India Today, National Review, Quillette, The Guardian & MIT Technology Review, etc. Razib Khan: https://razib.com ; https://razib.substack.com/ Sanjana Singh (The Host): https://linktr.ee/sanjanasingh ; sanjanasingh.substack.com The Naked Dialogue Podcast: https://linktr.ee/TheNakedDialogue --- Support this podcast: https://anchor.fm/sanjanasinghx/support
In this episode, Ruby and Laura spoke to Bianca De Sanctis, a PhD student in Professor Eske Willerslev's research group in the Department of Zoology at the University of Cambridge. Bianca's research focuses on genome reconstruction using ancient DNA samples to gain a snapshot of what ancient ecosystems looked like. Bianca fills us in on a recently published study where she and her colleagues reconstructed the genomes of a Stone Age American black bear and an extinct short-faced bear using environmental DNA samples from a remote cave in Mexico. She also discusses the difficulty of working with ancient DNA samples, and how the use of ancient environmental DNA samples has provided a huge leap forward in the world of ancient genomics. You can find out more about Bianca's latest paper here: https://www.cam.ac.uk/research/news/stone-age-bear-genome-reconstructed-from-dna-in-mexican-cave The BlueSci Podcast is run by the Cambridge University Science Magazine. This episode was hosted by Ruby Coates, Simone Eizagirre and Laura Chilver and sponsored by Greiner Bio-One and Nature Careers. Visit www.bluesci.co.uk to access our free magazine, and find out how to get involved. If you enjoyed this episode, please subscribe and leave a review or rating! We welcome your feedback and suggestions via email: podcast(at)bluesci.co.uk. You can also follow us on Twitter on @bluescipod.
Today's ID the Future spotlights the incredible fine tuning of life. Robert J. Marks hosts Stockholm University professor of mathematical statistics Ola Hössjer and University of Miami population geneticist Daniel Díaz. The three discuss strategies for extending the concept of fine tuning to biological systems, and along the way touch on population genetics, entropy, and probability theory. At the center of the discussion are three technical papers—here, here, and here—each co-authored by one or more of the three members of today's podcast discussion. This episode is reposted with permission from Mind Matters News, a website of Discovery Institute's Walter Bradley Center for Natural and Artificial Intelligence. Head over to their podcast site to find the other episodes in this interview Read More › Source
There are many examples in biology of the incredible fine-tuning of life. On this episode of Mind Matters, you’ll learn about fine-tuning, population genetics, and probability as Robert J. Marks speaks with Ola Hössjer and Daniel Díaz. Show Notes 00:47 | Introducing Dr. Daniel Díaz 01:00 | Introducing Dr. Ola Hössjer 01:14 | Fine-tuning in biology 07:15 | A cellular… Source
This week we're talking about population genetics, what it is, why it's important, how this relates to endangered species, how it is used, and some interesting new legislature that addresses a major concern with this issue!For full show notes visit our website: sciencemanagementsymbiosis.com
#crispr #genetics #stanforduniversity #invitrogametogenesis #dna #geneticeditingHenry T. (Hank) Greely specializes in the ethical, legal, and social implications of new biomedical technologies, particularly those related to genetics, assisted reproduction, neuroscience, or stem cell research. He is a founder and immediate past president of the International Neuroethics Society; a member of the Multi-Council Working Group of the NIH's BRAIN Initiative, whose Neuroethics Working Group he co-chairs; chair of the Ethical, Legal, and Social Issues Committee of the Earth BioGenome Project; and chair of California's Human Stem Cell Research Advisory Committee. He served as a member of the Committee on Science, Technology, and Law of the National Academies from 2013-2019; Neuroscience Forum of the Institute of Medicine from 2012-2019; as a member of the Advisory Council of the NIH's National Institute for General Medical Sciences from 2013-2016; and from 2007-2010 as co-director of the Law and Neuroscience Project. Professor Greely chairs the steering committee for the Stanford Center for Biomedical Ethics and directs both the law school's Center for Law and the Biosciences and the Stanford Program in Neuroscience and Society. Greely is also a professor (by courtesy) of genetics at Stanford School of Medicine. In 2007 Professor Greely was elected a fellow of the American Association for the Advancement of Science, received Stanford University's Richard W. Lyman Award in 2013, and the Stanford Prize in Population Genetics and Society in 2017. He published The End of Sex and the Future of Human Reproduction in 2016 plus CRISPR People: The Science and Ethics of Editing Humans. Before joining the Stanford Law School faculty in 1985, Greely was a partner at Tuttle & Taylor, served as a staff assistant to the secretary of the U.S. Department of Energy, and as special assistant to the general counsel of the U.S. Department of Defense. He served as a law clerk to Justice Potter Stewart of the U.S. Supreme Court and to Judge John Minor Wisdom of the Court of Appeals for the Fifth Circuit. https://law.stanford.edu/directory/henry-t-greely/ https://twitter.com/hankgreelylsju Watch our highest viewed videos: 1-India;s 1st Quantum Computer- https://youtu.be/ldKFbHb8nvQ DR R VIJAYARAGHAVAN - PROF & PRINCIPAL INVESTIGATOR AT TIFR 2-Breakthrough in Age Reversal- -https://youtu.be/214jry8z3d4 DR HAROLD KATCHER - CTO NUGENICS RESEARCH 3-Head of Artificial Intelligence-JIO - https://youtu.be/q2yR14rkmZQ Shailesh Kumar 4-STARTUP FROM INDIA AIMING FOR LEVEL 5 AUTONOMY - SANJEEV SHARMA CEO SWAAYATT ROBOTS -https://youtu.be/Wg7SqmIsSew 5-TRANSHUMANISM & THE FUTURE OF MANKIND - NATASHA VITA-MORE: HUMANITY PLUS -https://youtu.be/OUIJawwR4PY 6-MAN BEHIND GOOGLE QUANTUM SUPREMACY - JOHN MARTINIS -https://youtu.be/Y6ZaeNlVRsE 7-1000 KM RANGE ELECTRIC VEHICLES WITH ALUMINUM AIR FUEL BATTERIES - AKSHAY SINGHAL -https://youtu.be/cUp68Zt6yTI 8-Garima Bharadwaj Chief Strategist IoT & AI at Enlite Research -https://youtu.be/efu3zIhRxEY 9-BANKING 4.0 - BRETT KING FUTURIST, BESTSELLING AUTHOR & FOUNDER MOVEN -https://youtu.be/2bxHAai0UG0 10-E-VTOL & HYPERLOOP- FUTURE OF INDIA"S MOBILITY- SATYANARAYANA CHAKRAVARTHY -https://youtu.be/ZiK0EAelFYY 11-NON-INVASIVE BRAIN COMPUTER INTERFACE - KRISHNAN THYAGARAJAN -https://youtu.be/fFsGkyW3xc4 12-SATELLITES THE NEW MULTI-BILLION DOLLAR SPACE RACE - MAHESH MURTHY -https://youtu.be/UarOYOLUMGk Connect & Follow us at: https://in.linkedin.com/in/eddieavil https://twitter.com/intothechange
This week Brett chats with Sam Schaick, a Large River Fisheries Ecologist at the Illinois Natural History Survey's Illinois River Biological Station about his early life in Wisconsin, his undergrad experience at Stevens Point, his graduate research at Eastern Illinois University, and some fisheries projects he is currently working on. Remember, it is okay to say "I don't know!" Check out more of his work! M.S. Research at EIU: https://thekeep.eiu.edu/cgi/viewcontent.cgi?article=5849&context=theses Twitter: @samuelJschaick Email: sschaick@illinois.edu ------------------------------------------------------------------------------------------------- Fisheries Podcast Merch! https://teespring.com/stores/the-fisheries-podcast-fan-shop Don't forget to find us on Facebook and other social media platforms https://www.facebook.com/FisheriesPod/ @Fisheries Pod Thanks Andrew Gialanella for the intro/outro music. Photo Credit: Sam Schaick
Can the molecular biology of flies serve as an indicator for the health of the environment around them? Insects around the world can give insights into how the area around them operates. Press play to learn: How an oil spill in the Gulf of Mexico affected Louisiana's ecosystem If the microbiome inside a fly can hint at the health of the animals that they feed on Why horseflies were chosen to gauge the health of the ecosystem Claudia Husseneder, professor of urban entomology at LSU, drops by to share her experience working around the world studying population genetics and how it impacts the area around them. Using the principles of epigenetics, traits passed down in horsefly populations can give hints about their surroundings. The population decrease of flies in affected areas of the oil spill leads to the conclusion that part of the ecosystem has been negatively impacted, causing it not to sustain as large of a population. If genetic diversity in a population is reduced, new and rare genetic variants are taken out of the future's hereditary pool. Population genetics applications can explain not only this but why it can spell disaster for the area around them. For more information, visit https://www.lsu.edu/entomology/. Episode also available on Apple Podcasts: apple.co/30PvU9C
If one little baby ape, a long long time ago, had an especially helpful mutation, how long would it take before all apes inherited that single genetic improvement? Biologist Christopher Rupe (colleague of last week's guest, geneticist John Sanford) helps Real Science Radio get a better understanding of the science of population genetics. Bob Enyart asks Rupe about something called genetic fixation, about alleles, and the percentage of mutations that are beneficial. The discussion also asks, with the distribution of helpful mutations being exceedingly slower than a snail's pace, what is the pace of the accumulation of harmful mutations? Listeners will also learn about the test of the ape-to-man hypothesis, about how dissimilar chimp DNA is from the human genome, and why the Y chromosome should be the most similar but it is so wildly different that it's as close to a chick Y as a chimp Y! See also Mendel's Accountant, the web's software tool to simulate the theory of evolution. (Finally, we're working on getting a video of Rupe's college lecture so we can embed it on this page. And in the meantime, here's Chris' colleague's lecture at NIH:
If one little baby ape, a long long time ago, had an especially helpful mutation, how long would it take before all apes inherited that single genetic improvement? Biologist Christopher Rupe (colleague of last week's guest, geneticist John Sanford) helps Real Science Radio get a better understanding of the science of population genetics. Bob Enyart asks Rupe about something called genetic fixation, about alleles, and the percentage of mutations that are beneficial. The discussion also asks, with the distribution of helpful mutations being exceedingly slower than a snail's pace, what is the pace of the accumulation of harmful mutations? Listeners will also learn about the test of the ape-to-man hypothesis, about how dissimilar chimp DNA is from the human genome, and why the Y chromosome should be the most similar but it is so wildly different that it's as close to a chick Y as a chimp Y! See also Mendel's Accountant, the web's software tool to simulate the theory of evolution. (Finally, we're working on getting a video of Rupe's college lecture so we can embed it on this page. And in the meantime, here's Chris' colleague's lecture at NIH:
Dr. Bill Andrews rejoins the program to discuss the real possibilities of reverse aging technologies and telomere lengthening. We discuss the desire for almost everyone wanting to improve the quality of life as they age. He also discusses how almost all diseases we have not solved yet are in fact, diseases of aging. You can learn more about Dr. Bill Andrews work and business opportunities with his company at www.sierrasci.com See the show on SarahWestall.TV and get access on Roku, Apple TV, Google TV and more – Sign up at SarahWestall.TV C60Complete Black Seed Oil & Curcumin Gel Capsules - Proven 200x more effective than Vitamin C! Consider supporting this channel by joining SubscribeStar at SubscribeStar.com/Sarah-Westall – See exclusive interviews and more. Note: Patreon suspended my channel due to questioning the election legitimacy, covering child trafficking and challenging the narrative. Sign up for my newsletter and other platforms @ SarahWestall.com/Subscribe MUSIC CREDITS: “The Battle of 1066” by Patrick Patrikios – licensed for broad internet media use, including video and audio See the video on Bitchute | Rumble | Odysee | SarahWestall.tv See more information on great products, including the C60 BlackSeed Oil Gel Caps, Telomere Lengthening, and much more @ http://SarahWestall.com/Shop Dr. Bill Andrews Biography Dr. Bill Andrews is the president and CEO of Sierra Sciences. He has worked in the biotech industry for 28 years, focusing the last 15 years on finding ways to extend human lifespan through the intervention of telomere shortening in human cells. Dr. Andrews earned his Ph.D. in Molecular and Population Genetics at the University of Georgia in 1981. He was a Senior Scientist at Armos Corporation and Codon Corporation, Director of Molecular Biology at Codon and at Geron Corporation, and Director of Technology Development at EOS Biosciences. While Director of Molecular Biology at Geron Corporation from 1992 to 1997, Dr. Andrews was one of the principal discoverers of both the RNA and protein components of human telomerase and was awarded 2nd place as "National Inventor of the Year" in 1997 for this work. He is presently a named inventor on 35 US issued telomerase patents. Dr. Andrews is an avid runner and enjoys participating in ultramarathons in his spare time. His ultimate goal is to run a 7 minute mile at the age of 130. Learn more about Dr. Bill Andrews at www.sierrasci.com
Today’s ID the Future extends the discussion of A Mousetrap for Darwin: Michael Behe Answers His Critics, the newest book from Discovery Institute Press. Here the focus is on Parts 4 and 7 of the new book, and in particular Richard Lenski’s Long Term Evolution Experiment at Michigan State. What has this long-running project demonstrated? As Behe explains in the book (and elaborates on in today’s podcast), “The study has addressed some narrow points of peculiar interest to evolutionary population geneticists, but for proponents of intelligent design the bottom line is that the great majority of even beneficial mutations have turned out to be due to the breaking, degrading, or minor tweaking of pre-existing genes or regulatory regions. There have Read More › Source
Welcome to My AP Biology Thoughts podcast, my name is Shriya and I am your host for episode 5 called “Population Genetics: Central Dogma, Allele Frequency Equation and Gene Pools.” Today we will be discussing the definitions of all of those concepts as well as a few examples to go along with them. Then, we will connect all of that to the overarching topic of evolution. Hope you enjoy! Segment 1: Introduction to Population Genetics: Central Dogma, Allele Frequency Equation and the Gene PoolIntroduce the episode topic Include definitions and vocabulary Will be discussing the topic of population genetics which is the study of genetic variation within a population and looking into changes in the frequencies of genes and alleles in populations over time Natural selection is one of the most influential factors that can affect a population's genetic composition Central dogma of biology is when the instructions contained in DNA are converted into a functional product, a phenotype DNA, contains the genes that determine who you are, and proteins determine the structure and function of all your cells It describes the two-step process, transcription and translation, of how information in genes flow into proteins, creating a string of amino acids called polypeptides The DNA has the information which is used by the RNA to make the proteins The Allele Frequency Equation: an allele is a version of a gene and a heritable unit that controls a particular feature of an organism The allele frequency refers to how often a particular allele appears in a population An equation called the Hardy-Weinberg equation is used to calculate the genetic variation in a population: p^2 + 2pq + q^2 p^2 and q^2 are the allele frequencies of the homozygous recessive and homozygous dominant, and 2pq is the allele frequency of the heterozygous genotypes To get p and q individually, you calculate actual/total # of alleles With this knowledge, you are able to calculate the total allele frequencies using the equation p + q = 1 The gene pool is calculated using the equation just mentioned, p + q = 1 since it is the sum of both allele frequencies A gene pool is the collection of different genes within an interbreeding population, and refers to its genetic diversity The larger the gene pool, the greater genetic diversity, and the better a population is able to withstand environmental challenges Segment 2: Examples of Population GeneticsHave a natural transition into an example… no need to say “segment 2” Provide detailed example(s) of your topic This first example is a depiction of the central dogma and the different processes at work from Khan Academy DNA directs the construction of the chain of amino acids through transcription, which is when the DNA sequence of a gene is copied to make an RNA molecule During the second process, translation, mRNA is decoded to specify the amino acids of the polypeptide chain Overall, information flows from DNA to RNA to a protein, and this directional flow is why it is the central dogma of molecular biology An example using pea plants demonstrates how to calculate the allele frequency of a population using the total number of alleles and fractions There are 9 pea plants, meaning 18 total alleles 6 of them are homozygous dominant (WW), 1 is heterozygous (Ww), and 2 are homozygous recessive (ww) To calculate p and q, set up fractions and convert them into percentages There are 13 copies of the W allele and 5 copies of the w allele, so the allele frequencies for each are 72% and 28% respectively If you notice, they add up to 1, or 100% To show a gene pool, here is a picture of butterflies of 3 different colors: orange, white, brown You can see the diversity in the population through the different allele combinations: AA (brown), Aa(orange), aa (white) Segment 3: Digging Deeper into Population GeneticsHow does this topic fit into the greater picture of evolution? The...
Model the formation of new combinations of genotypes produced during meiosis, including but not limited to: – constructing and interpreting information and data from pedigrees and Punnett squares Collect, record and present data to represent frequencies of characteristics in a population, in order to identify trends, patterns, relationships and limitations in data, for example: – examining frequency data – analysing single nucleotide polymorphism (SNP) Thanks to STEM Reactor for sponsoring this podcast. They provide everything you need to do biotechnology at school, check them out at www.stemreactor.com.au
This MCAT podcast covers population genetics. I discuss genotypes and phenotypes, inheritance patterns, and the Hardy-Weinberg equation. In addition, I talk about the four ways that a population’s genetics can change over time i.e. natural selection, mutation, genetic drift and gene flow. [01:09] The Difference Between Population Genetics and Molecular Genetics [01:54] Defining Genotypes and Phenotypes [06:24] The Six Inheritance Patterns [13:27] The Hardy-Weinberg Equation [26:17] Natural Selection [32:22] Mutation [36:47] Genetic Drift [40:04] Gene Flow For any comments and/or concerns please email me: MCATpodcast@medschoolcoach.com Thanks for listening! http://merch.medschoolcoach.com/ Code: PODCAST5 Facebook live stream: https://go.medschoolcoach.com/podcast
Dr. Hou-Feng Zheng is Principal Investigator at Westlake University researching bioinformatic tools for the analysis of large genetic data and complex disease. Westlake Profile ► https://bit.ly/Hou-Feng Google Scholar ► https://bit.ly/Hou-FengGS LinkedIn ► https://bit.ly/Hou-FengLinkedIn Research Gate ► https://bit.ly/Hou-FengRG Recent Paper ► https://bit.ly/Hou-FengPaper CHINA
Episode 41 recAPs the random side of evolution. Melanie begins with a vocab review - allele, gene, heterozygous (1:00). This episode is about population genetics because populations are the level of ecological organization where evolution occurs (1:40). Mutations are the primary source of genetic variation, providing new phenotypes on which natural selection can act (2:40). It's important to distinguish between gene flow and genetic drift (3:24). Two types of genetic drift are the bottleneck effect (4:10) and the founder effect (4:50).The Question of the Day asks (6:30) “What do the p and q represent in Hardy-Weinberg equilibrium?Thank you for listening to The APsolute RecAP: Biology Edition!(AP is a registered trademark of the College Board and is not affiliated with The APsolute RecAP. Copyright 2020 - The APsolute RecAP, LLC. All rights reserved.)Website:www.theapsoluterecap.comEMAIL:TheAPsoluteRecAP@gmail.comFollow Us:INSTAGRAMTWITTER
David and Grace talk about abstraction in statistics, computing, mathematics and a few other things besides. Birth-death process (https://en.wikipedia.org/wiki/Birth–death_process) Akaike information criterion (https://en.wikipedia.org/wiki/Akaike_information_criterion) Stratechery by Ben Thompson (https://stratechery.com) Subtraction.com (https://www.subtraction.com) The Law of Leaky Abstractions (https://www.joelonsoftware.com/2002/11/11/the-law-of-leaky-abstractions/) Logic gate (https://en.wikipedia.org/wiki/Logic_gate) The 10,000 Domino Computer (https://youtu.be/OpLU__bhu2w) CS50's Introduction to Computer Science (https://www.edx.org/course/cs50s-introduction-to-computer-science) Floating-point arithmetic (https://en.wikipedia.org/wiki/Floating-point_arithmetic) Single Variable Calculus (https://ocw.mit.edu/courses/mathematics/18-01sc-single-variable-calculus-fall-2010/) Zone of proximal development (https://en.wikipedia.org/wiki/Zone_of_proximal_development) principle of specificity (https://www.oxfordreference.com/view/10.1093/oi/authority.20110810105645210) Progressive overload (https://en.wikipedia.org/wiki/Progressive_overload) Species distribution modelling (https://en.wikipedia.org/wiki/Species_distribution_modelling) Population genetics (https://en.wikipedia.org/wiki/Population_genetics) Coalescent theory (https://en.wikipedia.org/wiki/Coalescent_theory)
Researchers from the University of Western Australia (UWA) and Baylor College of Medicine, in the US state of Texas, are collaborating towards developing a new diagnostic test for COVID-19. Through genome sequencing, this novel test potentially explores mutations across various strains of this coronavirus, aid vaccine development and understand its journey across populations globally.
The Molecular Ecologist Podcast made it to a second episode! Thanks for listening to our first one, and for all the positive comments. In addition to our "home" hosting service, Anchor.fm, you can now subscribe to the podcast on Apple Podcasts, Pocket Casts, and Spotify — or you can add the RSS feed URL directly to your podcast-management app of choice. Whatever service you use, consider taking a moment to rate or even review the podcast, which will help us build an audience. On this episode, Stacy Krueger-Hadfield and Sabrina Heiser talk about Stacy's #StudentScicomm initiative, using science blogging as an assignment in graduate-level professional development and science courses. Kelle Freel describes the results of a community genetics survey of diversity within an algae bloom that travels the North Atlantic every year, by Bolaños et al. (doi: 10.1038/s41396-020-0636-0) R. Shawn Abrams previews an upcoming post about new research supporting the hypothesis that symbiosis with nitrogen-fixing bacteria had a single origin in the common ancestor of the clade that includes legumes, roses, and oaks. Jeremy Yoder recaps a new simulation study that shows how populations distributed continuously across space (which is to say, most natural populations) confound and complicate population genetic analyses, by Battey et al. (doi: 10.1534/genetics.120.303143) The music in this episode is Leroy Anderson's "The Syncopated Clock," performed on piano by Markus Staab and available under a Creative Commons license via Musopen. --- Send in a voice message: https://anchor.fm/molecular-ecologist/message
In this lecture Professor Alison Etheridge explores some of the simple mathematical caricatures that underpin our understanding of modern genetic data. How can we explain the patterns of genetic variation in the world around us? The genetic composition of a population can be changed by natural selection, mutation, mating, and other genetic, ecological and evolutionary mechanisms. How do they interact with one another, and what was their relative importance in shaping the patterns we see today?
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