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mRNA vaccines are not supposed to contain DNA. But Dr. Jessica Rose says a new study tested “32 vials of Pfizer and Moderna COVID products that included 16 unique lots… We did not only find DNA, we found it in ALL lots tested and most importantly, the DNA levels were all above pre-designated EMA thresholds of 10 ng/dose.” “We measured the amount of DNA in the vials using 2 methods… (qPCR and fluorometry),” she continues. “It was submitted as evidence on the congressional record by the honorable Senator Ron Johnson.” JP Sears is a comedian, author, and YouTuber known for his satirical take on politics, fitness, and faith. He hosts Awaken with JP on Rumble and YouTube. Follow at https://x.com/AwakenWithJP Dr. Jessica Rose is a Canadian researcher with a Bachelor's in Applied Mathematics and a Master's in Immunology from Memorial University of Newfoundland. She holds a PhD in Computational Biology from Bar Ilan University and completed postdoctoral research in Molecular Biology and Biochemistry. Find her at https://jessicasuniverse.com and follow at https://x.com/JesslovesMJK 「 SUPPORT OUR SPONSORS 」 Find out more about the brands that make this show possible and get special discounts on Dr. Drew's favorite products at https://drdrew.com/sponsors • FATTY15 – The future of essential fatty acids is here! Strengthen your cells against age-related breakdown with Fatty15. Get 15% off a 90-day Starter Kit Subscription at https://drdrew.com/fatty15 • PALEOVALLEY - "Paleovalley has a wide variety of extraordinary products that are both healthful and delicious,” says Dr. Drew. "I am a huge fan of this brand and know you'll love it too!” Get 15% off your first order at https://drdrew.com/paleovalley • VSHREDMD – Formulated by Dr. Drew: The Science of Cellular Health + World-Class Training Programs, Premium Content, and 1-1 Training with Certified V Shred Coaches! More at https://drdrew.com/vshredmd • THE WELLNESS COMPANY - Counteract harmful spike proteins with TWC's Signature Series Spike Support Formula containing nattokinase and selenium. Learn more about TWC's supplements at https://twc.health/drew 「 MEDICAL NOTE 」 Portions of this program may examine countervailing views on important medical issues. Always consult your physician before making any decisions about your health. 「 ABOUT THE SHOW 」 Ask Dr. Drew is produced by Kaleb Nation (https://kalebnation.com) and Susan Pinsky (https://twitter.com/firstladyoflove). This show is for entertainment and/or informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment. Learn more about your ad choices. Visit megaphone.fm/adchoices
Dalton SizemoreBiology with Heart, Humor, and a DrawlI'm Dalton — a molecular biologist, science communicator, and caregiver. I hold a BS and MS in Cell and Molecular Biology from Appalachian State University, where I focused on cancer biology, virology, and immunology. My research explored how viruses like VSV might be used to disrupt the immune processes that help cancer metastasize. I also hold a graduate certificate in clinical psychology, which helps me bridge the gap between the science of the body and the realities of the human experience.But the truth is, everything I've done in science is rooted in something far more personal.I'm a survivor of childhood abuse. My father left when I was young, and my mother — who raised me on her own — endured two severely abusive relationships: one during my childhood, and another while I was in high school and starting college. Those years shaped me deeply. They taught me what it means to live in chaos and still push forward, to carry pain and still protect others, and to learn, even when nothing in your life feels safe.While I was earning my degrees, I was also a full-time caregiver. My mom nearly died from a MRSA infection that turned into a kidney crisis. My grandmother is disabled and was one of the first people in the U.S. to receive an implantable defibrillator. My sister has a seizure disorder that renders her disabled. At 22, I was managing emergency care, making medical decisions, studying biochemistry and organic chemistry, and trying not to fall apart.Want to be a guest on Book 101 Review? Send Daniel Lucas a message on PodMatch, here: https://www.podmatch.com/hostdetailpreview/17372807971394464fea5bae3 Hosted on Acast. See acast.com/privacy for more information.
ReferencesInt J Mol Sci. 2022 Jul 8;23(14):7592. Exp Mol Med . 2024 Apr;56(4):946-958.Front Endocrinol (Lausanne). 2020 Jul 29;11:483.Nature Structural & Molecular Biology 2025 .32, pages431–440 Kath, T. 1970.Memories of Love Chicago II https://music.youtube.com/watch?v=GFjWeUnt6nY&si=mHjfAhTlwVyXE0ZMSchubert, F. 1829. Standchen 4 D 957https://music.youtube.com/watch?v=pJf-XXTBEqs&si=2fMoDFFsHz_i1H0GSimon, P. 1966. Scarborough Fare.https://music.youtube.com/watch?v=-Jj4s9I-53g&si=OA7lBVGkiPXlPpoJLennon/McCartney. 1966. Rainhttps://music.youtube.com/watch?v=nrEgtOeJGzQ&si=D1lQwT-_ck2pBD_X
Cultural humility is a lifelong practice of self-reflection, openness, and respect for the diverse backgrounds of the families we serve. Unlike cultural competence, which can imply mastering knowledge about “other cultures,” cultural humility emphasizes curiosity, listening, and shared decision-making. In pediatrics, this is especially important because care involves both the child and the family, whose cultural values strongly shape health beliefs and practices.Today's discussion is an opportunity to reflect together: how do we approach cultural humility in pediatrics, and what steps can we take to deepen it in our daily practice?Dr. Ana Aguilar, DO is originally from Loveland, OH. She went to Transylvania University where she did not major in Blood-Sucking and Shadow-Walking, but instead earned a dual degree in Molecular Biology and Anthropology. She attended Ohio University Heritage College of Osteopathic Medicine and is a very recent Loyola graduate, now completing a chief year with her best friend and co-chief, Dr. Sana Moqeet, MD. In her spare time, Ana enjoys reading, solving puzzles, writing and denying vampire allegations.Episode produced by: Deborah ChenEpisode recording date: 09/11/2025www.medicuspodcast.com | medicuspodcast@gmail.com | Donate: http://bit.ly/MedicusDonate
On this episode of ID the Future selected out of our vault, host Eric Metaxas begins a conversation with biologist and professor Dr. Douglas Axe on The Eric Metaxas show. Axe is the Maxwell Professor of Molecular Biology at Biola University, the founding Director of Biologic Institute, the founding Editor of BIO-Complexity, and the author of Undeniable: How Biology Confirms Our Intuition That Life is Designed. In Part 1, Dr. Axe shares how he lost his research position in Cambridge during a season of political controversy over Darwinian evolution in the UK. He also shares what he learned from his experiments in protein evolution that cast doubt on the neo-Darwinian explanation for life. This is Part 1 of a two-part conversation. Source
In this Mol Bio Minutes episode, Dr. Will Barnes, a plant biologist turned senior sales training specialist at Thermo Fisher Scientific, reflects on his time at the bench and the molecular lessons learned along the way. Will dives deep into the difficulties of RNA work in plant systems—carbohydrate contamination, genomic DNA carryover, secondary structure—and how these hindered everything from cloning and expression analysis to sequencing and qPCR.Through real-world anecdotes, he explains how high-quality reagents and systems helped him troubleshoot and resolve recurring issues, ultimately saving time and improving data reliability. He advocates for prioritizing upstream steps like RNA integrity and reverse transcription fidelity instead of chasing fixes at the end of the workflow.Listeners will leave with a deeper appreciation for the critical role of sample prep in molecular biology workflows and why investing in better tools pays off in cleaner data, greater confidence, and fewer headaches. Will's experience is a relatable reminder that smarter choices lead to better science.Helpful resource links mentioned in this episode:Learn about molecular cloning workflows and Gateway cloning solutionsExplore a variety of resources on reverse transcriptionTaqMan vs SYBR Chemistry for Real-Time PCRUsing MagMAX kits for automated nucleic acid extractionLearn more about, or order,SuperScript IV VILO Master MixExplore RNA/DNA quantification solutions, including Qubit and Nanodrop instruments----------------------------------------------------------------------------------------------Limited time promotional offer – Be one of the first 75 listeners to spend $500 and get 40% off all eligible reverse transcriptase, plastics, enzymes, and cloning reagents. Visit thermofisher.com/sombpromo for full detailsEnter promo code CAZDUA in the U.S.A.Enter promo code CZ7F19 in Canada Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague. Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.
In this episode, Dr. Bill Andrews joins Dr. Buck Joffrey to discuss the critical role of telomeres and telomerase in aging and cellular health. He explains how telomeres shorten with each cell division, leading to aging and cellular senescence. Dr. Andrews emphasizes the importance of inducing telomerase to potentially reverse aging and shares insights from his research on telomerase inducers. He also addresses the challenges in longevity research, the relationship between telomeres and the hallmarks of aging, and the potential of gene therapy. The conversation concludes with a discussion on lifestyle factors that can influence aging and the future of aging research. Learn more about Dr. Bill Andrews: https://sierrasci.com/dr-bill-andrews/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/
Amelie started out in the biology department at Reed because she wanted to study bacteria and living things, but then she got a chance to start learning from the biochemists on the faculty. They helped her build the bridge from chemistry to life, which led her to switch her major from biology to biochemistry and molecular biology. Amelie was also the second student producer for Burn Your Draft, working with us from 2021–22, and it was a delight to get to talk to her. Reed community members can read Amelie's thesis, “MntR: The Mastermind of Manganese Ion Homeostasis” online in the Electronic Theses Archive: https://rdc.reed.edu/i/9e05e465-0d21-4fb0-9de1-e6d4d2bf1349 Explore more interviews with Reed College alumni on our website: reed.edu/burnyourdraft
In this episode, we are joined by Dr. Kristy McAndrew from Mississippi State University. Dr. McAndrew will walk us through the ins and outs of Brown spot needle blight, a fungal disease that infects pine needles, leading to premature needle loss, stunted growth, and long-term stress that increases a tree's vulnerability to other pests and pathogens, and provide an update on Emerald Ash Borer presence in the region. Dr. McAndrew is a forest health specialist at Mississippi State University in the Forestry Department. Kristy has a Bachelor of Science in Forestry and a Bachelor of Science in Fisheries & Wildlife, both from the University of Missouri in Columbia, MO, and also completed a Master's and PhD at Mississippi State University in the Department of Biochemistry, Molecular Biology, Entomology, and Plant Pathology. For more on brown spot needle blight, see this recent article and publication from the Arkansas Division of Agriculture. www.uaex.uada.edu/media-resources/news/2025/august/08-18-2025-ark-UAM-needle-blight.aspx If you have questions, feel free to contact us at timberuniversity@gmail.com
In this episode of Speaking of Mol Bio, host Steve Lewis speaks with Dr. Melissa Wu, co-founder and CEO of Seeding Labs, a nonprofit that's redefining global scientific access. Dr. Wu shares the inspiring story of how Seeding Labs helps institutions in developing nations build research infrastructure by redistributing surplus laboratory equipment from partners like Thermo Fisher Scientific.With an innovative model that connects equipment donors in the global North with universities and institutes across Africa, Asia, and Latin America, Seeding Labs enables groundbreaking science in places where opportunity is limited but talent is abundant. Dr. Wu highlights examples like the Malawi University of Science and Technology, whose graduates are now staffing the country's first hospital microbiology labs, and a Beninese research team using donated PCR equipment to improve the yield of indigenous crops like the miracle berry.More than a logistics operation, Seeding Labs is also fostering scientific networks, reversing brain drain, and giving researchers confidence, courage, and agency. Dr. Wu offers a compelling vision of an equitable global scientific ecosystem, and shares how listeners can get involved—whether by donating equipment, funds, or simply spreading the word. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague. Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.
Guest: Paola Marignani, PhD, EMBA While smoking remains a key risk factor for lung cancer, up to 25 percent of cases occur in people who have never smoked, leaving significant gaps in our understanding of causation and diagnostics. Dr. Paola Marignani explores emerging discoveries in gene variants unique to never-smokers, uncovered through single-cell RNA sequencing and machine learning. Dr. Marignani is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University in Halifax, Novia Scotia, and she spoke about this topic at the 2025 World Conference on Lung Cancer.
Guest: Paola Marignani, PhD, EMBA While smoking remains a key risk factor for lung cancer, up to 25 percent of cases occur in people who have never smoked, leaving significant gaps in our understanding of causation and diagnostics. Dr. Paola Marignani explores emerging discoveries in gene variants unique to never-smokers, uncovered through single-cell RNA sequencing and machine learning. Dr. Marignani is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University in Halifax, Novia Scotia, and she spoke about this topic at the 2025 World Conference on Lung Cancer.
This week, we have Prof. John Beckett Wallingford to discuss the current landscape of federal science funding, and the importance of science in American industry and society. We set the scene with a reading of The Polio Vaccine, Chatham, Virginia, 1964, by Claudia Emerson. John Beckett Wallingford is a developmental biologist with three decades of experience. He is the Mr. and Mrs. Robert P. Doherty Jr. Regents Chair in Molecular Biology and a Professor in the Dept. of Molecular Biosciences at the University of Texas at Austin. Since 2003, his laboratory has sought to understand how form and function arise in embryos using advanced microscopy, systems biology, and biomechanics. Wallingford's research explores animal models and collaborates with human geneticists to understand human birth defects. He is writing a forthcoming book about embryos: In the Beginning.
Guest: Paola Marignani, PhD, EMBA Single-cell RNA sequencing is transforming our understanding of tumor heterogeneity in primary lung cancers by offering insights far beyond traditional bulk sequencing. In this program, Dr. Paola Marignani explores how advanced machine learning enables faster, more precise profiling of genetic diversity, predictive modeling for recurrence and drug resistance, and personalized treatment strategies. Dr. Marignani is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University in Halifax, Novia Scotia, and she spoke about this topic at the 2025 World Conference on Lung Cancer.
Guest: Paola Marignani, PhD, EMBA Single-cell RNA sequencing is transforming our understanding of tumor heterogeneity in primary lung cancers by offering insights far beyond traditional bulk sequencing. In this program, Dr. Paola Marignani explores how advanced machine learning enables faster, more precise profiling of genetic diversity, predictive modeling for recurrence and drug resistance, and personalized treatment strategies. Dr. Marignani is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University in Halifax, Novia Scotia, and she spoke about this topic at the 2025 World Conference on Lung Cancer.
In her keynote address to the IIEA, Dr Caoimhe Archibald MLA, Minister for the Economy in Northern Ireland, discusses economic opportunities for Northern Ireland in the context of constitutional change and her priorities in her current role. Dr Caoimhe Archibald MLA was appointed Minister for the Economy in the Northern Ireland Executive in February 2025. Previously, she served as Finance Minister from February 2024. Minister Archibald graduated from Queen's University, Belfast with a BSc in Molecular Biology and a PhD by research with a Department of Agriculture and Rural Development studentship. She also completed a Postgraduate diploma in Management & Corporate Governance at Ulster University. Minister Archibald was elected as an MLA for East Derry in May 2016, re-elected in March 2017, and again in May 2022. She is formerly Chair of the Assembly's Agriculture, Environment and Rural Affairs, and Economy committees. Prior to being elected in May 2016, she worked for almost a decade in applied horticulture and plant pathology research including on collaborative EU funded projects.
Looking for more information on this topic? Check out the Physiology of the Renal Tubular System brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts. It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks. After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.
In this conversation, Jared Vagy and Joe Manoles discuss the concepts of motor learning and motor control, particularly in the context of climbing. They explore key terminology, the stages of motor learning, and practical applications for climbers. The discussion also delves into personal challenges faced by climbers, types of practice and feedback, and the importance of understanding individual learning styles. The conversation emphasizes the significance of feedback mechanisms and learning strategies in improving climbing performance. Joe Manoles's Bio Dr. Joe Manoles PT, DPT is a healthcare professional in Bend, Oregon specializing in the treatment, recovery, and performance of climbers and mountain athletes. His care is characterized by his compassion, attention to detail, and dedication to holistic care. He believes strongly in the core pillars of health as a need for all human beings and their direct influence on our experience on Earth. In order to understand the complexity of health systems, Joe received a B.S in Biochemistry and Molecular Biology with a minor in Microbiology. He continued his education at Oregon State University-Cascades receiving his Doctorate of Physical Therapy and has sought out continuing educational mentorship and coursework through a variety of trusted resources in the climbing community including The Climbing Doctor, The Climb Clinic, and Camp 4 Human Performance. These days, if he isn't working on his new business Dissonance Performance and Physical Therapy, he is spending time with his spouse Taylor Manoles and their 4 year-old border collie Finn, climbing, snowboarding, and exploring the breathtaking beauty of central Oregon. Chapters 00:00 Introduction to Motor Learning and Control 02:54 Understanding Key Terminology 06:00 Stages of Motor Learning in Climbing 08:45 Applying Motor Learning to Climbing Techniques 12:06 Overcoming Challenges in Climbing Skills 14:58 Types of Practice and Feedback in Climbing 18:02 The Role of Feedback in Skill Development 21:09 Conclusion and Summary of Key Concepts 24:41 Exploring Climbing Preferences and Techniques 27:03 The Learning Process in Climbing 30:13 Feedback Mechanisms in Climbing 35:03 Error-Driven vs. Errorless Learning 39:23 Guided vs. Discovery Learning 40:38 Understanding Bandwidth in Feedback 42:13 Final Thoughts on Motor Learning in Climbing Links and Resources for This Episode:
Tonight at 8:30pm CST, on the Flyover Conservatives show we are tackling the most important things going on RIGHT NOW from a Conservative Christian perspective! Tonight at 8:30pm CST, on the Flyover Conservatives show we are tackling the most important things going on RIGHT NOW from a Conservative Christian perspective! TO WATCH ALL FLYOVER CONTENT: www.theflyoverapp.comTO WATCH ALL FLYOVER CONTENT: www.theflyoverapp.comFollow and Subscribe on YouTube: https://www.youtube.com/@TheFlyoverConservativesShowFollow and Subscribe on YouTube: https://www.youtube.com/@TheFlyoverConservativesShowhttps://www.youtube.com/@TheFlyoverConservativesShowTo Schedule A Time To Talk To Dr. Dr. Kirk Elliott Go To To Schedule A Time To Talk To Dr. Dr. Kirk Elliott Go To ▶ https://flyovergold.com▶ https://flyovergold.comOr Call 720-605-3900 Or Call 720-605-3900 ► Receive your FREE 52 Date Night Ideas Playbook to make date night more exciting, go to www.prosperousmarriage.com► Receive your FREE 52 Date Night Ideas Playbook to make date night more exciting, go to www.prosperousmarriage.comDr. Troy Spurrill is the founder and CEO of Synapse Center for Health and Healing. He started Synapse over 26 years ago with a vision to bring an integrative approach to healthcare through functional medicine, making Synapse an internationally known center for true health.Dr. Troy Spurrill is the founder and CEO of Synapse Center for Health and Healing. He started Synapse over 26 years ago with a vision to bring an integrative approach to healthcare through functional medicine, making Synapse an internationally known center for true health.He received a Bachelor's of Science in Molecular Biology from the University of Manitoba, and a Doctorate of Chiropractic from Northwestern Health Sciences University. He has extensive training in Functional Neurology, Nutrition, and Applied Kinesiology. Dr. Troy is an author and international lecturer on wellness and brain based healing. He received a Bachelor's of Science in Molecular Biology from the University of Manitoba, and a Doctorate of Chiropractic from Northwestern Health Sciences University. He has extensive training in Functional Neurology, NutSend us a message... we can't reply, but we read them all!Support the show► ReAwaken America- text the word FLYOVER to 918-851-0102 (Message and data rates may apply. Terms/privacy: 40509-info.com) ► Kirk Elliott PHD - http://FlyoverGold.com ► My Pillow - https://MyPillow.com/Flyover ► ALL LINKS: https://sociatap.com/FlyoverConservatives
Why are some people straight while others are gay or bisexual? What determines our sexual orientation anyway? Today, we're going to be diving into what we've learned about the biological origins of our sexuality from decades of scientific research. As you'll see, there's not a simple and easy story—it doesn't boil down to something like a “gay gene.” It's way more complex than that! I am joined once again by Nathan Lents, a Professor of Biology at John Jay College, where he is the director of the Cell and Molecular Biology program. His research lab studies human genetic evolution and forensic DNA technology. He also writes popular science articles and is the author of the new book The Sexual Evolution: How 500 Millions Years of Sex, Gender, and Mating Shape Modern Relationships. Some of the specific topics we explore include: Is same-sex attraction genetic? How can two people who share 100% of the same DNA have different sexual orientations? When researchers are studying sexual orientation, should they be looking at attraction, identity, behavior, or all of the above? Why is having more older brothers linked to greater odds of homosexuality in men? What other biological factors are associated with sexual orientation? You can check out Nathan’s website to learn more about his work. Got a sex question? Send me a podcast voicemail to have it answered on a future episode at speakpipe.com/sexandpsychology. *** Thank you to our sponsors! Load Boost is a supplement designed to improve the taste, volume, and overall health of your semen. If you want to elevate your sexual performance, check out Load Boost from VB Health. Visit loadboost.com to learn more and save 10% with code JUSTIN. The Kinsey Institute at Indiana University has been a trusted source for scientific knowledge and research on critical issues in sexuality, gender, and reproduction for over 75 years. Be sure to register for the Sex and Aging Symposium, which will take place on October 4, 2025. *** Want to learn more about Sex and Psychology? Click here for previous articles or follow the blog on Facebook, Twitter, or Bluesky to receive updates. You can also follow Dr. Lehmiller on YouTube and Instagram. Listen and stream all episodes on Apple, Spotify, Google, or Amazon. Subscribe to automatically receive new episodes and please rate and review the podcast! Credits: Precision Podcasting (Podcast editing) and Shutterstock/Florian (Music). Image created with Canva; photos used with permission of guest.
Dr. Jeff Gross — Board-certified neurological surgeon, biochemist, biohacker, founder of Celebrate Regenerative Medicine, and longevity/biohacking consultant based in Las Vegas & Southern California. Medical & Health Longevity Background: Dr. Gross trained at UC Berkeley (Biochemistry & Molecular Biology), George Washington University School of Medicine, UC Irvine (Neurosurgery), and UNM (Spinal Biomechanics). He has decades of frontline experience in spine surgery, sports injuries, regenerative medicine, and now consults on biohacking and longevity. Biohacking & Longevity: Biohacking is essentially circles back to ancient wellness wisdom (eat well, sleep, exercise)—but enhanced by modern science (measuring phytonutrients, leveraging tech like red light, hyperbaric therapy, protein timing, etc). Emphasizes that “prevention” is still the number one defense against the four top causes of death in Western countries; early proactive screening and lifestyle habits remain critical. There is increasing crossover between “traditional medicine” and “naturopathic”/“functional” approaches—Dr. Gross sees this convergence as positive and overdue, but notes resistance still exists in mainstream medicine. Emerging Business Opportunities in the Wellness Space: IV centers, cryotherapy, and retail biohacking clinics (hyperbaric O2, red light therapy, peptides, weight loss clinics, etc.) are booming, especially in health-conscious cities. Low-barrier options: health coaching, nutrition consulting, affiliate/online influencer businesses—Dr. Gross notes people he knows personally earning seven figures as wellness affiliates. Innovations: Short-form EMS (electro-muscular stimulation) workouts, “blood flow restriction” exercise systems, and more. Cancer screening clinics: Now possible with advanced genomics and blood-testing—these are in demand but not widely available through traditional doctors/insurance, opening more avenues for direct-to-consumer providers. Supplementation & Biohacking Basics: “Non-negotiables” for almost everyone: Vitamin D3 (& often K2): Most people are deficient; optimal blood levels promote longevity, reduce inflammation, and lower all-cause mortality. Magnesium: Especially at night for recovery and cellular repair. Creatine: Improves muscle mass, heart health, and brain health; well correlated with longevity. Probiotics: Modern lifestyles make gut health challenging—good probiotic support is important. Nicotine: Can be a cognitive enhancer in low doses and proper delivery (gum/patch, NOT smoking)—but is highly addictive. Other Business/Money Ideas: Successful affiliate and influencer businesses for those passionate about health and wellness. Emphasizes supplement sales (with high trust and real value), personalized coaching, and education are evergreen opportunities. Industry Critique: Criticizes health insurance as a “legal mafia,” noting it often adds cost and hassle while limiting real preventive care. Encourages listeners to be their “own best advocate” for health—don't rely only on five-minute mainstream doctor visits. Connect with Dr. Jeff Gross: https://recellebrate.com/
This one's got it all: teeny tiny cellular factories, mitochondrial relevancy, what big smelly vats of poop have to do with curing cancer, how many trips to the sun your unravelled DNA could make, and mysteries of the brain. Dr. Raven The Science Maven has a background in molecular biology and a Ph.D in Science Communication, which she puts to work while Alie generally does her best to suppress high pitched noises of excitement. Learn to appreciate your proteins and pick up some noodle analogies while you're here. That's so Maven!Follow Raven on Instagram and BlueskyVisit Raven's website and YouTube channelA donation went to Project for AwesomeFull-length (*not* G-rated) Molecular Biology episode + tons of science linksMore kid-friendly Smologies episodes!Become a patron of Ologies for as little as a buck a monthOlogiesMerch.com has hats, shirts, hoodies, totes!Follow Ologies on Instagram and BlueskyFollow Alie Ward on Instagram and TikTokSound editing by Mercedes Maitland of Maitland Audio Productions, Jarrett Sleeper of MindJam Media, and Steven Ray MorrisMade possible by work from Noel Dilworth, Susan Hale, Jacob Chaffee, Kelly R. Dwyer, Aveline Malek and Erin TalbertSmologies theme song by Harold Malcolm
In this Mol Bio Minutes mini-episode, Thermo Fisher Scientific's Agnė Žiupkaitė takes listeners on a journey through the evolving world of RNA assay development—focusing specifically on 1-Step RT-qPCR. She outlines the critical considerations for assay developers, including enzyme speed, robustness, and the growing demand for customizable reagents that meet both technical and regulatory needs.Highlighting Thermo Fisher's SuperScript reverse transcriptase family—particularly the Lyo-ready SuperScript III Flash RT—Agnė explains how innovations in enzyme design have broken past bottlenecks in assay workflow, enabling reverse transcription in under a minute. She also explores the power of customization, from labeling and fill formats to enzyme formulation changes and glycerol-free options that support microfluidic platforms and lyophilization.Agnė offers practical insight into how raw material suppliers can serve as collaborative partners, not just vendors. She emphasizes the importance of commercial rights, scalability, and regulatory readiness when sourcing components for commercial assay kits. Whether you're an OEM kit developer or a scientist building the next molecular breakthrough, this episode is packed with actionable insights to improve efficiency, reliability, and speed.Helpful resource links mentioned in this episode:Learn more about raw materials for molecular diagnosticsOrder Lyo-ready SuperScript III Flash TranscriptaseVisit this page to expand your knowledge of reverse transcription Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague. Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.
Are human beings made for monogamy or non-monogamy? This is a popular subject of debate. While some argue that humans evolved for monogamy in order to ensure parental investment in our offspring, others argue that humans evolved to be non-monogamous because it increases the odds of reproductive success and genetic diversity in our species. So which is it? That's what we're going to be talking about today. I am joined by Nathan Lents, a Professor of Biology at John Jay College, where he is the director of the Cell and Molecular Biology program. His research lab studies human genetic evolution and forensic DNA technology. He also writes popular science articles and is the author of the new book The Sexual Evolution: How 500 Millions Years of Sex, Gender, and Mating Shape Modern Relationships. Some of the specific topics we explore include: What’s the difference between social monogamy and sexual monogamy? How common are social and sexual monogamy in both humans and animals, and how often do they overlap? Can research on other primates shed light on how human mating strategies evolved? Can someone’s brain chemistry predispose them to being monogamous or non-monogamous? You can check out Nathan’s website to learn more about his work. Got a sex question? Send me a podcast voicemail to have it answered on a future episode at speakpipe.com/sexandpsychology. *** Thank you to our sponsors! Load Boost is a supplement designed to improve the taste, volume, and overall health of your semen. If you want to elevate your sexual performance, check out Load Boost from VB Health. Visit loadboost.com to learn more and save 10% with code JUSTIN. Passionate about building a career in sexuality? Check out the Sexual Health Alliance. With SHA, you’ll connect with world-class experts and join an engaged community of sexuality professionals from around the world. Visit SexualHealthAlliance.com and start building the sexuality career of your dreams today. *** Want to learn more about Sex and Psychology? Click here for previous articles or follow the blog on Facebook, Twitter, or Bluesky to receive updates. You can also follow Dr. Lehmiller on YouTube and Instagram. Listen and stream all episodes on Apple, Spotify, Google, or Amazon. Subscribe to automatically receive new episodes and please rate and review the podcast! Credits: Precision Podcasting (Podcast editing) and Shutterstock/Florian (Music). Image created with Canva; photos used with permission of guest.
In Episode 92, Althea talks with Leonardo Feletto. Leo has a PhD in Molecular Biology and is now a science teacher. But most important for this particular episode, Leo is a science communicator.
The biotech at the fingertips of farmers is super exciting. But is regulation keeping pace with scientific leaps?Biotech like gene editing has the potential to revolutionise the industry - by not only enhancing crop yields, but supporting sustainable farming practices, and helping address global climate change and food security. Michael Leader's job with Bayer is an interesting one - he's the bridge connecting the science labs and the regulators; translating complex new biotech innovation to policy makers. In this chat Michael discusses the legislative hurdles for biotech, use of AI in new crop protection technologies, the new biotech in the pipeline for farmers, and the careers in agriculture that go beyond the paddock. Michael Leader is the Regulatory Policy & Stakeholder Engagement Manager for the Asia region, for Bayer Crop Science Australia. TakeawaysMichael's background in law and molecular biology, and now working in regulatory policy in agricultureThe opportunities in the Asian region for applying biotech, with policy stagnating ag innovation tools to dateBiotechnology has evolved significantly over the past 30 years but GM breeding typically takes 16 years to get to market and $100m in research and regulatory costsActivism continues to challenge the acceptance of biotechnologyThere is a need for regulatory reform to accommodate new technologiesThe lack of distinction between the definitions of 'genome editing' and 'genetically modified' is inhibiting workable regulatory frameworkFuture agricultural innovations could address climate change and food securityBayer is proactive with transparency, showing their biotech studies online and using Open Labs 360, a self-guided virtual reality tour of labs and fields to understand regulatory and safety dataChapters03:06 The Intersection of Law and Molecular Biology05:58 Career Journey in Regulatory Policy09:03 Current Work and Responsibilities at Bayer12:08 Opportunities in Asian Agriculture17:57 Challenges and Misconceptions in Biotechnology23:55 Regulatory Hurdles in Biotechnology26:58 Future of Agricultural InnovationLinks:Learn more about Bayer Australia and New Zealand, follow them on Facebook, Instagram and LinkedInMore episodes at Humans of AgricultureThis is a sponsored series in partnership with Bayer Crop Science Australia, showcasing Bayer's commitment to innovation; supporting Aussie agriculture and backing rural communities.
Aanya discusses her project, "Sharing the Joys of Cultural Diversity," which focused on fostering understanding and appreciation of cultural differences among children in her community. Aanya highlights two key components of her project: facilitating discussions about cultural identity in local schools and creating a children's book that details her own experiences as an immigrant from India. She reflects on her personal struggles with cultural acceptance and the importance of embracing one's identity. Join us as Aanya shares her insights and the impact of her work in promoting cultural diversity. More about Annya: Aanya is a sophomore at Princeton University studying Molecular Biology on the pre medicine track. For her Gold Award, Aanya created a cultural education and appreciation initiative in her community to encourage children to develop their global literacy and spark their love for diversity. Aanya published a children's book, Samosas with Saanvi, to share how she grew to love her cultural identity, capture the joys of cultural diversity, and portray the emotional journey behind acceptance. The mission of her project was to bridge the cultural literacy gap she noticed in her community, allow children to discover their own cultural identities, and foster meaningful community connections. At Princeton, Aanya is involved in The Daily Princetonian Podcast and STEM Research Journalism teams, the Undergraduate Student Government Mental Health and Diversity, Equity, and Inclusion Committees, and the Council on Science & Technology Student Advisory Board. She is very interested in scientific and medical research, working with the IMDEA Materials Institute to learn more about biomaterials and regenerative medicine, as well as Fundação Oswaldo Cruz in virology and immunology. She loves to continue sharing her book and cultural story with family, friends, and community members. In her freetime, you may find her reading the newest fantasy or mystery novel, singing karaoke with her little sister, or playing with her shih tzu poodle Daisy. https://www.amazon.com/Samosas-Saanvi-Aanya-Kasera/dp/B0CCCKNZW3
Why is fentanyl a thing in North America, but not other places? Guest: Dr Jonathan Culkins, Professor Of Operations Research And Public Policy, Carnegie Mellon University How will wildfire smoke affect certain people more than others in the future? Guest: Dr Emilia Lim, Faculty of Medicine in the Department of Biochemistry and Molecular Biology, UBC Summer isn't over but kids are stressed about school Guest: Dr. Daniel Chorney, psychologist specializing in services for children and adolescents. Is burnout the new normal? Guest: Kadine Cooper, Career and life coach, facilitator and speaker. New data shows people are leaving BC in big numbers Guest: Jairo Yunis, former policy analyst at the Fraser Institute Learn more about your ad choices. Visit megaphone.fm/adchoices
How will wildfire smoke affect certain people more than others in the future? Guest: Dr. Emilia Lim, Faculty of Medicine in the Department of Biochemistry and Molecular Biology, UBC Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode, host Steve Lewis sits down with Giovanna Prout, President and CEO of Scale Biosciences, to explore how Scale is pushing the boundaries of single-cell omics. With a career that spans roles with big players and entrepreneurial ventures, Giovanna brings a unique perspective to the world of genomics innovation.Giovanna dives into Scale's patented Quantum Barcoding technology—a high-throughput, combinatorial indexing approach that allows researchers to process millions of cells and thousands of samples simultaneously, all without the need for specialized instrumentation. She explains how this flexible, automation-friendly platform is opening doors for AI-driven data modeling, large-scale drug screening, and highly diverse patient cohort studies.Beyond the science, Giovanna reflects on her leadership journey, emphasizing persistence, servant leadership, and a passion for making a difference in life sciences. She also shares the vision behind the 100 Million Cell Initiative, a bold collaboration that empowers scientists to dream big without constraints. For early-career scientists, Giovanna offers candid advice on working hard, staying curious, and believing in the impact of their work. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague. Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.
Looking for more information on this topic? Check out the Congenital Adrenal Hyperplasia brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts. It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks. After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.
Looking for more information on this topic? Check out the Thrombotic Disorders: Foundations and Frameworks brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts. It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks. After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.
Dr. Ganesh Anand is an Associate Professor of Chemistry as well as Biochemistry and Molecular Biology at The Pennsylvania State University (or Penn State University) at the University Park campus. He is also an elected Board Member of the International Society for Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS). Research in Ganesh's lab examines molecular switches. He wants to know how molecules interact with one another and how they switch from one state to another. These tiny molecular switches act almost like electrical switches turning on and off the functions of different molecules. He also does research on viruses and how they change shape to infect their hosts. Beyond his scientific interests, Ganesh has also been passionate about music for as long as he can remember. He takes voice lessons now and enjoys singing in choirs in his free time. He received his bachelor's degree in pharmacy and his master's degree in biological sciences from Birla Institute of Technology and Science in India. Next, Ganesh attended Rutgers University where he earned his PhD in biochemistry. Afterwards, he conducted postdoctoral research as a Howard Hughes Medical Institute Research Fellow at the University of California San Diego. Ganesh served on the faculty in the Department of Biological Sciences at the National University of Singapore for over a decade before accepting a faculty position at Penn State where he is today. His lab is recognized as a Waters World Center of Innovation in Hydrogen/Deuterium Exchange Mass Spectrometry. Ganesh is founding member and former Director of the Singapore National Laboratory for Mass Spectrometry (SingMass) and the former Vice President of the Singapore Society for Mass Spectrometry. In this interview, he shares more about his life and science.
Presenter, Dr. Aigerim Bijelic, holds a Ph.D. in Cell and Molecular Biology and a Master's in Nutrition and Functional Medicine. She uses evidence-based, root-cause approaches and believes bodies have an innate ability to heal when given the right support. Her goal is to help create that environment for her clients. Then the second half of the workshop Bev & Paul teach you the Bio-Touch sets that that you can use to work with folks on how to help with any weight loss program.
Send us a textHow brain synapses work and fuel themselves with fat.Episode Summary: Dr. Timothy Ryan talks about the high energy costs of synapses, the role of mitochondria and glycolysis, and challenge the long-held view that the brain relies solely on glucose by discussing new evidence that neurons burn fats from lipid droplets for fuel, especially during activity. The talk touches on metabolic flexibility, links to epilepsy treatments like ketogenic diets, neurodegenerative diseases, and future research on brain energy sources.About the guest: Timothy Ryan, PhD is a professor of biochemistry at Cornell University. His research focuses on the molecular mechanisms of synaptic transmission, particularly vesicle recycling and the bioenergetics that power neural communication. Discussion Points:Synapses are tiny structures with ~100 vesicles per site (on average), converting electrical signals to chemical ones.Brain tissue is energy-hungry due to trillions of synapses (in humans), relying on local mitochondria (present in only ~half of synapses) and glycolysis.Vesicles use proton pumps and transporters to concentrate neurotransmitters, requiring ATP to maintain gradients.Neurons are metabolically fragile; cutting fuel supply quickly impairs synapses.Dogma held brains don't burn fats, but new work shows neurons form lipid droplets (fat stores) that are invisible because constantly used for energy via beta-oxidation.Silencing neurons builds lipid droplets like resting muscle; activity speeds their breakdown, indicating demand-driven fat use.Inhibiting neuron-specific fat-processing enzymes accumulates droplets and induces torpor (hibernation-like state) in animals, signaling metabolic stress.Ketogenic diets aid epilepsy by shifting to ketones; fats may explain this, with potential ties to aging and neurodegeneration like Alzheimer's.Brain may be a "hybrid" fuel user (glucose + fats), with open questions on fat sources and roles in cognition or disease protection.Related episode:M&M 158: Ketosis & Ketogenic Diet: Brain & Mental Health, Metabolism, Diet & Exercise, Cancer, Diabetes | Dominic D'Agostino*Not medical advice.Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts
Jerneja Tomsic is a rebellious, outspoken gal (thank goodness) who carries a PhD in Molecular Biology. Being from Slovenia (as is Melania Trump), she knows about socialism... down to the untruths of science paradigms because she is in that world, is now awake and researches. From the lies of PCR tests being effective in diagnosing Co*v*d down to the truth of DNA/double helix, cancer, mammograms, viruses and bacteria.For the "Just Be Practice," Jerneja highlights how fear is the real virus.References for the show:https://viroliegy.comConversation on breast health:https://odysee.com/@Dawn-Lester:3/Conversation-with-Robyn---Jerneja:eLinks to Jerneja:Her Rumble channel: https://rumble.com/user/Jerneja18Chat with Kevin Corbett on PCR tests for The End of COVID project:https://odysee.com/@TheEndOfCovid:3/20230706-TEOC-TEOC-SESSION-The-PCR-Tests--Dr--Jerneja-Tomsic--Dr--Kevin-Corbett-MULTICAM-CUT-2-mov-by-NA:bThe Scientific Method:https://rumble.com/v59dcal-mwk-science-1-the-scientific-method-jerneja-tomsic.htmlPeer Review:https://rumble.com/v5b8wcd-mwk-science-2-peer-review-jerneja-tomsic.html*Host Eden Koz is a soul realignment specialist utilizing such gifts as psychological empathy, intuition, psychic ability, mediumship, meditation, mindset shift, Reiki, dimensional and galactic healing, to name a few. She can also perform a spiritual Co#id Vac+ Healing as well as remote & face-to-face sessions with individuals and groups. Contact info for Eden Koz / Just Be®, LLC:Website: EdenJustBe.com Socials: Insta, FB, FB (Just Be), LinkedIn Just Be~Spiritual BOOM Podcast can be found on the audio directories: Apple Podcasts, Spotify, Amazon Music, Stitcher, iHeart Radio, TuneIn+Alexa, ...
Looking for more information on this topic? Check out the Physiology of Diuretics brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts. It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks. After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.
In this solo episode of Vegan Boss Radio, I dive into the narratives of ex-vegans who've become outspoken anti-vegans. While I won't name names, I break down some of the common claims they're making, why the science doesn't support them, and how misinformation about plant-based diets continues to spread online. We'll look at: The recurring myths about plant based nutrition Why their symptoms likely weren't caused by a balanced vegan diet How extreme or overly restrictive versions of veganism often lead to burnout I wrap up with an important reminder: if you're unsure whether you're meeting your nutrient needs, or you're dealing with any lingering health issues, it's essential to work with a qualified plant-based health professional. Don't let misinformation derail your progress.
Synopsis: What do courtroom litigation, computational biology, and fibrosis drug development have in common? In this episode of Biotech 2050, host Alok Tayi speaks with Ahmed Mousa, CEO of Vicore Pharma, to explore his unconventional journey from biotech law to the C-suite. Ahmed shares how Vicore is advancing a first-in-class therapy targeting the angiotensin II type 2 receptor to treat idiopathic pulmonary fibrosis (IPF)—a devastating disease with limited options and poor survival. The conversation dives into how AI is reshaping drug discovery, the promise of precision in early-stage candidate design, and the regulatory and data challenges biotech must overcome. Ahmed also reflects on leading a Swedish-listed biotech as an American CEO, and how a patient-first mission continues to fuel bold innovation across continents. Biography: Ahmed Mousa is the Chief Executive Officer of Vicore Pharma (VICO.ST), where he leads the company's mission to advance angiotensin II type 2 receptor agonists for the treatment of idiopathic pulmonary fibrosis and other serious diseases. Under his leadership, Vicore continues to expand its clinical pipeline and global presence in respiratory and fibrotic diseases. Previously, Ahmed served as Senior Vice President, Chief Business Officer, and General Counsel at Pieris Pharmaceuticals (PIRS). In this role, he was the site head for the company's Boston office and oversaw business development, portfolio strategy, centralized project leadership, and quality assurance. He also led Pieris' legal and intellectual property functions, including licensing, corporate governance, and management of the company's global patent portfolio. Before joining Pieris, Ahmed was an attorney at Covington & Burling LLP, where he advised pharmaceutical and biotechnology companies on a range of regulatory and intellectual property matters. He also served as a law clerk for the U.S. Court of Appeals for the Third Circuit and began his legal career as an IP associate at Kirkland & Ellis LLP. Ahmed holds dual undergraduate degrees in Molecular Biology and Government from Cornell University, a Master's in Biotechnology from Johns Hopkins University, and a J.D. with honors from Georgetown Law, where he was Editor-in-Chief of the Georgetown Journal of International Law.
In this episode, Dr Joost Groen, a clinical biochemist at the University Medical Center Groningen, and Dr Matt Gentry, Professor & Chair of Biochemistry & Molecular Biology in the College of Medicine at University of Florida, join Rodrigo and Silvia to discuss new insights, AI, cancer metabolism and some of their favourite papers on Glycogen Storage Disorders. Authors opinions are their own and do not represent their institutions. GSD episode papers: Brain glycogen serves as a critical glucosamine cache required for protein glycosylation. Sun et al A machine learning model accurately identifies glycogen storage disease Ia patients based on plasma acylcarnitine profiles. Groen et al Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders. Ullman et al Repurposing SGLT2 inhibitors: Treatment of renal proximal tubulopathy in Fanconi-Bickel syndrome with empagliflozin. Overduin et al Gross-Valle The relation between dietary polysaccharide intake and urinary excretion of tetraglucoside. Gross-Valle et al Glycogen drives tumour initiation and progression in lung adenocarcinoma. Clarke HA et al Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis. Conroy et al In situ mass spectrometry imaging reveals heterogeneous glycogen stores in human normal and cancerous tissues. Young et al Glycogen accumulation modulates life span in a mouse model of amyotrophic lateral sclerosis. Brewer et al Dynamics of cognitive variability with age and its genetic underpinning in NIHR BioResource Genes and Cognition cohort participants. Rahman MS et al Neurological glycogen storage diseases and emerging therapeutics Colpaert et al
Dr. Jessica Rose is an artist, musician, mathematician, professional surfer, biologist, science researcher & data analysis. Dr. Rose has a Post Doc in Biochemistry at Technion Institute of Technology, Post Doc in Molecular Biology at Hebrew University of Jerusalem, PhD in Computational Biology at Bar-Ilan University, Master's in Medicine (Immunology) at Memorial University of Newfoundland, and BSc in Applied Mathematics at Memorial University of Newfoundland.DR. JESSICA ROSE:Twitter: https://twitter.com/JesslovesMJKSubStack: https://jessicar.substack.com/YouTube: https://www.youtube.com/channel/UC0EhWf2Vswdg7DwKKKZ34ngTHE RIPPLE EFFECT PODCAST:WEBSITE: http://TheRippleEffectPodcast.comWebsite Host & Video Distributor: https://ContentSafe.co/SUPPORT:PATREON: https://www.patreon.com/TheRippleEffectPodcastPayPal: https://www.PayPal.com/paypalme/RvTheory6VENMO: https://venmo.com/code?user_id=3625073915201071418&created=1663262894MERCH Store: http://www.TheRippleEffectPodcastMerch.comMUSIC: https://music.apple.com/us/album/the-ripple-effect-ep/1057436436SPONSORS:OPUS A.I. Clip Creator: https://www.opus.pro/?via=RickyVarandasUniversity of Reason-Autonomy: https://www.universityofreason.com/a/2147825829/ouiRXFoL WATCH:RUMBLE: https://rumble.com/c/therippleeffectpodcastBANNED.VIDEO: https://banned.video/channel/the-ripple-effect-podcastOFFICIAL YOUTUBE: https://www.youtube.com/@TheRippleEffectPodcastOFFICIALYOUTUBE CLIPS CHANNEL: https://www.youtube.com/@RickyVarandasTikTok: https://www.tiktok.com/@ricky.varandasLISTEN:SPOTIFY: https://open.spotify.com/show/4lpFhHI6CqdZKW0QDyOicJiTUNES: http://apple.co/1xjWmlFPodOmatic: https://www.podomatic.com/podcasts/rvtheory6CONNECT:TeleGram: https://t.me/TREpodcastX: https://x.com/RvTheory6IG: https://www.instagram.com/rvtheory6/ FB: https://www.facebook.com/TheRippleEffectPodcast/THE UNION OF THE UNWANTED: https://linktr.ee/TheUnionOfTheUnwanted
In this episode of the Epigenetics Podcast, we talked with Sarah Teichmann from the University of Cambridge about the Human Cell Atlas. In the Interview we explore Sarah Teichmann's impressive career trajectory, covering her current role as Chair of Stem Cell Medicine at the Cambridge Stem Cell Institute and Vice President of Translational Research at GlaxoSmithKline. Professor Teichmann explains her unique dual appointments, a rare arrangement that allows her to bridge academia and industry effectively. As the conversation shifts focus to computational biology, she takes us on a historical journey from her PhD work at the MRC Laboratory of Molecular Biology to the present advancements driven by next-generation sequencing and artificial intelligence methods. Professor Teichmann emphasizes that the landscape of biological research has evolved significantly, particularly in the realm of data-driven methodologies. The conversation then transitions seamlessly into her pivotal role in advancing single-cell genomics, where she discusses the motivation behind using single-cell RNA sequencing methods in her research on T cells. This technique offered unmatched insights compared to bulk sequencing techniques, allowing for a more detailed understanding of cell states and their complex interactions within tissues. A highlight of the episode is Professor Teichmann's insights on the Human Cell Atlas project, which she co-founded in 2017. She elaborates on the ambitious vision to map all human cells, likening the endeavor to the Human Genome Project. Through the atlas, researchers aim to create a detailed reference map that facilitates a deeper understanding of human health and disease. Professor Teichmann shares the collaborative efforts that led to its inception and the importance of international cooperation in scientific research. The discussion culminates with an exploration of the biggest scientific findings thus far from the Human Cell Atlas. Among the revelations, she notes the astounding complexity and diversity of cell types identified, particularly within the immune system, and the unexpected locations of certain cell types during human development. She also highlights significant discoveries related to COVID-19, demonstrating the immediate real-world impact of their work. References https://www.humancellatlas.org The Human Cell Atlas: towards a first draft atlas Kock, K. H., Tan, L. M., Han, K. Y., Ando, Y., Jevapatarakul, D., Chatterjee, A., Lin, Q. X. X., Buyamin, E. V., Sonthalia, R., Rajagopalan, D., Tomofuji, Y., Sankaran, S., Park, M. S., Abe, M., Chantaraamporn, J., Furukawa, S., Ghosh, S., Inoue, G., Kojima, M., Kouno, T., … Prabhakar, S. (2025). Asian diversity in human immune cells. Cell, 188(8), 2288–2306.e24. https://doi.org/10.1016/j.cell.2025.02.017 Related Episodes The Discovery of Genomic Imprinting (Azim Surani) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com
Dr. Jessica Rose is an artist, musician, mathematician, professional surfer, biologist, science researcher & data analysis. Dr. Rose has a Post Doc in Biochemistry at Technion Institute of Technology, Post Doc in Molecular Biology at Hebrew University of Jerusalem, PhD in Computational Biology at Bar-Ilan University, Master's in Medicine (Immunology) at Memorial University of Newfoundland, and BSc in Applied Mathematics at Memorial University of Newfoundland.DR. JESSICA ROSE:Twitter: https://twitter.com/JesslovesMJKSubStack: https://jessicar.substack.com/YouTube: https://www.youtube.com/channel/UC0EhWf2Vswdg7DwKKKZ34ngTHE RIPPLE EFFECT PODCAST:WEBSITE: http://TheRippleEffectPodcast.comWebsite Host & Video Distributor: https://ContentSafe.co/SUPPORT:PATREON: https://www.patreon.com/TheRippleEffectPodcastPayPal: https://www.PayPal.com/paypalme/RvTheory6VENMO: https://venmo.com/code?user_id=3625073915201071418&created=1663262894MERCH Store: http://www.TheRippleEffectPodcastMerch.comMUSIC: https://music.apple.com/us/album/the-ripple-effect-ep/1057436436SPONSORS:OPUS A.I. Clip Creator: https://www.opus.pro/?via=RickyVarandasUniversity of Reason-Autonomy: https://www.universityofreason.com/a/2147825829/ouiRXFoL WATCH:RUMBLE: https://rumble.com/c/therippleeffectpodcastBANNED.VIDEO: https://banned.video/channel/the-ripple-effect-podcastOFFICIAL YOUTUBE: https://www.youtube.com/@TheRippleEffectPodcastOFFICIALYOUTUBE CLIPS CHANNEL: https://www.youtube.com/@RickyVarandasTikTok: https://www.tiktok.com/@ricky.varandasLISTEN:SPOTIFY: https://open.spotify.com/show/4lpFhHI6CqdZKW0QDyOicJiTUNES: http://apple.co/1xjWmlFPodOmatic: https://www.podomatic.com/podcasts/rvtheory6CONNECT:TeleGram: https://t.me/TREpodcastX: https://x.com/RvTheory6IG: https://www.instagram.com/rvtheory6/ FB: https://www.facebook.com/TheRippleEffectPodcast/THE UNION OF THE UNWANTED: https://linktr.ee/TheUnionOfTheUnwanted
Send us a textHow our biological clocks shape biology from the molecular to behavioral level.Episode Summary: Dr. Joseph Takahashi discusses circadian rhythms, exploring their biological basis, from molecular mechanisms to their impact on metabolism and health; the discovery of circadian clock genes; role of the suprachiasmatic nucleus, and how light, feeding, and oxygen influence these rhythms. The conversation highlights practical implications, such as the effects of artificial light and meal timing on health, and touches on emerging research linking stronger circadian clocks to longevity.About the guest: Joseph Takahashi, PhD is a renowned neuroscientist at UT Southwestern Medical Center, where he leads research on circadian clock genes.Discussion Points:The suprachiasmatic nucleus in the hypothalamus acts as the brain's central clock, syncing with light via the retina.Key circadian genes like CLOCK and BMAL regulate thousands of genes, especially those involved in metabolism, impacting health outcomes.Internal desynchronization, when brain and organ clocks misalign (e.g., from eating at night), can lead to metabolic issues like pre-diabetes.In mice, eating at the right time (night for nocturnal animals) extends lifespan by up to 35% under caloric restriction, compared to 10% with spread-out feeding.Artificial light, especially blue light at night, disrupts melatonin and circadian rhythms, while natural sunlight supports healthy eye development.Melatonin, a darkness-signaling hormone, is best for resetting rhythms (e.g., jet lag) at low doses, not as a sedative, and U.S. supplements vary widely in quality.Oxygen-sensing proteins interact with circadian clock components, hinting at links between altitude, metabolism, and health.Learning and memory show diurnal variations, with better performance at certain times, influenced by circadian modulation of synaptic activity.A stronger circadian clock, created genetically in mice, led to 16% longer lifespan and resistance to weight gain (unpublished research).Related episode:M&M 202: Why Do Animals Sleep? | Vlad Vyazovskiy*Not medical advice.Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts
Send us a textCellular self-organization, cytoskeleton dynamics, and membrane wound healing.Episode Summary: Cell Biologist Dr. Bill Bement explains the dynamic world of the cell cortex, discussing how actin filaments and microtubules drive processes like cell division and wound healing through self-assembly and self-organization; energy dynamics of these processes; the role of rho GTPases in patterning; the implications for diseases such as cancer and muscular dystrophy, using vivid analogies and video demonstrations to make complex concepts accessible.About the guest: Bill Bement, PhD is a cell biology professor at the University of Wisconsin-Madison, where he has studied cellular processes for over 30 years. He leads a lab focused on the cell cortex, investigating cell division and repair. His work emphasizes self-organization and cytoskeletal dynamics, contributing to insights into diseases like muscular dystrophy.Discussion Points:The cell cortex, the outer layer of a cell, includes the plasma membrane & underlying proteins like actin & myosin, which enable dynamic shape changes.Actin filaments self-assemble without energy input, growing & shrinking to facilitate cell movement and division, while microtubules, stiffer hollow tubes, aid in chromosome separation.Self-organization in cells, driven by energy-dependent feedback loops, creates complex patterns like mitotic spindles.Cellular wound healing involves concentric rings of rho GTPases and actin, closing wounds rapidly, a process critical for surviving natural damage from mechanical stress or toxins.Energy costs of cytoskeletal rearrangements are significant but likely less than protein synthesis, though precise measurements remain challenging.Cancer metastasis may rely on enhanced cell repair, allowing metastatic cells to survive mechanical damage while squeezing through tissues.Muscular dystrophy involves excessive damage or impaired repair, highlighting the importance of cell repair mechanisms.Bement's lab is developing tools for synthetic self-organization, aiming to manipulate cellular processes to address repair deficits in diseases.Related episode:M&M 220: Cell Death, Oxidative Stress, PUFAs & Antioxidants | Pamela Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts
Welcome back to the WellFuel Podcast with your host, Isabel Smith!We're excited to bring you a truly special episode this week - one that's been long-awaited by our community. Isabel is opening up about her personal journey with Long COVID, Lyme, and co-infections, and the unconventional path she took to find relief.After her own battle with COVID-19 and a resurgence of chronic symptoms, Isabel teamed up with a specialist to explore a unique approach: using a nicotine patch to help reduce viral loads and free up ACE2 receptors. Whether you or someone you love is dealing with Long COVID, chronic illness, or just curious about innovative healing protocols, this episode is packed with valuable insights and real-life experience.Isabel's story is raw, honest, and full of hope. We hope it inspires you to keep searching for answers and reminds you that you're not alone in your healing journey.Tune in now to hear the full episode - and don't forget to share it with anyone who might benefit from Isabel's experience and insights!---------------------------EPISODE HIGHLIGHTS: The backstory of Isabel's struggle with Lyme and Long COVIDWhy she considered the nicotine patch protocol - and how it worksHonest reflections on the symptoms, challenges, and adjustments she faced along the wayThe supplements and strategies that supported her two-month journeyInsightful commentary on the results she achieved and what this could mean for others facing similar chronic conditions--------------------------CHAPTERS: 00:00 – Welcome to the WellFuel Podcast00:24 – My Journey with Lyme and Long COVID01:20 – The Nicotine Patch Protocol03:40 – Experiencing the Nicotine Patch04:53 – Symptom Log and Supplementation06:27 – Challenges and Adjustments10:06 – Final Thoughts and Future Plans-----------------------------HELPFUL DEFINITIONS: ACE2 Receptors: ACE2 is a protein on the surface of many cell types. It is an enzyme that generates small proteins – by cutting up the larger protein angiotensinogen – that then go on to regulate functions in the cell.Using the spike-like protein on its surface, the SARS-CoV-2 virus binds to ACE2 – like a key being inserted into a lock – prior to entry and infection of cells. Hence, ACE2 acts as a cellular doorway – a receptor – for the virus that causes COVID-19.Lumbrokinase: Lumbrokinase is known for its ability to dissolve fibrin, which is a crucial component of blood clots. This ability makes it potentially useful in preventing and treating conditions related to excessive blood clotting. Nattokinase: Nattokinase is an enzyme that's extracted from natto, a traditional Japanese food made from fermented soybeans. Nattokinase is particularly known for its potential effects on blood circulation and blood clots.The Krebs Cycle: The Krebs cycle is used by organisms that generate energy via respiration, either anaerobically or aerobically (organisms that ferment use different pathways).M-Spike Protein: The M-spike, also known as monoclonal protein or paraprotein, is a marker in blood tests that indicates the presence of abnormal plasma cells.HRV: HRV, or Heart Rate Variability, refers to the variation in time between heartbeats. ---------------------LEARN MORE: The WellFuel Podcast explores gut health, detox, hormones, mold, and more—hosted by Isabel Smith, MS, RD, CDN. Join Isabel as she shares her insights and chats with experts from across the wellness spectrum, to help support you on the path to health and wellness.Learn more about Isabel Smith Nutrition: Visit Our WebsiteFollow along on social media:YouTube: @isabelsmithnutritionInstagram: @isabelsmithnutritionPinterest: @isabelsmithnutritionWant to learn more about how Isabel Smith Nutrition can help support you on your journey to better health? Book a call with us today: Schedule Here---------------------------RESOURCES & REFERENCES: American Society for Biochemistry and Molecular Biology
Cory grew up in Maine and after spending time as a sea kayak guide and a ski instructor, found his way to biology and laboratory research. Currently a Postdoctoral Researcher in the Haller Lab at MDI Biological Laboratory, Cory is interested in the cell biology of kidney vascularization and uses renal organoids and zebrafish to investigate how we may, one day, be able to rebuild the kidney and develop non-donor solutions to kidney transplantation.Cory was one of the 5 Minute Genius™ speakers at this past year's Maine Science Festival; you can see his talk on our YouTube channel.This conversation was recorded in May 2025. ~~~~~The Maine Science Podcast is a production of the Maine Discovery Museum. It is recorded at Discovery Studios, at the Maine Discovery Museum, in Bangor, ME. The Maine Science Podcast is hosted and executive produced by Kate Dickerson; edited and produced by Scott Loiselle. The Discover Maine theme was composed and performed by Nick Parker. To support our work: https://www.mainediscoverymuseum.org/donate. Find us online:Maine Discovery MuseumMaine Discovery Museum on social media: Facebook Instagram LinkedIn Bluesky Maine Science Festival on social media: Facebook Instagram LinkedInMaine Science Podcast on social media: Facebook Instagram © 2025 Maine Discovery Museum
In 2018, a peer-reviewed article published in Progress in Biophysics and Molecular Biology suggested the theory that octopuses could have extraterrestrial origins. As in, they're not regular Earthlings. The 33 scientists who authored the paper say, the octopus could have arrived on Earth, in some form, on board a celestial body – like an asteroid. Most of the scientific community disagreed. Experts said octopuses are alien-like, but there are clues to suggest they experienced a normal, Earth-bound evolution. However…they might hold clues about what alien behavior would look like. Today, we're joined by researcher Dominic Sivitilli, who tells us what studying octopus cognition can teach us about alien intelligence. Keep up with us on Instagram @theconspiracypod! Learn more about your ad choices. Visit podcastchoices.com/adchoices
Looking for more information on this topic? Check out the Emergent Hypertension brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts. It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks. After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.
Your cells are starving. Not for food—but for oxygen. In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Jason Sonners, world-renowned hyperbaric expert and regenerative medicine pioneer, to reveal how controlled oxygen under pressure is becoming one of the most powerful tools in anti-aging and performance science. You'll learn how hyperbaric oxygen therapy (HBOT) triggers stem cell activation, rewires your epigenome, boosts mitochondrial energy, and reverses biological aging—if you use it the right way. Jason shares breakthrough findings from his latest PhD research comparing low- and high-pressure chambers, with surprising results on inflammation, telomeres, cognitive performance, and recovery speed. This is next-gen longevity—measurable, stackable, and customizable. From sleep upgrades and HRV boosts to stacking HBOT with fasting, methylene blue, or red light, this episode dives into what it takes to oxygenate your biology at the deepest level. You'll Learn: • How hyperbaric oxygen therapy (HBOT) triggers stem cell regeneration and cellular repair • Why mild-pressure chambers may be more powerful than you think• What HBOT does to inflammation, brain fog, and biological aging markers • How to stack HBOT with fasting, red light, and methylene blue for amplified results • What Dr. Sonners' PhD research reveals about oxygen pressure and genetic expression • The truth about oxygen toxicity—and how to avoid the common mistakes • How elite performers use HBOT for brain optimization, recovery, and resilience ** Get 30% of yourr tickets to the Biohacking conference by going to https://biohackingconference.com/2025 and use code ‘OXYHEALTH' ** Thank you to our sponsors! -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Jason's Website – www.hbotusa.com • OxyHealth Website: https://www.oxyhealth.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:59 Intro • 03:14 New research on aging and oxygen • 05:39 Mild vs. hard-shell chambers • 13:05 HBOT for longevity and stem cells • 16:43 How to optimize your sessions • 22:35 Best therapies to stack with HBOT • 25:40 Oxygen delivery and safety • 26:43 Altitude and chamber effects • 30:01 Key benefits of hyperbaric therapy • 34:22 Supplement synergy and timing • 37:25 Pressure and oxygenation findings • 39:27 Medical vs. welding oxygen • 44:57 Safety myths and toxicity risks • 47:39 Future of biohacking with oxygen See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.