Podcasts about Molecular biology

Lisa Markowitz currently teaches Introduction to Cultural Anthropology, People and their Food, Anthropology of Latin America, Globalizing Inequalities, Food Justice, and Contemporary Issues in Anthropology, at the University of Louisville. Markowitz's research has focused on inequities in regional and global agrifood systems and popular efforts to transform them. These linked themes have informed her writing and scholarly-civic engagement in Andean South America and the upper U.S. South. She has carried out ethnographic field research in Peru and Bolivia, exploring the situation of peasant farmers and ranchers and their use of communal or collective strategies to improve their production systems and economic bargaining power. This experience led to a long-term interest in Andean food and agriculture as well as an engagement with building equitable food systems in the United States Her work has also addressed the roles of Non-governmental organizations as change agents in South America and the United States. Her most recent project concerns the grocery industry. Michael Perlin: Dr. Michael Perlin teaches Biology 330 Genetics & Molecular Biology, Biol 410 Misuse of Biology in Film and Pop Culture, Biol 542/642 Gene Structure and Function, Biol 416 Biotechnology Methods, and Biol 575/675 Evolution of Genes and Genomes. As a biologist Dr. Michael Perlin investigates the evolution of host/pathogen interactions, primarily at the molecular genetics and biochemical levels. The research in Michael Perlin's lab focuses on the evolution of interactions between pathogens and the hosts on which they cause disease. At present, this work has two main areas of emphasis: fungal/plant interactions and population dynamics of bacteria resistant to antibiotics.

I'm thrilled to sit down with Dr. Lorna Rodriguez, a medical doctor with a PhD in biochemistry and a true double doc!

Cystic Fibrosis and obesity?  Until recently this has not been a topic of conversation for the CF community. The reason for obesity in the CF community is better health and longer lives, so the concern is now a reality.  University of Michigan CF doctor, Carey Lumeng is researching the issue.  As he says in this podcast, researchers have a lot to learn about the connection between better health in CF and obesity.  We also talk about The Bonnell Foundation fellowship program. A few years ago we started the program to encourage doctors to work in the specialty field of cystic fibrosis. Dr. Lumeng is one of the doctors who oversees this program.Dr. Lumeng is the Frederick G.L. Huetwell Professor for the Cure and Prevention of Birth Defects and Professor in Pediatrics and Molecular and Integrative Physiology. Dr. Lumeng is the Division Chief of Pediatric Pulmonology at the C.S. Mott Children's Hospital and Associate Director of the Michigan MSTP Program.He grew up in Indiana and graduated from Princeton University in Molecular Biology. He received his PhD in Human Genetics and MD from the University of Michigan and completed residency training in Pediatrics in the Boston Combined Pediatrics Residency Program at Boston Children's Hospital and Boston Medical Center. He then completed fellowship training in Pediatric Pulmonology at the University of Michigan and started as faculty in 2006.  He runs a research lab focused on the health effects of obesity and the links between metabolism and lung health. The laboratory participates in both basic science and translational research projects in adult and pediatric obesity. He is funded by the NIH and the CF Foundation for new projects studying the changing causes of diabetes in people with CF.To contact the CF pediatric department (the Bonnell girls are pictured on this page): https://www.mottchildren.org/conditions-treatments/cystic-fibrosis-pediatric?pk_vid=6ff46bd2d38fe04c1739891353f5b28b Please like, subscribe, and comment on our podcasts!Please consider making a donation: https://thebonnellfoundation.org/donate/The Bonnell Foundation website:https://thebonnellfoundation.orgEmail us at: thebonnellfoundation@gmail.com Watch our podcasts on YouTube: https://www.youtube.com/@laurabonnell1136/featuredThanks to our sponsors:Vertex: https://www.vrtx.comViatris: https://www.viatris.com/en

Your cells are starving. Not for food—but for oxygen. In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Jason Sonners, world-renowned hyperbaric expert and regenerative medicine pioneer, to reveal how controlled oxygen under pressure is becoming one of the most powerful tools in anti-aging and performance science. You'll learn how hyperbaric oxygen therapy (HBOT) triggers stem cell activation, rewires your epigenome, boosts mitochondrial energy, and reverses biological aging—if you use it the right way. Jason shares breakthrough findings from his latest PhD research comparing low- and high-pressure chambers, with surprising results on inflammation, telomeres, cognitive performance, and recovery speed. This is next-gen longevity—measurable, stackable, and customizable. From sleep upgrades and HRV boosts to stacking HBOT with fasting, methylene blue, or red light, this episode dives into what it takes to oxygenate your biology at the deepest level. You'll Learn: • How hyperbaric oxygen therapy (HBOT) triggers stem cell regeneration and cellular repair • Why mild-pressure chambers may be more powerful than you think• What HBOT does to inflammation, brain fog, and biological aging markers • How to stack HBOT with fasting, red light, and methylene blue for amplified results • What Dr. Sonners' PhD research reveals about oxygen pressure and genetic expression • The truth about oxygen toxicity—and how to avoid the common mistakes • How elite performers use HBOT for brain optimization, recovery, and resilience ** Get 30% of yourr tickets to the Biohacking conference by going to https://biohackingconference.com/2025 and use code ‘OXYHEALTH' ** Thank you to our sponsors! -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Jason's Website – www.hbotusa.com • OxyHealth Website: https://www.oxyhealth.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:59 Intro • 03:14 New research on aging and oxygen • 05:39 Mild vs. hard-shell chambers • 13:05 HBOT for longevity and stem cells • 16:43 How to optimize your sessions • 22:35 Best therapies to stack with HBOT • 25:40 Oxygen delivery and safety • 26:43 Altitude and chamber effects • 30:01 Key benefits of hyperbaric therapy • 34:22 Supplement synergy and timing • 37:25 Pressure and oxygenation findings • 39:27 Medical vs. welding oxygen • 44:57 Safety myths and toxicity risks • 47:39 Future of biohacking with oxygen See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep. 182 (Part 2 of 2) | Robert Lawrence Kuhn, producer of the popular PBS series Closer to Truth, which explores consciousness, the mystery of existence, and related topics with an open-minded approach, recently authored a remarkable article: “A Landscape of Consciousness,” in which he surveyed over 200 theories about what consciousness is. Robert tells how he inhabited each theory for a few days while writing it up, and discovered that unlike with other fields of knowledge, a study of consciousness produces more theories the more we know, rather than narrowing the field down. He emphasizes we need to be expansive with our universe of understanding of what consciousness is, and realize that how we engage with the Big Questions of life depends upon our particular theory of consciousness.Robert tells how the Big Questions, notably what is consciousness and why is there something rather than nothing, have called him all his life, leading him to create the Closer to Truth series, to explore these questions with the leading minds of our time. What Robert didn't know to begin with, but marvels about now, is how the passion for delving into the most fundamental, existential questions we face as humans unifies people around the world, from every demographic, providing a unique and wonderful point of integration. This is a fascinating, warm, engaging conversation that draws us ever farther into an exploration of the mysteries of life, where we glimpse what lies at the core of humanity. Recorded April 17th, 2025.“It's not that we have too many theories of consciousness, it's that we have one too few.”Topics & Time Stamps – Part 2The challenge of putting these theories into a digestible form (00:54)Understanding our personal theories of consciousness as extensions of our worldview (03:14)Our own theories often evolve from materialism to panpsychism to idealism (07:11)How the title Closer to Truth for the PBS/YouTube series came about (11:59)It's easier to entertain materialist or atheist theories in environments constructed by humans—exposed to the natural universe, you encounter awe, wonder, connection (14:04)The concept of awe and transcendence in art and how it reflects our nature of mind (16:16)What has exploring these theories of consciousness done to Robert? (17:59)The closer we look, the more we end up in bottomless mystery (23:36)How exploring the Big Questions unifies people—cutting across religion, race, culture (25:28) Acknowledging the limits of knowledge—epistemic humility—appreciating the mystery, and universality (29:54)The deeper your understanding goes, the richer your appreciation and awe (31:16)Resources & References – Part 2Robert Lawrence Kuhn, creator, producer, and host of the PBS series, Closer To TruthRobert Lawrence Kuhn, “A Landscape of Consciousness,”article in Progress in Biophysics & Molecular Biology, August 2024Paul Davies, quantum physicist, director of BEYOND: Center for Fundamental Concepts in Science, “The universe is about something.”

Thomas Lo, M.D., D.ABA, aka "Chef Dr. Lo," is a board-certified Anesthesiologist, Chef, CEO, and Entrepreneur. After graduating from Yale University with a degree in Molecular Biology, Dr. Chef Lo began his professional culinary career studying at the French Culinary Institute in New York. With a strong background in fundamental culinary techniques, Thomas interned at Veritas and Lupa Osteria and then joined the opening team of Virot restaurant at the Dylan Hotel in New York. Chef Dr. Lo is also the owner and culinary director of Spy C Cuisine restaurant in Forest Hills, New York. Spy C Cuisine has quickly gained critical accolades from the New York Times and received its first Michelin Bib Gourmand in 2020. With the understanding of the molecular physiology of taste, Chef Dr. Lo enjoys playing with the palate by synergistically combining flavor combinations and balancing the harmonies of sweet, salty, bitter, and sour. By contrasting various textures of his dishes, Chef Dr. Lo attempts to introduce the complexities and subtleties of food to you. As a Chef Physician, he is able to educate his customers, patients, and fellow colleagues on the medicinal aspects of haute cuisine. As a chef anesthesiologist, Chef Dr. Lo is known for his Sichuan Mind-Numbing Sauce, which must be properly prepared and used for dishes to provide the perfect balanced flavor profile. When given in the proper amount, harmony is achieved; but when too much is given, the flavors are overpowering. Although this would not be like a true overdose that Chef Dr. Lo sees in the operating room, the taste of the dish becomes acrimonious.

This episode teaches that innovation is born at the intersection of curiosity and persistence. Dr. Gudrun Stengel, co-founder and CEO of Alida Biosciences, reveals how her startup is transforming the landscape of RNA research through a novel technology called proximity barcoding. Dr. Stengel's story exemplifies the power of entrepreneurial spirit in driving scientific discovery, offering a glimpse into how one idea can reshape an entire field.At Alida Biosciences, Dr. Stengel and her team are pioneering new tools for detecting RNA modifications, a largely unexplored realm of epigenetics. Using their proximity barcoding platform, researchers can read multiple RNA modifications simultaneously, uncovering potential biomarkers and therapeutic targets for diseases like cancer, Alzheimer's, and diabetes. This technology bridges a critical gap in multiomics, allowing scientists to dive deeper into how epigenetic changes influence gene expression and cellular behavior.Beyond the lab, Dr. Stengel shares her experience as a first-time founder, balancing scientific rigor with startup life. From managing a team to fundraising, her journey underscores the importance of resilience, optimism, and maintaining a long-term vision. She also offers valuable advice for budding scientists, encouraging them to embrace challenges and remain persistent in the face of setbacks. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.

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Today we are joined by a remarkable guest, Dr. Trenna Sutcliffe, a board-certified developmental-behavioral pediatrician and the founder of the Sutcliffe Clinic in the San Francisco Bay Area. Her educational history is impressive. She completed her undergraduate education in Molecular Biology and Medical Genetics followed by a masters degree in Biophysics at The University of Toronto. She obtained her Medical degree at McMaster University before her pediatric residency and training finished at the Hospital for Sick Children in Toronto. And oh by the way, she then did a year of pediatric Neurology residency and a Fellowship in Developmental Pediatrics. And finally, another Masters degree in Epidemiology at Stanford University. Thus, her educational path has allowed her to see the developmental landscape through a wider lens covering many disciplines. Dr. Sutcliffe started the first Developmental Pediatrics Clinic at Stanford and played the role of trailblazer throughout her career. With over 25 years of experience, Dr. Sutcliffe specializes in supporting children with autism, ADHD, and anxiety, offering a multidisciplinary approach to diagnosis and treatment. In this episode, she'll share her insights on the rising prevalence of these conditions, the importance of personalized care, and practical strategies for parents navigating developmental challenge. Fundamentally, Dr. Sutcliffe is a going to educate us on a better way to deliver whole person care to the developmentally challenged and beautiful children of this country. Two words encapsulate her work: empowering and thoughtful. Let's dive into this conversation with Dr. Sutcliffe to learn how we can help our children thrive! Dr. M

What happens when scientific curiosity meets life-changing opportunity? Nicole Mumbi shares her remarkable journey and provides a powerful answer to this question.Moving from Nairobi, Kenya to Boston in 2019, Nicole faced the challenge of cultural transition while nurturing her budding interest in science. Though initially experiencing culture shock and language barriers, her determination never wavered. A simple middle school experiment on atmospheric pressure had already planted the seed of scientific fascination that would shape her future path.When Nicole's high school guidance counselor suggested applying to the BioBuilder Apprenticeship Program, she seized the opportunity despite her fears and busy academic schedule. At Ginkgo Bioworks' Learning Lab, Nicole and her team developed "Break the Stigma" – an innovative at-home HIV detection project that engineered bacterial cells with CD4 receptors to detect the virus in blood samples. This first-hand laboratory experience transformed her understanding of science from textbook concepts to real-world applications.The technical skills Nicole gained – from PCR to scientific presentation – became the foundation for her subsequent internship at the prestigious Ragon Institute. Now thriving as a Biochemistry and Molecular Biology student at UMass Amherst, she gives back by tutoring other students in chemistry while contemplating whether her future lies in research, medicine, or a combination of both.Throughout her story, Nicole emphasizes the importance of pushing past imposter syndrome to take chances. "I remember having this imposter syndrome person talking to me saying, 'I don't think you have enough qualifications,'" she shares. "But I was grateful for my mom's encouragement to partake in opportunities without feeling like an outsider."Learn more about BioBuilder's programs for students, educators, and industry professionals here

Michael Hughes is a postdoctoral researcher at St. Jude's Children's Hospital who studies the overlooked role of water in living systems. His work builds on a growing body of research suggesting that water is not just a passive solvent, but a highly structured, information-rich medium. Hughes proposes that under normal biological conditions, water's ability to form liquid crystalline phases, hydration shells, and coherent domains allows it to act more like an information storage system than an inert backdrop to biochemistry. Drawing on ideas like EZ water, interfacial water dynamics, and liquid-liquid phase separation inside cells that span thinkers from Gilbert Ling to Gerald Pollack, Hughes argues that health emerges from the fine-tuned electrical and structural properties of intracellular water. When this water-protein-electrical system breaks down, disease can result. He outlines a new approach to the body that's rooted in biophysics, not just molecular biology, which he believes might offer novel ways to maintain health and slow aging by restoring the electromagnetic coherence of the body.MAKE HISTORY WITH US THIS SUMMER:https://demystifysci.com/demysticon-2025PATREON https://www.patreon.com/c/demystifysciPARADIGM DRIFThttps://demystifysci.com/paradigm-drift-showPreprint of Michael's manuscript "Rethinking Cellular Organization: Phase Separation as a Unifying Principle in Molecular Biology" https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5171413Dr. Thomas Seyfried podcast w/ DemystifyScihttps://www.youtube.com/watch?v=rxHkXP3G3y4"Live Streaming of a Single Cell's Life over a Local pH Monitoring Nanowire Waveguide" https://pubs.acs.org/doi/10.1021/acs.nanolett.2c02185Rudolf Steiner's Agriculture Course: https://www.youtube.com/watch?v=fwSa8Lpy9-A 00:00 Go! 00:09:54 – Water, Fields & the Electric Body 00:15:01 – Biochemistry's Unifying Principles 00:21:26 – Water, Glutamine & Metabolism 00:23:02 – Liquid-Liquid Phase Separation 00:25:34 – Hydration & Cellular Structure 00:28:08 – Amyloids in Health & Disease 00:33:52 – Environment Shapes Amyloids 00:39:37 – Osmosis, Metabolism & Flow 00:41:04 – Soil Over Seed: Health Revolution 00:42:24 – Evolving Scientific Paradigms 00:46:08 – Cell Theory & Liquid Separation 00:50:34 – Rethinking Genetic Primacy 00:56:12 – Biochemical Research Challenges 01:01:58 – Terrain Theory & Post-Pandemic Trust 01:13:16 – Technology, Ethics & Evolution 01:16:06 – Metabolism as Societal Metaphor 01:21:09 – Lifespan, Healthspan & Food Systems 01:23:25 – Terrain Theory & Neurodegenerative Disease 01:25:10 – pH, Buffers & Biochemical Balance 01:30:03 – Cellular Function & pH Dynamics 01:35:17 – Biochemical Cell Environment 01:39:06 – Intracellular Phase Separation 01:43:07 – Insulin, Gradients & Phase Transitions 01:45:12 – Water, Food & Environmental Impacts 01:48:14 – Personal Diet & Exercise Design 01:57:09 – Experimenting with Your Health 02:00:11 – Dyno comp! #electricuniverse #biochemistry, #structuredwater , #cellularhealth, #watermemory, #metabolism, #quantumhealth, #naturalmedicine, #integrativemedicine, #nutritionalscience, #epigenetics, #philosophypodcast, #sciencepodcast, #longformpodcast ABOUS US: Anastasia completed her PhD studying bioelectricity at Columbia University. When not talking to brilliant people or making movies, she spends her time painting, reading, and guiding backcountry excursions. Shilo also did his PhD at Columbia studying the elastic properties of molecular water. When he's not in the film studio, he's exploring sound in music. They are both freelance professors at various universities. SOCIAL: - Discord: https://discord.gg/MJzKT8CQub- Facebook: https://www.facebook.com/groups/DemystifySci- Instagram: https://www.instagram.com/DemystifySci/- Twitter: https://twitter.com/DemystifySciMUSIC: -Shilo Delay: https://g.co/kgs/oty671

Sustainability in the lab isn't just a trend—it's a responsibility. In this quick but powerful Mol Bio Minutes episode, sustainability expert Sune Lund Sporring shares actionable tips to reduce energy use, manage lab waste, and transition to greener materials like Thermo Fisher's Sustain Series bio-based plastics.Discover the difference between bio-based and biodegradable, why second-generation feedstocks are a game-changer, and how to make low-impact changes without compromising performance. Learn how small shifts—like using aluminum beads instead of water in a bath or switching to carbon-reduced plastics—can significantly cut your lab's carbon footprint. And remember: if greener options aren't available, your demand can help shape the market.Helpful resource links mentioned in this episode:My Green Lab – Facts and resources about lab sustainabilityEnergy use of fume hoods – Energy use and savings ideas for fume hoodsGreener by Design – Thermo Fisher's approach to green solutionsLab Armor™ Beads – A sustainable option to replace water in water bathsInstrument trade up program – trade in your equipment to be green and give it a second lifeLab plastic waste – Stats about plastic waste in labsDoing something about it – Thermo Fisher's lower carbon plastics solutionSustain Series PCR plastics – Lower carbon footprint, without workflow interruptionReasons to believe – Fact sheet about Sustain Series PCR plastics Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.

 Scientists are using the secrets of biology to unlock living well past current human life spans. Venki Ramakrishnan shared the 2009 Nobel Prize in Chemistry for uncovering the structure of the ribosome. A member of the National Academy of Sciences, Venki runs a research group at the MRC Laboratory of Molecular Biology in Cambridge, England. He joins host Krys Boyd to discuss the quest to live forever, if that's even ethical, and what it looks like to alter our physiology. His book is “Why We Die: The New Science of Aging and the Quest for Immortality.”  Learn about your ad choices: dovetail.prx.org/ad-choices

Join us for an insightful conversation with Dr. Nadav Ahituv, a leader in human genetics and gene regulation at UCSF. He shares his personal journey from scoliosis patient to genetic researcher, exploring the mysteries of non-coding DNA, massively parallel reporter assays, and CRISPR-based therapeutic innovations.We dive into his lab's diverse projects, from decoding bat wing development and diet adaptation to tackling complex diseases like scoliosis and cancer through gene modulation. Learn how cloning is used alongside technologies like AI, genome-wide sequencing, and CRISPR to revolutionize our understanding of regulatory elements and shape the future of precision medicine.Plus, discover how a surprising approach—using modified fat cells—could be a game-changer in cancer therapy. This episode is a must-listen for anyone fascinated by the intersection of genetics, technology, and evolution. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.

Dr. Hoffman continues his conversation with Dr. Garth Nicolson, Founder, President, Chief Scientific Officer, and Emeritus Research Professor of Molecular Pathology at the Institute for Molecular Medicine in Huntington Beach, California, and Research Advisor for Nutritional Therapeutics, makers of NTFactor.

Unlocking the Power of Mitochondria: Dr. Garth Nicolson, a leading expert in molecular pathology, explores the critical role of mitochondria in energy production and overall health. His groundbreaking research reveals how repairing and restoring cell membranes improves health by increasing energy, decreasing fatigue, and slowing the aging process. The discussion delves into Dr. Nicolson's findings, including his influential fluid mosaic model of cell membrane structure. The focus then shifts to the importance of maintaining mitochondrial membrane integrity to combat aging and various age-related clinical conditions. Dr. Nicolson explains the benefits of membrane lipid replacement therapy using NT Factor Lipids to restore mitochondrial function, address fatigue, support recovery from chemotherapy, aid in chronic illnesses like fibromyalgia and long COVID, and assist in conditions such as schizophrenia, autism, and EMF sensitivity. The episode highlights the broad therapeutic potential of NT Factor Lipids, emphasizing their role in enhancing energy levels, promoting healing, and improving overall cellular health.

Dr. Jessica Rose is an artist, musician, mathematician, professional surfer, biologist, science researcher & data analysis. Dr. Rose has a Post Doc in Biochemistry at Technion Institute of Technology, Post Doc in Molecular Biology at Hebrew University of Jerusalem, PhD in Computational Biology at Bar-Ilan University, Master's in Medicine (Immunology) at Memorial University of Newfoundland, and BSc in Applied Mathematics at Memorial University of Newfoundland.DR. JESSICA ROSE:Twitter: https://twitter.com/JesslovesMJKSubStack: https://jessicar.substack.com/YouTube: https://www.youtube.com/channel/UC0EhWf2Vswdg7DwKKKZ34ngTHE RIPPLE EFFECT PODCAST:WEBSITE: http://TheRippleEffectPodcast.comWebsite Host & Video Distributor: https://ContentSafe.co/SUPPORT:PATREON: https://www.patreon.com/TheRippleEffectPodcastPayPal: https://www.PayPal.com/paypalme/RvTheory6VENMO: https://venmo.com/code?user_id=3625073915201071418&created=1663262894MERCH Store: http://www.TheRippleEffectPodcastMerch.comMUSIC: https://music.apple.com/us/album/the-ripple-effect-ep/1057436436SPONSORS:OPUS A.I. Clip Creator: https://www.opus.pro/?via=RickyVarandasUniversity of Reason-Autonomy: https://www.universityofreason.com/a/2147825829/ouiRXFoL WATCH:RUMBLE: https://rumble.com/c/therippleeffectpodcastBANNED.VIDEO: https://banned.video/channel/the-ripple-effect-podcastOFFICIAL YOUTUBE: https://www.youtube.com/@TheRippleEffectPodcastOFFICIALYOUTUBE CLIPS CHANNEL: https://www.youtube.com/@RickyVarandasTikTok: https://www.tiktok.com/@ricky.varandasLISTEN:SPOTIFY: https://open.spotify.com/show/4lpFhHI6CqdZKW0QDyOicJiTUNES: http://apple.co/1xjWmlFPodOmatic: https://www.podomatic.com/podcasts/rvtheory6CONNECT:TeleGram: https://t.me/TREpodcastX: https://x.com/RvTheory6IG: https://www.instagram.com/rvtheory6/ FB: https://www.facebook.com/TheRippleEffectPodcast/THE UNION OF THE UNWANTED: https://linktr.ee/TheUnionOfTheUnwanted

Today we discuss: Cerebrospinal Fluid (CSF) leaksAgenda:  1. Dr. Cardenas: Tell us your story!  2.     So, what is a CSF leak? a.     What is leaking? From where? Why do leaks happen? b.     Common symptoms? Uncommon symptoms? c.     Why don't more people know about this?  3.     Okay, so let's go back to basic anatomy & let's go from general to specific- talk to us about: a.     connective tissueb.     vasculaturec.     central nervous system flow: CSF, lymph, bloodd.     Relationship with bones like CCI, Eagle's, others?e.     Relationship with the vasculature/ flow in the rest of the body like pelvic venous congestion 4.     How do we evaluate for this?b.     Imagingc.     Blood patches d.     Embolization  5.     How do we TREAT this? a.     Immediate: Blood patches/ embolization/ pressure adjustments (meds, etc) b.     Counter facial strain. What is it & how does it help? Role for other physical tx like PT/ chiro?Bio: Dr Brianna Cardenas is a Physician Assistant, a certified athletic trainer and the founder of Healed and Empowered, an organization that specializes in optimizing health among those living with chronic illness. She has recently joined the team at NeuroVeda Health where she brings 13 years of healthcare experience. She is also a patient living with Ehlers-Danlos Syndrome, an “invisible” condition that can be hard to diagnose and often discounted by healthcare providers as a result. Brianna's lived experience as a patient informs her work as a healthcare provider to others.Bio: Dr. Maxwell is a Board Certified Pediatric Cardiologist and Pediatrician. He received his medical degree from Johns Hopkins Medical School and a Residency in Pediatrics at The University of California at San Francisco followed by clinical and research fellowships in Pediatric Cardiology at Lucile Salter Packard and Stanford Hospitals and Children's Hospital of Philadelphia. His research interests include study of endothelial control of vasomotor tone, nitric oxide, sports cardiology, dysautonomia, hypermobility syndromes, & mast cell activation syndrome and their relationships to environmental toxins. For his research he received an American Heart Association Award for Research in Molecular Biology and was an American College of Cardiology Young Investigator Award finalist. He has published many articles and book chapters on these subjects. For his clinical work, he has been voted by his peers as a Top Doctor in Northern California annually since 2017.Resources/ Links/ Articles: ·       https://www.eds.clinic/articles/spiky-leaky-syndrome·       https://www.medicalandresearch.com/current_issue/1962

Episode 128 In part 22 of our Sinai and Synapses interview series, we are talking with Dr Ciara Reyes-Ton. She is a biologist, science writer, and editor who is passionate about science communication to faith communities. She has a Ph.D. in Cell & Molecular Biology from the University of Michigan. She has served as Managing Editor for the American Scientific Affiliation's God & Nature Magazine. She is currently the Digital Content Editor for BioLogos and an Adjunct Professor at Lipscomb University. She also recently helped found the Science Communicators of Faith (SCF), a group dedicated to providing a supportive, collaborative, and Christ-centered community for people of all backgrounds and skill levels to grow in the craft of science communication. She is also the author of “Look Closely,” a science and faith devotional that explores the life of Christ by bringing scripture in conversation with science, from water-walking lizards to dividing cells and resurrecting corals. Outside science, she has a heart for worship and is a proud mom. https://www.mountcarmell.com/   Sinai and Synapses - https://sinaiandsynapses.org/   Support this podcast on Patreon at https://www.patreon.com/DowntheWormholepodcast   More information at https://www.downthewormhole.com/   produced by Zack Jackson music by Zack Jackson and Barton Willis 

What is autism? Is it truly on the rise, along with the broader concept of ‘neurodivergence'? With one in six children now identified as having special educational needs, could this increase be due to over-diagnosis, genetic factors, or something more? In this episode, I'm joined by three pioneers in the field—experts with extensive experience working with thousands of children diagnosed with autism. Together, we uncover the true scale of the issue and explore why our children's mental and physical health is under attack. Joining me are: Dr. Lorene Amet – Director of The Lauriston Centre in the UK, holding a PhD in Molecular Biology from the University of Oxford and a Master's in Autism Education. She has conducted postdoctoral research at Princeton and Edinburgh universities. Beth Lambert – Founder of Documenting Hope, a non-profit dedicated to children's health. She's a teacher and the author of A Compromised Generation: The Epidemic of Chronic Illness in America's Children, as well as co-author of Brain Under Attack. Dr. Heather Tallman Ruhm – A board-certified physician with a Master's degree in Public Health Policy. She has over a decade of experience as a college professor and serves as a medical advisor for Documenting Hope. Together, we dive deep into what's beneath the surface - examining why our children's well-being is increasingly under threat. Further Information Read more in my book Upgrade Your Brain and on my website www.patrickholford.com Book for charity Food for the Brain's online practitioner conference 'Our Children's Brains are in Crisis' on Thursday 24 April, 9.00am - 5.45pm (for health practitioners).  Book webinar Optimising Neurodivergence, Thursday 24 April, 6.30pm (open to all).    

Being a scientist is a way of looking at the world, and asking the question 'why' without your own pre-conceived notions. I've learned that it's also a great way of doing business. -Julia Wrin Piper How do you go from scientist to CEO? Meet Julia Wrin Piper. She's got degrees in Molecular Biology, Neuroscience, and Evolutionary Biology from UC/Berkeley, the Salk Institute for Biological Sciences, and Harvard University, and she's using years of scientific training to forward the mission of Clover, a Boston-area fast casual chain specializing in local, seasonal sandwiches and bowls. www.cloverfoodlab.com. Clover's mission is to significantly reduce carbon emissions through the creation of delicious, sustainably-sourced, plant-based fast food. Says Julia: “We take beautiful food that people are familiar with, and reinvent it with 100% locally sourced vegetarian ingredients. We want you to love your veggies so much, you dream about them.” Clover's Cambridge-based culinary experts work directly with farmers in the region. Born and raised in California's Bay Area, Julia's mom is a virologist who was at the forefront of HIV research and continued to offer her scientific expertise during the COVID-19 pandemic. Her father was a stay-at-home dad for many years before taking a job as an educator. Now a mother herself, Julia deeply appreciates the home she grew up in: “It was like no other. My mom was my role model, and having my father at home gave us a wonderful and very different perspective. What does the future look like for Clover under Julia's leadership? Chances are, there will be a Clover near you as the company eyes expansion beyond Massachusetts. “Being a scientist is a way of looking at the world, asking the question 'why' without your own pre-conceived notions. I've learned that it's also a great way of doing business. For 23 minutes with a woman who makes science yummy and fun, just hit that download button. #scientist #veggies #climatechange #STEM #local #carbonfootprint

What is the state of the intelligent design movement today? How is it faring in the scientific realm, the church, and in the public? How has the strategy of the ID movement shifted, and what has it learned over the past 20 years? Our guest today is Biola University Biology professor Doug Axe.Douglas Axe is the Maxwell Professor of Molecular Biology at Biola University, the founding Director of Biologic Institute, the founding Editor of BIO-Complexity, and the author of Undeniable: How Biology Confirms Our Intuition That Life Is Designed. After completing his PhD at Caltech, he held postdoctoral and research scientist positions at the University of Cambridge and the Cambridge Medical Research Council Centre. His research, which examines the functional and structural constraints on the evolution of proteins and protein systems, has been featured in many scientific journals, including the Journal of Molecular Biology, the Proceedings of the National Academy of Sciences, BIO-Complexity, and Nature, and in such books as Signature in the Cell and Darwin's Doubt by Stephen Meyer and Life's Solution by Simon Conway Morris.==========Think Biblically: Conversations on Faith and Culture is a podcast from Talbot School of Theology at Biola University, which offers degrees both online and on campus in Southern California. Find all episodes of Think Biblically at: https://www.biola.edu/think-biblically. Watch video episodes at: https://bit.ly/think-biblically-video. To submit comments, ask questions, or make suggestions on issues you'd like us to cover or guests you'd like us to have on the podcast, email us at thinkbiblically@biola.edu.

Are Vaccines Good For Us? Marschall S. Runge, M.D., Ph.D., was born in Austin, Texas, and graduated from Vanderbilt University with a BA in General Biology and a PhD in Molecular Biology. He received his medical degree from the Johns Hopkins School of Medicine and trained in internal medicine at Johns Hopkins Hospital. He was a cardiology fellow and junior faculty member at Massachusetts General Hospital. Dr. Runge's next position was at Emory University, where he directed the Cardiology Fellowship Training Program. He then moved to the University of Texas Medical Branch in Galveston, where he was Chief of Cardiology and Director of the Sealy Center for Molecular Cardiology. He joined the University of North Carolina (UNC) from 2000 – 2014, where he served as Charles Addison and Elizabeth Ann Sanders Distinguished Professor of Medicine, Chair of the Department of Medicine, President of UNC Physicians and Vice Dean for Clinical Affairs. Dr. Runge visits with Mark Alyn.Become a supporter of this podcast: https://www.spreaker.com/podcast/late-night-health-radio--2804369/support.

Are Vaccines Good For Us? Marschall S. Runge, M.D., Ph.D., was born in Austin, Texas, and graduated from Vanderbilt University with a BA in General Biology and a PhD in Molecular Biology. He received his medical degree from the Johns Hopkins School of Medicine and trained in internal medicine at Johns Hopkins Hospital. He was a cardiology fellow and junior faculty member at Massachusetts General Hospital. Dr. Runge's next position was at Emory University, where he directed the Cardiology Fellowship Training Program. He then moved to the University of Texas Medical Branch in Galveston, where he was Chief of Cardiology and Director of the Sealy Center for Molecular Cardiology. He joined the University of North Carolina (UNC) from 2000 – 2014, where he served as Charles Addison and Elizabeth Ann Sanders Distinguished Professor of Medicine, Chair of the Department of Medicine, President of UNC Physicians and Vice Dean for Clinical Affairs. Dr. Runge visits with Mark Alyn.Become a supporter of this podcast: https://www.spreaker.com/podcast/late-night-health-radio--2804369/support.

With Congress approving a plan to slash $880 billion from the federal budget, all eyes are turning to Medicaid as the most likely source of cuts. I asked Former North Carolina Health Secretary Kody Kinsley, KFF's Larry Levitt and California Health Care Foundation's Katie Heidorn to join me to discuss the likely shape and impact of proposed cuts, and take questions from UC Berkeley students. Kody called it a “self-licking ice cream cone”—cuts that destabilize the government, leading to further cuts. Larry warned of formula battles that will soon erupt. Katie laid out the devastating effects on state budgets.We've also released this episode as a full video episode on YouTube. Subscribe to The Other 80 YouTube channel for video extras, video episodes and viral healthcare policy content. Click here to watch this episode in full. Watch the full VIDEO version of this episode: https://www.youtube.com/watch?v=X110GShMTtE&t=52sRelevant LinksKFF: The Public's View on Potential Changes to MedicaidKFF: Impact of Medicaid Per Capita Cap Kody Kinsley testimony to Congress on MedicaidPre-election episode with Larry LevittKFF: Can Republicans cut $880 Billion without Slashing Medicaid?CBPP: Impact of Medicaid CutsCHCF: Defending Medi-Cal in 2025About Our GuestsKatie Heidorn is the director of state health policy at CHCF, where she leverages the foundation's data, expertise, and partnerships to help California's state government make informed decisions about health care. Katie is based in CHCF's Sacramento office.Katie has nearly two decades of experience working in health policy, government, and nonprofits and is a skilled leader, facilitator, and communicator. She comes to CHCF after more than two years as executive director for the Insure the Uninsured Project (ITUP). Before that, Katie was the government affairs advocate for Health Net and the development director and policy lead at the nonprofit California Coverage and Health Initiatives. Katie spent a decade in California state government, including as a deputy secretary for the California Health and Human Services Agency and principal consultant in the Senate Appropriations Committee. She is also an alumna of the California Senate Fellows Program.Katie received her master's degree in Public Administration from the University of Southern California and bachelor's degree in Biochemistry and Molecular Biology and Comparative Literature from the University of California, Davis.Source: https://www.chcf.org/person/katie-heidorn/Kody...

With prior Mol Bio Minutes episodes covering DNA form migration and staining considerations for nucleic acid gel electrophoresis, we tie it all together with this great set of overall tips, tricks and resources for the topic. Anyone that's ever run a gel has undoubtedly produced gels with smeared, faint or poorly separated bands. What causes these and how can you avoid them?  Well, Aistė Polikaitytė, Scientist at Thermo Fisher Scientific is here to cover the likely causes and troubleshooting tips to help avoid the most common gel issues. She touches on how much sample to load, the importance of reagent selection, gel preparation, separation conditions, staining, as well as purification and contamination considerations. Helpful resource links mentioned in this episode:Selection guide for electrophoresis dyes and buffersLearn how using precast E-Gel agarose gel can help avoid common issuesA helpful troubleshooting guide for nucleic acid gel electrophoresisView an on-demand webinar covering these topics in more detail Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.

Dr. Eric Kmiec is Director of the Gene Editing Institute of the Helen F. Graham Cancer and Research Institute at Christiana Care Health System. He also holds faculty appointments at the University of Delaware and the Wistar Institute. Eric and his colleagues are working to develop new ways to treat cancer by destroying the genes that cause cancer cells to be resistant to typical therapies like chemotherapy, radiation, or immunotherapy. Throughout his life, Eric has enjoyed sports. He particularly likes playing baseball and hockey, and he still plays baseball competitively in a league in Philadelphia. Eric also spends much of his time doing landscaping and yard work. He Received his B.A. in Microbiology from Rutgers University, his M.S. in Cell Biology and Biochemistry from Southern Illinois University, and his Ph.D. in Molecular Biology and Biochemistry from the University of Florida School of Medicine. He conducted postdoctoral research at the University of Rochester before joining the faculty at the University of California, Davis in 1987. Since then, he has served on the faculty of Thomas Jefferson University, the University of Delaware, and Delaware State University. In addition, Eric founded, consulted for, and served as Vice President of Kimeragen, Inc., he was Chief Scientific Advisor for the Genomics Division of Tapestry Pharmaceuticals, was an Eminent Scholar and Director of the Marshall University Institute for Interdisciplinary Research, and also served as Co-Founder, Chief Scientific Officer, and a Board Member of OrphageniX. Eric has received numerous awards and honors over the course of his career, including receipt of the 2012 Proudford Foundation Unsung Hero Award in Sickle Cell Disease, designation as an Honorary Commander of the 436th Air Wing at Dover Air Force Base in 2013 and 2014, and also induction into the Southern Illinois University, Edwardsville Alumni Hall of Fame in 2012. Further, Eric and the team at the Gene Editing Institute were recently awarded the inaugural Life Sciences and Bio Innovation Award from the Philadelphia-Israeli Chamber of Commerce. In our interview, Eric shared his experiences in life and science.

In this episode of Absolute Gene-ius, Dr. C. Dustin Rubinstein takes us inside the world of advanced genome editing, where cutting-edge tools like CRISPR and digital PCR are helping shape the future of biomedical research.As the Director of the Advanced Genome Editing Laboratory at the University of Wisconsin-Madison, Dr. Rubinstein shares how his lab develops genetically engineered pig models to study diseases like neurofibromatosis and cancer, providing researchers with more clinically relevant models than traditional small animals. He explains how digital PCR plays a crucial role in confirming genome edits with absolute precision, eliminating the ambiguity that often comes with qPCR and sequencing alone. The discussion dives into the advantages of dPCR for copy number variation analysis and gene editing confirmation, emphasizing the importance of multiple complementary technologies in modern molecular biology.Beyond the science, Dr. Rubinstein reflects on his career path, the value of mentors, and the unpredictable nature of scientific discovery. He also joins in on some lighthearted lab humor and shares his most embarrassing (and proudest) moments in research. Tune in for an insightful and entertaining look at the intersection of gene editing, career evolution, and the future of molecular biology.Visit the Absolute Gene-ius pageto learn more about the guests, the hosts, and the Applied Biosystems QuantStudio Absolute Q Digital PCR System. 

Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz  or www.curranz.co.uk to order yours This week on the podcast, Mikki speaks to Dr Paul Reynolds about the effects of vaping on health, particularly its impact on inflammation, cancer risk, and pregnancy outcomes. Dr Reynolds, whose background is in lung development and disease, has been investigating how e-cigarettes influence inflammatory pathways, glycation, and long-term health risks.In this conversation, they discuss why breathing is more than just taking in oxygen and how air quality plays a critical role in overall health. Dr Reynolds explains glycation—how it damages the body—and how inflammation, often seen as a necessary defence mechanism, can sometimes do more harm than good.Mikki and Dr Reynolds delve into the chemicals found in e-cigarettes, comparing their inflammatory effects to traditional cigarettes. They explore whether vaping genuinely helps smokers quit or if it fosters new dependencies, as well as the risks of secondhand exposure and how vaping should be approached from a public health perspective.Dr Reynolds shares findings from his research on vaping during pregnancy, including its effects on foetal and placental weight, and the potential implications for conditions like intrauterine growth restriction (IUGR) and preeclampsia. They also discuss how e-cigarette flavours—such as Red Hot and Green Apple—can influence cancer cell invasion and inflammation, raising questions about whether some flavouring compounds should be restricted.With vaping still largely unregulated in many areas, Dr Reynolds offers insights into where research should focus next, what policymakers need to consider, and whether vaping should be treated with the same caution as smoking.This is a must-listen for anyone interested in the science behind vaping and its potential long-term health consequences. Enjoy the conversation!Dr Paul Reynolds is a professor in the Department of Cell Biology and Physiology at Brigham Young University, with a research focus on lung development, pulmonary disease, and the effects of environmental exposures such as tobacco and vaping aerosols on respiratory health. He holds a PhD in Developmental and Molecular Biology from the University of Cincinnati and has conducted extensive research on pulmonary injury, oxidative stress, and inflammatory pathways. His work examines how vaping impacts lung function, foetal development, and cancer progression, with recent studies exploring the role of e-cigarette flavours and nicotine in inflammation and disease risk. Dr Reynolds has received multiple awards for his research and teaching, including the Parker B. Francis Fellowship in Pulmonary Research, and is an active member of organisations such as the American Physiological Society and the American Thoracic Society.Dr Paul https://cell.byu.edu/directory/paul-reynolds Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwilliden

Support the show and get 50% off MCT oil with free shipping -- just leave us a review on iTunes and let us know!https://podcasts.apple.com/us/podcast/live-beyond-the-norms/id1714886566 Most longevity research overlooks the powerful connection between reproductive function and lifespan. According to Zack Varkaris, maintaining fertility longer might be the secret to gaining up to 20 extra years of vibrant health—with the research showing women who experience menopause just 5 years later than average live 11 years longer.In this episode, Zack reveals how autologous stem cell treatments can rejuvenate ovarian function, potentially reversing menopausal symptoms and extending the reproductive window. He also introduces the concept of "Freudenspanne"—how our emotional states directly impact biological aging markers."If you can extend [fertility], it's much better than actually reversing infertility." ~ Zack VarkarisAbout Zack Varkaris:Zack Varkaris is the scientific director and Founder of Austin Biotec. He holds a Bachelor of Science in Marine and Molecular Biology from Heriot-Watt University. Working by the ethos that "a functional reproductive system and aesthetic maintenance is the foundation for a fully extended life," Zack is developing technologies that could extend lifespan by up to 20 years. His work focuses on stem cell therapies for ovarian rejuvenation and the connection between emotional state and biological aging.Connect with Zack Varkaris:- Website: https://www.austinbiotec.com/ - Instagram: https://www.instagram.com/austinbiotec Connect with Chris Burres:- Website: https://www.myvitalc.com/ - Website: http://www.livebeyondthenorms.com/ - Instagram: https://www.instagram.com/chrisburres/ - TikTok: https://www.tiktok.com/@myvitalc - LinkedIn: https://www.linkedin.com/in/chrisburres/ 

Glucose is the main source of energy for all forms of life, but it isn't usually stored as individual C6H12O6 molecules. Animals use glycogen to do that job. Glycogen is a large branched polymer of glucose molecules, linked together by α-1,4 and α-1,6 glycosidic bonds. The liver and muscles break down the stored glycogen whenever the body needs an extra boost of glucose. Glycogen storage diseases are genetic defects in glycogen metabolism resulting in accumulation of glycogen. What happens when macromolecules accumulate in cells? Cell damage and dysfunction. Because the liver and muscles are the two main organs that use glycogen, they are also the two most affected by glycogen storage diseases. In the liver, glycogen accumulation leads to hypoglycemia since the glycogen can't be broken down to glucose. Damage to the liver from extra glycogen can also lead to liver failure or even liver cancers. In the muscles, glycogen accumulation causes weakness, exercise intolerance, and potentially heart failure. There are at least 12 distinct glycogen storage diseases, but we'll cover only the 4 most common ones. After listening to this Audio Brick, you should be able to: Identify the most common glycogen storage diseases: von Gierke disease (type 1), Pompe disease (type 2), Cori disease (type 3), and McArdle disease (type 5). Identify the enzymes deficient in each of the most common glycogen storage diseases. Describe the clinical manifestations of each of the most common glycogen storage diseases. Describe management for each of the most common glycogen storage diseases. You can also check out the original brick from our Cellular and Molecular Biology collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks.  After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology. *** If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts.  It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks.  After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.

Dr. Niraj Rai is one of the world's foremost archaeogeneticists and molecular biologists. He is the group Head of the Ancient DNA Lab at Birbal Sahni Institute of Palaeosciences, Lucknow. He did his PhD from Centre for Cellular and Molecular Biology, Hyderabad.Dr Niraj was one of authors of consequential paper published in 2019 in one of the world's most prestigious publication (CELL). It was based on the DNA successfully extracted by Niraj and his team from a 2500 year old woman's skeletal found in Rakhigarhi, Haryana which was the largest site of Indus-Sarasvati Valley or Harappa Civilisation.

In this episode, Adam Coster, CEO of Butterscotch Shenanigans, shares his unique journey of joining and growing the indie studio with his brothers Sam and Seth. Adam discusses their beginnings in 2012, the steep challenges they faced, and how a personal family crisis redefined their mission to bring joy through games.  He then shares insights into their different projects, including the highly anticipated sequel Crashlands 2, set for release in April. Balancing roles at the studio, the evolving game industry, and the impact of subscription services, Adam offers a candid look at the realities of indie game development. He also provides useful, actionable advice for aspiring game developers and discusses the potential and limitations of incorporating AI into game dev. Join us as we explore the fascinating intersection of science, family, and grassroots game development to share joy. Bio: Adam Coster's love for science carried him through a PhD in Cellular & Molecular Biology. Turns out it wasn't science he was into, but solving hard problems in general. Building a company from scratch in the highly-competitive and rapidly-changing games industry certainly fit that bill, and so Adam joined the team immediately after defending his dissertation. Adam creates all of the web technology that powers Butterscotch Shenanigan's games and studio, crunches numbers to figure out how the industry works, leads our business development efforts, and makes sure that the team has what it needs to make great games. Show Links: * Crashlands 2 - trailer * Crashlands 2 - Steam * Global Game Jam - website * PopCon Indy - website * GameMaker game engine - website * Battle Chef Brigade Deluxe - Steam * Butterscotch Shenanigans - podcast * Scientists Warn Trump's NIH Cuts Will Drop ‘Atom Bomb' On Health Research - HuffPost * The Creator of ‘NBA Jam' Admits That The Pistons Are A Cheat - SBNation * What Is ‘Balatro' And Why Is Everyone Addicted To It? - Forbes Connect With Links: * Adam Coster - website * Adam Coster - LinkedIn * Adam Coster - Bluesky * Butterscotch Shenanigans - website * Butterscotch Shenanigans - games * Butterscotch Shenanigans - YouTube Game Dev Advice Links:  * YouTube Podcasts - check out this episode with a guarantee of 100% more video * Patreon - career coaching through the Gain Wisdom membership * Game Dev Advice hotline: (224) 484-7733 * website - show notes, links, stuff * info@gamedevadvice.com - reach out! * Subscribe and go to the website for full show notes with links Learn more about your ad choices. Visit podcastchoices.com/adchoices

Max Pearson presents a collection of the week's Witness History interviews from the BBC World Service.We hear about the moment Dr Max Perutz discovered the haemoglobin structure.Our expert is Professor Sir Alan Fersht, who is a chemist at the Medical Research Council Laboratory of Molecular Biology and knew Dr Perutz personally.We also hear about 22 Inuit children from Greenland's indigenous population who were sent to Denmark as part of a social experiment in 1951.Also, when mixed-raced children from the then Belgian Congo known as ‘métis', were forcibly taken from their homes in 1953.When an eruption of violence in Assam led to an estimated 3,000 being killed in the Nellie massacre of 1983.Finally, the devastating impact of the 2010 tsunami in Chile and a woman who survived it.This programme contains outdated language which some people might find offensive.Contributors: Lectures and programmes from the BBC archive Professor Sir Alan Fersht - chemist at the Medical Research Council Laboratory of Molecular Biology. Helen Thiesen - a child in Denmark's Inuit children social experiment. Marie-José Loshi - one of the mixed-race ‘métis' who was forcibly removed from her home in the then Belgian Congo. Bedabrata Lahkar - a journalist for the Assam Tribune newspaper at the time of the Nellie massacre. Alison Campbell - a survivor of Chile's 2010 tsunami.(Photo: Dr Max Perutz and Dr Paul Kedrew. Credit: Hulton Deutsch/Contributor via Getty Images)

We're experimenting and would love to hear from you!In this episode of 'Discover Daily', a massive leak from the Black Basta ransomware group reveals shocking details about modern cybercrime networks, including a 17-year-old member and $28.7M ransom demands. Security researchers uncover how the group uses corporate tools like ZoomInfo to target English-speaking organizations, while internal conflicts stall their operations. Dive into the dark world of double extortion tactics and parallels to the infamous Conti ransomware leak.In medical tech, meet Mal-ID – an AI breakthrough analyzing immune cells to detect diseases like HIV, lupus, and COVID-19 from a single blood test. Discover how machine learning decodes B-cell and T-cell receptor patterns, offering hope for faster autoimmune disease diagnosis and silent infection detection. This "one-shot sequencing" method could revolutionize personalized medicine by mapping your immune system's entire history.Lastly, evolution gets a rewrite as scientists discover gene loss drives adaptation in marine life. A Molecular Biology and Evolution study shows how sea squirts called appendicularians thrived by deleting 16 key genes, enabling radical ocean adaptations and hidden "cryptic species." Explore the "less is more" evolutionary model challenging assumptions about genetic complexity – and what it means for future bioengineering breakthroughs.From Perplexity's Discover Feed:https://www.perplexity.ai/page/leaked-chat-logs-expose-ransom-TNwzdMedSOCWv34yS7HItg https://www.perplexity.ai/page/ai-tool-diagnoses-diabetes-hiv-60yD.7CfT9OBJzcTZ.LYMw https://www.perplexity.ai/page/scientists-develop-new-view-of-LQXruZGGQ1Oxdf.UzbgaJgIntroducing Perplexity Deep Research:https://www.perplexity.ai/hub/blog/introducing-perplexity-deep-research Perplexity is the fastest and most powerful way to search the web. Perplexity crawls the web and curates the most relevant and up-to-date sources (from academic papers to Reddit threads) to create the perfect response to any question or topic you're interested in. Take the world's knowledge with you anywhere. Available on iOS and Android Join our growing Discord community for the latest updates and exclusive content. Follow us on: Instagram Threads X (Twitter) YouTube Linkedin

Kallie Fell started her professional career as a scientist in the Department of Obstetrics and Gynecology at Vanderbilt University Medical Center utilizing a Master of Science degree in Animal Sciences with an emphasis on Reproductive Physiology and Molecular Biology from Purdue University. While assisting in the investigation of endometriosis and pre-term birth, Kallie simultaneously pursued a degree in nursing with hopes of working with women as a perinatal nurse. After meeting Jennifer Lahl at a conference, Kallie became interested in the work of the Center for Bioethics and Culture (CBC) and started volunteering with the organization. Kallie is deeply passionate about women's health. She continues to work, as she has for the past six years, as a perinatal nurse and has worked with the CBC since 2018, first as a volunteer writer, then as our staff Research Associate, and now as the Executive Director. In 2021, Kallie co-directed the CBC's first documentary on “transgender medicine” titled Trans Mission: What's the Rush to Reassign Gender? In 2022 Kallie co-wrote and co-produced the CBC's latest film, The Detransition Diaries: Saving Our Sisters. Kallie also hosts the popular podcast Venus Rising and is the Program Director for the Paul Ramsey Institute. Her latest film, The Lost Boys: Searching for Manhood is set for release in January 2024 as is her new book, co-authored with Jennifer Lahl, The Detransition Diaries.

Looking for more information on this topic? Check out the Acid-Base Disorders: Putting it all Together brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts.  It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Twitter: https://twitter.com/mesage_hub Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including over 800 Rx Bricks.  After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.

Looking for more information on this topic? Check out the Adrenal Insufficiency brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts.  It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks.  After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.

Transcript with time code:  https://cuttingedgehealth.com/wp-content/uploads/2025/02/Transcript-47-Dr-Venki-Ramakrishnan.pdf   In this episode, Jane interviews Nobel Prize winner Venki Ramakrishnan, a molecular biologist who offers a balanced perspective on the anti-aging field.   Ramakrishnan discusses various promising areas of anti-aging research, including caloric restriction drugs like rapamycin, senolytics to target senescent cells, and stem cell therapies. He emphasizes the importance of clinical trials and cautions against rushing into unproven treatments. The conversation covers lifestyle factors that can promote healthy aging, such as regular exercise, proper nutrition, and maintaining social connections.   Ramakrishnan shares personal insights, including his father's experience of maintaining an active lifestyle until age 99. He also touches on his own career journey and winning the Nobel Prize. Throughout the interview, he stresses the need for a scientific approach to anti-aging research while acknowledging the urgency felt by many to combat aging. The podcast provides a thoughtful exploration of the current state of anti-aging science, balancing excitement for potential breakthroughs with the need for rigorous scientific validation.   *****   Venki Ramakrishnan shared the 2009 Nobel Prize in Chemistry for uncovering the structure of the ribosome. A National Academy of Sciences member, Venki runs his research group at the MRC Laboratory of Molecular Biology in Cambridge, England. From 2015 to 2020, he served as president of the Royal Society, one of the world's oldest scientific organizations. He is the author of the frank scientific memoir Gene Machine: The Race to Decipher the Secrets of the Ribosome and Amazon bestselling book Why We Die: The New Science of Aging and the Quest for Immortality.   *****   Cutting Edge Health podcast website: https://cuttingedgehealth.com/   Cutting Edge Health Social and YouTube:   YouTube channel: youtube.com/@cuttingedgehealthpodcast   Instagram - https://instagram.com/cuttingedgehealthpodcast   Facebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756   Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.   Special thanks to Alan and Maria on the Cutting Edge Health team!    

Guest Kristy Red-Horse is a biologist who specializes in coronary artery development and disease. She says the latest advances in treatment of blockages could do away with invasive bypass surgeries in favor of growing new arteries using molecules like CXCL12, known to promote artery regrowth in mice. Red-Horse explains how leaps forward in medical imaging, expanding atlases of gene expressions, and new drug delivery mechanisms could someday lead to trials in humans. But, before that day can arrive, much work remains, as Red-Horse tells host Russ Altman in this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your quest. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Kristy Red-HorseKristy's Lab: Red-Horse LabConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces Kristy Red-Horse, a professor of biology at Stanford University.(00:03:46) Replacing Open-Heart SurgeryWhy bypass surgery is invasive, risky, and requires long recovery.(00:05:09) Challenges in Artery GrowthThe difficulty of targeting artery growth with medical interventions.(00:07:32) The Role of Collateral ArteriesDefinition and function of collateral arteries as natural bypass.(00:09:37) Triggers for Natural Bypass FormationGenetic factors that may influence the growth of these bypass arteries.(00:10:49) Unique Properties of Coronary ArteriesChallenges of ensuring artificial growth replicates natural artery function.(00:13:04) The Discovery of CXCL12A key molecule that stimulates collateral artery formation.(00:16:16) Precise Artery Growth ControlThe results of targeted CXCL12 injections into mice hearts.(00:17:32) CXCL12's Overlooked RoleThe molecule's role in the immune system and stem cells.(00:20:27) Guinea Pigs and Heart Attack ResistanceHow guinea pigs naturally develop collaterals.(00:23:19) Preventing Heart DiseaseUsing artery growth treatments to target early-stage coronary disease.(00:25:25) Breakthroughs in Imaging TechnologyNew technology that enables identification of collateral growth pathways.(00:27:07) How Collateral Arteries FormThe two mechanisms in which new arteries form.(00:28:48) The Future of Medical Artery GrowthThe possibility of eliminating bypass surgery with targeted artery growth. Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

In this final episode of our three-part series, we welcome back Dr. Bill Andrews, world-renowned telomere scientist and founder of Sierra Sciences. If you've been captivated by the journey through telomere science so far, you won't want to miss this deep dive into the future of telomerase research and its groundbreaking potential to reverse ageing at the genetic level. In this episode, Dr. Andrews reflects on the progress made in telomere science and shares his latest insights on how telomerase activation could become a mainstream therapy for longevity and disease prevention. He also unpacks the challenges, opportunities, and what lies ahead in the quest for cellular rejuvenation. Key Discussion Points:  Telomerase Activation – Practical Applications & Next Steps What widespread telomerase activation could mean for ageing and chronic disease prevention. How telomerase therapies might revolutionise healthcare in the next decade.  New Discoveries in Telomere Research The most recent advancements and promising compounds for telomerase activation. Understanding the role of telomeres in age-related diseases and how targeting them may prevent or reverse these conditions.  Balancing Safety & Innovation Regulatory and safety considerations for bringing telomerase activators to market. How to stay informed and support the development of telomerase-based therapies.  Longevity Science & Society – What's Next? The ethical and societal implications of dramatically extending human lifespan. Addressing skepticism and dispelling myths around telomerase research. What You'll Learn in This Episode: ✅ The difference between theoretical longevity interventions and those closest to clinical application. ✅ How telomerase research aligns with other emerging fields of longevity science. ✅ Why understanding telomeres is key to unlocking better healthspan and longer life. ✅ The real-world implications of reversing cellular aging and how you can be part of the movement. About Dr. Bill Andrews: Dr. Andrews is a molecular biologist, biotech pioneer, and ultramarathon runner who has dedicated over 30 years to the study of telomeres and telomerase. He holds more than 50 U.S. patents related to telomerase activation and continues to push the boundaries of what's possible in longevity science through his work at Sierra Sciences. Dr. Andrews has been featured in Popular Science, The Today Show, and documentaries like The Immortalists,  where he co-stars with Dr. Aubrey de Grey.

Part 2 of 2: Our guest today is Oguzhan Atay, Co-founder & CEO of BillionToOne. BillionToOne is a precision diagnostics company that quantifies biology to create powerful molecular diagnostics. They work to improve disease detection by counting molecules with their proprietary molecular counting platform. They place patients at the forefront of everything they do and are currently applying their proprietary technology to non-invasive prenatal screening and liquid biopsy. Oguzhan holds a Ph.D. from Stanford in Systems Biology, where he implemented machine learning algorithms and mathematical models to solve specific problems in cellular biology and developed a data-driven mathematical framework to simplify the analysis of complex biological networks. He also has a degree in Molecular Biology from Princeton, as well as minors in Computer Science, Physics, and Applied Mathematics. Oguzhan not only combines deep technical expertise with visionary leadership, but he also has an incredibly inspirational immigrant journey, which makes this series a must-listen for first-time founders, scientists, and industry leaders alike.

Have an idea or tip? Send us a text!Ever wondered how a CEO transitions from a world of molecular biology and tech startups to heading a thriving photography business? Join us as we uncover Jasmeet Singh's incredible journey from science to the shutter, where his teenage passion for photography evolved into a successful career as the CEO and chief photographer of 415 Headshots. You'll hear firsthand how a stopover at a tire shop unexpectedly equipped him with core skills for his future venture. Singh's story is a testament to the power of passion and adaptation. He shares his strategic insights into client acquisition through savvy SEO tactics and the art of creating a warm, welcoming environment that makes each photo session a breeze. His journey is a captivating blend of calculated risk and relentless pursuit of learning.Take a closer look at San Francisco's bustling corporate headshot scene and discover how Singh strategically positioned his business to cater to the city's dynamic workforce. Offering quick and affordable 15-minute sessions, he strikes the perfect balance between high-end and budget photography, meeting the needs of startup professionals and established firms alike. We also explore Singh's thoughtful market research-driven expansion across California, tailoring services to diverse clientele from creatives in Sacramento to corporate clients in San Francisco. Plus, learn how he's incorporating video services to meet rising demands, all while maintaining authenticity in professional headshots. If you're contemplating a career pivot or looking to refine your photography skills, this episode is packed with valuable insights and inspiration.MediaclipMediaclip strives to continuously enhance the user experience while dramatically increasing revenue.Buzzsprout - Let's get your podcast launched!Start for FREEIndependent Photo ImagersIPI is a member + trade association and a cooperative buying group in the photo + print industry.Photo Imaging CONNECTThe Photo Imaging CONNECT conference, March 16-17, 2025, at the RIO Hotel and Resort in Las Vegas, NDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showSign up for the Dead Pixels Society newsletter at http://bit.ly/DeadPixelsSignUp.Contact us at gary@thedeadpixelssociety.comVisit our LinkedIn group, Photo/Digital Imaging Network, and Facebook group, The Dead Pixels Society. Leave a review on Apple and Podchaser. Are you interested in being a guest? Click here for details.Hosted and produced by Gary PageauEdited by Olivia PageauAnnouncer: Erin Manning

Join me and Dr. Colleen Cutcliffe, my brilliant friend, scientist, and the powerhouse CEO of Pendulum, for our deepest dive yet into all things Akkermansia. This free-flowing conversation will take your understanding of this extraordinary strain to a whole new level. We'll explore Akkermansia's pivotal role in metabolic health—think cravings, weight regulation, A1C—and why we're deficient in the first place. Plus, we'll discuss its connection to stress, anxiety, and even neurodegenerative diseases. We'll also dive into the hotly debated topic of Akkermansia's impact on MS, unpacking both sides of the controversy. And, we'll touch on its promising influence on hormonal balance, from infertility to menopause. As someone who's deeply invested in science, I'm personally bullish on Akkermansia and trust Pendulum's products as part of my own foundational health stack. With groundbreaking science and fresh insights, this episode will change the way you approach your practice. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Colleen Cutcliffe, PhD, Co-Founder and CEO of Pendulum Therapeutics Colleen Cutcliffe is the Chief Executive Officer and co-founder of Pendulum. She has more than 25 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotechnology. Prior to starting Pendulum, Colleen was the senior manager of biology at Pacific Biosciences and a scientist at Elan Pharmaceuticals. Colleen completed her postdoctoral studies at Northwestern's Children's Memorial Hospital. Colleen received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and her B.A. in Biochemistry from Wellesley College. THANKS TO OUR SPONSOR Pendulum: https://tinyurl.com/hzbxh75f EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS Healthcare providers - Create a healthcare account with Pendulum to unlock wholesale pricing and get $50 off your first wholesale order with code WSKARA50 at https://tinyurl.com/hzbxh75f Not a practitioner but ready to try Pendulum probiotics for yourself? Take 20% off your first membership order with code KARA20 at checkout. https://tinyurl.com/2tjp3jb4 CONNECT WITH DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Group Program: https://tinyurl.com/4hvusavw Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

Part 1 of 2: Our guest today is Oguzhan Atay, Co-founder & CEO of BillionToOne. BillionToOne is a precision diagnostics company that quantifies biology to create powerful molecular diagnostics. They work to improve disease detection by counting molecules with their proprietary molecular counting platform. They place patients at the forefront of everything they do and are currently applying their proprietary technology to non-invasive prenatal screening and liquid biopsy. Oguzhan holds a Ph.D. from Stanford in Systems Biology, where he implemented machine learning algorithms and mathematical models to solve specific problems in cellular biology and developed a data-driven mathematical framework to simplify the analysis of complex biological networks. He also has a degree in Molecular Biology from Princeton, as well as minors in Computer Science, Physics, and Applied Mathematics.

In this episode, we delve into the complex topic of vaccine safety and DNA contamination with Dr. Jessica Rose, an independent researcher with a BSc in Applied Mathematics, an MSc in Immunology, a Ph.D. in Computational Biology, and two postdoctoral fellowships in Molecular Biology and Biochemistry.  Since the start of the COVID-19 vaccine rollout, Dr. Rose has been meticulously analyzing VAERS data on adverse reactions. Her mission? To uncover the truth behind past and present health policies through rigorous, data-driven research…  Hit play to learn about: How Dr. Rose's understanding of mathematics and science came into conflict during the COVID narrative. The purpose of pharmacovigilance databases. The many “scams” that took place throughout the pandemic.  What happened when Dr. Rose compared the 2019 influenza vaccine-related injuries with those of Coronavirus. What will it take to get to the bottom of the inaccuracies of public health data? How do incorrect reports impact the welfare of our society? Join the conversation now to see for yourself! You can follow along with Dr. Rose and her ongoing work on Substack and X. Boost Your Brainpower with 15% OFF!  Fuel your mind with BrainSupreme Supplements and unlock your full potential. Get 15% OFF your order now using this exclusive link: brainsupreme.co/discount/findinggenius Hurry—your brain deserves the best! Episode also available on Apple Podcasts: http://apple.co/30PvU9C

Be sure to tune in to this episode of the Precision Health and PGX Podcast as Dr. Becky Winslow, CEO of inGENEious RX Incorporated Pharmacogenomics Consulting, and Dr. Megan Landsverk, Scientific Director of MolDX® and Chief Science Officer of Palmetto GBA®, discuss how laboratories may overcome the challenges they face earning MolDX® coverage and reimbursement for their clinical pharmacogenomics tests. Specific to coverage determinations, the PGx veterans discuss test design, post-genotype translations, and technical assessments. Specific to reimbursement, the duo discusses evidence-based reporting and complete claim submissions. Also discussed is the importance of labs clearly defining intended use populations for tests and academic partnerships importance when labs develop and validate panels including drug-gene pairs the Clinical Pharmacogenetics Implementation Consortium and the United States Food and Drug Administration does not recognize as clinically utile for managing medications. Dr. Megan Landsverk is a Science Officer for Palmetto GBA, a Medicare Administrative Contractor (MAC) and a Science Director for the Molecular Diagnostic Services (MolDX) program developed to identify and establish coverage and reimbursement for molecular diagnostic services on behalf of Medicare. Dr. Landsverk received her PhD in Biochemistry and Molecular Biology from Baylor College of Medicine and postdoctoral training in Medical Genetics at the University of Washington. She is a board-certified Molecular Geneticist, completing her molecular genetics fellowship at Baylor College of Medicine. She has held multiple academic faculty positions and has numerous publications in the field of genetics. Prior to joining Palmetto, she served as a clinical laboratory director in academic, hospital, and commercial clinical laboratories and has experience in several genetic specialties including rare disease (pediatric and adult), cancer (somatic and inherited), and pharmacogenetics.

Doug Drysdale Chief Executive Officer An experienced Corporate Director and CEO: Doug has chaired the board of directors of a NASDAQ-listed company and, as a CEO for the past 12 years, has built and turned around three pharmaceutical companies. Doug has 30 years of experience in the healthcare sector. During this time, he has formed cohesive management teams, recruited board members, completed 15 corporate acquisitions across three continents, and raised $4 billion in public and private capital. Led the turnaround of Norwich Pharmaceuticals alongside investors and became the Founding CEO of the parent company, Alvogen Group. During his 5.5-year tenure as CEO, Alvogen grew from inception to $450 million in revenues across 35 countries. In early 2014, Doug led the recapitalization of NASDAQ-listed Pernix Therapeutics, raising $65 million. Within the first year of taking the helm as Chairman and CEO, Doug rebuilt the management team and board of directors, combined several operating locations, and grew the company's enterprise value from $80 million to around $800 million. Under Doug's leadership, Pernix raised $465 million of capital. From November 2017 to July 2020, Doug was the Director and CEO of Tedor Pharma, a family-owned contract manufacturing business. Doug's efforts to turn around the industry resulted in 60% revenue growth in 2019, leading to Tedor being recognized as one of America's fastest-growing companies and making it to the 2020 Inc 5000 list. Former Head of M&A at Actavis Group, leading 15 corporate acquisitions across three continents between 2004 and 2008, including a high-profile public hostile takeover attempt in Central Eastern Europe. Over this period, Doug raised approximately $3 billion in capital and managed lending syndicates, including 25+ banks, to fund the company's growth. Actavis was sold to Watson Pharmaceuticals in 2012 for EUR4.25 billion. Doug holds a bachelor's degree in Microbial and Molecular Biology from the University of East Anglia in the U.K. and was recognized as Ernst and Young's Entrepreneur of the Year in 2012. He is an enthusiastic traveler, having visited over 45 countries. He is also an avid reader and enjoys cooking and boating. This video was conducted on behalf of Cybin and was funded by Gold Standard Media LLC and/or affiliates. For our full disclaimer, please visit https://portal.goldstandardir.com/disclaimer/CYBN-183   https://ir.cybin.com/overview/default.aspx NYSE: CYBN I CBOE: CYBN   Addressing Mental Health Challenges Doug and Michael discussed the challenges and frustrations faced by patients and doctors in dealing with mental health issues, particularly clinical depression. With his background in building drug development companies, Doug highlighted the lack of practical tools for addressing these issues. Michael expressed his interest in innovative solutions to mental health problems, given his personal experience with clinical depression. The conversation was set to be more organic and conversational, with Doug sharing more about his company and their approach to mental health. Paradigm Shift in Drug Development Doug expressed his belief that their work has the potential to be a paradigm shift in drug development, moving from daily treatment of symptoms to more interventional therapies that can rapidly fix conditions like depression. He highlighted the promising results from their studies, with patients experiencing benefits lasting at least a year after just a couple of doses. Michael shared his personal experience with depression and burnout, emphasizing the importance of their work in addressing this widespread issue. He also asked Doug about his ability to anticipate future challenges and steps in the approval process for their work. Drug Development Challenges and Success Doug discussed the challenges and complexities of drug development, particularly in the mental health sector. He highlighted the team's experience and success in developing treatments, with 60+ INDs and 37 exits. Doug also emphasized the personal motivation of the team members, many of whom have been affected by mental health issues. He acknowledged the regulatory hurdles and administrative complexities involved in drug development but stressed the importance of these steps in creating effective treatments. Michael added that the success of the treatments could also positively impact the revenue of psychiatrists and their practices. Improving Mental Health Care Efficiency Doug discussed the potential of a new treatment to improve mental health care. He highlighted that depressed patients require a lot of attention, often visiting their physicians multiple times a year for medication adjustments and dealing with side effects. He also pointed out the shortage of psychiatrists and the long wait times for new patients. Doug suggested that their treatment, which only requires dosing once or twice, could keep patients out of the system for at least a year, freeing up resources for new patients. He also mentioned the potential for interventional psychiatry centers to see more patients if the treatment reduces the required visits. Mental Health and Metabolic Connection Michael and Doug discussed the challenges of mental health, particularly financial stress and depression. Michael shared his personal experience of overcoming depression with the help of medication and therapy and expressed his excitement about the potential of innovative work in mental health. Doug emphasized the link between metabolic health and mental health, suggesting that a poor diet can lead to reduced mental function and that mental health issues can affect an individual's metabolic health. Both agreed on the importance of addressing mental health issues to improve overall well-being and happiness. Phase 3 Program Progress and Strategy Doug discussed the progress of their phase 3 program, focusing on the challenges and complexities involved, such as drug scheduling and licensing. He expressed optimism about the potential of their treatments, citing their significant effects and the absence of dosing every day in their studies. Doug also outlined their long-term strategy, which includes leveraging their phase 3 approval in depression to treat other conditions and shift from daily chronic dosing to more interventional treatments. He emphasized the potential to break the cycle of polypharmacy and create a platform for various treatments. Michael supported their work and encouraged more people to learn about their efforts.  

Colleen Cutcliffe explores the microbiome's role during menopause, focusing on the estrobolome and gut bacteria's interaction with estrogen. She emphasizes the importance of gut health, particularly Acromantia, and discusses the negative impacts of birth control pills and antibiotics. Along with Dr. Mindy, they highlight essential microbes, dietary changes, and probiotics for wellness, and examine the long-term effects of weight loss drugs on the microbiome. Lastly, they stress measuring health through energy levels and the four pillars of well-being: nutrition, exercise, mental health, and the microbiome. To view full show notes, more information on our guests, resources mentioned in the episode, discount codes, transcripts, and more, visit https://drmindypelz.com/ep271 Colleen Cutcliffe is the Chief Executive Officer and co-founder of Pendulum. She has more than 15 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotechnology. Prior to starting Pendulum, Colleen was the senior manager of biology at Pacific Biosciences and a scientist at Elan Pharmaceuticals. Colleen completed her postdoctoral studies at Northwestern's Children's Memorial Hospital. Colleen received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and her B.A. in Biochemistry from Wellesley College. Check out our fasting membership at resetacademy.drmindypelz.com. Please note our medical disclaimer.

Dr. Jessica Rose is an artist, musician, mathematician, professional surfer, biologist, researcher, & data analysis. Dr. Rose has a Post Doc in Biochemistry at Technion Institute of Technology, Post Doc in Molecular Biology at Hebrew University of Jerusalem, PhD in Computational Biology at Bar-Ilan University, Master's in Medicine (Immunology) at Memorial University of Newfoundland, and BSc in Applied Mathematics at Memorial University of Newfoundland.DR. JESSICA ROSE:Twitter: https://twitter.com/JesslovesMJKSubStack: https://jessicar.substack.com/YouTube: https://www.youtube.com/channel/UC0EhWf2Vswdg7DwKKKZ34ngTHE RIPPLE EFFECT PODCAST:WEBSITE: http://TheRippleEffectPodcast.comWebsite Host & Video Distributor: https://ContentSafe.co/SUPPORT:PATREON: https://www.patreon.com/TheRippleEffectPodcastPayPal: https://www.PayPal.com/paypalme/RvTheory6VENMO: https://venmo.com/code?user_id=3625073915201071418&created=1663262894MERCH Store: http://www.TheRippleEffectPodcastMerch.comMUSIC: https://music.apple.com/us/album/the-ripple-effect-ep/1057436436Send BitCoin:  bc1qh0w0xyud67gvexwenh9fszzqy0np799h9qffyqSend Ethereum: 0xfeda6Da1EE8Aa06E0d63272c886277153C1ef34dWATCH:RUMBLE: https://rumble.com/c/c-745495ROKFIN: https://rokfin.com/RippleEffectODYSEE: https://odysee.com/@therippleeffectpodcast:dBITCHUTE: https://www.bitchute.com/channel/6bOtjURD1rds/BANNED.VIDEO: https://banned.video/channel/the-ripple-effect-podcast YOUTUBE: https://www.youtube.com/channel/UCVfy9MXhb5EIciYRIO9cKUwLISTEN:SPOTIFY: https://open.spotify.com/show/4lpFhHI6CqdZKW0QDyOicJiTUNES: http://apple.co/1xjWmlFPodOmatic: https://www.podomatic.com/podcasts/rvtheory6CONNECT:TeleGram: https://t.me/TREpodcastX: https://x.com/RvTheory6IG: https://www.instagram.com/rvtheory6/FB: https://www.facebook.com/TheRippleEffectPodcast/THE UNION OF THE UNWANTED: https://linktr.ee/TheUnionOfTheUnwanted