Podcasts about Molecular biology

Branch of biology which studies biological activity at the molecular level

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Best podcasts about Molecular biology

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Latest podcast episodes about Molecular biology

Dr. Brendan McCarthy
Estrone Explained: How Lifestyle & Hormones Impact Women's Health

Dr. Brendan McCarthy

Play Episode Listen Later Oct 30, 2025 32:36


In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, dives deep into estrone, one of the three key estrogens, and explains why understanding it is crucial for women's health. Learn about: The differences between estradiol, estriol, and estrone How estrone levels shift during perimenopause and menopause Why oral estrogen can dramatically increase estrone The impact of lifestyle factors like diet, body fat, stress, alcohol, and sedentary behavior on estrogen balance Practical tips to support healthy estrogen metabolism naturally Dr. McCarthy breaks down complex biochemistry in a clear, actionable way so you can take charge of your hormonal health.   Citations: 1. Bulun, Serdar E., et al. “Aromatase and Estrogen Biosynthesis in Adipose Tissue.” Endocrine Reviews, vol. 23, no. 3, 2002, pp. 305–342. 2. Labrie, Fernand, et al. “Importance of the Intracrinology of Estrogen Synthesis in Peripheral Tissues in Postmenopausal Women.” Journal of Steroid Biochemistry and Molecular Biology, vol. 118, nos. 4–5, 2010, pp. 273–279. 3. Sasano, Hironobu, and Toshihiko Harada. “Differential Expression of Aromatase and 17β-Hydroxysteroid Dehydrogenase Isoenzymes in Human Tissues.” Journal of Steroid Biochemistry and Molecular Biology, vol. 86, no. 3–5, 2003, pp. 327–333. 4. Yager, James D., and Nancy E. Davidson. “Estrogen Carcinogenesis in Breast Cancer.” New England Journal of Medicine, vol. 354, no. 3, 2006, pp. 270–282. 5. Cavalieri, Ercole L., and Eleanor G. Rogan. “Depurinating Estrogen-DNA Adducts, Mechanisms of Formation, and Prevention.” Clinical Cancer Research, vol. 16, no. 3, 2010, pp. 596–602. 6. Suba, Zsuzsanna. “Circulating Estrogens and Estrogen Metabolism in Obese Women.” Journal of Clinical Endocrinology and Metabolism, vol. 98, no. 11, 2013, pp. 4336–4344. 7. Simpson, Evan R., and Konstanze C. Pike. “Aromatase Expression in Adipose Tissue: Relationship to Obesity and Insulin Resistance.” Endocrinology, vol. 156, no. 9, 2015, pp. 3422–3435. 8. Key, Timothy J., et al. “Circulating Sex Hormones and Breast Cancer Risk Factors in Postmenopausal Women: Reanalysis of 13 Studies.” British Journal of Cancer, vol. 105, no. 5, 2011, pp. 709–722. 9. Stanczyk, Frank Z., et al. “Oral, Transdermal and Injectable Hormone Therapy: Pharmacokinetics and Effects on Estrone/Estradiol Ratios.” Menopause, vol. 24, no. 9, 2017, pp. 1080–1090. 10. Santen, Richard J., et al. “Estrogen Bioidentical Hormone Therapy: Route of Administration and Risk.” Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 7, 2020, pp. 2062–2074. 11. Zeleniuch-Jacquotte, Anne, et al. “Postmenopausal Levels of Estrone, Estradiol, and Estrone Sulfate and Breast Cancer Risk.” Cancer Epidemiology, Biomarkers & Prevention, vol. 23, no. 8, 2014, pp. 1531–1539. 12. Dall, Gabriella V., and Christine L. Clarke. “Local Estrogen Biosynthesis and Signaling in Breast Cancer Progression.” Steroids, vol. 78, no. 7, 2013, pp. 639–646. 13. Heald, Anthony H., et al. “Relationships Between Serum Estrone, Insulin Resistance, and Adiposity in Postmenopausal Women.” Clinical Endocrinology, vol. 67, no. 3, 2007, pp. 340–345. 14. Kuiper, George G. J. M., et al. “Estrogen Receptor β Selectivity of Estriol and Implications for Tissue-Specific Effects.” PNAS, vol. 94, no. 17, 1997, pp. 9105–9110. 15. Michnovicz, Joseph J., et al. “Dietary Indoles and Estrogen Metabolism: Effects of Cruciferous Vegetable Intake.” Journal of Nutrition, vol. 134, no. 12, 2004, pp. 3479S–   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.  

The Synthesis of Wellness
199. The Skin Barrier, Skin Health, and Skin Longevity with Olga Goldberger from IOKA Skin+Science

The Synthesis of Wellness

Play Episode Listen Later Oct 29, 2025 51:49


In this episode, we are joined by Olga Goldberger, founder of IOKA Skin + Science. Olga holds a Master's degree in Molecular Biology, and she strived to create a skincare system that applied science to active botanical ingredients that would penetrate the skin and support skin health on the cellular level.Topics: 1. Anatomy and Function of the Skin Barrier- Structure of the epidermis, highlighting the Stratum Corneum.- Role of corneocytes and intercellular lipids in barrier integrity. 2. Emulsifiers and Surfactants- Mechanisms of action.- Interaction with skin lipids and proteins.- Classification.- Transepidermal water loss (TEWL).- Wash-Out Effect. 3. Phospholipids in Skincare Formulation 4. Parabens- Endocrine implications. 5. Fragrance components 6. Synthetic colorants 7. Exfoliating agents- Chemical exfoliants and fruit-derived enzymes. 8. Lifestyle and Environmental Influences- External and internal contributors to oxidativestress. 9. Dermal Fibroblasts- Collagen and elastin. 10. NAD+ and precursors.11. Antioxidants including pterostilbene.12. Bakuchiol13. Topical acetyl hexapeptide-8 and copper tripeptide-1.14. IOKA Skin + Science.Explore all IOKA Skin + Science products here. Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Swisspreneur Show
EP#528 - Jurgi Camblong: Decoding the Path to NASDAQ: The SOPHiA GENETICS Story

Swisspreneur Show

Play Episode Listen Later Oct 29, 2025 65:24


Timestamps:05:45 - From Scientist to Startup CEO16:23 - Winning the Industries Trust With Data28:33 - The Hidden Cost of Scaling Too Fast47:31 - The Hard Truth About Going PublicEpisode Summary:Jurgi Camblong is the Co-Founder and CEO of SOPHiA GENETICS, a Swiss company using data-driven medicine to empower healthcare professionals worldwide. With a PhD in Molecular Biology from the Université de Genève, Jurgi transformed his deep scientific background into one of Switzerland's few NASDAQ-listed success stories. SOPHiA GENETICS harnesses AI and advanced bioinformatics to make genomic and multimodal data accessible and actionable for hospitals all around the world.In this episode, Jurgi shares how he founded SOPHiA GENETICS before AI became a buzzword, why timing and trust were everything when introducing cloud-based genomics to hospitals, and how a consumption-based business model helped the company stay customer-obsessed from day one. He also reflects on what it takes to educate a conservative industry, the importance of demonstrating value through accuracy, and why being early sometimes means having to build both the market and the product at once.On a more personal level, Jurgi opens up about the challenges of scaling culture beyond 100 people, what he learned from taking SOPHiA GENETICS public on NASDAQ, and the emotional toll of entrepreneurship at that level. He talks about near-failures, resilience through crises, and why—after everything—he might never again build a company with more than 100 employees.The cover portrait was edited by ⁠⁠⁠⁠⁠Smartportrait. ⁠⁠⁠⁠‍‍Don't forget to give us a follow on⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠,⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Linkedin⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠,⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ TikTok⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, and⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Youtube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠so you can always stay up to date with our latest initiatives. That way, there's no excuse for missing out on live shows, weekly giveaways or founders' dinners.

Speaking of Mol Bio
No lyophilizer? No problem. Dry-Ready reagents explained.

Speaking of Mol Bio

Play Episode Listen Later Oct 22, 2025 14:50


In this Mol Bio Minutes episode, Thermo Fisher Scientific's Dr. Agnė Alminaitė unveils an exciting new approach for assay developers: Dry-Ready™ reagents for RT-LAMP and RT-qPCR. These innovations eliminate the need for lyophilizers by enabling air drying of molecular assays in a standard heating oven, producing room temperature-stable assays in under two hours.Agnė walks listeners through how Dry-Ready differs from traditional Lyo-Ready™ and lyophilization methods, while delivering similar stability and performance. She explains the critical role of thermostable enzymes and specially developed excipient mixes that protect enzyme function during the drying process.The episode introduces two new kits: the Dry-Ready™ RT-LAMP Kit, ideal for flexible assay development and point-of-care settings, and the one-step Dry-Ready™ RT-qPCR Kit, a powerful tool for simplified, dual-function reactions. Both kits are customizable and empower even small labs to stabilize assays without complex equipment.Whether you're commercializing a kit or looking to simplify your workflow, this episode offers actionable insight into next-generation assay stabilization. And don't miss the special promo code below!Helpful resource links mentioned in this episode:Learn more about air-drying and lyophilization for assay stabilization.Visit the product pages for the Dry-Ready products Agnė introduced:Invitrogen Dry-Ready™ RT-qPCR KitInvitrogen Dry-Ready™ RT-LAMP KitAccess all Thermo Fisher Scientific promotional offersAccess your exclusive Speaking of Mol Bio promotional offerEnter code “CAZDUA” if in the U.S.Enter code “CZ7F19” in in Canada Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.

An Informed Life Radio
Is Acetaminophen Dangerous?

An Informed Life Radio

Play Episode Listen Later Oct 18, 2025 55:11


Been wondering what to believe about acetaminophen? It's found in many over-the-counter products, not just Tylenol. Guest Dr. Christina Parks earned a double major in Biochemistry and Molecular Biology and Chemistry Honors and a Ph.D. in Cellular and Molecular Biology. As an educator, she helps us all understand the science so we can make informed decisions.Reference Linkshttps://informedchoicewa.substack.com/https://www.vi-ta.org/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Progress, Potential, and Possibilities
Edward You - EHY Consulting LLC - fmr. Supervisory Special Agent, FBI's Weapons of Mass Destruction Directorate - Safeguarding Science, Innovation And The Bioeconomy

Progress, Potential, and Possibilities

Play Episode Listen Later Oct 18, 2025 56:19


Send us a textEdward You is recently coming off an amazing career at the U.S. Federal Bureau of Investigation (FBI) where most recently he served in roles as Supervisory Special Agent, National Counterintelligence Task Force, Counterintelligence Division, as well as a Supervisory Special Agent in the FBI's Weapons of Mass Destruction Directorate.  He was also previously simultaneously detailed as a Liaison Officer at the Department of Health and Human Services, Office of National Security, and as a National Counterintelligence Officer for Emerging and Disruptive Technologies, in the Office of the Director of National Intelligence (ODNI).Mr. You was responsible for creating programs and activities to coordinate and improve FBI and interagency activities to identify, assess, and respond to biological threats or incidents.  He supported FBI initiatives to build partnerships with the life sciences community, domestically and internationally, and lead efforts to identify and address potential security challenges in advanced biotechnology. His overall goal was to safeguard the scientific community, the life science research enterprise, and the U.S. bioeconomy.  Before being promoted to the Weapons of Mass Destruction Directorate, Mr. You served as a member of the FBI Los Angeles Field Office Joint Terrorism Task Force and the FBI Hazardous Evidence Response Team. Mr. You has also been directly involved in policy-making efforts with a focus on biosecurity.  He served as an active Working Group member of the White House National Security Council Policy Coordinating Committee on Countering Biological Threats and represented the FBI as an Ex Officio member of the National Institutes of Health National Science Advisory Board for Biosecurity.  He also served on two National Academies of Sciences, Engineering, and Medicine Committees, the Institute of Medicine's Forum on Microbial Threats and the Committee on Science, Technology, and Law's Forum on Synthetic Biology.  He is currently a Senior Fellow for the Scowcroft Institute of International Affairs at the Bush School of Government and Public Service at Texas A&M University.Prior to joining the FBI, Mr. You had extensive experience in academic research having worked for three years in autoimmune disease research at the Cedars-Sinai Medical Center and six years in human gene therapy and retrovirology at the University of Southern California, Keck School of Medicine, where he received his Master of Science (M.S.), Biochemistry and Molecular Biology.  Just prior to joining the FBI, Mr. You worked for three years in the commercial biotechnology sector conducting cancer research and assay development at AMGEN, Inc.Mr. You recently set up EHY Consulting LLC, dedicated to consulting activities focused on safeguarding science and innovation at the intersection of biotechnology, artificial intelligence, and national security.#EdwardYou #FederalBureauOfInvestigation #WeaponsOfMassDestructionDirectorate #FBI #SupervisorySpecialAgent #Biosecurity #Bioeconomy #Biohackers #DualUse #Anthrax #Ricin #FBIHazardousEvidenceResponseTeam #JointTerrorismTaskForce #AutoimmuneDisease #MolecularBiology #GeneTherapy #Angiogenesis #WMDCoordinator #Chemical #Biological #CBRN #UnitedNationsInterregionalCrimeAndJusticeResearchInstitute #UNICRI #NationalAcademies #NationalCounterintelligenceAndSecurityCenter #OfficeOfTheDirectorOfNationalIntelligence #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show

Alternative Talk- 1150AM KKNW
Informed Life Radio 10-17-25 Is Acetaminophen Dangerous?

Alternative Talk- 1150AM KKNW

Play Episode Listen Later Oct 18, 2025 55:11


Been wondering what to believe about acetaminophen? It's found in many over-the-counter products, not just Tylenol. Guest Dr. Christina Parks earned a double major in Biochemistry and Molecular Biology and Chemistry Honors and a Ph.D. in Cellular and Molecular Biology. As an educator, she helps us all understand the science so we can make informed decisions. Reference Links https://informedchoicewa.substack.com/ https://www.vi-ta.org/

The Tranquility Tribe Podcast
Ep. 389 Exploring Vaccine Ingredients with an Infectious Disease Scientist

The Tranquility Tribe Podcast

Play Episode Listen Later Oct 15, 2025 115:16 Transcription Available


In this powerful episode of The Birth Lounge Podcast, HeHe sits down with infectious disease scientist, Ellie to pull back the curtain on what's really behind vaccines, immunity, and medical ethics. After years working in big pharma, Ellie began questioning what she saw from the inside, and now she's here to help parents unpack the complex, often confusing world of vaccine science through an evidence-based, transparent lens. Together, HeHe and Ellie dive into everything from the ingredients found in common vaccines (and why they're there!) to the differences between live and attenuated viruses. They also explore the ethics of vaccine research, including the use of fetal cell lines, vaccinated vs. unvaccinated clinical trials, and how informed consent fits into modern medicine. This conversation isn't about fear, it's about facts. It's about asking better questions, understanding your options, and feeling confident in the choices you make for your family's health. Ellie brings scientific clarity, a refreshing dose of honesty, and a deep respect for parental autonomy to this nuanced conversation. If you've ever wanted a clearer understanding of vaccines and the ethics behind them, this episode is a must-listen. 03:27 Announcing the New Course: Pushing Out Your Big Ass Baby 05:34 Vaccine Exploration Series Finale 06:19 Ingredients in Vaccines: What You Need to Know 07:35 Interview with Infectious Disease Scientist Ellie 12:11 Ellie's Journey from Big Pharma to Vaccine Skepticism 40:44 Ethical and Scientific Concerns in Vaccine Development 01:02:33 Pharmaceutical Interactions and Clinical Trials 01:04:28 Autonomy and Vaccine Mandates 01:05:17 Herd Immunity and Vaccine Efficacy 01:06:38 Transparency and Trust in Healthcare 01:15:49 Ethics of Vaccine Studies 01:19:12 Challenges in Scientific Research 01:23:55 Vaccine Ingredients and Allergies 01:26:42 Live vs. Attenuated Vaccines 01:29:49 Shingles and Vaccine History 01:33:43 Scientific Communication and Public Trust 01:43:08 Final Thoughts and Resources   Guest Bio: Ellie is an infectious disease scientist with a powerful personal story and a passion for making science accessible. With a B.S. in Cellular and Molecular Biology and an M.S. in Infectious Diseases and Microbiology, Ellie has spent years on the front lines of science—from developing vaccines for potential bioweapons during her graduate research to working in assay development and infectious disease research within the pharmaceutical industry. Four years ago, she made the bold decision to step away from pharma and pursue a path that blends science, personal experience, and public education. Ellie was born with a left radial clubbed hand, congenital heart issues, and other challenges caused by a pharmaceutical product—an experience that has shaped her unique perspective on medicine. After undergoing countless surgeries, she deeply understands the life-saving value of western medicine, while also recognizing that alternatives can have a place in care. Ellie now dedicates herself to helping people understand complex scientific topics so they can make empowered, informed health decisions. She believes that her journey—both scientific and deeply personal—is no accident. Through all the challenges she has faced, she's seen the hand of Jesus guiding her path and believes God has kept her alive for a greater purpose.  INSTAGRAM: Connect with HeHe on IG  Connect with Ellie on IG    BIRTH EDUCATION: Join The Birth Lounge here for judgment-free childbirth education that prepares you for an informed birth and how to confidently navigate hospital policy to have a trauma-free labor experience!   Download The Birth Lounge App for birth & postpartum prep delivered straight to your phone!   RESOURCES MENTIONED: https://cogforlife.org/  https://www.cellosaurus.org/  You can search a variety of ways in the site, but one is 'browse by group' and click 'Vaccine production cell lines' 

Reefer MEDness
E110 - David Traylor and Golden Eagle Partners (Re-Hash)

Reefer MEDness

Play Episode Listen Later Oct 15, 2025 45:51


David Traylor has 2 undergrad degrees in Bio-Chemistry and Molecular Biology. He is a former pro lacrosse player. He got involved in BioTech in the 1990's and dealt with the difficulties of getting molecules like erythropoietin to market at scale. From there he got into investment banking. Obviously, with that background, the next step is to do cannabis deals on 6 of the 7 continents!Golden Eagle Partners was the first investment banking firm to jump into cannabis, which they did in 2013. In addition to doing international cannabis deals, David's experience has led him to be involved with financial and cannabis related conferences around the world. In fact, David is the reason our co-host Trevor was at CannMed 23 in Florida.Listen as Trevor and David discuss: What is THC+ and THC-? Where is the cannabis industry going in the next three years? Did Canada blow it on the business side of cannabis when all that money poured in post national legalization in 2018? Why is it so hard to scale a biological product like cannabinoids?David wraps up with talking about the importance of humility when dealing with cannabis. Whether that is dealing with patients, growing the plant or navigating the cannabis business world, we think a reminder to be humble is a wonderful mantra!Golden Eagle Partners- websiteDavid Traylor - LinkedInMusic by:Hearty Har -Scream and Shout - YouTubeAdditional Music:Desiree Dorion desireedorion.comMarc Clement - FacebookTranscripts, papers and so much more at: reefermed.ca

Progress, Potential, and Possibilities
Christian Maugee - PhD Candidate, University Of Florida - From Patient To Genetics Research Pioneer

Progress, Potential, and Possibilities

Play Episode Listen Later Oct 15, 2025 38:07


Send us a textChristian Maugee is a PhD Candidate at the University of Florida, in Genetics and Genomics ( http://www.vulpelab.net/graduate-and-undergrad-students.html ), where his research explores how gene expression differs in the hearts of individuals with Friedrich's Ataxia (FA), a rare, progressive neurodegenerative disease.  His work could lead to new insights into the cardiac complications that can be associated with FA and how to potential treat them better.Christian's dissertation work is focused on identifying gene modulators of the transcriptional phenotype of FA in human induced pluripotent stem cells differentiated into cardiomyocytes (hPSC-CMs). He accomplishes this through use of a novel method: Perturb-seq - a CRISPR screen coupled with single cell RNA sequencing (scRNA-seq) readout. Christian is driven by much more than academic curiosity, as he brings a unique and deeply human perspective to his work as someone living with FA. He doesn't just study the challenges faced by those with disabilities; he lives them. His work is not only informed by data and theory, but by resilience, authenticity, and a commitment to making research more inclusive and impactful.In the lab, Christian loves mentoring, and outside of the lab he loves fundraising and raising awareness for FA, mainly through FARA ( https://www.curefa.org/ ) and MDA ( https://www.mda.org/disease/friedreichs-ataxia ).Christian received a Bachelor's degree in Cell/Cellular and Molecular Biology, from the University of South Florida.Important Episode Link - The Science Guy: Back In The Lab For FAhttps://www.ataxia.org/billnye-for-fa/#ChristianMaugee #FriedreichsAtaxia #UniversityOfFlorida #Genetics #Genomics #MolecularBiology #UniversityOfSouthFlorida #Frataxin #MitochondrialDysfunction #OxidativeStress #Neurodegeneration #AmyotrophicLateralSclerosis #FrontotemporalDementia #Dystonia #HypertrophicCardiomyopathy #DilatedCardiomyopathy #Cardiomyocytes #InducedPluripotentStemCells #Epigenetic #BillNye #Mitochondria #RareDisease #Neurology #Biogen #Omaveloxolone #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show

People Behind the Science Podcast - Stories from Scientists about Science, Life, Research, and Science Careers
834: Examining the Genetics and Molecular Biology of Brain Aging in Humans and Non-Human Primates - Dr. Elaine Guevara

People Behind the Science Podcast - Stories from Scientists about Science, Life, Research, and Science Careers

Play Episode Listen Later Oct 13, 2025 56:02


Dr. Elaine Guevara is a Lecturer in Evolutionary Anthropology at Duke University. She teaches biology and conducts research on the evolution of primates using molecular approaches. One area of Elaine's research examines the evolution of brain aging and how brain aging differs between humans and our primate relatives, including certain species of lemurs. When it's time to relax, Elaine loves to read. She is particularly fond of Golden Age mysteries, similar modern mystery authors, investigative journalism, history, and social science content. In addition to reading, Elaine enjoys biking, being outdoors, exploring the mountains, observing wildlife, playing games, sipping wine, and hanging out with friends. She received her BA in biological anthropology from the University of California, Santa Cruz, and her MA in biological anthropology from Hunter College. During her master's program, Elaine also worked at the American Museum of Natural History as an Archives Assistant and subsequently a Database Assistant. She then received her PhD from Yale University. Afterwards, Elaine conducted postdoctoral research at The George Washington University. She joined the faculty at Duke in 2021, and she also served briefly as a faculty member at the University of North Carolina Wilmington. In our interview, Elaine shares more about her life and science.

Speaking of Mol Bio
Unlocking phagocytosis―a look at advanced cancer immunology

Speaking of Mol Bio

Play Episode Listen Later Oct 8, 2025 33:28


In this inspiring episode, Dr. Felipe Gálvez-Cancino, group leader at Oxford's Center for Immuno-Oncology, walks us through his team's groundbreaking research on macrophages, T cells, and immune regulation in solid tumors. Tracing his path from early cancer vaccine work to advanced antibody-dependent cellular phagocytosis (ADCP), Felipe shares how his team is working to reprogram tumor-associated macrophages to more efficiently eliminate cancer cells.He explains how regulatory CD4+ T cells suppress both T cell and macrophage responses within tumors and how removing that suppression can supercharge phagocytic function. We also hear how his lab is leveraging mouse models of hepatocellular carcinoma, clinical samples, and modern molecular biology techniques (like in vivo liver transfection and CRISPR-ready plasmid engineering) to study intratumor heterogeneity and antigen spreading.Felipe also reflects on the value of early molecular biology training—like mastering gigapreps—and emphasizes the importance of curiosity, persistence, and collaboration in scientific careers. Whether you're interested in cancer biology, immunotherapy, or just passionate about translating discoveries into new therapies, this episode offers both technical depth and motivational insight. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.

Ask Dr. Drew
Dr. Jessica Rose Finds DNA In Pfizer mRNA Vials With Fluorometry + Comedian JP Sears on UK Mandatory Digital ID – Ask Dr. Drew – Ep 539

Ask Dr. Drew

Play Episode Listen Later Oct 6, 2025 75:12


mRNA vaccines are not supposed to contain DNA. But Dr. Jessica Rose says a new study tested “32 vials of Pfizer and Moderna COVID products that included 16 unique lots… We did not only find DNA, we found it in ALL lots tested and most importantly, the DNA levels were all above pre-designated EMA thresholds of 10 ng/dose.” “We measured the amount of DNA in the vials using 2 methods… (qPCR and fluorometry),” she continues. “It was submitted as evidence on the congressional record by the honorable Senator Ron Johnson.” JP Sears is a comedian, author, and YouTuber known for his satirical take on politics, fitness, and faith. He hosts Awaken with JP on Rumble and YouTube. Follow at https://x.com/AwakenWithJP Dr. Jessica Rose is a Canadian researcher with a Bachelor's in Applied Mathematics and a Master's in Immunology from Memorial University of Newfoundland. She holds a PhD in Computational Biology from Bar Ilan University and completed postdoctoral research in Molecular Biology and Biochemistry. Find her at https://jessicasuniverse.com and follow at https://x.com/JesslovesMJK 「 SUPPORT OUR SPONSORS 」 Find out more about the brands that make this show possible and get special discounts on Dr. Drew's favorite products at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/sponsors⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠• FATTY15 – The future of essential fatty acids is here! Strengthen your cells against age-related breakdown with Fatty15. Get 15% off a 90-day Starter Kit Subscription at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/fatty15⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • PALEOVALLEY - "Paleovalley has a wide variety of extraordinary products that are both healthful and delicious,” says Dr. Drew. "I am a huge fan of this brand and know you'll love it too!” Get 15% off your first order at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/paleovalley⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • VSHREDMD – Formulated by Dr. Drew: The Science of Cellular Health + World-Class Training Programs, Premium Content, and 1-1 Training with Certified V Shred Coaches! More at https://drdrew.com/vshredmd • THE WELLNESS COMPANY - Counteract harmful spike proteins with TWC's Signature Series Spike Support Formula containing nattokinase and selenium. Learn more about TWC's supplements at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twc.health/drew⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 「 MEDICAL NOTE 」 Portions of this program may examine countervailing views on important medical issues. Always consult your physician before making any decisions about your health. 「 ABOUT THE SHOW 」 Ask Dr. Drew is produced by Kaleb Nation (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://kalebnation.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠) and Susan Pinsky (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/firstladyoflov⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠e⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠). This show is for entertainment and/or informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment. Learn more about your ad choices. Visit megaphone.fm/adchoices

Book 101 Review
Book 101 Review, in its fifth season, features Dalton Sizemore a molecular biologist, science communicator, and caregiver. as my guest.

Book 101 Review

Play Episode Listen Later Oct 3, 2025 23:47


Dalton SizemoreBiology with Heart, Humor, and a DrawlI'm Dalton — a molecular biologist, science communicator, and caregiver. I hold a BS and MS in Cell and Molecular Biology from Appalachian State University, where I focused on cancer biology, virology, and immunology. My research explored how viruses like VSV might be used to disrupt the immune processes that help cancer metastasize. I also hold a graduate certificate in clinical psychology, which helps me bridge the gap between the science of the body and the realities of the human experience.But the truth is, everything I've done in science is rooted in something far more personal.I'm a survivor of childhood abuse. My father left when I was young, and my mother — who raised me on her own — endured two severely abusive relationships: one during my childhood, and another while I was in high school and starting college. Those years shaped me deeply. They taught me what it means to live in chaos and still push forward, to carry pain and still protect others, and to learn, even when nothing in your life feels safe.While I was earning my degrees, I was also a full-time caregiver. My mom nearly died from a MRSA infection that turned into a kidney crisis. My grandmother is disabled and was one of the first people in the U.S. to receive an implantable defibrillator. My sister has a seizure disorder that renders her disabled. At 22, I was managing emergency care, making medical decisions, studying biochemistry and organic chemistry, and trying not to fall apart.Want to be a guest on Book 101 Review? Send Daniel Lucas a message on PodMatch, here: https://www.podmatch.com/hostdetailpreview/17372807971394464fea5bae3 Hosted on Acast. See acast.com/privacy for more information.

Authentic Biochemistry
MS XII Authentic Biochemistry Podcast 01Octoberr25 Dr Daniel J Guerra

Authentic Biochemistry

Play Episode Listen Later Oct 2, 2025 64:32


ReferencesInt J Mol Sci. 2022 Jul 8;23(14):7592. Exp Mol Med . 2024 Apr;56(4):946-958.Front Endocrinol (Lausanne). 2020 Jul 29;11:483.Nature Structural & Molecular Biology 2025 .32, pages431–440 Kath, T. 1970.Memories of Love Chicago II https://music.youtube.com/watch?v=GFjWeUnt6nY&si=mHjfAhTlwVyXE0ZMSchubert, F. 1829. Standchen 4 D 957https://music.youtube.com/watch?v=pJf-XXTBEqs&si=2fMoDFFsHz_i1H0GSimon, P. 1966. Scarborough Fare.https://music.youtube.com/watch?v=-Jj4s9I-53g&si=OA7lBVGkiPXlPpoJLennon/McCartney. 1966. Rainhttps://music.youtube.com/watch?v=nrEgtOeJGzQ&si=D1lQwT-_ck2pBD_X

Voices, a Podcast from the Seneca Valley School District
Digital Dangers: What Families Need to Know with Ms. Angie Kotula, Dr. Lou Nagy and School Resource Officer Chris Miller

Voices, a Podcast from the Seneca Valley School District

Play Episode Listen Later Oct 2, 2025 26:39 Transcription Available


In this episode, we're talking about online dangers that students can potentially face, including sextortion and cyberbullying. We'll hear from school leaders and one of our School Resource Officers about how these issues impact students, ways to stay safe, the importance of understanding your digital footprint, and what steps to take if you or someone you know is targeted.IN THIS EPISODE, WE WILL REVIEWSextortion, cyberbullying and the misuse of AI-generated images Legal consequences of sextortion and cyberbullyingSteps students, parents and educators can take to prevent sextortion and how to respond if it happensWays students can protect themselves from online scams, predators or sextortion Reporting tools SprigeoTakeitdownNational Center for Missing & Exploited Children OverviewSPECIAL GUESTSRyan Gloyer Middle School (RGMS) librarian Ms. Angie Kotula, tech facilitator Dr. Lou Nagy and School Resource Officer Chris Miller Ms. Angie Kotula is in her 18th of teaching at Seneca Valley. She has taught second grade, 7th grade English and is currently the librarian at RGMS. Ms. Kotula graduated of both Robert Morris University and Edinboro University where she received a Bachelor of Science and Master's in Education. She holds certifications in K-6 Elementary Education, 7-9 and 7-12 English, K-12 Reading Specialist, and K-12 Library.  Additionally, she has received numerous online-safety certifications from the National Center for Missing and Exploited Children and has taken a graduate level course in digital citizenship.  She is a current member of the digital citizenship committee at Seneca Valley and has years of experience teaching middle school students about online safety alongside local law enforcement and building colleagues. Dr. Lou Nagy is currently in his 37th year at Seneca Valley.  He began his career at SV as a Biology Teacher for General Biology, Advanced Biology and AP Biology. As Seneca Valley began incorporating technology into the classroom, Dr. Nagy left teaching Biology and became one of the first technology facilitators, a role that he continues in today.  He earned his Bachelor of Science degree in Biology and Molecular Biology from Westminster College and obtained his Master of Arts in Teaching as well as his doctorate with a concentration in Instructional Technology from the University of Pittsburgh. In addition to his tenure at Seneca Valley, Dr. Nagy has taught Biology at Highlands High School and Duquesne University in the department of Educational Technology and Leadership.  Officer Chris Miller has been a Police Officer employed by the Jackson Township Police Department for the last 17 years. He attended the University of Pittsburgh and is a graduate of the Indiana University of Pennsylvania Police Academy Class #63.

Medicus
Ep 163 | Cultural Humility in Pediatrics

Medicus

Play Episode Listen Later Oct 1, 2025 48:56


Cultural humility is a lifelong practice of self-reflection, openness, and respect for the diverse backgrounds of the families we serve. Unlike cultural competence, which can imply mastering knowledge about “other cultures,” cultural humility emphasizes curiosity, listening, and shared decision-making. In pediatrics, this is especially important because care involves both the child and the family, whose cultural values strongly shape health beliefs and practices.Today's discussion is an opportunity to reflect together: how do we approach cultural humility in pediatrics, and what steps can we take to deepen it in our daily practice?Dr. Ana Aguilar, DO is originally from Loveland, OH. She went to Transylvania University where she did not major in Blood-Sucking and Shadow-Walking, but instead earned a dual degree in Molecular Biology and Anthropology. She attended Ohio University Heritage College of Osteopathic Medicine and is a very recent Loyola graduate, now completing a chief year with her best friend and co-chief, Dr. Sana Moqeet, MD. In her spare time, Ana enjoys reading, solving puzzles, writing and denying vampire allegations.Episode produced by: Deborah ChenEpisode recording date: 09/11/2025www.medicuspodcast.com | medicuspodcast@gmail.com | Donate: http://bit.ly/MedicusDonate

Intelligent Design the Future
Douglas Axe on the Human Element in Science

Intelligent Design the Future

Play Episode Listen Later Sep 26, 2025 17:54


On this episode of ID the Future selected out of our vault, host Eric Metaxas begins a conversation with biologist and professor Dr. Douglas Axe on The Eric Metaxas show. Axe is the Maxwell Professor of Molecular Biology at Biola University, the founding Director of Biologic Institute, the founding Editor of BIO-Complexity, and the author of Undeniable: How Biology Confirms Our Intuition That Life is Designed. In Part 1, Dr. Axe shares how he lost his research position in Cambridge during a season of political controversy over Darwinian evolution in the UK. He also shares what he learned from his experiments in protein evolution that cast doubt on the neo-Darwinian explanation for life. This is Part 1 of a two-part conversation. Source

Speaking of Mol Bio
From seed to cDNA―lessons learned from plant RNA workflows

Speaking of Mol Bio

Play Episode Listen Later Sep 24, 2025 19:35


In this Mol Bio Minutes episode, Dr. Will Barnes, a plant biologist turned senior sales training specialist at Thermo Fisher Scientific, reflects on his time at the bench and the molecular lessons learned along the way. Will dives deep into the difficulties of RNA work in plant systems—carbohydrate contamination, genomic DNA carryover, secondary structure—and how these hindered everything from cloning and expression analysis to sequencing and qPCR.Through real-world anecdotes, he explains how high-quality reagents and systems helped him troubleshoot and resolve recurring issues, ultimately saving time and improving data reliability. He advocates for prioritizing upstream steps like RNA integrity and reverse transcription fidelity instead of chasing fixes at the end of the workflow.Listeners will leave with a deeper appreciation for the critical role of sample prep in molecular biology workflows and why investing in better tools pays off in cleaner data, greater confidence, and fewer headaches. Will's experience is a relatable reminder that smarter choices lead to better science.Helpful resource links mentioned in this episode:Learn about molecular cloning workflows and Gateway cloning solutionsExplore a variety of resources on reverse transcriptionTaqMan vs SYBR Chemistry for Real-Time PCRUsing MagMAX kits for automated nucleic acid extractionLearn more about, or order,SuperScript IV VILO Master MixExplore RNA/DNA quantification solutions, including Qubit and Nanodrop instruments----------------------------------------------------------------------------------------------Limited time promotional offer – Be one of the first 75 listeners to spend $500 and get 40% off all eligible reverse transcriptase, plastics, enzymes, and cloning reagents. Visit thermofisher.com/sombpromo for full detailsEnter promo code CAZDUA in the U.S.A.Enter promo code CZ7F19 in Canada Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.

Sapio with Buck Joffrey
154: Is Telomere Length Shortening the Master Switch of Aging?

Sapio with Buck Joffrey

Play Episode Listen Later Sep 22, 2025 47:34


In this episode, Dr. Bill Andrews joins Dr. Buck Joffrey to discuss the critical role of telomeres and telomerase in aging and cellular health. He explains how telomeres shorten with each cell division, leading to aging and cellular senescence. Dr. Andrews emphasizes the importance of inducing telomerase to potentially reverse aging and shares insights from his research on telomerase inducers. He also addresses the challenges in longevity research, the relationship between telomeres and the hallmarks of aging, and the potential of gene therapy. The conversation concludes with a discussion on lifestyle factors that can influence aging and the future of aging research. Learn more about Dr. Bill Andrews: https://sierrasci.com/dr-bill-andrews/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/

Burn Your Draft
#71: Bags of Chemistry with Amelie Andreas '24, Biochem and Molecular Biology

Burn Your Draft

Play Episode Listen Later Sep 18, 2025 29:05


Amelie started out in the biology department at Reed because she wanted to study bacteria and living things, but then she got a chance to start learning from the biochemists on the faculty. They helped her build the bridge from chemistry to life, which led her to switch her major from biology to biochemistry and molecular biology. Amelie was also the second student producer for Burn Your Draft, working with us from 2021–22, and it was a delight to get to talk to her. Reed community members can read Amelie's thesis, “MntR: The Mastermind of Manganese Ion Homeostasis” online in the Electronic Theses Archive: https://rdc.reed.edu/i/9e05e465-0d21-4fb0-9de1-e6d4d2bf1349 Explore more interviews with Reed College alumni on our website: reed.edu/burnyourdraft

Timber University
Forest Health Happenings in the US South | 35

Timber University

Play Episode Listen Later Sep 10, 2025 38:46


In this episode, we are joined by Dr. Kristy McAndrew from Mississippi State University. Dr. McAndrew will walk us through the ins and outs of Brown spot needle blight, a fungal disease that infects pine needles, leading to premature needle loss, stunted growth, and long-term stress that increases a tree's vulnerability to other pests and pathogens, and provide an update on Emerald Ash Borer presence in the region.  Dr. McAndrew is a forest health specialist at Mississippi State University in the Forestry Department. Kristy has a Bachelor of Science in Forestry and a Bachelor of Science in Fisheries & Wildlife, both from the University of Missouri in Columbia, MO, and also completed a Master's and PhD at Mississippi State University in the Department of Biochemistry, Molecular Biology, Entomology, and Plant Pathology.  For more on brown spot needle blight, see this recent article and publication from the Arkansas Division of Agriculture. www.uaex.uada.edu/media-resources/news/2025/august/08-18-2025-ark-UAM-needle-blight.aspx If you have questions, feel free to contact us at timberuniversity@gmail.com  

Speaking of Mol Bio
Seeding scientific equity through access

Speaking of Mol Bio

Play Episode Listen Later Sep 10, 2025 37:02


In this episode of Speaking of Mol Bio, host Steve Lewis speaks with Dr. Melissa Wu, co-founder and CEO of Seeding Labs, a nonprofit that's redefining global scientific access. Dr. Wu shares the inspiring story of how Seeding Labs helps institutions in developing nations build research infrastructure by redistributing surplus laboratory equipment from partners like Thermo Fisher Scientific.With an innovative model that connects equipment donors in the global North with universities and institutes across Africa, Asia, and Latin America, Seeding Labs enables groundbreaking science in places where opportunity is limited but talent is abundant. Dr. Wu highlights examples like the Malawi University of Science and Technology, whose graduates are now staffing the country's first hospital microbiology labs, and a Beninese research team using donated PCR equipment to improve the yield of indigenous crops like the miracle berry.More than a logistics operation, Seeding Labs is also fostering scientific networks, reversing brain drain, and giving researchers confidence, courage, and agency. Dr. Wu offers a compelling vision of an equitable global scientific ecosystem, and shares how listeners can get involved—whether by donating equipment, funds, or simply spreading the word. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.

Project Oncology®
Expanding the Risk Profile: Genetic Insights Into Lung Cancer in Non-Smokers

Project Oncology®

Play Episode Listen Later Sep 10, 2025


Guest: Paola Marignani, PhD, EMBA While smoking remains a key risk factor for lung cancer, up to 25 percent of cases occur in people who have never smoked, leaving significant gaps in our understanding of causation and diagnostics. Dr. Paola Marignani explores emerging discoveries in gene variants unique to never-smokers, uncovered through single-cell RNA sequencing and machine learning. Dr. Marignani is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University in Halifax, Novia Scotia, and she spoke about this topic at the 2025 World Conference on Lung Cancer.

This is Democracy
This is Democracy – Episode 306: Federal Science Funding

This is Democracy

Play Episode Listen Later Sep 9, 2025 26:07


This week, we have Prof. John Beckett Wallingford to discuss the current landscape of federal science funding, and the importance of science in American industry and society. We set the scene with a reading of The Polio Vaccine, Chatham, Virginia, 1964, by Claudia Emerson. John Beckett Wallingford is a developmental biologist with three decades of experience.  He is the Mr. and Mrs. Robert P. Doherty Jr. Regents Chair in Molecular Biology and a Professor in the Dept. of Molecular Biosciences at the University of Texas at Austin.  Since 2003, his laboratory has sought to understand how form and function arise in embryos using advanced microscopy, systems biology, and biomechanics. Wallingford's research explores animal models and collaborates with human geneticists to understand human birth defects. He is writing a forthcoming book about embryos:  In the Beginning.

Project Oncology®
Unlocking Tumor Complexity: Single-Cell RNA Sequencing in Lung Cancer

Project Oncology®

Play Episode Listen Later Sep 9, 2025


Guest: Paola Marignani, PhD, EMBA Single-cell RNA sequencing is transforming our understanding of tumor heterogeneity in primary lung cancers by offering insights far beyond traditional bulk sequencing. In this program, Dr. Paola Marignani explores how advanced machine learning enables faster, more precise profiling of genetic diversity, predictive modeling for recurrence and drug resistance, and personalized treatment strategies. Dr. Marignani is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University in Halifax, Novia Scotia, and she spoke about this topic at the 2025 World Conference on Lung Cancer.

The Rx Bricks Podcast
Physiology of the Renal Tubular System

The Rx Bricks Podcast

Play Episode Listen Later Sep 2, 2025


Looking for more information on this topic? Check out the Physiology of the Renal Tubular System brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts.  It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks.  After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.

The Climbing Doctor Podcast
Optimizing Motor Control and Motor Learning in Climbing - Joe Manoles

The Climbing Doctor Podcast

Play Episode Listen Later Sep 1, 2025 48:10


In this conversation, Jared Vagy and Joe Manoles discuss the concepts of motor learning and motor control, particularly in the context of climbing. They explore key terminology, the stages of motor learning, and practical applications for climbers. The discussion also delves into personal challenges faced by climbers, types of practice and feedback, and the importance of understanding individual learning styles. The conversation emphasizes the significance of feedback mechanisms and learning strategies in improving climbing performance. Joe Manoles's Bio Dr. Joe Manoles PT, DPT is a healthcare professional in Bend, Oregon specializing in the treatment, recovery, and performance of climbers and mountain athletes. His care is characterized by his compassion, attention to detail, and dedication to holistic care. He believes strongly in the core pillars of health as a need for all human beings and their direct influence on our experience on Earth. In order to understand the complexity of health systems, Joe received a B.S in Biochemistry and Molecular Biology with a minor in Microbiology. He continued his education at Oregon State University-Cascades receiving his Doctorate of Physical Therapy and has sought out continuing educational mentorship and coursework through a variety of trusted resources in the climbing community including The Climbing Doctor, The Climb Clinic, and Camp 4 Human Performance. These days, if he isn't working on his new business Dissonance Performance and Physical Therapy, he is spending time with his spouse Taylor Manoles and their 4 year-old border collie Finn, climbing, snowboarding, and exploring the breathtaking beauty of central Oregon. Chapters 00:00 Introduction to Motor Learning and Control   02:54 Understanding Key Terminology   06:00 Stages of Motor Learning in Climbing   08:45 Applying Motor Learning to Climbing Techniques   12:06 Overcoming Challenges in Climbing Skills   14:58 Types of Practice and Feedback in Climbing   18:02 The Role of Feedback in Skill Development   21:09 Conclusion and Summary of Key Concepts   24:41 Exploring Climbing Preferences and Techniques   27:03 The Learning Process in Climbing   30:13 Feedback Mechanisms in Climbing   35:03 Error-Driven vs. Errorless Learning   39:23 Guided vs. Discovery Learning   40:38 Understanding Bandwidth in Feedback   42:13 Final Thoughts on Motor Learning in Climbing Links and Resources for This Episode:

Flyover Conservatives
Only 17% of Millennials Hit These 5 Adult Milestones—Why?; What If Childhood Trauma Is Behind Your Health Problems? - Dr. Troy Spurrill | FOC Show

Flyover Conservatives

Play Episode Listen Later Aug 27, 2025 96:19


Tonight at 8:30pm CST, on the Flyover Conservatives show we are tackling the most important things going on RIGHT NOW from a Conservative Christian perspective! Tonight at 8:30pm CST, on the Flyover Conservatives show we are tackling the most important things going on RIGHT NOW from a Conservative Christian perspective! TO WATCH ALL FLYOVER CONTENT: www.theflyoverapp.comTO WATCH ALL FLYOVER CONTENT: www.theflyoverapp.comFollow and Subscribe on YouTube: https://www.youtube.com/@TheFlyoverConservativesShowFollow and Subscribe on YouTube: https://www.youtube.com/@TheFlyoverConservativesShowhttps://www.youtube.com/@TheFlyoverConservativesShowTo Schedule A Time To Talk To Dr. Dr. Kirk Elliott Go To To Schedule A Time To Talk To Dr. Dr. Kirk Elliott Go To ▶ https://flyovergold.com▶ https://flyovergold.comOr Call 720-605-3900 Or Call 720-605-3900 ► Receive your FREE 52 Date Night Ideas Playbook to make date night more exciting, go to www.prosperousmarriage.com► Receive your FREE 52 Date Night Ideas Playbook to make date night more exciting, go to www.prosperousmarriage.comDr. Troy Spurrill is the founder and CEO of Synapse Center for Health and Healing.  He started Synapse over 26 years ago with a vision to bring an integrative approach to healthcare through functional medicine, making Synapse an internationally known center for true health.Dr. Troy Spurrill is the founder and CEO of Synapse Center for Health and Healing.  He started Synapse over 26 years ago with a vision to bring an integrative approach to healthcare through functional medicine, making Synapse an internationally known center for true health.He received a Bachelor's of Science in Molecular Biology from the University of Manitoba, and a Doctorate of Chiropractic from Northwestern Health Sciences University.  He has extensive training in Functional Neurology, Nutrition, and Applied Kinesiology. Dr. Troy is an author and international lecturer on wellness and brain based healing.  He received a Bachelor's of Science in Molecular Biology from the University of Manitoba, and a Doctorate of Chiropractic from Northwestern Health Sciences University.  He has extensive training in Functional Neurology, NutSend us a message... we can't reply, but we read them all!Support the show► ReAwaken America- text the word FLYOVER to 918-851-0102 (Message and data rates may apply. Terms/privacy: 40509-info.com) ► Kirk Elliott PHD - http://FlyoverGold.com ► My Pillow - https://MyPillow.com/Flyover ► ALL LINKS: https://sociatap.com/FlyoverConservatives

Sex and Psychology Podcast
Episode 425: What Determines Our Sexual Orientation?

Sex and Psychology Podcast

Play Episode Listen Later Aug 22, 2025 34:48


Why are some people straight while others are gay or bisexual? What determines our sexual orientation anyway? Today, we're going to be diving into what we've learned about the biological origins of our sexuality from decades of scientific research. As you'll see, there's not a simple and easy story—it doesn't boil down to something like a “gay gene.” It's way more complex than that! I am joined once again by Nathan Lents, a Professor of Biology at John Jay College, where he is the director of the Cell and Molecular Biology program. His research lab studies human genetic evolution and forensic DNA technology. He also writes popular science articles and is the author of the new book The Sexual Evolution: How 500 Millions Years of Sex, Gender, and Mating Shape Modern Relationships. Some of the specific topics we explore include: Is same-sex attraction genetic? How can two people who share 100% of the same DNA have different sexual orientations? When researchers are studying sexual orientation, should they be looking at attraction, identity, behavior, or all of the above? Why is having more older brothers linked to greater odds of homosexuality in men? What other biological factors are associated with sexual orientation? You can check out Nathan’s website to learn more about his work. Got a sex question? Send me a podcast voicemail to have it answered on a future episode at speakpipe.com/sexandpsychology. *** Thank you to our sponsors!  Load Boost is a supplement designed to improve the taste, volume, and overall health of your semen. If you want to elevate your sexual performance, check out Load Boost from VB Health. Visit loadboost.com to learn more and save 10% with code JUSTIN. The Kinsey Institute at Indiana University has been a trusted source for scientific knowledge and research on critical issues in sexuality, gender, and reproduction for over 75 years. Be sure to register for the Sex and Aging Symposium, which will take place on October 4, 2025. *** Want to learn more about Sex and Psychology? Click here for previous articles or follow the blog on Facebook, Twitter, or Bluesky to receive updates. You can also follow Dr. Lehmiller on YouTube and Instagram. Listen and stream all episodes on Apple, Spotify, Google, or Amazon. Subscribe to automatically receive new episodes and please rate and review the podcast! Credits: Precision Podcasting (Podcast editing) and Shutterstock/Florian (Music). Image created with Canva; photos used with permission of guest.

Build Your Network
Make Money with Biohacking | Dr. Jeff Gross

Build Your Network

Play Episode Listen Later Aug 21, 2025 31:30


 Dr. Jeff Gross — Board-certified neurological surgeon, biochemist, biohacker, founder of Celebrate Regenerative Medicine, and longevity/biohacking consultant based in Las Vegas & Southern California. Medical & Health Longevity Background: Dr. Gross trained at UC Berkeley (Biochemistry & Molecular Biology), George Washington University School of Medicine, UC Irvine (Neurosurgery), and UNM (Spinal Biomechanics). He has decades of frontline experience in spine surgery, sports injuries, regenerative medicine, and now consults on biohacking and longevity. Biohacking & Longevity: Biohacking is essentially circles back to ancient wellness wisdom (eat well, sleep, exercise)—but enhanced by modern science (measuring phytonutrients, leveraging tech like red light, hyperbaric therapy, protein timing, etc). Emphasizes that “prevention” is still the number one defense against the four top causes of death in Western countries; early proactive screening and lifestyle habits remain critical. There is increasing crossover between “traditional medicine” and “naturopathic”/“functional” approaches—Dr. Gross sees this convergence as positive and overdue, but notes resistance still exists in mainstream medicine. Emerging Business Opportunities in the Wellness Space: IV centers, cryotherapy, and retail biohacking clinics (hyperbaric O2, red light therapy, peptides, weight loss clinics, etc.) are booming, especially in health-conscious cities. Low-barrier options: health coaching, nutrition consulting, affiliate/online influencer businesses—Dr. Gross notes people he knows personally earning seven figures as wellness affiliates. Innovations: Short-form EMS (electro-muscular stimulation) workouts, “blood flow restriction” exercise systems, and more. Cancer screening clinics: Now possible with advanced genomics and blood-testing—these are in demand but not widely available through traditional doctors/insurance, opening more avenues for direct-to-consumer providers. Supplementation & Biohacking Basics: “Non-negotiables” for almost everyone: Vitamin D3 (& often K2): Most people are deficient; optimal blood levels promote longevity, reduce inflammation, and lower all-cause mortality. Magnesium: Especially at night for recovery and cellular repair. Creatine: Improves muscle mass, heart health, and brain health; well correlated with longevity. Probiotics: Modern lifestyles make gut health challenging—good probiotic support is important. Nicotine: Can be a cognitive enhancer in low doses and proper delivery (gum/patch, NOT smoking)—but is highly addictive. Other Business/Money Ideas: Successful affiliate and influencer businesses for those passionate about health and wellness. Emphasizes supplement sales (with high trust and real value), personalized coaching, and education are evergreen opportunities. Industry Critique: Criticizes health insurance as a “legal mafia,” noting it often adds cost and hassle while limiting real preventive care. Encourages listeners to be their “own best advocate” for health—don't rely only on five-minute mainstream doctor visits. Connect with Dr. Jeff Gross: https://recellebrate.com/

Smologies with Alie Ward
PROTEINS & DNA with Raven “The Science Maven” Baxter

Smologies with Alie Ward

Play Episode Listen Later Aug 21, 2025 25:14


This one's got it all: teeny tiny cellular factories, mitochondrial relevancy, what big smelly vats of poop have to do with curing cancer, how many trips to the sun your unravelled DNA could make, and mysteries of the brain. Dr. Raven The Science Maven has a background in molecular biology and a Ph.D in Science Communication, which she puts to work while Alie generally does her best to suppress high pitched noises of excitement. Learn to appreciate your proteins and pick up some noodle analogies while you're here. That's so Maven!Follow Raven on Instagram and BlueskyVisit Raven's website and YouTube channelA donation went to Project for AwesomeFull-length (*not* G-rated) Molecular Biology episode + tons of science linksMore kid-friendly Smologies episodes!Become a patron of Ologies for as little as a buck a monthOlogiesMerch.com has hats, shirts, hoodies, totes!Follow Ologies on Instagram and BlueskyFollow Alie Ward on Instagram and TikTokSound editing by Mercedes Maitland of Maitland Audio Productions, Jarrett Sleeper of MindJam Media, and Steven Ray MorrisMade possible by work from Noel Dilworth, Susan Hale, Jacob Chaffee, Kelly R. Dwyer, Aveline Malek and Erin TalbertSmologies theme song by Harold Malcolm

Speaking of Mol Bio
Customization is key―tailoring RT-qPCR for modern assays

Speaking of Mol Bio

Play Episode Listen Later Aug 20, 2025 14:45


In this Mol Bio Minutes mini-episode, Thermo Fisher Scientific's Agnė Žiupkaitė takes listeners on a journey through the evolving world of RNA assay development—focusing specifically on 1-Step RT-qPCR. She outlines the critical considerations for assay developers, including enzyme speed, robustness, and the growing demand for customizable reagents that meet both technical and regulatory needs.Highlighting Thermo Fisher's SuperScript reverse transcriptase family—particularly the Lyo-ready SuperScript III Flash RT—Agnė explains how innovations in enzyme design have broken past bottlenecks in assay workflow, enabling reverse transcription in under a minute. She also explores the power of customization, from labeling and fill formats to enzyme formulation changes and glycerol-free options that support microfluidic platforms and lyophilization.Agnė offers practical insight into how raw material suppliers can serve as collaborative partners, not just vendors. She emphasizes the importance of commercial rights, scalability, and regulatory readiness when sourcing components for commercial assay kits. Whether you're an OEM kit developer or a scientist building the next molecular breakthrough, this episode is packed with actionable insights to improve efficiency, reliability, and speed.Helpful resource links mentioned in this episode:Learn more about raw materials for molecular diagnosticsOrder Lyo-ready SuperScript III Flash TranscriptaseVisit this page to expand your knowledge of reverse transcription Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.

Sex and Psychology Podcast
Episode 424: Are Humans Made To Be Monogamous?

Sex and Psychology Podcast

Play Episode Listen Later Aug 19, 2025 35:29


Are human beings made for monogamy or non-monogamy? This is a popular subject of debate. While some argue that humans evolved for monogamy in order to ensure parental investment in our offspring, others argue that humans evolved to be non-monogamous because it increases the odds of reproductive success and genetic diversity in our species. So which is it? That's what we're going to be talking about today. I am joined by Nathan Lents, a Professor of Biology at John Jay College, where he is the director of the Cell and Molecular Biology program. His research lab studies human genetic evolution and forensic DNA technology. He also writes popular science articles and is the author of the new book The Sexual Evolution: How 500 Millions Years of Sex, Gender, and Mating Shape Modern Relationships. Some of the specific topics we explore include: What’s the difference between social monogamy and sexual monogamy? How common are social and sexual monogamy in both humans and animals, and how often do they overlap? Can research on other primates shed light on how human mating strategies evolved? Can someone’s brain chemistry predispose them to being monogamous or non-monogamous? You can check out Nathan’s website to learn more about his work. Got a sex question? Send me a podcast voicemail to have it answered on a future episode at speakpipe.com/sexandpsychology. *** Thank you to our sponsors!  Load Boost is a supplement designed to improve the taste, volume, and overall health of your semen. If you want to elevate your sexual performance, check out Load Boost from VB Health. Visit loadboost.com to learn more and save 10% with code JUSTIN. Passionate about building a career in sexuality? Check out the Sexual Health Alliance. With SHA, you’ll connect with world-class experts and join an engaged community of sexuality professionals from around the world. Visit SexualHealthAlliance.com and start building the sexuality career of your dreams today. *** Want to learn more about Sex and Psychology? Click here for previous articles or follow the blog on Facebook, Twitter, or Bluesky to receive updates. You can also follow Dr. Lehmiller on YouTube and Instagram. Listen and stream all episodes on Apple, Spotify, Google, or Amazon. Subscribe to automatically receive new episodes and please rate and review the podcast! Credits: Precision Podcasting (Podcast editing) and Shutterstock/Florian (Music). Image created with Canva; photos used with permission of guest.

The Learning Scientists Podcast
Episode 92: Science Communication with Leonardo Feletto

The Learning Scientists Podcast

Play Episode Listen Later Aug 14, 2025 38:31


In Episode 92, Althea talks with Leonardo Feletto. Leo has a PhD in Molecular Biology and is now a science teacher. But most important for this particular episode, Leo is a science communicator.

Hearts Of Gold
Ep 159 Embracing Cultural Diversity: Aanya Kasera's Journey to the Girl Scout Gold Award

Hearts Of Gold

Play Episode Listen Later Aug 7, 2025 24:39 Transcription Available


Aanya discusses her project, "Sharing the Joys of Cultural Diversity," which focused on fostering understanding and appreciation of cultural differences among children in her community. Aanya highlights two key components of her project: facilitating discussions about cultural identity in local schools and creating a children's book that details her own experiences as an immigrant from India. She reflects on her personal struggles with cultural acceptance and the importance of embracing one's identity. Join us as Aanya shares her insights and the impact of her work in promoting cultural diversity. More about Annya: Aanya is a sophomore at Princeton University studying Molecular Biology on the pre medicine track. For her Gold Award, Aanya created a cultural education and appreciation initiative in her community to encourage children to develop their global literacy and spark their love for diversity. Aanya published a children's book, Samosas with Saanvi, to share how she grew to love her cultural identity, capture the joys of cultural diversity, and portray the emotional journey behind acceptance. The mission of her project was to bridge the cultural literacy gap she noticed in her community, allow children to discover their own cultural identities, and foster meaningful community connections. At Princeton, Aanya is involved in The Daily Princetonian Podcast and STEM Research Journalism teams, the Undergraduate Student Government Mental Health and Diversity, Equity, and Inclusion Committees, and the Council on Science & Technology Student Advisory Board. She is very interested in scientific and medical research, working with the IMDEA Materials Institute to learn more about biomaterials and regenerative medicine, as well as Fundação Oswaldo Cruz in virology and immunology. She loves to continue sharing her book and cultural story with family, friends, and community members. In her freetime, you may find her reading the newest fantasy or mystery novel, singing karaoke with her little sister, or playing with her shih tzu poodle Daisy. https://www.amazon.com/Samosas-Saanvi-Aanya-Kasera/dp/B0CCCKNZW3

The Rx Bricks Podcast
Pericardial Effusion and Cardiac Tamponade

The Rx Bricks Podcast

Play Episode Listen Later Aug 5, 2025


Looking for more information on this topic? Check out the Congenital Adrenal Hyperplasia brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts.  It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks.  After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.

The Rx Bricks Podcast
Blood Pressure Control: Foundations and Frameworks (Re-release)

The Rx Bricks Podcast

Play Episode Listen Later Jul 29, 2025


Looking for more information on this topic? Check out the Thrombotic Disorders: Foundations and Frameworks brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts.  It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks.  After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.

People Behind the Science Podcast - Stories from Scientists about Science, Life, Research, and Science Careers
823: Probing Protein Dynamics from Molecular Switches to Shape-Changing Viral Particles - Dr. Ganesh Anand

People Behind the Science Podcast - Stories from Scientists about Science, Life, Research, and Science Careers

Play Episode Listen Later Jul 28, 2025 41:11


Dr. Ganesh Anand is an Associate Professor of Chemistry as well as Biochemistry and Molecular Biology at The Pennsylvania State University (or Penn State University) at the University Park campus. He is also an elected Board Member of the International Society for Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS). Research in Ganesh's lab examines molecular switches. He wants to know how molecules interact with one another and how they switch from one state to another. These tiny molecular switches act almost like electrical switches turning on and off the functions of different molecules. He also does research on viruses and how they change shape to infect their hosts. Beyond his scientific interests, Ganesh has also been passionate about music for as long as he can remember. He takes voice lessons now and enjoys singing in choirs in his free time. He received his bachelor's degree in pharmacy and his master's degree in biological sciences from Birla Institute of Technology and Science in India. Next, Ganesh attended Rutgers University where he earned his PhD in biochemistry. Afterwards, he conducted postdoctoral research as a Howard Hughes Medical Institute Research Fellow at the University of California San Diego. Ganesh served on the faculty in the Department of Biological Sciences at the National University of Singapore for over a decade before accepting a faculty position at Penn State where he is today. His lab is recognized as a Waters World Center of Innovation in Hydrogen/Deuterium Exchange Mass Spectrometry. Ganesh is founding member and former Director of the Singapore National Laboratory for Mass Spectrometry (SingMass) and the former Vice President of the Singapore Society for Mass Spectrometry. In this interview, he shares more about his life and science.

Mind & Matter
Synapse Energetics & Fat Metabolism in the Brain | Timothy Ryan | 241

Mind & Matter

Play Episode Listen Later Jul 23, 2025 85:59


Send us a textHow brain synapses work and fuel themselves with fat.Episode Summary: Dr. Timothy Ryan talks about the high energy costs of synapses, the role of mitochondria and glycolysis, and challenge the long-held view that the brain relies solely on glucose by discussing new evidence that neurons burn fats from lipid droplets for fuel, especially during activity. The talk touches on metabolic flexibility, links to epilepsy treatments like ketogenic diets, neurodegenerative diseases, and future research on brain energy sources.About the guest: Timothy Ryan, PhD is a professor of biochemistry at Cornell University. His research focuses on the molecular mechanisms of synaptic transmission, particularly vesicle recycling and the bioenergetics that power neural communication. Discussion Points:Synapses are tiny structures with ~100 vesicles per site (on average), converting electrical signals to chemical ones.Brain tissue is energy-hungry due to trillions of synapses (in humans), relying on local mitochondria (present in only ~half of synapses) and glycolysis.Vesicles use proton pumps and transporters to concentrate neurotransmitters, requiring ATP to maintain gradients.Neurons are metabolically fragile; cutting fuel supply quickly impairs synapses.Dogma held brains don't burn fats, but new work shows neurons form lipid droplets (fat stores) that are invisible because constantly used for energy via beta-oxidation.Silencing neurons builds lipid droplets like resting muscle; activity speeds their breakdown, indicating demand-driven fat use.Inhibiting neuron-specific fat-processing enzymes accumulates droplets and induces torpor (hibernation-like state) in animals, signaling metabolic stress.Ketogenic diets aid epilepsy by shifting to ketones; fats may explain this, with potential ties to aging and neurodegeneration like Alzheimer's.Brain may be a "hybrid" fuel user (glucose + fats), with open questions on fat sources and roles in cognition or disease protection.Related episode:M&M 158: Ketosis & Ketogenic Diet: Brain & Mental Health, Metabolism, Diet & Exercise, Cancer, Diabetes | Dominic D'Agostino*Not medical advice.Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

Just Be® ~ Spiritual BOOM
181 Jerneja Tomsic~PhD Molecular Biologist: Lies within PCR Tests/DNA/Cancer/Mammograms, Killing Intuition, Socialism, Melania, Breaking Fear

Just Be® ~ Spiritual BOOM

Play Episode Listen Later Jul 23, 2025 95:39


Jerneja Tomsic is a rebellious, outspoken gal (thank goodness) who carries a PhD in Molecular Biology. Being from Slovenia (as is Melania Trump), she knows about socialism... down to the untruths of science paradigms because she is in that world, is now awake and researches. From the lies of PCR tests being effective in diagnosing Co*v*d down to the truth of DNA/double helix, cancer, mammograms, viruses and bacteria.For the "Just Be Practice," Jerneja highlights how fear is the real virus.References for the show:https://viroliegy.comConversation on breast health:https://odysee.com/@Dawn-Lester:3/Conversation-with-Robyn---Jerneja:eLinks to Jerneja:Her Rumble channel: https://rumble.com/user/Jerneja18Chat with Kevin Corbett on PCR tests for The End of COVID project:https://odysee.com/@TheEndOfCovid:3/20230706-TEOC-TEOC-SESSION-The-PCR-Tests--Dr--Jerneja-Tomsic--Dr--Kevin-Corbett-MULTICAM-CUT-2-mov-by-NA:bThe Scientific Method:https://rumble.com/v59dcal-mwk-science-1-the-scientific-method-jerneja-tomsic.htmlPeer Review:https://rumble.com/v5b8wcd-mwk-science-2-peer-review-jerneja-tomsic.html*Host Eden Koz is a soul realignment specialist utilizing such gifts as psychological empathy, intuition, psychic ability, mediumship, meditation, mindset shift, Reiki, dimensional and galactic healing, to name a few. She can also perform a spiritual Co#id Vac+ Healing as well as remote & face-to-face sessions with individuals and groups. Contact info for Eden Koz / Just Be®, LLC:Website: EdenJustBe.com Socials: Insta, FB, FB (Just Be), LinkedIn Just Be~Spiritual BOOM Podcast can be found on the audio directories: Apple Podcasts, Spotify, Amazon Music, Stitcher, iHeart Radio, TuneIn+Alexa, ...

The Rx Bricks Podcast
Diuretics: Foundations and Frameworks (Re-release)

The Rx Bricks Podcast

Play Episode Listen Later Jul 22, 2025


Looking for more information on this topic? Check out the Physiology of Diuretics brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts.  It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks.  After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.

Biotech 2050 Podcast
Ahmed Mousa, Vicore CEO, on IPF Breakthroughs, AI-Powered Drug Discovery & Global Biotech Leadership

Biotech 2050 Podcast

Play Episode Listen Later Jul 16, 2025 16:33


Synopsis: What do courtroom litigation, computational biology, and fibrosis drug development have in common? In this episode of Biotech 2050, host Alok Tayi speaks with Ahmed Mousa, CEO of Vicore Pharma, to explore his unconventional journey from biotech law to the C-suite. Ahmed shares how Vicore is advancing a first-in-class therapy targeting the angiotensin II type 2 receptor to treat idiopathic pulmonary fibrosis (IPF)—a devastating disease with limited options and poor survival. The conversation dives into how AI is reshaping drug discovery, the promise of precision in early-stage candidate design, and the regulatory and data challenges biotech must overcome. Ahmed also reflects on leading a Swedish-listed biotech as an American CEO, and how a patient-first mission continues to fuel bold innovation across continents. Biography: Ahmed Mousa is the Chief Executive Officer of Vicore Pharma (VICO.ST), where he leads the company's mission to advance angiotensin II type 2 receptor agonists for the treatment of idiopathic pulmonary fibrosis and other serious diseases. Under his leadership, Vicore continues to expand its clinical pipeline and global presence in respiratory and fibrotic diseases. Previously, Ahmed served as Senior Vice President, Chief Business Officer, and General Counsel at Pieris Pharmaceuticals (PIRS). In this role, he was the site head for the company's Boston office and oversaw business development, portfolio strategy, centralized project leadership, and quality assurance. He also led Pieris' legal and intellectual property functions, including licensing, corporate governance, and management of the company's global patent portfolio. Before joining Pieris, Ahmed was an attorney at Covington & Burling LLP, where he advised pharmaceutical and biotechnology companies on a range of regulatory and intellectual property matters. He also served as a law clerk for the U.S. Court of Appeals for the Third Circuit and began his legal career as an IP associate at Kirkland & Ellis LLP. Ahmed holds dual undergraduate degrees in Molecular Biology and Government from Cornell University, a Master's in Biotechnology from Johns Hopkins University, and a J.D. with honors from Georgetown Law, where he was Editor-in-Chief of the Georgetown Journal of International Law.

The Ripple Effect Podcast
Episode 549: The Ripple Effect Podcast (Dr. Jessica Rose | The Curse of Curiosity: PART 2)

The Ripple Effect Podcast

Play Episode Listen Later Jul 11, 2025 132:07


Dr. Jessica Rose is an artist, musician, mathematician, professional surfer, biologist, science researcher & data analysis. Dr. Rose has a Post Doc in Biochemistry at Technion Institute of Technology, Post Doc in Molecular Biology at Hebrew University of Jerusalem, PhD in Computational Biology at Bar-Ilan University, Master's in Medicine (Immunology) at Memorial University of Newfoundland, and BSc in Applied Mathematics at Memorial University of Newfoundland.DR. JESSICA ROSE:Twitter: https://twitter.com/JesslovesMJKSubStack: https://jessicar.substack.com/YouTube: https://www.youtube.com/channel/UC0EhWf2Vswdg7DwKKKZ34ngTHE RIPPLE EFFECT PODCAST:WEBSITE: http://TheRippleEffectPodcast.comWebsite Host & Video Distributor: https://ContentSafe.co/SUPPORT:PATREON: https://www.patreon.com/TheRippleEffectPodcastPayPal: https://www.PayPal.com/paypalme/RvTheory6VENMO: https://venmo.com/code?user_id=3625073915201071418&created=1663262894MERCH Store: http://www.TheRippleEffectPodcastMerch.comMUSIC: https://music.apple.com/us/album/the-ripple-effect-ep/1057436436SPONSORS:OPUS A.I. Clip Creator: https://www.opus.pro/?via=RickyVarandasUniversity of Reason-Autonomy: https://www.universityofreason.com/a/2147825829/ouiRXFoL WATCH:RUMBLE: https://rumble.com/c/therippleeffectpodcastBANNED.VIDEO: https://banned.video/channel/the-ripple-effect-podcastOFFICIAL YOUTUBE: https://www.youtube.com/@TheRippleEffectPodcastOFFICIALYOUTUBE CLIPS CHANNEL: https://www.youtube.com/@RickyVarandasTikTok: https://www.tiktok.com/@ricky.varandasLISTEN:SPOTIFY: https://open.spotify.com/show/4lpFhHI6CqdZKW0QDyOicJiTUNES: http://apple.co/1xjWmlFPodOmatic: https://www.podomatic.com/podcasts/rvtheory6CONNECT:TeleGram: https://t.me/TREpodcastX: https://x.com/RvTheory6IG: https://www.instagram.com/rvtheory6/ FB: https://www.facebook.com/TheRippleEffectPodcast/THE UNION OF THE UNWANTED: https://linktr.ee/TheUnionOfTheUnwanted

Epigenetics Podcast
The Human Cell Atlas (Sarah Teichmann)

Epigenetics Podcast

Play Episode Listen Later Jul 10, 2025 46:40


In this episode of the Epigenetics Podcast, we talked with Sarah Teichmann from the University of Cambridge about the Human Cell Atlas. In the Interview we explore Sarah Teichmann's impressive career trajectory, covering her current role as Chair of Stem Cell Medicine at the Cambridge Stem Cell Institute and Vice President of Translational Research at GlaxoSmithKline. Professor Teichmann explains her unique dual appointments, a rare arrangement that allows her to bridge academia and industry effectively. As the conversation shifts focus to computational biology, she takes us on a historical journey from her PhD work at the MRC Laboratory of Molecular Biology to the present advancements driven by next-generation sequencing and artificial intelligence methods. Professor Teichmann emphasizes that the landscape of biological research has evolved significantly, particularly in the realm of data-driven methodologies. The conversation then transitions seamlessly into her pivotal role in advancing single-cell genomics, where she discusses the motivation behind using single-cell RNA sequencing methods in her research on T cells. This technique offered unmatched insights compared to bulk sequencing techniques, allowing for a more detailed understanding of cell states and their complex interactions within tissues. A highlight of the episode is Professor Teichmann's insights on the Human Cell Atlas project, which she co-founded in 2017. She elaborates on the ambitious vision to map all human cells, likening the endeavor to the Human Genome Project. Through the atlas, researchers aim to create a detailed reference map that facilitates a deeper understanding of human health and disease. Professor Teichmann shares the collaborative efforts that led to its inception and the importance of international cooperation in scientific research. The discussion culminates with an exploration of the biggest scientific findings thus far from the Human Cell Atlas. Among the revelations, she notes the astounding complexity and diversity of cell types identified, particularly within the immune system, and the unexpected locations of certain cell types during human development. She also highlights significant discoveries related to COVID-19, demonstrating the immediate real-world impact of their work.   References https://www.humancellatlas.org The Human Cell Atlas: towards a first draft atlas Kock, K. H., Tan, L. M., Han, K. Y., Ando, Y., Jevapatarakul, D., Chatterjee, A., Lin, Q. X. X., Buyamin, E. V., Sonthalia, R., Rajagopalan, D., Tomofuji, Y., Sankaran, S., Park, M. S., Abe, M., Chantaraamporn, J., Furukawa, S., Ghosh, S., Inoue, G., Kojima, M., Kouno, T., … Prabhakar, S. (2025). Asian diversity in human immune cells. Cell, 188(8), 2288–2306.e24. https://doi.org/10.1016/j.cell.2025.02.017   Related Episodes The Discovery of Genomic Imprinting (Azim Surani)   Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

The Ripple Effect Podcast
Episode 548: The Ripple Effect Podcast (Dr. Jessica Rose | The Curse of Curiosity: Part 1)

The Ripple Effect Podcast

Play Episode Listen Later Jul 9, 2025 96:51


Dr. Jessica Rose is an artist, musician, mathematician, professional surfer, biologist, science researcher & data analysis. Dr. Rose has a Post Doc in Biochemistry at Technion Institute of Technology, Post Doc in Molecular Biology at Hebrew University of Jerusalem, PhD in Computational Biology at Bar-Ilan University, Master's in Medicine (Immunology) at Memorial University of Newfoundland, and BSc in Applied Mathematics at Memorial University of Newfoundland.DR. JESSICA ROSE:Twitter: https://twitter.com/JesslovesMJKSubStack: https://jessicar.substack.com/YouTube: https://www.youtube.com/channel/UC0EhWf2Vswdg7DwKKKZ34ngTHE RIPPLE EFFECT PODCAST:WEBSITE: http://TheRippleEffectPodcast.comWebsite Host & Video Distributor: https://ContentSafe.co/SUPPORT:PATREON: https://www.patreon.com/TheRippleEffectPodcastPayPal: https://www.PayPal.com/paypalme/RvTheory6VENMO: https://venmo.com/code?user_id=3625073915201071418&created=1663262894MERCH Store: http://www.TheRippleEffectPodcastMerch.comMUSIC: https://music.apple.com/us/album/the-ripple-effect-ep/1057436436SPONSORS:OPUS A.I. Clip Creator: https://www.opus.pro/?via=RickyVarandasUniversity of Reason-Autonomy: https://www.universityofreason.com/a/2147825829/ouiRXFoL WATCH:RUMBLE: https://rumble.com/c/therippleeffectpodcastBANNED.VIDEO: https://banned.video/channel/the-ripple-effect-podcastOFFICIAL YOUTUBE: https://www.youtube.com/@TheRippleEffectPodcastOFFICIALYOUTUBE CLIPS CHANNEL: https://www.youtube.com/@RickyVarandasTikTok: https://www.tiktok.com/@ricky.varandasLISTEN:SPOTIFY: https://open.spotify.com/show/4lpFhHI6CqdZKW0QDyOicJiTUNES: http://apple.co/1xjWmlFPodOmatic: https://www.podomatic.com/podcasts/rvtheory6CONNECT:TeleGram: https://t.me/TREpodcastX: https://x.com/RvTheory6IG: https://www.instagram.com/rvtheory6/ FB: https://www.facebook.com/TheRippleEffectPodcast/THE UNION OF THE UNWANTED: https://linktr.ee/TheUnionOfTheUnwanted

Mind & Matter
Circadian Biology: Genetics, Behavior, Metabolism, Light, Oxygen & Melatonin | Joseph Takahashi | 237

Mind & Matter

Play Episode Listen Later Jul 4, 2025 112:33


Send us a textHow our biological clocks shape biology from the molecular to behavioral level.Episode Summary: Dr. Joseph Takahashi discusses circadian rhythms, exploring their biological basis, from molecular mechanisms to their impact on metabolism and health; the discovery of circadian clock genes; role of the suprachiasmatic nucleus, and how light, feeding, and oxygen influence these rhythms. The conversation highlights practical implications, such as the effects of artificial light and meal timing on health, and touches on emerging research linking stronger circadian clocks to longevity.About the guest: Joseph Takahashi, PhD is a renowned neuroscientist at UT Southwestern Medical Center, where he leads research on circadian clock genes.Discussion Points:The suprachiasmatic nucleus in the hypothalamus acts as the brain's central clock, syncing with light via the retina.Key circadian genes like CLOCK and BMAL regulate thousands of genes, especially those involved in metabolism, impacting health outcomes.Internal desynchronization, when brain and organ clocks misalign (e.g., from eating at night), can lead to metabolic issues like pre-diabetes.In mice, eating at the right time (night for nocturnal animals) extends lifespan by up to 35% under caloric restriction, compared to 10% with spread-out feeding.Artificial light, especially blue light at night, disrupts melatonin and circadian rhythms, while natural sunlight supports healthy eye development.Melatonin, a darkness-signaling hormone, is best for resetting rhythms (e.g., jet lag) at low doses, not as a sedative, and U.S. supplements vary widely in quality.Oxygen-sensing proteins interact with circadian clock components, hinting at links between altitude, metabolism, and health.Learning and memory show diurnal variations, with better performance at certain times, influenced by circadian modulation of synaptic activity.A stronger circadian clock, created genetically in mice, led to 16% longer lifespan and resistance to weight gain (unpublished research).Related episode:M&M 202: Why Do Animals Sleep? | Vlad Vyazovskiy*Not medical advice.Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

Mind & Matter
Cell Biology: Cytoskeleton, Self-Assembly & Self-Organization, Wound Healing | Bill Bement | 236

Mind & Matter

Play Episode Listen Later Jun 29, 2025 91:14


Send us a textCellular self-organization, cytoskeleton dynamics, and membrane wound healing.Episode Summary: Cell Biologist Dr. Bill Bement explains the dynamic world of the cell cortex, discussing how actin filaments and microtubules drive processes like cell division and wound healing through self-assembly and self-organization; energy dynamics of these processes; the role of rho GTPases in patterning; the implications for diseases such as cancer and muscular dystrophy, using vivid analogies and video demonstrations to make complex concepts accessible.About the guest: Bill Bement, PhD is a cell biology professor at the University of Wisconsin-Madison, where he has studied cellular processes for over 30 years. He leads a lab focused on the cell cortex, investigating cell division and repair. His work emphasizes self-organization and cytoskeletal dynamics, contributing to insights into diseases like muscular dystrophy.Discussion Points:The cell cortex, the outer layer of a cell, includes the plasma membrane & underlying proteins like actin & myosin, which enable dynamic shape changes.Actin filaments self-assemble without energy input, growing & shrinking to facilitate cell movement and division, while microtubules, stiffer hollow tubes, aid in chromosome separation.Self-organization in cells, driven by energy-dependent feedback loops, creates complex patterns like mitotic spindles.Cellular wound healing involves concentric rings of rho GTPases and actin, closing wounds rapidly, a process critical for surviving natural damage from mechanical stress or toxins.Energy costs of cytoskeletal rearrangements are significant but likely less than protein synthesis, though precise measurements remain challenging.Cancer metastasis may rely on enhanced cell repair, allowing metastatic cells to survive mechanical damage while squeezing through tissues.Muscular dystrophy involves excessive damage or impaired repair, highlighting the importance of cell repair mechanisms.Bement's lab is developing tools for synthetic self-organization, aiming to manipulate cellular processes to address repair deficits in diseases.Related episode:M&M 220: Cell Death, Oxidative Stress, PUFAs & Antioxidants | Pamela Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

Conspiracy Theories
Are Octopuses Aliens??

Conspiracy Theories

Play Episode Listen Later Jun 11, 2025 36:31


In 2018, a peer-reviewed article published in Progress in Biophysics and Molecular Biology suggested the theory that octopuses could have extraterrestrial origins. As in, they're not regular Earthlings. The 33 scientists who authored the paper say, the octopus could have arrived on Earth, in some form, on board a celestial body – like an asteroid. Most of the scientific community disagreed. Experts said octopuses are alien-like, but there are clues to suggest they experienced a normal, Earth-bound evolution. However…they might hold clues about what alien behavior would look like. Today, we're joined by researcher Dominic Sivitilli, who tells us what studying octopus cognition can teach us about alien intelligence. Keep up with us on Instagram @theconspiracypod! Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Human Upgrade with Dave Asprey
The Anti-Aging Chamber That Rewinds Your Biological Clock|Dr. Jason Sonners : 1281

The Human Upgrade with Dave Asprey

Play Episode Listen Later May 15, 2025 49:05


Your cells are starving. Not for food—but for oxygen. In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Jason Sonners, world-renowned hyperbaric expert and regenerative medicine pioneer, to reveal how controlled oxygen under pressure is becoming one of the most powerful tools in anti-aging and performance science. You'll learn how hyperbaric oxygen therapy (HBOT) triggers stem cell activation, rewires your epigenome, boosts mitochondrial energy, and reverses biological aging—if you use it the right way. Jason shares breakthrough findings from his latest PhD research comparing low- and high-pressure chambers, with surprising results on inflammation, telomeres, cognitive performance, and recovery speed. This is next-gen longevity—measurable, stackable, and customizable. From sleep upgrades and HRV boosts to stacking HBOT with fasting, methylene blue, or red light, this episode dives into what it takes to oxygenate your biology at the deepest level. You'll Learn: • How hyperbaric oxygen therapy (HBOT) triggers stem cell regeneration and cellular repair • Why mild-pressure chambers may be more powerful than you think• What HBOT does to inflammation, brain fog, and biological aging markers • How to stack HBOT with fasting, red light, and methylene blue for amplified results • What Dr. Sonners' PhD research reveals about oxygen pressure and genetic expression • The truth about oxygen toxicity—and how to avoid the common mistakes • How elite performers use HBOT for brain optimization, recovery, and resilience ** Get 30% of yourr tickets to the Biohacking conference by going to https://biohackingconference.com/2025 and use code ‘OXYHEALTH' ** Thank you to our sponsors! -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Jason's Website – www.hbotusa.com • OxyHealth Website: https://www.oxyhealth.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:59 Intro • 03:14 New research on aging and oxygen • 05:39 Mild vs. hard-shell chambers • 13:05 HBOT for longevity and stem cells • 16:43 How to optimize your sessions • 22:35 Best therapies to stack with HBOT • 25:40 Oxygen delivery and safety • 26:43 Altitude and chamber effects • 30:01 Key benefits of hyperbaric therapy • 34:22 Supplement synergy and timing • 37:25 Pressure and oxygenation findings • 39:27 Medical vs. welding oxygen • 44:57 Safety myths and toxicity risks • 47:39 Future of biohacking with oxygen See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.