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Dr. Carla Finkielstein is an Associate Professor of Biological Sciences within the Biocomplexity Institute of Virginia Tech. She is also Director of the Integrated Cellular Response Laboratory at Virginia Tech, a Member of the Executive Committee of the Susan G. Komen Blue Ridge Board, and past member of the Board of Directors of the Virginia Breast Cancer Foundation. Carla is interested in understanding the mechanisms cells use to measure time to regulate cell division. She hypothesizes that cancer may occur when the clocks within cells signal to the cell to divide too frequently. Carla's goal is to understand how this process occurs so that we can fix the issue, detect the problem early to provide treatment, or prevent it from happening. Outside of science, Carla's favorite hobby is cooking. She loves making new and creative dishes that bring together different colors, flavors, and taste profiles. Cooking is relaxing for her, and it's fun to share dishes she creates with her friends and family. In addition, Carla enjoys reading a wide variety of books about history. Carla received her B.S. and Ph.D. both in Molecular Biology from the University of Buenos Aires in Argentina. Afterwards, she worked as a Research Associate at the Howard Hughes Medical Institute at the University of Colorado Health Sciences Center. Carla then conducted further postdoctoral research at the University of Colorado Health Sciences Center before joining the faculty at Virginia Tech. Carla has been recognized for her research accomplishments with the L. Chely Award for Best PhD Thesis, a Howard Hughes Institute Fellowship for Research, an American Heart Association Postdoctoral Fellowship, the Karin Noss Scholarship for Research Advocacy in Breast Cancer, the Susan G. Komen Award for Junior Investigators, and a National Science Foundation CAREER Award. In our interview Carla shared more about her life and science.
พบกับไลฟ์ #108: สรุปหนังสือดี Why We Die: The New Science of Aging and The Quest for Immortality โดย Prof.Venki Ramakrishnan (ตอนที่ 4) วันศุกร์ 20 ก.พ. 2569 เวลา 20.00 น. สวัสดีค่ะน้องๆที่รักของพี่ปุ๋มทุกคน หนังสือเล่มนี้ให้ความเข้าใจความตายและการมีอายุขัยที่ยืนยาว แปลกมากที่เป็นหนังสือที่เกี่ยวกับความตายแต่กลับทำให้พี่อ่านได้อย่างต่อเนื่องไม่เบื่อเลยค่ะ ข้อเสียมีอยู่อย่างเดียว อ่านแล้วต้องใช้เวลาจับใจความสำคัญอีกรอบเพื่อนำมาทำเป็นสไลด์ประกอบการทำไลฟ์ค่ะ หนังสือเล่มนี้มีพื้นฐานมาจากการที่ Prof.Venki Ramakrishnan มีความเข้าใจ Ribosome ซึ่งเป็น organelle ที่อยู่ภายในเซลล์ มีความสำคัญยิ่งยวด เพราะเป็นที่สร้างโปรตีนเกือบทุกชนิดในร่างกาย พี่ชอบการมองความตายจากมุมมองของ Prof.Venki ที่แตกต่างจากนักวิทยาศาสตร์ความชราท่านอื่นจากการที่เขาเชี่ยวชาญ ribosome มาก เป็นหนังสือดีที่ควรจะนำมาสรุปให้จบทั้งเล่ม Prof. Venki Ramakrishnan ได้รับรางวัลโนเบลในสาขาเคมี ในปี พ.ศ.2552 ร่วมกับ Thomas A Steitz และ Ada E. Yonath สำหรับการศึกษาโครงสร้างและหน้าที่ของไรโบโซม ซึ่งทำหน้าที่ในการอ่านข้อมูลทางพันธุกรรมเพื่อสร้างโปรตีนที่ถูกระบุ ไรโบโซมมีความซับซ้อนเชิงระดับโมเลกุลเพราะมีราวห้าแสนอะตอมที่ประกอบเป็นไรโบโซม เขาดำรงตำแหน่งหัวหน้ากลุ่มวิจัยชีววิทยาโมเลกุลของสภาการวิจัยทางการแพทย์ในวิทยาเขตการแพทย์เคมบริดจ์ตั้งแต่ พ.ศ.2538 และเป็นสมาชิกของวิทยาลัยทรินิตี มหาวิทยาลัยเคมบริดจ์ และเคยดำรงตำแหน่งนายกราชสมาคม (Royal Society) ตั้งแต่ พ.ศ.2558 จนถึง พ.ศ.2563 Prof.Venki เกิดและเติบโตที่ประเทศอินเดีย จบปริญญาตรีสาขาฟิสิกส์ เมื่ออายุ 19 ปี เขาเดินทางมาเรียนต่อระดับปริญญาเอกที่สหรัฐอเมริกาในสาขาฟิสิกส์ จากนั้นความสนใจของเขาก็เปลี่ยนเป็นชีววิทยา เขาใช้ชีวิต 30 ปีในสหรัฐอเมริกาก่อนจะย้ายมาสหรัฐราชอาณาจักรในปี 2542 เพื่อทำงานที่ MRC Laboratory of Molecular Biology ในวิทยาเขตการแพทย์เคมบริดจ์ ในปัจจุบันเค้าเป็นหัวหน้ากลุ่มงานวิจัย พี่ปุ๋มสะสมหนังสือที่เกี่ยวข้องกับความชราไว้จำนวนมาก และก็ว่างเว้นจากการทำไลฟ์สรุปหนังสือดีมานานพอสมควร ที่ให้ความสนใจหนังสือเล่มนี้เพราะ 1. Venki Ramakrishnan ได้รับรางวัลโนเบลสาขาเคมี และระบุปัญหาสำคัญในระดับชีวโมเลกุลว่า ข้อมูลทางพันธุกรรมถูกอ่านเพื่อจะสร้างโปรตีนที่เฉพาะเจาะจง ตามคำสั่งได้อย่างไร 2. Venki มีความเชื่อพร้อมหลักฐานว่า Ribosome เป็น organelle ภายในเซลล์ที่เกี่ยวข้องกับความชรา ซึ่งแตกต่างจากนักวิทยาศาสตร์ความชราท่านอื่นที่ให้ความสำคัญกับ DNA หนังสือมีทั้งหมด 12 บท พี่ทำไลฟ์ไปแล้วสามตอนค่ะ เป็นหนังสือที่แค่ฟังเล็คเชอร์ของ Prof.Venki ก็ตื่นเต้นแล้วค่ะ พบกันในตอนที่ 4 ของหนังสือเล่มนี้ วันศุกร์ 20 ก.พ. 2569 เวลา 20.00 น. ค่ะ ❤️ #หาคำตอบสุขภาพจากงานวิจัยไม่ใช่จากเรื่องเล่า #FatOutHealthspans
Geneticist Adrian Woolfson shares his insights on designing life with artificial biological intelligence, the possibility of creating new species, and the responsibility that comes with rewriting the rules of evolution. Adrian Woolfson is the co-founder of Genyro, a California-based biotechnology company specialising in synthetic genome design and construction. Born in London, he studied medicine at Balliol College, Oxford, and was formerly the Charles and Katherine Darwin Research Fellow at Darwin College, Cambridge, working at the MRC Laboratory of Molecular Biology. He is the author of the critically acclaimed Life Without Genes: The History and Future of Genomes and An Intelligent Person's Guide to Genetics. He has authored over 160 scientific papers, book chapters, reviews, and patents, and is a regular contributor to the Wall Street Journal and Science magazine. Bonus episode recorded live from the World Governments Summit 2026 at the House of Impact on 03 February 2026. Full-Video Version: https://youtu.be/ejHgoD1Wt5I ABOUT THE HOST Luke Robert Mason is a British-born futures theorist who is passionate about engaging the public with emerging scientific theories and technological developments. He hosts documentaries for Futurism, and has contributed to BBC Radio, BBC One, The Guardian, Discovery Channel, VICE Motherboard and Wired Magazine. CREDITS In Partnership with the Dubai Future Foundation Producer & Host: Luke Robert Mason Join the conversation on Facebook, Instagram, and Twitter at @FUTURESPodcast Follow Luke Robert Mason on Twitter at @LukeRobertMason Subscribe & Support the Podcast at http://futurespodcast.net
สรุปหนังสือดี Why We Die: The New Science of Aging and The Quest for Immortality โดย Prof.Venki Ramakrishnan (ตอนที่ 3) วันเสาร์ 14 ก.พ. 2569 (ต้อนรับวันแห่งความรัก ❤️) เวลา 20.00 น. สวัสดีค่ะน้องๆที่รักของพี่ปุ๋มทุกคน พี่ปุ๋มเคยทำไลฟ์หนังสือดีเล่มนี้ไว้แล้ว 2 ตอน คือไล์ฟ#76 และ 77 (วางลิงคไว้ในคอมเมนท์) เมื่อเดือน มิ.ย. 2567 ทำไปได้ 3 บท หมดแรงอ่าน 555 หนังสือเล่มนี้ให้ความเข้าใจความตายและการมีอายุขัยที่ยืนยาว มีพื้นฐานมาจากการที่ Prof.Venki Ramakrishnan มีความเข้าใจ Ribosome ซึ่งเป็น organelle ที่อยู่ภายในเซลล์ มีความสำคัญยิ่งยวด เพราะเป็นที่สร้างโปรตีนเกือบทุกชนิดในร่างกาย เห็นสมควรที่จะนำมาทำให้จบทั้งเล่ม ถึงแม้จะใช้เวลา 1.5 ปีก็ตาม
Applications are now open for the Marine Institute's 2026 Bursary Programme, which provides third-level students with practical work experience at Ireland's national marine research and development agency. The Marine Institute's Bursary Programme has been operating for over 30 years, providing essential career development and support, and inspiring the next generation of marine scientists and experts. The programme equips third-level students with essential skills and necessary experience to become ocean leaders and marine champions of the future. The Marine Institute is committed to supporting a culture of high performance. This is driven by our people, whose skills, experience and passion for the marine are crucial to our continued delivery of highly impactful services for government and other stakeholders. The Bursary Programme provides undergraduates with a unique opportunity to meet fellow students from other third-level colleges as well as work with experts in their field, helping participants to form future networks in the marine sector. The Bursary Programme is aimed at undergraduate students of Universities and Institutes for Higher Education, both National and International. To participate in the programme, undergraduate students must have completed two years of study in a relevant discipline by the beginning of June 2026. Glenn Nolan, Bursary Programme Lead and Director of Marine Environment and Food Safety Services, said,?"For more than 30 years, the Marine Institute Bursary Programme has enabled undergraduate students to develop their skills and strengthen their knowledge of the marine sector. Participating students emerge equipped to make informed decisions early in their studies about the marine and maritime careers they would like to pursue." Successful candidates will work with full-time Marine Institute staff on critical work programmes, including Marine and Freshwater Fisheries, Oceanography, Machine Learning/AI, Marine Chemistry, Molecular Biology, Marine Spatial Planning, Remote Sensing, Web Development, Socio-economics, and Corporate Services. The bursaries are based at Marine Institute facilities in Oranmore, Co. Galway, and Newport, Co. Mayo. To apply for the Marine Institute's 2026 Bursary Programme: View the bursary titles available. Select the two bursary positions that interest you the most, in order of preference. Complete the onlineapplication formandsubmitas per the instructions:?https://forms.office.com/ Application Deadline Date is 16:00, Friday, 27th?February 2026. More about Irish Tech News Irish Tech News are Ireland's No. 1 Online Tech Publication and often Ireland's No.1 Tech Podcast too. You can find hundreds of fantastic previous episodes and subscribe using whatever platform you like via our Anchor.fm page here: https://anchor.fm/irish-tech-news If you'd like to be featured in an upcoming Podcast email us at Simon@IrishTechNews.ie now to discuss. Irish Tech News have a range of services available to help promote your business. Why not drop us a line at Info@IrishTechNews.ie now to find out more about how we can help you reach our audience. You can also find and follow us on Twitter, LinkedIn, Facebook, Instagram, TikTok and Snapchat.
This episode was originally released on December 13, 2022Stop the presses! New research shows that viruses locked in the Arctic permafrost for thousands of years have the potential to infect present-day organisms. Accompanied with a warming planet, this issue is really starting to thaw out. So what can brave scientists and institutions on the frontlines of tracking diseases do about it? And how can understanding our genomic history with diseases over thousands of years better prepare us in the fight to overcome them?Dr. Kaylee Byers starts our journey by slinking into a disease-tracking genomics lab at Simon Fraser University to meet Dr. Michael Trimble and Dr. Will Hsiao to understand the challenge of outpacing the rapid evolution of viruses. Then she pops across the ocean to speak with Dr. Birgitta Evengård and Dr. Jean-Michel Claverie about whether the Pandora's box of ancient diseases frozen in the arctic have the potential to become the next global outbreak as temperatures warm. Plus, we unearth ancient burial sites in Vietnam with Dr. Melandri Vlok, to investigate how climate change exacerbates the tension between human health and pathogens.Special thanks to Dr. Will Hsiao and Dr. Michael Trimble for allowing us to record with them at Simon Fraser University.Resources:1. Infection control in the new age of genomic epidemiology | British Columbia Centre for Disease Control Public Health Laboratory2. The permafrost pandemic: could the melting Arctic release a deadly disease | Unearthed3. Viral spillover risk increases with climate change in High Arctic lake sediments | The Royal Society4. Healthy ecosystems for human and animal health: Science diplomacy for responsible development in the Arctic | The Nordic Centre of Excellence5. Understanding and Responding to Global Health Security Risks from Microbial Threats in the Arctic: Proceedings of a Workshop | National Academies of Science, Engineering, Medicine6. Next pandemic may come from melting glaciers, new data shows | The Guardian7. Scientists Revived Ancient 'Zombie Viruses' Frozen For Eons in Siberia | Science Alert8. A 48,500-year-old virus has been revived from Siberian permafrost | NewScientist9. Anthrax outbreak in Siberia | euro news10. CBC News: The National | Russia invades Ukraine | Canadian Broadcast Corporation (CBC)11. National Geographic: Explorer Directory, Melandri Vlok | National Geographic12. Paleoepidemiological Considerations of Mobility and Population Interaction in the Spread of Infectious Diseases in the Prehistoric Past | Bioarchaeology International13. The Epidemiological Transition: A Theory of the Epidemiology of Population Change | Milbank Memorial Fund14. Forager and farmer evolutionary adaptations to malaria evidenced by 7000 years of thalassemia in Southeast Asia | nature portfolio15. CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database | Department of Molecular Biology and Biochemistry, Simon Fraser University
How do you build an organization that can absorb change, learn from failure, and keep patients at the center—even when the science is uncertain? Nelly Viseux shares lessons from over 20 years in biotech and a decade leading cell and gene therapy development.Nelly discusses how she structured a 100-person CMC organization at Regeneron to balance innovation with operational execution, why documenting your assumptions is critical to managing risk, and what it really takes to maintain resilience when you're literally holding patient lives in your hands.A few of Nelly's key takeaways:Resilience is adaptability—build organizations that absorb and anticipate change rather than resist itSeparate innovation from execution with intentional gates for when new approaches are ready to implementDocument your assumptions so you can revisit decisions effectively when circumstances changeFailure is a process problem, not a personal one—root cause analysis should improve systems, not assign blameData is the common language that aligns scientists, regulators, and stakeholdersEveryone is a leader in cell therapy—manufacturing and QC teams hold patient lives in their handsAbout Nelly ViseuxNelly Viseux is Vice President of Cell Therapies Development, Manufacturing, Supply & Quality at Regeneron, leading a 100-person organization supporting autologous cell therapy programs. She has over 20 years of biotechnology experience spanning large pharma (Shire, Biogen, Baxter) and startups, working across cell and gene therapies, biologics, and nanoparticles. Her accomplishments include building a Phase 1 cell therapy manufacturing facility that achieved 100% cGMP success and first IND submission within two years. She holds a Ph.D. in Biochemistry and Molecular Biology from University of Lille and is a member of the Society for Immunotherapy of Cancer and the American Society of Gene & Cell Therapy.About The FDA GroupThe FDA Group helps life science organizations rapidly access the industry's best consultants, contractors, and candidates. Our resources assist in every stage of the product lifecycle—from clinical development to commercialization—with a focus on staff augmentation, auditing, remediation, QMS, and other specialized project work in Quality Assurance, Regulatory Affairs, and Clinical Operations. Learn more: https://www.thefdagroup.com/
In this episode, Giovanni Piedimonte, MD, FAAP, FCCP, Professor of Pediatrics, Biochemistry, and Molecular Biology at Tulane University School of Medicine, discusses how artificial intelligence is transforming research, clinical care, and academic medicine. He also discusses the risks, ethical challenges, and workforce implications health systems must prepare for as AI adoption accelerates.
******Support the channel******Patreon: https://www.patreon.com/thedissenterPayPal: paypal.me/thedissenterPayPal Subscription 1 Dollar: https://tinyurl.com/yb3acuuyPayPal Subscription 3 Dollars: https://tinyurl.com/ybn6bg9lPayPal Subscription 5 Dollars: https://tinyurl.com/ycmr9gpzPayPal Subscription 10 Dollars: https://tinyurl.com/y9r3fc9mPayPal Subscription 20 Dollars: https://tinyurl.com/y95uvkao ******Follow me on******Website: https://www.thedissenter.net/The Dissenter Goodreads list: https://shorturl.at/7BMoBFacebook: https://www.facebook.com/thedissenteryt/Twitter: https://x.com/TheDissenterYT This show is sponsored by Enlites, Learning & Development done differently. Check the website here: http://enlites.com/ Dr. Coleen Murphy is James A. Elkins Jr. Professor in the Life Sciences, and Professor of Molecular Biology and Director of the Lewis-Sigler Institute for Integrative Genomics at Princeton University. She is the author of How We Age: The Science of Longevity. In this episode, we focus on How We Age. We discuss the science of aging, what we can learn from it, why we age, and what we can learn from animal models and centenarians. We also talk about longevity pathways, and transgenerational effects. We discuss whether intermittent fasting works. We talk about the role of DNA repair and cell replacement. We discuss whether the gut microbiome plays a role in aging. Finally, we talk about the current state of longevity biotech, and how to approach new developments.--A HUGE THANK YOU TO MY PATRONS/SUPPORTERS: PER HELGE LARSEN, JERRY MULLER, BERNARDO SEIXAS, ADAM KESSEL, MATTHEW WHITINGBIRD, ARNAUD WOLFF, TIM HOLLOSY, HENRIK AHLENIUS, ROBERT WINDHAGER, RUI INACIO, ZOOP, MARCO NEVES, COLIN HOLBROOK, PHIL KAVANAGH, SAMUEL ANDREEFF, FRANCIS FORDE, TIAGO NUNES, FERGAL CUSSEN, HAL HERZOG, NUNO MACHADO, JONATHAN LEIBRANT, JOÃO LINHARES, STANTON T, SAMUEL CORREA, ERIK HAINES, MARK SMITH, JOÃO EIRA, TOM HUMMEL, SARDUS FRANCE, DAVID SLOAN WILSON, YACILA DEZA-ARAUJO, ROMAIN ROCH, YANICK PUNTER, CHARLOTTE BLEASE, NICOLE BARBARO, ADAM HUNT, PAWEL OSTASZEWSKI, NELLEKE BAK, GUY MADISON, GARY G HELLMANN, SAIMA AFZAL, ADRIAN JAEGGI, PAULO TOLENTINO, JOÃO BARBOSA, JULIAN PRICE, HEDIN BRØNNER, FRANCA BORTOLOTTI, GABRIEL PONS CORTÈS, URSULA LITZCKE, SCOTT, ZACHARY FISH, TIM DUFFY, SUNNY SMITH, JON WISMAN, WILLIAM BUCKNER, LUKE GLOWACKI, GEORGIOS THEOPHANOUS, CHRIS WILLIAMSON, PETER WOLOSZYN, DAVID WILLIAMS, DIOGO COSTA, ALEX CHAU, CORALIE CHEVALLIER, BANGALORE ATHEISTS, LARRY D. LEE JR., OLD HERRINGBONE, MICHAEL BAILEY, DAN SPERBER, ROBERT GRESSIS, JEFF MCMAHAN, JAKE ZUEHL, MARK CAMPBELL, TOMAS DAUBNER, LUKE NISSEN, KIMBERLY JOHNSON, JESSICA NOWICKI, LINDA BRANDIN, VALENTIN STEINMANN, ALEXANDER HUBBARD, BR, JONAS HERTNER, URSULA GOODENOUGH, DAVID PINSOF, SEAN NELSON, MIKE LAVIGNE, JOS KNECHT, LUCY, MANVIR SINGH, PETRA WEIMANN, CAROLA FEEST, MAURO JÚNIOR, 航 豊川, TONY BARRETT, NIKOLAI VISHNEVSKY, STEVEN GANGESTAD, TED FARRIS, HUGO B., JAMES, JORDAN MANSFIELD, CHARLOTTE ALLEN, PETER STOYKO, DAVID TONNER, LEE BECK, PATRICK DALTON-HOLMES, NICK KRASNEY, RACHEL ZAK, DENNIS XAVIER, CHINMAYA BHAT, AND RHYS!A SPECIAL THANKS TO MY PRODUCERS, YZAR WEHBE, JIM FRANK, ŁUKASZ STAFINIAK, TOM VANEGDOM, BERNARD HUGUENEY, CURTIS DIXON, BENEDIKT MUELLER, THOMAS TRUMBLE, KATHRINE AND PATRICK TOBIN, JONCARLO MONTENEGRO, NICK GOLDEN, CHRISTINE GLASS, IGOR NIKIFOROVSKI, AND PER KRAULIS!AND TO MY EXECUTIVE PRODUCERS, MATTHEW LAVENDER,SERGIU CODREANU, AND GREGORY HASTINGS!
In this episode, Giovanni Piedimonte, MD, FAAP, FCCP, Professor of Pediatrics, Biochemistry, and Molecular Biology at Tulane University School of Medicine, discusses how artificial intelligence is transforming research, clinical care, and academic medicine. He also discusses the risks, ethical challenges, and workforce implications health systems must prepare for as AI adoption accelerates.
Send us a textDr. Christopher Buck, Ph.D. ( https://cbuck.substack.com/ ) is Senior Investigator, Laboratory of Cellular Oncology, And Head, Tumor Virus Molecular Biology Section, Center for Cancer Research, at the U.S. National Cancer Institute ( https://ccr.cancer.gov/staff-directory/christopher-b-buck ).Dr. Buck's lab focuses on the virion proteins of a family of viruses called polyomaviruses, and their research ranges from basic investigation of the mechanisms through which polyomaviruses infect cells to translational development of virus-like particle vaccines. They also maintain an active interest in discovering new virus species, with the goals of uncovering human disease associations and understanding the evolutionary history of cancer-causing viruses.Dr. Buck received a bachelor's degree in Molecular Cellular and Developmental Biology from the University of Colorado at Boulder and a Ph.D. from the Johns Hopkins School of Medicine. Dr. Buck's graduate research in Dr. Robert Siliciano's lab focused on the translation and immunogenicity of the HIV-1 capsid protein Gag. For his graduate work, Dr. Buck received the Alicia Showalter Reynolds Award. In 2001, Dr. Buck began post-doctoral training in the Lab of Cellular Oncology, where he developed systems for producing human papillomavirus (HPV)-based gene transfer vectors (pseudoviruses). His work using HPV vectors ranged from basic studies of HPV virion structure and morphogenesis to translational research identifying candidate topical microbicides for blocking HPV transmission. For his work in these areas, Dr. Buck, and his mentors, Drs. John Schiller and Doug Lowy, shared the 2006 Norman P. Salzman Award. In 2007, Dr. Buck joined the faculty of the NCI's Center for Cancer Research as an Investigator. In 2013, he shared a second Salzman Award in recognition of his mentoring of Dr. Rachel Schowalter. Dr. Buck was awarded tenure in 2014.#ChristopherBuck #CellularOncology #TumorVirus #MolecularBiology #NationalCancerInstitute #Pseudovirus #Papillomavirus #Capsid #Polyomaviruses #OralVaccines #YeastProducedAntigens #MucosalImmunology #FermentedBeverages #BeerBasedVaccines #STEM #Innovation #Science #Technology #Research #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #Podcasting #ViralPodcastSupport the show
Dr. Jessica Rose, PhD, MSc, BSc, is a Senior Fellow specializing in Computational Biology from Canada. She holds a Bachelor's Degree in applied mathematics and a master's degree in Immunology from Memorial University of Newfoundland, and a PhD in Computational Biology from Bar Ilan University. Dr. Rose has completed two post-doctoral degrees in Molecular Biology from the Hebrew University of Jerusalem, and in Biochemistry from the Technion Institute of Technology. She is best known for her contributions to public health and safety related to the COVID-19 injectable products, and her analyses of pharmacovigilance databases like VAERS. In this episode, Drs. Brian and Jessica talk about… (00:00) Intro (04:57) Dr. Jessica's upbringing, personality, and scientific pursuits (09:41) Covid vaccines, natural immunity, and bodily autonomy of individuals (19:50) The research of Kevin McKernan on DNA in vials of COVID-19 vaccines (27:39) The composition and production of Covid mRNA vaccines (33:04) National health regulation agencies and Covid vaccine DNA contamination (35:54) Lipid nanoparticles in mRNA vaccines and how they impact human health (44:22) Vaccine injuries due to spike protein proliferation and how the spike protein ruins the human immune system (54:38) Spike protein detox therapies (01:01:12) Fascia release (01:03:07) Cholesterol, gal bladder health, and nutrition (01:07:54) Fasting, autophogy, and the microbiome (01:11:33) Peer review and post-peer review attacks on valid research (01:21:53) Outro For more information, please see the links below. Thank you for listening! Links: Resources Mentioned in this Episode: Jules Horn (Fascia Release): https://www.youtube.com/@Jules_horn Science Guardians (post-peer review group): https://x.com/SciGuardians Dr. Jessica Rose: Research: https://www.researchgate.net/profile/Jessica-Rose-24 Why does DNA remain in vials of COVID-19 mRNA Shots?: https://rumble.com/v74rdvs-why-does-dna-remain-in-vials-of-covid-19-mrna-shots.html What Jessica Rose Knows: Dr. Jessica Rose on DarkHorse: https://rumble.com/v5q0zl8-what-jessica-rose-knows-dr.-jessica-rose-on-darkhorse.html Dr. Brian Lenzkes: Arizona Metabolic Health: https://arizonametabolichealth.com/ Low Carb MD Podcast: https://www.lowcarbmd.com/ HLTH Code: HLTH Code Promo Code: METHEALTH • • HLTH Code Website: https://gethlth.com
In this episode of Ordinarily Extraordinary: Conversations with Women in STEM, host Kathy Nelson sits down with Dr. Elizabeth Mendes, a newly minted PhD and postdoctoral researcher whose work focuses on rare and aggressive pediatric cancers.Dr. Mendes recently completed her PhD at Duke University, where she spent over five years researching rhabdomyosarcoma, a rare childhood soft-tissue cancer. Her goal: identify new biological targets that could one day lead to better, more effective treatments for children. Kathy and Liz explore not only the science behind pediatric cancer research, but also the deeply human reasons that drive this work.What We Talk About in This EpisodeWhat pediatric sarcomas are—and why they're so challenging to treatLiz breaks down complex cancer biology in an approachable way, explaining how sarcomas differ from more common cancers and why their ability to “change form” makes them particularly dangerous.A non-traditional path into scienceFrom archaeology and zoology to teaching middle school math and science, Liz shares how curiosity—and not a straight line—ultimately led her to molecular biology, cancer research, and a PhD.Choosing pediatric cancer researchLiz explains why she decided to focus on rare childhood cancers that receive less funding but have devastating outcomes—and how personal experiences with cancer shaped that decision.Science close to the patientWe discuss the importance (and rarity) of researchers interacting directly with patients, families, and clinicians—and how those experiences fundamentally change how science is done.Life after the PhD: postdocs, fellowships, and moving to the UKLiz shares what it's like to finish a PhD, move countries, start a new research position, and navigate life and work during a major transition.Being your whole self in STEMFrom makeup and music to mental health and social media, Liz talks about rejecting outdated stereotypes of what scientists “should” look like—and why authenticity matters for the next generation.Representation, mentorship, and science communicationLiz reflects on why visibility matters, especially for women and first-generation students, and how platforms like social media can help make science more accessible and human.A Conversation About More Than ScienceThis episode goes beyond lab work and credentials. It's a candid conversation about grief, resilience, identity, and the responsibility scientists carry—not just to discovery, but to people. Liz's story is a powerful reminder that STEM careers don't require fitting into a mold—and that compassion belongs in science.If you enjoyed this episode:Rate and review the podcast on Apple Podcasts or SpotifyFollow or subscribe so you never miss an episodeShare with a friend, colleague, or student who might need this storyHave thoughts, questions, or guest suggestions?Email us at ordinarilyextraordinarypod@gmail.com or leave a voicemail on our website.Support the show
THE RIPPLE EFFECT PODCAST:Website: http://TheRippleEffectPodcast.comSupport: https://rickyvarandas.com/support/IPAK-EDU (Empower Yourself Through Knowledge)Website: https://IPAK-EDU.org/ (use RIPPLE for 10% off)VN Alexander, PhD (aka Tori)Website: https://vnalexander.com/IG: https://www.instagram.com/rednaxelairot/AI & Transhumanism Essay: posthumousstyle.substack.comBio: Philosopher of science known for her work on Vladimir Nabokov's theory of insect mimicry evolution. She is a member of the Third Way of Evolution research group and currently works in the field of Biosemiotics. She earned her Ph.D. in 2002 in English at the Graduate Center, City University New York and did her dissertation research in teleology, evolutionary theory, and self-organization at the Santa Fe Institute. She is a Rockefeller Foundation Residency alum, a former NY Council for the Humanities scholar, and a 2020 Fulbright scholar in Russia. Books include The Biologist's Mistress: Rethinking Self-Organization in Art, Literature and Nature and several literary fiction and political science novels.Xavier A. Figueroa, Ph.D (aka Dr. X)X: https://x.com/DrXFig0708Bio: The principal scientist for EMulate Therapeutics overseeing pre-clinical research and the application of EMulate Therapeutics technology in multiple disease areas. He has more than 20 years of experience in basic and neurological clinical research, including Alzheimer's research, neuron biology, cancer research, bioengineering and biophysics. Dr. Figeuroa received his doctoral degree in Neurobiology & Behavior from the University of Washington. His doctoral training was followed by two post-doctoral fellowships within the University of Washington's Department of Bioengineering. He is currently an affiliate assistant professor in the School of Medicine at the University of Washington. Specialties include, Molecular Biology, Toxicology, Apoptosis Signaling and Regulation, Neuroscience and Neurodegenerative Expertise.Dr. James Lyons-Weiler (aka Dr. Jack)Website: https://jameslyonsweiler.com/Substack: https://popularrationalism.substack.com/Earned his PhD in Ecology, Evolution, and Conservation Biology. He has held research positions at esteemed institutions, including the University of Nevada, Reno, and the University of Pittsburgh (Dept Pathology & Dept. of Biomedical Informatics). Dr. Lyons-Weiler has an extensive portfolio of peer-reviewed articles covering various scientific disciplines such as genetics, evolution, and public health. Notably, he has conducted research on the safety of aluminum adjuvants in vaccines, focusing on their dosing and potential health implications, especially in pediatric populations. His work on “pathogenic priming” and its potential relevance to COVID-19 has also been significant. Lyons-Weiler founded the Institute for Pure and Applied Knowledge (IPAK), a research organization. He also founded IPAK-EDU, an educational platform that has educated over 1,400 students in advanced courses across a wide variety of subjects. You can find more information about these courses on their official website.
PROVA ENSAMT ELLER I FLOCK? Vi har fått in ett fång av härliga lyssnarfrågor – som att whisky smakar och doftar mer när man provar tre åt gången – eller? Dessutom: vad hände med Profilen och polisanmälan? Plus lite om samlande och Jocke Storms underbara animationer – av oss! Vad var det i glaset? Mathias hade Agitators blend, den här: https://www.systembolaget.se/produkt/sprit/agitator-40501/; David smuttade på en irländsk Stout och Box cask owners bottling från 2018, den här: https://www.whiskybase.com/whiskies/whisky/114768; Jeroen njöt av Ardnamurchan sherry cask, kanske denna av flera möjliga: https://www.whiskybase.com/whiskies/whisky/235065. Lyssnarfråga 1: Doft och smak: bäst att prova många whiskies ihop, eller en och en? David vill alltid tipsa om den här artikeln: Reed, Daniell Renee & Antti Knaapila, ”Genetics of taste and smell: poisons and pleasures”, Progress in Molecular Biology and Translational Science 94 (2010), s. 213–240. En annan intressant är: Spedding, Gary & Johnny Jeffrey, ”Smelling roses, fruit, stinky feet and much more in my glass”, Artisan Spirit 12 (Fall 2015), s. 53–58. Tillgänglig på https://issuu.com/artisanspiritmag/docs/artisanspirit_issue012_web/53 Här en bra text av Serge Valentin: ”Tasting: how to make your inherent subjectivity a little more consistent”, 5/11 2011, http://www.whiskyfun.com/archivejanuary11-1.html#0501112. Lyssnarfråga 2: Profilen, polisanmälan och hur ser whiskykulturen ut – samt lite om whisky och samlande Angus MacRaild om samlare, se till exempel: https://scotchwhisky.com/magazine/the-collectors/19979/mark-davidson-royal-mile-whiskies/ https://scotchwhisky.com/magazine/the-collectors/13769/reinhard-ellinghaus/ https://scotchwhisky.com/magazine/the-collectors/20484/helena-hugo-bredaryds-wardshus/ https://scotchwhisky.com/magazine/the-collectors/26306/bihan-yang-dalmore/ https://scotchwhisky.com/magazine/the-collectors/21665/magnus-fagerstrom-sweden/ https://scotchwhisky.com/magazine/the-collectors/16664/andy-simpson-rare-whisky-101/ https://scotchwhisky.com/magazine/the-collectors/23138/gunnar-nilsson-sweden/ Bowmore Black rock verkar ha släppts 2014: https://www.whiskybase.com/whiskies/whisky/53729 Joacim Storms underbara animeringar av En trea whisky! https://youtu.be/IgkVKZtblzA?si=lRVMvVbgfaAfMizP https://youtu.be/eaIWp5XMGu8?si=IfrS48xhn7YbkpTn https://youtu.be/zIiQCcuaRpo?si=6uNOksRFEH4sPeVv https://youtu.be/zq-9Xb6Cdds?si=jrrsZuNWVCcQzzMw Här når du oss: En trea whisky på Facebook Maila till oss på hej@entreawhisky.se Davids blogg tjederswhisky.se Följ oss på Instagram: https://www.instagram.com/entreawhisky Bli medlem! https://entreawhisky.memberful.com/checkout?plan=74960
We're back and better than ever. Season 4 of Absolute Gene-ius is officially here, and this teaser gives you a front-row seat to what's coming. From scientific puns to sneak peeks of the upcoming guest lineup, co-hosts Jordan Ruggieri and new addition Lisa Crawford set the tone for another season of engaging, educational, and entertaining molecular biology content.This season, the show expands its scope beyond digital PCR to include real-time PCR and other tools that are working together to move research forward in fields like oncology, agriculture, behavioral psychiatry, and more. Lisa brings a non-scientist's view to the show along with a deep passion for translating complex science into compelling stories. Whether it's microvesicles, stem cells, or high-containment biosafety labs, the upcoming episodes promise to be both technically informative and very human.And in classic Absolute Gene-ius fashion, we keep it fun. From how guests got into science, to what thy love most about it, and lab fail stories, the Career Corner returns with fresh energy and laughs. Expect bad puns, big discoveries, and the beautiful chaos of real-world research. Visit the Absolute Gene-ius page to learn more about the guests, the hosts, and the science we explore. Discover the Applied Biosystems QuantStudio Digital and Real-Time PCR Systems powering real-world research across neuroscience, oncology, agriculture, and more.
Does water on a hen make it more susceptible to predation? In this episode, we comb through the literature on olfactory camouflage, dissecting studies assessing correlations between nest survival, weather, and environmental conditions, and divulging into the complicated web of ecology dynamics. Strap on your science boots for this one, it's gonna be dense… Research papers referenced: Bakner, N. W., et al. (2019). Incubation recess behaviors influence nest survival of Wild Turkeys. Ecology and Evolution, 9(24), 14053-14065. Boone, W. W., et al. (2024). Robust assessment of associations between weather and eastern wild turkey nest success. The Journal of Wildlife Management, 88(2), e22524. Braun, M. S., et al. (2018). Birds, feather-degrading bacteria and preen glands: the antimicrobial activity of preen gland secretions from turkeys (Meleagris gallopavo) is amplified by keratinase. FEMS microbiology ecology, 94(9), fiy117. Conover, M. R. (2007). Predator-prey dynamics: the role of olfaction. CRC Press. Fluen, T. (2008). A comparative analysis of evolutionary changes in island birds. MSc Thesis, University of Canterbury, Christchurch. Grieves, L. A., et al. (2020). Food stress, but not experimental exposure to mercury, affects songbird preen oil composition. Ecotoxicology, 29, 275-285. Grieves, L. A., et al. (2022). Olfactory camouflage and communication in birds. Biological Reviews, 97(3), 1193-1209. Lehman, C. P., et al. (2010). Ground roost resource selection for Merriam's wild turkeys. The Journal of Wildlife Management, 74(2), 295-299. Lowrey, D. K., et al. (2001). Influences of selected weather variables on predation of wild turkey females and nest success. In Proceedings of the National Wild Turkey Symposium (Vol. 8, pp. 173-178). Potier, S., et al. (2018). Preen oil chemical composition encodes individuality, seasonal variation and kinship in black kites Milvus migrans. Journal of Avian Biology, 49(7), e01728. Reneerkens, J., et al. (2002). Sandpipers (Scolopacidae) switch from monoester to diester preen waxes during courtship and incubation, but why?. Proceedings of the Royal Society of London. Series B: Biological Sciences, 269(1505), 2135-2139. Reneerkens, J., et al. (2005). Switch to diester preen waxes may reduce avian nest predation by mammalian predators using olfactory cues. Journal of Experimental Biology, 208(22), 4199-4202. Reneerkens, J., et al. (2006). Discerning adaptive value of seasonal variation in preen waxes: comparative and experimental approaches. Acta Zoologica Sinica, 52, 272-275. Reneerkens, J., et al. (2007a). Parental role division predicts avian preen wax cycles. Ibis, 149(4), 721-729. Tuttle, E. M.,et al. (2014). Variation in preen oil composition pertaining to season,sex, and genotype in the polymorphic white-throated sparrow.Journal of ChemicalEcology40, 1025–1038. Whelan, R. J., et al. (2010). Short-chain carboxylic acids from gray catbird (Dumetella carolinensis) uropygial secretions vary with testosterone levels and photoperiod. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 156(3), 183-188. Webb, S. L., et al. (2012). Landscape features and weather influence nest survival of a ground-nesting bird of conservation concern, the greater sage-grouse, in human-altered environments. Ecological Processes, 1, 1-15. Episodes referenced: Effectiveness of trapping across game bird species | #08 Which vital rates are most important to turkey populations? | #13 Brooding and nesting cover (Part 1/2) | #29 Brooding and nesting cover (Part 2/2) | #30 Our lab is primarily funded by donations. If you would like to help support our work, please donate here: http://UFgive.to/UFGameLab Coming Soon: Wild Turkey Manager: Biology, History, & Heritage! Our newest online wild turkey training is launching soon! Be the first to know when our new course launches by signing up here! Be sure to check out our comprehensive online wild turkey course featuring experts across multiple institutions that specialize in habitat management and population management for wild turkeys. Earn up to 20.5 CFE hours! Enroll Now! Dr. Marcus Lashley @DrDisturbance, Publications Dr. Will Gulsby @dr_will_gulsby, Publications Turkeys for Tomorrow @turkeysfortomorrow UF Game Lab @ufgamelab, YouTube Want to help wild turkey conservation? Please take our quick survey to take part in our research! Do you have a topic you'd like us to cover? Leave us a review or send us an email at wildturkeyscience@gmail.com! Watch these podcasts on YouTube Please help us by taking our (quick) listener survey - Thank you! Check out the DrDisturbance YouTube channel! DrDisturbance YouTube Want to help support the podcast? Our friends at Grounded Brand have an option to donate directly to Wild Turkey Science at checkout. Thank you in advance for your support! Leave a podcast rating for a chance to win free gear! This podcast is made possible by Turkeys for Tomorrow, a grassroots organization dedicated to the wild turkey. To learn more about TFT, go to turkeysfortomorrow.org. Music by Artlist.io Produced & edited by Charlotte Nowak
Does water on a hen make it more susceptible to predation? In this episode, we comb through the literature on olfactory camouflage, dissecting studies assessing correlations between nest survival, weather, and environmental conditions, and divulging into the complicated web of ecology dynamics. Strap on your science boots for this one, it's gonna be dense… Research papers referenced: Bakner, N. W., et al. (2019). Incubation recess behaviors influence nest survival of Wild Turkeys. Ecology and Evolution, 9(24), 14053-14065. Boone, W. W., et al. (2024). Robust assessment of associations between weather and eastern wild turkey nest success. The Journal of Wildlife Management, 88(2), e22524. Braun, M. S., et al. (2018). Birds, feather-degrading bacteria and preen glands: the antimicrobial activity of preen gland secretions from turkeys (Meleagris gallopavo) is amplified by keratinase. FEMS microbiology ecology, 94(9), fiy117. Conover, M. R. (2007). Predator-prey dynamics: the role of olfaction. CRC Press. Fluen, T. (2008). A comparative analysis of evolutionary changes in island birds. MSc Thesis, University of Canterbury, Christchurch. Grieves, L. A., et al. (2020). Food stress, but not experimental exposure to mercury, affects songbird preen oil composition. Ecotoxicology, 29, 275-285. Grieves, L. A., et al. (2022). Olfactory camouflage and communication in birds. Biological Reviews, 97(3), 1193-1209. Lehman, C. P., et al. (2010). Ground roost resource selection for Merriam's wild turkeys. The Journal of Wildlife Management, 74(2), 295-299. Lowrey, D. K., et al. (2001). Influences of selected weather variables on predation of wild turkey females and nest success. In Proceedings of the National Wild Turkey Symposium (Vol. 8, pp. 173-178). Potier, S., et al. (2018). Preen oil chemical composition encodes individuality, seasonal variation and kinship in black kites Milvus migrans. Journal of Avian Biology, 49(7), e01728. Reneerkens, J., et al. (2002). Sandpipers (Scolopacidae) switch from monoester to diester preen waxes during courtship and incubation, but why?. Proceedings of the Royal Society of London. Series B: Biological Sciences, 269(1505), 2135-2139. Reneerkens, J., et al. (2005). Switch to diester preen waxes may reduce avian nest predation by mammalian predators using olfactory cues. Journal of Experimental Biology, 208(22), 4199-4202. Reneerkens, J., et al. (2006). Discerning adaptive value of seasonal variation in preen waxes: comparative and experimental approaches. Acta Zoologica Sinica, 52, 272-275. Reneerkens, J., et al. (2007a). Parental role division predicts avian preen wax cycles. Ibis, 149(4), 721-729. Tuttle, E. M.,et al. (2014). Variation in preen oil composition pertaining to season,sex, and genotype in the polymorphic white-throated sparrow.Journal of ChemicalEcology40, 1025–1038. Whelan, R. J., et al. (2010). Short-chain carboxylic acids from gray catbird (Dumetella carolinensis) uropygial secretions vary with testosterone levels and photoperiod. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 156(3), 183-188. Webb, S. L., et al. (2012). Landscape features and weather influence nest survival of a ground-nesting bird of conservation concern, the greater sage-grouse, in human-altered environments. Ecological Processes, 1, 1-15. Episodes referenced: Effectiveness of trapping across game bird species | #08 Which vital rates are most important to turkey populations? | #13 Brooding and nesting cover (Part 1/2) | #29 Brooding and nesting cover (Part 2/2) | #30 Our lab is primarily funded by donations. If you would like to help support our work, please donate here: http://UFgive.to/UFGameLab Coming Soon: Wild Turkey Manager: Biology, History, & Heritage! Our newest online wild turkey training is launching soon! Be the first to know when our new course launches by signing up here! Be sure to check out our comprehensive online wild turkey course featuring experts across multiple institutions that specialize in habitat management and population management for wild turkeys. Earn up to 20.5 CFE hours! Enroll Now! Dr. Marcus Lashley @DrDisturbance, Publications Dr. Will Gulsby @dr_will_gulsby, Publications Turkeys for Tomorrow @turkeysfortomorrow UF Game Lab @ufgamelab, YouTube Want to help wild turkey conservation? Please take our quick survey to take part in our research! Do you have a topic you'd like us to cover? Leave us a review or send us an email at wildturkeyscience@gmail.com! Watch these podcasts on YouTube Please help us by taking our (quick) listener survey - Thank you! Check out the DrDisturbance YouTube channel! DrDisturbance YouTube Want to help support the podcast? Our friends at Grounded Brand have an option to donate directly to Wild Turkey Science at checkout. Thank you in advance for your support! Leave a podcast rating for a chance to win free gear! This podcast is made possible by Turkeys for Tomorrow, a grassroots organization dedicated to the wild turkey. To learn more about TFT, go to turkeysfortomorrow.org. Music by Artlist.io Produced & edited by Charlotte Nowak
Send us a textWhat if cancer didn't have to be eradicated, but could be remembered, monitored, and controlled by the immune system itself?In this episode of Causes or Cures, Dr. Eeks speaks with Dr. Zachary Hartman, the lead researcher who revisited an extraordinary breast cancer vaccine trial conducted over 20 years ago. The trial involved a small group of women with advanced breast cancer. Women who, remarkably, are all still alive today.By analyzing their blood decades later, the research team discovered that these women still carried immune cells capable of recognizing their cancer, suggesting durable immune memory lasting more than two decades. (Study link here.)We discuss:The original breast cancer vaccine trial and what it was designed to do, in plain languageWhat it was like to discover that the women from the trial was still alive more than 20 years laterHow the immune systems of these women continued to recognize cancer cells long after the trialWhat CD27-positive immune cells are and why they matter, explained simplyWhy helper CD4 T cells may be just as important, or more important, than killer CD8 T cells when it comes to cancerWhat happened when researchers combined a CD27-boosting antibody with a cancer vaccine in miceWhat surprised the research team mostThe challenges of translating findings from mice to human trialsWhether cancer could someday be managed long-term by the immune systemHow generalizable this immune memory might be across different cancersWhat this research could mean for how we think about vaccines in a post-pandemic worldThe one key message the researcher hopes the public takes awayWhat's next in this line of researchThis episode offers a rare, hopeful (but scientifically grounded) look at how the immune system may be capable of remembering cancer for decades. Guest Bio: Dr. Zachary C. Hartman is an Associate Professor at Duke University in the Departments of Surgery, Pathology, and Integrative Immunobiology, where he also serves as Director of the Center for Applied Therapeutics and is a member of the Cellular and Molecular Biology and Genetics and Genomics programs. He earned his undergraduate degree from Northwestern University and completed his PhD at Duke University, followed by postdoctoral training in tumor immunology and breast oncology at Duke and the MD Anderson Cancer Center. In 2012, Dr. Hartman returned to Duke to establish a research program focused on tumor immunology and the development of cancer immunotherapies, including therapeutic vaccines, immune agonists, checkpoint inhibitors, antibody-based therapies, and strategies to stimulate anti-tumor immune responses. Work with me? Perhaps we are a good match. You can contact Dr. Eeks at bloomingwellness.com.Follow Eeks on Instagram here.Follow Public Health is WeirdOr Facebook here.Or X.OnSupport the show
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In this episode, Dr. Jun Ding joins us to explore how artificial intelligence and machine learning are reshaping biomedical research at the cellular level. Dr. Ding is an Assistant Professor in the Division of Respiratory Medicine at the Research Institute of the McGill University Health Centre and leads the Ding Lab at McGill University's Meakins-Christie Laboratories. Dr. Ding's research focuses on decoding cell dynamics across complex diseases by leveraging advanced single-cell technologies and computational biology. By developing machine-learning models such as probabilistic graphical models, Dr. Ding and his team aim to bridge massive omics datasets with actionable biological insight – paving the way for next-generation diagnostics and therapeutics… Hit play to discover: Why understanding cell dynamics is critical to tackling complex diseases like cancer. How single-cell and spatial omics technologies are revealing previously hidden biological heterogeneity. The role of machine learning in modeling disease progression and identifying new drug targets. To learn more about Dr. Ding and his work, visit The Ding Lab website!
In this Mol Bio Minutes mini-episode, Laurynas Alijošius shares how Rolling Circle Amplification (RCA) provides a reliable, high-yield approach for amplifying circular DNA prior to next-generation sequencing (NGS). This isothermal method avoids the need for thermal cycling and even bypasses the need for specific primers—making it ideal for challenging viral genomes, rare targets, or field samples.Powered by the strand-displacing phi29 DNA polymerase, RCA amplifies DNA with impressive sensitivity and minimal GC bias. Laurynas breaks down the steps of multiple displacement amplification (MDA), explains why exonuclease-resistant primers are important, and explores how engineered polymerases like EquiPhi29™ DNA Polymerase dramatically improve yield and reduce reaction times. RCA products can be cleaned up and debranched to support a range of downstream workflows, including nanopore sequencing and transcriptomics.From single-cell genomics to phage-based applications and in vitro expression systems, RCA is more than just a pre-NGS step; it's a versatile tool with broad utility. Whether you're stabilizing viral RNA or tackling ultra-low-input samples, RCA and whole genome amplification offer new flexibility for today's demanding sequencing workflows. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague. Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.
Vitamin B12 is essential for energy production, nervous system function, and overall metabolic health, but not all B12 forms deliver equal bioavailability or stability. In Episode #196 of the PricePlow Podcast, we welcome back HTBA (HealthTech BioActives) for a comprehensive deep dive into the science behind their MecobalActive methylcobalamin ingredient and the groundbreaking clinical study that validates its efficacy in athletes who are not deficient. Joining us are Teresa Pellicer, PhD, Pharmacologist and R&D Manager in Biotechnology at HTBA, and Bernardo Gonzaga, Global Division Manager for Functional Health Solutions. This conversation builds on Episode #188 with Edwin Gonzalez, where we explored practical applications of MecobalActive in functional foods. Today, we go deeper into the molecular mechanisms, clinical evidence, bioavailability data, and manufacturing innovations that make MecobalActive a next-generation B12 solution for supplements, functional foods, and beverages. Teresa’s expertise in pharmacology and molecular biology shines as she explains why methylcobalamin represents the biologically active form your body actually uses, while Bernardo provides industry context on applications, regulatory considerations, and market opportunities. Subscribe to the PricePlow Podcast on your favorite platform, and sign up for HTBA news alerts before we dive into the science. https://blog.priceplow.com/podcast/podcast/htba-mecobalactive-vitamin-b12-196 Video: The Science Behind MecobalActive Vitamin B12 https://www.youtube.com/watch?v=3v5NgW5jD-E Detailed Show Notes: Teresa Pellicer and Bernardo Gonzaga Discuss MecobalActive B12 (0:00) – Welcome and Introductions (2:00) – Teresa’s Background in Pharmacology and Molecular Biology (4:15) – Bernardo’s Industry Journey and Global Perspective (6:30) – HTBA Company History and Four Business Divisions (9:15) – Pharmaceutical-Grade Quality for Injectable B12 (11:00) – Sustainability Story: Upcycling Baby Oranges for Bioflavonoids (13:45) – ESG Commitment Beyond Environmental Impact (16:00) – Why Vitamin B12 Matters for Energy and Health (19:30) – The Four Main Forms of Vitamin B12 (22:45) – Why Cyanocobalamin Dominates Despite Conversion Requirements (26:15) – MecobalActive: Solving Methylcobalamin’s Stability Challenge (29:45) – The Clinical Study Design and Objectives (33:00) – Study Results: Superior Bioavailability and Faster Absorption (36:30) – Methylation Pathways and Homocysteine Metabolism (40:00) – Adenosylcobalamin and Mitochondrial Energy Production (43:45) – Populations at Risk for B12 Deficiency (47:15) – Symptoms and Consequences of B12 Deficiency (51:00) – Absorption Mechanisms: Intrinsic Factor Pathway (54:45) – Passive Diffusion and High-Dose Supplementation (58:15) – Manufacturing Challenges with Methylcobalamin Stability (1:01:30) – Applications in Functional Foods and Beverages (1:05:00) – Dosing Considerations and Safety Profile (1:08:30) – Combining B12 with Other B Vitamins and Nutrients (1:12:00) – Regulatory Landscape Across Global Markets (1:15:45) –… Read more on the PricePlow Blog
In this episode, we are joined by Dr. Kristy McAndrew from Mississippi State University. Dr. McAndrew will walk us through the ins and outs of Brown spot needle blight, a fungal disease that infects pine needles, leading to premature needle loss, stunted growth, and long-term stress that increases a tree's vulnerability to other pests and pathogens, and provide an update on Emerald Ash Borer presence in the region. Dr. McAndrew is a forest health specialist at Mississippi State University in the Forestry Department. Kristy has a Bachelor of Science in Forestry and a Bachelor of Science in Fisheries & Wildlife, both from the University of Missouri in Columbia, MO, and also completed a Master's and PhD at Mississippi State University in the Department of Biochemistry, Molecular Biology, Entomology, and Plant Pathology. For more on brown spot needle blight, see this recent article and publication from the Arkansas Division of Agriculture. www.uaex.uada.edu/media-resources/news/2025/august/08-18-2025-ark-UAM-needle-blight.aspx If you have questions, feel free to contact us at timberuniversity@gmail.com
The world is entering a new era of conflict: more violent, more fragmented, and with more civilians caught in the crossfire than at any time since World War II. But the consequences of war may extend far beyond the battlefield. Rana Dajani, Jordanian molecular biologist and long-time member of the Tällberg network, is part of a research team uncovering how traumatic violence might alter gene expression and affect not only survivors but also their children and grandchildren. In this episode, she explains the emerging science behind intergenerational trauma and explores what these findings could mean for societies living through—and after—conflict.
Applyo Jena is building a freeze-dried future, one bead at a time. In this episode, Dr. Hanno Hermann and Dr. Thanh Tu Hellmich-Duong walk us through how their lyo-bead technology emerged from the challenges of field-based HIV diagnostics and evolved into a flexible platform that stabilizes everything from enzymes to magnetic nanoparticles, without the need for refrigeration.From diagnostics research to therapeutics, this lyophilization platform is solving key pain points in reagent formulation, shipping, and field use. Hanno and Thanh Tu explain how lyo-beads offer precise, single-use reagent doses with near-instantaneous rehydration, minimal batch-to-batch variability, and extended ambient temperature stability. Whether it's for isothermal RT-LAMP, next-gen sequencing prep, or phage-based application, Applyo's platform unlocks new formats, simplifies logistics, and lowers the environmental burden of molecular workflows.With new hires, new markets, and new product lines on the horizon, Applyo Jena is poised for a decade of growth and maybe even a hand in reshaping the way freeze-dried pharmaceuticals are developed and delivered. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague. Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.
Matters Microbial #117: Cancer Virus Hunters and Molecular Biology December 8, 2025 Today Dr. Gregory Morgan, Professor in the School of Humanities, Arts, and Social Sciences at Stevens Institute of Technology, joins the #QualityQuorum to discuss how cancer causing viruses advanced molecular biology as described in his recent book Cancer Virus Hunters. Host: Mark O. Martin Guest: Gregory Morgan Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a link to Dr. Morgan's book on the topic discussed today. A lovely interview with Dr. Morgan about his book. A great history of molecular biology, "Eighth Day of Creation" by Horace Freeland Judson. The History and Philosophy of Science program at the University of Pittsburgh. An overview of the Rous Sarcoma Virus. A biography of Dr. Peyton Rous. A video describing how RSV causes cancer by "stealing" normal genes. How some viruses may contribute to the development of cancer. Here is another video on that topic. The field of tumor virology. A really wonderful video on the genetic origin for cancer. An overview of oncogenes and protooncogenes. A video exploring how proto-oncogenes become oncogenes, and can contribute to the development of cancer. The concept of "contagious cancer" that is rare but exists. The story of papilloma viruses and "jackalopes." The history of Cold Spring Harbor Laboratory. An overview of retroviruses. Retroviruses and FeLV. Blue chicken eggs and ancient retroviruses. A summary for novice #Micronauts. Mammalian (including human) placenta and ancient retroviruses. Nixon's "War on Cancer." An overview of the src gene. An overview of the ras gene. An overview of the p53 gene. A video explainer of the enzyme reverse transcriptase. A biography of Howard Temin. A biography of David Baltimore. The story of Human Papillovirus (HPV) and cancer. Dr. Morgan's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
Maria Barna is an authority on ribosomes – “life's most ancient and spectacular molecular machines.” Ribosomes make proteins in the body. There can be a thousand different types of ribosomes in a single cell, she says, each with a specific job to do. But sometimes things go awry and ribosomes get “hijacked,” leading to disease. Barna studies these “diabolical” variations to find new therapies to treat diseases ranging from cancer and COVID to Parkinson's. When diseases hit, it's all about the ribosomes, Barna tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Maria BarnaConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Maria Barna, a professor of genetics at Stanford University.(00:04:21) Origins of Ribosome ResearchMaria explains why ribosomes became the focus of her work.(00:06:14) Ribosome Function and ScaleRibosomes' functions and the energy required for their production.(00:08:28) Ribosomes as MachinesHow ribosomes influence which proteins are produced and when.(00:09:48) Ribosome RegulationThe regulatory layers within ribosomes and their possible variants.(00:14:35) Ribosomes and DiseaseHow ribosomal dysfunction is linked to a wide range of diseases.(00:18:16) Ribosome Mutations and DevelopmentCongenital disorders that can be attributed to specific ribosomal mutations.(00:20:44) RNA vs. Protein OutputWhy RNA measurements alone do not accurately predict protein levels.(00:24:16) Designing Ribosomes for TherapyThe potential of using engineered ribosomes for target therapies.(00:26:16) Small-Molecule Ribosome ModulatorsScreening compounds that may enhance ribosome activity for treatments.(00:28:39) Future Ribosome ProfilingIsolating individual ribosomes to understand their specific roles.(00:30:35) Future In a MinuteRapid-fire Q&A: scientific progress, community, and alternative career interest.(00:34:01) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Marta Paterlini"La pelle che pensa"Il tatto come linguaggio universale, tra filosofia, neuroscienze e tabù sociali.Codice Edizioniwww.codiceedizioni.itSottovalutato e dato per scontato, cos'è successo al tatto, l'atto più semplice e antico dell'umanità? Il tatto nasconde un mondo: è un linguaggio universale, un dialogo tra cervello e pelle, un atto di cura e una forma di resistenza in un'epoca in cui i corpi si allontanano. Centrale nei miti dell'Odissea e indagato dalla filosofia fin da Aristotele, il tatto è finalmente studiato dalle neuroscienze, che ne mostrano l'essenza: dalle carezze che alleviano il dolore nelle cure palliative alle fibre nervose che trasformano un massaggio in benessere; dalla fragilità di chi si chiude al contatto alla fame di pelle che genera disagio mentale. Nella società il tatto riflette visioni diverse del corpo, dell'identità e della cultura: la pelle sintetica della robotica, il tocco sociale, l'evoluzione dei saluti, le manipolazioni mediche, le politiche no-touch nelle scuole, fino alle ricerche sui canali Piezo del premio Nobel Ardem Patapoutian e alle fibre C-tattili del tocco affettivo. Sono questi i tasselli del mosaico che la neuroscienziata e divulgatrice Marta Paterlini ricompone in La pelle che pensa, mostrando come il tatto sia oggi sospeso tra tabù e necessità, paura del contatto e disperato bisogno di connessione. Perché toccare è curare, parlare, esistere.«In un mondo sempre più digitale, dove le relazioni spesso si sviluppano attraverso uno schermo, la pelle ci ricorda la magia del contatto diretto. Ogni abbraccio, ogni carezza, ogni stretta di mano è un ponte che ci avvicina, superando barriere culturali e linguistiche. Il tatto è uno dei primi canali attraverso cui esploriamo la realtà e instaura connessioni profonde tra gli individui. Ogni abbraccio sembra diverso perché tutti quelli che abbracciamo occupano spazio nel mondo in un modo diverso». Marta PaterliniMarta PaterliniNeurobiologa e giornalista scientifica freelance. Ha lavorato presso il Laboratory of Molecular Biology di Cambridge, in Inghilterra, e alla Rockefeller University di New York. Attualmente è senior scientist presso il Karolinska Institutet di Stoccolma, dove vive. Collabora con “Science”, “Nature” e “The Lancet”.Diventa un supporter di questo podcast: https://www.spreaker.com/podcast/il-posto-delle-parole--1487855/support.IL POSTO DELLE PAROLEascoltare fa pensarehttps://ilpostodelleparole.it/
With Marie-Noelle Giraud, Faculty of Science and Medicine, Fribourg - Switzerland and Carolina Balbi, Research Centre for Molecular Biology, University of Zurich - Switzerland. Link to European Heart Journal paper Link to European Heart Journal editorial
Today Jeremy is joined by Susan Morrow, PhD, who obtained her Doctor of Philosophy in Molecular Biology and Biochemistry from Louisiana State University Health Sciences Center. Susan describes her unique childhood growing up in a funeral parlor, her educational journey as well as moral conflicts she experienced as a professional scientist, and her ultimate decision to devote herself full time to raising her family.
Lauren, a native of Madison, WI, graduated with a B.S. in Molecular Biology and Spanish from the University of Wisconsin–Madison. She then earned her M.D. at Stanford University, where she was awarded a Howard Hughes Medical Institute (HHMI) research scholarship to study osteosarcoma at the National Cancer Institute (NCI) in Washington, D.C. She completed her internship at Santa Clara Valley Medical Center in San Jose, CA, followed by a residency in radiation oncology at Memorial Sloan-Kettering Cancer Center in New York City. After residency, Lauren joined the faculty of the University of Wisconsin Carbone Cancer Center, where she focused on thoracic radiation oncology and helped develop a spine stereotactic radiation program. In 2014, she transitioned to The Permanente Medical Group, serving as a radiation oncologist at Kaiser Permanente in Northern California and later as regional lymphoma subspecialty lead until her departure in 2023. She then joined the University of Colorado Department of Radiation Oncology, where she served on the faculty until June 2025.Lauren is currently pursuing additional training in palliative care while continuing to provide locum tenens radiation oncology coverage across Colorado and California. She is passionate about delivering evidence-based, patient-centered care—a commitment that is deeply personal and influenced by her experiences watching both of her parents undergo cancer treatment.The desire to be closer to friends and family—and a shared love of the outdoors—brought Lauren and her family to Colorado. She resides in Morrison with her husband, Anthony, a native of England who runs a consulting practice specializing in cell and gene therapies. Together they enjoy the lively company of their two children, Anna and Charlie, along with an ever-growing menagerie of pets. As a family, they love hiking, gardening, sharing tea and biscuits, and catching up on sleep whenever possible.**********************************************************Judy Carlson is the CEO and Founder of the Judy Carlson Financial Group, where she helps couples create personalized, coordinated financial plans that support the life they want to live – now and in the future.As an Independent Fiduciary and Comprehensive Financial Planner, Judy specializes in retirement income and wealth decumulation strategies. She is a CPA, Investment Advisor Representative, licensed in life and health insurance, and certified in long-term care planning.Judy's mission is to help guide clients with clarity and care, building financial plans that focus on real planning built around real lives.Learn More: https://judycarlson.com/The Inspired Impact Podcasthttps://businessinnovatorsradio.com/the-inspired-impact-podcast/Source: https://businessinnovatorsradio.com/the-inspired-impact-podcast-with-judy-carlson-interview-with-lauren-shapiro-md-radiation-oncologist
In this Mol Bio Minutes episode, Thermo Fisher Scientific's Monika Jazdauskaitė dives into the versatile world of Recombinase Polymerase Amplification (RPA). Unlike PCR, RPA operates at a constant, low temperature (around 37–42°C), enabling fast, equipment-light workflows that are ideal for field diagnostics and decentralized labs. Monika explains how the method works and why RPA is emerging as a go-to technique for both DNA and RNA target detection.She highlights RPA's specificity, sensitivity, and robustness against common inhibitors like ethanol and heparin, critical for applications like respiratory pathogen detection or low-quality sample inputs. Plus, she shares how RPA's gentle conditions and lyophilization compatibility make it a strong candidate for stabilizing next-generation sequencing (NGS) libraries, especially those with high GC content.Whether you're looking to simplify pathogen detection or streamline your sequencing prep, RPA offers a compelling alternative to traditional amplification. And with ready-to-use kits like the Invitrogen™ Lyo-ready RPA Kit, Thermo Fisher is helping researchers bring speed and stability to molecular workflows, all with no thermal cycler required. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague. Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.
Send us a textIn this episode of Unwritten Beauty Talks, host Katarina Forster sits down with Dr. Dave Stachura and Tiffany Underwood from Factor Five Skincare to explore the science behind growth factors, stem cells, exosomes, and clean beauty.They discuss Factor Five's mission to create effective, clean skincare products without fillers or unnecessary additives, the science behind their formulations, and how their products address a wide range of skin concerns. The conversation also delves into how skincare treatments promote healing, collagen production, and client confidence, while highlighting the differences between stem cells, growth factors, and exosomes.Factor Five Skincare focuses on growth factors and stem cells to deliver effective skincare solutions.Their mission is to provide clean, additive-free products without compromising results.Understanding the differences between stem cells, growth factors, and exosomes is key for informed skincare decisions.Skincare treatments often involve controlled disruptions to promote healing, collagen production, and skin renewal.Factor Five products are designed for a wide range of skin types and concerns, including sensitive skin.Their eye and lash cream is highly effective and safe for daily use.Retinol can be safely included in skincare for sensitive skin when formulated correctly.Exosomes need to be stabilized for effective use in topical skincare products.Dr. Dave Stachura – Chief Operations Officer and Chief Scientific Officer at Factor Five Skincare and SpecBio, Dr. Stachura leads the science behind all Factor Five formulations. He holds a BSc in Molecular Biology from Lehigh University and a PhD in Cellular and Molecular Biology from the University of Pennsylvania, followed by postdoctoral training at UC San Diego. His career focuses on genetic control of adult stem cell biology using hematopoietic stem cells (HSCs) and adipose-derived mesenchymal stem cells (ADMSCs). Dr. Stachura has several patents, published over 40 peer-reviewed articles, contributed two book chapters, and edited an immunology textbook. He continues research in stem cells, immunology, exosomes, skincare, and wound healing and founded Philanthropic Pharma, a nonprofit pharmaceutical company aimed at discovering new treatments for human diseases.Tiffany Underwood – Director of Education at Factor Five Skincare, Tiffany works closely with professional partners and brings a strong clinical perspective to the team. A licensed esthetician and founder of SkinCo, she blends biology, product formulation, and advanced esthetics to deliver results-driven treatments while empowering professionals to stay connected to their “why.” Inspired by her journey with cancer.
The Smart 7 is an award winning daily podcast, in association with METRO that gives you everything you need to know in 7 minutes, at 7am, 7 days a week...With over 19 million downloads and consistently charting, including as No. 1 News Podcast on Spotify, we're a trusted source for people every day and the Sunday 7 won a Gold Award as “Best Conversation Starter” in the International Signal Podcast Awards If you're enjoying it, please follow, share, or even post a review, it all helps...Today's episode includes the following guests:David Liu - Professor of the Natural Sciences at Harvard University, specialising in Molecular Biology and Organic ChemistrySteven Pinker - The Johnstone Family Professor of Psychology at Harvard University, Mark Zuckerberg = Founder and CEO of Facebook.Frances Balkwill = Professor of Cancer Biology at Queen Mary College Hospital Doctor Alexandra Solomon - Clinical psychologist, and Associate Professor at Northwestern University Dr Ed Robinson - Specialist in Cosmetic Aesthetics, and Associate member of the British College of Aesthetic Medicine Stephen Childs - Lab Technician and Analyst at Sunderland UniversityKerry Nicol - External Affairs Manager for the Chartered Trading Standards Institute Joe Morse = Associate Test Pilot for US Company Pivotal Ken Clarkin - CEO of Pivotal Dr Randy Bateman - Professor of Neurology at Washington University Dr Christos Pliatsikas -Associate Professor at the School of Psychology and Clinical Sciences at the University of Reading Paulina Arce - Veterinary expert, specialising in the Humboldt Penguin Guillermo Cubillos - Marine Biologist at Chile's National ZooContact us over @TheSmart7pod or visit www.thesmart7.com or find out more at www.metro.co.uk Presented by Ciara Revins, written by Liam Thompson, researched by Lucie Lewis and produced by Daft Doris. Hosted on Acast. See acast.com/privacy for more information.
Biochemist Lingyin Li survived breast cancer at just 30 and now works to harness the human immune system to fight cancers that have long evaded treatment. T cells, she says, are powerful cancer killers, but they can be oblivious. She and her lab colleagues have discovered a masking enzyme that squelches the immune system's “danger signals” and are now developing drugs to block that enzyme. She likens her work to an arms race between cancer and immunotherapy. “The cancers are not getting smarter, but we are,” Li tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Lingyin LiConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Lingyin Li, a professor of biochemistry at Stanford University.(00:03:38) Research MotivationLingyin explains how her breast cancer diagnosis inspired her research.(00:04:31) How T-Cells WorkT-cell mechanisms and why they struggle to reach solid tumors.(00:05:38) Immune System OverviewInnate and adaptive immunity and how mutations make cancer recognizable.(00:07:28) Awakening the Immune SystemEfforts to stimulate innate immune cells to detect and expose tumors.(00:10:54) The Cancer SignalDiscovery of cancer-derived DNA signals that alert the immune system.(00:13:01) Cancer's Evasion MechanismHow tumors destroy immune signals to hide from detection.(00:14:26) ENPP1 EnzymeIdentification of ENPP1 as the enzyme enabling immune evasion.(00:15:22) Balancing Immunity and SafetyRole of ENPP1 in autoimmunity and the challenge of targeting it safely.(00:19:30) ENPP1 InhibitorsDevelopment of molecules to block ENPP1 and enhance immune signaling.(00:24:55) Preclinical FindingsThe promising results against aggressive solid tumors in animal studies(00:28:05) From Lab to ClinicThe progress toward FDA approval and preparation for human testing.(00:31:04) Future In a MinuteRapid-fire Q&A: innovation, collaboration, and the outlook for cancer treatment.(00:33:14) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Looking for more information on this topic? Check out the Shock brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts. It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks. After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.
In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, dives deep into estrone, one of the three key estrogens, and explains why understanding it is crucial for women's health. Learn about: The differences between estradiol, estriol, and estrone How estrone levels shift during perimenopause and menopause Why oral estrogen can dramatically increase estrone The impact of lifestyle factors like diet, body fat, stress, alcohol, and sedentary behavior on estrogen balance Practical tips to support healthy estrogen metabolism naturally Dr. McCarthy breaks down complex biochemistry in a clear, actionable way so you can take charge of your hormonal health. Citations: 1. Bulun, Serdar E., et al. “Aromatase and Estrogen Biosynthesis in Adipose Tissue.” Endocrine Reviews, vol. 23, no. 3, 2002, pp. 305–342. 2. Labrie, Fernand, et al. “Importance of the Intracrinology of Estrogen Synthesis in Peripheral Tissues in Postmenopausal Women.” Journal of Steroid Biochemistry and Molecular Biology, vol. 118, nos. 4–5, 2010, pp. 273–279. 3. Sasano, Hironobu, and Toshihiko Harada. “Differential Expression of Aromatase and 17β-Hydroxysteroid Dehydrogenase Isoenzymes in Human Tissues.” Journal of Steroid Biochemistry and Molecular Biology, vol. 86, no. 3–5, 2003, pp. 327–333. 4. Yager, James D., and Nancy E. Davidson. “Estrogen Carcinogenesis in Breast Cancer.” New England Journal of Medicine, vol. 354, no. 3, 2006, pp. 270–282. 5. Cavalieri, Ercole L., and Eleanor G. Rogan. “Depurinating Estrogen-DNA Adducts, Mechanisms of Formation, and Prevention.” Clinical Cancer Research, vol. 16, no. 3, 2010, pp. 596–602. 6. Suba, Zsuzsanna. “Circulating Estrogens and Estrogen Metabolism in Obese Women.” Journal of Clinical Endocrinology and Metabolism, vol. 98, no. 11, 2013, pp. 4336–4344. 7. Simpson, Evan R., and Konstanze C. Pike. “Aromatase Expression in Adipose Tissue: Relationship to Obesity and Insulin Resistance.” Endocrinology, vol. 156, no. 9, 2015, pp. 3422–3435. 8. Key, Timothy J., et al. “Circulating Sex Hormones and Breast Cancer Risk Factors in Postmenopausal Women: Reanalysis of 13 Studies.” British Journal of Cancer, vol. 105, no. 5, 2011, pp. 709–722. 9. Stanczyk, Frank Z., et al. “Oral, Transdermal and Injectable Hormone Therapy: Pharmacokinetics and Effects on Estrone/Estradiol Ratios.” Menopause, vol. 24, no. 9, 2017, pp. 1080–1090. 10. Santen, Richard J., et al. “Estrogen Bioidentical Hormone Therapy: Route of Administration and Risk.” Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 7, 2020, pp. 2062–2074. 11. Zeleniuch-Jacquotte, Anne, et al. “Postmenopausal Levels of Estrone, Estradiol, and Estrone Sulfate and Breast Cancer Risk.” Cancer Epidemiology, Biomarkers & Prevention, vol. 23, no. 8, 2014, pp. 1531–1539. 12. Dall, Gabriella V., and Christine L. Clarke. “Local Estrogen Biosynthesis and Signaling in Breast Cancer Progression.” Steroids, vol. 78, no. 7, 2013, pp. 639–646. 13. Heald, Anthony H., et al. “Relationships Between Serum Estrone, Insulin Resistance, and Adiposity in Postmenopausal Women.” Clinical Endocrinology, vol. 67, no. 3, 2007, pp. 340–345. 14. Kuiper, George G. J. M., et al. “Estrogen Receptor β Selectivity of Estriol and Implications for Tissue-Specific Effects.” PNAS, vol. 94, no. 17, 1997, pp. 9105–9110. 15. Michnovicz, Joseph J., et al. “Dietary Indoles and Estrogen Metabolism: Effects of Cruciferous Vegetable Intake.” Journal of Nutrition, vol. 134, no. 12, 2004, pp. 3479S– Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.
In this episode, we are joined by Olga Goldberger, founder of IOKA Skin + Science. Olga holds a Master's degree in Molecular Biology, and she strived to create a skincare system that applied science to active botanical ingredients that would penetrate the skin and support skin health on the cellular level.Topics: 1. Anatomy and Function of the Skin Barrier- Structure of the epidermis, highlighting the Stratum Corneum.- Role of corneocytes and intercellular lipids in barrier integrity. 2. Emulsifiers and Surfactants- Mechanisms of action.- Interaction with skin lipids and proteins.- Classification.- Transepidermal water loss (TEWL).- Wash-Out Effect. 3. Phospholipids in Skincare Formulation 4. Parabens- Endocrine implications. 5. Fragrance components 6. Synthetic colorants 7. Exfoliating agents- Chemical exfoliants and fruit-derived enzymes. 8. Lifestyle and Environmental Influences- External and internal contributors to oxidativestress. 9. Dermal Fibroblasts- Collagen and elastin. 10. NAD+ and precursors.11. Antioxidants including pterostilbene.12. Bakuchiol13. Topical acetyl hexapeptide-8 and copper tripeptide-1.14. IOKA Skin + Science.Explore all IOKA Skin + Science products here. Thanks for tuning in!Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellnessVisit synthesisofwellness.com
Been wondering what to believe about acetaminophen? It's found in many over-the-counter products, not just Tylenol. Guest Dr. Christina Parks earned a double major in Biochemistry and Molecular Biology and Chemistry Honors and a Ph.D. in Cellular and Molecular Biology. As an educator, she helps us all understand the science so we can make informed decisions.Reference Linkshttps://informedchoicewa.substack.com/https://www.vi-ta.org/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this powerful episode of The Birth Lounge Podcast, HeHe sits down with infectious disease scientist, Ellie to pull back the curtain on what's really behind vaccines, immunity, and medical ethics. After years working in big pharma, Ellie began questioning what she saw from the inside, and now she's here to help parents unpack the complex, often confusing world of vaccine science through an evidence-based, transparent lens. Together, HeHe and Ellie dive into everything from the ingredients found in common vaccines (and why they're there!) to the differences between live and attenuated viruses. They also explore the ethics of vaccine research, including the use of fetal cell lines, vaccinated vs. unvaccinated clinical trials, and how informed consent fits into modern medicine. This conversation isn't about fear, it's about facts. It's about asking better questions, understanding your options, and feeling confident in the choices you make for your family's health. Ellie brings scientific clarity, a refreshing dose of honesty, and a deep respect for parental autonomy to this nuanced conversation. If you've ever wanted a clearer understanding of vaccines and the ethics behind them, this episode is a must-listen. 03:27 Announcing the New Course: Pushing Out Your Big Ass Baby 05:34 Vaccine Exploration Series Finale 06:19 Ingredients in Vaccines: What You Need to Know 07:35 Interview with Infectious Disease Scientist Ellie 12:11 Ellie's Journey from Big Pharma to Vaccine Skepticism 40:44 Ethical and Scientific Concerns in Vaccine Development 01:02:33 Pharmaceutical Interactions and Clinical Trials 01:04:28 Autonomy and Vaccine Mandates 01:05:17 Herd Immunity and Vaccine Efficacy 01:06:38 Transparency and Trust in Healthcare 01:15:49 Ethics of Vaccine Studies 01:19:12 Challenges in Scientific Research 01:23:55 Vaccine Ingredients and Allergies 01:26:42 Live vs. Attenuated Vaccines 01:29:49 Shingles and Vaccine History 01:33:43 Scientific Communication and Public Trust 01:43:08 Final Thoughts and Resources Guest Bio: Ellie is an infectious disease scientist with a powerful personal story and a passion for making science accessible. With a B.S. in Cellular and Molecular Biology and an M.S. in Infectious Diseases and Microbiology, Ellie has spent years on the front lines of science—from developing vaccines for potential bioweapons during her graduate research to working in assay development and infectious disease research within the pharmaceutical industry. Four years ago, she made the bold decision to step away from pharma and pursue a path that blends science, personal experience, and public education. Ellie was born with a left radial clubbed hand, congenital heart issues, and other challenges caused by a pharmaceutical product—an experience that has shaped her unique perspective on medicine. After undergoing countless surgeries, she deeply understands the life-saving value of western medicine, while also recognizing that alternatives can have a place in care. Ellie now dedicates herself to helping people understand complex scientific topics so they can make empowered, informed health decisions. She believes that her journey—both scientific and deeply personal—is no accident. Through all the challenges she has faced, she's seen the hand of Jesus guiding her path and believes God has kept her alive for a greater purpose. INSTAGRAM: Connect with HeHe on IG Connect with Ellie on IG BIRTH EDUCATION: Join The Birth Lounge here for judgment-free childbirth education that prepares you for an informed birth and how to confidently navigate hospital policy to have a trauma-free labor experience! Download The Birth Lounge App for birth & postpartum prep delivered straight to your phone! RESOURCES MENTIONED: https://cogforlife.org/ https://www.cellosaurus.org/ You can search a variety of ways in the site, but one is 'browse by group' and click 'Vaccine production cell lines'
Dr. Elaine Guevara is a Lecturer in Evolutionary Anthropology at Duke University. She teaches biology and conducts research on the evolution of primates using molecular approaches. One area of Elaine's research examines the evolution of brain aging and how brain aging differs between humans and our primate relatives, including certain species of lemurs. When it's time to relax, Elaine loves to read. She is particularly fond of Golden Age mysteries, similar modern mystery authors, investigative journalism, history, and social science content. In addition to reading, Elaine enjoys biking, being outdoors, exploring the mountains, observing wildlife, playing games, sipping wine, and hanging out with friends. She received her BA in biological anthropology from the University of California, Santa Cruz, and her MA in biological anthropology from Hunter College. During her master's program, Elaine also worked at the American Museum of Natural History as an Archives Assistant and subsequently a Database Assistant. She then received her PhD from Yale University. Afterwards, Elaine conducted postdoctoral research at The George Washington University. She joined the faculty at Duke in 2021, and she also served briefly as a faculty member at the University of North Carolina Wilmington. In our interview, Elaine shares more about her life and science.
mRNA vaccines are not supposed to contain DNA. But Dr. Jessica Rose says a new study tested “32 vials of Pfizer and Moderna COVID products that included 16 unique lots… We did not only find DNA, we found it in ALL lots tested and most importantly, the DNA levels were all above pre-designated EMA thresholds of 10 ng/dose.” “We measured the amount of DNA in the vials using 2 methods… (qPCR and fluorometry),” she continues. “It was submitted as evidence on the congressional record by the honorable Senator Ron Johnson.” JP Sears is a comedian, author, and YouTuber known for his satirical take on politics, fitness, and faith. He hosts Awaken with JP on Rumble and YouTube. Follow at https://x.com/AwakenWithJP Dr. Jessica Rose is a Canadian researcher with a Bachelor's in Applied Mathematics and a Master's in Immunology from Memorial University of Newfoundland. She holds a PhD in Computational Biology from Bar Ilan University and completed postdoctoral research in Molecular Biology and Biochemistry. Find her at https://jessicasuniverse.com and follow at https://x.com/JesslovesMJK 「 SUPPORT OUR SPONSORS 」 Find out more about the brands that make this show possible and get special discounts on Dr. Drew's favorite products at https://drdrew.com/sponsors • FATTY15 – The future of essential fatty acids is here! Strengthen your cells against age-related breakdown with Fatty15. Get 15% off a 90-day Starter Kit Subscription at https://drdrew.com/fatty15 • PALEOVALLEY - "Paleovalley has a wide variety of extraordinary products that are both healthful and delicious,” says Dr. Drew. "I am a huge fan of this brand and know you'll love it too!” Get 15% off your first order at https://drdrew.com/paleovalley • VSHREDMD – Formulated by Dr. Drew: The Science of Cellular Health + World-Class Training Programs, Premium Content, and 1-1 Training with Certified V Shred Coaches! More at https://drdrew.com/vshredmd • THE WELLNESS COMPANY - Counteract harmful spike proteins with TWC's Signature Series Spike Support Formula containing nattokinase and selenium. Learn more about TWC's supplements at https://twc.health/drew 「 MEDICAL NOTE 」 Portions of this program may examine countervailing views on important medical issues. Always consult your physician before making any decisions about your health. 「 ABOUT THE SHOW 」 Ask Dr. Drew is produced by Kaleb Nation (https://kalebnation.com) and Susan Pinsky (https://twitter.com/firstladyoflove). This show is for entertainment and/or informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment. Learn more about your ad choices. Visit megaphone.fm/adchoices
Cultural humility is a lifelong practice of self-reflection, openness, and respect for the diverse backgrounds of the families we serve. Unlike cultural competence, which can imply mastering knowledge about “other cultures,” cultural humility emphasizes curiosity, listening, and shared decision-making. In pediatrics, this is especially important because care involves both the child and the family, whose cultural values strongly shape health beliefs and practices.Today's discussion is an opportunity to reflect together: how do we approach cultural humility in pediatrics, and what steps can we take to deepen it in our daily practice?Dr. Ana Aguilar, DO is originally from Loveland, OH. She went to Transylvania University where she did not major in Blood-Sucking and Shadow-Walking, but instead earned a dual degree in Molecular Biology and Anthropology. She attended Ohio University Heritage College of Osteopathic Medicine and is a very recent Loyola graduate, now completing a chief year with her best friend and co-chief, Dr. Sana Moqeet, MD. In her spare time, Ana enjoys reading, solving puzzles, writing and denying vampire allegations.Episode produced by: Deborah ChenEpisode recording date: 09/11/2025www.medicuspodcast.com | medicuspodcast@gmail.com | Donate: http://bit.ly/MedicusDonate
On this episode of ID the Future selected out of our vault, host Eric Metaxas begins a conversation with biologist and professor Dr. Douglas Axe on The Eric Metaxas show. Axe is the Maxwell Professor of Molecular Biology at Biola University, the founding Director of Biologic Institute, the founding Editor of BIO-Complexity, and the author of Undeniable: How Biology Confirms Our Intuition That Life is Designed. In Part 1, Dr. Axe shares how he lost his research position in Cambridge during a season of political controversy over Darwinian evolution in the UK. He also shares what he learned from his experiments in protein evolution that cast doubt on the neo-Darwinian explanation for life. This is Part 1 of a two-part conversation. Source
In this episode, Dr. Bill Andrews joins Dr. Buck Joffrey to discuss the critical role of telomeres and telomerase in aging and cellular health. He explains how telomeres shorten with each cell division, leading to aging and cellular senescence. Dr. Andrews emphasizes the importance of inducing telomerase to potentially reverse aging and shares insights from his research on telomerase inducers. He also addresses the challenges in longevity research, the relationship between telomeres and the hallmarks of aging, and the potential of gene therapy. The conversation concludes with a discussion on lifestyle factors that can influence aging and the future of aging research. Learn more about Dr. Bill Andrews: https://sierrasci.com/dr-bill-andrews/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/
Looking for more information on this topic? Check out the Physiology of the Renal Tubular System brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts. It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks. After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.
Dr. Jeff Gross — Board-certified neurological surgeon, biochemist, biohacker, founder of Celebrate Regenerative Medicine, and longevity/biohacking consultant based in Las Vegas & Southern California. Medical & Health Longevity Background: Dr. Gross trained at UC Berkeley (Biochemistry & Molecular Biology), George Washington University School of Medicine, UC Irvine (Neurosurgery), and UNM (Spinal Biomechanics). He has decades of frontline experience in spine surgery, sports injuries, regenerative medicine, and now consults on biohacking and longevity. Biohacking & Longevity: Biohacking is essentially circles back to ancient wellness wisdom (eat well, sleep, exercise)—but enhanced by modern science (measuring phytonutrients, leveraging tech like red light, hyperbaric therapy, protein timing, etc). Emphasizes that “prevention” is still the number one defense against the four top causes of death in Western countries; early proactive screening and lifestyle habits remain critical. There is increasing crossover between “traditional medicine” and “naturopathic”/“functional” approaches—Dr. Gross sees this convergence as positive and overdue, but notes resistance still exists in mainstream medicine. Emerging Business Opportunities in the Wellness Space: IV centers, cryotherapy, and retail biohacking clinics (hyperbaric O2, red light therapy, peptides, weight loss clinics, etc.) are booming, especially in health-conscious cities. Low-barrier options: health coaching, nutrition consulting, affiliate/online influencer businesses—Dr. Gross notes people he knows personally earning seven figures as wellness affiliates. Innovations: Short-form EMS (electro-muscular stimulation) workouts, “blood flow restriction” exercise systems, and more. Cancer screening clinics: Now possible with advanced genomics and blood-testing—these are in demand but not widely available through traditional doctors/insurance, opening more avenues for direct-to-consumer providers. Supplementation & Biohacking Basics: “Non-negotiables” for almost everyone: Vitamin D3 (& often K2): Most people are deficient; optimal blood levels promote longevity, reduce inflammation, and lower all-cause mortality. Magnesium: Especially at night for recovery and cellular repair. Creatine: Improves muscle mass, heart health, and brain health; well correlated with longevity. Probiotics: Modern lifestyles make gut health challenging—good probiotic support is important. Nicotine: Can be a cognitive enhancer in low doses and proper delivery (gum/patch, NOT smoking)—but is highly addictive. Other Business/Money Ideas: Successful affiliate and influencer businesses for those passionate about health and wellness. Emphasizes supplement sales (with high trust and real value), personalized coaching, and education are evergreen opportunities. Industry Critique: Criticizes health insurance as a “legal mafia,” noting it often adds cost and hassle while limiting real preventive care. Encourages listeners to be their “own best advocate” for health—don't rely only on five-minute mainstream doctor visits. Connect with Dr. Jeff Gross: https://recellebrate.com/
In 2018, a peer-reviewed article published in Progress in Biophysics and Molecular Biology suggested the theory that octopuses could have extraterrestrial origins. As in, they're not regular Earthlings. The 33 scientists who authored the paper say, the octopus could have arrived on Earth, in some form, on board a celestial body – like an asteroid. Most of the scientific community disagreed. Experts said octopuses are alien-like, but there are clues to suggest they experienced a normal, Earth-bound evolution. However…they might hold clues about what alien behavior would look like. Today, we're joined by researcher Dominic Sivitilli, who tells us what studying octopus cognition can teach us about alien intelligence. Keep up with us on Instagram @theconspiracypod! Learn more about your ad choices. Visit podcastchoices.com/adchoices