Podcasts about mervyn singer

In a previous episode, Dr. Sergio Zanotti explored the importance of challenging dogma, particularly when the supporting evidence is weak or absent. Today, he continues that discussion by examining critical care practices that persist despite a lack of strong scientific validation. He's joined by Dr. Mervyn Singer, an internationally recognized leader in critical care medicine. Dr. Singer is a professor of intensive care medicine at University College London and a distinguished clinician, researcher, and educator. Through his research, publications, and dynamic presentations, he has inspired Dr. Zanotti — and countless intensivists worldwide — to think critically, challenge conventions, and push the boundaries of our field. Additional resources: Challenging management dogma where evidence is non-existent, weak, or outdated: part II. DA Hofmaennner and M. Singer. Intensive Care Med2024: https://pubmed.ncbi.nlm.nih.go Challenging management dogma where evidence is non-existent, weak, or outdated. DA Hofmaennner and M. Singer. Intensive Care Med 2022: https://pubmed.ncbi.nlm.nih.gov/35303116/ Biomarker-Guided Antibiotic Duration for Hospitalized Patients with Suspected Sepsis. The ADAPT-Sepsis Randomized Clinical Trial. JAMA 2025: https://pubmed.ncbi.nlm.nih.gov/39652885/ Hyperglycemic Crises in Adults with Diabetes: A Consensus Report. Diabetes Care 2024: https://pubmed.ncbi.nlm.nih.gov/38907161/ Books and music mentioned in this episode. Influenza: The Hundred-Year Hunt to Cure the 1918 Spanish Flu Pandemic. By. Jeremy Brown: https://amzn.to/3Ftb0mO Beethoven: 9 Symphonies / Karajan 1963: https://amzn.to/3R1M9ZO

Here it is! The penultimate episode in our "State of the Art" series. Join Peter and distinguished guests, Prof. Mervyn Singer and Dr. Martin Beed as they discuss the world of sepsis and the impact of COVID-19 on ICU trials.

Mervyn Singer is a ludicrously busy and accomplished intensivist and professor at University College London. He is a prolific and provocative publisher, researcher and innovator, and our go to guy for all things Sepsis, Syndromes and (basic) Science. This is a fun and informative chat: many thanks Merv!   Further Reading: 1. Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801-810. doi:10.1001/jama.2016.0287 2. Shankar-Hari M, Phillips GS, Levy ML, et al. Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):775-787. doi:10.1001/jama.2016.0289 3. Póvoa P, Coelho L, Dal-Pizzol F, et al. How to use biomarkers of infection or sepsis at the bedside: guide to clinicians. Intensive Care Med. 2023;49(2):142-153. doi:10.1007/s00134-022-06956-y 4. Singer M. Personalizing Sepsis Care. Crit Care Clin. 2018;34(1):153-160. doi:10.1016/j.ccc.2017.08.011 5. Singer M. Sepsis: personalization v protocolization?. Crit Care. 2019;23(Suppl 1):127. Published 2019 Jun 14. doi:10.1186/s13054-019-2398-5 6. Morelli A, Ertmer C, Westphal M, et al. Effect of heart rate control with esmolol on hemodynamic and clinical outcomes in patients with septic shock: a randomized clinical trial. JAMA. 2013;310(16):1683-1691. doi:10.1001/jama.2013.278477 7. Singer M, Shipley R, Baker T, Cowell A, Brealey D, Lomas D. The UCL Ventura CPAP device for COVID-19. Lancet Respir Med. 2020;8(11):1076-1078. doi:10.1016/S2213-2600(20)30422-7

In this episode of the podcast, we will discuss dogma in critical care medicine. How do we fight dogma when the evidence is weak? Our guest is Dr. Mervyn Singer, an internationally recognized critical care clinician, investigator, and educator. Dr. Singer is professor of intensive care medicine at University College London. Additional Resources: Challenging management dogma where evidence is non-existent, weak, or outdated. By D. A Hofmaenner and M. Singer https://link.springer.com/article/10.1007/s00134-022-06659-4 Link to Gapminder, an independent educational non-profit fighting global misconceptions https://www.gapminder.org/ Think Again: The Power of Knowing What You Don't Know. By Adam Grant https://amzn.to/3bceyLu Books Mentioned in this Episode: Factfulness: Ten Reasons We're Wrong About the World--and Why Things Are Better Than You Think. By Hans Rosling https://amzn.to/3S4kWFj

Sepsis is certainly a major cause of mortality and morbidity worldwide, but how common is it? Do we have any idea of true incidence and mortality? This talk will critically examine current epidemiology and ask the questions as to how many deaths are directly attributable, and how many are avoidable.

Join us for the first episode of UCL's new podcast, ‘Coronavirus: The Whole Story' with Vivienne Parry. Each week, we'll be looking at coronavirus through a different lens. This week we're exploring what happens inside intensive care. With special guests Professor Hugh Montgomery, Director of the UCL Institute for Human Health and Performance and Mervyn Singer, Professor of Intensive Care Medicine.For more info and transcripts, visit www.ucl.ac.uk/ucl-minds/podcasts/coronavirus See acast.com/privacy for privacy and opt-out information.

In our final (planned) COVID-19 episode, we are joined by intensivist Mervyn Singer, to discuss the treatments that were used in ICU for patients with severe COVID-19. In the first third we discuss the preparations that took place to get a London critical care unit ready for a pandemic. Then in the middle section, we delve into what treatments proved the most valuable, from invasive and non-invasive ventilation, proning, sedation and paralysis strategies, anti-coagulation and steroids. Finally, out attention shifts to what comes next, and the preparations being made for another wave or for a future pandemic. Do the UK's ICU bed numbers need to increase or should the emphasis be on High Dependency beds? The importance of training more staff in ICU level skills, that may be used outside of the ICU and lastly the UK's preparedness and the issues that arise with stockpiling.

Join us for the first episode of UCL’s new podcast, ‘Coronavirus: The Whole Story’ with Vivienne Parry. Each week, we’ll be looking at coronavirus through a different lens. This week we’re exploring what happens inside intensive care. With special guests Professor Hugh Montgomery, Director of the UCL Institute for Human Health and Performance and Mervyn Singer, Professor of Intensive Care Medicine. For more info and transcripts, visit https://www.ucl.ac.uk/ucl-minds/podcasts/coronavirus

Anyone who has heard UK intensivist Prof Mervyn Singer speak at an Intensive Care conference will no doubt enjoy listening to him speak on this episode of Mastering Intensive Care. Mervyn Singer is Professor of Intensive Care Medicine at University College London in the UK. He was born, bred, trained, and now works in London as an intensivist and a researcher whose career spans from basic mechanistic work through to translational investigations and multi-centre trials. He co-chaired the ‘Sepsis-3’ international definitions task force, is Editor-in-Chief of Intensive Care Medicine Experimental and Treasurer of the International Sepsis Forum. Mervyn has published widely in a variety of journals and has authored or co-edited several textbooks including the Oxford Textbook of Critical Care. He was the first UK intensivist to be awarded Senior Investigator status by the UK National Institute for Health Research, and to be invited to give plenary lectures at the European and US Intensive Care Congresses. In this conversation Mervyn is full of his usual enthusiasm as we covered many important topics including: How he became an intensivist What he’s observed about the physiological basis of intensive care The clinical ward round process he follows The scheme in his ICU to allow patients to die at home How he leads an end of life conversation The benefits to having an ICU-based psychologist How institutions might better care for their junior staff How much he enjoys his career His "can do" attitude How his passion for sport has helped him His regular sleep pattern The value he receives from doing body stretching His use of email and social media Mentoring younger trainees Which of his research makes him most proud His tips for giving a good lecture Some excellent advice to conclude our conversation   I invite you to listen in to my conversation with Mervyn Singer.   Andrew Davies   --------------------   About the Mastering Intensive Care podcast: The podcast is aimed to inspire and empower you to bring your best self to the intensive care unit, through conversations with thought-provoking guests. The hope is you’ll glean insights to move you closer towards being the best and most human healthcare professionals you can be, so you can make the most valuable contribution to your patient’s lives.   --------------------   Links related to Mervyn Singer Prof Mervyn Singer Mervyn Singer brief CV   Links to other resources (in order of mentioning) David Bennett's Obituary (co-authored by Mervyn Singer) Edith Piaf The Cricket “Ashes” New Normal Project podcast   Links related to Mastering Intensive Care podcast Mastering Intensive Care podcast - Episode 51 - A Recap of 2019 Mastering Intensive Care podcast - Episode 52 with Martin Bromiley Mastering Intensive Care podcast - Episode 53 with Paul Wischmeyer Mastering Intensive Care podcast - Episode 54 with Deborah Cook Mastering Intensive Care podcast Mastering Intensive Care page on Facebook Mastering Intensive Care at Life In The Fast Lane Andrew Davies on Twitter: @andrewdavies66 Andrew Davies on Instagram: @andrewdavies66 Andrew Davies on LinkedIn Email Andrew Davies Audio Producer Chris Burke Burke Sound & Media

Welcome to the final episode of Series 2 of Bolus. We are joined by Prof Mervyn Singer, a UCLH intensivist, researcher and teacher. He famously lead the international task force to redefine sepsis in 2016, known as Sepsis-3. Our wide ranging conversation covers a number of interesting and thought provoking questions: Is sepsis over diagnosed? Can you predict who will develop sepsis following an infection? Is a rapid, broad spectrum approach to antibiotics causing more problems than it solves? What's best for spotting sepsis at the bedside qSOFA or NEWS? Hyperlactataemia, is it always bad? How to assess for intravascular depletion and how should fluid resuscitation be administered? See you in 4 weeks for Series 3.

Session 9.3: Unconventional weapons: Nano, phages & more - Mervyn Singer, UK

Dr. Nitin Seam is joined by Drs. Vincent Liu and Mervyn Singer to discuss Dr. Liu's paper "The Timing of Early Antibiotics and Hospital Mortality in Sepsis”

Mervyn Singer discusses the new SEPSIS 3.0 definition at the Critical Care Reviews Meeting 2017, at Titanic, Belfast.

Session on 'Pathogen Detection and Sepsis Markers I' from the 1st World Sepsis Congress. Featuring Tom van der Poll, Beat Mueller, Dylan de Lange, Mervyn Singer, Jean-Paul Mira, Herwig Gerlach as chair, and Marvin Zick as your host.

Multiple biomarkers - physiological, biochemical, biological - can prognosticate early in critical illness, even in the ED. This implies the die is already cast (literally as well as figuratively) so we are simply prolonging death is those predetermined to die. We thus need to adopt a completely different strategy for such patients. This also applies to trial design, especially where survival is the endpoint.

The Mystery of MODS Summary By: Oli Flowers Mervyn Singer entertains the SMACC crowd with tales of MODS (Multi Organ Dysfunction Syndrome). With videos of Raquel Welch, stories from the Battle of Trafalgar and lessons from evolution, he makes us think about the important physiology underlying critical illness. This lecture precedes the latest SIRS definition and really puts them into context and leads on to the promise of precision medicine.

Interview with Clifford Deutschman, MD, MS, Mervyn Singer, MD and Derek Angus, MD, MPH, authors of The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

Is Suspended Animation only in the realms of science fiction, or is this a realsitic treatment option? Mervyn Singer questions if we can prevent secondary reperfusion injury following cerbral ischaemia.