Podcasts about Medical journal

What if you don't have trauma… and the mind-body connection is still the key to your healing? In this breakthrough mini episode, Brandy shares powerful insights from her session with the remarkable Mathias — a brilliant, grounded audio engineer with a sharp mind, a warm heart, and a deeply present energy. He came into the session clear-eyed and self-aware: he genuinely didn't have trauma. No heavy past to excavate. No layers to dig through. And yet, something was quietly affecting his body. Shoulder pain that spiked every night and kept him from sleeping. A blocked ear sensation that had lingered for a long time — no small thing for someone whose entire career depends on his hearing. What Mathias uncovered in this session is something that changes everything about how we understand healing — and it had nothing to do with trauma. It had to do with the feelings we manage so well, we don't even realize we're suppressing them. The worries we normalize. The frustrations we rationalize. The emotions we're just so good at keeping beneath the surface. In real time, Mathias was able to shift his shoulder pain to almost completely gone — and bring his blocked ear from a level 4 down to nearly clear. Because it's a reminder: you are so much more capable than you realize.     In This Episode You'll Discover Why you don't need trauma for the mind-body connection to be affecting your health The two biggest mistakes people make when trying to heal — and why one of them can actually make things worse The specific types of suppressed emotions that quietly impact the body, even when life looks stable on the surface Why mixed emotional signals are so easy to miss — and so important to address How Mathias created real, measurable shifts in his symptoms in real time     → Continue Your Self-Healing Journey Listen to the Full Volunteer Self-Healing Session Click here to access today's self-healing session as Brandy Gillmore works directly with Mathias Free Mind-Body Healing Training If you'd like a deeper understanding of mind-body healing and how self-healing works: Click here to join the FREE training. Brandy Gillmore's Mind-Body Healing: Scientific Research If you'd like scientific research on mind-body healing, you can view Brandy Gillmore's work published in a Medical Journal. Personal Empowerment and Self-Healing Courses If you're ready to heal yourself and change your life: Click here to explore our GIFT Mind-Body Healing™ and the GIFT Method™ Courses and GIFT Workshops.      Connect With Brandy Follow Brandy on Facebook Follow Brandy on Instagram Questions? Discover more at https://brandygillmore.com or email support@BrandyGillmore.com     Disclaimer, Safety & Protecting Our Work and Volunteers This content is provided for personal inspiration and self-healing support only. It is not medical advice and is not intended to diagnose, treat, prevent, or cure any condition. Do not change or discontinue any medical or mental health treatment without consulting your doctor(s). This content is for personal use only. In order to help protect our community, volunteers, and the integrity of the work, this content may not be recorded, copied, altered, redistributed, taught, impersonated, or used to create derivative works, including use with artificial intelligence (AI/ML) or similar technologies. By engaging with this content, you acknowledge and agree to these terms. (Click here to read the full disclaimer)

This week, we explore new evidence comparing oral anticoagulants for acute venous thromboembolism, treatment for chemotherapy-induced thrombocytopenia, and early results of gene therapy for inherited deafness. We also examine evolving strategies for chronic lymphocytic leukemia, review the management of polymyalgia rheumatica, and present a case discussion of a woman with chest pain, dyspnea, and syncope. We explore gastric cancer prevention, competency-based billing, the health consequences of immigration enforcement, access to high-cost gene therapies, and we present a Perspective on good compressions.

Ontario's expansion of online gambling and legalization of single-event sports betting were followed by a sharp rise in help-seeking for gambling problems, particularly among young men. A new CMAJ study, Help seeking for gambling problems following expansion of Ontario's online gambling market and legalization of single event sports betting, analyzes calls to Ontario's 24-hour mental health and addiction hotline before and after the 2022 policy changes. The findings suggest that increased accessibility, private-sector expansion, and in-play betting may be amplifying gambling-related harm.Dr. Daniel Myran, a family physician, research chair in family and community medicine at North York General Hospital, and co-author of the study, reports that hotline contacts among males aged 15 to 24 tripled after the market opened to private operators. By the end of the study period, more than 70% of callers cited online gambling. He describes how legalization of single-event sports betting and in-play betting reduced friction and increased immediacy, features linked to higher addiction risk. Dr. Daniela Lobo, medical lead of the Problem Gambling and Tech Use Clinic at CAMH and an assistant professor of psychiatry at the University of Toronto, describes seeing younger patients since the introduction of iGaming, including individuals in their late teens and early twenties. She explains how in-play betting mirrors other high-risk formats by offering rapid, repeated opportunities to wager. Gambling disorder shares features with substance use disorders, including tolerance, withdrawal symptoms, concealment, financial strain, and suicidal ideation. She also highlights medication-related risk, noting that dopamine agonists and certain atypical antipsychotics have been linked to new gambling behaviours.Clinicians should consider gambling when patients present with unexplained financial stress, relationship conflict, mood symptoms, or suicidality, and remain alert to medication-induced behavioural change. Resources like ConnexOntario offer anonymous referral support for patients and providers.For more information from our sponsor, go to HaleonHealthPartner.comComments or questions? Text us.Join us as we explore medical solutions that address the urgent need to change healthcare. Reach out to us about this or any episode you hear. Or tell us about something you'd like to hear on the leading Canadian medical podcast.You can find Blair and Mojola on X @BlairBigham and @DrmojolaomoleX (in English): @CMAJ X (en français): @JAMC FacebookInstagram: @CMAJ.ca The CMAJ Podcast is produced by PodCraft Productions

What happens when a hidden emotional pattern is quietly influencing your health, your relationships, and the way you see yourself? In this breakthrough episode, Brandy shares powerful insights from working with a live volunteer named Jas—a successful, driven woman who had been struggling with fibromyalgia and chronic pain that had taken over multiple areas of her life. Despite trying diet changes, supplements, and many different approaches to healing, nothing seemed to create lasting change. But during this session, something deeper surfaced. As Brandy began working with Jas's mind, a powerful pattern emerged—one that was subtly blocking healing and influencing how she saw herself and received love from others. When this pattern came into awareness, it created an important shift. Within the session, Jas experienced a dramatic reduction in pain—from about a level 6 down to nearly a 1—as several key mindset changes began to unfold. In this short breakthrough episode, Brandy shares one of the powerful insights that came from the session and explains how the way we relate to ourselves can quietly influence our health, our relationships, and our ability to truly thrive. You'll discover: A common self-love pattern that many people don't realize they have Why trying to "work around" emotional blocks often keeps them in place A powerful analogy that helps reveal how real transformation begins How shifts in mindset can influence both emotional and physical wellbeing This mini breakthrough episode shares one of the powerful insights that helped create a shift—and can help you open the door to deeper love, healing, and transformation in your own life.   → Continue Your Self-Healing Journey Listen to the Full Volunteer Self-Healing Session Click here to access today's self-healing session as Brandy Gillmore works directly with Jas Free Mind-Body Healing Training If you'd like a deeper understanding of mind-body healing and how self-healing works: Click here to join the FREE training. Brandy Gillmore's Mind-Body Healing: Scientific Research If you'd like scientific research on mind-body healing, you can view Brandy Gillmore's work published in a Medical Journal. Personal Empowerment and Self-Healing Courses If you're ready to heal yourself and change your life: Click here to explore our GIFT Mind-Body Healing™ and the GIFT Method™ Courses and GIFT Workshops.      Connect With Brandy Follow Brandy on Facebook Follow Brandy on Instagram Questions? Discover more at https://brandygillmore.com or email support@BrandyGillmore.com     Disclaimer, Safety & Protecting Our Work and Volunteers This content is provided for personal inspiration and self-healing support only. It is not medical advice and is not intended to diagnose, treat, prevent, or cure any condition. Do not change or discontinue any medical or mental health treatment without consulting your doctor(s). This content is for personal use only. In order to help protect our community, volunteers, and the integrity of the work, this content may not be recorded, copied, altered, redistributed, taught, impersonated, or used to create derivative works, including use with artificial intelligence (AI/ML) or similar technologies. By engaging with this content, you acknowledge and agree to these terms. (Click here to read the full disclaimer)

This week, we explore a phase 3 trial of finerenone in type 1 diabetes and chronic kidney disease and guidance on timing of nonculprit-lesion PCI after STEMI. We cover an investigational therapy for Dravet syndrome and neoadjuvant treatment for high-risk intrahepatic cholangiocarcinoma. We review the effects of radiotherapy on normal tissue, a puzzling case of progressive neurologic decline after suspected foodborne illness, and Perspectives on private equity, the AHEAD model, and medical credit cards.

In this episode of Heal Yourself. Change Your Life®, Brandy Gillmore shares powerful mind-body healing insights from working with an incredible volunteer named Doris who was experiencing vision loss. The first pattern? A buried emotion from decades ago that she thought was resolved — but was still silently affecting her health, her relationships, and even her vision. It's a perfect example of how unresolved emotional patterns can create a real stress response in the body, even years later. The second? Something millions of people do every single day — and when Brandy brought it up, Doris's response made her laugh because she said, "I thought that doesn't count." It counts. And once you hear why, you'll never look at it the same way. This episode explores how hidden emotional patterns — including guilt, buried anger, and everyday emotional triggers — can block self-healing and keep the body stuck in a cycle of illness. Brandy breaks down why true healing requires more than positive thinking and what it actually takes to rewire the mind-body connection at a deeper level. If you've been doing the inner work but still feel stuck, this episode might show you exactly what's been hiding in plain sight.     → Continue Your Self-Healing Journey Listen to the Full Volunteer Self-Healing Session Click here to access today's self-healing session as Brandy Gillmore works directly with Doris Free Mind-Body Healing Training If you'd like a deeper understanding of mind-body healing and how self-healing works: Click here to join the FREE training. Brandy Gillmore's Mind-Body Healing: Scientific Research If you'd like scientific research on mind-body healing, you can view Brandy Gillmore's work published in a Medical Journal. Personal Empowerment and Self-Healing Courses If you're ready to heal yourself and change your life: Click here to explore our GIFT Mind-Body Healing™ and the GIFT Method™ Courses and GIFT Workshops.      Connect With Brandy Follow Brandy on Facebook Follow Brandy on Instagram Questions? Discover more at https://brandygillmore.com or email support@BrandyGillmore.com     Disclaimer, Safety & Protecting Our Work and Volunteers This content is provided for personal inspiration and self-healing support only. It is not medical advice and is not intended to diagnose, treat, prevent, or cure any condition. Do not change or discontinue any medical or mental health treatment without consulting your doctor(s). This content is for personal use only. In order to help protect our community, volunteers, and the integrity of the work, this content may not be recorded, copied, altered, redistributed, taught, impersonated, or used to create derivative works, including use with artificial intelligence (AI/ML) or similar technologies. By engaging with this content, you acknowledge and agree to these terms. (Click here to read the full disclaimer)

This week, we explore a new standard of care for high-risk HER2-positive early breast cancer, long-acting therapy for people with HIV facing adherence challenges, a first-in-class trial of a p53 reactivator, and tecovirimat for mpox. We review group B streptococcal disease and a revealing case of prosthetic joint infection. Perspectives examine the role of folate therapy, Medicare drug-price negotiation, AI in medical education, and incidental findings.

She had read the book. She loved it. She even gave a copy to her doctor. She felt like she understood mind-body healing. But her pain was still there. In this episode of Heal Yourself. Change Your Life®, Brandy Gillmore shares powerful insights from working with Norma — a brilliant, strong woman in her eighties who had been living with what she called "just normal pain," something she believed she simply had to accept. Her neck pain began years ago after falling off a horse — and true to her nature, she got right back on. But here's what was remarkable: As Brandy worked with her, a hidden emotional trigger surfaced — someone close to her who had been "taking the mickey" for over 20 years — and her pain spiked to an 8. Then, as she genuinely shifted her emotional response, it dropped all the way down to a 1. In this episode, Brandy unpacks key takeaways, including: Why intellectual understanding isn't the same as emotional embodiment How subtle emotional patterns can quietly fuel chronic pain The difference between banter that connects and banter that wounds Why not taking something personally can create powerful shifts in your health This episode highlights the critical difference between knowing something… and truly shifting it. Here is a link to Brandy's book: Master Your Mind and Energy To Heal Your Body by Brandy Gillmore   → Continue Your Self-Healing Journey Listen to the Full Volunteer Self-Healing Session Click here to access today's self-healing session as Brandy Gillmore works directly with Kim Free Mind-Body Healing Training If you'd like a deeper understanding of mind-body healing and how self-healing works: Click here to join the FREE training. Brandy Gillmore's Mind-Body Healing: Scientific Research If you'd like scientific research on mind-body healing, you can view Brandy Gillmore's work published in a Medical Journal. Personal Empowerment and Self-Healing Courses If you're ready to heal yourself and change your life: Click here to explore our GIFT Mind-Body Healing™ and the GIFT Method™ Courses and GIFT Workshops.      Connect With Brandy Follow Brandy on Facebook Follow Brandy on Instagram Questions? Discover more at https://brandygillmore.com or email support@BrandyGillmore.com     Disclaimer, Safety & Protecting Our Work and Volunteers This content is provided for personal inspiration and self-healing support only. It is not medical advice and is not intended to diagnose, treat, prevent, or cure any condition. Do not change or discontinue any medical or mental health treatment without consulting your doctor(s). This content is for personal use only. In order to help protect our community, volunteers, and the integrity of the work, this content may not be recorded, copied, altered, redistributed, taught, impersonated, or used to create derivative works, including use with artificial intelligence (AI/ML) or similar technologies. By engaging with this content, you acknowledge and agree to these terms. (Click here to read the full disclaimer)

This week, we highlight major advances in multiple myeloma, gene therapy for cystinosis, and experimental treatments for myotonic dystrophy. We review long-term outcomes of aortic-valve replacement, strategies for secondary stroke prevention, and a revealing diagnostic case of eosinophilic disease in an older adult. A Sounding Board explores FDA approval standards. Perspectives delve into tobacco cessation, influenza evolution, and the uncertainty patients and clinicians share when facing life-altering diagnoses.

Sharyl speaks with Dr. Joseph Varon, who has started an independent medical journal. Unlike the big mainstream journals, he's not raking in money from the pharmaceutical companies whose sometimes questionable studies are published. Order Sharyl's new bestselling book: “Follow the $cience.” Subscribe to my two podcasts: “The Sharyl Attkisson Podcast” and “Full Measure After Hours.” Leave a review, subscribe and share with your friends! Support independent journalism by visiting the new Sharyl Attkisson store.

This week includes studies on promising new therapies for IgA nephropathy, evolving antithrombotic strategies after coronary stenting, and the inciting antigen in rare vaccine-related clotting syndromes. We review the urgent challenge of mucormycosis and follow the case of a young woman with headaches and hypertension. We discuss human-subjects research. Perspectives examine rural health, data interoperability, drug labels in the courts, and a pediatrician's dilemma.

On this episode of the CMAJ Podcast, Dr. Mojola Omole and Dr. Blair Bigham explore new evidence suggesting that rates of psychotic disorders are increasing in younger generations in Canada. Drawing on population-level data and broader psychiatric research, the episode examines how generational trends in psychosis intersect with substance use, social change, and the ongoing youth mental health crisis.Dr. Daniel Myran, a family physician and public health researcher at North York General Hospital, discusses findings from his CMAJ study, Incidence of psychotic disorders by birth cohort: a population-based cohort study in Ontario, Canada. He explains how overall rates of psychosis appear stable when populations are viewed as a whole, but mask a substantial rise among people born in the 1980s, 1990s, and early 2000s. Dr. Myran outlines possible contributors, including substance exposure, changes in diagnostic practices, and social determinants, and emphasizes the implications for early intervention psychosis programs and frontline care.The conversation then widens with Dr. Dafna Kahana, an associate professor of psychiatry at the University of Toronto and staff psychiatrist at CAMH, who draws on her article in the Journal of Psychiatry and Neuroscience, Are the kids alright? Making sense of the current youth mental health crisis in Canada through heuristic and data. She unpacks how social media use, sleep disruption, physical inactivity, pandemic-related isolation, and exposure to global crises may interact to affect youth mental health, while cautioning against oversimplified explanations or single-factor solutions.For clinicians, the takeaway is twofold: emerging generational shifts in psychosis warrant attention in both primary care and mental health planning, and addressing youth mental health requires a coordinated, multi-pronged approach that spans early identification, family support, and system-level investment rather than reliance on any single intervention.Comments or questions? Text us.Join us as we explore medical solutions that address the urgent need to change healthcare. Reach out to us about this or any episode you hear. Or tell us about something you'd like to hear on the leading Canadian medical podcast.You can find Blair and Mojola on X @BlairBigham and @DrmojolaomoleX (in English): @CMAJ X (en français): @JAMC FacebookInstagram: @CMAJ.ca The CMAJ Podcast is produced by PodCraft Productions

Welcome to this podcast from the Medical Journal of Australia. My name is Sally Block, the MJA's news and online editor. “The MJA acknowledges the Traditional Owners and Custodians of the land on which we live and work across Australia.  This podcast was recorded on the lands of the Gadigal people of the Eora Nation. I pay my respects to their Elders past and present.”  Today we will be talking about a type of trauma that generally can't be seen by the eye.  Complex trauma is defined as repeated, ongoing, and often extreme interpersonal trauma (between people) –  and it can involve violence, abuse, neglect or exploitation experienced as a child, young person and adult. The Blue Knot Foundation is a National Centre of Excellence for Complex Trauma. Joining me today is the Foundation's President and Managing Director Dr. Cathy Kezelman AM to talk about complex trauma and how clinicians can help patients who are affected by it.

This week, we look at new evidence on oral cholesterol-lowering therapy, the evolving role of beta-blockers after myocardial infarction, and advances in breast and prostate cancer treatment. We review the inherited risk of coronary disease. We also work through a revealing diagnostic case in a young woman and reflect on science under pressure, corporatized insurance, the reach of FDA law, and what it means to live with life-sustaining technology.

This week, we explore new therapies to reduce pancreatitis risk in severe hypertriglyceridemia, advances in breast cancer treatment, and long-term results of gene therapy for hemophilia B. We discuss vision-threatening vascular emergencies, the mental health effects of firearm injury on families, and care for peripheral artery disease. We also follow a revealing diagnostic case in an older woman with respiratory failure. Perspectives reflect on hypertension control, immunization access, chronic disease policy, and on the inherited risk of disease.

Remember when we were growing up and we'd hear things like “Better calm down, you're gonna give yourself an ulcer!” It was thought back then that stress and spicy food caused ulcers.Around 1979, Dr. Robin Warren and Barry Marshall started noticing these spiral-shaped bacteria while doing stomach biopsies of patients with gastritis.Then a crazy thing happened: The Easter Breakthrough.In 1982, a lab technician accidentally left their samples in the incubator for five days over the Easter holiday instead of the two-day standard at the time. This mistake allowed enough time for the H. pylori colonies to grow and appear.By 1983, Marshall had isolated the bacteria and found that it was present in 100% of the patients they tested who had ulcers. They had discovered the cause of ulcers.They presented their findings at a conference in Brussels. Their hope was that they had discovered a cure for an extremely painful disease that sentenced patients to a lifetime of eating bland foods and antacid pills.Marshall presented his findings at the conference in Brussels and the crowd celebrated his massive accomplishment. He received a standing ovation, he was Time's Person of the Year, millions of patients around the globe were cured, and Marshall was celebrated as a hero.Wait, I'm sorry, I got that wrong.The medical community viciously attacked him, saying that he was a “young nobody from Perth” who had no reputation, and senior doctors even called his theory “reckless and preposterous.” They said the stomach is a sterile environment and that no bacteria could survive in that acidic environment.Another group within the medical establishment believed that almost all diseases were “repressed emotional responses.” They said: “The critical factor in the development of ulcers is the frustration associated with the wish to receive love.”They literally thought ulcers were caused by people not getting enough love.Marshall was devastated, frustrated, and a bit angry that no one was listening to him, looking at the evidence, or—more importantly—helping the patients.Marshall attempted to perform studies to prove his theory, but the medical establishment kept throwing up roadblocks. In order to run a human test, he had to reproduce the results in animals first, but that didn't work in this case.So what did he do? He tested it on the “only ethical subject”: himself.In 1984, Marshall took the bacteria from an infected patient and drank it himself!After three days, he developed nausea and halitosis (extreme bad breath) because the bacteria neutralized his stomach acid. By day eight, an endoscopy showed massive stomach inflammation and colonies of the bacteria H. pylori.By day 10, the endoscopy found a raw, red, inflamed stomach lining. By day 14, Marshall began to fear for his health and started a therapy of antibiotics and bismuth.Marshall had just proven that H. pylori caused gastritis, and gastritis eventually causes ulcers.But even after the experiment, the medical establishment wouldn't surrender or change course!In 1985, he successfully published his self-experiment in the Medical Journal of Australia. But it was largely ignored.For a decade, ulcer victims had started talking about an “underground cure” called “the Marshall Treatment.” This was basically antibiotics.It wasn't for another full decade (1994) until the National Institutes of Health officially stated that most ulcers were caused by H. pylori and should be treated with antibiotics.This change effectively killed the billion-dollar market for long-term antacid maintenance, which Marshall later called “the ultimate satisfaction.”And it wasn't for another decade until Marshall received the Nobel Prize in 2005.Today, about half of the decline in stomach cancer is attributed to Marshall's discovery.Marshall's discovery was ignored for a decade. What was the impact of that? Let's look at some numbers.At that time, about 700,000 people died from stomach cancer per year. Let's say just a modest 25% of those could be saved by Marshall's solution of “Screen and Treat” with antibiotics.That means that at least 1,000,000 to 2,000,000 people may have been saved if Marshall's discovery had been recognized earlier.Thankfully, in 2005, Marshall and his colleague Robin Warren were awarded the Nobel Prize in Physiology or Medicine.Because of Marshall and Warren's work, the World Health Organization (WHO) now classifies H. pylori as a carcinogen. This discovery also sparked the first “antibiotic cure” for a cancer. A rare type of stomach tumor called MALT lymphoma can often be completely cured just by taking antibiotics to kill the bacteria.I love this story because it's a perfect case study in how the “experts” can be dead wrong for decades. It's a classic case of “appeal to authority,” where “experts” dismissed the correct answer, not because of fundamental truth, but only because Marshall was not a part of their Tribe. He wasn't an “expert”. It's a reminder that people that change the world and make massive discoveries are often considered heretics, stupid, evil, or worse. The establishment chose to believe ulcers were caused by a “lack of love” rather than a bacteria because their dogma was profitable and comfortable. It is another reminder that the system isn't built to find the truth. It is built to protect itself and if you want to do something great or different, it could take you decades of being called a monster before anyone ever believes you. Just ask Alan Turing or Galileo. I'm very sorry for the lack of updates lately. Santa brought our 7 year old a ATV 4-wheeler for Christmas and I flipped it and broke 3 ribs. I'm recovering now but it was a rough patch there. Thank you for your patience! Year Of The Opposite - Travis Stoliker's Substack is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Get full access to Year Of The Opposite - Travis Stoliker's Substack at www.yearoftheopposite.com/subscribe

In this episode, we explore evolving evidence on anticoagulation after atrial fibrillation ablation, long-term outcomes with immunotherapy for melanoma, and promising new treatments for hepatitis D and triple-negative breast cancer. We review advances in physiologic pacing for heart failure and work through a challenging case involving fever, rash, and neurologic symptoms. An article considers fairness for late-career physicians, and Perspectives discuss misconceptions about autism, access to contraception, and the financial pressures shaping health care.

This week, we explore new evidence on managing asymptomatic carotid stenosis, restoring vision in advanced macular degeneration, and preventing migraine in children. We discuss innovative cellular therapy for autoimmune disease, review sudden cardiac arrest in athletes, and describe a case of severe systemic infection with vision loss. Perspectives examine global tobacco risks, the future of telehealth payment, Medicare coverage of new technologies, and the things physicians carry.

On this episode of the CMAJ Podcast, Dr. Mojola Omole and Dr. Blair Bigham examine the issues raised in a recent CMAJ commentary on Alberta's Compassionate Intervention Act, which explores the ethical and clinical implications of this approach to involuntary treatment. As governments across Canada turn to coercive measures in response to the overdose crisis, the episode considers what these policies mean for patient autonomy, clinical practice, and the role of physicians in enforcing care.Dr. Bonnie Larson, a family physician and addictions medicine specialist at the University of Calgary, joins the conversation to unpack the legislation. She explains how the Act allows individuals to be detained and treated even when they are deemed capable of making their own medical decisions. Dr. Larson describes how this represents a substantial departure from established principles of consent and autonomy, placing physicians in ethically complex positions and reshaping their role in care.The discussion then turns to Massachusetts, where involuntary treatment for substance use has existed for decades under Section 35. Dr. Keren Ladin, a bioethicist and health services researcher at Tufts University, reveals the experiences of clinicians working within this framework. Drawing on her research, she describes how Section 35 has shaped clinical practice, contributed to moral distress among healthcare providers, and often resulted in people being treated in carceral rather than therapeutic settings.Together, the guests reflect on what these policies reveal about how societies respond to addiction, the limits of coercive care, and the risks of prioritizing control over evidence-based, patient-centred treatment.Comments or questions? Text us.Join us as we explore medical solutions that address the urgent need to change healthcare. Reach out to us about this or any episode you hear. Or tell us about something you'd like to hear on the leading Canadian medical podcast.You can find Blair and Mojola on X @BlairBigham and @DrmojolaomoleX (in English): @CMAJ X (en français): @JAMC FacebookInstagram: @CMAJ.ca The CMAJ Podcast is produced by PodCraft Productions

This week, we explore new options in cardiovascular prevention, fish-oil supplementation in dialysis patients, RSV vaccination, and cutting-edge cellular therapy for leukemia. We discuss advances in lung cancer treatment, approaches to functional dyspepsia, and a complex case of severe infection after travel. Perspectives examine access to and cost of weight-loss drugs, the promise and risks of AI in clinical care, and what it means to care for others while carrying personal loss.

This week, we share advances in treatment for EGFR-mutated lung cancer, a brain-penetrant enzyme therapy for a rare pediatric disorder, and dual targeting of extramedullary myeloma. We review cardiogenic shock, work through a challenging diagnostic puzzle in a young woman with recurrent illness, and explore Perspectives on corporatized care, vaccine policy, AI in medicine, and where clinicians carry grief.

On this ENCORE of our most popular episode of 2025, hosts Dr. Mojola Omole and Dr. Blair Bigham speak with two authors of the latest “Hypertension Canada guideline for the diagnosis and treatment of hypertension in adults in primary care”The discussion reflects a shared urgency: despite past successes, Canada's hypertension control rates are declining. The new guidelines aim to reverse this trend by simplifying diagnosis and treatment for frontline clinicians.Dr. Rémi Goupil, a nephrologist and clinician researcher at Sacré-Cœur Hospital in Montreal, and Dr. Greg Hundemer, a nephrologist and clinician scientist at The Ottawa Hospital, explain that the updated guideline is deliberately designed for primary care providers. They highlight key shifts: lowering the diagnostic threshold for hypertension to  ≥ 130/80 mm Hg, simplifying blood pressure targets, and emphasizing accurate, standardized measurement techniques both in clinic and at home. The guidelines were created with input from a majority-primary care committee—including family physicians, nurses, pharmacists, and patient partners—to ensure clinical applicability.Together, the panel outlines a streamlined nine-step treatment algorithm, emphasizing combination therapy as first-line pharmacologic management. They explain the evidence supporting ARB–thiazide combinations, discuss cost considerations for drug selection, and address adherence challenges. They also explore red flags for secondary hypertension and how the algorithm supports—but does not replace—clinical judgment.For physicians, this guideline offers a clear and practical roadmap: measure blood pressure correctly, aim for systolic pressure below 130 mm Hg, and use the simplified treatment sequence to improve adherence and outcomes. Designed to be easy to implement, the new approach aims to empower primary care providers to act with confidenceComments or questions? Text us.Join us as we explore medical solutions that address the urgent need to change healthcare. Reach out to us about this or any episode you hear. Or tell us about something you'd like to hear on the leading Canadian medical podcast.You can find Blair and Mojola on X @BlairBigham and @DrmojolaomoleX (in English): @CMAJ X (en français): @JAMC FacebookInstagram: @CMAJ.ca The CMAJ Podcast is produced by PodCraft Productions

This week, we look at ctDNA-guided immunotherapy for bladder cancer, cardiovascular outcomes with tirzepatide, and evidence that one HPV vaccine dose may be enough. We explore high-dose rifampin for tuberculous meningitis, review measles amid rising outbreaks, and follow a challenging case of gastrointestinal bleeding. Essays examine how clinicians navigate post-Dobbs care, tobacco harm among people with mental illness, congenital syphilis, and sustaining medical research.

Despite a range of effective prevention tools, HIV incidence continues to rise in Canada, with stark disparities across ethnicity, gender, Indigeneity and geography. Updated Canadian guidelines on HIV pre- and post-exposure prophylaxis reflect scientific advances since 2017 and address both new formulations and persistent barriers to equitable access.Dr. Darrell Tan, lead author and clinician scientist at St. Michael's Hospital, outlines several prophylaxis options now available. Daily oral tenofovir disoproxil fumarate with emtricitabine is close to 100 per cent effective with perfect adherence and remains forgiving of occasional missed doses. Long-acting injectable cabotegravir, administered every two months, shows even greater effectiveness in trials largely because it reduces the adherence challenges associated with daily pills, though cost and availability continue to limit uptake.Natasha Lawrence, a community health worker at Women's Health in Women's Hands Community Health Centre in Toronto, reports that most women she serves have never heard of pre-exposure prophylaxis. Many people perceive their HIV risk as low until discussions explore relationship dynamics, including uncertainty about partner fidelity or difficulty negotiating condom use. She highlights how power imbalances and gender-based violence shape women's risk and may limit the practicality of daily pills. Long-acting injectables can offer greater privacy and autonomy for some women, reducing the risk of partner detection. Public health messaging, she stresses, must be co-designed with communities to ensure cultural relevance and avoid stigma.Clinicians should initiate sexual health conversations routinely, not only when patients raise concerns. Pre-exposure prophylaxis can be discussed during visits for contraception, mental health or other routine care. When patients express interest, access should not be limited by rigid criteria. Long-acting options may be especially helpful for women who face safety or privacy concerns in their relationships.For more information from our sponsor, go to medicuspensionplan.comComments or questions? Text us.Join us as we explore medical solutions that address the urgent need to change healthcare. Reach out to us about this or any episode you hear. Or tell us about something you'd like to hear on the leading Canadian medical podcast.You can find Blair and Mojola on X @BlairBigham and @DrmojolaomoleX (in English): @CMAJ X (en français): @JAMC FacebookInstagram: @CMAJ.ca The CMAJ Podcast is produced by PodCraft Productions

This week, we look at new studies on high-dose influenza vaccines for older adults, antiplatelet therapy after coronary surgery, and HER2-targeted immunotherapy for advanced bladder cancer. We review complex regional pain syndrome and a pediatric case of fever and rash. We also explore FDA innovation and safety, aspirin's role in metastasis prevention, the meaning of “the good doctor,” smallpox in the Revolution, and how AI may reshape medical science.

This week, we look at new trials on glucocorticoids for pneumonia in Africa, shunting for normal-pressure hydrocephalus, and pegcetacoplan for two rare kidney diseases. We review updated vaccine evidence for Covid-19, RSV, and influenza, and present a case of respiratory decline and muscle weakness. Perspectives explore health care incentives, U.S. global health strategy, and bringing AI-enabled care to rural America.

Celiac disease affects between one and two percent of Canadians, yet many patients wait years before receiving a clear diagnosis. On this episode of the CMAJ Podcast, the hosts speak with two contributors to the CMAJ review article Diagnosis and management of celiac disease about the condition's diverse clinical presentations, appropriate testing strategies, and the practical realities of long-term dietary management.Jedid-Jah Blom, a registered dietitian at the McMaster Celiac Disease Clinic and researcher at the Farncombe Family Digestive Health Research Unit at McMaster University, shares her own experience being diagnosed and living with celiac. She explains how patients must identify hidden gluten sources in ingredients like dextrin and malt, and why cornmeal or corn flour products may be contaminated. Blom outlines the risks of cross-contamination and dining out challenges, emphasizing whole gluten-free grains over processed products that lack fortification.Dr. Maria Ines Pinto-Sánchez, a gastroenterologist at Hamilton Health Sciences and director of the Celiac Clinic at McMaster University, explains why celiac is called a chameleon disease. She notes that about 30 percent of patients present with gastrointestinal symptoms, while others may have brain fog, fatigue, or anemia. She describes how TTG antibodies plus total IgA are used for screening, with positive results requiring endoscopy and biopsies for confirmation. Dr. Pinto-Sánchez emphasizes that patients should not start a gluten-free diet before testing. She discusses ongoing monitoring including TTG levels, bone density, and nutrient deficiencies.For physicians, the discussion highlights the need for a low threshold when testing TTG antibodies in patients with unexplained fatigue, brain fog, or gastrointestinal symptoms. Both guests stress the importance of completing diagnostic testing before patients begin a gluten-free diet and arranging early dietitian referral.Comments or questions? Text us.Join us as we explore medical solutions that address the urgent need to change healthcare. Reach out to us about this or any episode you hear. Or tell us about something you'd like to hear on the leading Canadian medical podcast.You can find Blair and Mojola on X @BlairBigham and @DrmojolaomoleX (in English): @CMAJ X (en français): @JAMC FacebookInstagram: @CMAJ.ca The CMAJ Podcast is produced by PodCraft Productions

This week, we look at new studies on early aspirin discontinuation after myocardial infarction, an antiviral pill for dengue prevention, and CRISPR-based gene editing for lipid disorders. We review bedside clinical teaching and present a complex case of seizures and visual disturbances. Perspectives explore antidepressant safety in pregnancy, restoring trust in public health, academic medical centers' venture investments, and a young physician's wrinkled white coat.

This week, we look at new research on potassium optimization in patients with defibrillators, reducing antihypertensive therapy in nursing homes, an mRNA influenza vaccine, and belzutifan for rare neuroendocrine tumors. We review long QT syndrome and present a case of abnormal behavior and seizures in a young man. We also explore perspectives on primary care reform, tobacco cessation in HIV and tuberculosis care, corporate control in health care, and the simple power of compassion with ice cream.

This episode of the CMAJ Podcast explores how physician identity can influence patient expectations, and how those expectations may contribute to gender, race, and immigration status pay gaps. The discussion builds on the CMAJ article “Family physician pay inequality: a qualitative study exploring how physician responses to perceived patient expectations may explain gender, race, and immigration status pay differences”.Dr. Monika Dutt, a family physician, public health and preventive medicine specialist, and PhD candidate in health policy at McMaster University, explains how the study's interviews with 55 family physicians across Ontario revealed patterns linking patient expectations to physician identity. She describes how gender and cultural background influence the types of visits physicians are asked to provide, and how these interactions may affect their earnings under fee-for-service models.Dr. Meredith Vanstone, professor in the Department of Family Medicine at McMaster University, outlines how physicians adapt to explicit and inferred patient expectations and the income implications that follow. She discusses how these expectations are shaped by identity and why the resulting adjustments in care can lead to financial penalties for some physicians while improving patient relationships and trust.The guests highlight how remuneration structures can either amplify or mitigate these inequities. They suggest that moving toward salary or time-based models could help reduce the impact of physician identity on income while supporting equitable, patient-centred care.For more information from our sponsor, go to medicuspensionplan.comComments or questions? Text us.Join us as we explore medical solutions that address the urgent need to change healthcare. Reach out to us about this or any episode you hear. Or tell us about something you'd like to hear on the leading Canadian medical podcast.You can find Blair and Mojola on X @BlairBigham and @DrmojolaomoleX (in English): @CMAJ X (en français): @JAMC FacebookInstagram: @CMAJ.ca The CMAJ Podcast is produced by PodCraft Productions

In this episode, we look at new trials on deferring arterial catheterization in shock, beta-blocker use after myocardial infarction, and a treatment for triple-negative breast cancer. We review acromegaly. A case describes a man with dyspnea, edema, and pacemaker lead displacement. We explore perspectives on the burdens of primary care, the erosion of harm reduction, child health policy, and the meaning of hospice.

In this episode, we discuss long-term outcomes after chest-wall irradiation for breast cancer, new treatments for psoriasis and obesity, and early results on a vaccine for Lassa fever. We review opioid deprescribing and a clinical case describes spiraling into a distant past. Perspectives examine the corporatization of health care, the health effects of new energy legislation, and Medicaid cuts affecting U.S. children.

Wesley J. Smith of the Discovery Institute Wesley Smith's National Review Columns Culture of Death: The Age of “Do Harm” Medicine Forced Exit: Euthanasia, Assisted Suicide and the New Duty to Die The post An Assisted Suicide Bill in Illinois & A Medical Journal Article on Compassionate Release of Violent Criminals – Wesley Smith, 11/4/25 (3081) first appeared on Issues, Etc..

A recent article in CMAJ, Mental health service use among Black adolescents in Ontario by sex and stress level: a cross-sectional study, reveals how patterns of mental health service use among Black youth shift with the level of psychological distress. Lead author Mercedes Sobers, a PhD candidate in epidemiology at the Dalla Lana School of Public Health and research coordinator at the Centre for Addiction and Mental Health, joins the podcast to unpack the findings and their implications.The study found that Black male youth had higher odds of accessing services than white male youth when at low levels of distress but lower odds of accessing services at high levels. Black female youth had lower odds of service use than white female youth at both low and high distress levels. Mercedes explains how these patterns may reflect how behaviour is interpreted: Black boys may be referred to services more often at lower distress levels but steered toward more punitive responses when distress rises. For Black girls, she points to adultification and cultural mismatches in care.Dr. Amy Gajaria, a psychiatrist at the Centre for Addiction and Mental Health and associate scientist in the Margaret and Wallace McCain Centre for Child, Youth and Family Mental Health, describes how programs like AMANI aim to provide culturally adapted care and build trust with Black youth. She shares how early encounters with the system can shape future engagement with care.For physicians, the discussion underscores the importance of culturally sensitive care that embraces and reflects the experiences of Black youth, creating more meaningful and effective pathways to support.Comments or questions? Text us.Join us as we explore medical solutions that address the urgent need to change healthcare. Reach out to us about this or any episode you hear. Or tell us about something you'd like to hear on the leading Canadian medical podcast.You can find Blair and Mojola on X @BlairBigham and @DrmojolaomoleX (in English): @CMAJ X (en français): @JAMC FacebookInstagram: @CMAJ.ca The CMAJ Podcast is produced by PodCraft Productions

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning explores the integration of artificial intelligence (AI) in writing medical articles. Chapters 00:00 Intro 01:56 Using AI in Medical Writing 09:07 JANS 1, AI-Writing Article 14:53 JANS 2, Kidney vs Lung Transplant Outcomes 17:04 JANS 3, Harvesting Tech on ITAG 18:56 JANS 4, Phase 2 NeoCOAST-2 Trial 23:01 Career Center 23:41 Video 1, TAVR Explant After CABG w MVR 25:28 Video 2, Updated Y-Incision AA Enlargement 27:05 Video 3, Carotid Artery Cann for CABG 28:16 Upcoming Events He reviews guidelines set by the International Committee of Journal Editors Committee regarding publication ethics and emphasizes the benefits of utilizing AI in writing processes. Joel also highlights the crucial necessity of including disclosures when employing AI tools. Additionally, he delves into other ways AI can be used, such as data analysis, and discusses taking accountability when using these technologies. Furthermore, he addresses the limitations of AI, noting that it cannot be cited as a source or used as a coauthor.   Joel also highlights recent JANS articles on assisted artificial intelligence in medical writing, the impact of kidney transplantation on survival outcomes for lung transplantation, if the harvesting technique affects the production of nitric oxide and endothelin in the internal thoracic artery graft, and the platform phase 2 NeoCOAST-2 trial on perioperative durvalumab plus chemotherapy plus new agents for resectable non-small-cell lung cancer.  In addition, Joel explores a TAVR explant after CABG with MVR, tips and tricks for the updated Y-incision aortic annular enlargement, and carotid artery cannulation for cardiopulmonary bypass in minimally invasive cardiac surgery.    JANS Items Mentioned  1.) Assisted Artificial Intelligence in Medical Writing: A Primer for Humans   2.) The Impact of Kidney Transplantation on Survival Outcomes for Lung Transplantation  3.) The Harvesting Technique Affects the Production of Nitric Oxide and Endothelin in the Internal Thoracic Artery Graft  4.) Perioperative Durvalumab Plus Chemotherapy Plus New Agents for Resectable Non-Small-Cell Lung Cancer: The Platform Phase 2 NeoCOAST-2 Trial  CTSNet Content Mentioned  1.) TAVR Explant After CABG With MVR   2.) Tips and Tricks for the Updated Y-Incision Aortic Annular Enlargement   3.) Carotid Artery Cannulation for Cardiopulmonary Bypass in Minimally Invasive Cardiac Surgery   Other Items Mentioned  1.) Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals  2.) Perfecting TAVR Removal | Skills Sharpening With Vince Gaudiani  3.) Resident Video Competition  4.) Career Center   5.) CTSNet Events Calendar  Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

This week, we look at new findings from the European prostate cancer screening study, advances in lung cancer therapy, physical therapy for meniscal tear, and a promising vaccine for Salmonella Paratyphi A. We review noninvasive liver fibrosis assessment and a complex clinical case, and explore perspectives on concierge care, kidney disease equity, WIC enrollment, community health, FDA regulation, and standing with colleagues in Gaza.

In this episode, we look at new research on mucoactive therapy for bronchiectasis, aspirin use in anticoagulated patients with coronary disease, and sotatercept for early pulmonary arterial hypertension. We explore the genetics behind misdiagnosed common diseases and review uncertainty in medical training. We also share a case of woman with abdominal distention, edema, and pleural effusions and Perspectives on sickle cell disease, fetal personhood, and living with a genetic diagnosis.

In this episode, we look at new research in cervical cancer, lupus, gene therapy for immune deficiency, and malaria prevention in infants. We review hair loss in women, follow a case of tuberculosis in advanced HIV, and hear perspectives on vaccines, primary care, digital health, infection surveillance, AI in disaster response, Medicare policy, and bearing witness in conflict zones.

In this episode, we explore new treatments for hypertension, hereditary amyloidosis, and malaria prevention, along with insights on mosquito-borne disease control. We review idiopathic intracranial hypertension, follow a striking case of a hidden foreign body, and hear perspectives on worker safety, immigrant health care, the role of pharmaceutical wholesalers, and the arc of a medical career.

Featuring articles on severe acute malnutrition with gastroenteritis in children, medical imaging and pediatric cancer risk, moderate hypertriglyceridemia, preventing RSV disease in healthy infants, and treating hypertension in rural South Africa; a review article on monoclonal gammopathy of undetermined significance; a Clinical Problem-Solving on a shifting frame; and Perspectives on insight into corporate governance, on pharmaceutical tariffs, and on OUD medications.

Welcome to this podcast from the Medical Journal of Australia. My name is Sally Block, the MJA's news and online editor. “The MJA acknowledges the Traditional Owners and Custodians of the land on which we live and work across Australia.  This podcast was recorded on the lands of the Gadigal people of the Eora Nation. I pay my respects to their Elders past and present.” Between 1968 and 1970, Australia was hit by a pandemic known as the Hong Kong Flu. The MJA is publishing an historical piece about the pandemic and its impact. Dr John Gerrard is the Infectious Diseases Physician at the Gold Coast University Hospital and  former Chief Health Officer of Queensland.

Featuring articles on heart failure, provoked venous thromboembolism, chronic lymphocytic leukemia, and acute ischemic stroke; a review article on medical education to improve diagnostic equity; a case report of a man with embolic stroke and left ventricular apical aneurysm; two articles on the 2025 Lasker–DeBakey Clinical Medical Research Award; and Perspectives on structural and scientific racism, on the Gates Foundation's final chapter, and on Dr. Kolhouse and the cowboy.

Featuring articles on PI3K-altered colorectal cancer, type 2 diabetes, oral semaglutide, and proportional-assist ventilation; a review article on tumor lysis syndrome; a case report of a girl with chest pain and bone and liver lesions; and Perspectives on integrating pharmacotherapy into tobacco control, on Medicaid enrollees with chronic conditions, and on ultraprocessed food.

Featuring articles on hypertrophic cardiomyopathy, rehabilitation after myocardial infarction in older adults, the 2024 Marburg virus disease outbreak in Rwanda, and medications for opioid use disorder in county jails; a case report of a woman with dyspnea and fatigue; a Medicine and Society on the race-correction debates; and Perspectives on recent efforts toward equity, on medical research funding in a divided America, and on the end of days.

Featuring articles on obesity, type 1 diabetes, syphilis, and heparin-induced thrombocytopenia; a review article on the management of acute type B aortic dissection; a Clinical Problem-Solving describing a fruitful workup; and Perspectives on the corporatization deal, on advancing physician-scientist training in China, and on the rise of drug innovation in China.

Featuring articles on lung cancer, vasomotor symptoms in breast cancer, autoimmune pulmonary alveolar proteinosis, and high-risk cutaneous squamous-cell carcinoma; a review article on educational strategies for clinical supervision of AI use; a case report of a woman with fatigue and myalgias; a Sounding Board on vaccine policy in the U.S.; and Perspectives on preventive care at the Supreme Court, regulating private equity in health care, reforming the prescription drug user fee program, and on the consultant.

Featuring articles on overweight, obesity and diabetes; lactated Ringer's solution versus normal saline; and spinal muscular atrophy; a review article on metabolic dysfunction–associated steatotic liver disease; a case report of a woman with respiratory failure and abnormal chest imaging; and Perspectives on dismantling public health infrastructure, on progress lost, on private law in American health care, and on the serendipitous dance between life and death.

Featuring articles on treatments for chronic kidney disease and type 2 diabetes, bubonic plague, and advanced breast cancer; a review article on hypogonadism; a Clinical Problem-Solving describing gasping for strength; a Medicine and Society on the infant mortality rate; and Perspectives on profit-driven medicine, on lead contamination in Milwaukee schools, on training health communicators, and on ER and becoming a physician.

Featuring articles on myeloma, mitochondrial DNA disease, cardiac surgery, and squamous-cell carcinoma; a review article on motor vehicle crash prevention; a case report of a woman with seizure-like activity and odd behaviors; a Medicine and Society article on the evaluation of occupational pulmonary impairment; and Perspectives on Covid-19 vaccines, on public policies, and on living on the edge of the valley of the sick.