Podcasts about Sepsis

This week, Aebhric O'Kelly speaks with Dr Travis Kaufman and they explore his 25-year US Army career, his transition from combat engineer and military diver to Physician Assistant (PA), and five years providing medical support through the White House Medical Unit.Travis describes one of the most difficult lessons emerging from Ukraine: prolonged tourniquet use. A Ukrainian medic explains the decision as “triage of the limb or the life” when attempting tourniquet conversion after several hours may place the casualty at considerable risk.The discussion examines unnecessary tourniquet use, the importance of reassessment, contaminated wounds and the increasing problem of sepsis when evacuation is delayed for hours or days. Travis argues that the traditional TCCC assumption of rapid evacuation can create a training scar when casualties instead remain with combat lifesavers and medics for prolonged periods.The episode then explores what PCC actually looks like in practice: trending observations, wound debridement, antimicrobial planning, pain management, positioning, pulmonary care and the fundamental nursing interventions that can determine whether a casualty deteriorates.Travis also shares examples of improvisation from the field, including improvised PEEP and wound-vacuum techniques, and discusses why clinicians need to rediscover simple solutions when sophisticated equipment is unavailable.Chapters00:00 – Meet Dr Travis Kaufman: From Army diver to PA, White House medicine and Ukraine.02:26 – Becoming a Military Deep-Sea Diver: Training, attrition and operational diving.06:12 – From Diver to Physician Assistant: Changing careers and entering military medicine.07:15 – What Is a Physician Assistant?: Origins, training and the military PA role.10:38 – PA vs Nurse Practitioner: Different educational and clinical models.13:06 – Advising Across Eastern Europe: Building capability and interoperability.14:19 – Inside the White House Medical Unit: Medical support for the President and First Family.15:35 – Medical Planning for the President: Preparing for presidential travel worldwide.17:32 – Training for High-Consequence Medicine: Trauma preparation and live-tissue training.19:43 – Humanitarian Medicine in Tanzania: Wilderness medicine and community healthcare.21:00 – Schistosomiasis and Sickle-Cell Care: Managing disease in resource-limited communities.24:40 – HIV and the Problem of Follow-Up: When treatment exists but access remains difficult.27:07 – Inside a Ukrainian Stabilisation Point: Damage-control resuscitation with limited resources.28:45 – The Limb or the Life: The realities of prolonged tourniquet use.30:00 – Preventing Unnecessary Limb Loss: Tourniquet reassessment and conversion.31:56 – Sepsis in Prolonged Casualty Care: The consequences of delayed evacuation.33:30 – Debridement Without Water: Managing contaminated battlefield wounds.34:47 – Airways with Limited Equipment: Facial trauma and conserving resources.36:14 – Taking PCC to the CLS and CMC: Moving prolonged-care skills further forward.39:09 – What Should a Two-Day PCC Course Teach?: Reassessment, wounds and prolonged-care thinking.40:45 – Stop Taking Snapshots — Start Trending: Following physiology over time.42:13 – The “Boring” Care That Saves Lives: Nursing care, positioning, pain and pulmonary management.43:40 – Improvised PEEP and Wound VACs: Field-expedient solutions when equipment runs out.45:13 – Rediscovering Old Lessons: What previous wars may teach modern austere medicine.46:27 – Medicine in the Mediterranean: Travis previews his keynote presentation.47:45 – “Sir, Are We Gonna Be Okay?”: Trust, responsibility and caring for severely wounded soldiers.49:49 – Advice for the Austere Clinician: Lose the ego, stay curious and learn from experience.

This is a quick review of SIRS vs sepsis vs septic shock, including what distinguishes each from the next, the earliest clinical signs of this whole progression (hint: it's not hypotension), and why knowing these things matters. ___________________ ⁠Nursing School Survival Blueprint⁠ - Feeling overwhelmed or unsure how to approach nursing school? Download this free Blueprint to understand exactly what's working against you — and what to do instead. Straight A Nursing Study Resources⁠⁠ - ⁠Check out everything Straight A Nursing has to offer, including free resources and online courses to help you succeed!

Die Sepsis, umgangssprachlich auch Blutvergiftung genannt, ist eine der häufigsten Todesursachen in Deutschland. Trotzdem wird die Erkrankung oft unterschätzt und vom medizinischen Fachpersonal manchmal nicht rechtzeitig erkannt. Mittlerweile kann die KI die Diagnose beschleunigen – und dadurch Leben retten. Christoph König im Gespräch mit Prof. Jens Werner, Präsident der Deutschen Gesellschaft für Chirurgie e. V.

Note: This is a re-release of one of our most-listened to episodes — originally recorded Autumn 2025. We've given it a new edit because it's more relevant than ever.If you know you need to do something about how you're feeling — but you keep telling yourself "not yet" — this is for you. We are very good at spotting danger in other people. Sepsis, red flags, a patient or client deteriorating. We act fast. With ourselves, we don't. We wait until it becomes catastrophic — a patient or client complaint, an error because our brain isn't working properly, our health going — before we give ourselves permission to act. This episode is about why doing nothing feels safer, why it isn't, and how to make the next step small enough you can actually take it. Not handing in your notice. One doable thing.Download the free Burnout Self-Assessment Toolkit — work through it as you listen: https://youarenotafrog.com/toolkit/We cover:• Why we spot burnout and overwhelm in everyone else but not in ourselves• The three psychological traps that keep high achievers stuck: status quo bias, loss aversion, and sunk cost — including the thought "I've given 10 or 20 years to this, I can't stop now"• Why our ingrained programming tells us the misery we know is safer than the uncertainty we don't — and how that will affect your next decision, and the one after that• Why waiting has a cost too — your health, your relationships, your character — and why that cost keeps going up and can be devastating• How to decide your line before burnout decides it for you — your "kill criteria" — so you don't wait for catastrophe• How to make the next step small enough you can actually take it: one conversation you've been avoiding, one boundary, one phone call to a trusted person — shame shrinks when you speak itThis episode is for you if you are a high achiever in a leadership role who has to have the conversation nobody else will, has to make the call someone disagrees with, or lies awake replaying a decision you had to make — and you can feel the heat building, but you keep telling yourself to keep going.Hosted by Rachel Morris | You Are Not a Frog - for high achievers who want to care deeply and carry less.Get weekly tools and episode notes by email: https://youarenotafrog.com/welcomeMore resources: https://youarenotafrog.com/Burnout Self-Assessment Toolkit: https://youarenotafrog.com/toolkit/#burnout #burnoutrecovery #highachieversMentioned in this episode:

Join our hosts for Monday's show from 4-6pm where we will be discussing: ‘Homelessness' and ‘Sepsis'. Homelessness Andy Burnham has pledged to end rough sleeping, with a major push to get people off the streets by Christmas. But is providing accommodation enough, or does lasting change require tackling the causes of homelessness? Join us as we explore the challenge of rough sleeping, rehabilitation and how society can help people rebuild their lives. Sepsis Sepsis can happen to anyone, at any age, and recognising the warning signs quickly can make all the difference. As we mark World Sepsis Day we look at what sepsis really is, how easily it can develop, the signs we should never ignore, and what happens after survival. Guests: Deborah Garvie - Policy Manager at Shelter, the housing and homelessness charity. Jez Bushnell's - Salvation Army Policy Analyst leading on Homelessness. Jenny Travassos - Director of Strategy, at The Passage, a charity supporting people experiencing homelessness. Dr. Tom Hellyer - Senior Clinical Fellow & Honorary Consultant in Intensive Care Medicine Dr. Ron Daniels - Intensive Care Consultant in the NHS in Birmingham, Founder and Chief Medical Officer of UK Sepsis Trust, and Vice President of the Global Sepsis Alliance. Caitlyn Sophie - Sepsis Survivor Stephen Moore - CEO of Sepsis Research Team Producers: Durr-e-sameen Mirza and Mahira Ramzeen

This year, ESICM is proud to mark World Sepsis Day with a special podcast, "From Awareness to Action," featuring ESICM President Jan De Waele in conversation with Krista Bracke, sepsis survivor and advocate behind the initiative Sepsis Stronger Together. Together, they discuss what survival really costs, where the gaps between evidence and practice remain, what the new 2026 SSC Guidelines mean for the bedside, and how the clinical and patient communities can work together to drive meaningful change — from education and workforce investment to European policy and national sepsis plans.

AI can help clinicians identify patients at risk of sepsis earlier by analyzing patient data and supporting faster, more informed treatment decisions, says Dr. Bobby Reddy Jr., cofounder and CEO of Prenosis.

Episode Notes In this episode of the DASON Digest podcast, DASON Clinical Pharmacist Liaison, Dr. Melissa Johnson, chats with Dr. Sara Cosgrove about the IDSA/ACEP/ASM/PIDS/SCCM/SHEA/SHM/SIDP Multi-society position paper: “Hospital Strategies to Improve Sepsis Outcomes.” Be sure to check out the companion checklist and article for today's episode. The article reviewed in today's episode can be found here: https://pubmed.ncbi.nlm.nih.gov/42640090/ For more information about DASON, please visit: https://dason.medicine.duke.edu/

Dr. Eckart von Hirschhausen hat seine Doktorarbeit über Sepsis – die bakterielle Blutvergiftung – geschrieben. Zum Weltsepsistag am 13.9. macht er auf das Thema aufmerksam und klärt über die oft unterschätzte Gefahr einer Sepsis auf. Von Eckart von Hirschhausen.

CDI, coding, and clinical medicine are involved in a tug-of-war over a complex, life-threatening medical emergency that seems resistant to all forms of consensus. I'm talking about sepsis of course, and on today's show I got to talk about sepsis with someone as qualified as anyone in the world to do so. Steven Simpson, MD, is Professor of Medicine at the University of Kansas in the Division of Pulmonary, Critical Care, and Sleep Medicine. He has done research in all areas of severe sepsis, from molecular and cellular mechanisms to translational and quality improvement studies. He is currently chair of the board of directors for the Sepsis Alliance and an author of the 2016, 2021, and 2025 reviews and updates of the Surviving Sepsis Campaign Guidelines. I'm also joined by James Kennedy, MD, CCS, a familiar name and voice for anyone involved in CDI and coding circles. Listen in as we cover: Dr. Simpson's deep and rich background in sepsis, including early clinical days with septic patients, working with Drs. Bone and Balk who created Sepsis-1, and his role on the Sepsis Alliance. Co-authoring the 2026 Surviving Sepsis Guideline that defines sepsis as a “life-threatening acute organ dysfunction to infection”: His stance on sepsis-2 and sepsis-3. The politics of definition and diagnosis: Who gets to write these definitions. The struggle: Reconciling sepsis-2 with sepsis-3, further complicated by CMS' use of sepsis-2 in its new sepsis readmission measure. What's the right answer for this, if there is one? Looming sepsis proposal to create codes for “impending sepsis,” the role of AI-technologies (e.g., Sepsis ImmunoScore, TriVerity) in identifying these patients, and what the University of Kansas is doing to identify and intervene on infected patients before they evolve into organ dysfunctions. Plans for future work for other sepsis-related concepts, payers and denials, and a pair of songs for the Off the Record Spotify playlist.

This clip comes from Dr. Raj's series with My Care Friends. Watch the video here: https://www.youtube.com/watch?v=qDFdDI_gZxA About Dr. Raj Dr. Raj Dasgupta is an ABIM Quadruple board-certified physician specializing in internal medicine, pulmonology, critical care, and sleep medicine. He is currently the Associate Program Director of Internal Medicine Residency at Huntington Health in Pasadena, California and an Associate Professor of Clinical Medicine for the University of California, Riverside School of Medicine (UCR). He previously practiced at the University of Southern California, where he is an associate professor of clinical medicine, assistant program director of the Internal Medicine Residency Program, and the associate program director of the Sleep Medicine Fellowship. Dr. Dasgupta is an active clinical researcher and has been teaching around the world for more than 20 years. More from Dr. Raj ⁠⁠⁠⁠The Dr. Raj Podcast⁠⁠⁠⁠ ⁠⁠⁠⁠Dr. Raj on Twitter⁠⁠⁠⁠ ⁠⁠⁠⁠Dr. Raj on Instagram⁠⁠⁠⁠ Want more board review content? ⁠⁠⁠⁠USMLE Step 1 Ad-Free Bundle⁠⁠⁠⁠ ⁠⁠⁠⁠Crush Step 1⁠⁠⁠⁠ ⁠⁠⁠⁠Step 2 Secrets⁠⁠⁠⁠ ⁠⁠⁠⁠Beyond the Pearls⁠⁠⁠⁠ ⁠⁠⁠⁠The Dr. Raj Podcast⁠⁠⁠⁠ ⁠⁠⁠⁠Beyond the Pearls Premium⁠⁠⁠⁠ ⁠⁠⁠⁠USMLE Step 3 Review⁠⁠⁠⁠ ⁠⁠⁠⁠MedPrepTGo Step 1 Questions⁠⁠⁠⁠ ⁠⁠⁠⁠MedPrepTGo Step 2 Questions⁠⁠⁠⁠ Follow MedPrepToGo ⁠⁠⁠⁠https://medpreptogo.com⁠⁠⁠⁠ ⁠⁠⁠⁠https://www.instagram.com/medpreptogo/⁠⁠⁠⁠ ⁠⁠⁠⁠https://www.linkedin.com/company/medpreptogo/⁠⁠⁠⁠ ⁠⁠⁠⁠https://www.facebook.com/MedPrepToGo/⁠⁠⁠⁠ ⁠⁠⁠⁠https://www.youtube.com/@MedPrepToGo⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Worried a small infection could suddenly become sepsis? Melinda Mattox, RN, SCRN, CPHQ, Quality Improvement Coordinator at Riverside Healthcare, explains how routine infections like pneumonia, urinary tract infections, or cuts can sometimes trigger a dangerous, body-wide immune response. Listeners will better understand the immune dysregulation behind sepsis, why prompt treatment of infections matters, the role of wound care and primary care, and why Sepsis Awareness Month emphasizes early recognition.

Presenter Becky Green lost one of her twins to sepsis in 2018. It is a condition that, according to the World Health Organization, is implicated in one in five deaths worldwide - more than bowel, prostate and lung cancer combined. Sepsis can begin as a simple infection and escalate within hours, overwhelming the body and causing organ failure. It is a race against time that too often goes unrecognised until it is too late. But around the world, that is starting to change. Becky speaks to Dr Kissoon of the Global Sepsis Alliance about how our understanding of sepsis has changed. In Malawi and Uganda, she meets the team behind the APT Sepsis programme. By educating healthcare workers on hand hygiene, infection prevention and early detection they have cut maternal deaths and severe infections from sepsis by 32%. In Madrid, Dr Rosa Mendez explains how a hospital-wide "sepsis code" - mirroring fast-track protocols for heart attacks and strokes - has brought sepsis mortality down from 24% to 17%. This episode of The Documentary, comes to you from People Fixing the World, looking at people and projects trying to make the world a better place.

Late sepsis is early to diagnose but catching the early signs is more critical. Don't miss these clinical pearls on inflammatory markers and much more.

What if transforming sepsis requires us to see beyond the disease—and see one another? In this special WFPICCS–PCICS collaboration, renowned sepsis expert Professor Niranjan “Tex” Kissoon shares his vision for transforming sepsis care through education, advocacy, health systems, poverty reduction, access, and post-sepsis support. A powerful conversation about sepsis, vulnerability, and what becomes possible when we meet a global health crisis with science, systems thinking, and our shared humanity. Dr. Kisson is a Professor in the Department of Pediatrics (Pediatrics and Surgery, Emergency Medicine) at the University of British Columbia in Vancouver, BC. Dr. Kissoon is the Past President of the WFPICCS and currently serves as President of the Global Sepsis Alliance. He is Co-Chair of the Pediatric Surviving Sepsis Campaign and Vice-President of the Canadian Sepsis Foundation. He also serves on the Advisory Boards of Sepsis Alliance USA and the African Sepsis Alliance, and he is the Chair of World Sepsis Day and the International Pediatric Sepsis Initiative. He is also a Founding Member of the Caribbean Sepsis Alliance. Co-Host: Deanna Todd Tzanetos, MD, MSCI (Norton Children's/U of Louisville) Host/Editor/Producer: Saidie Rodriguez, MD (CHOA/Emory) To get involved with Global Sepsis Alliance please visit https://globalsepsisalliance.org/ To get involved with WFPICSS please visit https://wfpiccs.org/

About this episode:   Global infant mortality has fallen dramatically since 1990, but neonatal sepsis—a serious bloodstream infection occurring in newborns—still accounts for a significant portion of preventable deaths. Simple interventions like good hygiene practices and sufficient staffing in delivery rooms could reduce infections and prevent fatalities. In this episode: Pablo Duran, a perinatal health expert with the Pan American Health Organization, explains how providers, parents, and public health can prevent, recognize, and treat neonatal sepsis early on for better outcomes. Guest:  Dr. Pablo Duran, PhD, MPH, is a pediatrician and neonatologist who serves as the regional advisor on perinatal health for the Pan American Health Organization. Host:  Dr. Josh Sharfstein is distinguished professor of the practice in Health Policy and Management, a pediatrician, and former secretary of Maryland's Health Department. He served as the Baltimore City Commissioner of Health from 2005 to 2009. Show links and related content:  A Simple Action, a Major Impact: Hand Hygiene Against Maternal and Neonatal Sepsis—Pan American Health Organization Strategies to prevent, detect, and treat neonatal sepsis in the face of AMR—PAHO TV via YouTube Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @‌PublicHealthPod on Bluesky @‌PublicHealthPod on Instagram @‌JohnsHopkinsSPH on Facebook @‌PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.

In children with septic shock, does the choice between balanced crystalloids and 0.9% saline actually matter? This episode reviews the composition and physiologic differences between commonly used crystalloids, summarizes the 2026 PRoMPT BOLUS trial, and discusses how its findings fit with the updated Surviving Sepsis Campaign pediatric guidelines. We also consider the trial's limitations and what the results mean for fluid selection at the bedside. Learning Objectives By the end of this episode, listeners should be able to: Compare the composition and physiologic effects of 0.9% saline and balanced crystalloids used for pediatric fluid resuscitation. Summarize the design and major findings of the PRoMPT BOLUS trial. Describe important limitations of PRoMPT BOLUS when applying its results to children with septic shock. Apply current evidence and 2026 Surviving Sepsis Campaign recommendations when selecting crystalloid fluids for pediatric septic shock. References Weiss SL, Peters MJ, Oczkowski SJW, et al. Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026. Pediatr Crit Care Med. 2026. Published April 1, 2026. Jointly issued by the Society of Critical Care Medicine and Infectious Diseases Society of America. Recommendation 24 suggests balanced/buffered crystalloids over 0.9% saline for children with septic shock requiring fluid boluses (conditional recommendation, very low certainty), while recognizing 0.9% saline as a suitable alternative and preferred in selected situations such as hyponatremia or concern for increased intracranial pressure. Balamuth F, Weiss SL, Long E, et al. Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock. N Engl J Med. 2026. Published April 24, 2026. PRoMPT BOLUS was a large pragmatic randomized trial comparing balanced crystalloids with 0.9% saline in children treated for suspected septic shock and found no reduction in major adverse kidney events within 30 days with balanced fluids. Transcript This transcript was generated using Descript and subsequently reviewed and lightly edited for spelling, grammar, and clarity. Minor inaccuracies may remain, and the audio recording should be considered the definitive version of this content. Welcome to PEM Currents: The Pediatric Emergency Medicine Podcast. As always, I'm your host, Brad Sobolewski, and today we're gonna talk about which fluid we should use when managing a septic pediatric patient. So when we resuscitate a child with septic shock, the major decision is usually not whether to give crystalloid, but which crystalloid to give. And for a long time, there's been a gradual shift towards balanced fluids such as Lactated Ringer's or Plasma-Lyte, largely because they are more physiologic and produce less hyperchloremia than normal saline. The question's always been whether those biochemical differences actually translate into better clinical outcomes. That is the question that a study called PRoMPT BOLUS was designed to answer. So before getting into the trial, it's worth briefly reviewing what these fluids actually contain. So normal saline is 0.9% sodium chloride. It contains one hundred and fifty-four milliequivalents per liter of sodium and a hundred and fifty-four milliequivalents per liter of chloride. The chloride concentration is substantially higher than plasma. Balanced crystalloids contain less chloride and have some other electrolytes and a buffer. Lactated Ringer's contains approximately a hundred and thirty milliequivalents per liter of sodium, one hundred and nine of chloride, four of potassium, a small amount of calcium, and lactate as a buffer. Plasma-Lyte contains approximately one hundred and forty of sodium, ninety-eight of chloride, five of potassium, magnesium, and acetate and gluconate as buffers. The concern with normal saline is that the large chloride loads can produce hyperchloremic metabolic acidosis. There's also been concern about adverse effects on renal blood flow and kidney function. Balanced fluids are designed to more closely approximate plasma composition, so the hypothesis has been that they might reduce kidney injury. That hypothesis has been supported by physiologic data and by some adult studies, although pediatric evidence before PRoMPT BOLUS was limited and inconsistent. The 2026 Surviving Sepsis Campaign Pediatric Guidelines recommend crystalloids over albumin for initial resuscitation and conditionally suggest balanced or buffered crystalloids over 0.9% saline in children with septic shock who require fluid boluses. Importantly, that recommendation is based on very low-certainty evidence. Balanced options again include Lactated Ringer's, Hartmann's solution, or Plasma-Lyte. If balanced fluids are not readily available, saline remains an acceptable alternative. Saline may also be preferable in some specific situations like significant hyponatremia or concern for increased intracranial pressure. For children in resource-abundant settings, the general approach is still ten to twenty mLs per kilo per bolus with reassessment after each bolus, potentially up to forty to sixty mLs per kilo in the first hour if perfusion remains abnormal and there are no signs of fluid overload. Now, PRoMPT BOLUS, the full name of which is the Pragmatic Pediatric Trial of Balanced versus Normal Saline Fluid in Sepsis, was an international randomized pragmatic trial designed to specifically compare the two fluid strategies in children with suspected septic shock. The final trial enrolled nine thousand and forty-one children from two months to younger than eighteen years across forty-seven emergency departments in five countries. Children were randomized to predominantly balanced crystalloid or predominantly 0.9% saline, and the assigned fluid strategy was used for bolus and maintenance crystalloid during the initial treatment period. The balanced fluid arm was not a single product. Depending on the site, children could get Lactated Ringer's, Hartmann's solution, or Plasma-Lyte. That's important when interpreting the study. PRoMPT BOLUS was really testing a strategy of predominantly balanced crystalloid versus a strategy of predominantly saline use rather than comparing LR versus saline alone, though LR was the most commonly used one. The primary outcome was something called MAKE30, M-A-K-E thirty, or major adverse kidney events within thirty days. This was a composite outcome that included death, new renal replacement therapy, or persistent kidney dysfunction. That choice of outcome is useful because the biologic rationale for balanced fluids has always centered largely on kidney protection. The investigators were therefore asking whether the lower chloride exposure associated with balanced fluids translated into clinically meaningful renal benefit. So what was the result? Well, the spoiler is that the answer was no. So MAKE30 occurred in three point four percent of children receiving balanced fluids and three percent receiving saline. The relative risk was one point one with a ninety-five percent confidence interval from point eight eight to one point four. There were also no significant differences in death, new renal replacement therapy, persistent kidney dysfunction, or hospital-free days. In practical terms, balanced crystalloids did not improve the major patient-centered outcomes the trial was designed to measure. There were clear biochemical differences between the groups. Hyperchloremia occurred in thirty-one point four percent of children receiving balanced fluids compared with forty-nine percent with saline. Hypernatremia was also less common with balanced fluids, one point eight versus three point one percent. Hyperlactatemia was slightly more common in the balanced fluid group, nineteen point eight compared with sixteen point seven percent. So the fluids behaved differently in the ways that you would expect physiologically. Balanced crystalloids clearly reduced hyperchloremia, but that difference did not translate into fewer major kidney events, less dialysis, shorter hospitalization, or lower mortality. There are several limitations to this study worth keeping in mind. The first is that this was a broad emergency department population with suspected septic shock, not a study limited to children with the most severe forms of shock. Only a minority of patients required vasoactive medications, and overall mortality was low. The results are therefore most applicable to the typical child with suspected septic shock receiving early ED resuscitation. They do not completely answer whether fluid composition might matter more in a smaller subgroup of children receiving very large fluid volumes or prolonged resuscitation. The second limitation is that the event rate for MAKE30 was lower than expected. When the trial was designed, investigators anticipated an event rate of about six percent in the saline group. The observed rate was closer to three percent. That means there were fewer outcome events than anticipated, which reduced the ability to detect a very small treatment effect. So the trial makes a large benefit from balanced fluids unlikely, but it can't exclude a small or subtle difference. A third limitation is that the balanced fluid group included several different solutions. Lactated Ringer's, Plasma-Lyte, and Hartmann's are all considered under the umbrella of balanced crystalloids, but they're not chemically identical. The study therefore supports the broader conclusion that a balanced fluid strategy is not superior to saline for most children in this setting, rather than providing equivalence between any single specific balanced solution and saline, even though Lactated Ringer's is used far and away most often. The trial was also intentionally pragmatic, which means that there was some crossover between fluid types. Adherence was defined as receiving at least seventy-five percent of crystalloid as the assigned fluid rather than requiring exclusive use of one fluid. That could reduce the ability to detect a small treatment effect, but it also makes the study more reflective of real clinical practice. The investigators themselves described the trial as a comparison of predominant rather than exclusive use of balanced crystalloids versus saline. Finally, the trial was open label, so clinicians knew which fluid the child was receiving. That introduces the possibility of treatment bias, though the primary outcome relied on relatively objective measures. A substantial proportion of children also did not have a measured baseline creatinine, so baseline kidney function sometimes had to be imputed using age- and sex-based values. That's worth remembering because persistent kidney dysfunction was part of the primary composite outcome. Taken together, I think PRoMPT BOLUS makes the bedside decision simpler. Balanced fluids remain a completely reasonable and defensible choice. They cause less hyperchloremia, and there's no reason to abandon them if they're already part of your usual resuscitation fluid strategy or your order sets. At the same time, the largest pediatric randomized trial now shows no improvement in major kidney or mortality outcomes compared with normal saline. So if you use saline at your local hospital, that's okay too. The 2026 Surviving Sepsis Campaign still conditionally favors balanced crystalloids, but that recommendation is based on very low-certainty evidence. So PRoMPT BOLUS adds important randomized data suggesting that for most children with septic shock, either crystalloid strategy is reasonable. The practical takeaway is that the choice of crystalloid is probably less important than getting the resuscitation itself right. Give 10 to 20 mLs per kilo when a fluid bolus is indicated, reassess frequently, watch for improvement in perfusion and for signs of fluid overload, and move to vasoactive support when fluid alone is not correcting the shock. Balanced crystalloids will produce less hyperchloremia. Normal saline will produce more. In PRoMPT BOLUS, that biochemical difference did not translate into a difference in kidney injury, dialysis, or mortality. For most children with septic shock, balanced fluids are fine, normal saline is fine, and timely, thoughtful resuscitation matters much more than which bag is hanging. I hope you found this episode on fluids for sepsis in children helpful and that you'll be able to take this knowledge back to the bedside the next time you work in the emergency department. If you've got other topics you want me to cover, especially as they relate to practice-changing research in pediatrics, like the PRoMPT BOLUS trial from the Pediatric Emergency Care Applied Research Network, PECARN as we call it, let me know. Send it my way. If you have time to leave a review on your favorite podcast site, please do so. It helps other people find the show, and definitely share this with your colleagues. I think this study and perhaps this podcast episode could be a great combo for an upcoming journal club. For PEM Currents, the Pediatric Emergency Medicine Podcast, this has been Brad Sobolewski. See you next time.  

The Center for Disease Control and Prevention (CDC) along with the National Center for Health Statistics (NCHS) jointly announced the agenda of its September 15-16, 2026, Coordination and Maintenance committee meeting.During the live event, the public can view and provide feedback on proposed amendments to the International Classification of Diseases, 10th Edition (ICD-10), Clinical Modification (CM), and the HIPPA-sanctioned diagnosis reporting convention required on most provider claims.Among the challenging subjects expected to be presented during the two-day meeting, include whether ICD-10-CM should transition from Sepsis-2 to Sepsis-3 terminology, amending heart failure terminology to coincide with the Second Universal Definition of Heart Failure, and whether to apply the Society for Cardiovascular Angiography & Interventions (SCAI) staging classification (A, B, C, D, and E) for cardiogenic shock, and other topics submitted by the public.During the live edition of the popular Internet broadcast, Talk Ten Tuesday, James S. Kennedy, MD, president of CDIMD, will provide his perspective on identifying proposals and outline how the public can participate in a meaningful way.The popular weekly Internet broadcast will also feature these additional instantly recognizable panelists, who will report more news during their segments:• POV: Penny Jefferson, Manager of Coding & Clinical Documentation Integrity Services for the University of California-Davis Medical Center, will share her point of view during the broadcast.• CDI Report: Cheryl Ericson will provide an update on all things clinical documentation integrity (CDI).• SDoH Report: Tiffany Ferguson will report on news happening at the intersection of compliance and medical record coding.• The Coding Report: Christine Geiger will report on the latest coding news.• Talk Ten Tuesday News Desk: Timothy Powell, deliver the latest news from the Talk Ten Tuesday News Desk.

I break down what “doctor-side” AI actually looks like in real clinics and hospitals, from note-writing tools to radiology triage and sepsis alerts. The throughline is simple: AI helps most when it removes administrative drag and a human consistently reviews what it produces before it affects you.• Ambient scribes that record visits and draft clinical notes while restoring face-to-face attention• Documentation time savings and what the early research shows for physician burnout and patient experience• AI-drafted patient portal replies and the “portal paradox” that can create extra editing work• Radiology AI that flags urgent findings and reprioritizes scans rather than replacing radiologists• Mammography and pathology examples where AI acts as a second reader• Algorithmic bias risks when training data does not reflect all patients• Sepsis prediction tools that can save lives but vary widely by validation and implementation• Medication safety alerts, high override rates, and alert fatigue• Prior authorization “robot war” dynamics and why appeals are a growing AI use case• Liability questions and new state-level moves requiring human review and AI disclosure• Practical patient tips for asking about recording, AI lookups, and how scan flags are usedTo catch up on more episodes and to get new ones delivered directly to you, subscribe wherever you find your podcasts. Apple, Google, Spotify, iHeartRadio, and more. If you'd like to be a guest or have an idea for an episode, let me know at www.drpatientpodcast.com. That's doctorpatientpodcast.com.

In today's VETgirl online veterinary continuing education podcast, we're talking about the new veterinary sepsis definitions. Having clear definitions is crucial in making sure we're talking about the same type and severity of disease. Until now, our veterinary sepsis definitions have been largely adapted from human medicine. But let's be honest, our patients who have a talent for hiding illness don't always follow the same rules as humans. Having veterinary-specific definitions gives researchers a more consistent way to compare patients and studies, while giving clinicians a stronger foundation for recognizing sepsis, assessing illness severity, and shaping both today and tomorrow’s treatment recommendations.

LISTENER DISCRETION IS ADVISED! References: Alam N, Oskam E, et. al. PHANTASi Trial Investigators and the ORCA (Onderzoeks Consortium Acute Geneeskunde) Research Consortium the Netherlands. Prehospital antibiotics in the ambulance for sepsis: a multicentre, open label, randomised trial. Lancet Respir Med. 2018 Jan;6(1):40-50. Jouffroy, R., Annane, D., et. al. (2026). A 1-hour resuscitation bundle for prehospital management of septic shock. Critical Care Medicine. Knack, S. K. S., Scott, N., Driver, B. E., et al. (2024). Early physician gestalt versus usual screening tools for the prediction of sepsis in critically ill emergency patients. Annals of Emergency Medicine. Kotnarin R, Sirinawee P, Supasaovapak J. Impact of Prehospital Antibiotics on in-Hospital Mortality in Emergency Medical Service Patients with Sepsis. Open Access Emerg Med. 2023 May 26;15:199-206. Poynter, M. J., Farrugia, A., Kelly, E., & Simpson, P. M. (2023). Prehospital administration of antibiotics in addition to usual care versus usual care alone for patients with suspected sepsis – A systematic review. Paramedicine, 21, 52–65. Scales DC, et. al. Prehospital antibiotics and intravenous fluids for patients with sepsis: protocol for a 2×2 factorial randomised controlled trial. BMJ Open. 2025 May 27;15(5):e104257.

More insight into the Perez situation and a statement from his sister. Plus find out about Cindy Crawfod's daughter's fight with the devil. That's right. Stefanie sneaks in a new Howard Stern story!

Show notes at pharmacyjoe.com/episode1157 In this episode, I'll discuss differences in heart rate in patients with sepsis and AFib between phenylephrine and norepineprhine.

Hallie C. Prescott, MD, MSc, joins CHEST® Journal Podcast Moderator Alice Gallo De Moraes, MD, FCCP, to discuss her research into the impact of timely antibiotic delivery and fluid resuscitation on discharge to home after sepsis. DOI: 10.1016/j.chest.2026.03.002 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.  

In today's episode of Backpacker Radio presented by The Trek, brought to you by Topo Athletic, we are joined by Shawn Mahoney, aka the guy who carries a 20+ pound log named Larry over his shoulders, and with Larry he's hiked the Triple Crowner, Te Araroa, and just about all of the Northeast peaks. In this one, Shawn explains why the heck he carries a massive log everywhere he goes, describes losing Larry down a steep slope  on the PCT and spending two hours bushwhacking to retrieve him, recounts nearly dying from a septic heart infection and medically induced coma- and the impact that's had on his passion for backpacking, and details how he waking up at 4am, or earlier, to bank miles pre-sunrise. We also cover how he's raised several thousand dollars for charity, how you can contribute to his latest cause, his refusal to cook or cold-soak, and his party trick of solving a 9x9 rubik's cube while hiking, something he accomplishes mid interview. We wrap the show with Trek Propaganda of Kelly's favorite thru-hiking memories, a heroic dog intimidating a black bear to save a kid's life - maybe, a trail debate on losing your spoon vs. your shelter, the Triple Crown of movies everyone loves but you hate, and I review the uber-popular FarPointe Sun Hoodie but you'll probably have to wait til Thursday for that one so kinda nevermind. Topo Athletic: Use code "TREK15HIKE" at topoathletic.com. Gossamer Gear: Use code "BACKPACKERRADIO" for $20 off LT5 Trekking Poles at gossamergear.com.  Hyperlite Mountain Gear: Use code "BPRADIO15" for 15% of hyperlitemountaingear.com [divider] Interview with Shawn Mahoney and Larry the Log Shawn's Instagram Time stamps & Questions 00:05:40 - Reminders: Join us for a hiker meetup in Seattle, apply to vlog or blog for the Trek, listen to our episodes ad-free on Patreon! 00:10:30 - Introducing Shawn and Larry 00:12:30 - Why does Larry exist? 00:15:40 - How many times do you switch positions of the log over a day? 00:18:12 - Do you feel relief or separation anxiety when you put the log down? 00:20:11 - What branch of the military did you serve in, and how did you go from post-military training to hiking the AT with a log? 00:24:06 - Why a log instead of a weighted vest or rucksack? 00:27:07 - How do you get the log ready to be carried? What's the prep and sanding process? 00:29:32 - Have you thought about giving each log a unique name beyond "Larry"? 00:33:43 - What's it like navigating the AT bubble with a wide log — close calls with day hikers? 00:35:52 - What are all the charities you've raised money for, and how much in total? 00:40:45 - Discussion about the speed of hiking the AT 00:42:20 - Tell us about the septic heart infection and the 50/50 survival odds 00:47:30 - What was your mindset recovering from sepsis, and how did exercise become your outlet? 00:48:50 - What is your typical hiking style? 00:52:31 - Was there a moment where you had to reframe your identity from "not athletic" to what you are now? 00:54:14 - What do you do for work, and how do you afford to disappear for months at a time? 01:01:24 - You're headed to the Colorado Trail — what's the plan this time around? 01:03:10 - Have you ever done a thru-hike at a leisurely pace? 01:06:14 - What was Te Araroa like — especially navigating mud and terrain with a giant log? 01:10:15 - Are you ever in a gym, or is all your training done outside with the log? 01:11:01 - Do you have to be mindful about nutrition carrying 27 extra pounds all day? 01:15:34 - What is your base weight, and what's actually in the pack? 01:19:00 - What does Rubik's Cube problem-solving actually correlate to? 01:21:30 - Is there anything else you want to relay to listeners, and where can people find you? 01:22:05 - Peak Performance Question: What is your top performance enhancing or backpacking hack? Segments Trek Propaganda:  Turkenna Saw a Black Bear by The Norris Trio Before You Read Another Thru-Hiking Horror Story, Read This by Kelly Floro QOTD: Would you rather, on day 1 of your thru-hike, lose your shelter and have to always cowboy camp on the AT, or lose your spoon and have to eat all meals with only your hands? Triple Crown of movies everyone loves but you hate Mail Bag 5 Star Review [divider] Check out our sound guy @my_boy_pauly/ and his coffee. Sign up for the Trek's newsletter Leave us a voicemail! Subscribe to this podcast on iTunes (and please leave us a review)!  Find us on Spotify, Stitcher, and Google Play. Support us on Patreon to get bonus content. Advertise on Backpacker Radio Follow The Trek, Chaunce, Badger, and Trail Correspondents on Instagram. Follow Backpacker Radio, The Trek and Chaunce on YouTube. Follow Backpacker Radio on Tik Tok.  Our theme song is Walking Slow by Animal Years. A super big thank you to our Bob Peoples Award winner(s) from Patreon: Alex and Misty with NavigatorsCrafting, Alex Kindle, Austen McDaniel, Bill Jensen, Bret Mullins aka Cruizy, Bryan Alsop, Carl Lobstah Houde, Christopher Marshburn, Coach from Marion Outdoors, Eric Casper, Erik Hofmann, Ethan Harwell, Gillian Daniels, Greg Knight, Greg Martin, Griffin Haywood, Hailey Buckingham, Jackson Storm, JaredNotFromSubway, Jason Kiser, Jason "I Miss Chaunce" Snailer, Luke Netjes, Matty in AZ, Patrick Cianciolo, Randy Sutherland, Rebecca Brave, Rural Juror, Sawyer Products, The Saint Louis Shaman, Thirteen Adventures, Timothy Hahn, Tracy 'Trigger' Fawns A big thank you to our Cinnamon Connection Champions from Patreon: Bells, Benjy Lowry, Bonnie Ack, Brett Vandiver, Chris Pyle, David Neal, Dcnerdlet, Denise Krekeler, Jack Greene, Jeanie, Jeanne Latshaw, Lucas Hamilton, Merle Watkins, Peter, Quenten Jones, Ruth S, Salt Stain, Sloan Alberhasky, and Tyler Powers.

This month for the July 2026 episode of the RCEMLearning Podcast Becky and Chris talk through the second in a two parter on the Surviving Sepsis Campaign Guidelines update. Rob then speaks with Arya Rao about LLMs and clinical reasoning. If you'd like to email us, please feel free to do so here. After listening, complete a short quiz to have your time accredited for CPD at the RCEMLearning website! (02:13) Guidelines for EM - Surviving Sepsis Campaign Guideline (Part 2 of 2) Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 (22:50) Arya Rao - LLMs and Clinical Reasoning Large Language Model Performance and Clinical Reasoning Tasks (Rao et al., 2026)

Dr Janet Pope: QD Clinic: Can RA and Gout Manifest Simultaneously?  Dr. Mrinalini Dey QD312: Gout, Sepsis… or Both?  Daric Mueller, PA-C QD315: Pegloticase Immunomodulation: What's on the Menu?  Dr. Richard Conway: QD313: Don't Presume on IL-1 in Gout 

When experts are already there, they still may not see:"I think we need to go get our own data.""Sepsis smelled differently to him.""The more you dig into the individual, the more people you affect."One patient can teach what a system keeps missing...See BoldEncounters.TVA Table Turners SeriesAngela Finlay turns the tables again in Part 3.What If You Already Work in the Customer Space?Part 3 asks the harder question: what if you already work where the need happens, but still do not see it clearly? Mark brings in Dr. Todd Allen, whose sepsis work shows how doctors, nurses, phlebotomists, data, simulation, and direct observation helped move severe sepsis from a one-in-two mortality reality toward one-in-ten outcomes.Step Back and Look through New LensesBold Immersion is not only going somewhere new. Sometimes it means stepping back inside your own workplace with a fresh lens, watching one person at a time, and letting the senses find patterns that meetings, dashboards, and authority miss. Here, observation becomes more than a business tactic. It becomes a way to save lives, redesign care, serve customers, and build evidence no one can dismiss.Inside This Episode• Why ER doctors still needed a new lens inside the ER.• How a phlebotomist smelled signs in sepsis innovation.• Why studying one patient can help a system affect many.• How authoritative thinking delays care and needs to loosen.• What hospital rooms, produce pricing, and pediatric MRIs reveal about going to the scene.Go Deeper — Premium Action PlanThis Table Turners series culminates in a club-only Premium Action Plan led by Mark. Start now by choosing one familiar workflow you think you already understand. Watch it again as if new: who waits, who repeats work, who has hidden knowledge, what gets delayed, and what one person reveals about the whole system.Listen + Connecthttps://www.BoldEncounters.TVAngela Finlay, Table Turnerhttps://www.windwardhcm.comhttps://www.linkedin.com/in/ablumfinlay/Todd Allen, MDtodd.allen.ut@gmail.comlinkedin.com/in/todd-l-allen-md-facep-a8a7779Mark S. Cookhttps://www.WindfallPartners.comMoments To Revisit• Dr. Todd Allen explaining why a computer solution failed four times.• The phlebotomist whose senses caught what the system needed.• Mark connecting individual observation to larger population impact.• The hospital-ceiling video that made boredom impossible to ignore.• Dina Peters putting 400 hours a month back into produce service.Final ThoughtMark reveals that being near the work is not the same as seeing it. Real advantage comes when a professional steps back, gathers firsthand data, honors hidden expertise, and runs toward the space of the problem with enough humility to be changed by what is actually there.Join Us!Watch Part 3, then continue into the detailed examples and Premium Action Plan at https://www.BoldEncounters.TVThank YouDr. Terry Clemmer and Dr. Todd Allen, sepsis improvement and emergency-medicine observation.IDEO and Diego Rodriguez, hospital-room and pediatric MRI observation.Thomas Franklin, 9/11 photojournalism proximity.Dina Peters, produce pricing and service-hours example.Subaru of Indiana Automotive, zero-landfill preview.Calvin Cook—Caljo, original music, @Caljo MusicSacha Arias, Post Production, ska.films0211@gmail.comAliyah Peña, Post Production, aliyahmpena@gmail.comSkyler Maudsley, Video Editing, skylermaudsley@gmail.comRosalie McGinn, Social Media, rosalie.mcginn1@gmail.com

Sepsis management has traditionally focused on timely antibiotic treatment, hemodynamic support, and source control, but emerging evidence suggests that outcomes may be shaped long before patients reach the ICU. In this episode of the Society of Critical Care Medicine (SCCM) Podcast, host Diane C. McLaughlin, DNP, AGACNP-BC, CCRN, FCCM, speaks with Sayed Abdulmotaleb Almoosawy, MBChB (Hons), about his article “The Association Between Socioeconomic Position and Mortality in Patients With Sepsis and Septic Shock—A Systematic Review and Meta-Analysis,” published in the April 2026 issue of Critical Care Medicine. Drawing on 13 observational studies that encompassed nearly 4 million patients, the analysis evaluates how factors such as insurance status, income, education, and neighborhood deprivation relate to short-term mortality outcomes. The findings reveal a consistent association between lower socioeconomic position and increased mortality, with lack of private insurance demonstrating the strongest signal—likely reflecting barriers to timely access to care and delayed presentation. This episode challenges clinicians and researchers alike to recognize the link between socioeconomic disadvantages and worse sepsis outcomes, highlighting the need to collect equity-relevant data and reduce gaps in care to improve survival for critically ill patients. Resources referenced in this episode: Almoosawy SA, Fernando SM, Rochwerg B, et al. The association between socioeconomic position and mortality in patients with sepsis and septic shock—a systematic review and meta-analysis. Crit Care Med. 2026;54(4):692-700. Prescott HC, Antonelli M, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026. Crit Care Med. 2026;54(4):725-812.

This episode features Professor Bram Rochwerg discussing the latest guidelines on surviving sepsis, covering evidence-based practices, fluid management, vasopressor use, and emerging therapies. Gain insights into how expert panels synthesize evidence to guide critical care in sepsis management.Key Topics Covered: Sepsis guideline updates 2026Evidence synthesis and recommendation strengthFluid resuscitation strategies and targetsVasopressor use and peripheral administrationEmerging therapies: Methylene blue, steroids, bicarbonateBiomarkers and diagnostics in sepsisLinks: Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 | SCCMExecutive Summary: Surviving Sepsis Campaign:... : Critical Care Medicine

Show notes at pharmacyjoe.com/episode1149 In this episode, I'll discuss the impact of pharmacist involvement on hospital sepsis response teams.

Fred Turner is the Founder and CEO @ Curative, one of the wildest stories in tech. Fred scaled a COVID testing business from $0 to $5BN in revenue and took the team from 7 to 7,000 employees in just 9 months. They did over 206,000 COVID tests in a single day and signed contracts in the 100s of $Ms with several of the largest states. Today, Curative is a unicorn health insurance business taking on the incumbents for one of the largest markets in healthcare.  AGENDA: 00:00 How Did a Spare-Time COVID Test Become a $5BN Business? 07:00 How Do You Go From Testing Cows to STDs, Sepsis and COVID? 21:00 When Did Fred Realise COVID Was Massive—and How Did Curative Scale to $5BN? 36:00 Why Pivot Into Health Insurance—and What Is Broken About US Healthcare? 40:00 How Is AI Rebuilding Curative—and Which Departments Go to Zero? 45:00 Is SaaS Dead? Why Is Curative Cutting 80% of Its Software Spend? 48:00 Are Legacy Insurers Screwed? What Will Anthropic Be Worth in Three Years? 59:00 Will AI Make Companies Smaller? Which Jobs Will Survive? 1:10:00 Why Nuclear—and Could Subcritical Become Bigger Than Curative? 1:17:00 What Have Marriage and Fatherhood Taught Fred? What Has He Changed His Mind On?    

Es beginnt harmlos: Der 14-jährige Elia kehrt mit einem leichten Husten aus dem Skilager zurück. Doch sein Zustand verschlechtert sich zunehmend, sodass ihn seine Eltern in die Notaufnahme des Kantonsspitals Baden bringen. Trotz anhaltender Beschwerden wird Elia von den Ärztinnen nach Hause geschickt – zum Unverständnis seiner Eltern. Vier Tage später stirbt er an einem septischen Schock und Multiorganversagen. Gegen mehrere Ärzte des Kantonsspitals läuft inzwischen ein Strafverfahren. Es gilt die Unschuldsvermutung. Dass sich Eltern zu wenig ernst genommen fühlen, war auch in Luzern bereits Thema. Vor einem Jahr starb dort ein einjähriger Bub an einer bakteriellen Infektion, nachdem seine Mutter im Kinderspital vergeblich auf den kritischen Zustand hingewiesen haben soll. Deshalb hat das Kinderspital Luzern als erstes Schweizer Spital «Martha's Rule» eingeführt: Wenn Eltern mit der ärztlichen Einschätzung nicht einverstanden sind, können sie eine unabhängige Zweitmeinung einholen. Was ist im Fall Elia passiert? Was ist «Martha's Rule» genau – und inwiefern kann sie künftig Leben retten? Und bedeutet sie einen Kulturwandel in den Spitälern? Janina Gehrig, Redaktorin im Ressort Leben, hat den Fall von Elia recherchiert, Bundeshausredaktor Markus Brotschi die Hintergründe zu «Martha's Rule». In der neuen Folge des täglichen Podcasts «Apropos» ordnen sie den Fall ein und erklären, wie die Regel die Sicherheit von Patientinnen und Patienten verbessern könnte. Host: Alexandra Aregger Produzentin: Valeria Mazzeo Mehr zu Elias Fall und «Martha's Rule» Teil 1: Der Fall von Elias und wie er an einer nicht erkannten Sepsis starb Teil 2: Der Fall von Elias – wurde der Bericht beschönigt? Martha's Rule: Kinderspital Luzern führt Notknopf für Eltern ein Unser Tagi-Spezialangebot für Podcast-Hörer:innen: tagiabo.chHabt ihr Feedback, Ideen oder Kritik zu «Apropos»? Schreibt uns an podcasts@tamedia.ch Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Sepsis is fast, deadly, and often misdiagnosed — and when hospitals don't listen, parents pay the price.In this powerful episode, Risa shares her family's real-life nightmare after her son, Nicholas, was repeatedly misdiagnosed with a virus while suffering from sepsis. What started as a routine hospital visit turned into a fight for survival, exposing serious flaws in the healthcare system and the devastating consequences of medical negligence.This conversation is a must-listen for parents, caregivers, and anyone navigating the healthcare system. Risa's story is a reminder that parental instincts matter, advocacy saves lives, and accountability in hospitals is long overdue.In this episode, we discuss:How sepsis is commonly misdiagnosed in childrenWhy parents must trust their instincts — even when doctors dismiss concernsWhat really happens inside the ICU during a medical crisisThe emotional toll medical negligence takes on familiesWhy hospital accountability and patient advocacy matterHow awareness and education can prevent future tragediesThis is not just a story — it's a warning, a call to action, and a mission to protect other families.⏱️ Chapters00:00 – A Mother's Nightmare: Nicholas's Sepsis Story02:12 – Life Before the Crisis: A Normal Family03:39 – The Warning Signs Doctors Ignored07:22 – The ER Visit That Changed Everything08:52 – Inside the ICU: Fighting for Survival09:48 – Missed Opportunities and Medical Negligence15:00 – The Ripple Effect: Other Families' Stories16:47 – Systemic Failures in Healthcare19:02 – From Trauma to Advocacy21:35 – Nicholas's Long Road to Recovery27:54 – Life After Sepsis35:42 – Hospital Accountability & Legislative Change44:52 – Finding Strength, Purpose, and Hope

Julie Yoo sits down with Dr. Suchi Saria, founder and CEO of Bayesian Health, to discuss the current state of clinical AI and what it takes to deploy AI systems in real-world healthcare settings. While much of the recent attention around AI has focused on copilots, chatbots, and administrative workflows, Saria argues that the greatest opportunity lies in helping clinicians make better decisions at the point of care. She explains how Bayesian Health's clinical intelligence platform continuously analyzes multimodal patient data to identify signs of deterioration, sepsis, and other high-risk conditions before they become medical emergencies. The conversation explores FDA approval, reimbursement, clinician trust, AI governance, hospital workflows, and why healthcare requires a higher standard of evidence than most software categories. Along the way, Saria shares lessons from bringing AI into clinical practice, the future of proactive medicine, and why the next era of healthcare may be defined by continuous intelligence rather than reactive care.   Resources: Follow Suchi Saria on X: https://x.com/suchisaria Follow Julie Yoo on X: https://x.com/julieyoo   Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

About our Guests: Fran Balamuth, MD, PhD, MSCE, is division chief of Pediatric Emergency Medicine at the Children's Hospital of Philadelphia. Dr. Balamuth's research interests focus on pediatric sepsis recognition using epidemiologic and translational approaches, for which she has received NIH and foundation funding. She is the co-PI of the PROMPT BOLUS trial, a multinational pragmatic trial comparing saline vs balanced fluids in pediatric sepsis, which will be the largest acute care pediatric trial in history. In addition, she co-leads the CHOP Pediatric Sepsis Program, which supports and promotes local clinical, research, educational, and quality-improvement initiatives related to sepsis. She is an internationally recognized sepsis leader, and has been invited to serve on the national steering committee for the Improving Pediatric Sepsis Outcomes quality collaborative through the US Children's Hospital Association, and 2 international task forces focused on defining pediatric sepsis through the US Centers for Disease Control and Prevention and the Society of Critical Care Medicine.Scott L. Weiss, MD, MSCE, FCCM, is a Professor of Pediatrics & Pathology and Genomic Medicine at Thomas Jefferson University and division chief of Critical Care Medicine at Nemours Children's Hospital, Delaware. Previously, Dr. Weiss was on the faculty at the Children's Hospital of Philadelphia, where he earned recognition as an international expert in pediatric sepsis. Dr. Weiss' NIH-funded research focuses on epidemiology, fluid resuscitation, and mitochondrial dysfunction in pediatric sepsis. Dr. Weiss is an international expert in pediatric sepsis and served as the co-PI of the PRoMPT BOLUS trial.Nathan Kuppermann, MD, MPH, is Executive Vice President and Chief Academic Officer of Children's National Hospital and Director of the Children's National Research Institute. He also serves as chair of the Department of Pediatrics and associate dean of Pediatric Academic Affairs at the George Washington University School of Medicine and Health Sciences. He is an internationally recognized clinical trialist in pediatric trauma, pediatric DKA, and acute pediatric infections. As the original chair of the Pediatric Emergency Medicine Applied Research Network (PECARN); his research is focused on clinical trials and clinical prediction rules using large cohorts of acutely ill and injured children. Dr. Kuppermann served as the senior investigator of the PRoMPT BOLUS trial.Selected References:Weiss SL, Balamuth F, Long E, Thompson GC, Hayes KL, Katcoff H, Cook M, Tsemberis E, Hickey CP, Williams A, Williamson-Urquhart S, Borland ML, Dalziel SR, Gelbart B, Freedman SB, Babl FE, Huang J, Kuppermann N; Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis (PRoMPT BOLUS) Investigators of the PECARN, PERC, and PREDICT Networks. PRagMatic Pediatric Trial of Balanced vs nOrmaL Saline FlUid in Sepsis: study protocol for the PRoMPT BOLUS randomized interventional trial. Trials. 2021 Nov 6;22(1):776. doi: 10.1186/s13063-021-05717-4. Erratum in: Trials. 2025 Oct 7;26(1):390. doi: 10.1186/s13063-025-09164-3. PMID: 34742327; PMCID: PMC8572061.Weiss SL, Balamuth F, Thurm CW, Downes KJ, Fitzgerald JC, Laskin BL. Major Adverse Kidney Events in Pediatric Sepsis. Clin J Am Soc Nephrol. 2019 May 7;14(5):664-672. doi: 10.2215/CJN.12201018. Epub 2019 Apr 18. PMID: 31000518; PMCID: PMC6500940.Semler MW, Self WH, Wanderer JP, Ehrenfeld JM, Wang L, Byrne DW, Stollings JL, Kumar AB, Hughes CG, Hernandez A, Guillamondegui OD, May AK, Weavind L, Casey JD, Siew ED, Shaw AD, Bernard GR, Rice TW; SMART Investigators and the Pragmatic Critical Care Research Group. Balanced Crystalloids versus Saline in Critically Ill Adults. N Engl J Med. 2018 Mar 1;378(9):829-839. doi: 10.1056/NEJMoa1711584. Epub 2018 Feb 27. PMID: 29485925; PMCID: PMC5846085.Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & ZacSupport the showHow to support PedsCrit:Please complete our Listener Feedback SurveyPlease rate and review on Spotify and Apple Podcasts!Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com.  You can also check out our website at http://www.pedscrit.com. Thank you for listening to this episode of PedsCrit!

This month for the June 2026 episode of the RCEMLearning Podcast Becky and Chris talk through the first in a two parter on the Surviving Sepsis Campaign Guidelines update. Rob then speaks with Alison Tavare about the NCEPOD learning disability report. If you'd like to email us, please feel free to do so here. After listening, complete a short quiz to have your time accredited for CPD at the RCEMLearning website! (01:56) Guidelines for EM - Surviving Sepsis Campaign Guideline (Part 1 of 2) Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 (27:31) NCEPOD Acute Illness in people with a learning disability - Alison Tavare NCEPOD - Acute illness in people with a learning disability

Just as pneumonia isn't “just a cold,” the pneumococcal vaccine does much more than just protect yourself or your child against pneumonia. Listen in and learn from experts Robert H. Hopkins, Jr., MD, and Brenda L. Tesini, MD, how to discuss the full benefits of pneumococcal vaccine.  Topics covered include: Burden of pneumococcal disease among pediatric and older adult populations in the United States Risk factors for severe pneumococcal disease Which pneumococcal vaccines to use for certain populations and why How pneumococcal vaccination protects from long-term sequelae and potential community benefits of vaccination Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify. Presenters: Robert H. Hopkins, Jr., MD Professor of Internal Medicine and Pediatrics Division of General Internal Medicine University of Arkansas for Medical Sciences, School of Medicine Little Rock, Arkansas Brenda L. Tesini, MD Associate Professor of Medicine, Pediatrics, and Community Health Division of Infectious Diseases University of Rochester Medical Center Rochester, New York Link to program page: https://bit.ly/3SuymiN Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Book a free consultation call with Robert Sikes to break through your keto or low carb plateau here: https://www.ketobodybuilding.com/callA 30 year eating disorder drove her from 70 lbs to 220 lbs, through anorexia, sepsis, and back to healing with carnivore. In episode 894 of the Savage Perspective Podcast, host Robert Sikes sits down with Mary Ann Peters for a raw story of food noise, restriction, weight loss, weight gain, recovery, and faith. Mary Ann shares how childhood shame, years of disordered eating, and not eating enough on carnivore hurt her health, and how changing her nutrition helped her heal. This Savage Perspective Podcast episode covers eating disorder recovery, keto, carnivore, healing, mental health, body image, and learning to eat for strength, peace, and a better life.Follow Mary on IG: https://www.instagram.com/peglegcarnivore/Get Keto Brick: https://www.ketobrick.com/Subscribe to the podcast: https://open.spotify.com/show/42cjJssghqD01bdWBxRYEg?si=1XYKmPXmR4eKw2O9gGCEuQChapters0:00 - Mary Ann Peters' Backstory and How Her Eating Disorder Began6:16 - How a College Breakup Turned Food Into a Coping Mechanism12:23 - From Paleo to Carnivore: What Actually Helped Her Heal?20:16 - How a Hot Tub Infection Led to Sepsis, Organ Failure and Limb Loss30:49 - Learning to Walk Again and Why Her Parents Saw Carnivore as Dangerous37:47 - How Faith, Surrender and a Near-Death Experience Changed Her Perspective44:21 - Why Carnivore Helped Her Mentally and Physically After Recovery46:35 - How Meatstock Led to Another Infection and a Second Major Surgery54:30 - What Recovery After Amputation Really Looks Like58:57 - The USD 3.1 Million Hospital Bill, Prosthetic Rehab and Starting Over1:04:00 - Why Community, Carnivore and Faith Kept Her Going1:07:58 - Another Infection, Healing Setbacks and Her New Nutrition Goal1:12:44 - What Mary Ann Eats in a Day to Heal and Gain Strength1:15:00 - How People React to Her Prosthetic in Public1:19:57 - Her Message on Purpose, Perspective and Serving Others1:21:07 - Why Eating More Was the Key to Healing on Carnivore1:25:41 - What's Next for Mary Ann Peters and Where to Find Her

On this episode host Beth Friedman engages Bobby Reddy, Jr., PhD, Co-founder & CEO, Prenosis. Sepsis kills more people annually than all cancers combined - yet it receives a fraction of the research investment. Beth sits with Bobby Reddy Jr., leading Prenosis, a precision medicine company redefining how hospitals understand and treat their most critically ill patients. Reddy explains why decades of clinical trials for sepsis, acute heart failure, and pneumonia have failed and why the solution lies not in new drugs but in recognizing that these are not single diseases at all. Discover how Prenosis is using AI, deep biomarker data, and real-time EHR integration to characterize each patient's unique biology in under an hour, and what a landmark BARDA-funded trial could mean for the future of critical care.

Today we have another Pulm PEEPs Pearls episode about a core critical care topic. Furf and Monty will be giving a high level overview of the use of steroids in sepsis including a review of the relevant literature and recent guidelines, and pragmatic bedside points. Contributors This episode was prepared with research by Pulm PEEPs Associate Editor George Doumat. Dustin Latimer, another Pulm PEEPs Associate Editor, assisted with audio and video editing. Key Learning Points Why Steroids in Sepsis? Steroids do not treat the infection — antimicrobials are always first and remain the cornerstone. The goal is addressing critical illness–related corticosteroid insufficiency (CIRCI), where cortisol production cannot keep up with the overwhelming inflammatory demand of septic shock. Hydrocortisone helps in two main ways: Blunts the dysregulated inflammatory response — tempers the excessive vasodilation and febrile response that drive harm beyond the infection itself. Restores vascular sensitivity to catecholamines — sepsis downregulates adrenergic receptors; steroids turn that responsiveness back on. Clinical takeaway: The first thing you notice is vasopressor weaning (or a bend in the escalation curve) — not a rapid improvement in fever or white count. Caveat: These trials predate modern sepsis phenotyping. None distinguish hyperinflammatory vs. hypoinflammatory responders — they treat all comers. The Evidence: Four Landmark Trials Every IM resident and critical care fellow will eventually journal-club these four. The most consistent signal across all of them is faster shock reversal and reduced vasopressor use; the mortality question remains unsettled. Trial (Year)NRegimenKey FindingAnnane (2002)~300Hydrocortisone + fludrocortisoneMortality benefit in ACTH non-responders; criticized methodology and messy cortisol-response testing; not cleanly replicated.CORTICUS (2008)~500Hydrocortisone aloneFaster shock reversal but no mortality benefit, regardless of cortisol responsiveness. Raised (later allayed) superinfection concern. Cornerstone for abandoning routine cort-stim testing.ADRENAL (2018)~3,800Hydrocortisone aloneFaster vasopressor weaning; no 90-day mortality benefit.APROCCHSS (2018)~1,200Hydrocortisone + fludrocortisoneMortality benefit at 90 days. Bottom line: Faster shock reversal is consistent. Mortality benefit appears in 2 of 4 trials (both used fludrocortisone) but not the others. A 2026 meta-analysis showed benefit for hydrocortisone + fludrocortisone vs. placebo, but not for hydrocortisone + fludrocortisone vs. hydrocortisone alone — suggesting hydrocortisone drives the main effect. Who Gets Steroids, and When? 2021 Surviving Sepsis: Consider steroids for norepinephrine or epinephrine ≥ 0.25 mcg/kg/min for ≥ 4 hours despite adequate resuscitation — a reasonable bedside trigger. Early 2026 update: Moved away from a specific numeric trigger — consider steroids when a septic patient is not responding well to vasopressors or has escalating requirements. Make a clinical decision. (Quality of evidence: low to moderate.) Go faster than the threshold when: Known/suspected adrenal insufficiency or home steroids, or florid pressor-requiring shock on arrival. A practical escalation sequence: escalating norepinephrine → add vasopressin (per VASST) → then add steroids if requirements keep climbing. Do NOT wait for an ACTH stimulation test. It does not reliably predict who responds and only delays treatment. Sepsis is an elevated-cortisol state but can dissociate ACTH and cortisol, and cortisol-binding globulin is depleted — the test is too messy to guide care. What to Give: The Regimen Standard dose: Hydrocortisone 200 mg/day, typically 50 mg IV Q6H. (Original trials often used continuous infusions, rarely used in the U.S.) Some start with a 100 mg bolus to gain control. Higher dose: If chronically on steroids / adrenally insufficient, consider ~300 mg/day (e.g., 100 mg Q8H). Fludrocortisone: Unsettled. The two mortality-benefit trials added it (50 mcg PO/NG/OG daily), but hydrocortisone already has mineralocorticoid activity and meta-analyses don't show added benefit over hydrocortisone alone. Most clinicians omit it — adding it is reasonable and safe, just be honest about the uncertainty. Duration & Tapering Typical course: ~7 days is most common. Trial practices varied (ADRENAL ~7 days; VANISH used a taper after 6 days; some continue until pressors are off). No taper needed. You do not need to taper for adrenal insufficiency after a short course — just stop. If pressors dramatically rebound, you can restart, but most patients have gained the benefit they'll get by day 7. Pitfalls & Safety Hyperglycemia: Expected and must be managed (monitor closely; insulin drip if needed). No signal for major DKA / severe complications in the trials. Superinfection / fungal infection: The most-quoted concern, but the overall literature does not show a convincing, statistically significant increase. Be disciplined about stopping on schedule. Muscle weakness: Steroids can worsen critical illness myopathy; a short 7-day course likely has limited effect, but be aware. Other: GI bleeding (follow general PPI prophylaxis guidance) and sodium disturbances (watch for hyper-/hyponatremia). Two things we know: (1) steroids shorten duration of vasopressor support, and (2) they are relatively safe in sepsis. Whether they improve mortality — and in whom — remains open. The Five Pulm PEEPs Pearls Mechanism: Steroids restore catecholamine vascular sensitivity and blunt dysregulated inflammation. The clinical target is vasopressor weaning, not infection treatment. Evidence: Faster shock reversal is the most consistent finding. Mortality benefit is seen in 2 of 4 trials but not the others — still controversial. Some patients likely benefit; we don't yet know who. Trigger: A practical 2021 threshold is levo/epi ≥ 0.25 mcg/kg/min for ≥ 4 hours. Newer guidance drops the strict number — make a clinical decision based on poor pressor response or escalation. Dose: Hydrocortisone 200 mg/day (e.g., 50 mg Q6H). Adding fludrocortisone mirrors two trials, but meta-analyses find no benefit over hydrocortisone alone. Safety: Steroids appear safe in sepsis. Monitor and treat hyperglycemia; no marked increase in superinfection. References and Further Reading Annane, Djillali et al. “Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock.” JAMA vol. 288,7 (2002): 862-71. doi:10.1001/jama.288.7.862 Sprung, Charles L et al. “Hydrocortisone therapy for patients with septic shock.” The New England journal of medicine vol. 358,2 (2008): 111-24. doi:10.1056/NEJMoa071366 Venkatesh, Balasubramanian et al. “Adjunctive Glucocorticoid Therapy in Patients with Septic Shock.” The New England journal of medicine vol. 378,9 (2018): 797-808. doi:10.1056/NEJMoa1705835 Annane, Djillali et al. “Hydrocortisone plus Fludrocortisone for Adults with Septic Shock.” The New England journal of medicine vol. 378,9 (2018): 809-818. doi:10.1056/NEJMoa1705716 Sun, Alin et al. “Correction: Hydrocortisone combined with fludrocortisone for treatment of adults with septic shock: an updated meta-analysis and systematic review.” Frontiers in medicine vol. 13 1811616. 2 Mar. 2026, doi:10.3389/fmed.2026.1811616 Prescott, Hallie C et al. “Executive Summary: Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026.” Critical care medicine vol. 54,4 (2026): 715-724. doi:10.1097/CCM.0000000000007089

Podcast summary of articles from the April 2026 edition of the Journal of Emergency Medicine from the American Academy of Emergency Medicine.  Topics include bystander CPR, Sepsis, Regional Anesthesia under POCUS, Toxicology, Diabetes, and HIV screening.  Guest speaker is Dr. Kinda Sweidan.

**Tattoos, Traffic, and Sepsis: The Left's Great Blind Spot** In this multi-topic segment, the hosts expose deep-seated double standards on the national stage. The monologue starts with the disturbing surge of Maine progressive candidate Graham Platner, who secured 73% of the vote despite ex-girlfriend reports confirming he has an SS Totenkopf Nazi tattoo. The host compares Platner's political insulation to a 13-year-old in Richland County, South Carolina, who faced full hate-crime enhancements for graffitiing a swastika, pointing out the gross hypocrisy of the establishment. Shifting to the border crisis, the commentary highlights Department of Homeland Security Head Markwayne Mullin's report that the Trump administration has rescued 146,000 human-trafficked migrant children. The host blasts the previous administration for staffing a child crisis line with just a single person—leaving 65,000 distress calls unanswered—and praises Florida's local law-enforcement deputization model over South Carolina's inaction. Finally, the segment transitions to a rare positive note on AI technology, celebrating a new software system in Florida hospitals that successfully cut patient sepsis mortality rates in half. Graham Platner, Maine Senate primary, Hate crime laws, Richland County, Markwayne Mullin, Migrant children, Human trafficking, Border security, Local law enforcement, Pete Hegseth, Sepsis treatment, AI medical tech

Listener discretion is advised!!! References: Gabayan, G. Z., Gould, M. K., Weiss, R. E., Patel, N., Donkor, K. A., Chiu, V. Y., Yiu, S. C., Jones, J. P., Hoffman, J. R., & Sarkisian, C. A. (2016). Poor Outcomes After Emergency Department Discharge of the Elderly: A Case-Control Study. Annals of Emergency Medicine, 68(1), 43–51.e2. Ganetsky M, Lopez G, Coreanu T, Novack V, Horng S, Shapiro NI, Bauer KA. Risk of Intracranial Hemorrhage in Ground-level Fall With Antiplatelet or Anticoagulant Agents. Acad Emerg Med. 2017 Oct;24(10):1258-1266. Gokhroo, R. K., Ranwa, B. L., Kishor, K., et al. (2015). Sweating: A Specific Predictor of ST‐Segment Elevation Myocardial Infarction Among the Symptoms of Acute Coronary Syndrome: Sweating In Myocardial Infarction (SWIMI) Study Group. Clinical Cardiology, 39, 90–95. Knack SKS, Scott N, Driver BE, Prekker ME, Black LP, Hopson C, Maruggi E, Kaus O, Tordsen W, Puskarich MA. Early Physician Gestalt Versus Usual Screening Tools for the Prediction of Sepsis in Critically Ill Emergency Patients. Ann Emerg Med. 2024 Sep;84(3) Koo, A. (Oct 29, 2024). Putting Clinical Gestalt to Work in the Emergency Department. Available: https://www.acepnow.com/article/putting-clinical-gestalt-to-work-in-the-emergency-department/5/?singlepage=1 Long, B., Keim, S. M., Gottlieb, M., Carlson, J., Bedolla, J., & Reisdorff, E. J. (2024). Can I Discharge This Adult Patient with Abnormal Vital Signs From the Emergency Department? The Journal of Emergency Medicine, 67(4), e487–e493. Milner, K. A., Funk, M., Arnold, A., & Vaccarino, V. (2002). Typical symptoms are predictive of acute coronary syndromes in women. American Heart Journal, 143, 283–288.

EVEN MORE about this episode!The answers weren't as hidden as they seemed—the clues were there all along.In this episode, Julie Ryan uncovers surprising health insights, delivers moving spirit messages, and helps callers discover what their symptoms, loved ones, and pets have been trying to tell them.This episode also features unforgettable spirit communication, including messages from a beloved brother in spirit and heartfelt connections with cherished pets who have crossed over. You'll hear powerful validations, emotional healing, and extraordinary reminders that our connections with loved ones continue beyond physical life.Packed with health insights, intuitive guidance, pet communication, and spirit messages, this episode showcases the remarkable ways healing can happen when we look beyond the obvious and explore the deeper story behind our symptoms.Episode Chapters:(0:00:00) - Welcome and Brain Healing for Sundowning: Ping's Godmother Leilani from Vancouver(0:06:37) - Leaky Gut, Yeast Overgrowth, and Nystatin: Noelle from Charleston, South Carolina(0:13:21) - Osteoarthritis, the Gut Connection, and Keto: Fiona from Montreal (visiting St. Louis)(0:20:23) - Spirit Message from a Brother: Taleen from New York(0:23:00) - Back Surgery, Sepsis, and Vitamin C Protocol: Mindee from New Jersey(0:40:51) - Free Session Winner Announced(0:32:31) - Chronic Fatigue and Mold Sensitivity: Francesca from Chicago(0:38:00) - Missing Cat Milo: Lita from Melbourne, Australia(0:46:09) - Oreo the Cat's Final Message: Laura from Old Hickory, Tennessee(0:54:00) - Ley Lines, EMFs, and Psychiatric Health: Sandra from Perry Hall, Maryland➡️ Subscribe to Ask Julie Ryan YouTube➡️ Julie's Intuitive Trainings✏️ Ask Julie a Question!

A tale of 2 pneumonias—NASCAR racer Kyle Busch dead at 41 while Rudy Giuliani, age 81, survives critical care; Newly discovered evidence that Neanderthals were practicing dentistry—59,000 years ago! “Fatty 15”—does it measure up to the hype? Stem Wave—A shocking way to obtain pain relief; When to give antibiotics for a tick bite; Proposed ban on tobacco products for future generations of Brits aims to eradicate smoking.

We welcome back a Virtua Medical Group physician who also serves as the team doc for the Philadelphia Union, Dr. David Webner, to discuss the surprising passing of NASCAR racing legend, Kyle Busch. By report, Busch died from sepsis resulting from pneumonia. How common is this in otherwise healthy, young athletes? We discuss what may have happened and what may have been some contributing factors resulting in this catastrophic outcome.

Show notes at pharmacyjoe.com/episode1134 In this episode, I'll discuss an article about the pharmacokinetic and pharmacodynamic properties of IV push cefepime in critically ill patients with sepsis.

Why isn't there a cure for sepsis? Maybe it's because the government spends over a billion dollars on useless animal research. Kyle Busch's death is a reminder of how the U.S. is behind the times when it comes to curing a disease like sepsis.  PETA's Dr. Emily Trunnell talks to Emil Guillermo how PETA is suing NIH over wasteful sepsis experiments that have left us without a cure. The PETA Podcast PETA, the world's largest animal rights organization, is ten million strong and growing.  Hosted by Emil Guillermo.   Music provided by CarbonWorks. Please subscribe, rate, and review wherever you get your podcasts. Thanks for listening to THE PETA PODCAST!  © PETA, All rights reserved. copyright 2026

D&P Highlight: Pneumonia & sepsis. What to know, when to go. full 662 Tue, 26 May 2026 18:56:00 +0000 5QjA9YjdrI6X0mRyy9r5PrTCQHHvKHfb news The Dana & Parks Podcast news D&P Highlight: Pneumonia & sepsis. What to know, when to go. You wanted it... Now here it is! Listen to each hour of the Dana & Parks Show whenever and wherever you want! © 2025 Audacy, Inc. News https://player.amperwavepodcasting