Podcasts about Sepsis

In today's VETgirl online veterinary continuing education podcast, we're talking about the new veterinary sepsis definitions. Having clear definitions is crucial in making sure we're talking about the same type and severity of disease. Until now, our veterinary sepsis definitions have been largely adapted from human medicine. But let's be honest, our patients who have a talent for hiding illness don't always follow the same rules as humans. Having veterinary-specific definitions gives researchers a more consistent way to compare patients and studies, while giving clinicians a stronger foundation for recognizing sepsis, assessing illness severity, and shaping both today and tomorrow’s treatment recommendations.

LISTENER DISCRETION IS ADVISED! References: Alam N, Oskam E, et. al. PHANTASi Trial Investigators and the ORCA (Onderzoeks Consortium Acute Geneeskunde) Research Consortium the Netherlands. Prehospital antibiotics in the ambulance for sepsis: a multicentre, open label, randomised trial. Lancet Respir Med. 2018 Jan;6(1):40-50. Jouffroy, R., Annane, D., et. al. (2026). A 1-hour resuscitation bundle for prehospital management of septic shock. Critical Care Medicine. Knack, S. K. S., Scott, N., Driver, B. E., et al. (2024). Early physician gestalt versus usual screening tools for the prediction of sepsis in critically ill emergency patients. Annals of Emergency Medicine. Kotnarin R, Sirinawee P, Supasaovapak J. Impact of Prehospital Antibiotics on in-Hospital Mortality in Emergency Medical Service Patients with Sepsis. Open Access Emerg Med. 2023 May 26;15:199-206. Poynter, M. J., Farrugia, A., Kelly, E., & Simpson, P. M. (2023). Prehospital administration of antibiotics in addition to usual care versus usual care alone for patients with suspected sepsis – A systematic review. Paramedicine, 21, 52–65. Scales DC, et. al. Prehospital antibiotics and intravenous fluids for patients with sepsis: protocol for a 2×2 factorial randomised controlled trial. BMJ Open. 2025 May 27;15(5):e104257.

More insight into the Perez situation and a statement from his sister. Plus find out about Cindy Crawfod's daughter's fight with the devil. That's right. Stefanie sneaks in a new Howard Stern story!

Show notes at pharmacyjoe.com/episode1157 In this episode, I'll discuss differences in heart rate in patients with sepsis and AFib between phenylephrine and norepineprhine.

Hallie C. Prescott, MD, MSc, joins CHEST® Journal Podcast Moderator Alice Gallo De Moraes, MD, FCCP, to discuss her research into the impact of timely antibiotic delivery and fluid resuscitation on discharge to home after sepsis. DOI: 10.1016/j.chest.2026.03.002 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.  

In today's episode of Backpacker Radio presented by The Trek, brought to you by Topo Athletic, we are joined by Shawn Mahoney, aka the guy who carries a 20+ pound log named Larry over his shoulders, and with Larry he's hiked the Triple Crowner, Te Araroa, and just about all of the Northeast peaks. In this one, Shawn explains why the heck he carries a massive log everywhere he goes, describes losing Larry down a steep slope  on the PCT and spending two hours bushwhacking to retrieve him, recounts nearly dying from a septic heart infection and medically induced coma- and the impact that's had on his passion for backpacking, and details how he waking up at 4am, or earlier, to bank miles pre-sunrise. We also cover how he's raised several thousand dollars for charity, how you can contribute to his latest cause, his refusal to cook or cold-soak, and his party trick of solving a 9x9 rubik's cube while hiking, something he accomplishes mid interview. We wrap the show with Trek Propaganda of Kelly's favorite thru-hiking memories, a heroic dog intimidating a black bear to save a kid's life - maybe, a trail debate on losing your spoon vs. your shelter, the Triple Crown of movies everyone loves but you hate, and I review the uber-popular FarPointe Sun Hoodie but you'll probably have to wait til Thursday for that one so kinda nevermind. Topo Athletic: Use code "TREK15HIKE" at topoathletic.com. Gossamer Gear: Use code "BACKPACKERRADIO" for $20 off LT5 Trekking Poles at gossamergear.com.  Hyperlite Mountain Gear: Use code "BPRADIO15" for 15% of hyperlitemountaingear.com [divider] Interview with Shawn Mahoney and Larry the Log Shawn's Instagram Time stamps & Questions 00:05:40 - Reminders: Join us for a hiker meetup in Seattle, apply to vlog or blog for the Trek, listen to our episodes ad-free on Patreon! 00:10:30 - Introducing Shawn and Larry 00:12:30 - Why does Larry exist? 00:15:40 - How many times do you switch positions of the log over a day? 00:18:12 - Do you feel relief or separation anxiety when you put the log down? 00:20:11 - What branch of the military did you serve in, and how did you go from post-military training to hiking the AT with a log? 00:24:06 - Why a log instead of a weighted vest or rucksack? 00:27:07 - How do you get the log ready to be carried? What's the prep and sanding process? 00:29:32 - Have you thought about giving each log a unique name beyond "Larry"? 00:33:43 - What's it like navigating the AT bubble with a wide log — close calls with day hikers? 00:35:52 - What are all the charities you've raised money for, and how much in total? 00:40:45 - Discussion about the speed of hiking the AT 00:42:20 - Tell us about the septic heart infection and the 50/50 survival odds 00:47:30 - What was your mindset recovering from sepsis, and how did exercise become your outlet? 00:48:50 - What is your typical hiking style? 00:52:31 - Was there a moment where you had to reframe your identity from "not athletic" to what you are now? 00:54:14 - What do you do for work, and how do you afford to disappear for months at a time? 01:01:24 - You're headed to the Colorado Trail — what's the plan this time around? 01:03:10 - Have you ever done a thru-hike at a leisurely pace? 01:06:14 - What was Te Araroa like — especially navigating mud and terrain with a giant log? 01:10:15 - Are you ever in a gym, or is all your training done outside with the log? 01:11:01 - Do you have to be mindful about nutrition carrying 27 extra pounds all day? 01:15:34 - What is your base weight, and what's actually in the pack? 01:19:00 - What does Rubik's Cube problem-solving actually correlate to? 01:21:30 - Is there anything else you want to relay to listeners, and where can people find you? 01:22:05 - Peak Performance Question: What is your top performance enhancing or backpacking hack? Segments Trek Propaganda:  Turkenna Saw a Black Bear by The Norris Trio Before You Read Another Thru-Hiking Horror Story, Read This by Kelly Floro QOTD: Would you rather, on day 1 of your thru-hike, lose your shelter and have to always cowboy camp on the AT, or lose your spoon and have to eat all meals with only your hands? Triple Crown of movies everyone loves but you hate Mail Bag 5 Star Review [divider] Check out our sound guy @my_boy_pauly/ and his coffee. Sign up for the Trek's newsletter Leave us a voicemail! Subscribe to this podcast on iTunes (and please leave us a review)!  Find us on Spotify, Stitcher, and Google Play. Support us on Patreon to get bonus content. Advertise on Backpacker Radio Follow The Trek, Chaunce, Badger, and Trail Correspondents on Instagram. Follow Backpacker Radio, The Trek and Chaunce on YouTube. Follow Backpacker Radio on Tik Tok.  Our theme song is Walking Slow by Animal Years. A super big thank you to our Bob Peoples Award winner(s) from Patreon: Alex and Misty with NavigatorsCrafting, Alex Kindle, Austen McDaniel, Bill Jensen, Bret Mullins aka Cruizy, Bryan Alsop, Carl Lobstah Houde, Christopher Marshburn, Coach from Marion Outdoors, Eric Casper, Erik Hofmann, Ethan Harwell, Gillian Daniels, Greg Knight, Greg Martin, Griffin Haywood, Hailey Buckingham, Jackson Storm, JaredNotFromSubway, Jason Kiser, Jason "I Miss Chaunce" Snailer, Luke Netjes, Matty in AZ, Patrick Cianciolo, Randy Sutherland, Rebecca Brave, Rural Juror, Sawyer Products, The Saint Louis Shaman, Thirteen Adventures, Timothy Hahn, Tracy 'Trigger' Fawns A big thank you to our Cinnamon Connection Champions from Patreon: Bells, Benjy Lowry, Bonnie Ack, Brett Vandiver, Chris Pyle, David Neal, Dcnerdlet, Denise Krekeler, Jack Greene, Jeanie, Jeanne Latshaw, Lucas Hamilton, Merle Watkins, Peter, Quenten Jones, Ruth S, Salt Stain, Sloan Alberhasky, and Tyler Powers.

This month for the July 2026 episode of the RCEMLearning Podcast Becky and Chris talk through the second in a two parter on the Surviving Sepsis Campaign Guidelines update. Rob then speaks with Arya Rao about LLMs and clinical reasoning. If you'd like to email us, please feel free to do so here. After listening, complete a short quiz to have your time accredited for CPD at the RCEMLearning website! (02:13) Guidelines for EM - Surviving Sepsis Campaign Guideline (Part 2 of 2) Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 (22:50) Arya Rao - LLMs and Clinical Reasoning Large Language Model Performance and Clinical Reasoning Tasks (Rao et al., 2026)

Dr Janet Pope: QD Clinic: Can RA and Gout Manifest Simultaneously?  Dr. Mrinalini Dey QD312: Gout, Sepsis… or Both?  Daric Mueller, PA-C QD315: Pegloticase Immunomodulation: What's on the Menu?  Dr. Richard Conway: QD313: Don't Presume on IL-1 in Gout 

When experts are already there, they still may not see:"I think we need to go get our own data.""Sepsis smelled differently to him.""The more you dig into the individual, the more people you affect."One patient can teach what a system keeps missing...See BoldEncounters.TVA Table Turners SeriesAngela Finlay turns the tables again in Part 3.What If You Already Work in the Customer Space?Part 3 asks the harder question: what if you already work where the need happens, but still do not see it clearly? Mark brings in Dr. Todd Allen, whose sepsis work shows how doctors, nurses, phlebotomists, data, simulation, and direct observation helped move severe sepsis from a one-in-two mortality reality toward one-in-ten outcomes.Step Back and Look through New LensesBold Immersion is not only going somewhere new. Sometimes it means stepping back inside your own workplace with a fresh lens, watching one person at a time, and letting the senses find patterns that meetings, dashboards, and authority miss. Here, observation becomes more than a business tactic. It becomes a way to save lives, redesign care, serve customers, and build evidence no one can dismiss.Inside This Episode• Why ER doctors still needed a new lens inside the ER.• How a phlebotomist smelled signs in sepsis innovation.• Why studying one patient can help a system affect many.• How authoritative thinking delays care and needs to loosen.• What hospital rooms, produce pricing, and pediatric MRIs reveal about going to the scene.Go Deeper — Premium Action PlanThis Table Turners series culminates in a club-only Premium Action Plan led by Mark. Start now by choosing one familiar workflow you think you already understand. Watch it again as if new: who waits, who repeats work, who has hidden knowledge, what gets delayed, and what one person reveals about the whole system.Listen + Connecthttps://www.BoldEncounters.TVAngela Finlay, Table Turnerhttps://www.windwardhcm.comhttps://www.linkedin.com/in/ablumfinlay/Todd Allen, MDtodd.allen.ut@gmail.comlinkedin.com/in/todd-l-allen-md-facep-a8a7779Mark S. Cookhttps://www.WindfallPartners.comMoments To Revisit• Dr. Todd Allen explaining why a computer solution failed four times.• The phlebotomist whose senses caught what the system needed.• Mark connecting individual observation to larger population impact.• The hospital-ceiling video that made boredom impossible to ignore.• Dina Peters putting 400 hours a month back into produce service.Final ThoughtMark reveals that being near the work is not the same as seeing it. Real advantage comes when a professional steps back, gathers firsthand data, honors hidden expertise, and runs toward the space of the problem with enough humility to be changed by what is actually there.Join Us!Watch Part 3, then continue into the detailed examples and Premium Action Plan at https://www.BoldEncounters.TVThank YouDr. Terry Clemmer and Dr. Todd Allen, sepsis improvement and emergency-medicine observation.IDEO and Diego Rodriguez, hospital-room and pediatric MRI observation.Thomas Franklin, 9/11 photojournalism proximity.Dina Peters, produce pricing and service-hours example.Subaru of Indiana Automotive, zero-landfill preview.Calvin Cook—Caljo, original music, @Caljo MusicSacha Arias, Post Production, ska.films0211@gmail.comAliyah Peña, Post Production, aliyahmpena@gmail.comSkyler Maudsley, Video Editing, skylermaudsley@gmail.comRosalie McGinn, Social Media, rosalie.mcginn1@gmail.com

Sepsis management has traditionally focused on timely antibiotic treatment, hemodynamic support, and source control, but emerging evidence suggests that outcomes may be shaped long before patients reach the ICU. In this episode of the Society of Critical Care Medicine (SCCM) Podcast, host Diane C. McLaughlin, DNP, AGACNP-BC, CCRN, FCCM, speaks with Sayed Abdulmotaleb Almoosawy, MBChB (Hons), about his article “The Association Between Socioeconomic Position and Mortality in Patients With Sepsis and Septic Shock—A Systematic Review and Meta-Analysis,” published in the April 2026 issue of Critical Care Medicine. Drawing on 13 observational studies that encompassed nearly 4 million patients, the analysis evaluates how factors such as insurance status, income, education, and neighborhood deprivation relate to short-term mortality outcomes. The findings reveal a consistent association between lower socioeconomic position and increased mortality, with lack of private insurance demonstrating the strongest signal—likely reflecting barriers to timely access to care and delayed presentation. This episode challenges clinicians and researchers alike to recognize the link between socioeconomic disadvantages and worse sepsis outcomes, highlighting the need to collect equity-relevant data and reduce gaps in care to improve survival for critically ill patients. Resources referenced in this episode: Almoosawy SA, Fernando SM, Rochwerg B, et al. The association between socioeconomic position and mortality in patients with sepsis and septic shock—a systematic review and meta-analysis. Crit Care Med. 2026;54(4):692-700. Prescott HC, Antonelli M, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026. Crit Care Med. 2026;54(4):725-812.

This episode features Professor Bram Rochwerg discussing the latest guidelines on surviving sepsis, covering evidence-based practices, fluid management, vasopressor use, and emerging therapies. Gain insights into how expert panels synthesize evidence to guide critical care in sepsis management.Key Topics Covered: Sepsis guideline updates 2026Evidence synthesis and recommendation strengthFluid resuscitation strategies and targetsVasopressor use and peripheral administrationEmerging therapies: Methylene blue, steroids, bicarbonateBiomarkers and diagnostics in sepsisLinks: Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 | SCCMExecutive Summary: Surviving Sepsis Campaign:... : Critical Care Medicine

Show notes at pharmacyjoe.com/episode1149 In this episode, I'll discuss the impact of pharmacist involvement on hospital sepsis response teams.

Fred Turner is the Founder and CEO @ Curative, one of the wildest stories in tech. Fred scaled a COVID testing business from $0 to $5BN in revenue and took the team from 7 to 7,000 employees in just 9 months. They did over 206,000 COVID tests in a single day and signed contracts in the 100s of $Ms with several of the largest states. Today, Curative is a unicorn health insurance business taking on the incumbents for one of the largest markets in healthcare.  AGENDA: 00:00 How Did a Spare-Time COVID Test Become a $5BN Business? 07:00 How Do You Go From Testing Cows to STDs, Sepsis and COVID? 21:00 When Did Fred Realise COVID Was Massive—and How Did Curative Scale to $5BN? 36:00 Why Pivot Into Health Insurance—and What Is Broken About US Healthcare? 40:00 How Is AI Rebuilding Curative—and Which Departments Go to Zero? 45:00 Is SaaS Dead? Why Is Curative Cutting 80% of Its Software Spend? 48:00 Are Legacy Insurers Screwed? What Will Anthropic Be Worth in Three Years? 59:00 Will AI Make Companies Smaller? Which Jobs Will Survive? 1:10:00 Why Nuclear—and Could Subcritical Become Bigger Than Curative? 1:17:00 What Have Marriage and Fatherhood Taught Fred? What Has He Changed His Mind On?    

Es beginnt harmlos: Der 14-jährige Elia kehrt mit einem leichten Husten aus dem Skilager zurück. Doch sein Zustand verschlechtert sich zunehmend, sodass ihn seine Eltern in die Notaufnahme des Kantonsspitals Baden bringen. Trotz anhaltender Beschwerden wird Elia von den Ärztinnen nach Hause geschickt – zum Unverständnis seiner Eltern. Vier Tage später stirbt er an einem septischen Schock und Multiorganversagen. Gegen mehrere Ärzte des Kantonsspitals läuft inzwischen ein Strafverfahren. Es gilt die Unschuldsvermutung. Dass sich Eltern zu wenig ernst genommen fühlen, war auch in Luzern bereits Thema. Vor einem Jahr starb dort ein einjähriger Bub an einer bakteriellen Infektion, nachdem seine Mutter im Kinderspital vergeblich auf den kritischen Zustand hingewiesen haben soll. Deshalb hat das Kinderspital Luzern als erstes Schweizer Spital «Martha's Rule» eingeführt: Wenn Eltern mit der ärztlichen Einschätzung nicht einverstanden sind, können sie eine unabhängige Zweitmeinung einholen. Was ist im Fall Elia passiert? Was ist «Martha's Rule» genau – und inwiefern kann sie künftig Leben retten? Und bedeutet sie einen Kulturwandel in den Spitälern? Janina Gehrig, Redaktorin im Ressort Leben, hat den Fall von Elia recherchiert, Bundeshausredaktor Markus Brotschi die Hintergründe zu «Martha's Rule». In der neuen Folge des täglichen Podcasts «Apropos» ordnen sie den Fall ein und erklären, wie die Regel die Sicherheit von Patientinnen und Patienten verbessern könnte. Host: Alexandra Aregger Produzentin: Valeria Mazzeo Mehr zu Elias Fall und «Martha's Rule» Teil 1: Der Fall von Elias und wie er an einer nicht erkannten Sepsis starb Teil 2: Der Fall von Elias – wurde der Bericht beschönigt? Martha's Rule: Kinderspital Luzern führt Notknopf für Eltern ein Unser Tagi-Spezialangebot für Podcast-Hörer:innen: tagiabo.chHabt ihr Feedback, Ideen oder Kritik zu «Apropos»? Schreibt uns an podcasts@tamedia.ch Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Sepsis is fast, deadly, and often misdiagnosed — and when hospitals don't listen, parents pay the price.In this powerful episode, Risa shares her family's real-life nightmare after her son, Nicholas, was repeatedly misdiagnosed with a virus while suffering from sepsis. What started as a routine hospital visit turned into a fight for survival, exposing serious flaws in the healthcare system and the devastating consequences of medical negligence.This conversation is a must-listen for parents, caregivers, and anyone navigating the healthcare system. Risa's story is a reminder that parental instincts matter, advocacy saves lives, and accountability in hospitals is long overdue.In this episode, we discuss:How sepsis is commonly misdiagnosed in childrenWhy parents must trust their instincts — even when doctors dismiss concernsWhat really happens inside the ICU during a medical crisisThe emotional toll medical negligence takes on familiesWhy hospital accountability and patient advocacy matterHow awareness and education can prevent future tragediesThis is not just a story — it's a warning, a call to action, and a mission to protect other families.⏱️ Chapters00:00 – A Mother's Nightmare: Nicholas's Sepsis Story02:12 – Life Before the Crisis: A Normal Family03:39 – The Warning Signs Doctors Ignored07:22 – The ER Visit That Changed Everything08:52 – Inside the ICU: Fighting for Survival09:48 – Missed Opportunities and Medical Negligence15:00 – The Ripple Effect: Other Families' Stories16:47 – Systemic Failures in Healthcare19:02 – From Trauma to Advocacy21:35 – Nicholas's Long Road to Recovery27:54 – Life After Sepsis35:42 – Hospital Accountability & Legislative Change44:52 – Finding Strength, Purpose, and Hope

Julie Yoo sits down with Dr. Suchi Saria, founder and CEO of Bayesian Health, to discuss the current state of clinical AI and what it takes to deploy AI systems in real-world healthcare settings. While much of the recent attention around AI has focused on copilots, chatbots, and administrative workflows, Saria argues that the greatest opportunity lies in helping clinicians make better decisions at the point of care. She explains how Bayesian Health's clinical intelligence platform continuously analyzes multimodal patient data to identify signs of deterioration, sepsis, and other high-risk conditions before they become medical emergencies. The conversation explores FDA approval, reimbursement, clinician trust, AI governance, hospital workflows, and why healthcare requires a higher standard of evidence than most software categories. Along the way, Saria shares lessons from bringing AI into clinical practice, the future of proactive medicine, and why the next era of healthcare may be defined by continuous intelligence rather than reactive care.   Resources: Follow Suchi Saria on X: https://x.com/suchisaria Follow Julie Yoo on X: https://x.com/julieyoo   Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

About our Guests: Fran Balamuth, MD, PhD, MSCE, is division chief of Pediatric Emergency Medicine at the Children's Hospital of Philadelphia. Dr. Balamuth's research interests focus on pediatric sepsis recognition using epidemiologic and translational approaches, for which she has received NIH and foundation funding. She is the co-PI of the PROMPT BOLUS trial, a multinational pragmatic trial comparing saline vs balanced fluids in pediatric sepsis, which will be the largest acute care pediatric trial in history. In addition, she co-leads the CHOP Pediatric Sepsis Program, which supports and promotes local clinical, research, educational, and quality-improvement initiatives related to sepsis. She is an internationally recognized sepsis leader, and has been invited to serve on the national steering committee for the Improving Pediatric Sepsis Outcomes quality collaborative through the US Children's Hospital Association, and 2 international task forces focused on defining pediatric sepsis through the US Centers for Disease Control and Prevention and the Society of Critical Care Medicine.Scott L. Weiss, MD, MSCE, FCCM, is a Professor of Pediatrics & Pathology and Genomic Medicine at Thomas Jefferson University and division chief of Critical Care Medicine at Nemours Children's Hospital, Delaware. Previously, Dr. Weiss was on the faculty at the Children's Hospital of Philadelphia, where he earned recognition as an international expert in pediatric sepsis. Dr. Weiss' NIH-funded research focuses on epidemiology, fluid resuscitation, and mitochondrial dysfunction in pediatric sepsis. Dr. Weiss is an international expert in pediatric sepsis and served as the co-PI of the PRoMPT BOLUS trial.Nathan Kuppermann, MD, MPH, is Executive Vice President and Chief Academic Officer of Children's National Hospital and Director of the Children's National Research Institute. He also serves as chair of the Department of Pediatrics and associate dean of Pediatric Academic Affairs at the George Washington University School of Medicine and Health Sciences. He is an internationally recognized clinical trialist in pediatric trauma, pediatric DKA, and acute pediatric infections. As the original chair of the Pediatric Emergency Medicine Applied Research Network (PECARN); his research is focused on clinical trials and clinical prediction rules using large cohorts of acutely ill and injured children. Dr. Kuppermann served as the senior investigator of the PRoMPT BOLUS trial.Selected References:Weiss SL, Balamuth F, Long E, Thompson GC, Hayes KL, Katcoff H, Cook M, Tsemberis E, Hickey CP, Williams A, Williamson-Urquhart S, Borland ML, Dalziel SR, Gelbart B, Freedman SB, Babl FE, Huang J, Kuppermann N; Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis (PRoMPT BOLUS) Investigators of the PECARN, PERC, and PREDICT Networks. PRagMatic Pediatric Trial of Balanced vs nOrmaL Saline FlUid in Sepsis: study protocol for the PRoMPT BOLUS randomized interventional trial. Trials. 2021 Nov 6;22(1):776. doi: 10.1186/s13063-021-05717-4. Erratum in: Trials. 2025 Oct 7;26(1):390. doi: 10.1186/s13063-025-09164-3. PMID: 34742327; PMCID: PMC8572061.Weiss SL, Balamuth F, Thurm CW, Downes KJ, Fitzgerald JC, Laskin BL. Major Adverse Kidney Events in Pediatric Sepsis. Clin J Am Soc Nephrol. 2019 May 7;14(5):664-672. doi: 10.2215/CJN.12201018. Epub 2019 Apr 18. PMID: 31000518; PMCID: PMC6500940.Semler MW, Self WH, Wanderer JP, Ehrenfeld JM, Wang L, Byrne DW, Stollings JL, Kumar AB, Hughes CG, Hernandez A, Guillamondegui OD, May AK, Weavind L, Casey JD, Siew ED, Shaw AD, Bernard GR, Rice TW; SMART Investigators and the Pragmatic Critical Care Research Group. Balanced Crystalloids versus Saline in Critically Ill Adults. N Engl J Med. 2018 Mar 1;378(9):829-839. doi: 10.1056/NEJMoa1711584. Epub 2018 Feb 27. PMID: 29485925; PMCID: PMC5846085.Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & ZacSupport the showHow to support PedsCrit:Please complete our Listener Feedback SurveyPlease rate and review on Spotify and Apple Podcasts!Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com.  You can also check out our website at http://www.pedscrit.com. Thank you for listening to this episode of PedsCrit!

This month for the June 2026 episode of the RCEMLearning Podcast Becky and Chris talk through the first in a two parter on the Surviving Sepsis Campaign Guidelines update. Rob then speaks with Alison Tavare about the NCEPOD learning disability report. If you'd like to email us, please feel free to do so here. After listening, complete a short quiz to have your time accredited for CPD at the RCEMLearning website! (01:56) Guidelines for EM - Surviving Sepsis Campaign Guideline (Part 1 of 2) Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 (27:31) NCEPOD Acute Illness in people with a learning disability - Alison Tavare NCEPOD - Acute illness in people with a learning disability

Just as pneumonia isn't “just a cold,” the pneumococcal vaccine does much more than just protect yourself or your child against pneumonia. Listen in and learn from experts Robert H. Hopkins, Jr., MD, and Brenda L. Tesini, MD, how to discuss the full benefits of pneumococcal vaccine.  Topics covered include: Burden of pneumococcal disease among pediatric and older adult populations in the United States Risk factors for severe pneumococcal disease Which pneumococcal vaccines to use for certain populations and why How pneumococcal vaccination protects from long-term sequelae and potential community benefits of vaccination Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify. Presenters: Robert H. Hopkins, Jr., MD Professor of Internal Medicine and Pediatrics Division of General Internal Medicine University of Arkansas for Medical Sciences, School of Medicine Little Rock, Arkansas Brenda L. Tesini, MD Associate Professor of Medicine, Pediatrics, and Community Health Division of Infectious Diseases University of Rochester Medical Center Rochester, New York Link to program page: https://bit.ly/3SuymiN Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Book a free consultation call with Robert Sikes to break through your keto or low carb plateau here: https://www.ketobodybuilding.com/callA 30 year eating disorder drove her from 70 lbs to 220 lbs, through anorexia, sepsis, and back to healing with carnivore. In episode 894 of the Savage Perspective Podcast, host Robert Sikes sits down with Mary Ann Peters for a raw story of food noise, restriction, weight loss, weight gain, recovery, and faith. Mary Ann shares how childhood shame, years of disordered eating, and not eating enough on carnivore hurt her health, and how changing her nutrition helped her heal. This Savage Perspective Podcast episode covers eating disorder recovery, keto, carnivore, healing, mental health, body image, and learning to eat for strength, peace, and a better life.Follow Mary on IG: https://www.instagram.com/peglegcarnivore/Get Keto Brick: https://www.ketobrick.com/Subscribe to the podcast: https://open.spotify.com/show/42cjJssghqD01bdWBxRYEg?si=1XYKmPXmR4eKw2O9gGCEuQChapters0:00 - Mary Ann Peters' Backstory and How Her Eating Disorder Began6:16 - How a College Breakup Turned Food Into a Coping Mechanism12:23 - From Paleo to Carnivore: What Actually Helped Her Heal?20:16 - How a Hot Tub Infection Led to Sepsis, Organ Failure and Limb Loss30:49 - Learning to Walk Again and Why Her Parents Saw Carnivore as Dangerous37:47 - How Faith, Surrender and a Near-Death Experience Changed Her Perspective44:21 - Why Carnivore Helped Her Mentally and Physically After Recovery46:35 - How Meatstock Led to Another Infection and a Second Major Surgery54:30 - What Recovery After Amputation Really Looks Like58:57 - The USD 3.1 Million Hospital Bill, Prosthetic Rehab and Starting Over1:04:00 - Why Community, Carnivore and Faith Kept Her Going1:07:58 - Another Infection, Healing Setbacks and Her New Nutrition Goal1:12:44 - What Mary Ann Eats in a Day to Heal and Gain Strength1:15:00 - How People React to Her Prosthetic in Public1:19:57 - Her Message on Purpose, Perspective and Serving Others1:21:07 - Why Eating More Was the Key to Healing on Carnivore1:25:41 - What's Next for Mary Ann Peters and Where to Find Her

On this episode host Beth Friedman engages Bobby Reddy, Jr., PhD, Co-founder & CEO, Prenosis. Sepsis kills more people annually than all cancers combined - yet it receives a fraction of the research investment. Beth sits with Bobby Reddy Jr., leading Prenosis, a precision medicine company redefining how hospitals understand and treat their most critically ill patients. Reddy explains why decades of clinical trials for sepsis, acute heart failure, and pneumonia have failed and why the solution lies not in new drugs but in recognizing that these are not single diseases at all. Discover how Prenosis is using AI, deep biomarker data, and real-time EHR integration to characterize each patient's unique biology in under an hour, and what a landmark BARDA-funded trial could mean for the future of critical care.

Today we have another Pulm PEEPs Pearls episode about a core critical care topic. Furf and Monty will be giving a high level overview of the use of steroids in sepsis including a review of the relevant literature and recent guidelines, and pragmatic bedside points. Contributors This episode was prepared with research by Pulm PEEPs Associate Editor George Doumat. Dustin Latimer, another Pulm PEEPs Associate Editor, assisted with audio and video editing. Key Learning Points Why Steroids in Sepsis? Steroids do not treat the infection — antimicrobials are always first and remain the cornerstone. The goal is addressing critical illness–related corticosteroid insufficiency (CIRCI), where cortisol production cannot keep up with the overwhelming inflammatory demand of septic shock. Hydrocortisone helps in two main ways: Blunts the dysregulated inflammatory response — tempers the excessive vasodilation and febrile response that drive harm beyond the infection itself. Restores vascular sensitivity to catecholamines — sepsis downregulates adrenergic receptors; steroids turn that responsiveness back on. Clinical takeaway: The first thing you notice is vasopressor weaning (or a bend in the escalation curve) — not a rapid improvement in fever or white count. Caveat: These trials predate modern sepsis phenotyping. None distinguish hyperinflammatory vs. hypoinflammatory responders — they treat all comers. The Evidence: Four Landmark Trials Every IM resident and critical care fellow will eventually journal-club these four. The most consistent signal across all of them is faster shock reversal and reduced vasopressor use; the mortality question remains unsettled. Trial (Year)NRegimenKey FindingAnnane (2002)~300Hydrocortisone + fludrocortisoneMortality benefit in ACTH non-responders; criticized methodology and messy cortisol-response testing; not cleanly replicated.CORTICUS (2008)~500Hydrocortisone aloneFaster shock reversal but no mortality benefit, regardless of cortisol responsiveness. Raised (later allayed) superinfection concern. Cornerstone for abandoning routine cort-stim testing.ADRENAL (2018)~3,800Hydrocortisone aloneFaster vasopressor weaning; no 90-day mortality benefit.APROCCHSS (2018)~1,200Hydrocortisone + fludrocortisoneMortality benefit at 90 days. Bottom line: Faster shock reversal is consistent. Mortality benefit appears in 2 of 4 trials (both used fludrocortisone) but not the others. A 2026 meta-analysis showed benefit for hydrocortisone + fludrocortisone vs. placebo, but not for hydrocortisone + fludrocortisone vs. hydrocortisone alone — suggesting hydrocortisone drives the main effect. Who Gets Steroids, and When? 2021 Surviving Sepsis: Consider steroids for norepinephrine or epinephrine ≥ 0.25 mcg/kg/min for ≥ 4 hours despite adequate resuscitation — a reasonable bedside trigger. Early 2026 update: Moved away from a specific numeric trigger — consider steroids when a septic patient is not responding well to vasopressors or has escalating requirements. Make a clinical decision. (Quality of evidence: low to moderate.) Go faster than the threshold when: Known/suspected adrenal insufficiency or home steroids, or florid pressor-requiring shock on arrival. A practical escalation sequence: escalating norepinephrine → add vasopressin (per VASST) → then add steroids if requirements keep climbing. Do NOT wait for an ACTH stimulation test. It does not reliably predict who responds and only delays treatment. Sepsis is an elevated-cortisol state but can dissociate ACTH and cortisol, and cortisol-binding globulin is depleted — the test is too messy to guide care. What to Give: The Regimen Standard dose: Hydrocortisone 200 mg/day, typically 50 mg IV Q6H. (Original trials often used continuous infusions, rarely used in the U.S.) Some start with a 100 mg bolus to gain control. Higher dose: If chronically on steroids / adrenally insufficient, consider ~300 mg/day (e.g., 100 mg Q8H). Fludrocortisone: Unsettled. The two mortality-benefit trials added it (50 mcg PO/NG/OG daily), but hydrocortisone already has mineralocorticoid activity and meta-analyses don't show added benefit over hydrocortisone alone. Most clinicians omit it — adding it is reasonable and safe, just be honest about the uncertainty. Duration & Tapering Typical course: ~7 days is most common. Trial practices varied (ADRENAL ~7 days; VANISH used a taper after 6 days; some continue until pressors are off). No taper needed. You do not need to taper for adrenal insufficiency after a short course — just stop. If pressors dramatically rebound, you can restart, but most patients have gained the benefit they'll get by day 7. Pitfalls & Safety Hyperglycemia: Expected and must be managed (monitor closely; insulin drip if needed). No signal for major DKA / severe complications in the trials. Superinfection / fungal infection: The most-quoted concern, but the overall literature does not show a convincing, statistically significant increase. Be disciplined about stopping on schedule. Muscle weakness: Steroids can worsen critical illness myopathy; a short 7-day course likely has limited effect, but be aware. Other: GI bleeding (follow general PPI prophylaxis guidance) and sodium disturbances (watch for hyper-/hyponatremia). Two things we know: (1) steroids shorten duration of vasopressor support, and (2) they are relatively safe in sepsis. Whether they improve mortality — and in whom — remains open. The Five Pulm PEEPs Pearls Mechanism: Steroids restore catecholamine vascular sensitivity and blunt dysregulated inflammation. The clinical target is vasopressor weaning, not infection treatment. Evidence: Faster shock reversal is the most consistent finding. Mortality benefit is seen in 2 of 4 trials but not the others — still controversial. Some patients likely benefit; we don't yet know who. Trigger: A practical 2021 threshold is levo/epi ≥ 0.25 mcg/kg/min for ≥ 4 hours. Newer guidance drops the strict number — make a clinical decision based on poor pressor response or escalation. Dose: Hydrocortisone 200 mg/day (e.g., 50 mg Q6H). Adding fludrocortisone mirrors two trials, but meta-analyses find no benefit over hydrocortisone alone. Safety: Steroids appear safe in sepsis. Monitor and treat hyperglycemia; no marked increase in superinfection. References and Further Reading Annane, Djillali et al. “Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock.” JAMA vol. 288,7 (2002): 862-71. doi:10.1001/jama.288.7.862 Sprung, Charles L et al. “Hydrocortisone therapy for patients with septic shock.” The New England journal of medicine vol. 358,2 (2008): 111-24. doi:10.1056/NEJMoa071366 Venkatesh, Balasubramanian et al. “Adjunctive Glucocorticoid Therapy in Patients with Septic Shock.” The New England journal of medicine vol. 378,9 (2018): 797-808. doi:10.1056/NEJMoa1705835 Annane, Djillali et al. “Hydrocortisone plus Fludrocortisone for Adults with Septic Shock.” The New England journal of medicine vol. 378,9 (2018): 809-818. doi:10.1056/NEJMoa1705716 Sun, Alin et al. “Correction: Hydrocortisone combined with fludrocortisone for treatment of adults with septic shock: an updated meta-analysis and systematic review.” Frontiers in medicine vol. 13 1811616. 2 Mar. 2026, doi:10.3389/fmed.2026.1811616 Prescott, Hallie C et al. “Executive Summary: Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026.” Critical care medicine vol. 54,4 (2026): 715-724. doi:10.1097/CCM.0000000000007089

Podcast summary of articles from the April 2026 edition of the Journal of Emergency Medicine from the American Academy of Emergency Medicine.  Topics include bystander CPR, Sepsis, Regional Anesthesia under POCUS, Toxicology, Diabetes, and HIV screening.  Guest speaker is Dr. Kinda Sweidan.

Überlebt, aber nicht genesen: Diagnostik und Nachsorge beim Post-Sepsis-Syndrom

**Tattoos, Traffic, and Sepsis: The Left's Great Blind Spot** In this multi-topic segment, the hosts expose deep-seated double standards on the national stage. The monologue starts with the disturbing surge of Maine progressive candidate Graham Platner, who secured 73% of the vote despite ex-girlfriend reports confirming he has an SS Totenkopf Nazi tattoo. The host compares Platner's political insulation to a 13-year-old in Richland County, South Carolina, who faced full hate-crime enhancements for graffitiing a swastika, pointing out the gross hypocrisy of the establishment. Shifting to the border crisis, the commentary highlights Department of Homeland Security Head Markwayne Mullin's report that the Trump administration has rescued 146,000 human-trafficked migrant children. The host blasts the previous administration for staffing a child crisis line with just a single person—leaving 65,000 distress calls unanswered—and praises Florida's local law-enforcement deputization model over South Carolina's inaction. Finally, the segment transitions to a rare positive note on AI technology, celebrating a new software system in Florida hospitals that successfully cut patient sepsis mortality rates in half. Graham Platner, Maine Senate primary, Hate crime laws, Richland County, Markwayne Mullin, Migrant children, Human trafficking, Border security, Local law enforcement, Pete Hegseth, Sepsis treatment, AI medical tech

Listener discretion is advised!!! References: Gabayan, G. Z., Gould, M. K., Weiss, R. E., Patel, N., Donkor, K. A., Chiu, V. Y., Yiu, S. C., Jones, J. P., Hoffman, J. R., & Sarkisian, C. A. (2016). Poor Outcomes After Emergency Department Discharge of the Elderly: A Case-Control Study. Annals of Emergency Medicine, 68(1), 43–51.e2. Ganetsky M, Lopez G, Coreanu T, Novack V, Horng S, Shapiro NI, Bauer KA. Risk of Intracranial Hemorrhage in Ground-level Fall With Antiplatelet or Anticoagulant Agents. Acad Emerg Med. 2017 Oct;24(10):1258-1266. Gokhroo, R. K., Ranwa, B. L., Kishor, K., et al. (2015). Sweating: A Specific Predictor of ST‐Segment Elevation Myocardial Infarction Among the Symptoms of Acute Coronary Syndrome: Sweating In Myocardial Infarction (SWIMI) Study Group. Clinical Cardiology, 39, 90–95. Knack SKS, Scott N, Driver BE, Prekker ME, Black LP, Hopson C, Maruggi E, Kaus O, Tordsen W, Puskarich MA. Early Physician Gestalt Versus Usual Screening Tools for the Prediction of Sepsis in Critically Ill Emergency Patients. Ann Emerg Med. 2024 Sep;84(3) Koo, A. (Oct 29, 2024). Putting Clinical Gestalt to Work in the Emergency Department. Available: https://www.acepnow.com/article/putting-clinical-gestalt-to-work-in-the-emergency-department/5/?singlepage=1 Long, B., Keim, S. M., Gottlieb, M., Carlson, J., Bedolla, J., & Reisdorff, E. J. (2024). Can I Discharge This Adult Patient with Abnormal Vital Signs From the Emergency Department? The Journal of Emergency Medicine, 67(4), e487–e493. Milner, K. A., Funk, M., Arnold, A., & Vaccarino, V. (2002). Typical symptoms are predictive of acute coronary syndromes in women. American Heart Journal, 143, 283–288.

EVEN MORE about this episode!The answers weren't as hidden as they seemed—the clues were there all along.In this episode, Julie Ryan uncovers surprising health insights, delivers moving spirit messages, and helps callers discover what their symptoms, loved ones, and pets have been trying to tell them.This episode also features unforgettable spirit communication, including messages from a beloved brother in spirit and heartfelt connections with cherished pets who have crossed over. You'll hear powerful validations, emotional healing, and extraordinary reminders that our connections with loved ones continue beyond physical life.Packed with health insights, intuitive guidance, pet communication, and spirit messages, this episode showcases the remarkable ways healing can happen when we look beyond the obvious and explore the deeper story behind our symptoms.Episode Chapters:(0:00:00) - Welcome and Brain Healing for Sundowning: Ping's Godmother Leilani from Vancouver(0:06:37) - Leaky Gut, Yeast Overgrowth, and Nystatin: Noelle from Charleston, South Carolina(0:13:21) - Osteoarthritis, the Gut Connection, and Keto: Fiona from Montreal (visiting St. Louis)(0:20:23) - Spirit Message from a Brother: Taleen from New York(0:23:00) - Back Surgery, Sepsis, and Vitamin C Protocol: Mindee from New Jersey(0:40:51) - Free Session Winner Announced(0:32:31) - Chronic Fatigue and Mold Sensitivity: Francesca from Chicago(0:38:00) - Missing Cat Milo: Lita from Melbourne, Australia(0:46:09) - Oreo the Cat's Final Message: Laura from Old Hickory, Tennessee(0:54:00) - Ley Lines, EMFs, and Psychiatric Health: Sandra from Perry Hall, Maryland➡️ Subscribe to Ask Julie Ryan YouTube➡️ Julie's Intuitive Trainings✏️ Ask Julie a Question!

Pneumococcal vaccine recommendations are constantly evolving to respond to shifting patterns of infections, which is a good thing. However, the nuances can be complicated to explain to patients. Listen in to learn how experts Richard Colgan, MD and Brenda L. Tesini, MD, discuss changing pneumococcal vaccine recommendations. Topics covered include:  Epidemiologic changes: S. pneumoniae over time Burden on patients and the health system Adjustments to pneumococcal vaccine recommendations Considerations for vaccine selection Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify. Presenters: Richard Colgan, MD Professor Emeritus Department of Family and Community Medicine University of Maryland School of Medicine Medical Alumni Association Carolyn Frenkil Selvin Passen History of Medicine Scholar in Residence Baltimore, Maryland Brenda L. Tesini, MD Associate Professor of Medicine, Pediatrics, and Community Health Division of Infectious Diseases University of Rochester Medical Center Rochester, New York Link to program page: https://bit.ly/3RNHkHr Links mentioned in this episode: PneumoRecs VaxAdvisor App for Vaccine Providers | Pneumococcal | CDC Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

When you solve your own learning problems, you can accidentally build the resource everyone else was missing.In this episode, Matt sits down with Taim Dawod, a medical doctor from Norway who started a medical education YouTube channel in his first year of med school.Taim gets into his background studying anatomy and the problems he faced with the delivery of the learning. He goes on to explain the techniques he developed to solve those problems and how that led him to becoming a full-time content creator.He also talks about his view on the traditional lecture format in university teaching, and where it falls short for many students. He points out the gaps that are created through disjointed delivery and the importance of ‘the why' when communicating complex topics.Taim's main take is that everybody has something valuable to teach. There is someone out there that will benefit from what you have to say, and you will continue to sharpen your own knowledge along the way.Learning points from the episode include: 00:00 – 01:42 Intro01:42 – 05:42 Taim's medical background and journey to content creation05:42 – 08:14 Outsourcing vs. the journey of doing everything yourself08:14 – 11:13 The benefits of keeping consistent11:13 – 15:11 Communicating complex topics15:11 – 17:59 Visual mediums and the art of being concise17:59 – 19:10 The importance of ‘the why'19:10 – 21:34 Open education award and why learning should be free21:34 – 23:28 Helpful take away from Tromsø23:28 – 24:43 Taim's final piece of wisdom24:43 – 26:50 Where to connect with Taim and upcoming book release26:50 – 27:35 Taim's final take27:35 – 28:51 OutroImportant links and mentions: Subscribe to Taim Talks Med: https://www.youtube.com/@TaimTalksMedFollow Taim on Instagram: https://www.instagram.com/taimtalksmed/Taim's video on Sepsis and Septic Shock: https://www.youtube.com/watch?v=qVy_7shA3RM&t=117srb.gy/uoikzb

A tale of 2 pneumonias—NASCAR racer Kyle Busch dead at 41 while Rudy Giuliani, age 81, survives critical care; Newly discovered evidence that Neanderthals were practicing dentistry—59,000 years ago! “Fatty 15”—does it measure up to the hype? Stem Wave—A shocking way to obtain pain relief; When to give antibiotics for a tick bite; Proposed ban on tobacco products for future generations of Brits aims to eradicate smoking.

How untreated strep throat sent Ron into a coma the first time — in 2015What vasopressors are, why they saved his life, and why they cost What do you do when the love of your life is fighting for his life — and four kids are at home counting on you to hold everything together?Victoria Rosas is a former Dallas attorney, mom of four in a beautifully blended family, and one of the most quietly extraordinary women we've ever sat across from at the Moms Club.In 2022, her husband Ron — a former professional tennis player who competed for Notre Dame, played the pro tour, and coached their kids on the court — woke up feeling off. Within 24 hours, he was intubated. Within days, the medication saving his life was slowly taking something else: blood flow to all four of his limbs.Victoria was told multiple times he wasn't going to survive.He did. But what came next — nine surgeries, 70 hours in the operating room, nine weeks in Ohio, and coming home to a kindergartner and three kids on the verge of launching — is a story about what strength actually looks like when it has no other choice.

Sepsis is a global health emergency, with nearly half of all septic patients being children. In this episode of the Society of Critical Care Medicine (SCCM) Podcast, Samantha Gambles Farr, MSN, NP-C, CCRN, RNFA, speaks with Niranjan Kissoon, MD, MBBS, FRCP(C), FACPE, MCCM, about his Thought Leader presentation at the 2026 Critical Care Congress, Making Sepsis the Next Success Story in Global Health. The panel also discusses how access and equity play a part in how sepsis is treated. From a global perspective, Dr. Kissoon emphasizes that the most important thing is advocacy and prevention from a governmental level by creating national action plans, making sure the healthcare system is resilient, and utilizing technology and innovation to create better ways of providing care; and from a societal level by educating patients and families about nutrition, hygiene, vaccinations, and seeking care early. Niranjan Kissoon, MD, MBBS, FRCP(C), FACPE, MCCM, is a professor in the Department of Pediatrics (Pediatrics and Surgery, Emergency Medicine) at the University of British Columbia in Vancouver, British Columbia, Canada. He is the past president of the World Federation of Pediatric Critical and Intensive Care Societies and currently serves as president of the Global Sepsis Alliance. He is cochair of the pediatric Surviving Sepsis Campaign, vice president of the Canadian Sepsis Foundation, and chair of World Sepsis Day and the International Pediatric Sepsis Initiative. He also serves on the Sepsis Alliance USA and the African Sepsis Alliance advisory boards and is also a founding member of the Caribbean Sepsis Alliance.

We welcome back a Virtua Medical Group physician who also serves as the team doc for the Philadelphia Union, Dr. David Webner, to discuss the surprising passing of NASCAR racing legend, Kyle Busch. By report, Busch died from sepsis resulting from pneumonia. How common is this in otherwise healthy, young athletes? We discuss what may have happened and what may have been some contributing factors resulting in this catastrophic outcome.

Show notes at pharmacyjoe.com/episode1134 In this episode, I'll discuss an article about the pharmacokinetic and pharmacodynamic properties of IV push cefepime in critically ill patients with sepsis.

Hour 1 Segment 1 Tony starts the first hour of the show talking about the U.S. launching defensive strikes against Iran and intercepting multiple threatening drones. Tony also talks about President Donald Trump saying he doesn’t care about midterms and that Iran can’t outwait him. Hour 1 Segment 2 Tony talks about Markwayne Mullin drawing up plans to halt international flight processing in sanctuary cities. Tony also talks about the Ebola outbreak. Hour 1 Segment 3 Tony talks about the U.S. and Iran negotiators agreeing on a 60-day memo of understanding to extend ceasefire and launch negotiations on Iran’s nuclear program. Tony also talks about Alexandria Ocasio-Cortez mocked for wearing a hijab to an Eid event. Hour 1 Segment 4 Tony wraps up the first hour of the show talking about Hakeem Jeffries mocked for using an AI face tuned picture of himself wearing a New York Knicks hat. Hour 2 Segment 1 Tony starts the second hour of the show talking about Jill Biden saying she thought former President Joe Biden was having a stroke during his 2024 presidential debate. Hour 2 Segment 2 Tony talks about Costco grape plants sparking fears of devastating threats to American farms. Hour 2 Segment 3 Tony talks more about U.S. and Iran negotiators agreeing on a 60-day memo of understanding to extend ceasefire and launch negotiations on Iran’s nuclear program. Tony later gets into three more things: a $250 bill with President Donald Trump’s face on it, Maryland sheriffs suing over new state laws barring most cooperation with federal immigration agents, and a Democrat civil war over Graham Platner. Hour 2 Segment 4 Tony wraps up the second hour of the show talking about 4X Stanley Cup Champion Claude Lemieux passing away at the age of 60, a week after 2X NASCAR Cup Series Champion Kyle Busch passing away at the age of 41 from Sepsis. Hour 3 Segment 1 Tony starts the final hour of the show joined with Dr. Matt Will, economist from the University of Indianapolis, to talk about the latest inflation and fraud numbers. Hour 3 Segment 2 Tony talks more about the latest Ebola outbreak. Hour 3 Segment 3 Tony talks about Vice President J.D. Vance’s fraud taskforce. Hour 3 Segment 4 Tony wraps up another edition of the show talking more about the U.S. launching defensive strikes against Iran and intercepting multiple threatening drones. See omnystudio.com/listener for privacy information.

Hour 2 Segment 1 Tony starts the second hour of the show talking about Jill Biden saying she thought former President Joe Biden was having a stroke during his 2024 presidential debate. Hour 2 Segment 2 Tony talks about Costco grape plants sparking fears of devastating threats to American farms. Hour 2 Segment 3 Tony talks more about U.S. and Iran negotiators agreeing on a 60-day memo of understanding to extend ceasefire and launch negotiations on Iran’s nuclear program. Tony later gets into three more things: a $250 bill with President Donald Trump’s face on it, Maryland sheriffs suing over new state laws barring most cooperation with federal immigration agents, and a Democrat civil war over Graham Platner. Hour 2 Segment 4 Tony wraps up the second hour of the show talking about 4X Stanley Cup Champion Claude Lemieux passing away at the age of 60, a week after 2X NASCAR Cup Series Champion Kyle Busch passing away at the age of 41 from Sepsis. See omnystudio.com/listener for privacy information.

Gene opens the show with an assortment of sports stories including NBA Finals & Stanley Cup playoffs. Gene speaks on Nascar & Kyle Busch. Plus what does George Kittle want?

Full Hour 1 in The Sports Bar. Gene covers a variety of sports stories. Which MLB team is the modern day version of the moneyball team? Timmys shares his hot take.

Why isn't there a cure for sepsis? Maybe it's because the government spends over a billion dollars on useless animal research. Kyle Busch's death is a reminder of how the U.S. is behind the times when it comes to curing a disease like sepsis.  PETA's Dr. Emily Trunnell talks to Emil Guillermo how PETA is suing NIH over wasteful sepsis experiments that have left us without a cure. The PETA Podcast PETA, the world's largest animal rights organization, is ten million strong and growing.  Hosted by Emil Guillermo.   Music provided by CarbonWorks. Please subscribe, rate, and review wherever you get your podcasts. Thanks for listening to THE PETA PODCAST!  © PETA, All rights reserved. copyright 2026

D&P Highlight: Pneumonia & sepsis. What to know, when to go. full 662 Tue, 26 May 2026 18:56:00 +0000 5QjA9YjdrI6X0mRyy9r5PrTCQHHvKHfb news The Dana & Parks Podcast news D&P Highlight: Pneumonia & sepsis. What to know, when to go. You wanted it... Now here it is! Listen to each hour of the Dana & Parks Show whenever and wherever you want! © 2025 Audacy, Inc. News https://player.amperwavepodcasting

MONDAY HR 3 Monster Sports - Orlando Storm victory. Orlando City SC loss before the World Cup break. Nascar, F1 and Indy races. Kyle Busch impact. Pneumonia and Sepsis. NO WAKE ZONE fools!! See omnystudio.com/listener for privacy information.

In this World Shared Practice Forum Podcast, Drs. Mark Peters and Scott Weiss provide their expert insight on the methodology and development of the 2026 International Surviving Sepsis Campaign guidelines. They discuss challenges encountered during the process and review notable changes to these guidelines compared to previous iterations. The authors share the recommendations that will most impact their personal practice for patients with sepsis, and reflect on how we can improve global research infrastructure to address salient knowledge gaps in pediatric critical care. LEARNING OBJECTIVES - Understand the design and methodology for the 2026 Surviving Sepsis Campaign guidelines - Review notable changes in the 2026 sepsis guidelines compared to the 2020 edition - Discuss the implications of the altered recommendations for clinical practice changes - Consider methods to improve global pediatric research infrastructure and data organization AUTHORS Mark Peters, MBChB, PhD, MRCP, FFICM, FRCPCH Professor of Paediatric Intensive Care NIHR Senior Investigator UCL Great Ormond St Institute of Child Health Hon. Consultant Paediatric Intensivist Paediatric Intensive Care Unit and Children's Acute Transport Service Great Ormond St Hospital Scott Weiss, MD, MSCE Professor of Pediatrics and Pathology & Genomic Medicine, Division Chief of Critical Care, Vice-Chair of Research for the Department of Pediatrics, Nemours Children's Hospital, Sidney Kimmel Medical College at Thomas Jefferson University Jeffrey Burns, MD, MPH Emeritus Chief Division of Critical Care Medicine Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital Professor of Anesthesia Harvard Medical School DATE Initial publication date: May 26, 2026. ARTICLES REFERENCED & ADDITIONAL REFERENCES - Weiss SL, Peters MJ, Oczkowski SJW, et al. Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026. Pediatr Crit Care Med. 2026;27(4):379-434. https://pubmed.ncbi.nlm.nih.gov/41869844/ - Balamuth F, Weiss SL, Long E, et al. Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock. N Engl J Med. Published online April 24, 2026. https://pubmed.ncbi.nlm.nih.gov/42028918/ - Weiss SL, Balamuth F, Long E, et al. PRagMatic Pediatric Trial of Balanced vs nOrmaL Saline FlUid in Sepsis: study protocol for the PRoMPT BOLUS randomized interventional trial. Trials. 2021;22(1):776. Published 2021 Nov 6. https://pubmed.ncbi.nlm.nih.gov/34742327/ - Steven Pinker "Enlightenment Now” - https://stevenpinker.com/publications/enlightenment-now-case-reason-science-humanism-and-progress - Blood Poison: The Untold Story of Sepsis - https://amplifypublishinggroup.com/product/nonfiction/health-medicine-and-wellness/general-health-medicine-and-wellness/blood-poison/ TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/at/r9q8w9vhsbpg7wwzn35kbmz/202605_WSP_Peters_and_Weiss_Transcript.pdf Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge among healthcare providers worldwide who care for critically ill children across all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access, thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Peters MJ, Weiss SL, O'Hara J, Burns JP. Pediatric Surviving Sepsis: Insights From the Leadership. 05/2026. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/pediatric-surviving-sepsis-insights-from-the-leadership-by-m-peters-s-weiss-openpediatrics.

In this no-fluff, high-stakes episode of the PFC Podcast, Dennis sits down with Patrick Liebel - trauma/ICU surgeon to tackle the injury that makes every medic's stomach drop: penetrating abdominal trauma.When the golden hour stretches into days, evacuation is delayed, and your patient's belly is a black box of bleeding, contamination, and impending sepsis, what do you actually do? Patrick delivers hard-earned, practical wisdom on hemorrhage control, evisceration management, permissive hypotension, antibiotics, nutrition, peritonitis, and abdominal compartment syndrome — all tailored for the austere, resource-limited prolonged field care environment.If you carry a medic bag and might one day face a guy with his guts hanging out and no surgeon in sight, this episode is required listening. Real talk, real decisions, real consequences.Key Takeaways (Actionable Gold for Every Medic):Mesenteric torsion = widespread ischemia → never spin the bowel for hemorrhage control. Clamp or ligate targeted vessels instead.Clamping is fine in the heat of the moment — revise to ligation later when safe. Remember: every vessel has two ends.Eviscerated bowel is happier inside the abdomen. Tuck it back if you can (keep it wet, protect it). Only widen the defect if ischemia is imminent and you're in a controlled setting.Solid organ (liver/spleen) bleeding → permissive hypotension is your only friend. Titrate to mental status + palpable radial pulse. Track trends, not single numbers.Assume hollow viscus injury until proven otherwise. Hit it hard and early with antibiotics (Ceftriaxone + Flagyl is the practical winner most teams actually carry).Nutrition: If they're hungry, stable, soft abdomen, and no peritonitis after 1–2 days → feed them. Start slow, listen to the patient.Peritonitis = bad news. You've done everything possible with antibiotics and resuscitation — now you're buying time for definitive surgery.Abdominal compartment syndrome is rare with whole blood resuscitation but lethal if it develops. Watch for progressive distension + organ dysfunction (urine output drop + respiratory failure).Document everything. Trends in vitals, urine output, mental status, and abdominal exam are your lifeline in PFC.Chapters:00:00 – 01:30 Welcome & Patrick Liebel Introduction01:30 – 08:00 Hemorrhage Control: Clamping, Ligating, and Why You Should Never Spin the Bowel08:00 – 14:30 Evisceration Management — Tuck It, Widen It, or Leave It?14:30 – 25:00 Solid Organ Injuries & Permissive Hypotension in PFC25:00 – 35:00 Prolonged Critical Care Monitoring, Urine Output, and Trend Analysis35:00 – 42:00 Contamination Control, Antibiotics, and Hollow Viscus Injuries42:00 – 49:00 Nutrition, Ileus, and When to Feed49:00 – 57:00 Peritonitis, Sepsis, and Abdominal Compartment Syndrome57:00 – End Final Pearls, Nursing Care, and Closing ThoughtsFor more content, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.prolongedfieldcare.org⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Consider supporting us: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠patreon.com/ProlongedFieldCareCollective⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.lobocoffeeco.com/product-page/prolonged-field-care⁠

New strategies for tackling African Swine Fever. We ask how much is being done to stop it getting here in the first place.Yesterday the King delivered his speech outlining what the Government hopes to achieve in its next parliamentary session, no matter who is at the helm. How much was in there for farmers?A campaign has been launched to raise awareness of sepsis among farmers. Presented by Anna Hill and produced by Beatrice Fenton.

This episode covers sepsis in children.Notes: https://zerotofinals.com/paediatrics/infectiousdisease/paediatricsepsis/Questions: https://members.zerotofinals.com/Books: https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.

Welcome back to White Wine Question TimeOur guest today is the brilliant actor Jason Watkins, and this is a great conversation that starts with his incredible ancestry, and takes in his time studying at RADA, what he's learned about relationships and his reflections on the loss of his daughter to Sepsis. We promised Jason that in the notes for this episode we'd post links to the UK Sepsis Trust and the NHS so please take two minutes to familiarise yourselves with the symptoms - it isn't an exaggeration to say that reading these might help to save a life. SPOT THE SIGNS OF SEPSISNHS ADVICE ON SEPSISThanks to Jason for joining us, I hope you enjoy the chat,Cheers Hosted on Acast. See acast.com/privacy for more information.

Listener discretion is advised. Language. Adult themes. References: Anand Swaminathan, "Clinical Conundrum: Should We Always Treat Fever in Patients with Sepsis?", REBEL EM blog, December 17, 2024. Available at: https://rebelem.com/clinical-conundrum-should-we-always-treat-fever-in-patients-with-sepsis/. Jibril F, Sharaby S, Mohamed A, Wilby KJ. Intravenous versus Oral Acetaminophen for Pain: Systematic Review of Current Evidence to Support Clinical Decision-Making. Can J Hosp Pharm. 2015 May-Jun;68(3) Scott Weingart, MD FCCM. EMCrit 132 – MoTR – Toughness Part I with Michael Lauria. EMCrit Blog. Published on September 6, 2014. Accessed on May 8th 2026. Available at [https://emcrit.org/emcrit/toughness-michael-lauria-i/ ].

Listener discretion is advised.

Send us Fan MailDr. Lyubina Yankova, hospitalist at Yale, presents findings from a large retrospective multi-center analysis across 106 sites examining whether the combination of procalcitonin and C-reactive protein (CRP) can match or outperform the inflammatory marker combinations currently recommended by the 2021 AAP guidelines for risk-stratifying febrile infants between 8 and 60 days of age. She shares why this combination showed similar sensitivity but higher specificity for detecting invasive bacterial infections — meaning fewer false positives, fewer unnecessary lumbar punctures, and fewer unnecessary antibiotics. She also addresses the limitations of retrospective data, why preterm infants were excluded from this analysis and what future research in that population might look like, and what it would take for guideline committees to feel confident enough to incorporate this combination into routine practice.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Send us Fan MailPoint-of-care biomarkers for predicting sepsis mortality, not from a resource-rich academic center, but from a tertiary referral hospital in Tanzania. In this booth interview from PAS 2026, Ben and Daphna sit down with Dr. Abigail Sorensen, a pediatrician now based in East Africa, to discuss how a lasso model combining malnutrition, altered mental status, respiratory distress, and procalcitonin can risk-stratify children with sepsis at the bedside. The lessons here are not just for low-resource settings. They are for anyone trying to identify the sickest kids before it is too late, with the tools already in front of them.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!