JAMA Author Interviews: Covering research in medicine, science, & clinical practice. For physicians, researchers, & clinician

Susanna Naggie, MD, vice dean for research at Duke University's School of Medicine, discusses the ACTIV-6 trial of fluvoxamine for outpatient treatment of COVID-19 and outlines the role of platform trials during the pandemic. Hosted by JAMA Deputy Editor and Editorial Director for Equity Preeti Malani, MD, MSJ. Related Content: Effect of Fluvoxamine vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19

In the wake of new legal challenges to race-conscious admission policies, JAMA Interim Executive Editor Gregory Curfman, MD, discusses racial and ethnic diversity in undergraduate and medical school admission policies with Roy H. Hamilton, MD, MS, from the Perelman School of Medicine, University of Pennsylvania. Related Content: Defending Racial and Ethnic Diversity in Undergraduate and Medical School Admission Policies

JAMA Deputy Editor Preeti Malani, MD, MSJ, discusses potential next-generation COVID-19 vaccines with Peter Marks, MD, PhD, director of the Center for Biologics Evaluation and Research at the US Food and Drug Administration. Related Content: Urgent Need for Next-Generation COVID-19 Vaccines

In this JAMA author interview, we speak with Robert M. Califf, MD, Commissioner of the FDA, about a remarkable advance in the technology of hearing aids. Dr Califf has done important work to secure the entry of over-the-counter hearing aids into the market, providing a less expensive alternative to traditional hearing aids. In this interview, Dr Califf tells the story of how this technology has finally been made available to the public. Related Content: Over-the-counter Hearing Aids: From Research to Policy to Practice

Interview with Chris Zielinski, Visiting Research Fellow and Faculty of Health and Wellbeing at the University of Winchester, UK, James Kigera, Editor-in-Chief, Annals of African Surgery, and James Tumwine, Editor-in-Chief, African Health Sciences, authors of COP27 Climate Change Conference—Urgent Action Needed for Africa and the World. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD. Related Content: COP27 Climate Change Conference—Urgent Action Needed for Africa and the World Conflict and Climate Collide to Create an Acute Hunger Crisis for an Unprecedented 345 Million People Climate Justice and Health Children, Climate Justice, and Lessons From Puerto Rico

Interview with Gbenga Ogedegbe, MD, MPH, USPSTF member and coauthor of Screening for Obstructive Sleep Apnea in Adults: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Screening for Obstructive Sleep Apnea in Adults Screening for Obstructive Sleep Apnea in Adults Screening for Obstructive Sleep Apnea in Adults Screening for Obstructive Sleep Apnea USPSTF Updates Recommendation for Obstructive Sleep Apnea Screening in Adults

Interview with Carol Mangione, MD, MSPH, USPSTF chair and coauthor of Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons Menopausal Hormone Therapy for Prevention of Chronic Conditions

Interview with Martha Kubik, PhD, RN, USPSTF member and coauthor of Screening for Anxiety in Children and Adolescents: US Preventive Services Task Force Recommendation Statement, and Screening for Depression and Suicide Risk in Children and Adolescents: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Screening for Anxiety in Children and Adolescents Screening for Anxiety in Children and Adolescents Screening for Depression and Suicide Risk in Children and Adolescents Screening for Depression and Suicide Risk in Children and Adolescents Screening for Anxiety in Children and Adolescents Screening for Pediatric Anxiety Disorders

In this JAMA Author Interview, JAMA Interim Executive Editor Greg Curfman, MD, speaks with Mary M. McDermott, MD, professor of medicine at Northwestern University Feinberg School of Medicine, on current therapies for peripheral artery disease and a new clinical trial she directed on the use of telmisartan, an angiotensin receptor blocker, for patients with peripheral artery disease. Related Content: Effect of Telmisartan on Walking Performance in Patients With Lower Extremity Peripheral Artery Disease

JAMA Network Open Editor Frederick Rivara, MD, MPH, discusses approaches to reducing firearm violence with several JAMA Viewpoint authors: Sandro Galea, MD, DrPH (Boston University), Elinore J. Kaufman, MD, MSHP (University of Pennsylvania), and Roger A. Mitchell Jr, MD (Howard University). Topics include the state-level response to firearm-related harms, the paucity of data on firearm violence, and the pervasive health effects of firearm violence on neighborhoods and in the carceral system. Related Content: The Epidemiology of Firearm Injuries in the US: The Need for Comprehensive, Real-time, Actionable Data Violence and the Carceral State: A Public Health Continuum State Firearm Laws and Firearm-Related Mortality and Morbidity Examining the Impact of Firearm Safety Laws on Suicides Physicians and EMS Who Responded to Mass Shootings Develop Consensus Recommendations for Improving Care Approaches to Reducing Firearm Violence

Interview with Katrina E. Donahue, MD, MPH, USPSTF member and coauthor of Screening for Syphilis Infection in Nonpregnant Adolescents and Adults: US Preventive Services Task Force Reaffirmation Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: The Critical Need to Modernize Syphilis Screening Screening for Syphilis Infection in Nonpregnant Adolescents and Adults Screening for Syphilis Infection in Nonpregnant Adults and Adolescents Screening for Syphilis

Arguably, a clinician's most important role is providing an accurate and actionable diagnosis for patients. But challenges stand in the way, including tool limitations, inequitable access, and discontinuity of care. In this roundtable Q&A discussion, Urmimala Sarkar, MD, MPH (Zuckerberg San Francisco General Hospital and Trauma Center, UCSF), Jonathan H. Chen, MD, PhD (Stanford Center for Biomedical Informatics Research, Stanford University), and Harvey V. Fineberg, MD, PhD (Gordon and Betty Moore Foundation), discuss issues affecting diagnostic excellence, the emergence of artificial intelligence–driven tools, and ways to make the diagnostic process patient-focused. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, MD, PhD. Related Content: Decoding Artificial Intelligence to Achieve Diagnostic Excellence Diagnostic Excellence Achieving Diagnostic Equity in Cardiovascular Disease Achieving Diagnostic Excellence in the 21st Century Achieving Diagnostic Excellence

CRISPR genome editing is a revolutionary technology that can be used to make highly targeted changes in DNA in living cells. JAMA Associate Editor W. Gregory Feero, MD, PhD, Maine Dartmouth Family Medicine Residency, and Matthew J. Kan, MD, PhD, University of California San Francisco, discuss how CRISPR works and how CRISPR-based technologies are being used in ongoing trials to treat a wide variety of medical conditions. Related Content: Treatment of Genetic Diseases With CRISPR Genome Editing With First CRISPR Trials, Gene Editing Moves Toward the Clinic

Interview with Michael D. Cabana, MD, MA, MPH, USPSTF member and coauthor of Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents Screening for Type 2 Diabetes in Children and Adolescents

Over a nearly 40-year career at the head of the National Institute of Allergy and Infectious Diseases, Anthony Fauci, MD, has seen a seismic shift in the way that science is communicated to and received by the public. In conversation with JAMA Network Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, Fauci reflects on his career at NIAID, the joys and challenges of advising 7 presidents, and shares his strategies for communicating scientific information in an ever-changing environment. Related Content: Dr Fauci and the Art of Science Communication Dr Anthony Fauci—Communicating Science in a Polarized Era

Interview with John B. Wong, MD, USPSTF member and coauthor of Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults Statin Use for the Primary Prevention of Cardiovascular Disease in Adults Statins for the Prevention of Cardiovascular Disease Statin Usage in Primary Prevention—Comparing the USPSTF Recommendations With the AHA/ACC/Multisociety Guidelines Statins for Primary Cardiovascular Disease Prevention Statins and Primary Atherosclerotic Cardiovascular Disease Prevention—What We Know, Where We Need to Go, and Why Are We Not There Already?

President Biden has signed into law the Inflation Reduction Act containing important provisions related to prescription drug costs. JAMA Health Forum Editor John Z. Ayanian, MD, MPP, and Deputy Editor Melinda B. Buntin, PhD, discuss the effects of these provisions on patients with Aaron S. Kesselheim, MD, JD, MPH, of Harvard Medical School and Brigham and Women's Hospital. Related Content: New Reforms to Prescription Drug Pricing in the US Estimating Rebates and Other Discounts Received by Medicare Part D Estimation of the Share of Net Expenditures on Insulin Captured by US Manufacturers, Wholesalers, Pharmacy Benefit Managers, Pharmacies, and Health Plans From 2014 to 2018 Spending by the Centers for Medicare & Medicaid Services Before and After Confirmation of Benefit for Drugs Granted US Food and Drug Administration Accelerated Approval, 2012 to 2017 Improving Prescription Drug Affordability Through Regulatory Action

Electronic health records (EHRs) hold great promise to assist clinicians, but current versions are less user-friendly than ideal. JAMA Associate Editor Tracy Lieu, MD, MPH, spoke with Kevin B. Johnson, MD, MS, University of Pennsylvania, and William W. Stead, MD, Vanderbilt University Medical Center, about how to improve EHRs to protect cognitive attention and optimize their potential to provide cognitive support to health care professionals. Related Content: Making Electronic Health Records Both SAFER and SMARTER

In this Author Interview, JAMA Deputy Editor Gregory Curfman, MD, discusses the state of coronary artery bypass surgery in 2022 with E. Magnus Ohman, MD, from Duke University. The conversation emphasizes methods to preserve patency of saphenous vein bypass grafts, the subject of an article in the August 9, 2022, issue of JAMA. Dr Ohman wrote the accompanying Editorial. Related Content: Association of Dual Antiplatelet Therapy With Ticagrelor With Vein Graft Failure After Coronary Artery Bypass Graft Surgery Balancing the Risks and Benefits of Antiplatelet Therapy After Coronary Artery Bypass Graft Surgery

On August 3, 2022, the US Department of Health and Human Services released 2 major reports in response to a presidential memo calling for a whole-of-government response to the SARS-CoV-2 sequelae known as “Long COVID." JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, discusses these new reports and the research and support needed to address this pervasive health concern with HHS Assistant Secretary for Health Rachel Levine, MD. Recorded July 29, 2022. Related Content: Addressing the Long-term Effects of COVID-19 Association Between BNT162b2 Vaccination and Long COVID After Infections Not Requiring Hospitalization in Health Care Workers Long COVID: The US Federal Response (Video)

Interview with Lori Pbert, PhD, USPSTF member and coauthor of Behavioral Counseling Interventions to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Cardiovascular Disease Risk Factors: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Senior Editor Kristin L. Walter, MD, MS. Related Content: Behavioral Counseling Interventions to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Known Cardiovascular Disease Risk Factors Behavioral Counseling Interventions to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Cardiovascular Disease Risk Factors Behavioral Counseling Interventions to Promote a Healthy Diet and Physical Activity to Prevent CVD in Adults Without Risk Factors Implications of the New Recommendation on Behavioral Counseling Interventions to Promote Healthy Eating and Physical Activity Improving Behavioral Counseling for Primary Cardiovascular Disease Prevention Updated USPSTF Recommendations for Behavioral Counseling Interventions

Exercise limitation is a cardinal manifestation of heart failure with reduced ejection fraction (HFrEF), but it is not consistently improved by any of the current guideline-directed medical therapies. JAMA Deputy Editor Gregory Curfman, MD, discusses whether omecamtiv mecarbil can improve peak exercise capacity in patients with HFrEF with Gregory D. Lewis, MD, from Massachusetts General Hospital, and Mark H. Drazner, MD, MSc, from University of Texas Southwestern Medical Center. Related Content: Effect of Omecamtiv Mecarbil on Exercise Capacity in Chronic Heart Failure With Reduced Ejection Fraction: The METEORIC-HF Randomized Clinical Trial Omecamtiv Mecarbil as a Therapy for Heart Failure With Low Ejection Fraction

JAMA Associate Editor Preeti Malani, MD, MSJ, discusses the transmission, diagnosis, and treatment of monkeypox and the 2022 outbreak with Jeannette Guarner, MD, and Carlos del Rio, MD, both of the Division of Infectious Diseases at Emory University's School of Medicine. Related Content: Monkeypox in 2022—What Clinicians Need to Know What Is Monkeypox? What to Know About Monkeypox Global Monkeypox Outbreaks Spur Drug Research for the Neglected Disease

Patient safety is a national priority, but adverse events during hospitalization are hard to track and whether progress has been made over the past decade is unknown. JAMA Associate Editor Karen E. Joynt Maddox, MD, MPH, Washington University School of Medicine, discusses recent findings demonstrating decreases in hospital chart-abstracted adverse events and what's next in patient safety in the wake of COVID-19, with Mark Metersky, MD, University of Connecticut Health Center, and Peter Pronovost, MD, PhD, University Hospitals, Shaker Heights, Ohio. Related Content: Trends in Adverse Event Rates in Hospitalized Patients, 2010-2019 Improvements in Hospital Adverse Event Rates: Achieving Statistically Significant and Clinically Meaningful Results

In July 2022, Kirsten Bibbins-Domingo, PhD, MD, MAS, took on a new role as the 17th editor in chief of JAMA and the JAMA Network. In conversation with Nobel laureate Harold Varmus, MD, Bibbins-Domingo discusses her research background, approaches to leadership in health care, and the critical role that journals play in communication about public health and science. Related Content: The Urgency of Now and the Responsibility to Do More—My Commitment for JAMA and the JAMA Network A Conversation With Dr Kirsten Bibbins-Domingo, JAMA's New Editor in Chief (video) A Conversation With Dr Kirsten Bibbins-Domingo, JAMA's New Editor in Chief (audio)

Observational data suggest that the risk of certain types of cancer may be increased in individuals with obesity and that this risk may be lower after bariatric surgery. JAMA Deputy Editor Gregory Curfman, MD, explores this in detail with Steven Nissen, MD, an author of a JAMA study on this topic, and Anita Courcoulas, MD, MPH, author of an accompanying editorial. Related Content: Association of Bariatric Surgery With Cancer Risk and Mortality in Adults With Obesity Bariatric Surgery and Cancer Risk

Interview with John B Wong, MD, USPSTF member and coauthor of Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Deputy Editor Mary M. McDermott, MD. Related Content: Multivitamins and Supplements—Benign Prevention or Potentially Harmful Distraction? Patient Information: Vitamins and Minerals to Prevent Cardiovascular Disease and Cancer

Interview with Lisa Rotenstein, MD, MBA, author of A Learning Health System Agenda for Organizational Approaches to Enhancing Occupational Well-being Among Clinicians, and Clyde W. Yancy, MD, author of Resident Physician Wellness Postpandemic: How Does Healing Occur?. Hosted by JAMA Associate Editor Anne Cappola, MD.

Interview with Katrina Erika Donahue, MD, MPH, coauthor of Screening for Primary Open-Angle Glaucoma: US Preventive Services Task Force Recommendation Statement, and  Screening for Impaired Visual Acuity in Older Adults: US Preventive Services Task Force Recommendation Statement Hosted by JAMA Deputy Editor Mary M. McDermott, MD. Related Content: USPSTF Review: Screening for Glaucoma in Adults USPSTF Review: Screening for Impaired Visual Acuity in Older Adults Patient Information: Screening for Primary Open-Angle Glaucoma Screening for Impaired Visual Acuity in Older Adults Patient Information: Screening for Impaired Visual Acuity in Older Adults Screening for Glaucoma

As the White House's COVID-19 Response Coordinator, Ashish Jha, MD, MPH, plays a critical role in the federal government's continued response to the pandemic. In this Q&A with JAMA Associate Editor Preeti Malani, MD, Jha details current thinking and federal planning around additional boosters, testing trends, and treatment for COVID-19. Related Content: New White House COVID-19 Leader on What's Next Q&A With White House COVID-19 Response Coordinator Ashish Jha

Interview with Katrina E. Donahue, MD, MPH, USPSTF member and coauthor of Screening for Chronic Obstructive Pulmonary Disease: US Preventive Services Task Force Reaffirmation Recommendation Statement. Hosted by JAMA Senior Editor Kristin Walter, MD. Related Content: USPSTF Review: Screening for Chronic Obstructive Pulmonary Disease Screening for Chronic Obstructive Pulmonary Disease: Challenges and Opportunities USPSTF Recommendation: Screening for Chronic Obstructive Pulmonary Disease Patient Information: Screening for Chronic Obstructive Pulmonary Disease

After serving as commissioner of the US Food and Drug Administration (FDA) under President Obama, Robert M. Califf, MD, recently returned to the role, overseeing a critical federal agency that regulates food, drugs, therapeutics, and medical devices in the US. In a wide-ranging discussion with JAMA Deputy Editor Gregory Curfman, MD, Califf discusses COVID-19 vaccine modifications, the FDA's approach to evaluating evidence, and efforts to combat health misinformation. Recorded April 26, 2022. Related Content:

Interview with John B. Wong, MD, USPSTF member and coauthor of Aspirin Use for Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Deputy Editor Gregory Curfman, MD. Related Content: Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement Should Patients Take Aspirin for Primary Cardiovascular Prevention? USPSTF Review: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the US Preventive Services Task Force Patient Information: Use of Aspirin to Prevent Cardiovascular Disease Whom to Treat for Primary Prevention of Atherosclerotic Cardiovascular Disease

Misinformation about COVID-19 (such as around vaccines, masks, and ineffective drugs) has circulated widely during the pandemic, and much of this misinformation is protected by the Free Speech Clause of the First Amendment. Professor of Surgery and Perioperative Care and Professor of Law William M. Sage, MD, JD, from the University of Texas at Austin, is interviewed in this JAMA podcast. Related Content: Reducing “COVID-19 Misinformation” While Preserving Free Speech

Electrocardiographic markers of atrial myopathy are associated with dementia, but it is unclear whether 2-dimensional echocardiographic––defined LA function and size are associated with dementia. JAMA Senior Editor Philip Greenland, MD, discusses study findings with Wendy Wang, MPH, and Lin Yee Chen, MD, authors of Association of Echocardiographic Measures of Left Atrial Function and Size With Incident Dementia

As the largest public insurance program in the US, Medicare has an outsize influence in how many people in the US access and receive health care. Recently appointed Director of Center for Medicare Meena Seshamani, MD, PhD, joins JAMA Associate Editor Karen Joynt Maddox, MD, for a discussion of equitable, patient-centered approaches to health care delivery, and how her own experiences as a physician have illuminated how she leads the program. Related Content: Center for Medicare Director Envisions Holistic Approach to Health Care Leading Medicare: Q&A With Medicare Director Meena Seshamani Health System Factors Related to Overuse of Health Services in Medicare

Interview with Lori Pbert, PhD, USPSTF member and coauthor of Screening for Eating Disorders in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement

Interview with Gbenga Ogedegbe, MD, MPH, USPSTF member and coauthor of Screening for Atrial Fibrillation: US Preventive Services Task Force Recommendation Statement. Hosted by Gregory Curfman, MD.

Three members of President Biden's former COVID-19 Advisory Board—Luciana Borio, MD, Ezekiel Emanuel, MD, PhD, and Mike Osterholm, PhD—discuss their recent JAMA Viewpoints, providing their ideas on strategies for public health as COVID-19 transitions from pandemic to endemic. Hosted by JAMA Associate Editor Preeti Malani, MD. Related Content: A National Strategy for the “New Normal” of Life With COVID A National Strategy for COVID-19—Testing, Surveillance, and Mitigation Strategies A National Strategy for COVID-19 Medical Countermeasures Former Biden-Harris Transition Advisors Propose a New National Strategy for COVID-19 Public Health in an Era of Endemic COVID-19 (video)

Former CDC Executive Secretariat of the Advisory Committee on Immunization Practices Amanda Cohn, MD, joins JAMA Associate Editor Preeti Malani, MD, for the latest on the need for vaccination and boosters, vaccine misinformation, and tackling the pandemic from a global perspective. Recorded January 6, 2022. Related Content: One Year of COVID-19 Vaccines: A Shot of Hope, a Dose of Reality COVID-19 Vaccines Have Been Available in the US for More Than a Year—What's Been Learned and What's Next? COVID-19 CDC Update – Early January 2022

Interview with Michael Cabana, MD, USPSTF member and coauthor of Screening and Interventions to Prevent Dental Caries in Children Younger Than 5 Years: US Preventive Services Task Force Recommendation Statement. Related Content:

Infectious disease experts Adam Lauring, MD, PhD, and Carlos del Rio, MD, join JAMA Associate Editor Preeti Malani, MD, MSJ, for a discussion of the newly emerged Omicron variant, the potential for a 2021-2022 "twindemic" with flu, and the latest COVID-19 clinical updates. Recorded December 1, 2021. Related content: Omicron Has Reached the US—Here's What Infectious Disease Experts Know About the Variant COVID-19 Update: Omicron Variant