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Human immunity wanes as we age, but what if it could be restored? A UT Health San Antonio researcher who studies the thymus has confirmed that a certain protein can restore its size and function in mice, leading to a larger and more diverse T cell population that more closely resembles the T cells of youth.
The rate of cancer and cancer malignancy differ greatly among mammalian species. The placental – maternal interface is also highly variable between placental mammals. This lecture will discuss recent advances that suggest that there is a causal connection between the evolution of placental biology and the biology and rate of cancer malignancy. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40694]
Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]
Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]
Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]
Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]
Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]
Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]
Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]
In this episode of Skin Anarchy, host Dr. Ekta Yadav is joined by Dr. Stacie Stephenson, a leading voice in functional and integrative medicine, for a powerful conversation that reframes how we think about skin health. Rather than isolating skin concerns from the rest of the body, Dr. Stacie emphasizes a systems-based approach that connects the dots between stress, inflammation, gut health, and chronic conditions like acne and autoimmune disease.Dr. Stacie shares her remarkable journey from Olympic-level figure skating to becoming a disruptor in modern medicine—after personal health challenges led her to seek deeper answers beyond traditional care. Together, she and Dr. Ekta unpack the philosophy of functional medicine, spotlighting its focus on root causes, not just symptoms.They explore acne as a case study in how conventional treatments often overlook gut dysfunction, food sensitivities, and long-term microbiome damage. Dr. Stacie also weighs in on the rise of GLP-1 medications like Ozempic and Wegovy—highlighting their promise, their risks, and the psychological dimensions of weight and wellness.This episode is both a masterclass and a mindset shift. Listeners will walk away with a clearer understanding of how to partner with their body—and their practitioner—to personalize their path to better health. Whether you're managing a stubborn skin condition or exploring holistic healing, this conversation may offer the insight you've been searching for.CHAPTERS:(0:00) Introduction to Dr. Stacie Stephenson(1:16) Dr. Stacie's Journey into Functional and Integrative Medicine(4:31) The Influence of Athletic Experience on Dr. Stacie's Career(7:25) Discovering Functional Medicine and Early Career Challenges(9:26) Key Pillars of Functional Medicine and Its Application(12:12) The Role of Gut Health and Detoxification in Functional Medicine(16:04) Understanding Preventative Medicine and the Importance of Personal Health Awareness(19:43) Dr. Stacie's Thoughts on Acne and Its Root Causes(27:01) The GLP-1 Drugs: Benefits and Concerns on Long-Term UseTo learn more about Dr. Stacie Stephenson, visit her website and social media.Don't forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform.Reach out to us through email with any questions.Sign up for our newsletter!Shop all our episodes and products mentioned through our ShopMy Shelf! Hosted on Acast. See acast.com/privacy for more information.
Amy MacIver is joined by Professor Elizabeth Mayne, a specialist haematologist and immunopathologist at the University of Cape Town, to unpack new research revealing how our immune system is influenced by light. A recent study from the University of Auckland found that neutrophils — the body’s most abundant white blood cells — are more effective at killing bacteria during the day, thanks to an internal, light-sensitive circadian clock. Presenter John Maytham is an actor and author-turned-talk radio veteran and seasoned journalist. His show serves a round-up of local and international news coupled with the latest in business, sport, traffic and weather. The host’s eclectic interests mean the program often surprises the audience with intriguing book reviews and inspiring interviews profiling artists. A daily highlight is Rapid Fire, just after 5:30pm. CapeTalk fans call in, to stump the presenter with their general knowledge questions. Another firm favourite is the humorous Thursday crossing with award-winning journalist Rebecca Davis, called “Plan B”. Thank you for listening to a podcast from Afternoon Drive with John Maytham Listen live on Primedia+ weekdays from 15:00 and 18:00 (SA Time) to Afternoon Drive with John Maytham broadcast on CapeTalk https://buff.ly/NnFM3Nk For more from the show go to https://buff.ly/BSFy4Cn or find all the catch-up podcasts here https://buff.ly/n8nWt4x Subscribe to the CapeTalk Daily and Weekly Newsletters https://buff.ly/sbvVZD5 Follow us on social media: CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.
In this episode, Dr. April Spencer discusses the evolving landscape of breast cancer, particularly among younger women, and the various lifestyle factors contributing to this trend. She emphasizes the importance of stress management, self-care, and setting boundaries to improve women's health outcomes. This discussion also highlights: The emotional and physical challenges women face during a breast cancer diagnosis A multifaceted approach to breast cancer care, emphasizing the importance of support systems, the need for women to advocate for themselves, and the role of integrative medicine The significance of choosing the right medical team How healthcare providers are impacted by burnout Recent updates on mammogram guidelines and hormone therapy considerations for women Dr. Spencer's advice for those facing a breast cancer diagnosis Show Notes:Learn more about Dr. Spencer and follow her on Instagram @dr.aprilspencer! Become a DUTCH Provider today to get access to free educational resources, expert clinical support, peer-reviewed and validated research, and comprehensive patient reports.
Menstruation is the cyclical shedding of the endometrium triggered by falling progesterone levels. Menstruation is a rare trait found in less than 2% of mammals and likely evolved independently at least 4 times. Why do some mammals menstruate while most do not? The leading hypothesis is that menstruation occurs as a nonadaptive consequence of spontaneous decidualization of the endometrium, which evolved to increase biosensoring of embryo quality. While the trait of spontaneous decidualization (and as a byproduct, menstruation) was likely shaped by natural selection, menstruation also disposes women to conditions such as endometriosis, pre-menstrual syndrome, and bleeding disorders, especially in the contemporary context. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40693]
Menstruation is the cyclical shedding of the endometrium triggered by falling progesterone levels. Menstruation is a rare trait found in less than 2% of mammals and likely evolved independently at least 4 times. Why do some mammals menstruate while most do not? The leading hypothesis is that menstruation occurs as a nonadaptive consequence of spontaneous decidualization of the endometrium, which evolved to increase biosensoring of embryo quality. While the trait of spontaneous decidualization (and as a byproduct, menstruation) was likely shaped by natural selection, menstruation also disposes women to conditions such as endometriosis, pre-menstrual syndrome, and bleeding disorders, especially in the contemporary context. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40693]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
Menstruation is the cyclical shedding of the endometrium triggered by falling progesterone levels. Menstruation is a rare trait found in less than 2% of mammals and likely evolved independently at least 4 times. Why do some mammals menstruate while most do not? The leading hypothesis is that menstruation occurs as a nonadaptive consequence of spontaneous decidualization of the endometrium, which evolved to increase biosensoring of embryo quality. While the trait of spontaneous decidualization (and as a byproduct, menstruation) was likely shaped by natural selection, menstruation also disposes women to conditions such as endometriosis, pre-menstrual syndrome, and bleeding disorders, especially in the contemporary context. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40693]
Menstruation is the cyclical shedding of the endometrium triggered by falling progesterone levels. Menstruation is a rare trait found in less than 2% of mammals and likely evolved independently at least 4 times. Why do some mammals menstruate while most do not? The leading hypothesis is that menstruation occurs as a nonadaptive consequence of spontaneous decidualization of the endometrium, which evolved to increase biosensoring of embryo quality. While the trait of spontaneous decidualization (and as a byproduct, menstruation) was likely shaped by natural selection, menstruation also disposes women to conditions such as endometriosis, pre-menstrual syndrome, and bleeding disorders, especially in the contemporary context. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40693]
Menstruation is the cyclical shedding of the endometrium triggered by falling progesterone levels. Menstruation is a rare trait found in less than 2% of mammals and likely evolved independently at least 4 times. Why do some mammals menstruate while most do not? The leading hypothesis is that menstruation occurs as a nonadaptive consequence of spontaneous decidualization of the endometrium, which evolved to increase biosensoring of embryo quality. While the trait of spontaneous decidualization (and as a byproduct, menstruation) was likely shaped by natural selection, menstruation also disposes women to conditions such as endometriosis, pre-menstrual syndrome, and bleeding disorders, especially in the contemporary context. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40693]
Menstruation is the cyclical shedding of the endometrium triggered by falling progesterone levels. Menstruation is a rare trait found in less than 2% of mammals and likely evolved independently at least 4 times. Why do some mammals menstruate while most do not? The leading hypothesis is that menstruation occurs as a nonadaptive consequence of spontaneous decidualization of the endometrium, which evolved to increase biosensoring of embryo quality. While the trait of spontaneous decidualization (and as a byproduct, menstruation) was likely shaped by natural selection, menstruation also disposes women to conditions such as endometriosis, pre-menstrual syndrome, and bleeding disorders, especially in the contemporary context. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40693]
In today’s episode, I sit down with returning guest Dr. Scott Sherr, a board-certified internal medicine physician known for his work in hyperbaric medicine, innovative nootropics, and his role as Chief Operating Officer of Troscriptions, where he developed the infamous precision-dosed “smurf mouth” methylene blue troches (use code BEN to save 10%). In this conversation, we dive into the science and potential of one of the most intriguing compounds in advanced wellness: cordycepin. Dr. Scott Sherr is a Board-Certified Internal Medicine Physician Certified to Practice Health Optimization Medicine (HOMe), a specialist in Hyperbaric Oxygen Therapy (HBOT), and COO of Troscriptions. His clinical telepractice includes HOMe as its foundation alongside an integrative approach to HBOT that includes cutting-edge and dynamic HBOT protocols, comprehensive testing (using the HOMe framework), targeted supplementation, personal practices, synergistic technologies (new, ancient, psychedelic), and more. Full show notes: https://bengreenfieldlife.com/sherr Episode Sponsors: Just Thrive: For a limited time, you can save 20% off a 90-day bottle of Just Thrive Probiotic and Just Calm at justthrivehealth.com/ben with promo code BEN. That’s like getting a month for FREE—take control today with Just Thrive! LVLUP Health: I trust and recommend LVLUP Health for your peptide needs as they third-party test every single batch of their peptides to ensure you’re getting exactly what you pay for and the results you’re after! Head over to lvluphealth.com/BGL and use code BEN15 for a special discount on their game-changing range of products. Calroy: Head on over to calroy.com/ben and save over $50 when you purchase the Vascanox (a breakthrough product providing nitric oxide support for up to 24 hours with a single dose) and Arterosil (a premier supplement to support the endothelial glycocalyx—the fragile inner lining of the entire vascular system) bundle at calroy.com/ben. Plus, you'll receive a free canister of 2-in-1 Nitric Oxide Test Strips with a 3-pack bundle purchase. Sunlighten: Discover the ultimate efficiency in wellness with the Sunlighten Solo System, a compact, portable far infrared sauna designed to detoxify, reduce stress, improve sleep, and enhance heart health—all while fitting seamlessly into your daily routine. Save $600 or more today and start biohacking your mind, body, and spirit at get.sunlighten.com/ben! BIOptimizers Mushroom Breakthrough: Mushroom Breakthrough combines four powerful mushrooms with collagen to enhance brain function, promote healthier skin, hair, and nails, and strengthen your immune system. Go to bioptimizers.com/ben now and enter promo code BEN10 to get 10% off any order.See omnystudio.com/listener for privacy information.
The episode opens with candid childhood memories of vaccines—then veers into a bigger question: Have we placed too much blind faith in medicine? The hosts reflect on their different upbringings, training, and the shocking fallout they've seen in their practices. They dissect the fallout from COVID—how it silenced dissent, reshaped medical narratives, and forced patients and providers into black-and-white camps.Together, they examine the erosion of trust in institutions, the marketing of fear, and how both allopathic and holistic medicine have lost their way. From the overuse of antibiotics to the rise of $25,000 wellness scans, they challenge listeners to think critically, not reactively. But beneath it all is a quiet call to return to balance—trusting the body, embracing questions, and choosing life over fear.About the ShowMD/DC is where medical meets meaningful—and where respectful disagreement leads to discovery. Hosted by Dr. Tim Hindmarsh, a board-certified physician, and his chiropractor co-host, this show brings together two healing professions that don't always see eye to eye.With humor, humility, and a healthy dose of skepticism, they unpack the big questions in medicine, wellness, and culture. No scripts. No tribalism. Just honest conversations about what's helping, what's hurting, and how we can all get back on the highway to health.Whether you're an MD, DC, RN, or just someone trying to make sense of modern healthcare—you're welcome here.Our Advice!Everything in this podcast is for educational purposes only. It does not constitute the practice of medicine and we are not providing medical advice. No Physician-patient relationship is formed and anything discussed in this podcast does not represent the views of our employers. The Fine Print!All opinions expressed by the hosts or guests in this episode are solely their opinion and are not to be used as specific medical advice. The hosts, May and Tim Hindmarsh MD, BS Free MD LLC, or any affiliates thereof are not under any obligation to update or correct any information provided in this episode. The guest's statements and opinions are subject to change without notice.Thanks for joining us! You are the reason we are here. If you have questions, reach out to us at doc@bsfreemd.com or find Tim and I on Facebook and IG.Please check out our every growing website as well at bsfreemd.com (no www) GET SOCIAL WITH US!We're everywhere here: @bsfreemd
In this episode, Dr. Jockers and Steve Wright explain why many people stay inflamed even after removing toxins and eating clean. The real issue isn't exposure—it's lost immune tolerance, and the solution is rebuilding resilience. You'll learn about the five gut defense layers that regulate your immune system. Fixing oxygen balance, mucus layers, and gut cell mitochondria is key to restoring proper function. They also cover how para-probiotics—dead bacteria—can retrain an overactive immune response. If you're sensitive to foods, histamines, or your environment, this episode lays out what to do next. In This Episode: 00:00 Introduction to Early Childhood Exposure and Health Benefits 02:59 Interview with Steve Wright: Retraining a Broken Gut Immune System 05:26 Understanding the Immune System and Its Connection to the Gut 08:02 Challenges in Modern Health and the Importance of Gut Resilience 10:50 The Role of the Gut in Immune Function and Balance 23:04 Layers of the Gut and Their Functions 26:36 Mitochondria and Gut Health 27:59 Impact of Antibiotics on Gut Microbiome 28:47 The Role of Stomach Acid in Digestion 31:51 Resetting Gut Health 33:27 Individualized Diets and Food Tolerance 36:44 Repairing Gut Health: Steps and Supplements 40:32 Para Probiotics: An Overview 44:51 Healthy Gut Products and Protocols 48:46 Final Thoughts and Recommendations Still cooking with seed oils? That could be fueling inflammation. I've switched to Paleovalley's 100% grass-fed beef tallow—it's rich in CLA, packed with flavor, and stable at high heat. It's one of the cleanest, most nutrient-dense fats you can cook with. Head to paleovalley.com/jockers and use code JOCKERS for 15% off your order. Heartburn doesn't mean you have too much stomach acid—it usually means you don't have enough. That's why I recommend Just Thrive's Digestive Bitters. They help ignite stomach acid, enzymes, and bile so you can finally break down food the way you're supposed to. Go to justthrivehealth.com and use code JOCKERS to save 20%. "Healing the gut isn't just about avoiding toxins—it's about building resilience." ~ Dr. Jockers Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Get 15% off Paleovalley Beef Tallow: paleovalley.com/jockers – Use code JOCKERS Save 20% on Just Thrive Digestive Bitters: justthrivehealth.com – Use code JOCKERS Connect with Steve Wright: Website: https://healthygut.com/ Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
This episode was recorded in Reno, Nevada, during the 2025 Western Dairy Management Conference. The panel discusses their individual experiences with outbreaks in different states. Beth talks about her group's microbial surveillance technology they used to compare rectal swabs from positive and non-positive herds. They noted elevations in specific virulent E. coli, Salmonella spp., and Clostridium perfringens in the HPAI-positive herds. Enrique noted that in California, the outbreak began in the South Valley during periods of heat stress, which exacerbated symptoms. He also felt that some dairies panicked a little and moved cows too much, which did not help. In the North Valley, the outbreak happened in cooler weather, and dairies purposefully did not move cows out of their pens and provided supportive therapy within the pen. (5:25)Dr. Schcolnik emphasized making sure i's are dotted and t's are crossed in your nutrition program to help manage through an outbreak. The immune system is an obligate glucose utilizer, so energy is key, as are protein and trace minerals. He noted they also added binders to diets, and either probiotics or double doses of yeast to keep the rumen healthy. Decreasing intake is a big symptom, so he recommends vitamin B supplementation to stimulate appetite. (12:30)The panel discusses how the Texas and California outbreaks differed from one another, including heat stress, recovery in milk production after infection, bird migration and cattle movement. Enrique notes that in California, it seemed like transmission was going downwind. Animal movement, wild birds and milk trucks were also implicated. (14:31)Several companies are investing in vaccine development, but the virus mutation is a challenge. Dr. Spencer wonders if the vaccine will end up resembling the human flu vaccine where you hope to target the general structure of the virus to reduce impact. The panel talks about natural immunity and how cows will be impacted in the lactation after they were ill. Dr. Schcolnik has observed that a percentage of cows who were dry during the outbreak aren't performing as well after freshening. He hypothesizes this could be due to mammary cell death during infection, as the virus lyses the cell as it exits the cell. (24:41)The panel discusses practical recommendations for dairy producers to prepare for or help mitigate during an outbreak. Biosecurity is key. Vaccines are hopefully on the way, but until then, minimizing cattle movements within the herd, post-dipping cows as soon as possible after the machine falls off and minimizing splashing of milk are all good practices. The panel looks forward to more research about all the different ways the virus transmits. They're also eager to learn more about treatment plans and what has worked for different dairies regarding giving fluids, altering rations, boosting the immune system, managing co-infections and impacts on calves and heifers. (29:18)Lastly, panelists share their take-home thoughts. (37:33)Scott invites the audience to Bourbon and Brainiacs at ADSA in Louisville - a bourbon tasting with all your favorite professors! Sign up here: https://balchem.com/anh/bourbon/Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table. If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.
This week we have re-posting a brief insight to the fact that stress can play havoc on the immune system and we hope to have a new guest soon to discuss this weighty problem. If you are a member of the health care community and would like to be a guest on our show to discuss how stress affects the immune system, please drop us a line at PodcastDX@yahoo.com. Remember chronic stress = excessive cortisol and too much cortisol = a host of medical ailments. Poor sleep Cortisol levels are supposed to drop at nighttime, allowing your body to relax and recharge. But if your cortisol levels are too high, you might notice that, even if you've been tired all day, you get a second wind right around bedtime. Then you toss and turn all night – and feel tired again the next day. Over time, high levels of cortisol deplete the adrenal glands and predispose you to chronic fatigue. So if you feel like your get up and go got up and went, you're probably stressed. You're gaining weight, especially around your abdomen, even when you eat well and exercise. Cortisol tends to make you thick around the middle, even when you're doing everything “right.” You catch colds and other infections easily. Cortisol deactivates your body's natural self-repair mechanisms, which means that your immune system which is perfectly designed by nature to keep you healthy goes caput, leaving you vulnerable to every cootie you encounter. You crave unhealthy foods. Cortisol raises your blood sugar, putting you at risk of diabetes. High glucose levels then bump up your insulin levels, which then drop your blood sugar it's a vicious cycle! You experience backaches and headaches. When your cortisol levels are high over a long period of time, your adrenal glands start to get depleted. This raises prolactin levels, increasing the body's sensitivity to pain, such as backaches and muscle aches. Excessive cortisol also hypersensitizes the brain to pain, such that even the slightest twinge can excite the nerves of the brain, causing headaches. Lo-Libido Consider cortisol the anti-Viagra. When stress hormones are high, libido-inducing hormones like testosterone drop. GI Issues. Your gastrointestinal system is very sensitive to stress hormones like cortisol. You might experience nausea, heartburn, abdominal cramps, diarrhea, or constipation as a result of too many stress hormones. Emotional Problems. Cortisol and epinephrine can lead to jitters, nervous stomach, feelings of panic, even paranoia. High levels of cortisol suppress production of serotonin, and next thing you know, you're awash in doom and gloom. Chronic High Cortisol=Adrenal Fatigue When your cortisol levels are bumped up, day after day, your adrenal glands, responsible for the production of cortisol, get worn out. Precursor hormones required for cortisol production get depleted. This could result in full blown adrenal collapse. (Credits: Dr Lissa Rankin M.D. https://binged.it/3xgOpDc )
Episode Highlights With MegWhat histamine is and how it can be causing symptoms you may not even realizeThe different parts of the immune system and how they're important to understandLink to stomach acid and digestionWhat's happening when histamine is out of balanceSometimes anxiety and insomnia might be the only responses and symptoms of histamine issuesWhy histamine purposefully causes inflammation We have four different types of histamine receptors in our bodiesHow hormone shifts can affect histamine levels and vice versaEstrogen dominance and the link to histamine, plus times of the month a woman is most likely to see hormone related histamine issuesWhat mast cell activation syndrome is and how to address itTesting and diagnostic criteria for histamine issuesHigh histamine foods and how to try a low histamine diet First steps to take if you suspect histamine issuesResources MentionedThe Essential Guide to Histamine Intolerance - Free resourceDr. Meg's website and her Instagram
Pressures of life on Earth experienced by our ancestors – as multicellular beings, as hosts to parasites, and as home to microbes – shaped the evolved structure and function of our immune systems. Some of the traits favored by natural selection have conferred resistance against infections while opening vulnerabilities to autoimmune diseases. I will illustrate why analysis of the deep-time origins of mammalian immune systems reveals general principles of optimal defense and helps to explain why hosts are so profoundly variable in their susceptibility to infectious and inflammatory diseases. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40692]
Pressures of life on Earth experienced by our ancestors – as multicellular beings, as hosts to parasites, and as home to microbes – shaped the evolved structure and function of our immune systems. Some of the traits favored by natural selection have conferred resistance against infections while opening vulnerabilities to autoimmune diseases. I will illustrate why analysis of the deep-time origins of mammalian immune systems reveals general principles of optimal defense and helps to explain why hosts are so profoundly variable in their susceptibility to infectious and inflammatory diseases. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40692]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
Pressures of life on Earth experienced by our ancestors – as multicellular beings, as hosts to parasites, and as home to microbes – shaped the evolved structure and function of our immune systems. Some of the traits favored by natural selection have conferred resistance against infections while opening vulnerabilities to autoimmune diseases. I will illustrate why analysis of the deep-time origins of mammalian immune systems reveals general principles of optimal defense and helps to explain why hosts are so profoundly variable in their susceptibility to infectious and inflammatory diseases. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40692]
Pressures of life on Earth experienced by our ancestors – as multicellular beings, as hosts to parasites, and as home to microbes – shaped the evolved structure and function of our immune systems. Some of the traits favored by natural selection have conferred resistance against infections while opening vulnerabilities to autoimmune diseases. I will illustrate why analysis of the deep-time origins of mammalian immune systems reveals general principles of optimal defense and helps to explain why hosts are so profoundly variable in their susceptibility to infectious and inflammatory diseases. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40692]
Pressures of life on Earth experienced by our ancestors – as multicellular beings, as hosts to parasites, and as home to microbes – shaped the evolved structure and function of our immune systems. Some of the traits favored by natural selection have conferred resistance against infections while opening vulnerabilities to autoimmune diseases. I will illustrate why analysis of the deep-time origins of mammalian immune systems reveals general principles of optimal defense and helps to explain why hosts are so profoundly variable in their susceptibility to infectious and inflammatory diseases. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40692]
Pressures of life on Earth experienced by our ancestors – as multicellular beings, as hosts to parasites, and as home to microbes – shaped the evolved structure and function of our immune systems. Some of the traits favored by natural selection have conferred resistance against infections while opening vulnerabilities to autoimmune diseases. I will illustrate why analysis of the deep-time origins of mammalian immune systems reveals general principles of optimal defense and helps to explain why hosts are so profoundly variable in their susceptibility to infectious and inflammatory diseases. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40692]
Broadcast from KSQD, Santa Cruz on 5-30-2024 and 5-29-2925: Cognitive errors in medicine dismissing unusual presentations as psychological A case of Pediatric Autoimmune Neuropsychiatric disorders Associated with Streptococcal Infections (PANDAS) Anti-NMDA receptor encephalitis causing psychiatric symptoms Failures of genetic research to identify causes Need for integrating neurology and psychiatry; Importance of testing for antibodies and using MRI scans Detailed explanation of immune tolerance, peripheral tolerance, and the phenomenon of molecular mimicry in diseases like multiple sclerosis and celiac disease Importance of addressing root causes rather than just symptoms Historical context and current advancements in treating autoimmune diseases like type 1 diabetes, lupus, and multiple sclerosis using reprogrammed immune cells and iron oxide nanoparticles Explanation of how the liver filters blood and helps establish immune tolerance by processing cellular debris and antigens Advances in engineering regulatory T cells to target specific disease sites and calm inflammatory responses Exploration of new diagnostic tools and the potential of AI in understanding complex psychiatric conditions Detection of colds and other diseases by analysis of voice frequency patterns
Biohacking is a simple concept - give your body the things it naturally needs to heal itself. While we may see these complicated strategies that some influencers are promoting or the idea of taking a large amount of supplements in order to create a healthy body, Dr. Khalsa reminds us that many of the things we need are free to us in the natural world. We simply need to change our daily behavior to activate the healing process.Dr. Har Hari Khalsa, Holistic Practitioner, is a highly experienced holistic practitioner who has been assisting people on their healing journey since 1988. At Transformational Healing Universe in the Pico-Robertson neighborhood of Los Angeles, California, Har Hari focuses on medical, and yogic healing. He specializes in several techniques and fields of healing, including adjustments, Kundalini yoga and meditation, the Wim Hof Method, and Summus Laser treatments (formerly K-Laser™).For more information visit www.transformationalhealinguniverse.com, Instagram @drharhari, or Facebook @transformationalhealinguniverse Visit ConfidenceThroughHealth.com to find discounts to some of our favorite products.Follow me via All In Health and Wellness on Facebook or Instagram.Find my books on Amazon: No More Sugar Coating: Finding Your Happiness in a Crowded World and Confidence Through Health: Live the Healthy Lifestyle God DesignedProduction credit: Social Media Cowboys
The human body has traits that evolved at different times, from 1.5 billion to 2 million years ago, each bringing health benefits and risks. Multicellularity enabled organs and cancer. The immune system defends us but can cause inflammation. Breastfeeding supports infant health but relates to breast cancer risk. Menstruation and invasive placentas improved reproduction but led to pain and cancer risks. Human-specific traits like bipedalism and aging brought new issues like back pain and childbirth problems. Hair loss and sweat glands helped us stay cool but increased skin cancer risk. Our hunter-gatherer past shaped our microbiome and health, but also made us prone to modern diseases from lifestyle changes. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40701]
Cancer is normal development spun out of control. It is the great plasticity and power of development, without the overarching controls that guide normal development toward an integrated adult form. Instead, whenever a newly developed kind of tissue acquires the ability to survive, grow, and resist control, there is nothing to stop it. That may be why normal adult cells are often terminally differentiated into a restricted cellular program. And it may be why wound healing, which releases the restricted cellular program and powerfully plastic tissue remodeling, is so tightly regulated and, when dysregulated, so often associates with cancer. With regard to evolutionary history, humans develop differently from their ape ancestors, and their lifestyle causes them to suffer different kinds of tissue damage. Those differences in development and wound healing likely led to new aspects of cancer disease over human history. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40691]
The human body has traits that evolved at different times, from 1.5 billion to 2 million years ago, each bringing health benefits and risks. Multicellularity enabled organs and cancer. The immune system defends us but can cause inflammation. Breastfeeding supports infant health but relates to breast cancer risk. Menstruation and invasive placentas improved reproduction but led to pain and cancer risks. Human-specific traits like bipedalism and aging brought new issues like back pain and childbirth problems. Hair loss and sweat glands helped us stay cool but increased skin cancer risk. Our hunter-gatherer past shaped our microbiome and health, but also made us prone to modern diseases from lifestyle changes. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40701]
Cancer is normal development spun out of control. It is the great plasticity and power of development, without the overarching controls that guide normal development toward an integrated adult form. Instead, whenever a newly developed kind of tissue acquires the ability to survive, grow, and resist control, there is nothing to stop it. That may be why normal adult cells are often terminally differentiated into a restricted cellular program. And it may be why wound healing, which releases the restricted cellular program and powerfully plastic tissue remodeling, is so tightly regulated and, when dysregulated, so often associates with cancer. With regard to evolutionary history, humans develop differently from their ape ancestors, and their lifestyle causes them to suffer different kinds of tissue damage. Those differences in development and wound healing likely led to new aspects of cancer disease over human history. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40691]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
Cancer is normal development spun out of control. It is the great plasticity and power of development, without the overarching controls that guide normal development toward an integrated adult form. Instead, whenever a newly developed kind of tissue acquires the ability to survive, grow, and resist control, there is nothing to stop it. That may be why normal adult cells are often terminally differentiated into a restricted cellular program. And it may be why wound healing, which releases the restricted cellular program and powerfully plastic tissue remodeling, is so tightly regulated and, when dysregulated, so often associates with cancer. With regard to evolutionary history, humans develop differently from their ape ancestors, and their lifestyle causes them to suffer different kinds of tissue damage. Those differences in development and wound healing likely led to new aspects of cancer disease over human history. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40691]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
The human body has traits that evolved at different times, from 1.5 billion to 2 million years ago, each bringing health benefits and risks. Multicellularity enabled organs and cancer. The immune system defends us but can cause inflammation. Breastfeeding supports infant health but relates to breast cancer risk. Menstruation and invasive placentas improved reproduction but led to pain and cancer risks. Human-specific traits like bipedalism and aging brought new issues like back pain and childbirth problems. Hair loss and sweat glands helped us stay cool but increased skin cancer risk. Our hunter-gatherer past shaped our microbiome and health, but also made us prone to modern diseases from lifestyle changes. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40701]
In this episode of Accelerated Health with Sara Banta, I'm joined by Ed Harrold—a leading expert in breathwork and performance coaching—to explore the powerful connection between your brain, heart, and gut, and how misalignment in these systems could be silently sabotaging your health, energy, and mental clarity.We explore:
This week, we are taking a closer look at equine sarcoids. Equine sarcoids are a common issue that can be concerning for horse owners. These skin growths are neither serious nor life-threatening, but they can be unsightly and sometimes tricky to manage. They tend to vary in appearance and location, and in some cases, can go unnoticed until they become more visibly pronounced.What Are Equine Sarcoids?Sarcoids are skin tumors that account for 36 to 40% of equine tumors. They can be flat, raised, crusty, weepy, or ulcerated, and can grow and spread at different rates. There are two main types: dry sarcoids and ulcerated (weepy and inflamed) sarcoids. They are generally benign and don't spread to internal organs, but they can cause serious problems if they obstruct bodily functions like urination or defecation.Conventional vs. Holistic ApproachesWith traditional veterinary treatments, which include cutting, freezing, or surgically removing sarcoids, recurrence is common. Holistic practitioners aim to understand why the sarcoids appeared in the first place. Removing growths will not solve the internal imbalance that allowed them to develop.Potential Causes and TriggersSarcoids, which may originate from the bovine papillomavirus, behave like viruses, flaring up with stress, toxicity, and nutritional deficiencies. Horses with compromised immune systems due to anxiety, malnutrition, or chronic stress are more prone to developing sarcoids. Events like moving farms, losing a herd mate, accidents, poor-quality hay, or vaccines can act as triggers.Chemical Toxicity and VaccinesSarcoids could result from exposure to chemicals. Sprays on hay, some feeds, and vaccines can attack horses' immune systems. When their immune system is under strain, dormant viruses can activate, allowing sarcoids to spread rapidly. Sarcoids often tend to appear soon after vaccinations, especially in compromised horses.Skin as an Elimination OrganThe skin acts as a pathway for the body to release toxins and reflect internal imbalances. When sarcoids appear on the skin, they are often signs of an internal issue.Malabsorption and Nutritional GapsA horse may seem to be getting good nutrition, yet still be malnourished if it does not absorb nutrients properly. Ulcers or chronic nervous system stress can interfere with their nutrient uptake and contribute to a weakened immune system.Environmental and Age FactorsAt around 15, horses often start showing signs of conditions that have been building silently for years. Chronic stress, aging, and accumulated exposure to harmful substances can contribute to immune dysfunction and tumor development.The Role of Detoxification and the LiverThe liver detoxifies chemicals, medications, and environmental toxins. If it is overburdened, the immune system suffers. Many horses show signs of liver strain if they have been on long-term medication or exposed to repeated vaccinations and chemical-laden feeds.Immune System and Pathogen LoadChronic issues like thrush, scratches, or recurrent parasite infections indicate a compromised immune system. Parasites, bacteria, viruses, mold, and fungi often coexist, increasing the toxic load and making it harder for horses to maintain internal balance.Using Nutritional TherapyNutritional therapy is a preferred holistic strategy. It involves using single nutrients in specific doses to clean up toxicity, correct imbalances, and support immune health. Antioxidants like selenium and vitamin C can help to detoxify chemicals and support liver function.Links and resources:Connect with Elisha Edwards on her
My guest is Dr. Melissa Ilardo, Ph.D., professor of biomedical informatics at the University of Utah. We discuss the interplay between genes and behaviors, including how certain behaviors can improve resilience by changing gene and organ function, as well as natural selection events happening in humans today. We also discuss the immune system–related reasons people find the smells of potential mates attractive—or not. We explore how physical and psychological traits are passed from one generation to the next, and the specific behaviors that can influence gene expression to improve health and performance. Melissa explains her lab's pioneering research on breath-hold training and how activation of the dive reflex through breath holding can significantly improve oxygen availability by changing spleen size and function. We also delve into the medical uses and ethics of gene editing to cure disease in both babies and adults. For those interested in genes and inheritance, human performance, immune system function, and natural selection, this episode illustrates the remarkable interplay between human nature and nurture. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman Eight Sleep: https://eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Melissa Ilardo 00:02:35 Nature vs Nurture, Gene Expression, Eye Color 00:07:06 Sponsors: Joovv & Eight Sleep 00:10:24 Epigenetics, Trauma, Mutations; Hybrid Vigor, Mate Attraction 00:15:47 Globalization; Homo Sapiens, Mating & Evolution; Mutations 00:25:28 Sea Nomads, Bajau & Moken Groups; Free Diving, Dangers & Gasp Reflex 00:32:52 Cultural Traditions, Free Diving & Families; Fishing 00:35:36 Mammalian Dive Reflex, Oxygen, Spleen, Cold Water & Face; Exercise 00:42:43 Sponsors: AG1 & LMNT 00:46:00 Free Diving, Spleen, Thyroid Hormone, Performance Enhancement 00:52:00 Dive Reflex, Immune System; Swimming & Health; Coastal Regions & Genetics 00:55:17 Female Free Divers, Haenyeo, Cold Water, Age, Protein 01:03:20 Human Evolution & Diet, Lactase, Fat 01:05:07 Korean Female Free Divers & Adaptations, Cardiovascular, Pregnancy 01:10:13 Miscarriages & Genetic Selection; Bajau, External Appearance, Mate Selection 01:17:15 Sponsor: Function 01:19:03 Free Diving, Underwater Vision; Super-Performers & Genetics 01:25:01 Cognitive Performance, Autism, Creativity; Genetic Determinism & Mindset 01:36:30 Genetics & Ethics, CRISPR, Embryo Genetic Screening 01:44:36 Admixture, Genetics; Are Humans a Single Species? 01:49:39 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
True health encompasses so much more than just diet and exercise. However, you don't need complicated routines, a lot of money, or elaborate gadgets to make a positive impact on your health. Some of the most powerful things you can do to improve your longevity, boost your immune system, and lower your stress have to do with simple behaviors and habits you can create in your home. Today, you're going to learn about the impactful role that community can have on your microbiome, your disease risk, and your overall health. On this episode of The Model Health Show, you're going to hear my conversation with the incredible Dr. Amy Shah for her podcast, Save Yourself. In this conversation, we discussed the importance of shared family meals, how to prioritize eating real food, and why your relationships are a key determinant of your health. This episode is packed with the science behind how cultivating healthy relationships can influence your microbiome, your sleep, your immune system, and so much more. You're also going to learn the top two most important things you can do to transform your health. I hope you enjoy my conversation with Dr. Amy Shah! In this episode you'll discover: The most important part about being human. (09:48) How eating with your family can impact your health. (12:22) Why being part of a community can improve your microbiome. (14:47) The health benefits of multi-generational living. (17:52) An interesting fact about humans, evolution, and menopause. (23:13) Why creating your own community can transform your life. (25:24) How sharing meals with your children can reduce their risk of obesity and disordered eating. (28:04) The connection between the time spent at a table and health outcomes. (33:45) What the #1 factor is that influences longevity is. (38:04) Which hormone is the antidote to stress. (39:27) Why personalization is the key to health. (41:22) The most powerful nutrition shift you can make. (41:44) How American children's diets have become inundated with ultra-processed food. (42:37) The #1 way to minimize the ultra-processed food in your diet. (45:50) What post-ingestive feedback is. (49:14) What sleep nutrients are. (54:41) How often you should aim to share a meal with others. (58:09) Items mentioned in this episode include: Beekeepersnaturals.com/model - Save 25% sitewide through May 27! PaleoValley.com/model - Use code MODEL for 15% off! Save Yourself with Dr. Amy Shah - Subscribe to Dr. Amy Shah's podcast! Eat Smarter Family Cookbook - Transform the health, fitness, and connection of your entire family with the Eat Smarter Family Cookbook! Be sure you are subscribed to this podcast to automatically receive your episodes: Apple Podcasts Spotify Soundcloud Pandora YouTube This episode of The Model Health Show is brought to you by Beekeeper's Naturals and Paleovalley. Reinvent your medicine cabinet for with clean, effective products powered by the beehive & backed by science. Shop the Memorial Day Sale now through May 27th and get 25% off sitewide at beekeepersnaturals.com/model. Use my code MODEL at PaleoValley.com/model to save 15% sitewide on nutrient dense snacks, superfood supplements, and more.
In a world where chronic illness is skyrocketing and people are spending thousands on supplements and labs with little relief, what if we've been focusing on the wrong thing? In this episode, Dr. Jannine Krause sits down with Mel Hopper Koppelman, Program Director at Synthesis Health Lab, to talk about a radically different — and incredibly effective — approach to healing. Instead of chasing symptoms or optimizing labs, Mel focuses on repairing the foundation of the nervous system and working with the first principles of health. The result? A 50%+ reduction in symptoms for many chronic illness sufferers without endless supplements or constant testing. Mel blends ancient healing wisdom with modern neuroscience and has helped thousands recover from chronic fatigue, autoimmunity, fibromyalgia, and more — especially those who felt like they had “tried everything.”
Story at-a-glance Cancer is affecting younger individuals more than before. There's even a case wherein a 13-year-old has developed metastatic pancreatic cancer Inflammation plays a central role in cancer development, with poor diet, environmental chemicals, and persistent viral infections contributing to immune system suppression The COVID-19 jab contributes to cancer risk through persistent inflammation from spike proteins Your immune system, particularly T-cells and natural killer cells, is crucial for fighting cancer Practical preventative measures include eating whole foods instead of processed foods, reducing chemical exposure, maintaining proper sleep, and avoiding mRNA shots
Send us a textEpisode Summary: Dr. Michael Wheeler talks about neuroimmune interactions, exploring how the immune system and brain communicate, particularly through the blood-brain barrier and meninges; how chronic stress and inflammation can alter brain circuits, contributing to mood disorders like depression; how drugs like psilocybin and MDMA may reduce inflammation by modulating immune cells in the meninges, offering potential therapeutic benefits.About the guest: Michael Wheeler, PhD is an Assistant Professor of Neurology at Harvard Medical School. His lab studies how immune responses influence behavior, mood disorders, and addiction.Key Conversation Points:The blood-brain barrier (BBB) is not as impermeable as once thought, allowing immune signals like cytokines to influence brain function even in healthy states.Chronic stress can weaken the BBB, increasing inflammation and affecting mood-regulating circuits, potentially contributing to depression.Microglia, the brain's resident immune cells, help maintain neural circuits by pruning synapses and regulating metabolism.Psychedelics like psilocybin and MDMA can reduce inflammation by prompting immune cells (monocytes) to leave the meninges, potentially via vascular effects.These psychedelics may act in a context-specific “window,” requiring a dysregulated tissue state to exert anti-inflammatory effects, not as broad-spectrum anti-inflammatories.Neuroinflammation may underlie some treatment-resistant depression cases, suggesting immunotherapy could complement traditional psychiatric treatments.The brain encodes peripheral immune signals, like gut inflammation, in specific circuits, which can “remember” and recreate inflammatory responses.Aging may naturally increase blood-brain barrier leakiness, heightening the brain's susceptibility to peripheral inflammation.Future research aims to explore how psychedelics influence plasticity and their potential in treating inflammation-related diseases beyond psychiatry.Related episode:M&M 2: Psilocybin, LSD, Ketamine, Inflammation & Novel Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off For all the ways you can support my efforts
Gut Health for Women: Why Fatigue, Bloating, and Mood Swings Might Start in Your Gut Are you feeling fatigued, moody, bloated—or just not quite yourself lately? You're not alone. And it might be your gut trying to get your attention. In this episode of The Natalie Tysdal Podcast, I open up about a deeply personal health crisis that became a turning point in my wellness journey (don't judge me for crying!). As a health journalist with over 30 years of experience interviewing doctors and wellness experts, I've learned that gut health plays a much bigger role in our energy, hormones, immunity, and mood than most of us realize—especially as women. What You'll Learn in This Episode: The four essential things every woman needs to know about gut health How hidden gut issues can show up as fatigue, anxiety, poor sleep, hormone imbalance, and more Early warning signs your gut is out of balance—and what to do before it becomes a crisis My step-by-step strategies for gut healing, including nutrition, supplements, and lifestyle shifts One simple thing you can do this week to start resetting your gut health
Vitamin D is more than a vitamin—it's a hormone that influences everything from your immune system to cardiovascular health, cognition, and longevity. In this conversation, Dr. Michael Holick breaks down the science of vitamin D synthesis, the truth about sun exposure vs. supplements, and why vitamin D deficiency is far more common—and more dangerous—than most people realize. You'll learn how skin pigmentation, UVB exposure, and supplementation protocols impact your vitamin D levels, and why D3 is more effective than D2. Dr. Holick also dives into mood, cognition, and the controversial role of vitamin D in chronic disease and COVID outcomes. With dosage guidelines by age and weight, plus practical advice on avoiding vitamin D toxicity, this episode is a masterclass on one of the most important—yet misunderstood—nutrients in health and longevity. Learn more about Dr. Michael F. Holick: https://drmichaelholick.org/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/
In this episode of the Ancient Health Podcast, Dr. Motley explores the intricate relationship between PTSD and the immune system. He discusses the historical context of PTSD, its neurological impacts, and the emotional and physical interconnections that arise from trauma. Dr. Motley emphasizes the importance of ancient healing techniques and modern therapeutic approaches, providing listeners with practical strategies for releasing trauma and improving overall health. He encourages those suffering from PTSD to seek help and offers resources for healing. Takeaways PTSD can severely affect both mental and physical health. The body develops defense mechanisms in response to trauma. Historical perspectives on PTSD show it has existed for centuries. Ancient healing techniques can provide valuable insights for modern therapy. Techniques like NET and EMDR can help release trauma. PTSD can affect the immune system tremendously. ------ Show notes: NETmindbody.com Autonomic Homeostasis Activation - autonomichealing.com Feelings Buried Alive Never Die by Karol Kuhn Truman ------ Follow Doctor Motley Instagram Twitter/x Facebook Website ------ *Do you have a ton more in-depth questions for Doctor Motley? Are you a health coach looking for more valuable resources and wisdom? Join his membership for courses full of his expertise and clinical wisdom, including a course on the relationship between the physical and emotional body, plus bring all your questions to his frequent live Q+A's! Join here
This episode is brought to you by WHOOP, Pique and Blokes & Joi. What if the key to improved health - TRUE VITALITY & LONGEVITY - lies not just in medicine but in your environment? Join us as we unlock the secrets of detoxification and integrative medicine with Dr. Aly Cohen, MD, a leading integrative rheumatologist and environmental health specialist. This episode promises to transform your understanding of wellness by blending traditional Western practices with holistic approaches, like acupuncture, to enhance disease management and prevention. Dr. Cohen shares her journey from a conventional medical background to a more comprehensive approach that incorporates environmental medicine, providing a fresh perspective on health. "Understanding the broader implications of environmental health, like microplastics and endocrine-disrupting chemicals, empowers us to make informed choices for a more resilient life." - Aly Cohen, MD Follow Aly @thesmarthuman Follow Chase @chase_chewning ---- In this episode we discuss... (00:00) Aly's Intro to Detoxify Your Body and Home (12:48) Which Detoxifying Foods to Prioritize (21:23) Activated Charcoal and Detoxification (26:05) Which Detoxification Practices Are Optimal (40:42) Understanding Toxins and Major Health Risks (48:29) Common Toxins in Everyday Products (55:00) Microplastics and Health Risks (01:03:05) How to Eliminate Plastics (01:07:09) Effective Detoxifying Household Changes (01:20:41) Water Quality and Effective Filtration Solutions (01:32:41) Optimizing Natural Body Detoxification Pathways (01:41:37) Embarking on a Detoxification Journey ----- Episode resources: Get your WHOOP band and first month FREE at https://join.whoop.com/everforward 20% off for life the best match and tea at http://piquelife.com/everforward 10% off any diagnostic labs with code CHASE at https://www.JoiAndBlokes.com/chase Watch and subscribe on YouTube Get her book Detoxify Learn more at AlyCohenMD.com
Story at-a-glance New research shows inflammation directly influences mood and behavior by sending chemical signals that activate anxiety circuits in the brain, helping to explain emotional aftereffects of illness Specific inflammatory cytokines stimulate neurons in brain regions responsible for processing fear, while anti-inflammatory signals calm these same neural pathways Scientists discovered that certain immune molecules function like neurotransmitters in the brain, influencing social behavior and emotional states independently of inflammation Blocking inflammation incorrectly backfires; it triggers more intense anxiety as the body produces additional inflammatory messengers that overstimulate fear circuitry Managing inflammation-related mood issues requires reducing linoleic acid (LA) intake from vegetable oils, supporting mitochondrial function, getting safe sun exposure, avoiding alcohol and monitoring emotional symptoms after illness