A biological system that protects an organism against disease
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Join us for our Histamine and Hormones Training on September 28th!Why do some women feel amazing during certain phases of their cycle while others feel absolutely wrecked?In this episode, I'm joined by Michelle Shapiro, RD, a functional dietitian who works with clients navigating Mast Cell Activation Syndrome (MCAS) and histamine issues. She also lives with MCAS herself, bringing both professional insight and personal experience to the table.Why do histamine flares hit hardest right when hormones shift? Tune in as we break down the menstrual cycle, step by step, and look at how mast cells and histamines interact with rising and falling hormones. The patterns aren't always what you'd expect, and tracking them can change everything about how you handle symptoms.You'll Learn:The role of mast cells in the immune system and why histamine release can trigger so many symptomsThe link between rising estrogen and increased histamine releaseWhy people with histamine issues can have paradoxical hormone symptomsHow long histamines actually stay in your system, and ways to avoid long-term sufferingWhat happens when conditions like POTS and hypermobility overlap with histamine issues during the cyclePractical strategies for tracking cycle patterns to spot histamine-driven flaresThe debate around antihistamines, pregnancy, and de-stigmatizing medication for symptom reliefWhy lowering histamines must come before deeper root-cause work like gut or mineral protocolsThe connection between histamines, mast cells, and endometriosisTimestamps:[00:00] Introduction[10:17] How estrogen and histamine interact to trigger symptoms during the menstrual cycle[13:53] How progesterone and luteal phase shifts trigger unexpected symptoms in histamine, POTS, and hypermobility clients[21:47] Tracking cycles and temperatures to spot patterns and histamine flares[25:53] Using antihistamines and other strategies to manage flares and reduce stigma around medication[48:09] Understanding the immune system's role in endometriosis and its connection to histamine and progesteroneListen to Other Hormone Healing Episodes with Michelle:MCAS, POTS, & Hypermobility Part 1 | Listen HereMCAS, POTS, & Hypermobility Part 2 | Listen HereThe Root Cause of Reflux | Listen HereResources Mentioned:Ovia Cycle-tracking App | WebsiteNatural Cycles Fertility Awareness App | WebsiteOura Ring | WebsiteTempdrop Wearable Sensor | WebsiteRead Your Body App | WebsitePodcast with Nina Boyce on Fertility Awareness Method | PodcastFind more from Michelle:Michelle Shapiro RD | InstagramMichelle Shapiro RD | WebsiteMichelle Shapiro Nutrition | YouTubeFind more from Amanda:Hormone Healing RD | InstagramHormone Healing RD | WebsiteHormone Healing RD | FacebookHormone Healing RD | YouTubeHormone Healing RD | TikTok
Dr. Derya Unutmaz joins Dr. Buck Joffrey to discuss the critical role of T cells in the immune system, their changes with aging, and the implications for chronic diseases. He emphasizes the importance of thymus regeneration and the microbiome's influence on health. The discussion also covers advancements in engineering immune cells for cancer treatment and the potential of AI in revolutionizing aging research and drug discovery. Unutmaz expresses optimism about the future of aging research, highlighting the need for a shift in how aging is perceived in the medical community. Learn more about Dr. Derya Unutmaz: https://www.jax.org/research-and-faculty/faculty/derya-unutmaz - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/
Nutritionist Leyla Muedin discusses the importance of trace minerals selenium and iodine, their health benefits, and food sources. Leyla details the roles of selenium in immunity, thyroid function, antioxidant protection, reproductive health, DNA synthesis, and reducing cancer risk. She addresses sources such as Brazil nuts, seafood, and enriched foods while cautioning about possible toxicity. Leyla then covers iodine's critical function in thyroid hormone production, brain development, and immune support, highlighting sources like seaweed and iodized salt. Emphasizing the global concern of iodine deficiency, especially in pregnant women, she underscores the minerals' significance for overall health.
Allergist Tina Sindher acknowledges that allergies may be affecting more people worldwide, influenced by a combination of factors such as environmental changes, modern lifestyles, urbanization, and evolving dietary habits. Prevention is playing catch-up, and promising new strategies include earlier food introduction than was popular only a few years ago. On the treatment front, hopes are rising for immunotherapies and a new prescription medicine, omalizumab, that addresses multiple allergens at once. While no single approach helps all, these strategies could allow millions worldwide to better manage their allergies, Sindher tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast. Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Sayantani (Tina) SindherConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Tina Sindher, a professor of medicine and allergy at Stanford University.(00:03:16) Inside the Immune ResponseWhy our immune systems trigger allergic reactions.(00:04:57) Genes vs. EnvironmentWhether genetics or environment drive allergy risks.(00:08:05) The Microbiome FactorThe role of the microbiome and early exposures in prevention.(00:09:17) A Global Allergy SurgeHow global allergy trends reveal rising health challenges.(00:11:56) Potent Food TriggersWhy some foods cause stronger and faster reactions.(00:13:49) Emerging RisksWhether Alpha-Gal signals new emerging allergy risks.(00:15:47) Multi-Food AllergiesHow multi-food allergies complicate diagnosis and treatment.(00:19:02) Preventing Allergies EarlyWhy early food introduction may help prevent allergies.(00:20:54) Skin's Role in AllergiesThe importance of infant skin health in allergy development.(00:23:39) Testing LimitationsThe limits of current testing methods to truly diagnose allergies.(00:25:13) Standard Testing ProcedureThe current methodologies deployed when testing for allergies.(00:27:28) New TherapiesHow new therapies like OIT and Xolair are reshaping treatment.(00:31:50) The Future of AllergiesThe potential of combined therapies to aid in allergy treatment.(00:34:33) Managing Seasonal AllergiesHow to manage seasonal allergies effectively at home.(00:37:08) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook
Many supplements claim to “boost” your immune system. Now, we all want to avoid getting sick during the winter months, but do any of these products really work? And is trying to “boost” your immune system even a good idea? Jonathan speaks with Professor Daniel M. Davis, MBE — a leading expert on immunology and Head of Life Sciences at Imperial College London. Daniel has published 145 scientific papers, authored four best-selling science books, and spent 25 years researching how our immune system works. He even helped discover the immune synapse, a breakthrough that changed our understanding of immunity. Daniel explains how your immune system really works, why it's connected to mental health, and how it can even detect cancer cells. He also clears up common myths and shares what genuinely helps keep your immune system strong through the winter months — and what won't make a difference. By the end of the episode, you'll know the practical, science-backed steps you can take to reduce your risk of colds and flu this winter without wasting money on products that don't deliver. Unwrap the truth about your food
Dr. Hoffman continues his conversation with Dr. Martin Picard, Chair in Energy and Health, and Professor of Behavioral Medicine at Columbia University, as well as head of the Mitochondrial PsychoBiology Lab.
Dr. Martin Picard, Chair in Energy and Health, and Professor of Behavioral Medicine at Columbia University, as well as head of the Mitochondrial PsychoBiology Lab, delves into the complex functions of mitochondria beyond their well-known role as cellular powerhouses. Dr. Picard shares his journey from biology to psychobiology, exploring the intersection between mitochondrial function, mental health, and overall well-being. He discusses how mitochondria not only produce energy but also influence behaviors, stress responses, and healing processes. The conversation highlights recent findings on mitochondrial roles in psychiatric disorders, the impact of diet and lifestyle on mitochondrial health, and the potential of ketogenic diets in treating psychiatric conditions. Dr. Picard also previews his upcoming book on understanding life and health from an energetic perspective. The episode emphasizes a holistic approach to health, integrating mind-body practices and lifestyle changes to support mitochondrial function.
This Week in Machine Learning & Artificial Intelligence (AI) Podcast
Today, we're joined by Animesh Koratana, founder and CEO of PlayerZero to discuss his team's approach to making agentic and AI-assisted coding tools production-ready at scale. Animesh explains how rapid advances in AI-assisted coding have created an “asymmetry” where the speed of code output outpaces the maturity of processes for maintenance and support. We explore PlayerZero's debugging and code verification platform, which uses code simulations to build a "memory bank" of past bugs and leverages an ensemble of LLMs and agents to proactively simulate and verify changes, predicting potential failures. Animesh also unpacks the underlying technology, including a semantic graph that analyzes code bases, ticketing systems, and telemetry to trace and reason through complex systems, test hypotheses, and apply reinforcement learning techniques to create an “immune system” for software. Finally, Animesh shares his perspective on the future of the software development lifecycle (SDLC), rethinking organizational workflows, and ensuring security as AI-driven tools continue to mature. The complete show notes for this episode can be found at https://twimlai.com/go/746.
PODCAST: On today’s Action Line with host Scott Walker, we’re joined by Dr. Michael Derrick from Murfreesboro Medical Clinic’s Westlawn Office. Dr. Derrick s
My guest is Michael Snyder, PhD, professor of genetics at Stanford and an expert in understanding why people respond differently to various foods, supplements, behavioral and prescription interventions. We discuss how to optimize your health and lifespan according to what type of glucose responder you are, which genes you express, your lifestyle and other factors. Dr. Snyder also explains the key ages when you need to be particularly mindful about following certain health practices. We also discuss how people respond in opposite ways to different fiber types. This episode ought to be of interest and use to anyone seeking to understand their unique biological needs and how to go about meeting those needs. Sponsors AGZ by AG1: https://drinkag1.com/huberman Wealthfront*: https://wealthfront.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman *This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27, 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps 00:00 Michael Snyder 03:33 Healthy Glucose Range, Continuous Glucose Monitors CGM, Hemoglobin A1c 09:02 Individual Variability & Food Choice, Glucose Spikes & Sleepiness 12:18 Sponsors: AGZ by AG1 & Wealthfront 15:16 Glucose Spikes, Tools: Post-Meal Brisk Walk; Soleus “Push-Ups”; Exercise Snacks 21:06 Glucose Dysregulation, Diabetes & Sub-Phenotypes, Tool: Larger Morning Meal 28:34 Exercise Timing, Muscle Insulin Resistance 30:49 Diabetes Subtyping, Weight, Glucose Control; Incretins 35:41 GLP-1 Agonists, Diabetes, Tool: Muscle Maintenance & Resistance Training 38:40 Metformin, Berberine, Headaches 41:01 GLP-1 Agonists, Cognition, Longevity, Tool: Habits Support Medication; Cycling 47:41 Subcutaneous vs Visceral Fat, Organ Stress 49:10 Sponsors: David & Eight Sleep 51:58 Meal Timing & Sleep, Tools: Post-Dinner Walk, Routines, Bedtime Consistency 57:16 Microbiome, Immune System & Gut; Diet & Individual Variability 1:02:52 Fiber Types, Cholesterol & Glucose, Polyphenols 1:09:50 Food As Medicine; Fiber, Microbiome & Individual Variability; Probiotics 1:18:48 Sponsor: Function 1:20:35 Profiling Healthy Individuals, Genomes, Wearables 1:26:31 Whole-Body MRIs, Nodules, Healthy Baseline, Early Diagnosis 1:34:07 Sensors, CGM, Sleep, Heart Rate Variability HRV, Tools: Mindset Effects, Increase REM 1:39:30 HRV, Sleep, Exercise, Tool: Long Exhales; Next-Day Excitement & Sleep 1:42:48 Organ Aging, “Ageotypes”; Biological Age vs Chronological Age 1:49:41 Longevity, Health Span, Genetics, Blue Zones 1:52:19 Epigenetics, Viral Infection & Disease 1:58:54 ALS, Heritability; Neuroprotection, Nicotine 2:03:47 Air Quality, Allergies, DEET & Pesticides, Inflammation, Mold; Microplastics 2:15:02 Single-Drop Blood Test & Biomarkers, Wearables, Observational Trials 2:20:33 Acupuncture, Blood Pressure 2:26:40 Immersive Events & Mental Health Benefits 2:34:59 Data, Nutrition & Lifestyle; Siloed Health Care vs Personalized Medicine 2:43:06 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Social Media, Neural Network Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
Ireland has one of the lowest breastfeeding rates among high-income countries, influenced by social, cultural, and systemic factors. Around 60% breast feed early on but this drops to around 40% within 3 months and plummets to less than 10% at 6 months. How breast feeding provides significant benefits to the baby's immune system. All to discuss with Professor Luke O Neill , Professor of Biochemistry at the school of Immunology, Trinity College.
View the Show Notes For This Episode Dr. Marc Ryan discusses Hashimoto's Thyroiditis with Dr. Ben Weitz. [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.] Podcast Highlights In this episode of the Rational Wellness Podcast, Dr. Ben Weitz hosts Dr. Mark Ryan, a licensed acupuncturist, herbalist, and functional medicine practitioner, to discuss Hashimoto's Thyroiditis, the most common autoimmune condition in the US. Dr. Ryan shares his personal journey with Hashimoto's and his path towards specializing in its treatment. They delve into the causes, symptoms, and the complexities of managing this condition, emphasizing the importance of a holistic approach. They also discuss the nuances of various thyroid medications, the impact of diet, and the role of supplements. The episode provides insights into functional and traditional Chinese medicine approaches to treating Hashimoto's, stressing the need for comprehensive testing and individualized care. 00:30 Meet Dr. Mark Ryan: Expert on Hashimoto's Thyroiditis 00:59 Understanding Hashimoto's Thyroiditis 02:52 Dr. Ryan's Personal Journey with Hashimoto's 05:45 Common Symptoms of Hashimoto's 07:11 Conventional vs. Functional Medicine Approaches 07:46 The Role of Thyroid Hormones 12:59 Autoimmunity and the Immune System 16:33 Comprehensive Testing for Hashimoto's 20:13 Addressing Adrenal Dysfunction 21:28 Managing Blood Sugar Levels 24:14 Product Break: Apollo Wearable 25:45 Hypothyroidism and Its Effects on the Body 25:56 Understanding Hypothyroidism and Kidney Function 28:23 The Impact of Testosterone on Kidney Health 30:16 Thyroid Hormone and Heart Disease Risk 31:41 Nutritional Supplementation for Hashimoto's 31:47 The Controversy of Iodine in Thyroid Health 37:30 Balancing Thyroid Medication 38:52 Dietary Recommendations for Hashimoto's Patients 43:51 Final Thoughts and Contact Information _______________________________________________________ Dr. Marc Ryan is a licensed acupuncturist, herbalist, and functional medicine practitioner. He's written two books about Hashimoto's thyroiditis, how to Heal Hashimoto's and The Hashimoto's Healing Diet. He teaches at YoSan Acupuncture College, and his practice is devoted to treating patients with Hashimoto's. His website is HashimotosHealing.com Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.
Send us a textCellular clean up by immune cells and how early-life fructose exposure leads to neurodevelopmental problems.Episode Summary: Dr. Justin Perry talks about the body's constant cellular turnover—about 3 million cells die per second in adults (double in children and women)—handled by phagocytes like macrophages that engulf and digest debris to prevent diseases like lupus. They explore phagocytosis steps, macrophage adaptations in tissues like the brain (microglia), and how high fructose intake impairs microglial function in developing mice, leading to uncleared brain cells and anxiety-like behaviors, with implications for human neurodevelopmental disorders amid rising fructose consumption.About the guest: Justin Perry, PhD is an immunologist and clinical psychologist who leads a lab at Memorial Sloan Kettering Cancer Center focusing on how the body clears dead cells and debris to maintain homeostasis.Discussion Points:The body turns over 1-2% of its 30 trillion cells daily, mostly blood cells, but neurons in kids and endometrium in women turnover at ~2x this ratePhagocytosis involves "find me," "eat me," and digestion signals; failures can cause autoimmunity.Microglia are brain macrophages that uptake fructose via GLUT5 transporter.Early high fructose exposure (comparable to one soda daily) impairs the pruning of synapses and dead neurons.In mice, prenatal or postnatal fructose causes phagocytosis deficits in the prefrontal cortex, leading to heightened fear responses and poor fear extinction, mimicking anxiety disorders.Fructose correlates with rising neurodevelopmental issues like autism and anxiety; it's passed via breast milk, and liquid forms (e.g., sodas) overwhelm metabolic shields more than solid fruits.Macrophages may hold keys to diseases from atherosclerosis to cancer; deleting GLUT5 in microglia reverses fructose's effects, hinting at evolutionary roles in aging or low-oxygen states.Related content:M&M 215: Cancer Metabolism: Sugar, Fructose, Lipids & Fasting | Gary PattiArticle | Dietary Fructose & Metabolic Health: An Evolutionary PerspectiveReference Paper:Study | Early life high fructose impairs microglial phagocytosis and neurodevelopment*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts
Discover the powerful connection between the health of our soil and our own well-being as Merry and Cathy sit down with Louis De Jaeger, a visionary soil preservationist and environmental designer. Inspired by his grandmothers, Louis has dedicated his life to regenerative agriculture and designing systems that heal the planet. From how our food choices impact our health to the critical role trees play in fighting climate change, this conversation will inspire you to see the ground beneath your feet in a whole new way. Thank you and have a terrific holiday!Louis De Jaeger's Bio:Louis De Jaeger is a visionary on a mission to impact our world profoundly. Three primary objectives guide his life's purpose: regenerate, inspire, and celebrate. He endeavors to rejuvenate vast expanses of land, ignite inspiration in countless individuals, and infuse every endeavor with a joyful spirit and gratefulness. He firmly believes that transitions should be as enjoyable as they are meaningful. A prolific author, Louis has penned two enlightening books that explore the future of agriculture & food and the wonders of food forests. He is a driving force behind various impactful campaigns, exemplifying his commitment to creating positive change. He founded and is CEO of Commensalist, a distinguished landscape architecture firm. Through Commensalist, Louis and his team embark on awe-inspiring journeys, transforming ambitious projects spanning an impressive 1.500 hectares across diverse global locations. Beyond the written word and architectural innovations, Louis is an award-winning filmmaker dedicated to raising awareness about sustainability and our planet's future. His latest documentary, "Eat More Trees," introduces the world to the enchanting realm of the food tree. Louis De Jaeger is resolute and unwavering in all his endeavors. He is driven by a passion for advocating for sustainability and bringing its magic to life. Through his diverse talents and indomitable spirit, he invites us all to join him on this extraordinary journey of regeneration, inspiration, and pure enjoyment as an international keynote speaker. Connect with Louis:Book: SOS: Save Our Soils - https://www.amazon.com/SOS-regenerative-farming-health-planet/dp/B0FF3R1NKKWebsite: www.louisdj.comYouTube: https://www.youtube.com/@commensalistfutureprooflan1860 Facebook: https://www.facebook.com/foodforestinstituteInstagram: https://www.instagram.com/louis.de.jaegerTikTok: https://www.tiktok.com/@louis.dejaeger X: https://x.com/LouCommensalistLinkedIn: https://www.linkedin.com/in/louisdejaeger/ Threads: https://www.threads.com/@louis.de.jaegerThank you for listening. Please check out @lateboomers on Instagram and our website lateboomers.us. If you enjoyed this podcast and would like to watch it or listen to more of our episodes, you will find Late Boomers on your favorite podcast platform and on our new YouTube Late Boomers Podcast Channel. We hope we have inspired you and we look forward to your becoming a member of our Late Boomers family of subscribers.
In this episode, we welcome Professor Mervyn Singer, author of Sepsis 3.0. Sepsis remains one of the most complex and deadly conditions in critical care. In this conversation,Professor Singer shares his perspectives on the shifting landscape of sepsis treatment, the role of antibiotics, steroids, metabolic interventions, and the future ofprecision medicine. He also challenges some long-standing dogmas and emphasizes the importance of individualized care over rigid guidelines.Key Topics and Chapters:The Evolution of Sepsis ManagementHistorical perspectives on sepsis treatmentEarlier recognition and intervention leading to improved outcomesCurrent Challenges and Research DirectionsOrgan dysfunction and recovery in sepsisThe importance of metabolic manipulation and mitochondrial functionThe Role of the Immune System in SepsisUnderstanding hyper- and hypo-inflammatory responsesSteroid use in critical illness—when it works and when it doesn'tAntibiotics in Sepsis: How Soon, How Long, and How Much?The changing approach to antibiotic timing and durationThe impact of microbiome disruption and antibiotic toxicityRethinking the one-hour antibiotic ruleLessons from COVID-19 and Their Impact on Sepsis ResearchThe importance of phenotype-driven treatmentsMissed opportunities in clinical trials and biobankingThe Beta-Blocker Debate in SepsisPotential benefits in selected patientsThe challenge of distinguishing compensatory tachycardia from harmful sympathetic overdriveRethinking Fever ManagementIs fever protective or harmful?When to treat and when to leave it aloneGuidelines vs. Individualized CareThe balance between evidence-based medicine and clinical expertiseThe dangers of rigid mandates and protocolsThis engaging discussion provides a fresh perspective on the current state and future of sepsis management, emphasizing the need for precision medicine, nuanced clinical decision-making, and ongoing research.References:Im Y, Kang D, Ko RE, et al. Time-to-antibiotics and clinical outcomes in patients with sepsis and septic shock: a prospective nationwide multicenter cohort study. Crit Care. 2022;26(1):19. Published 2022 Jan 13. doi:10.1186/s13054-021-03883-0 HereSakkat A, Alquraini M, Aljazeeri J, Farooqi MAM, Alshamsi F, Alhazzani W. Temperature control in critically ill patients with fever: A meta-analysis of randomized controlled trials. J Crit Care. 2021;61:89-95. doi:10.1016/j.jcrc.2020.10.016 HereHasegawa D, Sato R, Prasitlumkum N, et al. Effect of Ultrashort-Acting β-Blockers on Mortality in Patients With Sepsis With Persistent Tachycardia Despite Initial Resuscitation: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Chest. 2021;159(6):2289-2300. doi:10.1016/j.chest.2021.01.009 Here
Can years teaching in a classroom make you less likely to get sick? Dr. Sanjay Gupta answers a listener's question about immunity and shares smart strategies for supporting your immune system as cold and flu season kicks off. Plus, how you can get better sleep – and more of it – this fall. Our show is produced by Eryn Mathewson, Jennifer Lai, Grace Walker, Lori Galaretta, Jesse Remedios, Sofia Sanchez, Kyra Dahring, and Madeleine Thompson. Medical Writer: Andrea Kane Showrunner: Amanda Sealy Senior Producer: Dan Bloom Technical Director: Dan Dzula Learn more about your ad choices. Visit podcastchoices.com/adchoices
Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz or www.curranz.co.uk to order yours This week on the podcast Mikki speaks to naturopath Erin O'Hara about a resilient immune system. Erin chats about her early years as a professional athlete before switching gears and diving into natural health and naturopathy. Mikki and Erin chat about signs of a robust versus struggling immune system, whether there is such a thing as ‘boosting' your immune system and what foundational lifestyle and supplements exist to support immunity.https://www.erinohara.co.nz/Erin O'Hara combines her knowledge of Naturopathy and Science to provide an integrative and evidence-based approach to wellbeing. She has been involved in the Health and Wellbeing Industry for about 20 years through extensive University study (BSc and BNatMed), scientific research, and an intrinsic passion for health & wellbeing. Her functional medicine approach addresses the underlying causes of disease through extensive testing and looking at the interactions among genetic, environmental, and lifestyle factors that can influence your health and cause disease. She utilises the best Evidence-Based Complementary Therapies to work in conjunction with conventional treatments. Drawing from her clinical experience and knowledge she takes quality time with each patient to understand the root cause of the disease, analysing test results, and provides an integrative approach to wellbeing.Erin works with general naturopathy patients and is very experienced in complex hormonal issues, integrative oncology support, autoimmune conditions, digestive disorders, and mental health. There is no "one size fits all" wellness plan so her consultations are tailored to your individual and unique needs. Erin sees a wide range of patients, from children to elderly, who are seeking to improve their health, heal naturally, or support for an underlying health condition. Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwilliden
I'm obsessed with this conversation. Hali Laricey taught me how to read my CBC with differential like a detective - and you probably already have years of these sitting in your patient portal right now. Those "normal" labs everyone dismisses? They're actually hiding specific patterns that can predict autoimmune flares months before symptoms hit. Hali breaks down the exact functional ranges for neutrophils, lymphocytes, and monocytes that reveal bacterial loads, viral activity, and chronic infections like EBV. This isn't about ordering expensive specialty tests - the CBC with differential is available anywhere and costs almost nothing. If you've been told your labs are normal but you still feel terrible, this episode will give you the tools to have empowered conversations with your healthcare team.For the full show notes, links and transcript visit inspiredliving.show/207
What if your immune system was shaping your personality without you even knowing? In this clip, immunologist Dan Nicolau reveals surprising science behind the mind-body connection, how curiosity and forgiveness affect health, and why infections like toxoplasmosis can radically change behavior.Dan NicolauListen to the full episode here.Watch the full episode on YouTube here.***This episode is sponsored by Spatone – the No.1 iron-rich water supplement.This is a product I genuinely believe in — one I've used personally and recommended in the clinic for years. Spatone is a natural iron-rich water that's incredibly gentle on the stomach. No harsh tablets, no digestive upset — just one naturally sourced ingredient that works.If you're looking for iron support that actually feels good to take, this is the one I trust. You can pick up Spatone at Boots: Spatone Apple Daily Iron Shots + Vitamin C 28 Sachets - Boots**This episode is also sponsored by London Nootropics, the best-in-class adaptogenic coffee I trust. Made with Hifas da Terra mushroom extracts, it supports focus, calm, and energy, and helps you stay sharp throughout the day. Enjoy 20% off with code LIVEWELLBEWELL at londonnootropics.com***If you enjoyed this episode you might also like:The Brain Immune Expert: ALERT! Social Media Is Reprogramming Your Immune System | Prof Nicolauhttps://youtu.be/2zNw6pzv8qk***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. https://sarahmacklin.substack.com/***Let's be friends!
Send us a textThe potential link between acetaminophen (Tylenol) and autism, with a surprise phone call from RFK partway through.Episode Summary: Dr. William Parker talks about autism spectrum disorder (ASD), its rising prevalence since the 1980s, and the controversial hypothesis that acetaminophen exposure in susceptible infants and children triggers most cases via oxidative stress. They discuss ASD's clinical definition; historical misconceptions like the "refrigerator mother" theory; genetic susceptibilities; acetaminophen's metabolism, which produces toxic byproducts in underdeveloped livers, leading to brain effects.About the guest: William Parker, PhD spent nearly 30 years as a professor at Duke University researching underlying causes of chronic conditions, including discovering the immune function of the human appendix and pioneering studies on immune systems in wild animals.Discussion Points:Autism is a spectrum disorder with core symptoms like social deficits, repetitive behaviors, and aversion to new stimuli.Parker argues overwhelming evidence points to acetaminophen as the primary trigger in susceptible individuals, causing oxidative stress via toxic metabolite NAPQI.Acetaminophen, marketed as Tylenol or paracetamol, was not tested for neurodevelopmental effects in neonatal animals until 2014, despite widespread use since 1886; it's metabolized differently in babies, whose livers lack mature detox pathways.Susceptibility factors include low glutathione (an antioxidant), poor sulfation/glucuronidation metabolism, folate receptor autoantibodies, and events like immune reactions that prompt acetaminophen use during oxidative stress.Regressive autism, where children lose milestones after seeming normal, often follows acetaminophen given for fevers or illnesses, explaining parental vaccine suspicions (as shots coincide with drug use).Adult acetaminophen is generally safe but causes liver toxicity in overdoses or with alcohol; antidote is NAC to boost glutathione.Parker has suggested to policymakers that we should avoid acetaminophen during pregnancy, birth, and early childhood (under age 3-5); parents should plan ahead for fevers/pain without it, but seek medical help for unusual symptoms.*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts
Episode 115 QUANTUM HEALING MEDITATION 1: WATER AND FLOW - Strengthening the Immune System Quantum Healing Meditations combine practical science with intangible spirituality. It creates physical change in the body through intention and visualization. Through creative and spontaneous visualization, the practice is said to strengthen the immune system and heal the body. This meditation is best done lying down (grab a blanket and get comfy). If you have headphones, please use them to block out any noise around you. Quantum Healing meditations are not passive, they are active meditations. You will be visualizing and aware of the intentions and vibrations of your body during this time. Please do not practice while driving. :) We are scheduling now for Season Two. If you are interested in receiving a reading with a loved one in the afterlife, or a soul existence reading as part of a future episode, contact linkingpodcast@gmail.com. Purchase Donna's books on Amazon. You can find out more about Donna here: https://linktr.ee/donnaboylemedium To schedule a private or group reading, contact Donna at dboylemedium@gmail.com Producer and editor: Donna Boyle Music from Freesound.org Opening: CD_PLENITUDE_002 kevp888 Closing: Pinecone ambient evanjones4 #theafterlife #mediumship #spirituality #soulpurpose #consciousness #channeling #evp #spirit #oneness #life #meditation #quantumhealing
Dr. Jim Keany, Chief Medical Officer at Dignity Health St. Mary Medical Center in Long Beach, joins The Bill Handel Show for 'Medical News'! Dr. Keany talks with Bill about a new form of immunotherapy that switches on your immune system to kill cancer cells, COVID rising in California, AI making humans dumb, and a flesh-eating bacteria that is killing people.
After more than 50 episodes, it's time to step back and share the biggest health lessons Dr. Odell has covered so far. In this episode, he brings together some of the most powerful nutrition and lifestyle strategies—practical steps you can start using right away. He'll talk about why fiber is your gut's best friend, how antioxidants and potassium protect your cells and brain, and why omega-3 fatty acids are essential at every stage of life. You will also hear how probiotics, healthy habits, detox practices, breathing techniques, natural light, and vagus nerve stimulation can completely change the way you feel. Along the way, Dr. Odell will briefly remind us of the dangers of excess sugar, processed seed oils, and even synthetic folic acid—plus what you should focus on instead. Whether you are new to the podcast or have been listening from the start, this episode is packed with takeaways that can truly elevate your health.
Ina Stelzer, Ph.D., explores how the maternal immune system adapts to support a healthy pregnancy and how disruptions can lead to complications like preterm birth. Her lab identifies early immune changes linked to spontaneous preterm birth and investigates the role of the maternal brain in regulating immune responses. Stelzer uses advanced technologies like mass cytometry and spatial proteomics to map immune and molecular changes in pregnancy, integrating these data with transcriptomics and mouse models. Her team studies how antidepressants affect immune signaling during pregnancy and examines the impact of social and behavioral factors. These insights may reveal biomarkers and therapeutic targets for improving maternal and fetal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40773]
Ina Stelzer, Ph.D., explores how the maternal immune system adapts to support a healthy pregnancy and how disruptions can lead to complications like preterm birth. Her lab identifies early immune changes linked to spontaneous preterm birth and investigates the role of the maternal brain in regulating immune responses. Stelzer uses advanced technologies like mass cytometry and spatial proteomics to map immune and molecular changes in pregnancy, integrating these data with transcriptomics and mouse models. Her team studies how antidepressants affect immune signaling during pregnancy and examines the impact of social and behavioral factors. These insights may reveal biomarkers and therapeutic targets for improving maternal and fetal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40773]
Ina Stelzer, Ph.D., explores how the maternal immune system adapts to support a healthy pregnancy and how disruptions can lead to complications like preterm birth. Her lab identifies early immune changes linked to spontaneous preterm birth and investigates the role of the maternal brain in regulating immune responses. Stelzer uses advanced technologies like mass cytometry and spatial proteomics to map immune and molecular changes in pregnancy, integrating these data with transcriptomics and mouse models. Her team studies how antidepressants affect immune signaling during pregnancy and examines the impact of social and behavioral factors. These insights may reveal biomarkers and therapeutic targets for improving maternal and fetal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40773]
Ina Stelzer, Ph.D., explores how the maternal immune system adapts to support a healthy pregnancy and how disruptions can lead to complications like preterm birth. Her lab identifies early immune changes linked to spontaneous preterm birth and investigates the role of the maternal brain in regulating immune responses. Stelzer uses advanced technologies like mass cytometry and spatial proteomics to map immune and molecular changes in pregnancy, integrating these data with transcriptomics and mouse models. Her team studies how antidepressants affect immune signaling during pregnancy and examines the impact of social and behavioral factors. These insights may reveal biomarkers and therapeutic targets for improving maternal and fetal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40773]
Ina Stelzer, Ph.D., explores how the maternal immune system adapts to support a healthy pregnancy and how disruptions can lead to complications like preterm birth. Her lab identifies early immune changes linked to spontaneous preterm birth and investigates the role of the maternal brain in regulating immune responses. Stelzer uses advanced technologies like mass cytometry and spatial proteomics to map immune and molecular changes in pregnancy, integrating these data with transcriptomics and mouse models. Her team studies how antidepressants affect immune signaling during pregnancy and examines the impact of social and behavioral factors. These insights may reveal biomarkers and therapeutic targets for improving maternal and fetal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40773]
This hour, Don Dubuc has a Bad Boy of the Week doubleheader and talks about some Vibrio vulnificus remedies. Then, Don gets field reports from Capt. Mike Gallo, Angling Adventures of Louisiana, Lance Burgos, and Capt. Ryan Lambert, President of Cajun Fishing Adventures.
Antibody-drug conjugates (ADCs) are a relatively new type of medicine for breast cancer. Enhertu (chemical name: fam-trastuzumab-deruxtecan-nxki) and Dato-DXd (brand name: Datroway) are two ADCs used to treat breast cancer. Dr Benjamin Schrank and colleagues have developed a new type of ADC that combines an antibody with a toxin — called an antibody-toxin conjugate — that teaches the immune system to recognize and attack cancer cells. Listen to the episode to hear Dr. Schrank explain: the antibody and the toxin component of the medicine how the new medicine works possible side effects next steps for the research Episode image photo credit: The University of Texas MD Anderson Cancer Center
In this episode, Dr. Jockers explores the shocking truth about saturated fat—how it can actually lower inflammation, protect your cells, and even reduce your risk of stroke. You'll learn how the right fats support hormone signaling, boost energy, and promote healthy aging. You'll discover the brain-enhancing power of medium-chain fats that fuel memory, mood, and cognition. These unique fats also spark mitochondrial growth and strengthen immune defenses in ways most people never expect. But not everyone benefits the same. Dr. Jockers explains who should be cautious with saturated fat, how genetics like the APOE4 gene and sluggish bile flow come into play, and what it means for your long-term health. In This Episode: 00:00 Introduction to Saturated Fats 03:30 Health Benefits of Saturated Fats 04:07 Understanding Oxidation and Inflammation 06:26 Saturated Fats and Brain Health 07:30 Saturated Fats and Immune System 08:31 Saturated Fats and Hormone Function 11:33 When Saturated Fats Can Be Problematic 13:18 Improving Bile Flow and Liver Health 14:56 Genetic Considerations: APOE4 Gene 16:48 Best Sources of Saturated Fats 20:07 Conclusion and Final Thoughts Are swollen legs or ankles slowing you down? Discover the power of Lymph System Support by Pure Health Research. Crafted with natural ingredients like dandelion extract, burdock root, and bromelain, this formula unclogs your lymphatic system, reducing swelling and supporting a healthy inflammatory response. As a special offer, try Lymph System Support risk-free today and receive a complimentary bottle of curcumin extract. Visit GetLymphHelp.com/jockers to claim yours now. Say hello to renewed vitality and goodbye to discomfort! Hair loss isn't just about age—it's about hair follicles getting stuck. AnaGain Nu by Purality Health uses a pea sprout extract clinically shown to reactivate follicles and boost regrowth. With their micelle liposomal delivery, your body absorbs it fast and effectively. Try it risk-free with a 180-day money-back guarantee and get a buy-one-get-one-free deal at RenewYourHair.com/DRJ. “Chronic disease starts with oxidation—saturated fat helps shut it down.” ~ Dr. Jockers Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: GetLymphHelp.com/jockers Visit https://renewyourhair.com/drj Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
In this episode of Rx for Biotech, host Chris Leidli sits down with Dr. Frank Bedu-Addo, CEO of PDS Biotechnology, to discuss how the company is reimagining immunotherapy with its proprietary Versamune® T-cell activating platform.
View the Show Notes For This Episode Dr. Nasha Winters discusses The Metabolic Theory of Cancer with Dr. Ben Weitz. Integrative Approaches to Cancer: Metabolic Theories and Personal Journeys In this episode of the Rational Wellness Podcast, hosted by Dr. Ben Weitz, the guest is Dr. Nasha Winters, a naturopathic doctor and integrative oncology specialist. The discussion centers around the integrative approach to cancer, including Dr. Winters' personal journey with ovarian cancer and her insights on the metabolic theory of cancer as opposed to the somatic mutation theory. They explore various factors influencing cancer, such as diet, environmental toxins, and mental health. Dr. Winters also shares information on innovative diagnostic tools, the importance of metabolic health, and her work in educating the public and healthcare providers. The conversation emphasizes that individual treatments should be tailored to the patient's unique metabolic and epigenetic profile. 00:26 Guest Introduction: Dr. Nasha Winters 01:55 Current State of Cancer Worldwide 03:56 Historical Context of Cancer and Health 12:07 Advancements in Cancer Diagnostics 20:30 Dr. Nasha Winters' Personal Health Journey 29:28 The Metabolic Theory of Cancer 36:24 Reevaluating Cancer Theories 38:20 Metabolic Approach to Cancer 39:08 Impact of Diet and Environment 40:23 Microbiome and Immune System 42:37 Radiation and Metabolic Health 52:12 Supplements and Immune Support 59:00 Personalized Cancer Treatment 01:07:10 Integrative Oncology and Future Directions ________________________________________________________ Dr. Nasha Winters is a licensed Naturopathic Doctor and an Integrative oncology specialist. She is the host of the Metabolic Matters podcast and Executive Director of the nonprofit organization, the Metabolic Terrain Institute of Health. And she is also a cancer survivor herself. Dr. Winters has a vision to open a residential integrative oncology hospital and research institute and she recently opened a metabolic research lab. She offers the Terrain Advocate program and the Metabolic Approach to Cancer practitioner master course. Dr. Nasha is a co-author of the best-selling books “The Metabolic Approach to Cancer” and Mistletoe and the Emerging Future of Integrative Oncology. Her website is DrNasha.com. Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.
Send us a textIn this episode, I'm walking you through the five body systems I assess in every autoimmune case — because supporting the immune system alone rarely leads to lasting results.We'll explore how dysfunction in the gut barrier, lymphatic system, detoxification pathways, microbiome, and nervous system can each contribute to flare-ups, immune confusion, and long-term inflammation — and more importantly, what you can do to start restoring balance.I also share some of my own experience with nervous system dysregulation — and why trauma, high-achieving burnout, and being constantly “switched on” can play such a pivotal role in triggering autoimmune disease.Whether you're new to this journey or deep in the layers, this episode will give you a clear, practical framework for moving forward.
Dr. Hoffman continues his conversation with Dr. Robert Silverman, author of "Immune Reboot: Maximizing Immunity, Restoring Gut Health, and Optimizing Vitality."
Dr. Robert Silverman, author of "Immune Reboot: Maximizing Immunity, Restoring Gut Health, and Optimizing Vitality," provides a comprehensive primer on the immune system. He explains how lifestyle factors—diet, sleep, exercise, and stress—impact immune resilience. He offers specific protocols for optimizing resistance to Covid, what to do if you come down with it, and how to treat Long Covid, as well as how to prepare for vaccines.
Send us a textThe appendix's hidden role and how "good" parasites like helminths shape immune health.Episode Summary: Dr. William Parker discusses gut anatomy, the appendix's role in harboring beneficial bacterial biofilms and immune tissue, and how modern hygiene depletes helminths (intestinal worms), causing immune overreactions like allergies, autoimmunity, and psychiatric conditions. He explores helminth self-therapy for treating relapsing MS, depression, and allergies; challenges in clinical trials due to patent issues; and why COVID-19 was milder in low-income, helminth-rich regions.About the guest: William Parker, PhD conducted research at Duke University for over 27 years on immunology, appendicitis, and the hygiene hypothesis. After retiring from Duke, he serves as a visiting scholar at the University of North Carolina at Chapel Hill, leading efforts on biome reconstitution via helminths.Discussion Points:Appendix is not vestigial; it concentrates immune tissue and biofilms to cultivate good gut bacteria, preventing pathogens via mucus and IgA antibodies.Hygiene hypothesis: Soap, toilets, and clean water reduce helminths/protozoa, leading to untrained, hyperactive immunity and rising allergies/autoimmunity since the 1800s.Helminths (worms) stimulate immune "exercise," training immunity; biohackers use hookworms (cheap, skin-entry), porcine whipworms, or rat tapeworms orally for relief from allergies, MS flares, depression/anxiety.Effects are temporary; need ongoing exposure (e.g., replenish every 6 months); immigrants from helminth-rich areas develop Western diseases within a few years.COVID-19: Hyper-immunity caused severe reactions in hygienic West, but helminth presence in low-income Africa/Asia prevented cytokine storms, leading to empty clinics.Therapy barriers: Non-patentable organisms require $100M+ trials; push for open-source, government-funded biome restoration over crude immunosuppressants.Related episode:M&M 144: Inflammation, Innate Immunity, Allergies & Allergens, Immune System Evolution, Fasting & Metabolism | Clare Bryant*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts
Report shows rapid declines in health of children and adolescents since 2007; N-acetylcysteine (NAC) for Parkinson's; Statins increase likelihood of hearing loss, tinnitus; Lithium orotate for Alzheimer's; Is tinnitus reversible? Novel implantable electrical vagus nerve stimulator approved for treatment of rheumatoid arthritis.
We're bombarded by stress every day, including pollution, UV rays, chemicals in food, household and personal care products, as well as physical and emotional challenges. Glutathione is the body's first line of defense against these stressors, helping to strengthen our ability to ward off the free radical attacks and oxidative damage they cause. Pharmacist Dr. Nayan Patel is discussing this nutrient with me and explaining why it's so important. Key Takeaways To Tune In For: (04:40) - Glutathione and Liver Health (08:00) - Glutathione's Role in the Immune System (10:30) - The Unique Delivery Technology (15:00) - Clinical Observations and Patient Experiences (19:00) - Glutathione for Specific Conditions (29:00) - Identifying the Need for Glutathione Resources talked about in this episode: Website: https://aurowellness.com/ Social media handles: IG FB TikTok YouTube
Today, hosts Tiffany and Katja discuss current research on female hormones, the immune system, and exercise. Both the female hormones as well as the immune function are intricate systems – bringing them together adds even more complexity! In this episode, we try to boil down the immune system and inflammatory response and explore recent research that sheds light on the relationship between the menstrual cycle, immune responses and exercise. We also discuss the nuances of inflammatory processes, individualised responses, and potential implications for peri- and post-menopause. Listen in as we talk about the influence of female hormones on immune processes and share why inner wisdom is an important part of understanding our bodies better. — Show Notes: Disclaimer – complexity of the immune system and menstrual cycle research [1:52] Inflammation and the immune system – bird's eye view [4:18] Influence of female hormones on immune and inflammatory processes [6:47] Potential changes in the second phase of the menstrual cycle [14:16] Current meta-analysis and systematic review on female hormones and immune function/ inflammation [15:43] Relationship with exercise [22:41] Current state of menstrual cycle-based training research [29:33] — Links Mentioned: Watch this episode on YouTube Female Hormones & Immune System References Doc Female Health Yoga Teacher Training Menopause Yoga Teacher Training Connect with Katja Bartsch: Facebook | Instagram | Kalamana Yoga | Yoga Medicine® Online Guest Teacher You can learn more about this episode, and see the full show notes at YogaMedicine.com/podcast-142. And you can find out more about insider tips, online classes or information on our teacher trainings at YogaMedicine.com. To support our work, please leave us a 5 star review with your feedback on iTunes/Apple Podcasts.
Join Dr. Eric Balcavage as he explores the critical relationship between gut health and thyroid function with registered dietitian and microbiome expert Kara Siedman. This episode dives deep into how your microbiome - the collection of bacteria, fungi, and viruses living in your gut - directly impacts thyroid physiology and overall health. Kara breaks down the complex science into actionable insights, explaining how gut dysbiosis can trigger thyroid dysfunction through inflammatory pathways, intestinal permeability, and disrupted hormone conversion. You'll discover why digestive symptoms aren't always present even when gut dysfunction is driving thyroid issues, and learn practical strategies for supporting your microbiome through diet, lifestyle, and targeted interventions. Key topics include: The role of short-chain fatty acids, The truth about probiotic supplementation How to evaluate microbiome health The connection between GLP-1 production and metabolic function. Whether you're dealing with Hashimoto's, hypothyroidism, or other chronic conditions, this episode provides the foundational knowledge you need to understand why gut health is often the missing piece in thyroid recovery. Kara Siedman, RDN, CDCES is a registered dietitian and certified diabetes care and education specialist with over 15 years of clinical experience in inpatient care, outpatient program development, and integrative/functional nutrition. She earned her degree from the University of Massachusetts Amherst and completed her dietetic internship at Cal Poly San Luis Obispo. Kara's work in a leading gastroenterology practice sparked her transition into functional nutrition, where she integrated root-cause approaches into GI care and became a mentor and key opinion leader in the field. Her passion for the gut microbiome evolved into a professional specialty, leading her to collaborate with biotech and microbiome-focused companies like Pendulum, Microbiome Labs, and now Resbiotic. As Director of Partnerships at resbiotic, Kara educates healthcare providers on microbiome science and the clinical application of targeted microbiome therapies. Known for her ability to simplify complex research, she brings clarity, credibility, and passion to gut health education. https://resbiotic.com/
In this Episode of Barbell Shrugged: What is the immune system Why the immune system is responsible for building muscle How gut health impacts the immune system Understanding recovery and its impact on the immune system How to optimize your immune system for performance Visit https://rapidhealthoptimization.com Connect with our guests: Anders Varner on Instagram Doug Larson on Instagram Coach Travis Mash on Instagram Dan Garner on Instagram
We may not often stop to think about it, but our water, food, furniture and other ordinary items are frequently contaminated with toxic chemicals. In this episode, Dr. Aly Cohen describes these threats to our health. You may have heard of compounds that can disrupt hormonal balance (endocrine disruptors). Everyday toxins like these can also […]
Dr. Hoffman continues his conversation with Dr. Jeffrey Bland, a pioneer in the field of integrative and functional medicine.
Dr. Jeffrey Bland, a pioneer in the field of integrative and functional medicine, discusses his latest project, Big Bold Health, which focuses on immune system rejuvenation through natural products like HTB (Himalayan Tery Buckwheat) and high-quality fish oil. The conversation delves into the origins and benefits of functional medicine, the importance of diet and lifestyle in health, and the concept of making America healthy. Dr. Bland also shares insights into his journey and the influence of traditional medicine practices. Listeners are encouraged to explore more about functional medicine and Big Bold Health's unique offerings.
If you've been struggling with brain fog, anxiety, irritability, or just not feeling like yourself in midlife, this episode is here for you to connect the dots. I'm shining a light on a hidden transition that impacts so many midlife women—but almost no one mentions it: the neurological shift of perimenopause. I share my own experience of feeling completely destabilized by brain-related symptoms I never expected—and how I finally discovered they were actually part of a profound brain-hormone transition happening under the surface. Then we cover the real science behind what's happening in your head, and why your symptoms are valid AND can be managed with the right tools in place. Tune in to this episode to get my top non-negotiables for a healthier brain, and tackle midlife sharper, stronger, and more fully YOU than ever! IN THIS EPISODE Why are brain-related symptoms so common during menopause? The impact that hormonal changes have on all body systems Two incredible perimenopause and menopause resources for you What goes on at a cellular level in the brain during menopause Top science-backed strategies for improving brain function How to join my FREE perimenopause and menopause summit! QUOTES“When I recently surveyed several thousand women in perimenopause about their most disruptive symptoms, something fascinating emerged. Yes, weight gain was on that list– it always is. But what stood out the most was the brain-related symptoms, the mood issues, the low or zero stress tolerance, and that terrifying feeling that your mental energy just vanished.” “If you want to get back to feeling stronger, more confident, more like yourself, again, it really begins with understanding what is happening with your body and embracing it.” “For decades, perimenopause holds the highest risk for psychological disorders in women compared to pre- and post-menopausal women. In fact, one study found that 70% of women said irritability is [their] most common symptom.” RESOURCES MENTIONED Preorder my new book: The Perimenopause Revolution HERE Join my FREE Thriving in Perimenopause and Menopause Summit HERE (Plus get my Hormone Loving Recipe Guide FREE!) Use code ENERGIZED and get 20% OFF on your first order of BEAM Minerals RELATED EPISODES Check out these episodes with a few amazing experts who are part of my Perimenopause and Menopause Summit: 584: The Health Costs of Our Modern Life & How to Start Feeling Better with Dr. Casey Means #552: The Midlife Muscle Crisis: Why Maintaining Muscle Is Necessary For Fat Loss, Strength and Longevity with Dr. Gabrielle Lyon #506: Optimizing Testosterone, Growth Hormone and Other Metabolic Hormones in Our 40s and Beyond with Dr. Stephanie Estima #574: The Connection between Trauma, the Immune System, and Autoimmune Disease: Lab Testing and Solutions with Dr. Sara Szal Gottfried
Many people with autoimmune conditions like lupus, Hashimoto's, or rheumatoid arthritis feel discouraged, confused and frustrated. They've been told there's nothing they can do except manage symptoms for the rest of their life. But what if autoimmune disease is associated with childhood and a sign that the body has been living in survival mode for too long and that recovery is possible? In this episode, Dr. Aimie explains the real nervous system root causes of autoimmune diseases and why rewiring your nervous system, stored trauma, and emotional pain can help your body recover. She shares her own story of sitting in a rheumatologist's office, staring at high antibody numbers on her lab results, and deciding there had to be a better way forward. You'll hear why autoimmune conditions often affect high-functioning women and how toxic stress and trauma from years ago can get stuck in the body, leading to fatigue, chronic pain, brain fog, and autoimmune flare-ups decades later. Dr. Aimie breaks down how autoimmunity isn't just about the immune system. It's also about safety, authenticity, and how the body responds to stress. Healing requires more than food or supplements. It means creating safety in your mind, in your body, and in your biology. In this episode, you'll hear more about: [2:10] Why reversing autoimmune symptoms is about more than lab results or medication [5:00] The personality traits that often show up in people with autoimmune conditions [9:30] How childhood stress, emotional pain, and trauma get stored in the body [13:40] Why a stressed nervous system leads to fatigue, brain fog, and chronic inflammation [18:00] The surprising connection between being your true self and autoimmune flare-ups [22:45] Why positive thinking alone doesn't work and what your body actually needs to heal [27:00] The three key levels of healing [31:00] First steps you can take to start nervous system regulation and feeling safe again Whether you're personally living with an autoimmune condition or you're a practitioner supporting clients with these challenges, this episode will give you the tools to start addressing the emotional root causes of autoimmunity and creating a felt sense of safety to help the body recover naturally. Guides, Tools & Resources: Biology of Trauma book - how the body experiences and holds fear, pain and overwhelm, and how to heal. Pre-order now and, at the time of this recording, you'll get over $400 in bonuses included! Those bonuses are only for the pre-order window which goes until Sept 22, 2025. When you've already pre-ordered it on Amazon head over here to receive your bonuses. The Foundational Journey - a 6 week program to change an inner Biology of Trauma. If you are looking for emotional regulation, nervous system healing and changes in your physical health without another pill, this is for you. If you are a practitioner - this is where to start with the certificate training to become a Biology of Trauma® professional. Related Podcast Episodes: Episode 55: Autoimmunity and Trauma in Chronic Conditions like Multiple Sclerosis Episode 71: Understanding the Trauma Connection Between Attachment, Autoimmunity, and Fatigue To Find Our Way Out Disclaimer: By listening to this podcast, you agree not to use this podcast as medical, psychological, or mental health advice to treat any medical or psychological condition in yourself or others. This podcast is for informational and educational purposes only and does not constitute professional advice, diagnosis, or treatment. Always consult your own physician, therapist, psychiatrist, or other qualified health provider regarding any physical or mental health issues you may be experiencing. This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Trauma Healing Accelerated, any guests or contributors to The Biology of Trauma® podcast, or any employees, associates, or affiliates of Trauma Healing Accelerated be responsible for damages arising from the use or misuse of the content provided in this podcast.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Eric Verdin is a physician-scientist and the CEO of the Buck Institute for Research on Aging whose career has centered on understanding how epigenetics, metabolism, and the immune system influence the aging process. In this episode, Eric traces his scientific journey from studying viruses and histone deacetylases (HDACs) to leading aging research at the Buck Institute, offering insights into how aging impairs immune and nervous system function—including thymic shrinkage, chronic inflammation, and reduced vaccine response—and how these changes impact lifespan. He explores the metabolic underpinnings of aging, such as oxidative stress and insulin and IGF-1 signaling, and he discusses practical tools like zone 2 cardio, ketogenic diets, and GLP-1 drugs. The conversation also covers declining NAD levels with age, the roles of NAD-consuming enzymes such as sirtuins and CD38, and what current NAD-boosting strategies (like NMN, NR, and IV NAD) can and can't accomplish. Eric weighs in on promising longevity interventions including rapamycin, growth hormone for thymic regeneration, and anti-inflammatory therapies, while also examining the promise and limitations of current biological age tests and the potential of combining epigenetic, proteomic, and organ-specific metrics with wearables to guide personalized longevity care. We discuss: Eric's scientific journey from virology to the field of geroscience [2:45]; How dysfunction in the immune system and central nervous system can drive aging throughout the body [5:00]; The role of metabolism and oxidative stress in aging, and why antioxidant strategies have failed to deliver clear benefits [8:45]; Other aspects of metabolism linked to aging: mitochondrial efficiency, fuel utilization, and glucose-modulating drugs [16:30]; How inefficient glucose metabolism drives insulin, IGF-1 signaling, and accelerates aging [21:45]; The metabolic effects of GLP-1 agonists, and the need to move beyond crude metrics like BMI in favor of more precise assessments of metabolic health [27:00]; The case for immune health as a “fifth horseman” [36:00]; How the innate and adaptive immune systems work together to build immune memory [39:45]; Why vaccines lose effectiveness with age: shrinking of the thymus gland and diminished T-cell diversity [44:15]; Exploring growth hormone, thymic regeneration, and the role of exercise in slowing immune aging [48:45]; The challenges of identifying reliable biomarkers for immune function, and the potential of rapamycin analogs to enhance vaccine response in older adults [57:45]; How rapamycin's effects on the immune system vary dramatically by dosage and frequency [1:03:30]; The limitations of mouse models in aging research and the need for cautious interpretation of rapamycin's benefits in humans [1:08:15]; NAD, sirtuins, and aging: scientific promise amid commercial hype [1:15:45]; How CD38 drives age-related NAD decline, influences immune function, and may impact longevity [1:23:45]; How NMN and NR supplementation interact with CD38 and NAD metabolism, and potential risks like homocysteine elevation and one-carbon cycle depletion [1:31:00]; Intravenous NAD: limited evidence and serious risks [1:37:00]; Interleukin-11 (IL-11) as a new target in immune aging, the dual role of chronic inflammation in aging, and the need for better biomarkers to guide interventions [1:43:00]; Biological aging clocks: types of clocks, promise, major limitations, and future outlook [1:48:30]; The potential of proteomics-based aging clocks for detecting organ-specific decline and frailty [2:00:45]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
Spending time in nature feels good—but what if it could also strengthen your immune system in a powerful way? On today's episode, I want to share with you some fascinating research on a simple activity that can significantly increase natural killer (NK) cells, helping your body fight off viruses, reduce inflammation, and even protect against cancer. So join me on today's Cabral Concept 3464 to learn how you can boost your immune system by up to 80% in just 3 days. Enjoy the show—and as always, I'd love to hear your thoughts! - - - For Everything Mentioned In Today's Show: StephenCabral.com/3464 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!