Podcasts about markers

You might not realize just how much your oral health is tied to your heart and overall wellness—but it's a connection worth knowing about. I caught up again with my amazing colleague, Dr. Ellie Campbell, and we got into why regular lab tests sometimes miss the early signs of things like heart disease, stroke, and even dementia. We talked about why your dentist could actually be one of the most important people on your health team, plus some sneaky risks that only advanced testing can catch. Dr. Ellie has been in family medicine for over 25 years, mixing integrative and functional approaches to help people truly understand their health. She shared some eye-opening stuff about how sleep apnea can mess with your blood sugar, why fasting blood sugar numbers matter more than you think, and how your genes could be playing a bigger role than you realize. She also gave some solid advice on how to speak up for yourself in a medical system that doesn't always connect these dots. If you're someone who wants to take better care of yourself and catch problems before they sneak up, this episode is packed with tips that really hit home. And by the way, just to sweeten things up—my new Mighty Maca Mango is out now, perfect for spring and summer. It's a delicious twist on Mighty Maca that you can toss in sparkling water or make into popsicles. Check it out anytime at dranna.com—it's a little treat with big benefits.   Key Timestamps: [00:00:00] Introduction. [00:04:54] How to know if you have cardiovascular disease. [00:10:09] Corrupted LDL cholesterol explained. [00:11:32] Oxidative stress and antioxidants. [00:15:54] Gender differences in blood sugar. [00:20:20] Increased mortality with very low blood sugar. [00:24:21] Continuous glucose monitors' impact. [00:28:56] LDL cholesterol management post-heart attack. [00:32:03] Markers of oxidative stress. [00:36:43] ApoE4 gene and health risks. [00:39:57] 2 recommended radiology tests for patients over 40. [00:46:13] Atherosclerosis awareness and prevention.   Memorable Quotes: "People with the highest cholesterol live the longest. You heard that right." [00:10:30] – Dr. Ellie Campbell "I believe that we saved that patient from a heart attack or a stroke by identifying leading indicators in blood that told me she had a dental problem that took three dentists to find." [00:34:21] – Dr. Ellie Campbell   Links Mentioned: Mighty Maca Mango: https://drannacabeca.com/products/mighty-maca The Blood Pressure Blueprint: https://bpblueprint.com/   Connect with Dr. Ellie Campbell: Website: https://www.campbellfamilymedicine.com/ Instagram: https://www.instagram.com/ellie.cfm/   Connect with Dr. Anna Cabeca: Website: https://drannacabeca.com/pages/show Instagram: https://www.instagram.com/thegirlfrienddoctor/ YouTube: https://www.youtube.com/@thegirlfrienddoctor TikTok: https://www.tiktok.com/@drannacabeca   Produced by Evolved Podcasting: www.evolvedpodcasting.com

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In this episode, Ed Frawley shares why and how we teach the hand touch skill to your dog. The Hand Touch is a foundational skill taught in basic and intermediate dog obedience to teach the dog to engage with the handler by pressing their nose into the palm of your hand. | Links mentioned: Basic Dog Obedience: https://leerburg.com/302.htm | Intermediate Dog Obedience: https://leerburg.com/302b.php | The Power of Training Dogs with Markers: https://leerburg.com/marker-dvd.php | Training Dogs with Food Rewards: https://leerburg.com/food-dvd.php | Obedience Training Equipment: https://leerburg.com/view-category.php?categoryid=699

Kalea Wattles, ND, IFMCP, is a naturopathic physician and functional medicine practitioner specializing in fertility optimization. Currently serving as the Clinical Special Projects Manager at The Institute for Functional Medicine, where she has been on staff since 2017, she is committed to the advancement of the field through research and education. She is the host of IFM's podcast Pathways to Well-Being. Dr. Wattles earned her doctorate in naturopathic medicine from Bastyr University, where she developed a keen interest in functional medicine. She went on to receive additional training from The Institute for Functional Medicine, where she further honed her skills in a root-cause, science-based, body-systems approach to healthcare.   In this episode of Conversations For Health, we explore how Dr. Kalea applies a functional medicine lens to fertility, highlighting the clinical relevance of mitochondrial health, oxidative stress, inflammaging, and more when it comes to female and male fertility. We discuss the narrative of the fertility cliff, how to assess diminished ovarian reserve even in patients in their 20s, and how to interpret AMH values in context. Our conversation is filled with actionable insights into preconception care protocols, fertility focus, lab interpretation, and how to personalize support for patients preparing for IVF or egg freezing.   I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.   Episode Resources: Dr. Kalea Wattles - https://drkaleawattles.com/ Design for Health Resources: Designs for Health - https://www.designsforhealth.com/ Designs for Health Practitioner Exclusive Drug Nutrient Depletion and Interaction Checker - https://www.designsforhealth.com/drug-nutrient-interaction/ Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog. https://www.designsforhealth.com/research-and-education/education The Designs for Health Podcast is produced in partnership with Podfly Productions. Chapters: 00:00 Intro. 02:02 Dr. Kalea is delighted about the current headlines about fertility into the 40s. 03:40 Dr. Kalea's journey into motherhood aligned with her professional focus. 06:50 AMH is the top trending biomarker in ovarian reserve. 11:41 Markers to consider in relation to oxidative stress and inflammation. 16:02 Top tier oxidative stress markers, including 8-OHdG and F2-IsoP. 18:54 The importance of mitochondrial health in ovarian health, egg quality and sperm. 23:50 DNA fragmentation and other potential findings from a semen analysis. 27:00 Shifts in the fertility conversation in recent years. 31:01 CoQ10 and melatonin recommendations that Dr. Kalea implements with her patients. 37:09 The role of glutathione in protecting against oxidative stress. 39:50 Dr. Kalea's personal experience with ovarian age testing. 43:05 Cycle Day 3 hormone measurements, including DHEA sulfate and prolactin. 49:32 Diet, environment, and other major factors in diminished ovarian reserve. 53:01 Redefining unexplained infertility. 55:06 Androgens and the impacts on eggs. 57:11 Ideal DHEA and testosterone levels. 1:00:05 The vaginal microbiome, gut health, and urea plasma. 1:03:10 Dr. Kalea's favorite personal supplements, favorite health practices, and the maternal fertility limits that she has changed her mind about.

In this episode, Ed Frawley shares why and how we teach the collar grab skill to your dog. The Collar Grab is a foundational skill taught in basic and intermediate dog obedience to teach the dog how to be comfortable with being grabbed and led by the collar. | Links mentioned: Basic Dog Obedience: https://leerburg.com/302.htm | Intermediate Dog Obedience: https://leerburg.com/302b.php | The Power of Training Dogs with Markers: https://leerburg.com/marker-dvd.php | Training Dogs with Food Rewards: https://leerburg.com/food-dvd.php | Obedience Training Equipment: https://leerburg.com/view-category.php?categoryid=699

At NAB Show 2025, Thomas Ribreau, Chief Product Officer and Co-Founder for Cyme demos the features of Peakto, a local AI-powered media asset management tool. Peekto allows users to search video and photo content by text, metadata, facial recognition, and timeline. It integrates with tools like Final Cut and Adobe Premiere, supports secure local and remote sharing, and offers collaborative editing—all without cloud dependency.  Show Notes: Chapters: 00:08 NAB Show 2025 Introduction 01:29 Exploring Peakto Software 05:30 Advanced Search Features 07:42 Rendering and Categorization 08:54 Using Bins and Markers 11:52 Sharing and Collaboration 14:20 Remote Access Capabilities 18:05 Pricing and Conclusion Support:      Become a MacVoices Patron on Patreon      http://patreon.com/macvoices      Enjoy this episode? Make a one-time donation with PayPal Connect:      Web:      http://macvoices.com      Twitter:      http://www.twitter.com/chuckjoiner      http://www.twitter.com/macvoices      Mastodon:      https://mastodon.cloud/@chuckjoiner      Facebook:      http://www.facebook.com/chuck.joiner      MacVoices Page on Facebook:      http://www.facebook.com/macvoices/      MacVoices Group on Facebook:      http://www.facebook.com/groups/macvoice      LinkedIn:      https://www.linkedin.com/in/chuckjoiner/      Instagram:      https://www.instagram.com/chuckjoiner/ Subscribe:      Audio in iTunes      Video in iTunes      Subscribe manually via iTunes or any podcatcher:      Audio: http://www.macvoices.com/rss/macvoicesrss      Video: http://www.macvoices.com/rss/macvoicesvideorss

In this episode, Ed Frawley shares a question from the Ask Cindy database. Today's question is about applying to become a K9 handler and building a relationship with a working K9. | Links mentioned: Developing a Relationship with Your Dog with Michael Ellis: https://university.leerburg.com/Catalog/viewCourse/cid/159 | Behavior Creation with Michael Ellis: https://university.leerburg.com/Catalog/viewCourse/cid/236 | Engagement with Michael Ellis: https://university.leerburg.com/Catalog/viewCourse/cid/176 | Food Chase Games: https://university.leerburg.com/Catalog/viewCourse/cid/175 | Training Dogs with Food Rewards: https://university.leerburg.com/Catalog/viewCourse/cid/206 | The Power of Training Dogs with Markers: https://university.leerburg.com/Catalog/viewCourse/cid/96 | The Power of Training Dogs with Food: https://university.leerburg.com/Catalog/viewCourse/cid/84

Dr. Orit Wimpfheimer, Chief Medical Officer at Nanox, a medical imaging AI company using technology to detect early signs of diseases through opportunistic screening of CT scans. The AI platform identifies signs of diseases such as osteoporosis and cardiovascular disease that may have been overlooked by the radiologist. The tools are designed to be integrated into the radiologist's workflow to provide quantified measurements to guide clinical care decisions leading to improved patient outcomes.   Orit explains, "The number of CT scans over the last 20 years has risen astronomically. People are getting CT scans for many reasons, and there's a lot of data on the images that doesn't get translated into patient care. And what our AI tools do is to scan all those CT scans in the background unobtrusively, so they look for signs of chronic conditions and highlight those to the radiologists while they're reading the scans. This ensures that chronic diseases are commented on in the reports, initiating a clinical pathway to help treat those diseases at the early stages of their disease processes. Ultimately, we're trying to find diseases much earlier to treat them much better and therefore increase the quality of life and the length of life by treating these diseases before they become very symptomatic." "So our tools are actually measurement tools. When the radiologist looks at the images, they have their checklist in their mind, myself included. I'm a radiologist. Things we're always looking for on the scan, and then we pay attention based on the patient's clinical history or rule out pneumonia, rule out cancer, whatever it is. Sometimes these chronic diseases might be lurking in the background, but they don't get attention from the radiologist. And even if the radiologist is super careful and tries to find everything on the exam, we don't have time to start measuring things. And when you comment on something without giving a quantified measurement, it's very hard for the clinician down the line to know what to do with this patient. It's too vague. When we give quantified information, the doctor, after the radiologist, can take that quantified information and then know where to send the patient next and what to do next with the patient. And that's critical because we don't want to drop patients along the way, the clinical care pathway, because then it's ineffective." #NanoxVision #AIinHealthcare #HealthcareAI #MedAI #RadiologyAI #HealthcareInnovation #Medical Imaging #Radiology #EarlyDetection #PreventiveCare #PatientCare  nanox.vision Download the transcript here

In this episode of The Hole Story Podcast, Robby sits down with Boring Brandon from Boring Ball Markers—a company that's anything but dull, despite the name. Brandon shares the quirky origin story of Boring Ball Markers, from an impulse ad buy before the company even existed, to launching a line of unique ball markers that break the typical “boring” mold. We get an inside look at Brandon's lifelong relationship with golf, his partnership with co-founder Alex, and how their business is growing in an ever-more creative and expressive golf world.You'll hear about the challenges and successes in starting a golf accessory brand, the creative process behind their custom markers, and how Boring Ball Markers found their way onto both amateur greens and the professional tours. Plus, Brandon talks memorable golf shots, dream foursomes, and why the community side of golf means so much to him.If you've ever wondered how a simple idea can become a standout brand—or you're just here for the stories behind the game you love—this episode is for you. So grab your putter, mark your ball, and let's dive into The Hole Story behind Boring Ball Markers!https://boringballmarkers.com/https://www.instagram.com/boringballmarkers/BestBall Links:•https://BestBall.com•https://linktr.ee/BestBall•https://bestball.substack.com - Subscribe to Par 3 Thursdays!Friends of BestBall:•B. Draddy - https://www.bdraddy.com - Enter "BESTBALL20" for 20% off your order•Zero Restriction - https://www.zerorestriction.com - Enter "BESTBALL20" for 20% off your order•Fairway & Greene - https://www.fairwayandgreene.com - Enter "BESTBALL20" for 20% off your order•Arccos Golf - https://bit.ly/4gXNDQi - Get 15% off your order•The Stack System - https://www.thestacksystem.com/discount/BestBall - Get 10% off your order•Western Birch - https://westernbirch.com - Enter "BESTBALL" in the shipping cart for a free gift with your order. Interested in becoming a sponsor of The Hole Story Podcast? Email info@bestball.com.

Every good show has a season in space. Welcome to the third season of Markers on the Map! If you're new to the show, we set the stage each season with some lore, and delve into this constantly-shifting game industry, from the latest and greatest to the almighty classics that paved the way. This week, we've got Switch 2 pre-order stories, some familiar season premiere Fall Guys talk, and the return of a classic segment for a limited time. And Plok. We can't forget Plok! We're also on BlueSky if you'd like to keep up with the show @MarkersOnTheMap.

Dr. Orit Wimpfheimer, Chief Medical Officer at Nanox, a medical imaging AI company using technology to detect early signs of diseases through opportunistic screening of CT scans. The AI platform identifies signs of diseases such as osteoporosis and cardiovascular disease that may have been overlooked by the radiologist. The tools are designed to be integrated into the radiologist's workflow to provide quantified measurements to guide clinical care decisions leading to improved patient outcomes.   Orit explains, "The number of CT scans over the last 20 years has risen astronomically. People are getting CT scans for many reasons, and there's a lot of data on the images that doesn't get translated into patient care. And what our AI tools do is to scan all those CT scans in the background unobtrusively, so they look for signs of chronic conditions and highlight those to the radiologists while they're reading the scans. This ensures that chronic diseases are commented on in the reports, initiating a clinical pathway to help treat those diseases at the early stages of their disease processes. Ultimately, we're trying to find diseases much earlier to treat them much better and therefore increase the quality of life and the length of life by treating these diseases before they become very symptomatic." "So our tools are actually measurement tools. When the radiologist looks at the images, they have their checklist in their mind, myself included. I'm a radiologist. Things we're always looking for on the scan, and then we pay attention based on the patient's clinical history or rule out pneumonia, rule out cancer, whatever it is. Sometimes these chronic diseases might be lurking in the background, but they don't get attention from the radiologist. And even if the radiologist is super careful and tries to find everything on the exam, we don't have time to start measuring things. And when you comment on something without giving a quantified measurement, it's very hard for the clinician down the line to know what to do with this patient. It's too vague. When we give quantified information, the doctor, after the radiologist, can take that quantified information and then know where to send the patient next and what to do next with the patient. And that's critical because we don't want to drop patients along the way, the clinical care pathway, because then it's ineffective." #NanoxVision #AIinHealthcare #HealthcareAI #MedAI #RadiologyAI #HealthcareInnovation #Medical Imaging #Radiology #EarlyDetection #PreventiveCare #PatientCare  nanox.vision Listen to the podcast here

Howie and Harlan are joined by Thomas Gill, a Yale geriatrician whose research tracks the factors that contribute to disability in older adults—and those that support continued independence. And they discuss the contrarian tapped to evaluate vaccines at the FDA, allegations of kickbacks against insurers, and the potential end of a loophole that has allowed states to collect additional Medicaid funding.  Links: Vinay Prasad at the FDA “Vinay Prasad tapped to run FDA center that regulates vaccines, gene therapies” “Vinay Prasad, in his own words, outlines the philosophy he'll bring to the FDA” “Peter Marks, FDA's top vaccine regulator, forced out” Howard Forman on LinkedIn on Vinay Prasad's Appointment Vinay Prasad's Substack Insurance News “Justice Department Sues Big Medicare Insurers Alleging Kickbacks” “Aetna to exit the ACA exchanges in 2026” “What Aetna quitting the exchanges says about the exchanges” ”CVS to boost access to Novo Nordisk's weight loss treatment Wegovy for patients on its drug plans” Thomas Gill Statista: Share of old age population (65 years and older) in the total U.S. population from 1950 to 2050 Thomas Gill: “A physical activity intervention to treat the frailty syndrome in older persons-results from the LIFE-P study” Thomas Gill: “A Program to Prevent Functional Decline in Physically Frail, Elderly Persons Who Live at Home” “Prehabilitation for Patients Undergoing Orthopedic Surgery: A Systematic Review and Meta-analysis” “Allostatic Load: Importance, Markers, and Score Determination in Minority and Disparity Populations” “Cohort Profile: The Precipitating Events Project (PEP Study)” “In Memoriam: Yale Expert in Clinical Research Methods, Alvan R. Feinstein” Medicaid Cuts “Putting $880 Billion in Potential Federal Medicaid Cuts in Context of State Budgets and Coverage” “Republicans are running out of ways to cut Medicaid as moderates and hard-liners clash” “G.O.P. Targets a Medicaid Loophole Used by 49 States to Grab Federal Money” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

You may start the morning like most people...stepping on the scale, but it doesn't give you insights into your health.

Howie and Harlan are joined by Thomas Gill, a Yale geriatrician whose research tracks the factors that contribute to disability in older adults—and those that support continued independence. And they discuss the contrarian tapped to evaluate vaccines at the FDA, allegations of kickbacks against insurers, and the potential end of a loophole that has allowed states to collect additional Medicaid funding.  Links: Vinay Prasad at the FDA “Vinay Prasad tapped to run FDA center that regulates vaccines, gene therapies” “Vinay Prasad, in his own words, outlines the philosophy he'll bring to the FDA” “Peter Marks, FDA's top vaccine regulator, forced out” Howard Forman on LinkedIn on Vinay Prasad's Appointment Vinay Prasad's Substack Insurance News “Justice Department Sues Big Medicare Insurers Alleging Kickbacks” “Aetna to exit the ACA exchanges in 2026” “What Aetna quitting the exchanges says about the exchanges” ”CVS to boost access to Novo Nordisk's weight loss treatment Wegovy for patients on its drug plans” Thomas Gill Statista: Share of old age population (65 years and older) in the total U.S. population from 1950 to 2050 Thomas Gill: “A physical activity intervention to treat the frailty syndrome in older persons-results from the LIFE-P study” Thomas Gill: “A Program to Prevent Functional Decline in Physically Frail, Elderly Persons Who Live at Home” “Prehabilitation for Patients Undergoing Orthopedic Surgery: A Systematic Review and Meta-analysis” “Allostatic Load: Importance, Markers, and Score Determination in Minority and Disparity Populations” “Cohort Profile: The Precipitating Events Project (PEP Study)” “In Memoriam: Yale Expert in Clinical Research Methods, Alvan R. Feinstein” Medicaid Cuts “Putting $880 Billion in Potential Federal Medicaid Cuts in Context of State Budgets and Coverage” “Republicans are running out of ways to cut Medicaid as moderates and hard-liners clash” “G.O.P. Targets a Medicaid Loophole Used by 49 States to Grab Federal Money” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

#ThrowbackThursday In the first of two episodes, Dr. Bahijja Raimi-Abraham interviews Professor Joseph Devlin about his work in consumer neuroscience and neuromarketing. They discuss the importance of understanding consumer behaviour and the ethical considerations surrounding data collection and use. They also touch on the topic of masculinity and its influence on consumer behaviour.

Could you be in perimenopause? Are you experiencing mood swings, trouble sleeping, or irregular cycles and wondering if it's just stress—or something more? In this week's episode, we're unpacking the hormonal rollercoaster that is perimenopause, a transitional phase that can span up to 10 years before menopause officially sets in. We talk about what's happening with your hormones during this time, how to assess where you're at, and the most common symptoms women face as their bodies shift. We also share empowering, food-as-medicine strategies, targeted supplements, and key lifestyle interventions to help you feel balanced, supported, and vibrant through the transition. Aging doesn't have to mean losing yourself in the process—there's so much you can do to stay sharp, energized, and grounded. Tune in and learn how to navigate perimenopause with clarity and confidence. Also in this episode:  Defining perimenopause Symptoms of perimenopause Conventional treatment of perimenopause symptoms Functional medicine approach Phytoestrogens Kudzu Red Clover Flax Turmeric Resveretrol I3C Broccodetox  Labs for perimenopause Dutch Hormone Panel Labrix Neurohormone Complete Plus Episode 395 Testing Women's Hormones LH, FSH, Estradiol (Day 3) Progesterone (Day 19) Cholesterol changes in perimenopause Episode 139 The Pregnenolone Steal Episode 433 Markers that Matter for Heart Health Priorities of supplementation Relax and Regulate Bio-C Plus Vitamin D Balanced Blend Women's Flora Julva Food as medicine  Mediterranean Keto Protein Episode 412 The Power of Protein Whey Protect Pure Collagen Fiber Omega 3s Bone Broth Fasting Carnitine Detox Packs Creatine    Sponsors for this episode:  This episode is sponsored by Wild Foods, a company that puts quality, sustainability, and health first in all of their products. They have everything from coffee to turmeric to medicinal mushrooms, and every single product is painstakingly sourced from small farms around the globe. They take their mission seriously to fix the broken food system, and believe real food is medicine. They've partnered with us to give you guys an exclusive discount, so use the code ALIMILLERRD for 12% off your order at WildFoods.co!   

Welcome to your one minute masterclass! To get the latest episodes first, subscribe to the DiscoverDance mailing list: https://discoverdance.us18.list-manage.com/subscribe?u=9d0eb3d3536d1544ab2f7979c&id=221ecffc19&fbclid=IwAR3nrjIxWTLLEb65jNpntPxm6EMlNqhuZNanQgSK51ZfXjsiFY2z4BAEGMo   Enjoy~ Andrea  

We apologize for the broken audio! The recording had a glitch, which required quite a bit of extra editing, as a result of the chaos, the cuts were tighter than expected, causing sentences to be cut short. This won't be a recurring issue, however! Thank you for your understanding and continued support!What's up Gamers?!In the latest episode of Konsole Kombat, the debate gets deadlier than ever as the hosts pit two legendary sci-fi warriors against each other: Halo's Rtas ‘Vadum and Dead Space's Isaac Clarke. Rtas ‘Vadum, the master tactician and revered Sangheili Shipmaster of the Shadow of Intent, brings his fearsome energy sword skills, battlefield cunning, and unmatched leadership to the arena. Isaac Clarke, the resourceful engineer, faces off with his arsenal of improvised weaponry and unyielding willpower, forged in the crucible of the Necromorph outbreak and his ongoing struggle with Marker-induced madness.Listeners journey through each contender's origins: from Rtas's home on Sanghelios and his pivotal role in the Great Schism, to Isaac's harrowing battles aboard the USG Ishimura and his haunting encounters with the Markers. The hosts examine their fighting styles, psychological resilience, and how they lead under extreme pressure. But this time, the Konsole Kombat Arbiter has something unexpected up his sleeve—a shocking twist that shakes up the matchup at the last moment. Who reigns supreme in this ultimate cross-universe showdown? Tune in to discover the verdict—and the surprise that will leave fans talking long after the credits roll!

Speakers- Fitz The post Relationship Matters – Boundary Markers appeared first on Okolona Christian Church.

BUFFALO, NY — April 29, 2025 — A new #research paper was #published in Aging (Aging-US) Volume 17, Issue 3, on March 20, 2025, titled “Inhibition of the metalloprotease ADAM19 as a novel senomorphic strategy to ameliorate gut permeability and senescence markers by modulating senescence-associated secretory phenotype (SASP).” Researchers, led by first author Sudipta Bar and corresponding authors Amit Sharma and Pankaj Kapahi from the Buck Institute for Research on Aging, have found that the enzyme ADAM19 plays an important role in regulating aging in cells and inflammation in the gut. Their study shows that blocking ADAM19 reduced gut damage and inflammation in fruit flies, mice, and human cells. This discovery points to a new possible way to treat gut disorders related to aging by reducing the harmful signals from senescent (aging) cells. As individuals age, DNA damage can lead to the accumulation of senescent cells, contributing to tissue damage. These are cells that stop dividing and release harmful inflammatory substances called the senescence-associated secretory phenotype (SASP). In this study, researchers used fruit flies to search for genes involved in radiation-related gut damage. They identified a gene called meltrin, which is similar to human ADAM19. When meltrin was turned off, the flies had less gut leakage, less inflammation, and fewer signs of cellular aging. “Through an unbiased genome-wide association study (GWAS) utilizing 156 strains from the Drosophila Genetic Reference Panel (DGRP), we identified meltrin (the drosophila orthologue of mammalian ADAM19) as a potential modulator of the senescence-associated secretory phenotype (SASP).” To test if these results applied beyond flies, the team inhibited ADAM19 in mice using a drug called batimastat. Mice treated with the drug after chemotherapy exposure had stronger gut barriers and lower levels of inflammatory markers. The findings extended to human cell cultures, where ADAM19 inhibition reduced signs of cellular aging, including the expression of SASP proteins and β-galactosidase, a classic aging marker. Importantly, this approach does not kill aging cells like many 'senolytic' therapies but instead reduces the harmful substances they release, making it a potential "senomorphic" strategy. The study also showed that ADAM19 helps release certain SASP proteins by cutting them at the cell surface, suggesting a direct role in regulating inflammatory signals. Through proteomic analysis, the team identified 12 SASP proteins that were significantly reduced when ADAM19 was blocked. Many of these proteins are linked to inflammation, immune response, and tissue remodeling in diseases such as inflammatory bowel disease and Crohn's disease. This connection underlines the relevance of the findings for treating chronic gut disorders in aging populations. By targeting ADAM19, researchers may have found a new way to protect gut health and lower inflammation caused by aging cells. This study offers a promising path for creating treatments that maintain healthy tissues without having to destroy aging cells, which could benefit people with gut damage related to aging or medical treatments. DOI - https://doi.org/10.18632/aging.206224 Corresponding authors - Amit Sharma - amit.sharma@sens.org, and Pankaj Kapahi - pkapahi@buckinstitute.org Video short - https://www.youtube.com/watch?v=dRfxQ20O2fQ Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts To learn more about the journal, please visit our website at https://www.Aging-US.com​​. MEDIA@IMPACTJOURNALS.COM

This week, Chris & Josh discuss the following topics (and so much more):   Tips, tricks and suggestions for new Vegas visitors Your longest Vegas walk When to pay back markers New show and spa recommendations Elaine Wynn   Want to contact us? Email: podcast@crapvegas.com Facebook: crapvegas.com/facebook Twitter: @VegasDuffy @SmallWhale13 @CrapVegas For more information, please visit our webpage at www.crapvegas.com or support us by becoming a Patreon subscriber at www.patreon.com/crapvegas  

As elite athletes it is important to get regular bloodwork done! But which markers are especially important for bikini competitors and why? When should you get your bloodwork done - before a bikini prep? After competition day? During your improvement season? In this episode we break it all down for you! Follow us on IG @preplifepodcast @glamgirlbikini @amyehinger @leemarie183    Join the team: https://www.glamgirlbikini.com/get-started/     1st Phorm Supplements we use: https://1stphorm.com/?a_aid=glamgirlbikini    Supplements discussed in this episode: Harmony: https://1stphorm.com/products/harmony/?a_aid=glamgirlbikini Vitamin D: https://1stphorm.com/products/liposomal-vitamin-d3/?a_aid=glamgirlbikini Magnesium: https://1stphorm.com/products/magnesium/?a_aid=glamgirlbikini  

"I am on a mission to show in the most positive manner just how far off a lot of these people are and to show people there's hope and to teach them how to do it without completely eradicating their health." - Dylan Gemelli I sat down with Dylan Gemelli, a prominent figure in the fitness and biohacking industry who's transitioned from the bodybuilding world to becoming a cellular health expert. Dylan shared his incredible journey of rebuilding his life from scratch, discovering peptides and SARMs long before they became mainstream, and his personal battle with heart disease that led him to prove medical professionals wrong about what's possible. We dive deep into the world of peptides, cardiovascular health testing beyond standard panels, and why the hierarchy of health should include strategic supplementation for optimal aging. Dylan's passion for challenging medical dogma is infectious, especially his evidence that LP(a) levels can be lowered despite conventional wisdom saying otherwise. What you'll learn: What peptides and SARMs are and how they differ from harmful substances like steroids Why standard cholesterol panels miss the most important cardiovascular risk markers How Dylan lowered his "unchangeable" LP(a) levels by over 230 points when doctors said it was impossible The hierarchy of health supplements everyone should consider, starting with creatine for women of all ages Why microdosing GLP-1s may be the ultimate longevity hack for improved metabolic health How specialized peptides can accelerate healing, improve sleep, and support cellular repair The truth about NAD+ supplementation and what delivery methods actually work Why building and maintaining muscle mass is critical as we age, especially for women Love the Podcast? Here's what to do: Make My Day & Share Your Thoughts! Subscribe to the podcast & leave me a review Text a screenshot to 813-565-2627 Expect a personal reply because your voice is so important to me. Join 50,000+ followers who make this podcast thrive. Want to listen to the show completely ad-free?  Go to subscribetojj.com Enjoy the VIP experience for just $4.99/month or $49.99/year (save 17%!) Click “TRY FREE” and start your ad-free journey today! Full show notes (including all links mentioned): https://jjvirgin.com/dylan Learn more about your ad choices. Visit megaphone.fm/adchoices

"I am on a mission to show in the most positive manner just how far off a lot of these people are and to show people there's hope and to teach them how to do it without completely eradicating their health." - Dylan Gemelli   I sat down with Dylan Gemelli, a prominent figure in the fitness and biohacking industry who's transitioned from the bodybuilding world to becoming a cellular health expert. Dylan shared his incredible journey of rebuilding his life from scratch, discovering peptides and SARMs long before they became mainstream, and his personal battle with heart disease that led him to prove medical professionals wrong about what's possible. We dive deep into the world of peptides, cardiovascular health testing beyond standard panels, and why the hierarchy of health should include strategic supplementation for optimal aging. Dylan's passion for challenging medical dogma is infectious, especially his evidence that LP(a) levels can be lowered despite conventional wisdom saying otherwise.   What you'll learn:   What peptides and SARMs are and how they differ from harmful substances like steroids Why standard cholesterol panels miss the most important cardiovascular risk markers How Dylan lowered his "unchangeable" LP(a) levels by over 230 points when doctors said it was impossible The hierarchy of health supplements everyone should consider, starting with creatine for women of all ages Why microdosing GLP-1s may be the ultimate longevity hack for improved metabolic health How specialized peptides can accelerate healing, improve sleep, and support cellular repair The truth about NAD+ supplementation and what delivery methods actually work Why building and maintaining muscle mass is critical as we age, especially for women   Love the Podcast? Here's what to do: Make My Day & Share Your Thoughts! Subscribe to the podcast & leave me a review Text a screenshot to 813-565-2627 Expect a personal reply because your voice is so important to me. Join 50,000+ followers who make this podcast thrive. Want to listen to the show completely ad-free?  Go to subscribetojj.com Enjoy the VIP experience for just $4.99/month or $49.99/year (save 17%!) Click “TRY FREE” and start your ad-free journey today!   Full show notes (including all links mentioned): https://jjvirgin.com/dylan

A $250K grant intended to install LGBTQ+ historical markers in Ohio was abruptly canceled by the Department of Government Efficiency (DOGE), sparking backlash from advocacy groups and lawmakers. The panel examines why commemorating LGBTQ+ history is being politicized and what this says about state-level efforts to erase marginalized voices from public memory.News Source: Central Ohio News by David Rees, April 8, 2025https://www.nbc4i.com/news/local-news/central-ohio-news/doge-cancels-250000-ohio-grant-installing-lgbtq-historical-markers/The Non-Prophets 24.16.2 with Scott Dickie, Jonathan Roudabush and Eli SlackDOGE Withdraws $250K from LGBTQ+ History Project

Send us a textExploring Laughlin Ranch's exceptional desert golf layout tops our agenda this week, as Jeremy and Dan experience this hidden gem for the first time. The course earns unanimous praise from our crew for its strategic design, challenging greens, and memorable finishing stretch. "It's scorable, but it's also a thin line between being scorable and also will whip your ass," Jeremy observes, highlighting the course's perfect balance of accessibility and challenge.The confusing tee markers spark a heated debate, with Joe frustrated by the identical mining-cart-wheel markers that lack clear color differentiation. "I just wish there was a zinc plating on those T-markers, or a gold plating or a copper plating, because they all look the same," he argues, while others defend the unique mining-themed design. Despite this minor complaint, all agree Laughlin Ranch belongs in their personal top-10 rankings.We dive into golf equipment reselling on Whatnot, with Joe and Matt sharing both success stories and warnings about potential scams. "If you're not educated, you can fall for that easily," Matt cautions, offering tips for scoring legitimate deals on the increasingly popular platform. The conversation shifts to Justin Thomas's impressive 61 at Harbortown, with Jeremy providing perspective from having played the notoriously tight course himself. We also recap the recent TopGolf Invitational, where Dan's enthusiastic participation in the alcohol offerings led to some memorable singing across Horizon Ridge. The episode wraps with birthday dinner recommendations for Matt, with Cleaver emerging as the unanimous steakhouse choice.Subscribe to our YouTube channel and help us reach our 500-subscriber milestone—we've got gift cards waiting to celebrate with our loyal listeners!The Las Vegas Golf SuperstoreThe premier retail destination for golfers in the Las Vegas Valley!The Golf StopAn indoor Trackman Lounge in the south end of the valley featuring four bays, a snack bar, and beer!Rohrs Golf Fitting & building tips, tricks, swag, and custom creations from Neal Rohrbach.Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.We hope you enjoy this week's episode, and if you do, please consider leaving us a review on either Spotify or iTunes. Thank You!

Struggling with mystery symptoms? Most people chalk up brain fog, fatigue, or joint pain to aging, but what if it's your body screaming for help? I sat down with Dr. Will Cole to discuss autoimmune conditions, gut health, and toxicity. Here's the truth: your symptoms might stem from hidden culprits like mold, heavy metals, or a stressed-out gut. Cleaning up your gut and reducing toxins lets your body do what it's built for… heal! Small, consistent changes can transform your health. Join the Ultimate Human VIP community and gain exclusive access to Gary Brecka's proven wellness protocols today!: https://bit.ly/4ai0Xwg Get Dr. Will Cole's book, “The Inflammation Spectrum”: https://amzn.to/4jnQe7r  Listen to “ Dr. Will Cole “ on all your favorite platforms! YouTube:https://bit.ly/4jmEv9c  Spotify:https://spoti.fi/4jCWkB7  Apple Podcasts: https://apple.co/4lzYenb Connect with Dr. Will Cole: Website:https://bit.ly/4iurxF0  YouTube: https://bit.ly/4jmEv9c  Instagram:https://bit.ly/3GlSihK Facebook:https://bit.ly/4lGTEUh TikTok:https://bit.ly/4444EVw X.com: https://bit.ly/4cI59qw LinkedIn:https://bit.ly/4jEMG02 Thank you to our partners: H2TABS - USE CODE “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg BODYHEALTH - USE CODE “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV BAJA GOLD - USE CODE "ULTIMATE10" FOR 10% OFF: https://bit.ly/3WSBqUa EIGHT SLEEP - SAVE $350 ON THE POD 4 ULTRA WITH CODE “GARY”: https://bit.ly/3WkLd6E COLD LIFE - THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp WHOOP - GET 1 FREE MONTH WHEN YOU JOIN!: https://bit.ly/3VQ0nzW MASA CHIPS - GET 20% OFF YOUR FIRST $50+ ORDER: https://bit.ly/40LVY4y VANDY - USE CODE “ULTIMATE20” FOR 20% OFF: https://bit.ly/49Qr7WE AION - USE CODE “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD HAPBEE - FEEL BETTER & PERFORM AT YOUR BEST: https://bit.ly/4a6glfo CARAWAY - USE CODE “ULTIMATE” FOR 10% OFF: https://bit.ly/3Q1VmkC HEALF - GET 10% OFF YOUR ORDER: https://bit.ly/41HJg6S BIOPTIMIZERS - USE CODE “ULTIMATE” FOR 10% OFF: https://bit.ly/4inFfd7 RHO NUTRITION - USE CODE “ULTIMATE15” FOR 15% OFF: https://bit.ly/44fFza0 Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka: Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X.com: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps: 00:00 Intro 01:45 Definitions of Metabolic Health and Flexibility  13:23 Markers for Metabolic Inflammation Spectrum 17:16 Being Metabolically Healthy by Making Healthy Lifestyle Choices 19:50 Potential Impacts of the MAHA Movement 21:32 Toxic Burden Impacting Autoimmune Conditions 26:56 Leaky Gut Syndrome 29:56 Testing to Identify One's Conditions 33:49 Emotional Connection with the Gut 41:23 Implementing Lifestyle Habits to Address Stress & Trauma 45:27 Gratitude and Self-Compassion 52:43 Testing for Mold Toxicity 58:15 Role of Genetics  59:04 Practices to Improve Gut Health 1:03:01 Fasting as a Hormetic Therapy 1:06:20 Testing for Metal Toxicity and Resolutions 1:12:29 Daily Habits Causing Inflammation The Ultimate Human with Gary Brecka Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The Content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Lindsay Gibson joins Forrest to explore emotional immaturity, the consequences of growing up with emotionally immature caregivers, and what we can do to change those patterns in adulthood. They discuss the key signs of emotional immaturity, including egocentrism, low empathy, and affective realism. Dr. Gibson then shares how having an emotionally immature parent affects children, often by leading to emotional disconnection and people-pleasing, and the consequences of these patterns in adult life. Topics include the problems with “just be more compassionate,” estrangement, balancing competing desires, and how to heal in adulthood by reconnecting with your feelings, letting go of old fantasies, and setting healthy boundaries. About our Guest: Dr. Lindsay Gibson is a clinical psychologist and the author of the Emotional Immaturity series of books, including her bestseller Adult Children of Emotionally Immature Parents.  You can watch this episode on YouTube. Key Topics: 0:00: Introduction 1:15: How Dr. Gibson defines emotional immaturity 6:45: Markers of emotional immaturity in parents 11:05: Emotional intelligence in children, loneliness, and regulating parents 19:05: The arc of recovery, responding to feelings with thoughts, and healthy guidance 31:00: Repeating patterns in relationships 36:15: Letting go of the healing fantasy, and when to take space 42:45: Estrangement, compassion, boundary setting, and becoming more authentic 58:45: When healthy change creates social pressure 1:01:55: Common misconceptions about emotional immaturity 1:06:05: Recap Support the Podcast: We're now on Patreon! If you'd like to support the podcast, follow this link. Sponsors Head to fastgrowingtrees.com/BEINGWELL to get 15% off the best deals for your yard. Use BEINGWELL at checkout, and take advantage of their Alive and Thrive Guarantee! Sign up for a one-dollar-per-month trial period at shopify.com/beingwell.  Go to ZOE.com and find out what ZOE Membership could do for you. Use code WELL10 to get 10% off membership. Get 15% off OneSkin with the code BEINGWELL at https://www.oneskin.co/  Connect with the show: Subscribe on iTunes Follow Forrest on YouTube Follow us on Instagram Follow Forrest on Instagram Follow Rick on Facebook Follow Forrest on Facebook Visit Forrest's website Learn more about your ad choices. Visit megaphone.fm/adchoices

Jake and Tony are back looking at the 4th marker of Lead222's 9 Markers of a Healthy Youth Ministry, Tenacious Teaching. Take a listen as they talk about the importance of teaching with purpose, what the win of teaching should look like and the fact that Tony survived a tornado by attending a concert. Enjoy!Bo Challenge: Come up with the 5 Ministry Values that you want to have in your Student Ministry! You will be able to teach with purpose knowing what you are wanting to see as values in your Student Ministry. FOLLOW US ON INSTAGRAM: @lead.222-------Did this conversation resonate with you? Do you have a suggestion for a future episode? We want to hear from you! Write us at info@lead222.com Help us grow the community!Subscribe, share, and leave a review.For more information about Lead222 or find a community of leaders in your area: ⁠⁠⁠www.lead222.com ⁠⁠⁠Lead222 Youth Ministry Staffingwww.Lead222/⁠⁠⁠staffing.com⁠⁠⁠

This week, Tam slows down with something simple: coloring with markers. She shares how this childhood favorite helped her through a rough patch and turned into a sweet act of care for herself that she could share with others. From messy lines to quiet joy, it's a cozy reminder that creativity doesn't have to be perfect to be healing. @theartofhobbyness www.artofhobbyness.com

This week, two partial Poles make fun of the Polish people as we tell the legendary story of Stefan Michalak.   Merch: https://www.etsy.com/shop/cryptopediamerch Discord: https://discord.gg/AWpen8aYQG Patreon: https://www.patreon.com/user?u=14015340 YouTube (Videos have [questionable] captions!): http://youtube.cryptopediacast   --- Falcon Lake incident is Canada's 'best-documented UFO case,' even 50 years later - CBC Population of Canada by province and territory - Wikipedia Unsolved Mysteries with Robert Stack - Season 5, Episode 8 - Full Episode Find a Grave - Stefan Michalak When They Appeared: Falcon Lake 1967: The inside story of a close encounter Under the cloud : the decades of nuclear testing : Miller, Richard L. (Richard Lee),  Stefan Michalak, Falcon Beach, Manitoba- Police Report - 26 May 1967  Gastrointestinal Acute Radiation Syndrome: Mechanisms, Models, Markers, and Medical Countermeasures - PMC The Winnipeg Tribune - 22 May 1967 - Police Report - 18 June 1967  - Police Report - 10 August 1967  The Iron Skeptic - Stefan Michalak

How can you stay motivated? Let's come up with ideas together!Text me at 972-426-2640 so we can stay connected!Support me on Patreon!Twitter:  @elliottspeaksInstagram: @elliottspeaks Text me at 972-426-2640 so we can stay connected!Support me on Patreon!Twitter: @elliottspeaksInstagram: @elliottspeaks

In this fascinating episode of the RWS Clinician's Corner, we do a deep dive into all things blood sugar with diabetes expert, Dr. Beverly Yates. We discuss how proper blood sugar handling is one of the body's topmost priorities, and how dysregulated blood sugar levels have far-reaching implications on the body and mind. Her commitment to advancing knowledge in the field underscores her passion for addressing complex health challenges and delivering impactful results for her clients.   In this interview, we explore:    -The paramount importance of blood sugar regulation in preventing all manner of chronic disease   -A closer look at Advanced Glycation End-products (AGEs)   -The significance of advanced lab markers in nutrition practice - what markers most practitioners miss and how to use the information gleaned from these to get even better results with your clients    -Practical strategies to enroll your clients in the lifestyle/behavior changes that are so essential to this process    Connect with Dr. Yates: Website: https://naturalhealthcare.com Instagram:  https://instagram.com/drbeverlyyates    YouTube Channel: https://www.youtube.com/c/DrBeverlyYates   Facebook: https://www.facebook.com/drbeverlyyates/   LinkedIn: https://www.linkedin.com/in/womenshealthexpert/    Timestamps: 00:00 Dr. Yates: Diabetes Program Innovator 09:45 Reconnecting with Estranged Father 11:31 "Clinicians Corner: Transformative Health Training" 19:32 Diet Challenges in Silicon Valley 23:14 "Personalizing Diet with CGM" 28:01 Intermittent Fasting & Carb Dependency 33:01 Blood Sugar Crashes and AGEs 41:39 Monitoring Metabolic Health Insights 45:30 Appetite Hormones and GLP1 Benefits 51:33 Genetic Discovery in Heart Health 58:00 Why Mimic Meat in Vegan Diets? 01:00:24 CGMs Reveal Oatmeal Intolerance 01:05:13 "Clinician's Corner: Episode Highlights"   Speaker bio:    Dr. Beverly Yates ND, is a licensed Doctor of Naturopathic Medicine. She is the nation's leader in online type 2 diabetes care – and she is on a mission to help 3 million people heal from type 2 diabetes and prediabetes. She used her background in MIT Electrical Engineering and work as a Systems Engineer in Silicon Valley to create effective online programs for people with diabetes to achieve blood sugar control and live the life they love.   Dr. Yates is an internationally recognized speaker and expert in diabetes and heart disease. She is a published author of Heart Health for Black Women: A Natural Approach to Healing and Preventing Heart Disease, and co-author of multiple books, including with Jack Canfield, The Soul of Success, Vol. 2. She is writing a new book on type 2 diabetes and prediabetes, based on her Yates Protocol, focusing on 5 Practical, Enjoyable Steps to Reversing Type 2 and Prediabetes and Living the Life You Love. Dr. Yates has been featured in numerous media outlets, including ABC, CBS, NBC, PBS, NPR, Black News Channel, Fox, Sirius XM, MindBodyGreen, Essence Magazine, Good Housekeeping, Women's World, Readers Digest, Rodale Press, and more. Keywords:   Restorative Wellness, Blood Sugar, Type 2 Diabetes, Pre Diabetes, CGM (Continuous Glucose Monitor), Nutrition, Meal Timing, Stress Management, Sleep Quality, Exercise, Glycemic Control, Advanced Glycation End Products (AGEs), Fasting, Insulin Sensitivity, Metabolic Health, Heart Disease, Cognitive Impairment, Plant-based Diet, Supplements, D Ribose, Resveratrol, Ubiquinol, Hemoglobin A1C, Fasting Insulin, C Peptide, Fructosamine, Leptin, Vegetarian Diet, Vegan Diet, Chronic Illness   Disclaimer: The views expressed in the RWS Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of Restorative Wellness Solutions, LLC. Restorative Wellness Solutions, LLC does not specifically endorse or approve of any of the information or opinions expressed in the RWS Clinician's Corner series. The information and opinions expressed in the RWS Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. Restorative Wellness Solutions, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the RWS Clinician's Corner series. By viewing or listening to this information, you agree to hold Restorative Wellness Solutions, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.  

In this episode, Ed Frawley shares a question from the Ask Cindy database. Today's question is about a 5-year-old pointer who is a light chaser. The breeder chose to use a laser light to tire the puppies out, leading this dog to become obsessed with light reflections and shadows. Ed addresses the issue and offers advice on how to manage this problem. | Links mentioned: How We Manage Dogs in Our Home: https://university.leerburg.com/Catalog/viewCourse/cid/14 | The Power of Training Dogs with Markers (2024): https://leerburg.com/marker-dvd.php | Remote Collar Training for the Pet Owner with Ed Frawley: https://leerburg.com/ecollar-pet-owner.php | Bernhard Flinks Protection Seminar: https://university.leerburg.com/Catalog/viewCourse/cid/239

John Starke preaches from Acts 11:1-18, continuing our sermon series "Acts: Becoming the New".

Grab the Goss-X cause this goss is bubbling up! Alaska and Willam chat about trips to Brazil, political contingency plans, and the 25th anniversary of ‘Aida.' Plus ‘White Lotus' tea, Bob's new book, and WeHo Pride performers. Got Goss? Listen to Race Chaser Ad-Free on MOM Plus Follow us on IG at @racechaserpod and click the link in bio for a list of organizations you can donate to in support of Black Lives Matter Rainbow Spotlight: Trust by Rebecca Black FOLLOW ALASKA https://twitter.com/Alaska5000 https://www.instagram.com/theonlyalaska5000 https://www.facebook.com/AlaskaThunder https://www.youtube.com/channel/UC9vnKqhNky1BcWqXbDs0NAQ FOLLOW WILLAM https://twitter.com/willam https://www.instagram.com/willam https://www.facebook.com/willam https://www.youtube.com/channel/UCrO9hj5VqGJufBlVJy-8D1g RACE CHASER IS A FOREVER DOG PODCAST Learn more about your ad choices. Visit megaphone.fm/adchoices

"The truth will set you free... and Knuckles." The season two finale of Markers on the Map is a celebration of some of the finest games to ever be released. But first, the biggest ever lore cutscene reveals just what happened on all of those fateful days, tying up loose ends, and finally bringing us to a brave new era. Twists, turns, and revelations abound as we head into the unknown. And then, we kick off this milestone episode with some reminiscing and some Monster Hunter Wilds. And in true season finale fashion, we discuss a couple of secret games, some of our absolute favorites. Full spoilers, full specials, and some of our most in-depth commentary on these two absolute classics are here in this legendary episode. A new season is coming, and you can always keep up with the show on BlueSky @MarkersOnTheMap.

Feeling Like Success Has to Equal Exhaustion? Discover How to Scale Your Business Without Sacrificing What Matters Most If you've ever felt like quitting your business, you're not alone! In this episode, I sit down with author and host of the What Works podcast, Tara McMullin, to explore how to create a business that truly supports the life you want. Tara has been challenging conventional business wisdom for over 16 years and brings a refreshing approach to success, productivity, and growth. She explains why focusing solely on revenue goals can lead to burnout, how to honor your actual capacity, and the importance of defining success on your own terms. We dive into why saying "no" might be your most powerful business strategy, how to escape the validation spiral that keeps you overcommitted, and the transformative difference between being "busy" and being "squeezed." HERE ARE THE 3 KEY TAKEAWAYS FROM THIS EPISODE: 1️⃣ Your Business Should Support Your Life – Start with your personal variables and non-negotiables first. Your business is a needs-meeting machine, and your needs as the business owner must come first. 2️⃣ Honor Your Capacity – We all have different capacities based on our available resources—time, money, emotional bandwidth, support networks, and skills. Before taking on new projects, ask: "Do I have what I need to do this well?" 3️⃣ Escape the Validation Spiral – Be cautious about constantly adding new commitments to feel valuable. This leads to depleted resources, underdelivering, and a spiral of taking on even more to compensate. RESOURCES MENTIONED IN THIS EPISODE: Subscribe to What Works: Apple Podcasts and Spotify  Learn more about Yellow House Media: yellowhouse.media  Connect with Tara: whatworks.fyi  Read the Wall Street Journal article Tara shared: The Delusion of 'Profits' By Peter F. Drucker MORE FROM ME Follow me on Instagram @amyporterfield SUBSCRIBE & REVIEW If you loved this episode, please take a moment to subscribe and leave a review on Apple Podcasts! Your support helps us reach more entrepreneurs who need these insights.

Title: Confidence Markers: Anointing, Abiding, AppearingText: 1 John 2:26-3:33Chris HefnerConfidence MarkersMarker 1: Anointing—Because we've been anointed by God, we are his children.Marker 2: Abiding—Since we are God's children, we must abide in him.Marker 3: Appearing—Because Jesus will appear, and we will be like him then, we must pursue purity now.Please reach out to us with any questions info@wilkesborobaptist.org

In this episode, Dr. Valentin Fuster discusses a groundbreaking study on the link between cigarette smoking and subclinical cardiovascular harm, focusing on markers of inflammation, thrombosis, and atherosclerosis. The research, based on data from over 182,000 participants across 22 cohorts, reveals how smoking intensity and duration impact early cardiovascular damage and highlights the potential of these biomarkers in shaping future public health strategies and regulatory policies.

Jake and Tony are back again looking at the 9 Markers of a Healthy Youth Ministry! This week is part 2 of their discussion on Student Ownership. They had the chance to chat with Lead222's own Toby Thomack and a Youth Leader of his, Kiara, about how this marker is key to their ministry! Grab a cup of coffee, steam some tea, and take a listen as they discuss Kiara's student ownership journey, Toby's student intern program, and Tony's inability to eat an ice cream bar properly. Enjoy! Bo Challenge: Pray that students would have a heart to own the ministry they are a part of! If you already have student ownership happening, pray for them to continue growing in faith and their relationship with God!

In this episode, Ed Frawley shares a question from the Ask Cindy database. Today's question is about a service dog in training that has started to react poorly to some dogs in public. The handler is asking what they can do to modify this behavior before it becomes a bigger problem.| Links mentioned: The Power of Training Dogs with Markers (2024) - https://leerburg.com/marker-dvd.php | Training Dogs with Food Rewards - https://leerburg.com/food-dvd.php | Leash Skills - https://leerburg.com/LeashSkillswithEllisDVD.htm | Leash Reactivity with Tyler Muto - https://leerburg.com/leashreactivitydvd.php

Are adaptogens truly powerful, or are they just another wellness trend? In this episode of Super Life, Darin Olien dives deep into the science and history of adaptogens, breaking down what they really do for the body. From his decades of superfood hunting, Darin shares firsthand experiences discovering powerful botanicals like ashwagandha, Rhodiola, maca, and Schisandra, and how these ancient remedies are finally being recognized by modern science. He also uncovers the hidden truth about supplement quality, the best adaptogens for stress relief, and why some companies are misleading consumers with under-dosed, ineffective products. If you want to reduce stress, boost energy, and understand the REAL benefits of adaptogens, this episode is a must-listen. What Are Adaptogens? Definition: Adaptogens are compounds that enhance the body's resilience to stress and promote recovery by normalizing physiological processes, boosting energy and endurance, and protecting against cellular damage. Used in Ayurveda, Traditional Chinese Medicine, and Indigenous Healing Practices for centuries. Modern science is now validating—or challenging—these ancient uses. Scientific Evidence on Adaptogens for Stress Relief Comprehensive Benefits of Adaptogens A 2023 review confirmed the effectiveness of adaptogens in managing conditions linked to chronic stress, including anxiety, depression, fatigue, and cognitive disorders. The study highlighted commonly used adaptogens such as Rhodiola Rosea, Panax Ginseng, Eleuthero, and Ashwagandha as having significant therapeutic potential (Altanova & Korolyova, 2023).   Human Trials Show Adaptogens Can Reduce Stress A randomized, placebo-controlled trial found that adaptogenic supplements significantly improved stress resilience in 215 elite athletes. Markers such as cortisol levels, fatigue severity, and cognitive function showed measurable improvements (Hovhannisyan et al., 2017).   The Mechanism Behind Adaptogens' Effect on Stress Adaptogens regulate stress response pathways, particularly the hypothalamic-pituitary-adrenal (HPA) axis, controlling cortisol levels and stress markers like nitric oxide. This means they help maintain homeostasis and protect against both acute and chronic stress (Pawar & Shivakumar, 2012).   Effectiveness in Mental and Behavioral Disorders A systematic review on adaptogens found that Rhodiola Rosea, Eleutherococcus Senticosus, and Schisandra Chinensis all had documented effects on stress-related disorders, particularly by modulating neuroendocrine function (Panossian, 2013).   Ashwagandha and Rhodiola Specifically Target Stress and Fatigue A 2017 study reviewed the effects of Ashwagandha, Rhodiola, and Bacopa on cortisol levels and fatigue. The study concluded that these herbs significantly reduced stress-related fatigue and improved cognitive function (Ajala, 2017).   Potential Industry Bias in Adaptogen Research Some studies point out that while adaptogens have shown promise in treating stress and aging-related diseases, there is still limited large-scale human clinical data, and more rigorous studies are needed. The variability in adaptogen potency due to genetic and environmental factors complicates assessments of their true effectiveness (Panossian et al., 2020). Additionally, some adaptogen formulations are standardized by supplement companies, which raises concerns about industry influence on the research outcomes. Most Shocking Findings Adaptogens Can Mimic Stress to Build Resilience: They act as mild stress mimetics, triggering the body's adaptive stress response in small doses, similar to how a vaccine stimulates the immune system (Panossian et al., 2020). Cortisol Regulation is Key: Studies show adaptogens normalize elevated cortisol levels, preventing burnout and cognitive decline (Ajala, 2017). Elite Athletes Showed Significant Gains: Athletes taking adaptogens had a measurable improvement in reaction time, stress tolerance, and performance, suggesting real physiological benefits (Hovhannisyan et al., 2017).     Key Adaptogenic Herbs & Their Scientific Evidence 1. Ashwagandha (Withania somnifera) Study: “A Review on Adaptogenic Activity of Ashwagandha (Withania Somnifera): An Ayurvedic Appraisal” Dosage Used in Studies: 300-600 mg/day Key Findings: Ashwagandha significantly reduces cortisol levels, enhances stress resilience, and improves cognitive function (Shrilata et al., 2017). Direct Quote from Study: "Ashwagandha has been shown to significantly reduce stress-related cortisol levels and improve anxiety symptoms in clinical trials." 2. Rhodiola Rosea Study: “The Effects of Adaptogens on the Physical and Psychological Symptoms of Chronic Stress” Dosage Used in Studies: 200-600 mg/day Key Findings: Rhodiola improves mental clarity, reduces fatigue, and stabilizes stress-induced hormonal changes (Ajala, 2017). Direct Quote from Study: "Rhodiola Rosea has demonstrated significant anti-fatigue and anti-stress properties, improving cognitive function and resilience in individuals exposed to chronic stress." 3. Schisandra Chinensis Study: “Adaptogens in Mental and Behavioral Disorders” Dosage Used in Studies: 500-1500 mg/day Key Findings: Schisandra enhances adrenal function, improves focus, and has neuroprotective effects(Panossian, 2013). Direct Quote from Study: "Schisandra has adaptogenic effects that enhance cognitive performance, improve stress resilience, and protect the nervous system from oxidative stress." 4. Maca Root (Lepidium meyenii) Study: “Effects of Adaptogens on the Central Nervous System” Dosage Used in Studies: 1500-3000 mg/day Key Findings: Maca supports energy levels, hormonal balance, and mood stability (Panossian & Wikman, 2010). Direct Quote from Study: "Maca root exhibits adaptogenic activity, particularly in enhancing physical stamina and resilience against psychological stress."     Shocking Research Insights Adaptogens Mimic Stress to Build Resilience Some researchers describe adaptogens as “mild stress mimetics”, triggering small stress responses that strengthen the body's ability to handle major stressors (Panossian et al., 2020). Clinical Trials on Elite Athletes Prove Effectiveness A randomized controlled trial on 215 elite athletes found that adaptogens significantly improved stress tolerance, reduced cortisol, and enhanced reaction time (Hovhannisyan et al., 2017). Industry Bias: Are Adaptogens Overhyped? Some studies highlight a lack of large-scale, independent research and potential conflicts of interest in studies funded by supplement companies (Panossian et al., 2020). Final Thoughts: Science or Pseudoscience? Science-Backed Benefits Exist: Studies show adaptogens modulate stress response systems, reduce fatigue, and improve mental performance. More Human Trials Needed: Many studies rely on animal models or small-scale trials. The lack of large-scale, independent clinical trials leaves some uncertainty. Potential Industry Bias: While there is strong evidence for adaptogens, commercial interests may be influencing research directions and outcomes.     What You'll Learn in This Episode: (00:00:00) Introduction – The growing hype around adaptogens: real or marketing? (00:02:15) The Power of Plants & Adaptogenic Herbs – Why ancient cultures relied on them for thousands of years. (00:04:19) Are Adaptogens Actually Stress Relievers? – What the research says about their effects. (00:06:21) How Stress Affects the Body – The connection between modern lifestyle and chronic stress. (00:07:05) The Science of Adaptogens & Stress Response – How they regulate the nervous system. (00:09:09) The Best Research-Backed Adaptogens – Ashwagandha, Rhodiola, ginseng, and more. (00:11:32) Why Your Supplement Might Be Useless – The industry's biggest problem: poor quality. (00:13:45) Adaptogens & Athletic Performance – What studies show about energy, stamina, and recovery. (00:16:20) The Problem with Western Medicine Ignoring Adaptogens – Why ancient wisdom is finally being validated. (00:19:18) The Best Way to Take Adaptogens – Should you use tinctures, powders, or capsules? (00:21:10) How to Find High-Quality Adaptogens – What to look for in supplement brands. (00:23:40) Final Thoughts & How to Use Adaptogens Daily – The best way to integrate them into your routine.     Thank You to Our Sponsors: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout.     Find More From Darin: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences     Key Takeaway: "Adaptogens aren't a quick fix—but used correctly, they can be one of the most powerful tools for long-term resilience, energy, and stress management."     Bibliography: Altanova & Korolyova, 2023 – Review on adaptogens in stress-induced conditions. Hovhannisyan et al., 2017 – Adaptogens improve athletic performance and stress tolerance. Ajala, 2017 – Effects of Ashwagandha, Rhodiola, and Bacopa on stress markers. Panossian, 2013 – Adaptogens for mental health. Panossian & Wikman, 2010 – Neurological effects of adaptogens.

A 2023 study that we looked at has some very interesting results and implications on cholesterol and longevity I wanted to share in today's episode. We'll look at the study details, why this is important, what it means for you, and more. Topics include: - High Cholesterol A Top Longevity Marker?- What We'll Cover- Why This is Important- Geriatric Journal Study- Similar Episodes In The Feed- Breaking Down the Study- Looking At The Data and My Coaching Experience---------- ⁠My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization ⁠⁠www.metabolismschool.com⁠---------- [Free] Metabolism School 101: The Video Series⁠http://www.metabolismschool.com/metabolism-101⁠----------Subscribe to My Youtube Channel: ⁠https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1⁠----------⁠Grab a Copy of My New Book - Metabolism Made Simple⁠---------- Stay Connected: ⁠Instagram: @sammillerscience⁠ ⁠Youtube: SamMillerScience⁠ ⁠Facebook: The Nutrition Coaching Collaborative Community⁠ ⁠TikTok: @sammillerscience⁠  ----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at ⁠operations⁠⁠@sammillerscience.com⁠. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."

In this episode, Ed Frawley shares a question from the Ask Cindy database. Today's question is about a 13-week-old german shepherd puppy that is suddenly a bit reluctant to go on walks as the puppy is starting to experience a fear period as it is growing up and developing. | Links mentioned: Raising Your Puppy: https://leerburg.com/ellispuppydvd.htm | Your Puppy 8 Weeks to 12 Months: https://leerburg.com/120.htm | Power of Training Dogs with Markers: https://leerburg.com/marker-dvd.php | Training Dogs with Food Rewards: https://leerburg.com/food-dvd.php | The Power of Training Dogs with Food: https://leerburg.com/training-with-food.htm | The Power of Playing Tug with Your Dog: https://leerburg.com/221.htm

I think the whole episode is more interesting than just the Main Points! Here are the 5 Tips for Moving Forward with the Mission, 5 Markers of the Inferior Man, and everything else in between.Thank you for your support!Let's Work Together: Interest Form Website: https://www.iamtaylorchandler.com/Instagram: @iamtaylorchandler YouTube: @iamtaylorchandler

  In this milestone 100th episode, dive into essential resume and LinkedIn advice, including the importance of a LinkedIn profile, common resume mistakes to avoid, and actionable tips to make your resume stand out to recruiters and hiring managers. Learn how to replace vague adjectives and adverbs by emphasizing specific accomplishments, tailor your resume for your target role, and more.   We'll Talk About: 02:14 Three Important Principles 03:58 Tip 1: Remove Adjectives and Adverbs 09:00 Tip 2: Swap Vague Phrases for Specifics 10:12 Tip 3: Use Raw Numbers Over Percentages 12:09 Tip 4: Avoid Wordy Bullets 14:32 Tip 5: Focus on Relevant Career History 17:03 Tip 6: Ensure Breathing Room in Your Resume 19:17 Tip 7: Prioritize Content Over Template 26:29 Tip 8: Avoiding Commoditized Language 28:59 Tip 9: Starting with Your Target Role 32:35 Tip 10: The Importance of a Strong LinkedIn Profile _________________________________________________________________ Connect with Me Connect with me on LinkedIn From Zero Responses to Multiple Offers: Download The 5 Essential Steps Checklist Click here to learn about coaching Referenced Materials: Book your Diagnostic and Power Strategy Hour Listen to Episode 2: Swap These Three Time-Wasting tasks to Accelerate Your Career Search 

Heart disease has been the leading cause of death in the U.S. for over a century—despite massive healthcare spending and widespread use of cholesterol-lowering drugs. So why aren't we seeing better outcomes? In this episode, we're breaking down the true drivers of heart disease and why cholesterol alone doesn't tell the whole story. We'll explore the key cardiovascular markers that actually matter, from inflammation and metabolic dysfunction to oxidative stress and insulin resistance. Tune in as we dive into what your doctor might be missing, how to assess your real heart disease risk, and the diet, lifestyle, and supplement strategies that can help protect your heart. Learn why inflammation—not just cholesterol—is at the root of cardiovascular disease, and how food-as-medicine can be a powerful tool for prevention. Whether you have a family history of heart disease or just want to optimize your health, this episode is packed with essential insights! Also in this episode:  Sign up for a FREE Heart Health Webinar 2/28 Get $100 off the Cardiometabolic Panel with code CARDIO100 Episode 40 Heart Health and Cholesterol Episode 157 Cholesterol as Medicine Episode 128 Keto Cardiologist with Guest Episode 283: Heart Health Updates Episode 284: Navigating the Cardiometabolic Panel  Episode 365: Lipoprotein a Episode 331: Homocysteine  Episode 333: Understanding the Heart with Dr Stephen Hussey Trends of Cardiovascular Disease Statin Prescription Trends What markers are included in standard heart disease screening?  Why are these markers not enough? What inflammation and metabolic health are the real risk factors The impact of perimenopause on lipids Lab markers that matter LDL Particle Count & Distribution Northwest Wild Foods use code ALIMILLERRD for savings Mediterranean Tuna Salad EPA DHA Extra 2 twice daily Or EPA DHA Liquid 2-3 tsp daily How to Eat More Fish PhytoFiber Low HDL Multidefense B Complex Lipoprotein a Berberine Boost Phytofiber COQ10 Complex (essential if you are on a statin!) Inflammazyme Hs-CRP Super Turmeric Inflammazyme EPA DHA Extra MRT Inflammatory Food Panel Homocysteine MethylComplete Fasting Insulin Berberine Boost Apo A Apo B Heart Health Bundle    Sponsors for this episode:  This episode is sponsored by Wild Foods, a company that puts quality, sustainability, and health first in all of their products. They have everything from coffee to turmeric to medicinal mushrooms, and every single product is painstakingly sourced from small farms around the globe. They take their mission seriously to fix the broken food system, and believe real food is medicine. They've partnered with us to give you guys an exclusive discount, so use the code ALIMILLERRD for 12% off your order at WildFoods.co! 

This season is about making clear distinctions between who is who. Who can progress forward with us and who is going in a different direction.Here are 5 Markers of the Inferior ManThank you for your support!1-on-1: Interest FormCashapp: $taychand Website: https://www.iamtaylorchandler.com/Instagram: @iamtaylorchandler YouTube: @iamtaylorchandler

NFL technology needs an update; Another close play in the Bills-Chiefs game results in a discussion of human error with a potential first down; Vikings running game should take notes from the Eagles; Who should we be rooting for in this year's Super Bowl; Plus statements on the Twins SS Carlos Correa and more on weekend statements and questions. Learn more about your ad choices. Visit podcastchoices.com/adchoicesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.