POPULARITY
In this episode, Gregory J. Tiesi, MD, FACS, FSSO, hosted a discussion about the growing role for transarterial microperfusion (TAMP) as a regional therapy strategy for patients with locally advanced pancreatic ductal adenocarcinoma (PDAC). Dr Tiesi is the medical director of Hepatobiliary Surgery at the Hackensack Meridian Jersey Shore University Medical Center in Neptune, New Jersey. He was joined by: Anthony Scholer, MD, FACS, FSSO, a surgical oncologist specializing in hepatobiliary surgery at Hackensack Meridian Medical Group and Jersey Shore University Medical Center in Neptune, New Jersey Eric Pletcher, MD, a surgeon specializing in Complex General Surgical Oncology at Hackensack Meridian JFK University Medical Center in Edison, New Jersey PDAC is a disease in which dense desmoplastic stroma and poor tumor vascularization often limit the effectiveness of standard systemic chemotherapy. Drs Tiesi, Scholer, and Pletcher explained that standard regimens, such as FOLFIRINOX or gemcitabine-based combinations, frequently fail to achieve adequate intratumoral drug concentrations because of these biologic barriers. TAMP aims to overcome this limitation by isolating a segment of an arterial vessel and pressure-mediated transvascular delivery, which would allow for higher local drug concentrations and reduce systemic exposure and toxicity. The experts noted that TAMP is currently being explored primarily in patients with locally advanced, unresectable pancreatic cancer without distant metastases, particularly those who have exhausted systemic treatment options but maintain localized disease. Early clinical studies, including the phase 1/2 RR1 trial (NCT02237157) and the observational RR2 dose-escalation study (NCT02591082), demonstrated that the procedure is technically feasible, repeatable, and associated with lower systemic toxicity compared with conventional chemotherapy. A pooled analysis of these studies suggested encouraging survival outcomes, particularly in patients who received prior chemoradiation, potentially because radiation modifies the tumor microenvironment and improves drug penetration. Lastly, Tiesi, Scholer and Pletcher reviewed the ongoing phase 3 TIGeR-PaC trial (NCT03257033), which is evaluating TAMP as a consolidation strategy after induction chemotherapy and radiation. Preliminary data suggest improved survival and substantially fewer serious adverse effects with TAMP vs continued systemic therapy alone. Although the experts cautioned that the approach remains investigational, they agreed that TAMP may provide meaningful local disease control and potentially expand treatment options and preserve quality of life for patients with this aggressive malignancy.
John, Kevin, and Ash discuss WVU's potential hiring of Rich Rodriguez and the beginning of RR2 era football at WVU. What will he need to be successful? John revisits WVU's recent basketball games, and discusses their recent wins. Don't forget to shop at The Book Exchange with our BRAND NEW CODE 4CAST and save 20% off your order with our promo code at checkout. http://bookexchangewv.com!
【節目】【00937B溢價都要買,神奇的魔力?審核機制機制討論,ESG篩選有何好處?】最近這檔債券ETF真的很紅,綜合了會紅的因素,ESG、月月配、收益平準金、低入手價一張1萬5、債券RR2風險等級。看到一些社群的人在瘋狂採買。這集來討論看這檔公司債的特點、優缺點,看看是什麼原因讓大家想搶購? 大綱: 1.00937B溢價都要買 2.現在不買以後更貴 3.溢價會收斂 4.割韭菜 5.Fedwatch 6.持債特性 7.基本資料 8.指數特性 9.指數編製 10.檢視與審核機制 11.標的指數成分券的替換原則 12.產業分佈 13.其他月配息債券、20年期公司債 14.00937B結論,優點缺點 15.S14 EP21 複習 #00937B #群益ESG投等債20+ #公司債 #債券ETF #第344集 節目YouTube 搜尋:威利財經角,Podcast搜尋Awesome_Money。 錄製時間:2023/12/14 #研究僅供參考,請勿做買賣依據,節目非指導教學,投資人應有獨立思考之能力。 威利財經角免費電子報訂閱 https://cutt.ly/lwOV4s2Q 使用電子報原因 https://cutt.ly/kwOV4U8H --- **投資小白貓之旅 **https://vocus.cc/willy03/home 收聽|看文章|互動社群|目錄https://cutt.ly/AwesomeMoney 威利投資生活事Line社群 https://forms.gle/CabjyDhux35utmyU9 提示:動態廣告,內容非威利製播,請謹慎評估 ----以下訊息由 SoundOn 動態廣告贊助商提供---- 台北別墅 三萬坪基地,千米環區林蔭大道,規劃600坪VIP獨立公設會館,58、68、75坪獨棟雙併, 三大套房設計,戶戶擁有私人庭園與頂樓大露台。 接待會館 ➛ 國華高爾夫球場正對面(開車9分即達北投捷運站) 專線 ➛
May the Fourth be with you! Joining us on this special episode is YouTube rock star and all-around great guy Crabbok. We delve into his thoughts on the game and the community and talk a little about RR2's impact on the future of Armada. Are Ackbar Nebulons as OP as everyone thinks? And is seltzer just loud water?Crabbok sings the Horse Song: https://www.youtube.com/watch?v=CTVsiE1cg2EJoin in the podcast discussion on discord at: https://discord.gg/3StPRmsFSt
You remember what we thought was coming in Rapid Reinforcements 2 a couple episodes ago? Yeah, we weren't exactly the closest on that. But hey, RR2 is here, it's exciting, and Fox and Kelorn will take you through their thoughts as we dig deep into every card that's been released. With a little avocado toast on the side. Join in the podcast discussion on discord at: https://discord.gg/3StPRmsFSt
Faaaaaaaala Nerds, Geeks e Freaks!!!!! Chegou mais um NGFCast Live! Das nossas Lives do Youtube, no Canal NGF Sem Limites, mais um podcast direto do Tatame, sem Piedade e sem Compaixão! Kdu o Nerd Mais Velho do Mundo e Adriano Holmes o Índio Nerd do Norte recebem Vanzinha, Felipe e Murilo para falar da quarta Temporada de Cobra Kai!Vamos entender por que o Miguel ta meio "gordim" nessa temporada que nem o Daniel Sam no Terceiro filme, por que o Terry Silver continua sendo o vilão mais anos 80 dos anos 80 e por onde anda Mike Barnes o Bad Boy do Karate!Vem com a gente ouvir esse debate sobre uma das melhores e mais nostalgicas séries dos ultimos anos! E cuidado com os SPOILERS !!! Veja a gravação desse episódio em nosso canal:https://www.youtube.com/watch?v=RR2-fvs74dc_Acompanhe nossas Lives Toda Sexta-Feira, às 22 horas, no nosso Canal do Youtube:https://www.youtube.com/playlist?list=PL3pTJob_CVKaawXlRDPEjZLLujF9sKIsn_Compre os Produtos da Magalu através do nosso Link:https://www.magazinevoce.com.br/magazinengfsemlimites/Escreva pra gente: contatongf@gmail.com ou contato@ngfsemlimites.com.brConheça a Loja Forja Online ( compre com 5% de desconto com o cupom NGF5 )https://forjaonline.com.brSe você começou , está pensando em fazer ou já tem um PODCAST e quer fazer parcerias, entre para a LIGA DOS PODCASTERS !!!!!Edição e Arte na Vitrine: NGF Edições Profissionais de Podcast.Edite seu Podcast Conosco:https://ngfsemlimites.com.br/edicoesprofissionaisdepodcast/Se puder, Fique em Casa
Problems We Solve for Certain Seller Types (LA 1348) Transcript: Steven Butala: Steve and Jill here. Jill DeWit: Hello. Steven Butala: Welcome to the Land Academy Show, entertaining land investment talk. I'm Steven Jack Butala. Jill DeWit: And I'm Jill DeWit, broadcasting from sunny, southern California. Steven Butala: Today. Jill and I are here to talk about the problems we solve for certain seller types. If you've been listening to our show all week, we had an interview, a great interview, with one of our members, [Tiffany Carter 00:00:25]. She shared her why she's successful and we made four or five shows out of it. Real important topics, I got out of the interview. I learned a lot. I learned a lot about her, her success, and I think she speaks for, in a lot of ways, our membership group. Jill DeWit: A lot of people. Mm-hmm (affirmative). I really do- Steven Butala: Yeah. And maybe not just our membership group, but a lot of people who are out there buying and selling land or real estate or whatever. Jill DeWit: Mm-hmm (affirmative). It's true. Steven Butala: Before we get into it though, let's take a question posted by one of our members, on the landinvestors.com online community. It's free. Jill DeWit: Don't worry, I have a lot more to say. I was just saving it for the show. Steven Butala: Oh, I'm not worried. Jill DeWit: Okay. Good. All right. Matthew wrote, "So I got a mailer response last week, and a couple in X County agreed to sell me their four parcels of land... Steven Butala: Awesome. Jill DeWit: ... 15 acres total for $35000. Anticipated sale price is $80000. During due diligence, everything checked out except for the land use. Under land use, one of them is marked down as residential waste." That's kind of funny. "Then further down it says the zoning is RR2- Steven Butala: Rural residential, two acres. Jill DeWit: Mm-hmm (affirmative), minimum lot. And then the others are marked down as land using agricultural livestock raising- Steven Butala: Excellent. Jill DeWit: ... which is also zone RR2. Steven Butala: Excellent. Excellent. Excellent. Jill DeWit: So here's what the county database says." Want me keep going here? Steven Butala: You don't need to read this. Jill DeWit: Okay. "So basically wondering if this type of land is marketable. I spoke with the assessor. She told me basically, when they planned out the subdivision, these were given these designations, because they didn't know what to mark it as. I will send specifics to other members if you're interested. Thanks ahead of time, is really hoping to get this first deal going." Steven Butala: And I actually answered this in Land Investors, which I don't usually do. And here's my answer. Jill DeWit: Okay. Steven Butala: You need to price this deal. There's a lot of money in here. And I really appreciate him giving the economics, buy for 35, sell for 80. You've got to price this transaction as if that residential waste property is going to give you zero. Do I think you're going to sell the residential waste property for probably really some good amount of money? Yeah, I do. I think that it was old civic planning, let's just call it. And unless it's underwater, which you can really tell on Neighbor Scoop, or there a lot of different resources, you can see what's going on. Then I think you're going to be in great shape. The other thing you can do is whatever property it's adjacent to, sell it with it. So you have extra land to do stuff on, but maybe it necessarily can't be built on. The planning and zoning person was very helpful. Jill DeWit: That was really nice, to share that. And I believe that to be true. Steven Butala: Yeah. Jill DeWit: There's all kinds of stuff. Some times that I've talked to the County and everybody's scratching their heads. I'm like, how does that make sense? They're like, yeah, I know I just work here though. I didn't get to pick it. Steven Butala: So I'd go back to the dataset for that County.
Problems We Solve for Certain Seller Types (LA 1348) Transcript: Steven Butala: Steve and Jill here. Jill DeWit: Hello. Steven Butala: Welcome to the Land Academy Show, entertaining land investment talk. I'm Steven Jack Butala. Jill DeWit: And I'm Jill DeWit, broadcasting from sunny, southern California. Steven Butala: Today. Jill and I are here to talk about the problems we solve for certain seller types. If you've been listening to our show all week, we had an interview, a great interview, with one of our members, [Tiffany Carter 00:00:25]. She shared her why she's successful and we made four or five shows out of it. Real important topics, I got out of the interview. I learned a lot. I learned a lot about her, her success, and I think she speaks for, in a lot of ways, our membership group. Jill DeWit: A lot of people. Mm-hmm (affirmative). I really do- Steven Butala: Yeah. And maybe not just our membership group, but a lot of people who are out there buying and selling land or real estate or whatever. Jill DeWit: Mm-hmm (affirmative). It's true. Steven Butala: Before we get into it though, let's take a question posted by one of our members, on the landinvestors.com online community. It's free. Jill DeWit: Don't worry, I have a lot more to say. I was just saving it for the show. Steven Butala: Oh, I'm not worried. Jill DeWit: Okay. Good. All right. Matthew wrote, "So I got a mailer response last week, and a couple in X County agreed to sell me their four parcels of land... Steven Butala: Awesome. Jill DeWit: ... 15 acres total for $35000. Anticipated sale price is $80000. During due diligence, everything checked out except for the land use. Under land use, one of them is marked down as residential waste." That's kind of funny. "Then further down it says the zoning is RR2- Steven Butala: Rural residential, two acres. Jill DeWit: Mm-hmm (affirmative), minimum lot. And then the others are marked down as land using agricultural livestock raising- Steven Butala: Excellent. Jill DeWit: ... which is also zone RR2. Steven Butala: Excellent. Excellent. Excellent. Jill DeWit: So here's what the county database says." Want me keep going here? Steven Butala: You don't need to read this. Jill DeWit: Okay. "So basically wondering if this type of land is marketable. I spoke with the assessor. She told me basically, when they planned out the subdivision, these were given these designations, because they didn't know what to mark it as. I will send specifics to other members if you're interested. Thanks ahead of time, is really hoping to get this first deal going." Steven Butala: And I actually answered this in Land Investors, which I don't usually do. And here's my answer. Jill DeWit: Okay. Steven Butala: You need to price this deal. There's a lot of money in here. And I really appreciate him giving the economics, buy for 35, sell for 80. You've got to price this transaction as if that residential waste property is going to give you zero. Do I think you're going to sell the residential waste property for probably really some good amount of money? Yeah, I do. I think that it was old civic planning, let's just call it. And unless it's underwater, which you can really tell on Neighbor Scoop, or there a lot of different resources, you can see what's going on. Then I think you're going to be in great shape. The other thing you can do is whatever property it's adjacent to, sell it with it. So you have extra land to do stuff on, but maybe it necessarily can't be built on. The planning and zoning person was very helpful. Jill DeWit: That was really nice, to share that. And I believe that to be true. Steven Butala: Yeah. Jill DeWit: There's all kinds of stuff. Some times that I've talked to the County and everybody's scratching their heads. I'm like, how does that make sense? They're like, yeah, I know I just work here though. I didn't get to pick it. Steven Butala: So I'd go back to the dataset for that County.
Every morning on The Big Breakfast, Rachael recommends things to do, they are especially important at the moment! Today she had LOADS of amazing bits to do over the weekend including: Zoo web cams Retro Drive In Movies Isolation Station Catch all the details for them here: [audio mp3="https://media.radiocms.net/uploads/2020/03/20104308/RR2.mp3"][/audio]
Stephen McAlpine is a church planter, blogger and writer from Perth, Western Australia.In this interview with Dave Cornford, Stephen talks particularly about the importance of - understanding context - the liturgy of life as well as the "thick" liturgy of worship - leadershipin church planting.This conversation with a seasoned practitioner is sure to inspire you!Links:Stephen's blog.Desiring the Kingdom - Jamie SmithListen here:Find the podcast on itunes here.
Agradece a este podcast tantas horas de entretenimiento y disfruta de episodios exclusivos como éste. ¡Apóyale en iVoox! La gobernadora Wanda Vázquez Garced detuvo el contrato de $450mil en un mes para una firma de ingeniería en la AEE hasta que no se convenza de que no hay gato encerrao en esa contratación que dirige el jefe de la agencia, José Ortiz. Que haga lo mismo con las leyes aprobadas por RR2 antes de irse y cuestione el plan de uso de terrenos que amenaza con redesarrollar la costa de la Isla desplazando comunidades.Escucha este episodio completo y accede a todo el contenido exclusivo de Bonita Radio. Descubre antes que nadie los nuevos episodios, y participa en la comunidad exclusiva de oyentes en https://go.ivoox.com/sq/90599
La gobernadora Wanda Vázquez Garced detuvo el contrato de $450mil en un mes para una firma de ingeniería en la AEE hasta que no se convenza de que no hay gato encerrao en esa contratación que dirige el jefe de la agencia, José Ortiz. Que haga lo mismo con las leyes aprobadas por RR2 antes de irse y cuestione el plan de uso de terrenos que amenaza con redesarrollar la costa de la Isla desplazando comunidades.
E.l.e.m.n.t. is a in-house producer for Roc Marciano & Knowledge The Pirate he also produced your favourite intro to RR2 & a bulk of production on Lo’s past guest debut album Knowledge The Pirate. E.l.e.m.n.t & Lo talked about him growing up in New York in the 80s & 90s, park jams, being a emcee & finding his calling for being producer, getting his first placement with Grand Puba in 2012, working with Tone Atlas on the project Water To Wine, working with Knowledge The Pirate on the album Flintlock, finding is producer name & the way it’s styled, & much much more! Black Caesar coming soon!! Instagram: @fromthedeskoflo @e.l.e.m.n.t @kxnglo @datfeelinpodcast
2018 RubADickies Winners Rub-A-Dicker of the Year Luis Elizondo UBR Truth Seekers Top Contributor Patricia McBride UBR Trurh Seekers Top Moderators Jeff Aldrich Billy Baker 2018 Super Sapien Award Ronny Dawson Astronomers Are Tracking Four Potential Interstellar Objects Now In Our Outer Solar System Arricle link: https://www.forbes.com/sites/brucedorminey/2018/11/30/astronomers-are-tracking-4-potential-interstellar-objects-now-in-our-outer-solar-system/#1628af4eb5c3 Using detailed computer models of asteroidal-type objects between the Sun and Jupiter, two Harvard University researchers find that at least four known objects are likely to have origins from outside our solar system. After becoming gravitationally-trapped, the four potentially interstellar objects — 2011 SP25, 2017 RR2, 2017 SV13, and 2018 TL6 — are thought to spend most of their time between the orbits of Jupiter and Neptune. In a paper submitted to the Monthly Notices of the Royal Astronomical Society, Harvard co-authors Amir Siraj and Abraham Loeb, compare the orbital characteristics of theoretical high-inclination objects to those of the centaurs, the most similar population of known asteroids. “We find that there should be hundreds of Oumuamua-size interstellar objects identifiable by Centaur-like orbits,” write the authors. 1I/2017 U1 Oumuamua, the first bona fide interstellar object, was discovered Oct. 19, 2017 by the University of Hawaii's Pan-Starrs telescope. But the authors note that there should be at least 66 possible other interstellar objects in their calculations, ranging in diameter from roughly 100 meters to 10 kilometers in size. And all of these potential interstellar interlopers should be detectable by the LSST (Large Synoptic Survey Telescope), currently under construction in Chile. “ We do not know if they are comets, asteroids, or artifacts ,” Amir Siraj, a Harvard University undergraduate in astrophysics, told me They pass near Earth on timescales of some 20 to 120 years so it will be another 20 years until we can photograph one of them, he says. Show Stuff TeePublic Store - Get your UBR goodies today! http://tee.pub/lic/2GQuXxn79dg UBR Trurh Seekers Facebook Group: https://www.facebook.com/groups/216706068856746 Manny Moonraker: https://www.facebook.com/MannyMoonraker/ UFO Buster Radio: https://www.facebook.com/UFOBusterRadio YouTube Channel: https://www.youtube.com/channel/UCggl8-aPBDo7wXJQ43TiluA Google Plus Manny's Updated Google+ Profile: https://plus.google.com/u/0/+MannyMoonraker To contact Manny: manny@ufobusterradio.com, or on Twitter @ufobusterradio Call the show anytime at (972) 290-1329 and leave us a message with your point of view, UFO sighting, and ghostly experiences or join the discussion on www.ufobusterradio.com For Skype Users: bosscrawler
2018 RubADickies Winners Rub-A-Dicker of the Year Luis Elizondo UBR Truth Seekers Top Contributor Patricia McBride UBR Trurh Seekers Top Moderators Jeff Aldrich Billy Baker 2018 Super Sapien Award Ronny Dawson Astronomers Are Tracking Four Potential Interstellar Objects Now In Our Outer Solar System Arricle link: https://www.forbes.com/sites/brucedorminey/2018/11/30/astronomers-are-tracking-4-potential-interstellar-objects-now-in-our-outer-solar-system/#1628af4eb5c3 Using detailed computer models of asteroidal-type objects between the Sun and Jupiter, two Harvard University researchers find that at least four known objects are likely to have origins from outside our solar system. After becoming gravitationally-trapped, the four potentially interstellar objects — 2011 SP25, 2017 RR2, 2017 SV13, and 2018 TL6 — are thought to spend most of their time between the orbits of Jupiter and Neptune. In a paper submitted to the Monthly Notices of the Royal Astronomical Society, Harvard co-authors Amir Siraj and Abraham Loeb, compare the orbital characteristics of theoretical high-inclination objects to those of the centaurs, the most similar population of known asteroids. “We find that there should be hundreds of Oumuamua-size interstellar objects identifiable by Centaur-like orbits,” write the authors. 1I/2017 U1 Oumuamua, the first bona fide interstellar object, was discovered Oct. 19, 2017 by the University of Hawaii's Pan-Starrs telescope. But the authors note that there should be at least 66 possible other interstellar objects in their calculations, ranging in diameter from roughly 100 meters to 10 kilometers in size. And all of these potential interstellar interlopers should be detectable by the LSST (Large Synoptic Survey Telescope), currently under construction in Chile. “ We do not know if they are comets, asteroids, or artifacts ,” Amir Siraj, a Harvard University undergraduate in astrophysics, told me They pass near Earth on timescales of some 20 to 120 years so it will be another 20 years until we can photograph one of them, he says. Show Stuff TeePublic Store - Get your UBR goodies today! http://tee.pub/lic/2GQuXxn79dg UBR Trurh Seekers Facebook Group: https://www.facebook.com/groups/216706068856746 Manny Moonraker: https://www.facebook.com/MannyMoonraker/ UFO Buster Radio: https://www.facebook.com/UFOBusterRadio YouTube Channel: https://www.youtube.com/channel/UCggl8-aPBDo7wXJQ43TiluA Google Plus Manny's Updated Google+ Profile: https://plus.google.com/u/0/+MannyMoonraker To contact Manny: manny@ufobusterradio.com, or on Twitter @ufobusterradio Call the show anytime at (972) 290-1329 and leave us a message with your point of view, UFO sighting, and ghostly experiences or join the discussion on www.ufobusterradio.com For Skype Users: bosscrawler
Repasamos los anuncios de Apple, saltándonos las descripciones y lanzándonos de lleno a especular. Quintet es un juego iOS, Mac, Windows que permite simular una nave espacial con pantallas diferentes para cada componente de la tripulación. Quintet https://www.quintet.us/ Scrabble en iPad puede servir solo como tablero y permitir usar iPhones para las fichas de los jugadores Scrabble iOS http://www.pocketgamer.co.uk/r/iPad/Scrabble+(iPad)/news.asp?c=19586 Real Racer 2 permite usar iPhone como mandos e información de la pista Real Racer 2 http://www.redmondpie.com/wp-content/uploads/2011/10/RR2_partyplay_blog.jpeg FIFA iPad con iPhone como mando http://www.destructoid.com/using-an-iphone-to-play-fifa-12-ios-on-an-ipad-and-tv-205675.phtml Apple Prohibe Juegos que requieran mando en AppleTV http://www.gamasutra.com/view/news/253683/Apple_forbids_devs_from_requiring_a_controller_for_Apple_TV_games.php Video de Microsoft sobre latencia en pantallas táctiles https://www.youtube.com/watch?v=vOvQCPLkPt4 Diseñando software con la latencia táctil en mente https://www.youtube.com/watch?v=sazLd-pgpGc GridPad 1992 con teclado plegable y stylus http://research.microsoft.com/en-us/um/people/bibuxton/buxtoncollection/detail.aspx?id=168 802.11ad http://www.moorinsightsstrategy.com/qualcomm-gets-the-jump-on-wigig-60-ghz-wireless-with-wilocity-acquisition/ MU-MIMO http://www.moorinsightsstrategy.com/qualcomm-stealing-broadcoms-wi-fi-thunder-with-new-mu-mimo-technology/ nVidia Shield http://shield.nvidia.com/android-tv Desarrollo en JavaScript para OS X Yosemite http://tylergaw.com/articles/building-osx-apps-with-js Desarrollo en JavaScript para Apple TV https://www.simononstartups.com/developing-for-the-apple-tv-with-tvos-swift-javascript-and-tvml/ Lápiz Crayola electrónico para iPad http://www.actualidadipad.com/ya-esta-disponible-el-lapiz-crayola-colorstudio-hd-para-el-ipad/
Finally with new found freedom and adventure set to line the rest of our summer it felt like time to crush those dreams and knuckle down to some internet scouring for some great new tracks to share. Hopefully it paid off in the raucous party that is Baby Baby, as well as local (for us) Brighton act Twin Brother, and gladly rejuvenating our loves for the rebranded ∆ and LA Hip Hop trio Goldenwest.Track list is also as follows:RR 1Baby Baby - Breakin'RR2Twin Brother - LungsRR3∆ - BreezeblocksRR4Goldenwest - Lover's Names