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Hemos tenido una semana muy completa probando muchas novedades de la marca china Zontes, nada menos que cuatro scooter de media cilindrada y la deportiva 703 RR con motor de tres cilindros, de la que disfrutamos en tramos de carretera y en circuito. También hablaremos del Mundial SBK donde ha habido muchas noticias esta semana. La más importante es que el campeón del mundo Toprak Razgatlioglu se va a MotoGP; también Alvaro Bautista es noticia con su marcha de Ducati. Por último estuvimos de viaje al GP de Aragón en una Honda Hornet 750 de la que sacamos algunas conclusiones de su comportamiento en carretera. Recuerda que puedes enviarnos todas tus dudas o sugerencias al correo electrónico redaccion@moto1pro.com o bien dejar tus comentarios en Ivoox, Youtube o en la red de podcast que utilices.
Jennifer Dickenson is an author, cancer survivor, lawyer and wellness advocate. In 2011 she was diagnosed with brain cancer, grade 4, glioblastoma. She has been in remission since 2012. Through her experience fighting brain cancer she discovered many healing tools that she now shares with others. When she read Kelly Turner's book Radical Remission in 2014, she actually wept with joy because the tools Turner researched matched exactly with Dickenson's organic path to healing. What a blessing that was. website: www.JenniferDickenson.com Instagram: https://www.instagram.com/jenniferldickenson/ Facebook: https://www.facebook.com/Jennifer.DickensonWrites Linkedin: https://www.linkedin.com/in/jennifer-dickenson-11638b11/ Linktree: https://linktr.ee/jenniferdickenson ______________________ To learn more about the 10 Radical Remission Healing Factors, connect with a certified RR coach or join a virtual or in-person workshop visit www.radicalremission.com. To watch Episode 1 of the Radical Remission Docuseries for free, visit our YouTube channel here. To purchase the full 10-episode Radical Remission Docuseries visit Hay House Online Learning. To learn more about Radical Remission health coaching with Liz or Karla, Click Here Follow us on Social Media: Facebook Instagram YouTube __________________________ Connect & Thrive (CAT) is a heart-centered social impact company dedicated to supporting cancer previvors, patients, thrivers, and caregivers. CAT empowers women on their personal healing journeys by connecting them to our Marketplace of reputable practitioners and curated products. Our partners offer evidence-based healing modalities and healthy living products designed to prevent cancer, navigate a cancer diagnosis, and mitigate the risk of recurrence. CAT's mission is to help women CONNECT with a community of partners who can help them THRIVE! Asking for, and accepting, help are signs of strength, not weakness. “In the face of uncertainty, there is nothing wrong with hope.” ~O. Carl Simonton Visit Connect-and-thrive.com
Joana Marques apresenta-nos o Príncipe do Havai e Ana Galvão consegue um feito inédito: ganhar "A última a saber".
"O Juiz de Cid", uma audiência inédita em tribunal, ou melhor, no estúdio, e episódio do "Alerta Estupidez" dedicado ao fenómeno dos Labubus.
Joana Marques apresenta-nos Sua Alteza Real, D. Alfredo I, Príncipe do Havai.
Ana Galvão viaja até 1994 e relembra o programa "Onda de Verão" apresentado por Luís Pereira de Sousa. Revisitamos os clássicos anúncios aos quais já nos habituámos.
An expert panel highlights key presentations in multiplemyeloma, lymphoma, and other hematologic malignancies at the 2025 ASCO Annual Meeting.CancerNetwork®, in collaboration with The American Societyfor Transplantation and Cellular Therapy (ASTCT), organized an X Space hosted by Rahul Banerjee, MD, FACP; Taha Al-Juhaishi, MD; and Muhammad Salman Faisal, MD. This expert panel convened to discuss key presentations and abstracts of interest at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting featuring noteworthy developments in modalities like CAR T-cell therapy and transplantation across multiple myeloma, lymphoma, and other disease types.Banerjee is an assistant professor in the Clinical Research Division at the Fred Hutchinson Cancer Center in Seattle, Washington. Al-Juhaishi is the associate director of the Hematopoietic Stem Cell Transplantation and Cell Therapy Program at Oklahoma University Health Stephenson Cancer Center and an assistant professor of medicine at the University of Oklahoma College of Medicine. Faisal is a hematologist/oncologist at Oklahoma University HealthStephenson Cancer Center and serves as an ambassador for ASCO.The group highlighted several late-breaking abstracts,plenary sessions, and poster presentations focused on significant clinical trial data and other findings across the hematologic oncology landscape. Topics of interest included the following:Phase 1b/2 CARTITUDE-1 trial (NCT03548207,NCT05201781)1Long-term follow-up showed that approximately one-third(33%; n = 32) of patients with relapsed/refractory multiple myeloma maintained progression-free status for at least 5 years following a single infusion of ciltacabtagene autoleucel (cilta-cel; Carvykti). An equal likelihood of progression-free survival occurred in patients with high-risk cytogenetics or extramedullary plasmacytomas.With a median follow-up of 61.3 months, the median overall survival (OS) with cilta-cel was 60.7 months (95% CI, 41.9-notevaluable [NE]). Real-world axicabtagene ciloleucel (axi-cel; Yescarta) use2Across inpatient and outpatient treatment settings, safety and efficacy outcomes were comparable for patients who received axi-cel for relapsed/refractory large B-cell lymphoma.Multivariate analysis showed no associations between intended care setting and cytokine release syndrome or immune effector cell-associated neurotoxicity syndrome.Investigators noted that these real-world data support the consideration of axi-cel in appropriate outpatient settings.Phase 1b/2 NEXICART-2 trial (NCT06097832)3Investigators assessed NXC-201, a sterically optimized CAR T construct, as a treatment for patients with relapsed/refractory light chain amyloidosis, a population with no FDA-approved options.Among 12 patients who received the agent at 450x 106 cells, 100% achieved rapid and deep hematologic responses at a median time to first and best response of 7 and 26 days, respectively. With a median follow-up of 121 days (range, 29-289), no hematologic relapses or progression had occurred.References1. Voorhees P, Martin T, Lin Y, et al. Long-term (≥5 year) remission and survival after treatment with ciltacabtagene autoleucel (cilta-cel) in CARTITUDE-1 patients (pts) with relapsed/refractory multiple myeloma (RRMM). J Clin Oncol. 2025;43(suppl 16):7507. doi: 10.1200/JCO.2025.43.16_suppl.75072. Furqan F, Hemmer M, Tees M, et al. Trends and outcomes by inpatient and outpatient infusion of axicabtagene ciloleucel (axi-cel) in the US for patients (pts) with relapsed/refractory large B-celllymphoma (R/R LBCL). J Clin Oncol. 2025;43(suppl 16):7023. doi:10.1200/JCO.2025.43.16_suppl.70233. Landau H, Hughes C, Rosenberg A, et al. Safety and efficacy data from Nexicart-2, the first US trial of CAR-T in R/R light chain (AL) amyloidosis, Nxc-201. J Clin Oncol. 2025;43(suppl 16):7508.doi:10.1200/JCO.2025.43.16_suppl.7508
Un fin de semana caótico que concluye con nuevos frentes de guerra en Oriente Medio y protestas en Occidente: qué pasa entre Israel e Irán y cuál es el pulso de los mercados, también las protestas en Estados Unidos contra Trump, así como lo que debemos esperar a partir de este lunes con la reunión de los países del G7 en Canadá, incluida la presidenta Sheinbaum, quien se verá cara a cara por primera vez con el presidente de Estados Unidos. Muere la primera mujer presidenta en América Latina y en México una Sofipo es intervenida. Patrocinado] Conoce Deel, la plataforma de RR.HH. en la que confían miles de empresas en todo el mundo para gestionar y pagar a sus equipos globales. - Conoce más
O momento em que Telavive é atingido por mísseis iranianos. Há pelo menos oito mortosb4f
Early last month, lawmakers in Washington state enacted a new law, set to take effect in late July, that will mandate Catholic priests to report child abuse they learn about in the context of confession — forcing priests to risk automatic excommunication from the Church for breaking the sacramental seal. What does this mean for the Church in the Northwest and across the country in other legislative hot spots? This week on RR we are joined by Register staff writer Jonah McKeown. And then, a month has passed since the election of Pope Leo XIV and Register Senior Editor Jonathan Liedl discusses how the new pontiff has settled in and what we can discern about his impending decisions.
Israel diz que Irão pagará "preço elevado" por matar civis. Ataques com mísseis continuam no Médio Oriente
Early last month, lawmakers in Washington state enacted a new law, set to take effect in late July, that will mandate Catholic priests to report child abuse they learn about in the context of confession — forcing priests to risk automatic excommunication from the Church for breaking the sacramental seal. What does this mean for the Church in the Northwest and across the country in other legislative hot spots? This week on RR we are joined by Register staff writer Jonah McKeown. And then, a month has passed since the election of Pope Leo XIV and Register Senior Editor Jonathan Liedl discusses how the new pontiff has settled in and what we can discern about his impending decisions.
José Condessa em Nova Iorque para estrear o seu novo filme "Honeyjoon"0925f3e1-1049-f011-8
Joana Marques mostra-nos o inesperado e surpreendente encontro entre Sónia Quim Costa e Romilda, o ecógrafo humano.
Pedidos de Anda Paula a caminho do hospital, notícias cor-de-rosa que podem ser falsas e uma vidente que vê mal.
Israel lança ataque ao Irão. Netanyahu promete eliminar ameaça nuclear4412b382-3948-f011
Watch Party em Nova Iorque com Whoopi Goldberg, Chazz Palminteri e José Condessa824677ea-6
"Israel começou uma guerra". Irão responde com ataque a Telavive e Jerusalém359b1f8e-944
Joana Marques fala-nos da amizade adulta de Mariana Ribeiro, Inês Prata e Mariana Azevedo. E pelo caminho descobre o que é um haul e um solo date.
While our host enjoys some well-earned R&R, we're cracking open the Six Figure Trucker vault to revisit one of our most powerful conversations. We've got part two of our conversation with Peter Rizzo. As you heard last week, Peter is one of our top drivers and one that excels in logistics. In part two, we dive into Peter's incredible backstory. Before he was a fixture in a Big Rig, our guest today spent most of his days in the Big Apple. As a kid growing up playing basketball on the streets of Long Island, 6 foot 8 inch Peter Rizzo was often called a “Skyscraper.” He went on to play hoops in college before returning to the City as a police officer in the land of skyscrapers. But, within his first few months on the job, two of those towers came down. But, when the unthinkable occurred, Peter Rizzo joined his comrades and jumped straight into the fire to do what he could to rescue lives and restore a city. We thank him for his service, and we're honored to revisit this conversation today as he shares some of his memories of that time on the force with the NYPD. Don't miss this conversation with one of our nation's finest on this episode of the #SixFigureTrucker The Six-Figure Trucker is a weekly podcast about driveaway trucking brought to you by Norton Transport. For more information or to subscribe, please visit Six-FigureTrucker.com.
Para comemorar os 40 anos da adesão de Portugal à CEE, temos repórteres na rua – maioritariamente em pastelarias – descobrimos um grupo anti-União Europeia no Alentejo e a Dona Virgínia fala sobre essas coisas da Europa.
こんにちは。姿勢治療家(R)仲野孝明です。 この番組では、体の姿勢と生きる姿勢、より豊かに人生を生きるための姿勢力について話をさせていただいてます。 今回は、姿勢治療家(R)が考える健康の要素、6ヘルス(構造・睡眠・食・運動・精神・呼吸)の中の構造 前回、肩甲帯(鎖骨・肩甲骨・上腕骨)を動かそう!という配信でした。動かすには、筋肉を少しでも知っていると、もっと動かしやすくなります。 今回は、肩甲骨を動かす筋肉たちを紹介しました。 体を見直す時間は、人生を見直す時間です。 ■Youtube|姿勢治療家の「姿勢の医学」チャンネル 正しい姿勢と正しいカラダの使い方配信中 https://www.youtube.com/user/nakanoseitai ■twitter|勢治療家仲野孝明公式 https://twitter.com/sisei_nakano ■有料動画講座|いつでもどこでも学べる姿勢 一般社団法人 日本姿勢構造機構 https://shiseikk.jp/vimeo/ ■メルマガ登録|仲野孝明メールマガジン 6ヘルスを軸にした日々の気づきコラム配信中。 http://takaakinakano.com/mail-register/ ■オンラインSHOP|姿勢治療家印のグッズ販売 自分が使いたい商品をつくっちゃいました https://shop.senakano.jp/ ■公式ページ|姿勢治療家仲野孝明 http://takaakinakano.com/ ■仲野整體東京青山|姿勢治療家HEADOFFICE 治療のご相談はこちら https://senakano.jp/
Avião com sete portugueses a bordo despenhou-se na Índia405ad126-7747-f011-8f7b-00224889d
Joana Marques não foi convidada para o podcast "Amiga, faz parte", até porque não reúne os requisitos necessários, mas resolveu ir na mesma.
Jerome was diagnosed with muscle invasive bladder cancer on January 29, 1997. The diagnosis was based on a transurethral resection surgery. Having done his research, he contacted a doctor at Harvard and Mass General Hospital about a clinical trial for a bladder sparing protocol. To Jermoe's surprise, Dr.Shipley called back and shared the protocol with Jerome's medical team and the treatment began a couple of weeks later. The treatment involved chemotherapy in conjunction with radiation therapy. Jerome experienced several recurrences over the years, each time treating them with surgery and infusions. In 2018 a recurrence involved hospitalization and tubes were placed in each kidney. This time Jerome was faced with a decision to have a radical cystectomy or given the choice to do immunotherapy. By 2019 there was little evidence of bladder cancer and infusions continued, with no side effects. He still has a tube in one kidney and is otherwise thriving! email: Jerome@mountainsangha.org phone: 415-299-0428 website: www.mountainsangha.org Book: Healing with the 7 Principles of Mindfulness, by Jerome FreedmanHere is what Dr. Kelly Turner, PhD has to say about Healing with the 7 Principles of Mindfulness: “Dr. Freedman speaks from experience, both as a cancer survivor himself, and the father of a Radical Remission cancer survivor. His book, “Healing with the 7 Principles of Mindfulness” gives readers a nurturing, helping hand throughout the entire cancer journey, especially with regard to developing a meditation practice. –Kelly Turner, PhD, Author of the NYTimes Bestseller “Radical Remission: Surviving Cancer Against All Odds” Stop Cancer in Its Tracks: How to Embrace Mindfulness In Healing by Jerome Freedman ___________________________ To learn more about the 10 Radical Remission Healing Factors, connect with a certified RR coach or join a virtual or in-person workshop visit www.radicalremission.com. To watch Episode 1 of the Radical Remission Docuseries for free, visit our YouTube channel here. To purchase the full 10-episode Radical Remission Docuseries visit Hay House Online Learning. To learn more about Radical Remission health coaching with Liz or Karla, Click Here Follow us on Social Media: Facebook Instagram YouTube __________________________ Thank you to our friends from The Healing Oasis for sponsoring this episode of the podcast. The Healing Oasis is a first of its kind in beautiful British Columbia, Canada where we encourage the body to heal from cancer using alternative therapies & cancer fighting meals at a wellness retreat center in nature. Our top naturopathic cancer doctor will prescribe a protocol tailored specifically for you. There's no place quite like it. Start your healing journey today! Learn More about The Healing Oasis by visiting these links: Website Testimonials Video Overview
A Quarta da Manhã é o ator Vasco Pereira Coutinho e traz em exclusivo a análise da atualidade pela famosíssima Tia Bli
Veja as imagens do ataque ao carro de adeptos do FC Porto por apoiantes do Sportingea50407d
¿Conoces la historia del marketing? ¿Cómo se vendían productos antes del marketing digital? En este episodio hablamos con Ana Calleja, autora del libro Pioneros del marketing, para descubrir 8 campañas fascinantes —desde ladrillos en la antigua Roma hasta coches de lujo— que siguen tan vigentes como el primer día.Ana es licenciada en Publicidad y RR.PP., tiene más de 10 años de experiencia en comunicación, y ha trabajado con marcas como Blizzard, Bethesda o Star Alliance. Actualmente es cofundadora de Ziran Communication, una agencia internacional de Relaciones Públicas y Redes Sociales que opera en siete países.
Veja o momento em que o general Eanes foi condecorado no 10 de Junhoedc64910-1946-f011-8f7b
Joana Marques deseja ir de férias, mas não férias como as da influencer Mia Relógio.
A loucura volta a estúdio depois do Três por Todos. A Ana, Joana e Inês submetem-se à prova de português dos alunos do segundo ano e testam quantas palavras lêem por minuto. Mas de textos do século XIII.
Nos metimos hasta la sala de Consejo de la Bolsa Mexicana de Valores para platicar con su presidente, Marcos Martínez Gavica, ahora que sus líderes comienzan a accionar varias estrategias para atraer a más ahorradores al mundo bursátil, también adelanta la fecha de operación del mercado de electrónico de bonos, algo muy esperado por el mercado, y la pregunta recurrente y obligada sobre cuándo se verán los frutos de la Ley del Mercado de Valores. [Patrocinado] Conoce Deel, la plataforma de RR.HH. en la que confían miles de empresas en todo el mundo para gestionar y pagar a sus equipos globales. - Conoce más
N Engl J Med 2001;345:1667-1675Background: Angiotensin II is a peptide hormone that is part of the renin–angiotensin–aldosterone system (RAAS). Angiotensin II is a potent vasoconstrictor and growth-stimulating hormone. Data suggested that it plays a role in ventricular remodeling and progression of heart failure. Although treatment with angiotensin-converting enzyme inhibitors (ACEi) reduce angiotensin II levels, physiologically active levels of angiotensin II may persist despite long-term therapy.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber.The Valsartan Heart Failure Trial (Val-HeFT) sough to assess whether the angiotensin-receptor blocker valsartan, could reduce mortality and morbidity when added to optimal medical therapy in patients with systolic heart failure.Patients: Eligible patients had left ventricular ejection fraction less than 40% and left ventricular dilation, in addition to having clinical heart failure for at least 3 months with NYHA class II, III or IV symptoms. Patient also had to have been receiving a fixed-dose drug regimen for at least two weeks, that could include ACEi, diuretics, digoxin, and beta-blockers.There were many exclusion criteria. We mention some here: Postpartum cardiomyopathy, acute myocardial infarction within 3 months, coronary artery disease likely to require intervention, serum creatinine >2.5 mg/dL and life expectancy less than 5 years.Baseline characteristics: Patients were recruited from 302 centers in 16 countries. The trial randomized 5,010 patients – 2,511 randomized to receive valsartan and 2,499 to receive placebo.The average age of patients was 63 years and 80% were men. The average left ventricular ejection fraction was 27%. Cardiomyopathy was ischemic in 57% of the patients. The NYHA class was II in 62% of the patients, III in 36% of the patients and IV in 2%.Approximately 26% had diabetes and 12% had atrial fibrillation.At the time of enrollment, 86% were taking a diuretic, 67% were taking digoxin, 35% were taking beta-blockers, and 93% were taking ACEi.Procedures: The trial was double-blinded. The trial had an initial run-in period for 2 - 4 weeks where patients received placebo twice daily. This was performed to confirm patients' eligibility, clinical stability and compliance.Patients were assigned in a 1:1 ratio to receive valsartan or placebo. Randomization was stratified according to whether or not they were receiving a beta-blocker.Valsartan was started at a dose of 40 mg twice a day, and the dose was doubled every two weeks to the target dose of 160 mg twice a day. Placebo doses were adjusted in a similar way.Follow up occurred at 2, 4, and 6 months and every 3 months thereafter.Endpoints: The trial had two primary end points. The first was all-cause mortality. The second was the combined end point of mortality and morbidity, which was defined as cardiac arrest with resuscitation, hospitalization for heart failure, or administration of intravenous inotropic or vasodilator drugs for four hours or more without hospitalization.The estimated sample size was 5,000 patients. The sample size calculation assumed 20% relative risk reduction in mortality with valsartan assuming 906 patients would die during the trial. This sample size would provide the trial 90% power at 0.02 alpha. Alpha was 0.02 instead of the traditional 0.05 since the trial had two primary endpoints and to adjust for the interim analyses.Results: The target valsartan dose of 160 mg twice a day was achieved in 84% of the patients. The reduction in systolic blood pressure was greater with valsartan vs placebo – mean of 5.2 ± 15.8 mm with valsartan compared to 1.2 ± 14.8 mm Hg with placebo, at 4 months.All-cause mortality was not different between both groups (19.7% with valsartan vs 19.4% with placebo, RR: 1.02, 95% CI: 0.88 – 1.18; p= 0.80). The second co-primary endpoint was reduced with valsartan (28.8% vs 32.1%, RR: 0.87, 95% CI: 0.77 – 0.97; p= 0.009). This was driven by reduction in hospitalizations for heart failure (13.8% vs 18.2%). Cardiac arrest with resuscitation was 0.6% with valsartan and 1.0% with placebo. All-cause hospitalization was numerically lower with valsartan, however, this was not statistically significance (2,856 vs 3,106; p= 0.14). The mean change in ejection fraction was higher with valsartan (4.0% vs 3.2%; p= 0.001). More patients had improvement in NYHA classification with valsartan (23.1% vs 20.7%; p
While our host enjoys some well-earned R&R, we're cracking open the Six Figure Trucker vault to revisit one of our most insightful conversations — with none other than Peter Rizzo.Peter's not just a top-tier driveaway driver — he's a master of the craft. Known for his near-perfect on-time delivery rate, Peter's secret weapon is simple but powerful: planning. In this episode, he breaks down how thoughtful logistics can turn chaos into consistency — and why preparation equals profit.Whether you're new to driveaway or looking to level up, consider this your masterclass in “Driveaway 101.” Grab a notepad, and let Peter Rizzo show you how it's done — only on this episode of the #SixFigureTrucker. The Six-Figure Trucker is a weekly podcast about driveaway trucking brought to you by Norton Transport. For more information or to subscribe, please visit Six-FigureTrucker.com.
Tara Graham is a Certified Integrative and Functional Nutritionist and Certified Terrain Advocate in Oncology Nutrition with a Degree in Complementary and Alternative Medicine. After her mother's terminal cancer diagnosis in 2014, Tara embarked on a mission to discover the root cause of disease. She redefines the relationship with nourishment and food to uncover true healing within illness to include alternative cancer treatment and prevention, with a deep understanding of the intricacies of bio individuality and profound wellness. IG- @tarafuntionalhealth Website: www.tarafunctionalhealth.com Email: tara@tarafunctionalhealth.com _______________ To learn more about the 10 Radical Remission Healing Factors, connect with a certified RR coach or join a virtual or in-person workshop visit www.radicalremission.com. To watch Episode 1 of the Radical Remission Docuseries for free, visit our YouTube channel here. To purchase the full 10-episode Radical Remission Docuseries visit Hay House Online Learning. To learn more about Radical Remission health coaching with Liz or Karla, Click Here Follow us on Social Media: Facebook Instagram YouTube
Joana Marques descobre quem é o médico de família de Gustavo Santos, e no fim acaba tudo (quase) nu, numa banheira de água gelada.
Title – Ascites Episode description RR discuss a case of ascites Student discount https://www.rlrcpsolvers.com/student-discounts/ IMG discount Use coupon code RLRIMG at check out https://rlrcpsolvers.com/annual-plan